Terpenoid separated from purslane and preparation method and application thereof

Abstract

The invention belongs to the technical field of medicines, and particularly relates to terpenoids separated from purslane as well as a preparation method and application of the terpenoids. The chemical structural formula of the terpenoid is as shown in formula 1), a total extract of portulaca oleracea is firstly extracted, organic solvents with different polarities are used for extracting the total extract of the portulaca oleracea to obtain a petroleum ether layer, an ethyl acetate layer and an n-butyl alcohol layer, the ethyl acetate layer is repeatedly eluted through a silica gel column, an ODS reversed-phase column and a gel column, and the terpenoid is obtained. According to the present invention, the terpenoid is obtained through the isocratic elution of the collected same fraction through the HPLC chromatographic column and separation, and the terpenoid is obtained for the first time and shows the significant anti-inflammatory activity in vitro, such that the new choice is provided for the development of the natural anti-inflammatory drug. # imgabs0 #