A fast-switching three-channel quantitative pipette

Abstract

The present invention discloses a fast-switching three-channel quantitative pipette, which relates to the technical field of pipettes and comprises a barrel, a gun head tube being provided at the center of the bottom end of the barrel, a negative pressure liquid suction component and three groups of quantitative liquid suction structures. The fast-switching three-channel quantitative pipette has three specifications of negative pressure containers, i.e., quantitative tubes, directly built in, and switches between the three negative pressure containers in a manner similar to a multi-color ballpoint pen. After switching, negative pressure suction is performed to accurately extract liquids of different capacities. This method can first solve the tedious operation of users frequently changing gun heads due to different liquid measurements, and saves economic costs. The three-channel range pipette is also more convenient and quick in maintenance and calibration, saving costs. Especially in some laboratories with limited funds, the three-channel range pipette of this device can basically meet all experimental needs and complete various large-scale or precise sample addition requirements.

Description

Technical Field

[0001] The present invention relates to the technical field of liquid transfer guns, in particular to a fast-switching three-channel quantitative liquid transfer gun. Background Art

[0002] Pipettes typically work using the air displacement principle. By pressing or turning a button, the user draws air into or out of the pipette tip, creating or eliminating a pressure differential that is used to draw in or release liquid. There are many different brands and models of pipettes available on the market. Advantages of current pipettes include:

[0003] 1. High precision: The pipette can accurately measure and transfer tiny amounts of liquid, which is essential for experiments that require precise control of reagent dosage.

[0004] 2. Easy to operate: Pipettes are designed to be relatively lightweight and easy to operate with one hand, and many models offer adjustable volume settings, allowing users to easily adapt to different experimental needs.

[0005] 3. Good repeatability: Pipette guns usually have good repeatability, which means that when the same amount of liquid is measured multiple times under the same conditions, the results obtained are highly consistent.

[0006] 4. Wide range of applications: The capacity of pipettes ranges from less than 1 microliter to several milliliters, which is suitable for various biological experiments.

[0007] However, the existing pipettes still have the following deficiencies:

[0008] 1. High cost of use: Although the price of the pipette itself may not be expensive, in large-scale, high-throughput experiments, operators need to constantly use the pipette to transfer liquids, which may lead to an increase in the overall cost of use.

[0009] 2. Different experiments require different pipette ranges, so for experiments with complex sample volumes, pipettes need to be replaced frequently; when multiple people in the laboratory are doing experiments at the same time, there may be a shortage of pipettes. Summary of the Invention

[0010] In view of the deficiencies in the prior art, the present invention provides a fast-switching three-channel quantitative pipette, which solves the deficiencies of the existing pipettes.

[0011] To achieve the above objectives, the present invention is implemented through the following technical solutions: a fast-switching three-channel quantitative pipette, comprising a barrel, a gun head tube is provided at the center of the bottom end of the barrel, and further comprising:

[0012] The negative pressure liquid suction component is fixedly connected to the middle of the barrel and is coaxially arranged with the barrel. It generates negative pressure by pressing to absorb liquid;

[0013] Three sets of quantitative liquid aspiration structures are evenly distributed around the periphery of the negative pressure liquid aspiration component, and the three sets of quantitative liquid aspiration structures can absorb different capacities of liquid. By inserting the bottom ends of the different quantitative liquid aspiration structures into the gun head tube and sealing the gun head tube, when negative pressure is generated in the space below the negative pressure liquid aspiration component, liquid is aspirated through the quantitative liquid aspiration structures located in the gun head tube. In addition, a limiting structure is provided on the gun barrel to prevent the quantitative liquid aspiration structure from sliding downward and resetting due to accidental touch.

[0014] Three sets of guide plates are arranged at the bottom of the inner cavity of the gun barrel and are staggered with the three sets of quantitative liquid suction structures to guide the quantitative liquid suction structures to move radially.

[0015] Preferably, the negative pressure liquid suction component includes:

[0016] A flange, fixedly connected to the middle of the barrel;

[0017] The negative pressure tube is coaxially fixed to the top of the flange, and the center of the flange is located inside the negative pressure tube and is hollowed out;

[0018] a first piston, slidably connected to the interior of the negative pressure tube;

[0019] A pressing rod, fixedly connected to the top of the first piston and used to press the first piston downward;

[0020] The first elastic member is elastically abutted between the first piston and the flange to rebound and reset the first piston after being pressed downward.

[0021] Preferably, the quantitative liquid absorption structure comprises:

[0022] The quantitative tube is needle-shaped and has a bottom outer diameter smaller than the inner diameter of the gun head tube. The length of the quantitative tube is greater than the length of the gun head tube, so that the bottom end of the quantitative tube can be extended from the bottom after being inserted into the gun head tube;

[0023] A second piston is slidably disposed inside the metering tube;

[0024] The positioning ring is arranged on the inner wall of the quantitative tube and is located above the second piston. The positioning rings of the three sets of quantitative liquid suction structures have different heights, so that the second piston slides up to different distances, thereby extracting different capacities of liquid;

[0025] The sealing ring is fixedly mounted on the outside of the bottom end of the quantitative tube and is used to seal the gun head tube.

[0026] Preferably, the top end of the quantitative tube is rotatably connected to a sliding rod through a connecting rod, and the sliding rod slides through a flange, and a sealing rubber sleeve is penetrated inside the flange and is sleeved on the outside of the sliding rod. The top end of the sliding rod is thickened, and a second elastic member is sleeved on the outside of the sliding rod and located between the thickened section and the flange for resetting the quantitative tube. The top end of the sliding rod is fixed with a clamping structure that engages with the gun barrel to limit the height of the quantitative tube.

[0027] Preferably, the clamping structure includes a spring piece connected to the top of the sliding rod, the top of the spring piece is bent outward, and the bottom of the bent part is set as a wedge-shaped surface, a push rod is protruding in the middle of the bent part of the spring piece, and the front section of the push rod is set as a sliding structure, which pushes the sliding structure to push the spring piece to bend and slide down.

[0028] Preferably, an I-shaped groove is provided on the side of the gun barrel, the horizontal section width of the I-shaped groove is adapted to the width of the shrapnel, and the vertical section width of the I-shaped groove is adapted to the push rod.

[0029] Preferably, the limiting structure includes a sliding sleeve provided on the outside of the barrel and a limiting sleeve located below the I-slot, the inner wall of the limiting sleeve and the outer wall of the barrel are respectively provided with an upper convex ring and a lower convex ring, and a third elastic member is abutted between the upper convex ring and the lower convex ring, and the limiting sleeve is inserted between the slide and the barrel by the third elastic member to limit the slide from being pushed into the barrel.

[0030] Preferably, the top end of the gun barrel is threadedly connected to a top cover, the pressing rod slides through the top cover and a pressure cap is provided on the top end.

[0031] The present invention provides a fast-switching three-channel quantitative pipette. Compared with the prior art, it has the following advantages:

[0032] 1. This quick-switch three-channel quantitative pipette has three sizes of negative pressure containers, namely quantitative tubes, built directly in. It switches between the three negative pressure containers in a manner similar to a multi-color ballpoint pen. After switching, negative pressure suction is performed to accurately extract liquids of different volumes. This method can first solve the tedious operation of users frequently changing gun tips due to different liquid measurements, and it also saves economic costs. The three-channel range pipette is also more convenient and cost-effective in maintenance and calibration. Especially in some laboratories with limited funds, the three-channel range pipette of this device can basically meet all experimental needs and complete various large-scale or precise sample addition requirements. It saves time and labor costs and greatly improves experimental operation efficiency.

[0033] 2. The quick-switching three-channel quantitative pipette uses the upper and lower horizontal sections of the I-shaped groove to limit the bent part of the spring, so that the negative pressure liquid suction component can be limited to different heights. When it is stuck in the lower layer, the rebound of the second elastic member can be avoided, causing the negative pressure liquid suction component to slide up and off the gun head tube. The push rod can press the bent part of the spring out of the I-shaped groove, and on the other hand, it can slide down to drive the quantitative liquid suction structure as a whole to move it to the center and insert it into the gun head tube. The operation is simple and convenient. The set restriction structure can also avoid accidentally pressing the slide and causing the quantitative liquid suction structure to rebound and reset, making it more stable to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 A top perspective view of the structure of the present invention;

[0035] Figure 2 A bottom perspective view of the structure of the present invention;

[0036] Figure 3 is a cutaway perspective view of the structure of the present invention;

[0037] Figure 4 A top view of the layout of the guide plate and the quantitative tube of the present invention;

[0038] Figure 5 This is a schematic diagram of the structure inside the 10 μl quantitative tube of the present invention;

[0039] Figure 6 This is a schematic diagram of the structure inside the 20 μl quantitative tube of the present invention;

[0040] Figure 7 Schematic diagram of the structure inside the 100 μl quantitative tube of the present invention;

[0041] Figure 8 is a sectional perspective view of the negative pressure liquid suction assembly of the present invention;

[0042] Figure 9 It is a cross-sectional view of the restriction structure and the gun barrel of the present invention.

[0043] In the figure: 1-barrel, 11-gun head tube, 12-top cover, 13-I-slot, 14-guide plate;

[0044] 2-negative pressure liquid suction assembly, 21-flange, 22-negative pressure tube, 23-first piston, 24-pressing rod, 25-first elastic member;

[0045] 3- quantitative liquid aspiration structure, 31- quantitative tube, 32- second piston, 33- positioning ring, 34- sealing ring, 35- connecting rod, 36- sliding rod, 37- sealing rubber sleeve, 38- second elastic member, 39- shrapnel, 310- push rod;

[0046] 4-limiting structure, 41-limiting sleeve, 42-upper convex ring, 43-lower convex ring, 44-third elastic member. DETAILED DESCRIPTION

[0047] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0048] See Figures 1-9 , the present invention provides the following two technical solutions:

[0049] The first embodiment: A fast-switching three-channel quantitative pipette, comprising a barrel 1, wherein a gun head tube 11 is provided at the center of the bottom end of the barrel 1, and the bottom of the barrel 1 is tapered, further comprising:

[0050] The negative pressure liquid suction component 2 is fixedly connected to the middle of the barrel 1 and is coaxially arranged with the barrel 1, and sucks the liquid by generating negative pressure by pressing;

[0051] Three groups of quantitative liquid aspiration structures 3 are evenly distributed around the periphery of the negative pressure liquid aspiration component 2, and the three groups of quantitative liquid aspiration structures 3 can absorb different capacities of liquid. By inserting the bottom ends of the different quantitative liquid aspiration structures 3 into the gun head tube 11 and sealing the gun head tube 11, when negative pressure is generated in the space below the negative pressure liquid aspiration component 2, liquid is aspirated through the quantitative liquid aspiration structures 3 located in the gun head tube 11. In addition, a limiting structure is provided on the gun barrel 1 to limit the downward movement of the quantitative liquid aspiration structures 3 to prevent them from resetting due to accidental touch.

[0052] Three groups of guide plates 14 are arranged at the bottom of the inner cavity of the gun barrel 1 and are staggered with the three groups of quantitative liquid aspiration structures 3 to guide the quantitative liquid aspiration structures 3 to move radially.

[0053] In this embodiment, the negative pressure liquid suction component 2 includes:

[0054] Flange 21, fixedly connected to the middle of the barrel 1;

[0055] The negative pressure tube 22 is coaxially fixed to the top of the flange 21. The center of the flange 21 and the inner side of the negative pressure tube 22 are hollowed out. The hollowing out can maintain ventilation on the one hand and support the second elastic member 38 on the other hand.

[0056] The first piston 23 is slidably connected to the inside of the negative pressure tube 22;

[0057] The pressing rod 24 is fixedly connected to the top of the first piston 23 and is used to press the first piston 23 downward. The top of the barrel 1 is threadedly connected to the top cover 12. The pressing rod 24 slides through the top cover 12 and is provided with a pressure cap on the top. The pressure cap is connected by threading, sleeve connection or bonding to facilitate disassembly.

[0058] The first elastic member 25 is elastically in contact between the first piston 23 and the flange 21 to resiliently reset the first piston 23 after being pressed downward. The first elastic member 25 is a spring.

[0059] In this embodiment, the quantitative liquid absorption structure 3 includes:

[0060] The dosing tube 31 is needle-shaped and has a bottom outer diameter smaller than the inner diameter of the gun head tube 11. The length of the dosing tube 31 is greater than the length of the gun head tube 11, so that the bottom end of the dosing tube 31 can be inserted into the gun head tube 11 and then extended from the bottom. After being extended, the gun head can be put on to absorb the liquid.

[0061] The second piston 32 is slidably disposed inside the metering tube 31;

[0062] A positioning ring 33 is provided on the inner wall of the quantitative pipette 31 and above the second piston 32. The positioning rings 33 of the three sets of quantitative liquid aspiration structures 3 have different heights, which allows the second piston 32 to slide up to different distances, thereby extracting different volumes of liquid. The spaces for the second piston 32 to slide up in the three quantitative pipettes 31 are 10μl, 20μl, and 100μl, respectively. To distinguish the capacities of the three sets of quantitative liquid aspiration structures 3, corresponding numbers are marked under the three I-shaped grooves 13;

[0063] The sealing ring 34 is fixedly sleeved on the outer side of the bottom end of the quantitative tube 31 to seal the gun head tube 11.

[0064] The top end of the metering tube 31 is rotatably connected to a slide rod 36 through a connecting rod 35. The slide rod 36 slides through the flange 21. The interior of the flange 21 is penetrated by a sealing rubber sleeve 37 sleeved on the outside of the slide rod 36. The top end of the slide rod 36 is thickened. A second elastic member 38 is sleeved on the outside of the slide rod 36 and located between the thickened section and the flange 21 for reloading and resetting the metering tube 31. The second elastic member 38 is a spring. A clamping structure is fixed to the top end of the slide rod 36, which is engaged with the barrel 1 to limit the height of the metering tube 31, and a limiting structure 4 is provided on the outside of the barrel 1 for axial sliding to limit the rebound of the clamping structure.

[0065] The device directly has three specifications of negative pressure containers, namely quantitative tubes 31, built in, and uses a method similar to a multi-color ballpoint pen to switch the three negative pressure containers. After switching, negative pressure suction is performed to accurately extract liquids of different volumes. This method can first solve the tedious operation of users frequently changing gun tips due to different liquid measurements, and save economic costs. The three-channel range pipette is also more convenient and quick in maintenance and calibration, saving costs. Especially in some laboratories with limited funds, the three-channel range pipette of the device can basically meet all experimental needs, complete various large-scale or precise sample addition requirements, save time and labor costs, and greatly improve experimental operation efficiency.

[0066] The second embodiment is mainly different from the first embodiment in that the clamping structure includes a spring piece 39 connected to the top of the slide rod 36, the top of the spring piece 39 is bent outward, and the bottom of the bent part is set as a wedge surface, and a push rod 310 is protruding in the middle of the bent part of the spring piece 39, and the front section of the push rod 310 is set as a slide structure, which pushes the slide structure to push the spring piece 39 to bend and slide down.

[0067] An I-shaped groove 13 is provided on the side of the gun barrel 1 , the horizontal width of the I-shaped groove 13 is adapted to the width of the shrapnel 39 , and the vertical width of the I-shaped groove 13 is adapted to the push rod 310 .

[0068] The limiting structure 4 includes a sliding sleeve arranged on the outside of the barrel 1 and a limiting sleeve 41 located below the I-slot 13. The inner wall of the limiting sleeve 41 and the outer wall of the barrel 1 are respectively provided with an upper convex ring 42 and a lower convex ring 43, and a third elastic member 44 is abutted between the upper convex ring 42 and the lower convex ring 43. The third elastic member 44 is a spring. The upper convex ring 42 is pushed up by the third elastic member 44 to allow the limiting sleeve 41 to be inserted between the slide and the barrel 1 to limit the slide from being pushed into the barrel 1.

[0069] By utilizing the upper and lower horizontal sections of the I-groove 13 to restrict the bent portion of the spring 39, the negative pressure liquid suction component 2 can be restricted to different heights. When stuck in the lower layer, the rebound of the second elastic member 38 can be avoided, causing the negative pressure liquid suction component 2 to slide up and off the gun head tube 11. The push rod 310, on the one hand, can press the bent portion of the spring 39 out of the I-groove 13, and on the other hand, it can also slide down to drive the quantitative liquid suction structure 3 to slide down as a whole, so that it moves to the center and is inserted into the gun head tube 11. The operation is simple and convenient. The set limiting structure 4 can also avoid accidentally pressing the slide and causing the quantitative liquid suction structure 3 to rebound and reset, making it more stable to use.

[0070] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0071] When in use, first find the quantitative liquid aspiration structure 3 corresponding to the required capacity, press the push rod 310 inward first, make the spring piece 39 bend to disengage the I-shaped groove 13, then slide the push rod 310 downward, and push the slide rod 36 downward through the spring piece 39. At this time, the connecting rod 35 cooperates with gravity to make the bottom end of the downward-pushed quantitative tube 31 slide into the gun head tube 11 (the tapered design at the bottom end of the gun barrel 1 can guide the bottom end of the quantitative tube 31 to slide toward the center), and then, under the pressure of the slide rod 36 and the connecting rod 35, the sealing ring 34 is pressed into the gun head tube 11, and the quantitative tube 31 can be inserted, and the gun head tube 1 1 seal, push to the bottom and release the pressure on the push rod 310. At this time, the spring piece 39 rebounds and inserts into the lower horizontal section of the I-shaped groove 13 and gets stuck, thereby limiting the upward springing of the quantitative liquid aspiration structure 3. At the same time, the sliding piece at the outer end of the push rod 310 is stuck on the outside by the limiting sleeve 41. At this time, the sliding piece and the push rod 310 cannot be pressed inward. When resetting is required, the limiting sleeve 41 must be lowered to separate it from the sliding piece and the push rod 310, and then the sliding piece must be pressed to make the push rod 310 push the spring piece 39 out of the I-shaped groove 13. At this time, the second elastic member 38 can rebound and reset the quantitative tube 31.

[0072] At this time, the bottom end of the quantitative tube 31 extends out of the gun head tube 11, and the gun head can be put on to perform the liquid aspiration operation;

[0073] When aspirating liquid, first press the pressing rod 24 downward to push the first piston 23 downward. Since the gun head tube 11 at the bottom end of the gun barrel 1 is blocked by the metering tube 31, and the metering tube 31 is isolated by the second piston 32, a closed space is formed in the lower layer of the negative pressure liquid aspiration component 2. When the first piston 23 slides down, it will use air pressure to press the second piston 32. At this time, insert the gun head into the liquid again, release the pressing rod 24, and the first piston 23 will bounce up under the elastic force of the first elastic member 25, and then use the negative pressure to pull up the second piston 32, and then use the negative pressure in the metering tube 31 to absorb the air in the gun head, and then suck the liquid into the gun head, and the liquid can be transferred.

[0074] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0075] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A fast-switching three-channel quantitative pipette, comprising a barrel, and a tip tube is provided at the center of the bottom end of the barrel, characterized in that: Also includes: The negative pressure liquid suction component is fixedly connected to the middle of the barrel and is coaxially arranged with the barrel. It generates negative pressure by pressing to absorb liquid; Three sets of quantitative liquid aspiration structures are evenly distributed around the periphery of the negative pressure liquid aspiration component, and the three sets of quantitative liquid aspiration structures can absorb different capacities of liquid. By inserting the bottom ends of the different quantitative liquid aspiration structures into the gun head tube and sealing the gun head tube, when negative pressure is generated in the space below the negative pressure liquid aspiration component, liquid is aspirated through the quantitative liquid aspiration structures located in the gun head tube. In addition, a limiting structure is provided on the gun barrel to prevent the quantitative liquid aspiration structure from sliding downward and resetting due to accidental touch. Three sets of guide plates are arranged at the bottom of the inner cavity of the gun barrel and are staggered with the three sets of quantitative liquid aspiration structures, for guiding the quantitative liquid aspiration structures to move radially; The negative pressure liquid suction component includes a flange fixedly connected to the middle of the inside of the gun barrel; the quantitative liquid suction structure includes a quantitative tube, which is a needle tube type and the outer diameter of the bottom end is smaller than the inner diameter of the gun head tube. The length of the quantitative tube is greater than the length of the gun head tube, so that the bottom end of the quantitative tube can be extended from the bottom after being inserted into the gun head tube; the top of the quantitative tube is rotatably connected to a sliding rod through a connecting rod, and the sliding rod slides through the flange, and the interior of the flange is penetrated by a sealing rubber sleeve mounted on the outside of the sliding rod. The top of the sliding rod is thickened, and a second elastic member is mounted on the outside of the sliding rod and located between the thickened section and the flange for resetting the quantitative tube. The top of the sliding rod is fixed with a clamping structure that engages with the gun barrel to limit the height of the quantitative tube.

2. A fast-switching three-channel quantitative pipette according to claim 1, characterized in that: The negative pressure liquid suction component also includes: The negative pressure tube is coaxially fixed to the top of the flange, and the center of the flange is located inside the negative pressure tube and is hollowed out; a first piston, slidably connected to the interior of the negative pressure tube; A pressing rod, fixedly connected to the top of the first piston and used to press the first piston downward; The first elastic member is elastically abutted between the first piston and the flange to rebound and reset the first piston after being pressed downward.

3. The fast-switching three-channel quantitative pipette according to claim 2, characterized in that: The quantitative liquid imbibition structure further comprises: A second piston is slidably disposed inside the metering tube; The positioning ring is arranged on the inner wall of the quantitative tube and is located above the second piston. The positioning rings of the three sets of quantitative liquid suction structures have different heights, so that the second piston slides up to different distances, thereby extracting different capacities of liquid; The sealing ring is fixedly mounted on the outside of the bottom end of the quantitative tube and is used to seal the gun head tube.

4. The fast-switching three-channel quantitative pipette according to claim 3, characterized in that: The clamping structure includes a spring piece connected to the top of the sliding rod, the top of the spring piece is bent outward, and the bottom of the bent part is set as a wedge surface. A push rod is protruding in the middle of the bent part of the spring piece, and the front section of the push rod is set as a sliding structure. The sliding structure is pushed to push the spring piece to bend and slide down.

5. The fast-switching three-channel quantitative pipette according to claim 4, characterized in that: An I-shaped groove is provided on the side of the gun barrel, the horizontal section width of the I-shaped groove is adapted to the width of the shrapnel, and the vertical section width of the I-shaped groove is adapted to the push rod.

6. The fast-switching three-channel quantitative pipette according to claim 5, characterized in that: The limiting structure includes a sliding sleeve arranged on the outside of the barrel and a limiting sleeve located below the I-slot, the inner wall of the limiting sleeve and the outer wall of the barrel are respectively provided with an upper convex ring and a lower convex ring, and a third elastic member is abutted between the upper convex ring and the lower convex ring. The third elastic member pushes up the upper convex ring to allow the limiting sleeve to be inserted between the slide and the barrel to limit the slide from being pushed into the barrel.

7. The fast-switching three-channel quantitative pipette according to claim 2, characterized in that: The top end of the gun barrel is threadedly connected with a top cover, the pressing rod slides through the top cover and a pressure cap is arranged on the top end.

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