Intelligent incubation system for microorganisms

Abstract

The invention provides an intelligent microbial incubation system which solves the problems that an existing intelligent microbial incubation system is unreasonable in internal structure design and cannot automatically detect the growth condition of microorganisms. The device comprises a box body, a first vertical partition plate used for dividing an inner cavity of the box body into an operation cavity and a culture cavity is arranged in the box body, and a sample inlet and outlet isolation conveying assembly used for conveying a loader between the operation cavity and the culture cavity is arranged on the first vertical partition plate. A heating assembly, a bearing assembly for placing a loader and a first transfer assembly for transferring the loader between the bearing assembly and the sample inlet and outlet isolated conveying assembly are arranged in the culture cavity, and a transfer box, a second transfer assembly for transferring the loader between the transfer box and the sample inlet and outlet isolated conveying assembly and a detection bin are arranged in the operation cavity; and a detection assembly for detecting the growth condition of microorganisms in the loader is arranged in the detection bin. The device has the advantages of reasonable internal structural design, large storage capacity, capability of intelligently detecting the growth condition of microorganisms and the like.

Description

Technical Field

[0001] The invention belongs to the technical field of microbial cultivation and relates to a microbial intelligent incubation system. Background Art

[0002] Microbial incubator is a common laboratory equipment, which is mainly used to provide a stable temperature environment to simulate the ideal conditions for microbial growth, thereby promoting the cultivation and reproduction of various microorganisms such as bacteria, yeast, and mold. It can be used for microbial culture experiments in clinical medicine, scientific research, quality control, teaching experiments, and industrial production processes. The demand for incubator volume varies greatly for laboratories or medical institutions of different sizes. Small laboratories may require a compact design due to limited space, while large laboratories may require large-volume incubators to meet batch sample culture.

[0003] For use scenarios such as hospitals, multiple samples are usually processed at the same time, so large-capacity incubators are needed to meet daily inspection needs. Currently, most large-volume incubators are of integral structure, which is not convenient for transportation, installation, and later mobile maintenance. In addition, existing incubators fail to make reasonable use of internal space, resulting in small loading capacity. In order to understand the growth of microorganisms, it is necessary to manually check the loaders one by one, which is not only inefficient, but also affects the culture environment of the entire system. Summary of the invention

[0004] The purpose of the present invention is to solve the above problems in the prior art and to propose a more rationally designed microbial intelligent incubation system.

[0005] The purpose of the present invention can be achieved by the following technical solutions:

[0006] A microbial intelligent incubation system comprises a box body, wherein the box body is provided with a first vertical partition for dividing the inner cavity of the box body into an operating cavity and a culture cavity, the first vertical partition is provided with an inlet and outlet sample isolation conveying component for conveying a loader between the operating cavity and the culture cavity, the culture cavity is provided with a heating component, a bearing component for placing the loader and a first transfer component for transferring the loader between the bearing component and the inlet and outlet sample isolation conveying component, the operating cavity is provided with a transfer box, a second transfer component for transferring the loader between the transfer box and the inlet and outlet sample isolation conveying component and a detection chamber, and the detection chamber is provided with a detection component for detecting the growth status of microorganisms in the loader.

[0007] When in use, the transfer box for loading with the loader is placed in the operation chamber, and the loader in the transfer box is moved to the sample inlet and outlet isolation conveying component through the second transfer component, and the loader in the sample inlet and outlet isolation conveying component is transferred to the bearing component through the first transfer component, and the microorganisms in the loader are incubated under the action of the heating component. After a period of incubation, the loader on the bearing component can be moved to the detection chamber through the first transfer component, and the growth status of the microorganisms in the loader can be detected by the detection component. After the detection is completed, the loader is transported back to the bearing component.

[0008] The loader that meets the requirements for microbial growth is transferred to the transfer box for discharge under the action of the first transfer component, the inlet and outlet sample isolation conveying component and the second transfer component.

[0009] In the above-mentioned microbial intelligent incubation system, a filter chamber is provided on the top of the operation chamber, a filter is provided in the filter chamber, an inlet of the filter is connected to the upper part of the culture chamber, and an outlet of the filter is connected to the lower part of the culture chamber through a pipeline, and a circulating fan is provided in series on the pipeline.

[0010] The circulating fan works to draw the gas in the culture chamber into the filter. After the filter filters out harmful substances such as aerosols in the gas, the gas flows back to the culture chamber through the pipeline to prevent the gas environment in the culture chamber from being polluted.

[0011] In the above-mentioned microbial intelligent incubation system, a transverse partition is provided at the lower part of the culture chamber, a protective chamber is provided below the transverse partition, the outlet of the above-mentioned pipeline is connected to the protective chamber, and a plurality of equal flow holes are provided on the transverse partition.

[0012] By arranging equal flow holes on the transverse partition, the purified gas can flow back into the culture chamber evenly, thus ensuring the balance of the culture environment.

[0013] In the above-mentioned microbial intelligent incubation system, an air inlet bin is provided on the side of the protection cavity, and a plurality of evenly distributed through holes for communicating with the protection cavity are provided on the side of the air inlet bin facing the protection cavity. The outlet of the above-mentioned pipeline is connected to the air inlet bin, and a heating element for heating is provided on the air inlet bin. The purified gas can be preheated so that the gas reaches the temperature required by the microorganism in advance to avoid affecting the culture environment. The heating element is in the shape of a plate and can be attached to the outer side of the air inlet bin.

[0014] In the above-mentioned microbial intelligent incubation system, a second vertical partition is provided in the box body, the bearing assembly and the first transfer assembly are located on one side of the second vertical partition, and the air intake bin, pipeline and circulating fan are located on the other side of the second vertical partition.

[0015] The second vertical partition divides the culture chamber into two parts, which are not connected.

[0016] The heating component is at least one heating plate attached to the side of the second vertical partition away from the culture chamber, and at least one heating plate is also attached to the surface of the culture chamber opposite to the second vertical partition to keep the culture chamber in a suitable temperature range.

[0017] In the above-mentioned microbial intelligent incubation system, an opening connected to the culture chamber is provided on the side of the detection chamber, a first cover plate for covering the opening is provided at the opening, a first driving member for opening / closing the first cover plate is provided in the detection chamber, and a first negative pressure adsorption hole connected to the inlet of the filter is provided on the detection chamber.

[0018] The first cover separates the detection chamber from the culture chamber, and absorbs harmful substances such as aerosols generated when the cover is opened through the first negative pressure adsorption hole, thereby preventing the aerosols generated by opening the cover of the loader from entering the culture chamber and preventing the culture environment in the culture chamber from being damaged.

[0019] In the above-mentioned microbial intelligent incubation system, the detection component includes a first tray driven by a first linear module arranged in the detection chamber, an opening module and a photo chamber arranged in sequence along the movement path of the first tray, a camera module is provided on the top of the photo chamber, and a lighting lamp for illumination is provided on the side of the photo chamber.

[0020] The cover opening module and the photographing chamber are located above the movement path of the first tray, and are used to open and close the cover of the loader and take photos of the microorganisms in the loader respectively, and the lighting lamp provides lighting for taking photos. The cover opening module includes a second linear module arranged vertically and a first clamping jaw driven by a first electric finger arranged on the second linear module, and the first clamping jaw can move up and down along the second linear module, and the first clamping jaw can clamp the upper cover of the loader.

[0021] In the above-mentioned microbial intelligent incubation system, a movable cover is slidably matched with one end of the photographing chamber away from the cover module, and guide grooves are respectively provided on the left and right sides of the movable cover. A guide bar is provided on the photographing chamber and slidably matched with the guide groove. A locking nut is threadedly connected on the guide bar for tightening the movable cover when the movable cover is moved into place, and the lighting lamp is arranged on the inner side of the movable cover.

[0022] The thickness of the guide strip is smaller than that of the movable cover, so that the locking nut can be used to lock the movable cover in place. When the movable cover moves, the illuminating lamp can be driven to move together, and the position of the illuminating lamp can be adjusted to meet the lighting needs when taking photos.

[0023] In the above-mentioned microbial intelligent incubation system, at least one adsorption seat located on the side of the cover opening module is provided in the detection chamber, a second negative pressure adsorption hole is provided on the side of the adsorption seat facing the cover opening module, and a third negative pressure adsorption hole is provided on the photographing chamber, and the second negative pressure adsorption hole and the third negative pressure adsorption hole are respectively connected to the inlet of the filter.

[0024] When the cover is opened, harmful substances such as aerosols are sucked away through the second negative pressure adsorption hole, and harmful substances such as aerosols in the photo chamber can be sucked away by the third negative pressure adsorption hole.

[0025] In the above-mentioned microbial intelligent incubation system, the first transfer component includes four third linear modules respectively arranged at the four corners of the culture chamber, a fourth linear module driven by the third linear module and arranged horizontally, a fifth linear module driven by the fourth linear module and arranged horizontally, a rotating module arranged on the fifth linear module, and a second clamp driven by a second electric finger arranged on the rotating module, and the fourth linear module is perpendicular to the fifth linear module.

[0026] The four third linear modules move synchronously, driving the fourth linear module to move up and down. When the fourth linear module moves, it drives the fifth linear module to move horizontally. When the fifth linear module moves, it drives the rotary module to move horizontally. The rotary module drives the second electric finger to rotate. The second electric finger drives the second clamp to open and close, thus clamping the loader. Under the action of the first transfer component, the loader can achieve lifting, translation and rotation.

[0027] In the above-mentioned microbial intelligent incubation system, the four third linear modules are driven by the same motor, and the motor for driving the third linear modules is located in the protective cavity.

[0028] The motor for driving the third linear module is protected by a transverse partition.

[0029] In the above-mentioned microbial intelligent incubation system, the bearing assembly is multiple and evenly arranged on two opposite sides of the culture chamber along the up and down direction of the box; the bearing assembly includes a support plate, a partition frame arranged on the support plate, and a mounting frame arranged on the partition frame, the partition frame is provided with a plurality of placement cavities adapted to the loader, the bottom of the placement cavity is a support plate, and the support plate is provided with a plurality of clearance openings arranged one-to-one with the placement cavities. The mounting frame is used to install the bearing assembly to two opposite sides of the culture chamber, the support plate supports the loader, the partition frame limits the loader, and the clearance opening provides clearance space for the movement of the second clamp, so as to facilitate the second clamp to take and place the loader.

[0030] In the above-mentioned microbial intelligent incubation system, the sample inlet and outlet isolation and conveying components include a sample inlet isolation and conveying component and a sample outlet isolation and conveying component, and the sample inlet isolation and conveying component and the sample outlet isolation and conveying component correspond to different second transfer components and transfer boxes respectively.

[0031] The efficiency can be improved by separately arranging the sample inlet isolation conveying component and the sample outlet isolation conveying component and corresponding to different second transfer components and transfer boxes.

[0032] In the above-mentioned microbial intelligent incubation system, the sampling isolation and conveying component includes a sampling chamber with an inlet and an outlet, a first conveying track arranged outside the inlet of the sampling chamber, and a second tray arranged in the sampling chamber and driven by a sixth linear module. The inlet and outlet of the sampling chamber are arranged opposite to each other, the inlet of the sampling chamber is provided with a second cover plate, the outlet of the sampling chamber is provided with a third cover plate, a second driving member for opening / closing the second cover plate and a third driving member for opening / closing the third cover plate are provided in the sampling chamber, and the sampling chamber is also provided with a pushing member for pushing the loader on the first conveying track into the sampling chamber, and the pushing member is driven by the seventh linear module.

[0033] The upper surface of the second tray is flush with the upper surface of the first conveying track. When the loader enters the box, the loader is sent to the first conveying track by the second transfer assembly. The first conveying track conveys the loader to the entrance of the sample injection bin. When the loader is in place, the second driving member drives the second cover to open, and the second tray moves to the entrance under the action of the sixth linear module. Then, the pushing member pushes the loader on the first conveying track through the entrance to the second tray under the action of the seventh linear module. Then, the sixth linear module drives the second tray to move into the sample injection bin, and the second cover closes the entrance under the action of the second driving member.

[0034] Then the third driving member opens the third cover, the second tray extends from the outlet under the action of the sixth linear module, and transports the loader to the culture chamber through the outlet, and the first transport component in the culture chamber transports the loader on the second tray to the carrying component.

[0035] In the above-mentioned microbial intelligent incubation system, the sample isolation and conveying component includes a sample bin with an inlet and an outlet, a second conveying track arranged outside the sample bin outlet, and a third tray arranged in the sample bin and driven by an eighth linear module. The inlet and outlet of the sample bin are arranged opposite to each other, the inlet of the sample bin is provided with a fourth cover plate, the outlet of the sample bin is provided with a fifth cover plate, a fourth driving member for opening / closing the fourth cover plate and a fifth driving member for opening / closing the fifth cover plate are provided in the sample bin, and a hook and pull member for hooking the loader on the third tray to the second conveying track is also provided on the sample bin, and the hook and pull member is driven by the ninth linear module.

[0036] When the cultured loader needs to be taken out of the box, the first transfer component transports the loader on the carrying component to the entrance of the sample output bin, the fourth driving member opens the fourth cover, and the third tray extends out from the entrance of the sample output bin under the action of the eighth linear module. The first transfer component places the loader on the third tray, and then the third tray enters the sample output bin and moves to the middle of the sample output bin under the action of the eighth linear module. The fourth driving member causes the fourth cover to close the entrance of the sample output bin, and then the fifth driving member opens the fifth cover. The third tray moves to the exit of the sample output bin under the action of the eighth linear module, and the hook and pull member extends into and hooks the loader through the exit of the sample output bin under the action of the ninth linear module, and then hooks the loader onto the second conveying track. The fifth driving member closes the fifth cover, and the loader is sent to the end by the second conveying track. The second transfer component corresponding to the sample output isolation conveying component transfers the loader to the transfer box for discharge.

[0037] In the above-mentioned microbial intelligent incubation system, a groove is provided at the end of the hook-pull member, and a blocking block is rotatably provided in the groove. When the hook-pull member extends into the sample outlet bin, the blocking block swings toward the groove. A blocking surface is provided in the groove. When the hook-pull member moves outward from the sample outlet bin, the upper end of the blocking block abuts against the blocking surface.

[0038] When the hook piece extends into the sample outlet, the slot provides space for the blocking block to enter the slot, preventing the blocking block from pushing the loader below. After the blocking block passes over the loader, it resets under the action of its own gravity. At this time, the lower end of the blocking block is lower than the upper surface of the loader. When the hook piece moves outward, the blocking block can hook the loader out.

[0039] In the above-mentioned microbial intelligent incubation system, the second transfer component includes a vertically arranged tenth linear module, an eleventh linear module arranged on the tenth linear module and driven by the tenth linear module, and a negative pressure suction cup arranged on the eleventh linear module and driven by the eleventh linear module, and the eleventh linear module extends horizontally.

[0040] In the above-mentioned microbial intelligent incubation system, the box body is provided with a vent hole for communicating with the culture chamber, and a vent valve is provided at the vent hole. The vent hole can provide a gas environment for the culture chamber, and different culture environments can be configured through electronic control.

[0041] The above-mentioned microbial intelligent incubation system also includes a control system for controlling the actions of various components in the box. The camera module is connected to the control system via a connector, and the connector is used to transmit the image signal captured by the camera module to the control system.

[0042] The control system is connected to an external display screen and an AI data model to store and analyze pictures taken by the camera module and build an image database to facilitate full-process tracing and viewing of historical growth conditions. Because photos are stored, there is no need to manually look through the loader when the growth status needs to be understood, and it does not affect the entire cultivation environment.

[0043] The control system can take regular photos of microorganisms in the loader that have been cultured for a certain period of time according to the set time, obtain the photos, and perform AI analysis to determine the growth of the microorganisms. If it is found that the growth of microorganisms that have not reached the culture time meets the requirements, the control system controls the corresponding components to send the corresponding loader to the transfer box for discharging, shortening the culture time and process. The control system can classify and place loaders with similar microbial growth based on the data analyzed by the AI ​​data model.

[0044] In the above-mentioned microbial intelligent incubation system, a temperature sensor, a humidity sensor and a gas concentration sensor are provided in the culture chamber, and the signal output ends of the temperature sensor, humidity sensor and gas concentration sensor are respectively connected to the input ends of the control system. The control system controls the corresponding components according to the detected data to achieve the control of temperature, humidity and gas concentration. An alarm device connected to the control system is also provided on the box body, and an alarm can be sounded through the alarm device when a system failure occurs.

[0045] There are at least two instant stop switches on the box to stop the system in an emergency.

[0046] Compared with the prior art, the present microbial intelligent incubation system has the following advantages: there are multiple bearing components and they are evenly arranged on two opposite sides of the culture chamber along the up and down directions of the box body, which can maximize the use of space and improve the internal space utilization rate and storage capacity; the box body is provided with docking interfaces at both ends of the first conveying track and the second conveying track, and multiple intelligent incubation systems can be connected in series according to actual use needs, which is convenient for transportation and assembly, can meet the incubation needs of different microorganisms, and has a wide range of applications. Multiple intelligent incubation systems connected in series can be controlled by the same control system; the sample inlet, sample outlet and camera chambers are all isolation chambers, which can reduce the airflow exchange between them and the culture chamber to avoid affecting the culture environment. At the same time, filters are provided to filter out harmful substances in the culture chamber to avoid poor infection; a control system is provided, and the control system is connected to the AI ​​data model to monitor and analyze the growth status of microorganisms in the loader in real time. BRIEF DESCRIPTION OF THE DRAWINGS

[0047] Figure 1 It is a structural schematic diagram of the microbial intelligent incubation system provided by the present invention.

[0048] Figure 2 is Figure 1A structural schematic diagram with a small portion of the right side panel hidden.

[0049] Figure 3 is Figure 2 The structural diagram is a diagram in which a small part of the right side panel and the first box door are hidden.

[0050] Figure 4 It is a structural schematic diagram of the microbial intelligent incubation system with the right side panel hidden.

[0051] Figure 5 It is a cross-sectional view of the microbial intelligent incubation system along the front-to-back direction.

[0052] Figure 6 It is a cross-sectional view of the microbial intelligent incubation system along the left and right directions.

[0053] Figure 7 It is a schematic diagram of the structure of the first transfer component.

[0054] Figure 8 It is a structural diagram of the detection chamber.

[0055] Fig. 9 It is a schematic diagram of the internal structure of the detection chamber.

[0056] Fig.10 It is a structural schematic diagram of the sample injection isolation and delivery assembly.

[0057] Fig.11 is Fig.10 The structural diagram is shown in FIG. 1 with the sample injection chamber hidden.

[0058] Fig.12 It is a schematic diagram of the structure of the sample isolation and conveying assembly.

[0059] Fig.13 is Fig.12 The structural diagram of the sample chamber is hidden on the basis of FIG.

[0060] Fig.14 It is a cross-sectional view of the hook and pull piece passing through the blocking block.

[0061] Fig.15 It is a schematic diagram of the structure of the second transfer component.

[0062] Fig.16 It is a structural schematic diagram of a single load-bearing component.

[0063] In the figure, a, loader; 1, box body; 2, first vertical partition; 3, transfer box; 4, detection chamber; 5, filter chamber; 6, filter; 7, pipeline; 8, circulation fan; 9, horizontal partition; 10, protection chamber; 11, flow equalization hole; 12, air intake chamber; 13, through hole; 14, heating element; 15, second vertical partition; 16, heating plate; 17, opening; 18, first cover plate; 19, first driving element; 20, first negative pressure adsorption hole; 21, first linear module; 22, first tray; 23, cover opening module; 24, photo chamber; 25, camera module; 26, lighting lamp; 27, movable cover; 28, guide groove; 29, guide strip; 30, adsorption seat; 31, second negative pressure adsorption hole; 32, third negative pressure adsorption hole; 33, third linear module; 34, fourth linear module; 35 , the fifth linear module; 36, the rotating module; 37, the support plate; 38, the partition frame; 39, the mounting frame; 40, the clearance port; 41, the sample loading chamber; 42, the first conveying track; 43, the sixth linear module; 44, the second tray; 45, the second cover plate; 46, the third cover plate; 47, the second driving member; 48, the third driving member; 49, the pushing member; 50, the seventh linear module; 51, the sample output chamber; 52, the second conveying track; 53, the eighth linear module; 54, the third tray; 55, the fourth cover plate; 56, the fifth cover plate; 57, the fourth driving member; 58, the fifth driving member; 59, the hook and pull member; 60, the ninth linear module; 61, the slot; 62, the blocking block; 63, the blocking surface; 64, the tenth linear module; 65, the eleventh linear module; 66, the negative pressure suction cup; 67, the vent. DETAILED DESCRIPTION

[0064] The following are specific embodiments of the present invention and the accompanying drawings to further describe the technical solution of the present invention, but the present invention is not limited to these embodiments.

[0065] like Figure 1 The microbial intelligent incubation system shown in the figure comprises a rectangular box 1, wherein the width of the box 1 in the front-to-back direction is greater than the thickness of the box 1 in the left-to-right direction. Figure 3 and Figure 5 As shown, a first vertical partition 2 is provided in the box body 1 for dividing the inner cavity of the box body 1 into an operation cavity and a culture cavity. The first vertical partition 2 is parallel to the front and rear sides of the box body 1 .

[0066] In this embodiment, the operation chamber is located at the front side, and the culture chamber is located at the rear side. A front door that can be opened and closed is provided on the front side of the box body 1. After opening the front door, the components in the operation chamber can be operated. A rear door that can be opened and closed is provided on the rear side of the box body 1. The rear door is normally closed. When necessary, the rear door can be opened to install, maintain, repair or replace the components in the culture chamber. For easy observation, a transparent observation window is provided on the rear door. Windows are provided on the left and right sides of the operation chamber, and multiple boxes 1 can be connected in series. The windows serve as connecting channels for conveying tracks.

[0067] like Figure 6 As shown, a transverse partition 9 is provided at the lower part of the culture bin, and a protective cavity 10 is provided below the transverse partition 9. A plurality of equal flow holes 11 are provided on the transverse partition 9. An air inlet bin 12 is provided on the right side of the protective cavity 10. A plurality of evenly distributed through holes 13 for communicating with the protective cavity 10 are provided on the side of the air inlet bin 12 facing the protective cavity 10. A heating element 14 for heating is attached to the outer surface of the air inlet bin 12. The heating element 14 is in the shape of a plate and can preheat the purified gas so that the gas reaches the temperature required by the microorganisms in advance to avoid affecting the culture environment.

[0068] like Figure 6 As shown, a second vertical partition 15 is provided in the box body 1, the bearing assembly and the first transfer assembly are located on the left side of the second vertical partition 15, the air inlet bin 12, the pipeline 7 and the circulating fan 8 are located on the right side of the second vertical partition 15, and the second vertical partition 15 divides the culture chamber into two parts, which are not connected.

[0069] like Figure 6 As shown, the culture chamber is provided with a heating component, a carrying component for placing the loader a, and a first transport component for transporting the loader a between the carrying component and the sample inlet and outlet isolation transport component. There are multiple carrying components and they are evenly arranged on the left and right sides of the culture chamber along the vertical direction of the box body 1.

[0070] like Figure 1 As shown, a vent hole 67 for communicating with the culture chamber is provided on the box body 1, and a vent valve is provided at the vent hole 67. The vent hole 67 can provide a gas environment for the culture chamber, and different culture environments can be configured through electronic control.

[0071] like Fig.16As shown, the bearing assembly includes a support plate 37, a partition frame 38 disposed on the support plate 37, and a mounting frame 39 disposed on the partition frame 38. The partition frame 38 is provided with a plurality of placement cavities adapted to the loader a. The bottom of the placement cavity is the support plate 37. The support plate 37 is provided with a plurality of clearance openings 40 corresponding to the placement cavities. The mounting frame 39 is used to mount the bearing assembly to two opposite sides of the culture chamber. The support plate 37 supports the loader a, the partition frame 38 limits the loader a, and the clearance openings 40 provide clearance space for the movement of the second gripper, so as to facilitate the second gripper to take and place the loader a.

[0072] In this embodiment, Figure 4 As shown, the heating assembly is a plurality of heating plates 16 attached to the side of the second vertical partition 15 away from the culture chamber, and a plurality of heating plates 16 are also attached to the surface of the right side of the box body 1 on the side opposite to the second vertical partition 15 and located on the inner side of the box body shell, for keeping the culture chamber within a suitable temperature range.

[0073] like Figure 7 As shown, the first transport component includes four third linear modules 33 respectively arranged at the four corners of the culture chamber, a fourth linear module 34 driven by the third linear module 33 and arranged horizontally, a fifth linear module 35 driven by the fourth linear module 34 and arranged horizontally, a rotating module 36 arranged on the fifth linear module 35 and a second clamp driven by a second electric finger arranged on the rotating module 36, and the fourth linear module 34 is perpendicular to the fifth linear module 35.

[0074] The four third linear modules 33 act synchronously, driving the fourth linear module 34 to move up and down. When the fourth linear module 34 acts, it drives the fifth linear module 35 to move horizontally. When the fifth linear module 35 acts, it drives the rotating module 36 to move horizontally. The rotating module 36 drives the second electric finger to rotate. The second electric finger drives the second clamping claw to open and close, thereby clamping the loader A. Under the action of the first transfer component, the loader A can achieve lifting, translation and rotation.

[0075] The four third linear modules 33 are driven by the same motor. Figure 5 and Figure 6 As shown, the motor for driving the third linear module 33 is located in the protection cavity 10 , and the motor for driving the third linear module 33 is protected by the transverse partition plate 9 .

[0076] like Figure 5 As shown, an independent filtering chamber 5 is provided above the operation chamber, and a filter 6 is provided in the filtering chamber 5. The inlet of the filter 6 is connected to the upper part of the culture chamber, as shown in FIG. Figure 2 and Figure 3 As shown, the outlet of the filter 6 is connected to the air inlet bin 12 through the pipeline 7, and a circulation fan 8 is connected in series to the pipeline 7.

[0077] The circulating fan 8 works to draw the gas in the culture chamber into the filter 6. After the filter 6 filters out harmful substances such as aerosols in the gas, the gas flows back to the culture chamber through the pipeline 7 to prevent the gas environment in the culture chamber from being polluted.

[0078] like Figure 3-5 As shown, a transfer box 3, a second transfer component for transferring loader a between the transfer box 3 and the sample inlet and outlet isolation conveying component, and a detection chamber 4 are provided in the operating chamber. The detection chamber 4 is provided with a detection component for detecting the growth status of microorganisms in the loader a.

[0079] When in use, the transfer box 3 for loading materials equipped with loader a is placed in the operating chamber, the loader a in the transfer box 3 is moved to the input and output sample isolation and conveying component through the second transfer component, and the loader a in the input and output sample isolation and conveying component is transferred to the carrying component through the first transfer component, and the microorganisms in the loader a are incubated under the action of the heating component.

[0080] After a period of incubation, the loader a on the carrying component can be moved to the detection chamber 4 through the first transport component, and the growth status of microorganisms in the loader a can be detected by the detection component. After the detection is completed, the loader a is transported back to the carrying component.

[0081] The loader a that meets the requirements for microbial growth is transferred to the transfer box 3 for discharging under the action of the first transfer component, the inlet and outlet sample isolation conveying component and the second transfer component.

[0082] like Figure 8 and Fig. 9 As shown, the side of the detection chamber 4 is provided with an opening 17 connected to the culture chamber, and a first cover plate 18 for covering the opening 17 is provided at the opening 17. A first driving member 19 for opening / closing the first cover plate 18 is provided in the detection chamber 4, and a first negative pressure adsorption hole 20 connected to the inlet of the filter 6 is provided on the detection chamber 4.

[0083] The first cover plate 18 separates the detection chamber 4 from the culture chamber, and absorbs harmful substances such as aerosols generated when the cover is opened through the first negative pressure adsorption hole 20, thereby preventing the aerosols generated by opening the cover of the loader a from entering the culture chamber and preventing the culture environment in the culture chamber from being damaged.

[0084] like Fig. 9 As shown, the detection component includes a first tray 22 driven by a first linear module 21 arranged in the detection chamber 4, an opening module 23 and a photo chamber 24 arranged in sequence along the movement path of the first tray 22, a camera module 25 is provided on the top of the photo chamber 24, and a lighting lamp 26 for lighting is provided on the side of the photo chamber 24.

[0085] The cover opening module 23 and the photographing chamber 24 are located above the movement path of the first tray 22, and are used to open and close the cover of the loader a and photograph the microorganisms in the loader a, respectively. The lighting lamp 26 provides lighting for photographing. The cover opening module 23 includes a second linear module arranged vertically and a first clamping jaw driven by a first electric finger arranged on the second linear module. The first clamping jaw can move up and down along the second linear module, and the first clamping jaw can clamp the upper cover of the loader a.

[0086] like Fig. 9 As shown, one end of the photographing chamber 24 away from the cover module 23 is slidably matched with a movable cover 27, and guide grooves 28 are respectively provided on the left and right sides of the movable cover 27. The photographing chamber 24 is provided with a guide bar 29 slidably matched with the guide groove 28, and a locking nut for tightening the movable cover 27 when the movable cover 27 is moved into place is threadedly connected to the guide bar 29. The lighting lamp 26 is arranged on the inner side of the movable cover 27.

[0087] The thickness of the guide bar 29 is less than that of the movable cover 27, so that the locking nut can be used to lock the movable cover 27. When the movable cover 27 moves, the illuminating lamp 26 can be driven to move together, and the position of the illuminating lamp 26 can be adjusted to meet the lighting requirements when taking pictures.

[0088] like Fig. 9 As shown, two adsorption seats 30 are provided in the detection chamber 4 and are located on the side of the cover opening module 23. A second negative pressure adsorption hole 31 is provided on the side of the adsorption seat 30 facing the cover opening module 23. A third negative pressure adsorption hole 32 is provided on the photographing chamber 24. The second negative pressure adsorption hole 31 and the third negative pressure adsorption hole 32 are respectively connected to the inlet of the filter 6. When the cover is opened, harmful substances such as aerosols are sucked away through the second negative pressure adsorption hole 31, and harmful substances such as aerosols in the photographing chamber 24 can be sucked away through the third negative pressure adsorption hole 32.

[0089] like Figure 5 As shown, a sample inlet and outlet isolation conveying assembly for conveying the loader a between the operation chamber and the culture chamber is provided on the first vertical partition 2. Specifically, the sample inlet and outlet isolation conveying assembly includes a sample inlet isolation conveying assembly and a sample outlet isolation conveying assembly, and the sample inlet isolation conveying assembly and the sample outlet isolation conveying assembly correspond to different second transport assemblies and transfer boxes 3, respectively.

[0090] like Fig.10 and Fig.11As shown, the sample injection isolation and conveying assembly includes a sample injection chamber 41 with an inlet and an outlet, a first conveying track 42 arranged outside the inlet of the sample injection chamber 41, and a second tray 44 arranged in the sample injection chamber 41 and driven by a sixth linear module 43. The inlet and outlet of the sample injection chamber 41 are arranged opposite to each other, the inlet of the sample injection chamber 41 is provided with a second cover plate 45, and the outlet of the sample injection chamber 41 is provided with a third cover plate 46. A second driving member 47 for opening / closing the second cover plate 45 and a third driving member 48 for opening / closing the third cover plate 46 are provided in the sample injection chamber 41. The sample injection chamber 41 is also provided with a pushing member 49 for pushing the loader a on the first conveying track 42 into the sample injection chamber 41, and the pushing member 49 is driven by the seventh linear module 50.

[0091] The upper surface of the second tray 44 is flush with the upper surface of the first conveying track 42. When loader a enters the box, loader a is sent to the first conveying track 42 by the second transfer assembly. The first conveying track 42 conveys loader a to the entrance of the sample injection chamber 41. When loader a is in place, the second driving member 47 drives the second cover 45 to open, and the second tray 44 moves to the entrance under the action of the sixth linear module 43. Then, the pushing member 49 pushes the loader a located on the first conveying track 42 to the second tray 44 through the entrance under the action of the seventh linear module 50. Then, the sixth linear module 43 drives the second tray 44 to move into the sample injection chamber 41, and the second cover 45 closes the entrance under the action of the second driving member 47.

[0092] Then the third driving member 48 opens the third cover 46, and the second tray 44 extends out from the outlet under the action of the sixth linear module 43, and transports the loader a to the culture chamber through the outlet, and the first transport component in the culture chamber transports the loader a on the second tray 44 to the carrying component.

[0093] like Fig.12 and Fig.13 As shown, the sample isolation and conveying assembly includes a sample bin 51 with an inlet and an outlet, a second conveying track 52 arranged outside the outlet of the sample bin 51, and a third tray 54 arranged in the sample bin 51 and driven by an eighth linear module 53. The inlet and outlet of the sample bin 51 are arranged opposite to each other, the inlet of the sample bin 51 is provided with a fourth cover plate 55, the outlet of the sample bin 51 is provided with a fifth cover plate 56, a fourth driving member 57 for opening / closing the fourth cover plate 55 and a fifth driving member 58 for opening / closing the fifth cover plate 56 are provided in the sample bin 51, and a hooking member 59 for hooking the loader a on the third tray 54 to the second conveying track 52 is also provided on the sample bin 51, and the hooking member 59 is driven by the ninth linear module 60.

[0094] When the cultured loader a needs to be taken out of the box, the first transfer component transports the loader a on the carrying component to the entrance of the sample output bin 51, the fourth driving member 57 opens the fourth cover 55, and the third tray 54 extends out from the entrance of the sample output bin 51 under the action of the eighth linear module 53. The first transfer component places the loader a on the third tray 54, and then the third tray 54 enters the sample output bin 51 under the action of the eighth linear module 53 and moves to the middle part of the sample output bin 51. The fourth driving member 57 causes the fourth cover 55 to close the entrance of the sample output bin 51, and the fifth driving member 58 opens the fifth cover 56. The third tray 54 moves to the exit of the sample output bin 51 under the action of the eighth linear module 53.

[0095] Under the action of the ninth linear module 60, the hook and pull member 59 extends into the outlet of the sample discharge bin 51 and hooks the loader a, and then hooks the loader a onto the second conveying track 52. The fifth driving member 58 closes the fifth cover plate 56, and the loader a is transported to the end by the second conveying track 52. The second transfer assembly corresponding to the sample discharge isolation conveying assembly transfers the loader a to the transfer box 3 for discharge.

[0096] like Fig.14 As shown, a slot 61 is provided at the end of the hook member 59, and a blocking block 62 is rotatably provided in the slot 61. When the hook member 59 extends into the sample outlet chamber 51, the blocking block 62 swings toward the slot 61. A blocking surface 63 is provided in the slot 61. When the hook member 59 moves outward from the sample outlet chamber 51, the upper end of the blocking block 62 abuts against the blocking surface 63.

[0097] When the hook member 59 extends into the sample outlet chamber 51, the slot 61 provides a space for the blocking block 62 to enter the slot 61, preventing the blocking block 62 from pushing the loader a below. After the blocking block 62 passes over the loader a, it returns to its original position under the action of its own gravity. At this time, the lower end of the blocking block 62 is lower than the upper surface of the loader a. When the hook member 59 moves outward, the blocking block 62 can hook out the loader a.

[0098] like Fig.15 As shown, the second transfer assembly includes a tenth linear module 64 arranged vertically, an eleventh linear module 65 arranged on the tenth linear module 64 and driven by the tenth linear module 64, and a negative pressure suction cup 66 arranged on the eleventh linear module 65 and driven by the eleventh linear module 65, and the eleventh linear module 65 extends horizontally.

[0099] In this embodiment, the first driving member, the second driving member, the third driving member, the fourth driving member, and the fifth driving member are all pull rod motors, and both ends of the pull rod motors are hinged to each bin body and each cover plate.

[0100] The microbial intelligent incubation system also includes a control system for controlling the actions of various components in the box 1. The camera module 25 is connected to the control system via a connector, and the connector is used to transmit the image signal captured by the camera module 25 to the control system.

[0101] The control system is connected to an external display screen and an AI data model to store and analyze the pictures taken by the camera module 25 and establish an image database to facilitate the tracing of the entire process and the viewing of historical growth conditions. Since the pictures are stored, when the growth conditions need to be understood, there is no need to manually look through the loader a, and it does not affect the entire cultivation environment.

[0102] The control system can take regular photos of the microorganisms in the loader a that have been cultured for a certain period of time according to the set time, obtain the photographed pictures, and perform AI analysis to determine the growth of the microorganisms. If it is found that the growth of the microorganisms that have not reached the culture time meets the requirements, the control system controls the corresponding components to send the corresponding loader a to the transfer box 3 for discharging, shortening the culture time and process. The control system can classify and place the loaders a with similar microbial growth based on the data analyzed by the AI ​​data model.

[0103] A temperature sensor, a humidity sensor and a gas concentration sensor are arranged in the culture chamber, and the signal output ends of the temperature sensor, the humidity sensor and the gas concentration sensor are respectively connected to the input ends of the control system. The control system controls the corresponding components according to the detected data to realize the control of temperature, humidity and gas (such as carbon dioxide, nitrogen or air, etc.) concentration.

[0104] An alarm device connected to the control system is also provided on the housing 1, and an alarm can be generated through the alarm device when the system fails. At least two stop switches are provided on the housing 1, and the system can be stopped in an emergency.

[0105] When in use, the transfer box 3 for loading with the loader a is placed in the operating chamber, and the second transfer component grabs the loader a through the suction cup 66 and places it on the first conveying track. The first conveying track conveys the loader to the entrance of the sample injection chamber. When the loader is in place, the second driving member drives the second cover to open, and the second tray moves to the entrance under the action of the sixth linear module. Then, the pushing member pushes the loader located on the first conveying track through the entrance to the second tray under the action of the seventh linear module. Then, the sixth linear module drives the second tray to move into the sample injection chamber. The second cover closes the entrance under the action of the second driving member. Then, the third driving member opens the third cover. The second tray extends from the outlet under the action of the sixth linear module, and transports the loader to the culture chamber through the outlet. The first transfer component in the culture chamber transfers the loader on the second tray to the carrying component, and the microorganisms in the loader are incubated in the culture chamber.

[0106] When taking pictures at a fixed time, the loader in the culture chamber is moved to the opening 17 of the detection chamber 4 by the first transport component, the first cover 18 is opened, the loader is received by the first tray 22, the first cover 18 is closed, and the cover opening module opens the cover of the loader. The loader after opening is sent to the photo chamber, and the microorganisms after opening are photographed by the camera module 25, and the data is transmitted to the control system. Then the cover opening module closes the cover of the loader, and the loader is sent back to the supporting component of the culture chamber.

[0107] When exiting the warehouse, the first transfer component transports the loader a on the carrying component to the entrance of the sample warehouse 51, the fourth driving member 57 opens the fourth cover 55, and the third tray 54 extends out from the entrance of the sample warehouse 51 under the action of the eighth linear module 53. The first transfer component places the loader a on the third tray 54, and then the third tray 54 enters the sample warehouse 51 under the action of the eighth linear module 53. The fourth driving member 57 causes the fourth cover 55 to close the entrance of the sample warehouse 51, and the third tray 54 moves to the exit of the sample warehouse 51 under the action of the eighth linear module 53.

[0108] Then the fifth driving member 58 opens the fifth cover 56, the hooking member 59 extends into the outlet of the sample outlet bin 51 of the ninth linear module 60 and hooks the loader a, and then hooks the loader a onto the second conveying track 52. The fifth driving member 58 closes the fifth cover 56, and the loader a is transported to the end by the second conveying track 52. The second transfer component corresponding to the sample outlet isolation conveying component transfers the loader a to the transfer box 3 for discharging.

[0109] The specific embodiments described herein are merely examples of the spirit of the present invention. Those skilled in the art may make various modifications or additions to the specific embodiments described or replace them in similar ways, but they will not deviate from the spirit of the present invention or exceed the scope defined by the appended claims.

Claims

1. A microbial intelligent incubation system, characterized in that: The invention comprises a box body (1), wherein a first vertical partition (2) is provided in the box body (1) for dividing the inner cavity of the box body (1) into an operation cavity and a culture cavity, wherein an inlet and outlet sample isolation conveying component for conveying a loader (a) between the operation cavity and the culture cavity is provided on the first vertical partition (2), wherein a heating component, a bearing component for placing the loader (a) and a first transfer component for transferring the loader (a) between the bearing component and the inlet and outlet sample isolation conveying component are provided in the culture cavity, wherein a transfer box (3) is provided in the operation cavity, wherein a second transfer component for transferring the loader (a) between the transfer box (3) and the inlet and outlet sample isolation conveying component and a detection chamber (4) are provided, wherein a detection component for detecting the growth condition of microorganisms in the loader (a) is provided in the detection chamber (4).

2. The microbial intelligent incubation system according to claim 1, characterized in that: A filter chamber (5) is provided at the top of the operation chamber, a filter (6) is provided in the filter chamber (5), an inlet of the filter (6) is communicated with the upper part of the culture chamber, an outlet of the filter (6) is communicated with the lower part of the culture chamber via a pipeline (7), and a circulating fan (8) is provided in series on the pipeline (7).

3. The microbial intelligent incubation system according to claim 2, characterized in that: A transverse partition (9) is provided at the lower part of the culture chamber, and a protective chamber (10) is provided below the transverse partition (9). The outlet of the pipeline (7) is connected to the protective chamber (10), and a plurality of flow equalization holes (11) are provided on the transverse partition (9).

4. The microbial intelligent incubation system according to claim 3, characterized in that: An air intake bin (12) is provided on the side of the protection cavity (10); a plurality of evenly distributed through holes (13) for communicating with the protection cavity (10) are provided on the side of the air intake bin (12) facing the protection cavity (10); an outlet of the pipeline (7) is communicated with the air intake bin (12); and a heating element (14) for heating is provided on the air intake bin (12).

5. The microbial intelligent incubation system according to claim 4, characterized in that: A second vertical partition (15) is provided in the box body (1), the bearing assembly and the first transfer assembly are located on one side of the second vertical partition (15), and the air intake bin (12), the pipeline (7) and the circulation fan (8) are located on the other side of the second vertical partition (15).

6. The microbial intelligent incubation system according to claim 2, characterized in that: The side of the detection chamber (4) is provided with an opening (17) connected to the culture chamber, the opening (17) is provided with a first cover plate (18) for covering the opening (17), the detection chamber (4) is provided with a first driving member (19) for opening / closing the first cover plate (18), and the detection chamber (4) is provided with a first negative pressure adsorption hole (20) connected to the inlet of the filter (6).

7. The microbial intelligent incubation system according to claim 1 or 6, characterized in that: The detection assembly comprises a first tray (22) arranged in the detection chamber (4) and driven by a first linear module (21), a cover opening module (23) and a photographing chamber (24) arranged in sequence along the movement path of the first tray (22), a camera module (25) being arranged on the top of the photographing chamber (24), and a lighting lamp (26) for illumination being arranged on the side of the photographing chamber (24).

8. The microbial intelligent incubation system according to claim 7, characterized in that: The end of the photographing chamber (24) away from the cover module (23) is slidably matched with a movable cover (27), and the left and right sides of the movable cover (27) are respectively provided with guide grooves (28). The photographing chamber (24) is provided with a guide bar (29) slidably matched with the guide groove (28), and the guide bar (29) is threadedly connected with a locking nut for pressing the movable cover (27) when the movable cover (27) is moved into place. The illuminating lamp (26) is arranged on the inner side of the movable cover (27).

9. The microbial intelligent incubation system according to claim 7, characterized in that: At least one adsorption seat (30) is provided in the detection chamber (4) and is located on the side of the cover opening module (23); a second negative pressure adsorption hole (31) is provided on the side of the adsorption seat (30) facing the cover opening module (23); a third negative pressure adsorption hole (32) is provided on the photographing chamber (24); the second negative pressure adsorption hole (31) and the third negative pressure adsorption hole (32) are respectively connected to the inlet of the filter (6).

10. The microbial intelligent incubation system according to claim 3, characterized in that: The first transport component comprises four third linear modules (33) respectively arranged at the four corners of the culture chamber, a fourth linear module (34) driven by the third linear module (33) and arranged horizontally, a fifth linear module (35) driven by the fourth linear module (34) and arranged horizontally, a rotating module (36) arranged on the fifth linear module (35), and a second clamp driven by a second electric finger arranged on the rotating module (36), wherein the fourth linear module (34) is perpendicular to the fifth linear module (35).

11. The microbial intelligent incubation system according to claim 10, characterized in that: The four third linear modules (33) are driven by the same motor, and the motor for driving the third linear modules (33) is located in the protective cavity (10).

12. The microbial intelligent incubation system according to claim 1, characterized in that: The supporting components are multiple and are evenly arranged on two opposite sides of the culture chamber along the upper and lower directions of the box body (1); the supporting components include a support plate (37), a partition frame (38) arranged on the support plate (37) and a mounting frame (39) arranged on the partition frame (38); the partition frame (38) is provided with a plurality of placement cavities compatible with the loader (a); the bottom of the placement cavity is the support plate (37); the support plate (37) is provided with a plurality of clearance openings (40) arranged in a one-to-one correspondence with the placement cavities.

13. The microbial intelligent incubation system according to claim 1, characterized in that: The sample inlet and outlet isolation and conveying components comprise a sample inlet isolation and conveying component and a sample outlet isolation and conveying component, and the sample inlet isolation and conveying component and the sample outlet isolation and conveying component correspond to different second transfer components and transfer boxes (3) respectively.

14. The microbial intelligent incubation system according to claim 13, characterized in that: The sample injection isolation and conveying assembly comprises a sample injection chamber (41) having an inlet and an outlet, a first conveying track (42) arranged outside the inlet of the sample injection chamber (41), and a second tray (44) arranged in the sample injection chamber (41) and driven by a sixth linear module (43). The inlet and outlet of the sample injection chamber (41) are arranged opposite to each other, the inlet of the sample injection chamber (41) is provided with a second cover plate (45), the outlet of the sample injection chamber (41) is provided with a third cover plate (46), a second driving member (47) for opening / closing the second cover plate (45) and a third driving member (48) for opening / closing the third cover plate (46) are arranged in the sample injection chamber (41), and a pushing member (49) for pushing a loader (a) on the first conveying track (42) into the sample injection chamber (41) is also provided on the sample injection chamber (41), and the pushing member (49) is driven by a seventh linear module (50).

15. The microbial intelligent incubation system according to claim 13, characterized in that: The sample output isolation and conveying assembly comprises a sample output bin (51) having an inlet and an outlet, a second conveying track (52) arranged outside the outlet of the sample output bin (51), and a third tray (54) arranged in the sample output bin (51) and driven by an eighth linear module (53). The inlet and outlet of the sample output bin (51) are arranged opposite to each other, the inlet of the sample output bin (51) is provided with a fourth cover plate (55), the outlet of the sample output bin (51) is provided with a fifth cover plate (56), a fourth driving member (57) for opening / closing the fourth cover plate (55) and a fifth driving member (58) for opening / closing the fifth cover plate (56) are arranged in the sample output bin (51), and a hooking member (59) for hooking a loader (a) on the third tray (54) to the second conveying track (52) is also provided on the sample output bin (51), and the hooking member (59) is driven by a ninth linear module (60).

16. The microbial intelligent incubation system according to claim 15, characterized in that: A slot (61) is provided at the end of the hook member (59), a blocking block (62) is rotatably provided in the slot (61), when the hook member (59) extends into the sample outlet chamber (51), the blocking block (62) swings toward the slot (61), a blocking surface (63) is provided in the slot (61), when the hook member (59) moves outward from the sample outlet chamber (51), the upper end of the blocking block (62) abuts against the blocking surface (63).

17. The microbial intelligent incubation system according to claim 1, characterized in that: The second transfer assembly comprises a tenth linear module (64) arranged vertically, an eleventh linear module (65) arranged on the tenth linear module (64) and driven by the tenth linear module (64), and a negative pressure suction cup (66) arranged on the eleventh linear module (65) and driven by the eleventh linear module (65), wherein the eleventh linear module (65) extends horizontally.

18. The microbial intelligent incubation system according to claim 1, characterized in that: The box body (1) is provided with a vent hole (67) for communicating with the culture chamber, and a vent valve is provided at the vent hole (67).

19. The microbial intelligent incubation system according to claim 7, characterized in that: It also includes a control system for controlling the actions of various components in the box (1); the camera module (25) is connected to the control system via a connector; the connector is used to transmit image signals captured by the camera module (25) to the control system.

20. The microbial intelligent incubation system according to claim 19, characterized in that: A temperature sensor, a humidity sensor and a gas concentration sensor are arranged in the culture chamber, and signal output ends of the temperature sensor, the humidity sensor and the gas concentration sensor are respectively connected to input ends of the control system.

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