A teaching experimental device for preparing Dendrobium officinale flavonoids dripping pills

Abstract

The present invention discloses a teaching experiment equipment for preparing Dendrobium officinale flavonoid pills, comprising: a pill forming cylinder vertically mounted on a base, wherein the pill forming cylinder contains a coolant, and a dripping hole is arranged above the pill forming cylinder; a liquid medicine cylinder mounted above the pill forming cylinder, wherein a liquid outlet is arranged below the liquid medicine cylinder, and a solenoid valve is arranged at the liquid outlet to control the liquid outlet amount; the present invention can quickly sample at different heights after adjusting the experimental parameters each time through the design of a sampling cylinder, a sampling port, a blocking block and a sampling rod, without the need for complicated operation steps. This greatly shortens the experimental cycle and improves the efficiency of the teaching experiment. The sample storage port on the sampling rod coincides with the sampling port axis, thereby ensuring the integrity of the sample during the sampling process and avoiding contamination or loss of the sample during the sampling process.

Description

Technical Field

[0001] The invention relates to teaching experimental equipment for preparing dendrobium officinale flavone dropping pills, belonging to the technical field of teaching experimental equipment. Background Art

[0002] Dendrobium candidum is an orchid herb, which is mainly distributed in Guizhou, Yunnan and Guangxi. The flavonoid extracts contained in it have obvious pharmacological effects such as anti-tumor, lowering blood pressure, lowering blood sugar, anti-oxidation, delaying aging, and enhancing immunity. The flavonoid extracts of Dendrobium candidum are generally made into pills for easy consumption. The pill machine is a kind of equipment used in the pharmaceutical industry, mainly used for the preparation of pills of medicines. The pill is a solid drug form. Its production process is to drip the liquid drug solution into the air flow or on the hot surface to form small pellets, which are then dried, cooled and other processing steps to finally obtain pills for oral administration.

[0003] Pill machines are often used to prepare pills with certain shape, hardness, disintegration requirements, and are especially suitable for drugs whose active ingredients need to be slowly released in the body (such as sustained-release preparations and controlled-release preparations). This equipment can achieve efficient production and accurately control the size and quality of pills, and is an indispensable part of the modern pharmaceutical industry.

[0004] First, the drug is dissolved in a solvent to form a drug solution or suspension of a certain concentration. The liquid drug is dripped into the air through a nozzle or accelerated by an airflow or heat source to form droplets. The droplets cool and solidify in the air / liquid, and finally form pellets. After the droplets, the particles need to be dried to remove excess solvent to ensure the stability and quality of the pills. In this process, factors such as airflow, temperature, and humidity will affect the quality of the pills.

[0005] Pill machines are often used to prepare pills with certain shape, hardness, disintegration requirements, and are especially suitable for drugs whose active ingredients need to be slowly released in the body (such as sustained-release preparations and controlled-release preparations). This equipment can achieve efficient production and accurately control the size and quality of pills, and is an indispensable part of the modern pharmaceutical industry.

[0006] However, due to its operational complexity, sensitivity to environmental conditions and high requirements for production precision, the pill machine is more used in industrial production and less suitable for teaching experiments. In particular, Dendrobium officinale flavonoids are generally sensitive to light, heat and oxygen. During the preparation of the pills, they may decompose or become inactive, resulting in different quality of the prepared pills.

[0007] In teaching experiments, the existing pill machines are mostly operated for teaching demonstrations. However, in teaching demonstrations, since the parameter demonstration adjustment scheme is fast, each adjustment scheme needs to be sampled and retained for subsequent analysis, adjustment and monitoring. The working principle of the pill machine usually involves multiple steps and precise adjustments. The setting, operation and monitoring of the equipment require a high degree of professional knowledge and experience, and students often find it difficult to master the operating procedures in a short period of time. The difficulty of sampling has increased the periodicity and tediousness of the experiment. This poses a challenge to the timeliness of teaching and the smoothness of the experimental process.

[0008] Therefore, the purpose of this study is to design a pill machine that can quickly perform high-precision sampling of pill samples adjusted with different schemes during teaching demonstration operations, while reducing the complexity of the sampling operation to meet the needs of continuous monitoring and adjustment, so that it has ideal applicability in teaching experiments. Summary of the invention

[0009] In view of the shortcomings of the prior art, the purpose of the present invention is to provide a teaching experimental equipment for preparing Dendrobium officinale flavonoids pills to solve the problems of the prior art.

[0010] In order to achieve the above object, the present invention is implemented through the following technical solutions:

[0011] A teaching experimental device for preparing Dendrobium officinale flavonoids pills, comprising: a pill forming cylinder vertically mounted on a base, wherein a coolant is contained in the pill forming cylinder, and a dripping hole is provided above the pill forming cylinder;

[0012] A medicine liquid cylinder is installed above the pill forming cylinder, a liquid outlet is provided below the medicine liquid cylinder, and a solenoid valve is arranged at the liquid outlet to control the liquid outlet amount;

[0013] A sampling assembly is arranged on the side of the drop pill forming cylinder, and the sampling assembly comprises:

[0014] A sampling cylinder is laterally inserted into the inner side of the drop pill forming cylinder, and a one-way opening channel is provided on the side of the sampling cylinder facing the outside, and a sampling port connected to the drop pill forming cylinder is provided above the channel;

[0015] A blocking block movably installed inside the channel is provided below the sampling port;

[0016] A sampling rod inserted in the channel, with a sample storage port corresponding to the sampling port being arranged above the sampling rod;

[0017] The sampling rod is inserted into the sampling cylinder transversely along the channel, and the end of the sampling rod pushes the blocking block to separate from the sampling port. The sampling port coincides with the axis of the sample storage port to receive the formed pills input from the liquid outlet through the liquid cylinder into the pill forming cylinder.

[0018] As a further improvement, the sampling tube is longitudinally movably installed inside the drop pill forming tube.

[0019] As a further improvement, a vertical through groove is provided on the side of the drop pill forming cylinder, and a group of inner grooves are provided on the side of the through groove;

[0020] The sampling assembly also includes a seal for closing the through slot;

[0021] The sampling tube is vertically mounted on the seal, and the channel passes through the seal;

[0022] The sampling rod inserted into the sampling cylinder is driven to slide in the through groove in cooperation with the sealing strip, thereby controlling the rise / fall of the sampling cylinder.

[0023] As a further improvement, the length of the seal is twice the length of the through slot.

[0024] As a further improvement, the sealing strip is a rubber strip, and a plurality of metal strips are embedded inside the rubber strip, and the sampling tube is welded to the metal strips.

[0025] As a further improvement, a group of convex strips are provided on one side of the seal strip corresponding to the position of the inner groove, and the convex strips are slidably embedded in the inner groove;

[0026] The edge of the long side of the inner groove extends inward to form a first limiting portion;

[0027] The middle part of the long side of the convex strip is recessed inward to form a second limiting portion. The first limiting portion is clamped in the second limiting portion to form a reverse force with the cooperation of the convex strip and the inner groove.

[0028] As a further improvement, a group of baffles are further arranged on the outer side of the through groove, and the baffles are embedded on the outer side of the drop pill forming cylinder, and the baffles are made of rubber material.

[0029] As a further improvement, a spring is welded on the side of the blocking block away from the sampling rod, and the other end of the spring is embedded in the end of the channel. When the spring is unfolded, the blocking block fits the sampling port.

[0030] As a further improvement, a silicone sheet is embedded on the upper surface of the blocking block.

[0031] As a further improvement, an output port is provided below the pill forming cylinder, the output port is externally connected to a discharge pipe and a first pump, a filter plate is obliquely provided at the end of the discharge pipe, a coolant reflux pipe and a second pump are provided below the filter plate, the end of the coolant reflux pipe is connected to the pill forming cylinder, the first pump is started to output the pills in the pill forming cylinder through the output port, the coolant is separated by the filter plate, and the second pump is started to input the coolant into the pill forming cylinder through the coolant reflux pipe.

[0032] Beneficial effects:

[0033] The present invention adopts the design of the sampling tube, the sampling port, the blocking block and the sampling rod, so that the pills formed in the pill forming tube can be sampled after each adjustment of the experimental parameters. The sample storage port on the sampling rod coincides with the axis of the sampling port, thereby ensuring the integrity of the sample during the sampling process and avoiding contamination or loss of the sample during the sampling process.

[0034] When the variable is small and the frequency is high, the internal pellets will accumulate, so when obtaining samples, the sampling height needs to be continuously increased. To further facilitate sampling, a vertical through slot is opened on the side of the pellet forming cylinder, and a seal is added to cooperate with the sampling cylinder and the sampling rod to move up or down, so that sampling at different heights can be further realized. Since sampling is carried out quickly at different heights and no complicated operation steps are required, this greatly shortens the experimental cycle and improves the efficiency of teaching experiments.

[0035] The liquid outlet at the bottom of the medicine cylinder is controlled by a solenoid valve, so that the amount of medicine added can be precisely adjusted. Students only need to press a button to complete it, reducing the complexity and error of manual control.

[0036] The liquid supply between the flavonoid dropping pill mixing cylinder and the liquid medicine cylinder is automatically controlled by a pump, ensuring a stable supply of liquid medicine. Students can focus on adjusting and observing experimental parameters without being distracted by the management of liquid medicine.

[0037] The entire device adopts a modular design, which is easy for students to understand and operate. The functions of each component are clear and the operation process is simple, which is suitable for use in teaching experiments.

[0038] Through the rapid sampling component and automatic control module, the problem of complex operation and difficult sampling of the traditional pill machine in teaching is solved, which significantly improves the efficiency, accuracy and teaching effect of the experiment. Compared with the existing technology, this equipment is more suitable for the teaching environment and can better meet the needs of teaching experiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0040] Figure 1 The invention discloses a three-dimensional structural schematic diagram of a teaching experimental device for preparing Dendrobium officinale flavonoids dropping pills.

[0041] Figure 2 The invention is a schematic diagram of the side structure of a teaching experimental device for preparing Dendrobium officinale flavonoids dropping pills.

[0042] Figure 3 The present invention is a schematic diagram of a partially enlarged side view of the seal in a cross-sectional view of a teaching experimental device for preparing Dendrobium officinale flavonoids dropping pills.

[0043] Figure 4 It is a partially enlarged top view schematic diagram of the seal installation state in the cross-sectional view of a teaching experimental equipment for preparing Dendrobium Officinale Flavonoid Drop Pills of the present invention.

[0044] Figure 5 The present invention is a partially enlarged schematic diagram of a sampling tube in a cross-sectional view of a teaching experimental device for preparing Dendrobium officinale flavonoid dropping pills.

[0045] Figure 6 The invention discloses a schematic diagram of connecting modules of a teaching experiment device for preparing Dendrobium officinale flavonoids dropping pills.

[0046] 1. Pill forming cylinder; 11. Dropping hole; 2. Medicine liquid cylinder; 21. Liquid outlet; 22. Solenoid valve; 3. Base; 4. Sampling cylinder; 41. Channel; 42. Sampling port; 43. Blocking block; 431. Silicone sheet; 44. Spring; 5. Sampling rod; 51. Sample storage port; 12. Through groove; 13. Inner groove; 6. Seal; 61. Rubber strip; 62. Metal strip; 14. Raised strip; 15. First limiting part; 16. Second limiting part; 17. Baffle; 71. Discharge pipe; 72. First pump; 73. Filter plate; 74. Coolant reflux pipe; 75. Second pump; 76. Flavonoid pill mixing cylinder; 77. Third pump; 78. Feed pipe; 7. Control module. DETAILED DESCRIPTION

[0047] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the invention claimed for protection, but merely represents the selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0048] In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0049] Reference Figure 1-6 As shown, a teaching experimental device for preparing Dendrobium officinale flavonoids dripping pills comprises:

[0050] A pill forming cylinder 1 is vertically mounted on a base 3, wherein a coolant is contained in the pill forming cylinder 1, and a dripping hole 11 is provided above the pill forming cylinder 1;

[0051] A medicine liquid cylinder 2 is installed above the pill forming cylinder 1, a liquid outlet 21 is provided below the medicine liquid cylinder 2, and a solenoid valve 22 is arranged at the liquid outlet 21 to control the liquid outlet amount of the liquid outlet 21;

[0052] The sampling assembly is arranged on the side of the drop pill forming cylinder 1, and the sampling assembly comprises:

[0053] A sampling cylinder 4 is laterally inserted into the inner side of the drop pill forming cylinder 1, and a one-way opening channel 41 is provided on the side of the sampling cylinder 4 facing the outside, and a sampling port 42 connected to the drop pill forming cylinder 1 is provided above the channel 41;

[0054] A blocking block 43 movably installed inside the channel 41 is provided below the sampling port 42;

[0055] A sampling rod 5 is inserted into the channel 41, and a sample storage port 51 corresponding to the sampling port 42 is arranged above the sampling rod 5;

[0056] The sampling rod 5 is inserted into the sampling tube 4 transversely along the channel 41, and the end of the sampling rod 5 pushes the blocking block 43 to separate from the sampling port 42. The sampling port 42 coincides with the axis of the sample storage port 51, and receives the formed pills input from the liquid outlet 21 through the medicine liquid cylinder 2 into the pill forming tube 1.

[0057] It also includes a flavonoid pill liquid mixing cylinder 76 and a third pump 77 installed on the base 3. The flavonoid pill liquid mixing cylinder 76 is connected to the medicine liquid cylinder 2 through a feeding pipe 78. The third pump 77 is started to input the flavonoid pill liquid in the flavonoid pill liquid mixing cylinder 76 into the medicine liquid cylinder 2 through the feeding pipe 78.

[0058] The system further includes a control module 7 , which is electrically connected to the first pump 72 , the second pump 75 , the third pump 77 , and the solenoid valve 22 .

[0059] Since Dendrobium candidum mainly contains polysaccharides, alkaloids, flavonoids and other ingredients. Flavonoid extracts mainly contain apigenin, rutin, quercetin, naringenin and other ingredients, which have obvious pharmacological effects such as anti-tumor, lowering blood pressure, lowering blood sugar, anti-oxidation, delaying aging, and enhancing immunity. Previous studies have shown that the extraction and separation of flavonoid components in Dendrobium candidum are relatively difficult, and its water solubility is poor, which is not conducive to human absorption. Therefore, a column 8 is provided for separating the flavonoid components of Dendrobium officinale, specifically, a column 8 is provided above the base 3, the column 8 contains the reaction solution containing Dendrobium officinale, the column 8 is fixed by a bracket 9 fixed on the side of the flavonoid pill liquid mixing cylinder 76, the extract obtained by extracting the dry powder of the original medicinal material of Dendrobium officinale with ethanol is dried under reduced pressure to obtain a powder added to the column 8, and the Dendrobium officinale flavonoid liquid is obtained by separation by the chromatography column, the flavonoid liquid is dried into powder, and then placed in the flavonoid pill liquid mixing cylinder 76 for mixing to form a flavonoid pill liquid, which is transported and supplemented to the liquid medicine cylinder 2 for pill operation. Compared with the existing equipment, the separation of flavonoid components can be achieved.

[0060] The cooling liquid is a drop pill, which refers to a preparation made by heating, melting and mixing solid or liquid drugs with a matrix, dropping them into an immiscible condensate, and condensing and shrinking them. In fact, it is a solid dispersion made into a drop pill, which is a better way to improve the oral bioavailability of poorly soluble drugs; it also has the advantages of simple production equipment, easy operation, small weight difference, low production cost, no dust, and is conducive to labor protection; choosing different matrices can adjust the release rate or dissolution time of the active ingredient; it can increase the stability of the drug, etc.

[0061] The pellet forming cylinder 1 is filled with cooling liquid to ensure that the pellets solidify quickly during the cooling process to form stable pellet particles. A dripping hole 11 is provided above the pellet forming cylinder 1 to drip the liquid medicine into the cooling liquid.

[0062] A liquid outlet 21 is provided at the bottom of the liquid medicine cylinder 2, and the liquid outlet amount of the liquid medicine is controlled by an electromagnetic valve 22 to ensure that the amount of liquid medicine dripped in each time is consistent, thereby improving the repeatability of the experiment.

[0063] It is laterally inserted on the inner side of the pill forming cylinder 1 and is provided with a one-way opening channel 41 , and a sampling port 42 is provided above the channel 41 .

[0064] A blocking block 43 movably installed inside the channel 41 is provided below the sampling port 42 , and the blocking block 43 keeps the sampling port 42 closed in a non-sampling state.

[0065] Inserted inside the channel 41, a sample storage port 51 is provided above the sampling rod 5. By pushing the sampling rod 5, the blocking block 43 is pushed away from the sampling port 42, so that the sampling port 42 and the sample storage port 51 coincide with each other, thereby quickly sampling.

[0066] Through the design of the sampling tube 4, the sampling port 42, the blocking block 43 and the sampling rod 5, sampling can be performed quickly after adjusting the experimental parameters each time without complicated operation steps, which greatly shortens the experimental cycle and improves the efficiency of the teaching experiment.

[0067] The sample storage port 51 on the sampling rod 5 coincides with the axis of the sampling port 42 , thereby ensuring the integrity of the sample during the sampling process and preventing the sample from being contaminated or lost during the sampling process.

[0068] The liquid outlet 21 below the medicine liquid cylinder 2 is controlled by a solenoid valve 22, so that the amount of liquid medicine added can be precisely adjusted. Students only need to operate a simple button to complete it, reducing the complexity and error of manual control.

[0069] The liquid supply between the flavonoid pill mixing cylinder 76 and the liquid medicine cylinder 2 is automatically controlled by a pump, which ensures a stable supply of liquid medicine. Students can focus on adjusting and observing experimental parameters without being distracted by the management of liquid medicine.

[0070] The entire device adopts a modular design, which is easy for students to understand and operate. The functions of each component are clear and the operation process is simple, which is suitable for use in teaching experiments.

[0071] The rapid sampling component and the automatic control module 7 solve the problems of complicated operation and difficult sampling of the traditional pill machine in teaching, and significantly improve the efficiency, accuracy and teaching effect of the experiment. Compared with the existing technology, the device is more suitable for the teaching environment and can better meet the needs of teaching experiments.

[0072] When the variable is small and the frequency is high, the internal pills will accumulate, so when obtaining samples, the sampling height needs to be continuously increased. To further facilitate sampling, the sampling cylinder 4 is longitudinally movably installed inside the pill forming cylinder 1. A vertical through groove 12 is provided on the side of the pill forming cylinder 1, and a group of inner grooves 13 are provided on the side of the through groove 12;

[0073] The sampling assembly further comprises a seal 6 for closing the through slot 12;

[0074] The sampling tube 4 is vertically mounted on the seal 6, and the channel 41 passes through the seal 6;

[0075] The sampling rod 5 inserted into the sampling tube 4 is driven to slide in the through groove 12 in cooperation with the sealing strip 6 to control the rise / fall of the sampling tube 4 .

[0076] The length of the sealing strip 6 is twice the length of the through slot 12 .

[0077] The sealing strip 6 is a rubber strip 61 , and a plurality of metal strips 62 are embedded inside the rubber strip 61 . The sampling tube 4 is welded to the metal strips 62 .

[0078] The sampling tube 4 is longitudinally movably mounted inside the pill forming tube 1, and the design of the through slot 12 and the seal 6 allows the sampling tube 4 to move up and down in the vertical direction. This allows for better control of the sampling position, ensuring that each sampling can be performed from a specific height of the pill forming tube 1.

[0079] By controlling the up and down movement of the sampling tube 4, samples can be accurately taken from the coolant at different heights to ensure the representativeness and accuracy of the samples.

[0080] The sampling tube 4 can avoid interference with the cooling liquid and the pellet forming process during movement, and maintain the stability of the experimental environment. The pellets at different heights can be sampled at different time points to observe the changes in the cooling process, thereby enhancing the scientificity and operability of the experiment.

[0081] In addition, a vertical through groove 12 is provided on the side of the pellet forming tube 1, and a group of inner grooves 13 are provided on the side of the through groove 12 for accommodating the seal 6 and the metal strip 62. Such a design ensures the stability and sealing of the seal 6 and the sampling tube 4 when moving.

[0082] The design of the inner groove 13 can effectively seal the through groove 12 to prevent leakage of the coolant, while maintaining the sealing of the sampling tube 4.

[0083] The cooperation between the inner groove 13 and the metal strip 62 allows the seal 6 to maintain a straight line during the sliding process, reducing shaking and deviation, and improving sampling accuracy. The design of the through groove 12 makes the operation of the sampling tube 4 more intuitive and convenient, and students can easily adjust it.

[0084] The seal 6 is used to seal the through slot 12 to prevent the coolant from leaking. The seal 6 is twice as long as the through slot 12, and a metal strip 62 is embedded in the rubber material and the sampling tube 4 is welded.

[0085] The seal 6 made of rubber material has good sealing performance and can effectively prevent the coolant from leaking from the through groove 12, ensuring the safety and stability of the experiment. The length of the seal 6 is twice the length of the through groove 12, ensuring that the seal 6 can always close the through groove 12 when the sampling tube 4 moves up and down, preventing the coolant from leaking during the sampling process. The embedded metal strip 62 enhances the rigidity of the seal 6, ensuring that the seal 6 will not deform during the sliding process, maintaining the vertical position of the sampling tube 4, and improving the sampling accuracy.

[0086] When in use, the pill forming cylinder 1 is fixed on the base 3, and a proper amount of coolant is injected into the cylinder. The liquid medicine cylinder 2 is installed above the pill forming cylinder 1, and it is ensured that the liquid outlet 21 is aligned with the dripping hole 11.

[0087] The flavonoid pill liquid mixing cylinder 76 is connected to the third pump 77 to ensure the normal operation of the liquid medicine supply system.

[0088] According to the experimental requirements, the seal 6 and the sampling tube 4 are slid to the required sampling height along the through groove 12 by a manual driving device. For example, if it is necessary to sample the coolant from different heights, the sampling tube 4 can be slid to these height positions respectively.

[0089] The third pump 77 is started to input the flavonoid pill liquid into the medicine liquid cylinder 2 through the feeding pipe 78 to form a medicine liquid with a certain concentration.

[0090] The electromagnetic valve 22 is activated by the control module 7, and the liquid medicine drips from the liquid outlet 21 of the liquid medicine cylinder 2 into the coolant in the pill forming cylinder 1 to form pill-shaped particles.

[0091] When sampling is required, the sampling rod 5 is inserted into the sampling tube 4 , and the end of the sampling rod 5 pushes the blocking block 43 to separate it from the sampling port 42 .

[0092] After the blocking block 43 is separated from the sampling port 42 , the axes of the sampling port 42 and the sample storage port 51 coincide with each other, and the pellet-shaped particles enter the sample storage port 51 through the sampling port 42 , thereby completing the sampling.

[0093] After the sampling is completed, the sampling rod 5 is withdrawn, and the blocking block 43 is automatically reset to close the sampling port 42 .

[0094] The sampling rod 5 is taken out, and the sample in the sample storage port 51 is transferred to the sample collection container. The sample is dried, cooled, and subjected to subsequent treatments for further analysis and detection.

[0095] As a further improvement, a group of convex strips 14 are provided on one side of the seal strip 6 corresponding to the position of the inner groove 13, and the convex strips 14 are slidably embedded in the inner groove 13;

[0096] The edge of the long side of the inner groove 13 extends inward to form a first limiting portion 15;

[0097] The middle part of the long side of the convex strip 14 is recessed inward to form a second limiting portion 16 . The first limiting portion 15 is clamped in the second limiting portion 16 to form a reverse force with the cooperation of the convex strip 14 and the inner groove 13 .

[0098] A set of convex strips 14 are arranged on one side of the seal 6 at the position corresponding to the inner groove 13, and the convex strips 14 are slidably embedded in the inner groove 13 to ensure the stability and sealing of the seal 6 and the sampling tube 4 during the sliding process. The cooperation between the convex strips 14 and the inner groove 13 enables the seal 6 to maintain a straight line when sliding, reduces shaking and deviation, ensures that the vertical position of the sampling tube 4 is not affected, and improves the sampling accuracy. The close cooperation between the inner groove 13 and the convex strips 14 can effectively prevent the coolant from leaking from the through groove 12, and ensure the stability and safety of the experimental environment.

[0099] The first limiting portion 15 and the second limiting portion 16 are arranged such that the first limiting portion 15 is extended inwardly along the long side edge of the inner groove 13, and the second limiting portion 16 is formed by recessing inwardly in the middle of the long side of the convex strip 14. The first limiting portion 15 is clamped in the second limiting portion 16, and forms a reverse force with the convex strip 14 and the inner groove 13.

[0100] The first stopper 15 is clamped in the second stopper 16 to form a reverse force, which can effectively prevent the seal 6 from sliding and falling off during the sliding process. Even during vibration or operation, the seal 6 can remain stable. The cooperation between the first stopper 15 and the second stopper 16 can further enhance the sealing effect, so that the coolant does not leak when the seal 6 slides.

[0101] In order to improve the appearance of the outer surface, a group of baffles 17 are further provided on the outer side of the through groove 12. The baffles 17 are embedded on the outer side of the pill forming cylinder 1 and are made of rubber material.

[0102] To achieve automatic resetting of the blocking block 43 , a spring 44 is welded to the side of the blocking block 43 away from the sampling rod 5 , and the other end of the spring 44 is embedded in the end of the channel 41 . When the spring 44 is unfolded, the blocking block 43 fits against the sampling port 42 .

[0103] In order to further enhance the sealing effect of the blocking block 43, a silicone sheet 431 is embedded on the upper surface of the blocking block 43. The silicone sheet 431 is embedded on the upper surface of the blocking block 43. The silicone sheet 431 has good flexibility and sealing properties, and can further enhance the sealing effect between the blocking block 43 and the sampling port 42.

[0104] A spring 44 is welded on the side of the blocking block 43 away from the sampling rod 5, and the other end of the spring 44 is embedded in the end of the channel 41. When the sampling rod 5 is inserted, the spring 44 is compressed, and the blocking block 43 is separated from the sampling port 42; when the sampling rod 5 is withdrawn, the spring 44 is expanded, and the blocking block 43 is reattached to the sampling port 42.

[0105] The design of the spring 44 enables the blocking block 43 to automatically reset after the sampling rod 5 is withdrawn, thereby closing the sampling port 42 without manual intervention, thereby improving the simplicity and efficiency of operation.

[0106] When the spring 44 is unfolded, the blocking block 43 can fit tightly against the sampling port 42 to form a better sealing effect, thereby preventing the coolant from leaking and external pollution from entering.

[0107] The elasticity of the spring 44 can reduce the jamming phenomenon of the blocking block 43 during the sliding process, ensure that the blocking block 43 is smoothly disengaged and reset, and improve the reliability and accuracy of sampling.

[0108] An output port is provided below the pill forming cylinder 1, and the output port is externally connected to a discharge pipe 71 and a first pump 72. A filter plate 73 is obliquely provided at the end of the discharge pipe 71, and a coolant reflux pipe 74 and a second pump 75 are provided below the filter plate 73. The end of the coolant reflux pipe 74 is connected to the pill forming cylinder 1. By starting the first pump 72, the pills in the pill forming cylinder 1 are output through the output port, and the coolant is separated by the filter plate 73. The second pump 75 is started to input the coolant into the pill forming cylinder 1 through the coolant reflux pipe 74.

[0109] An outlet is provided below the drop pill forming cylinder 1 and is connected to the first pump 72 via a discharge pipe 71. In this way, the formed drop pills can be discharged from the drop pill forming cylinder 1.

[0110] By starting the first pump 72, the pills can be automatically discharged from the pill forming cylinder 1, reducing the complexity and labor intensity of manual operation.

[0111] The pump can discharge the pellets quickly and stably, improving the efficiency and continuity of the experiment.

[0112] A filter plate 73 is tilted at the end of the discharge pipe 71 to separate the coolant and the pellets. The tilted filter plate 73 can use gravity to quickly separate the coolant and the pellets, simplifying the separation steps. The tilted design makes it easier for the coolant to pass through the filter plate 73, reducing the coolant residue on the surface of the pellets and improving the drying speed and quality of the pellets.

[0113] A coolant reflux pipe 74 is provided below the filter plate 73, and the separated coolant is re-injected into the pellet forming cylinder 1 through the second pump 75. The design of the coolant reflux pipe 74 and the second pump 75 realizes the recycling of the coolant, saving resources and costs.

[0114] The circulating coolant can keep the temperature and concentration of the coolant stable, ensure the consistency of each experimental condition, and improve the repeatability of the experiment. The recycling of coolant reduces the waste after each experiment, which is more environmentally friendly and economical. The automatic coolant return reduces the steps of manual coolant replenishment, making the experimental operation easier and more efficient.

[0115] By arranging the output port, the discharge pipe 71, the inclined filter plate 73, the coolant reflux pipe 74 and the second pump 75 below the drop pill forming cylinder 1, the present solution significantly improves the automation degree, discharge efficiency, coolant separation effect and resource utilization of the drop pill machine. These improvements not only simplify the operation steps and reduce manual intervention, but also ensure the stability and repeatability of the experiment, and enhance the practicality and scientificity of the teaching experiment.

[0116] In the design of the pill machine, the pump is a mechanical device used to transport liquid or gas.

[0117] The first pump 72, the second pump 75 and the third pump 77 can be mechanical devices for conveying liquid or gas, such as peristaltic pumps or centrifugal pumps.

[0118] Peristaltic pumps deliver liquids by squeezing hoses, and are suitable for small flow, high-precision delivery tasks. The advantage of peristaltic pumps is that they do not contaminate the liquid because the liquid only contacts the hose and does not directly contact other parts of the pump.

[0119] Centrifugal pumps generate centrifugal force through the rotation of the impeller to transport liquid from the inlet to the outlet. Centrifugal pumps are suitable for larger flow conveying tasks and are simple to operate and maintain.

[0120] In this embodiment, the first pump 72 and the second pump 75 are centrifugal pumps, and the third pump 77 is a peristaltic pump.

[0121] It should be noted that the device structure and the drawings of the present invention mainly describe the principle of the present invention. In terms of the technology of the design principle, the settings of the power mechanism, power supply system and control system of the device are not fully described. On the premise that the technical personnel in this field understand the principle of the above invention, the details of the power mechanism, power supply system and control system can be clearly known. The control method of the application document is automatic control through a controller, and the control circuit of the controller can be realized by simple programming by the technical personnel in this field.

[0122] The standard parts used therein can all be purchased from the market and can be customized according to the instructions and drawings. The specific connection methods of each part adopt conventional means such as mature bolts, rivets, welding, etc. in the prior art. The machinery, parts and equipment all adopt conventional models in the prior art, and the structures and principles of the components known to technical personnel in this field can be known by these technical personnel through technical manuals or through conventional experimental methods.

[0123] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A teaching experimental device for preparing Dendrobium officinale flavonoids pills, characterized in that: include: A pill forming cylinder (1) vertically mounted on a base (3), wherein a cooling liquid is contained in the pill forming cylinder (1), and a dripping hole (11) is provided above the pill forming cylinder (1); A medicine liquid cylinder (2) mounted above the pill forming cylinder (1), a liquid outlet hole (21) being provided below the medicine liquid cylinder (2), and a solenoid valve (22) being arranged at the liquid outlet hole (21) to control the amount of liquid discharged from the liquid outlet hole (21); A sampling assembly is arranged on the side of the drop pill forming cylinder (1), and the sampling assembly comprises: A sampling cylinder (4) is laterally inserted into the inner side of the drop pill forming cylinder (1), the sampling cylinder (4) is provided with a one-way opening channel (41) on the side facing the outside, and a sampling port (42) is provided above the channel (41) and is connected to the drop pill forming cylinder (1); A blocking block (43) movably mounted inside the channel (41) is provided below the sampling port (42); A sampling rod (5) inserted into the channel (41), wherein a sample storage port (51) corresponding to the sampling port (42) is provided above the sampling rod (5); The sampling rod (5) is inserted into the sampling tube (4) transversely along the passage (41), the end of the sampling rod (5) pushes the blocking block (43) away from the sampling port (42), the sampling port (42) and the sample storage port (51) are axially aligned, and the formed droplets are received by the droplet forming tube (1) from the liquid outlet (21) through the liquid medicine cylinder (2); The sampling cylinder (4) is longitudinally movably mounted inside the pill forming cylinder (1); The pill forming cylinder (1) has a vertical through groove (12) formed on its side, and a group of inner grooves (13) are provided on the side of the through groove (12); The sampling assembly further comprises a seal (6) for sealing the through slot (12); The sampling tube (4) is vertically mounted on the seal (6), and the channel (41) passes through the seal (6); driving a sampling rod (5) inserted into the sampling tube (4) to slide in the through groove (12) in cooperation with the sealing strip (6) to control the rise / fall of the sampling tube (4); A group of convex strips (14) are provided on one side of the seal strip (6) at a position corresponding to the inner groove (13), and the convex strips (14) are slidably embedded in the inner groove (13); The edge of the long side of the inner groove (13) extends inwards to form a first limiting portion (15); The middle part of the long side of the convex strip (14) is recessed inwards to form a second limiting portion (16), and the first limiting portion (15) is clamped in the second limiting portion (16) to form a reverse force in cooperation with the convex strip (14) and the inner groove (13); A spring (44) is welded to the side of the blocking block (43) away from the sampling rod (5), and the other end of the spring (44) is embedded in the end of the channel (41). When the spring (44) is unfolded, the blocking block (43) fits into the sampling port (42).

2. A teaching experimental device for preparing Dendrobium officinale flavonoids pills according to claim 1, characterized in that: The length of the sealing strip (6) is twice the length of the through slot (12).

3. A teaching experimental device for preparing Dendrobium officinale flavonoids pills according to claim 2, characterized in that: The sealing strip (6) is a rubber strip (61), and a plurality of metal strips (62) are embedded inside the rubber strip (61), and the sampling tube (4) is welded to the metal strip (62).

4. The teaching experimental equipment for preparing Dendrobium officinale flavonoids pills according to claim 1, characterized in that: A group of baffles (17) are also provided on the outer side surface of the through groove (12), and the baffles (17) are embedded on the outer side surface of the drop pill forming cylinder (1), and the baffles (17) are made of rubber material.

5. The teaching experimental equipment for preparing Dendrobium officinale flavonoids dropping pills according to claim 1, characterized in that: A silicone sheet (431) is embedded on the upper surface of the blocking block (43).

6. The teaching experimental equipment for preparing Dendrobium officinale flavonoids dropping pills according to claim 1, characterized in that: An output port is provided below the drop pill forming cylinder (1), the output port is externally connected to a discharge pipe (71) and a first pump (72), a filter plate (73) is obliquely provided at the end of the discharge pipe (71), a coolant return pipe (74) and a second pump (75) are provided below the filter plate (73), the end of the coolant return pipe (74) is connected to the drop pill forming cylinder (1), the first pump (72) is started, the drop pills in the drop pill forming cylinder (1) are discharged through the output port, the coolant is separated by the filter plate (73), and the second pump (75) is started to input the coolant into the drop pill forming cylinder (1) through the coolant return pipe (74).

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