In-vitro diagnostic kit

Abstract

The invention is applicable to the technical field of medical supplies, and provides an in-vitro diagnostic kit which comprises a kit body, an inner cavity of the kit body is an elution treatment cavity, a containing groove is formed in the side edge of the kit body, a diagnostic kit body for diagnosis is contained in the containing groove, an elution treatment mechanism is arranged in the elution treatment cavity, and the elution treatment mechanism is arranged in the elution treatment cavity. The elution treatment mechanism is used for fully mixing body fluid adhered to a swab and an eluent in the elution pipe, and comprises a U-shaped bracket fixedly mounted on the inner wall of the bottom of the elution treatment cavity; the U-shaped support is arranged on the base, the pipe placing barrel is rotatably arranged on the top of the U-shaped support, the pipe placing barrel can ascend and descend on the U-shaped support, eluent is filled in the pipe placing barrel, and a plurality of metal elastic pieces are fixedly arranged in the pipe placing barrel. According to the in-vitro diagnostic kit provided by the scheme, through the combination of the elution treatment mechanism and the springback type swinging mechanism, the full mixing of the body fluid on the swab and the eluent is realized, the manual operation is not needed, and the mixing efficiency and accuracy are improved.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical supplies, and in particular relates to an in vitro diagnostic kit. Background Art

[0002] In vitro diagnostic kits are medical device products used to detect and analyze specific biomarkers in human samples and are widely used in medical diagnosis and health management.

[0003] After searching, the patent document with the authorization announcement number CN110312467B discloses a diagnostic kit, which can accurately detect diseases. However, in diagnostic testing, for example, after using a swab to dip the nasal cavity, it needs to be placed in an elution tube for elution. The elution operation requires lifting and rotating. The reason is to make the body fluid and the elution liquid mix better. However, the above-mentioned diagnostic kit and the prior art cannot complete this step more efficiently, resulting in low diagnostic efficiency. Summary of the invention

[0004] The present invention provides an in vitro diagnostic kit, aiming to solve the problem of low efficiency of the current elution process relying on manual operation raised in the above background technology.

[0005] To solve the above problems, the present invention is implemented as follows: an in vitro diagnostic kit comprises: a box body, the inner cavity of the box body is an elution processing chamber, a storage groove is opened on the side, the diagnostic kit body for diagnosis is stored in the storage groove, the elution processing chamber is provided with an elution processing mechanism, which is used to fully mix the body fluid adhered to the swab cotton swab with the eluent in the elution tube, and the elution processing mechanism comprises: a U-shaped bracket fixedly mounted on the inner wall of the bottom of the elution processing chamber; a tube-releasing tube rotatably mounted on the top of the U-shaped bracket, and the tube-releasing tube is rotated on the top of the U-shaped bracket. The swab is placed in the elution tube and immersed in the eluent; a rebound swing mechanism is arranged in the elution treatment chamber, and the rebound swing mechanism is used to drive the tube-releasing tube to swing back and forth so that the body fluid adhered to the swab is fully mixed with the eluent in the elution tube; and a test tube taking and placing lifting mechanism is arranged in the elution treatment chamber, and the test tube taking and placing lifting mechanism is used to lift the tube-releasing tube, and is used to take and place the elution tube and the swab.

[0006] Preferably, a take-in and put-out port communicating with the elution processing chamber is provided on the top of the box body for taking out and putting the elution tube and the swab, and the take-in and put-out port is located directly above the tube placing cylinder.

[0007] Preferably, the rebound type swing mechanism comprises a limit rotating cylinder, a spline cylinder, a skirt ring, a spline shaft, a torsion spring, a driven cam, a motor 1 and an active cam, the limit rotating cylinder is fixedly mounted on the bottom of the tube releasing cylinder, the bottom of the limit rotating cylinder is in contact with or separated from the top of the U-shaped bracket, the spline cylinder is rotatably mounted on the top of the U-shaped bracket, the skirt ring is fixedly mounted on the bottom end of the spline cylinder, the spline shaft is slidably penetrated and installed in the spline cylinder and the skirt ring, the top of the spline shaft is fixedly connected to the bottom of the tube releasing cylinder, the torsion spring is sleeved outside the spline cylinder, the two ends of the torsion spring are respectively inserted into the top and the skirt ring of the U-shaped bracket, the driven cam is fixedly sleeved on the tube releasing cylinder, the motor 1 is arranged on one side of the U-shaped bracket and fixedly connected to the inner wall of the elution processing chamber, the active cam is fixedly mounted on the output shaft of the motor 1, the active cam is located on one side of the driven cam, and the active cam and the driven cam have an intersection so that the driven cam is driven to rotate when the active cam rotates.

[0008] Preferably, a plurality of rolling balls are inlaid at the bottom of the position-limiting rotating cylinder, and the plurality of rolling balls can roll along the top of the U-shaped bracket, and the plurality of rolling balls follow the lifting and lowering of the tube-releasing cylinder and the position-limiting rotating cylinder to contact or separate from the top of the U-shaped bracket.

[0009] Preferably, a stabilizing shaft seat is rotatably provided on the output shaft of the motor 1, and the stabilizing shaft seat is fixedly connected to the inner wall of the elution processing chamber.

[0010] Preferably, the test tube placing and lifting mechanism includes a lifting ring, two winding shafts, and two lifting ropes. The lifting ring is rotatably mounted on the tube placing tube, and the two winding shafts are rotatably installed in parallel in the elution processing chamber. The two winding shafts rotate synchronously, and both of the two winding shafts are located above the lifting ring. The two lifting ropes are respectively wound around the two winding shafts, and the bottom ends of the two lifting ropes are fixedly connected to the top of the lifting ring.

[0011] Preferably, the test tube placing and lifting mechanism also includes a rectangular lifting guide groove, a rectangular guide bar, two synchronous wheels one, a synchronous belt one, a motor two, two synchronous wheels two and a synchronous belt two. The rectangular lifting guide groove is opened on the inner walls on both sides corresponding to the elution processing chamber, the rectangular guide bar is slidably installed in the rectangular lifting guide groove, the rectangular guide bar is fixedly connected to the lifting ring, the two synchronous wheels one are respectively fixedly mounted on the two winding shafts, the synchronous belt is set on the two synchronous wheels one, the motor two is fixedly installed in the elution processing chamber, the two synchronous wheels two are respectively fixedly mounted on the output shaft of the motor two and any one of the winding shafts, and the synchronous belt two is set on the two synchronous wheels two.

[0012] Preferably, a controller is provided on one side of the box body, and the controller is connected to both the motor 1 and the motor 2.

[0013] Preferably, both ends of the two winding shafts extend outside the box body, the distance between the top of the elution tube and the top of the box body is smaller than the lifting height of the tube release tube, and the spacing of the rectangular guide bar sliding and lifting along the rectangular lifting guide groove is adapted to the lifting height of the tube release tube.

[0014] Preferably, a limit screw is installed through the storage groove, the limit screw presses the diagnostic kit body, both ends of the limit screw extend out of the box body and are threadedly installed with locking nuts, and a handle is fixedly installed on the top of the box body.

[0015] Compared with the related art, the in vitro diagnostic kit provided by the present invention has the following beneficial effects:

[0016] Compared with the prior art, the in vitro diagnostic kit provided by the present invention realizes sufficient mixing of body fluid on the swab and the eluent through the combination of the elution processing mechanism and the rebound swing mechanism, without the need for manual operation, thereby improving the mixing efficiency and accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the main stereoscopic structure of an in vitro diagnostic kit provided by the present invention;

[0018] Figure 2 It is a rear view stereoscopic structural schematic diagram of an in vitro diagnostic kit provided by the present invention;

[0019] Figure 3 It is a schematic diagram of the main cross-sectional structure of an in vitro diagnostic kit provided by the present invention;

[0020] Figure 4 for Figure 3 An enlarged schematic diagram of the structure of part A shown in FIG.

[0021] Figure 5 for Figure 3 An enlarged schematic diagram of the structure of part B shown in FIG.

[0022] Figure 6 for Figure 5 An enlarged schematic diagram of the structure of part C shown in FIG.

[0023] Figure 7 for Figure 3 An enlarged structural diagram of part D shown in FIG.

[0024] Figure 8 It is a schematic diagram of the main three-dimensional structure of the elution processing mechanism and the test tube taking and placing lifting mechanism in the present invention;

[0025] Fig. 9 It is a bottom-up stereoscopic structural schematic diagram of the elution processing mechanism and the test tube taking and placing lifting mechanism in the present invention;

[0026] Fig.10 It is a schematic diagram of the main three-dimensional structure of the sealing stabilization mechanism in the present invention;

[0027] Fig.11 It is a bottom-up three-dimensional structural schematic diagram of the sealing stabilization mechanism in the present invention;

[0028] Fig.12 It is a schematic diagram of the three-dimensional structure of the side sealing mechanism in the present invention.

[0029] Figure numerals: 1, box body; 2, elution processing chamber; 3, storage slot; 4, diagnostic kit body; 5, U-shaped bracket; 6, tube release tube; 7, elution tube; 8, metal shrapnel; 9, access port; 10, swab cotton swab; 11, limited rotation cylinder; 12, spline cylinder; 13, skirt ring; 14, spline shaft; 15, torsion spring; 16, driven cam; 17, motor one; 18, active cam; 19, stable shaft seat; 20, lifting ring; 21, winding shaft; 22, lifting rope; 23, rectangular lifting guide groove; 24, rectangular guide strip; 25, synchronous wheel one; 26, synchronous belt one; 27, motor two; 28, synchronous wheel two; 29, synchronous belt two; 30, controller; 31, Limit screw; 32. Locking nut; 33. Handle; 34. Closing plate; 35. Lifting screw; 36. Assembly shaft seat; 37. Connecting shaft; 38. Assembly support arm; 39. Synchronous shaft; 40. Bevel gear; 41. Synchronous wheel three; 42. Synchronous belt three; 43. Assembly side plate; 44. Sealing tooth plate; 45. Sliding stabilizing strip; 46. Arc-shaped limit clamping plate; 47. Gear shaft; 48. Driving gear; 49. Power reversing shaft; 50. Circular gear; 51. Synchronous wheel four; 52. Synchronous belt four; 53. Tensioning roller; 54. Eluent storage box; 55. Liquid pump; 56. Lifting pipe; 57. Telescopic pipe; 58. Drain hole; 59. Filling pipe; 60. Drain pipe. DETAILED DESCRIPTION

[0030] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by technicians in the technical field of the present application; the terms used in the specification of the application herein are only for the purpose of describing specific embodiments and are not intended to limit the present application; the terms "including" and "having" in the specification and claims of the present application and the above-mentioned figure descriptions and any variations thereof are intended to cover non-exclusive inclusions. The terms "first", "second", etc. in the specification and claims of the present application or the above-mentioned figures are used to distinguish different objects, rather than to describe a specific order; the terms "inside", "outside", "left", and "right" indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, which are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.

[0031] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0032] The present invention provides an in vitro diagnostic kit. Figure 1-12 As shown, the in vitro diagnostic kit comprises: a box body 1, the inner cavity of the box body 1 is an elution processing chamber 2, and a storage groove 3 is opened on the side. The storage groove 3 stores a diagnostic kit body 4 for diagnosis, and the elution processing chamber 2 is provided with an elution processing mechanism for fully mixing the body fluid adhered to the swab 10 with the eluent in the elution tube 7. The elution processing mechanism comprises: a U-shaped bracket 5 fixedly mounted on the inner wall of the bottom of the elution processing chamber 2; a tube release tube 6 rotatably mounted on the top of the U-shaped bracket 5, and the tube release tube 6 can be raised and lowered on the U-shaped bracket 5. The release tube 6 is filled with eluent, and a plurality of metal spring pieces 8 are fixedly installed in the release tube 6 for fixing the elution tube 7 when it is placed therein. The swab cotton swab 10 is placed in the elution tube 7 and immersed in the eluent; a rebound swinging mechanism is arranged in the elution processing chamber 2, and the rebound swinging mechanism is used to drive the release tube 6 to swing back and forth so that the body fluid adhered to the swab cotton swab 10 is fully mixed with the eluent in the elution tube 7; and a test tube picking and placing lifting mechanism is arranged in the elution processing chamber 2, and the test tube picking and placing lifting mechanism is used to lift and lower the release tube 6, and is used to pick up and place the elution tube 7 and the swab cotton swab 10.

[0033] In this embodiment, when in use, the swab cotton swab 10 (with the body fluid to be tested adhered to it) is placed in the tube release tube 6 in the elution processing chamber 2. At this time, the swab cotton swab 10 is immersed in the elution liquid poured in the tube release tube 6. A plurality of metal spring pieces 8 are provided in the tube release tube 6 for fixing the elution tube 7 to ensure the stability of the elution tube 7 during the mixing process.

[0034] Afterwards, the rebound swing mechanism is activated to drive the tube release tube 6 to swing back and forth on the U-shaped bracket 5. This swinging action helps to fully mix the body fluid adhered to the swab 10 with the eluent, thereby improving the accuracy of diagnosis.

[0035] After the mixing is completed, the tube barrel 6 is raised and lowered by the test tube taking and placing lifting mechanism, so that the user can take out the mixed elution tube 7 and swab 10 for subsequent diagnostic analysis.

[0036] This solution achieves full mixing of the body fluid on the swab 10 and the elution liquid by combining the elution processing mechanism and the rebound swing mechanism, without the need for manual operation, thereby improving the mixing efficiency and accuracy.

[0037] The provision of the test tube taking and placing lifting mechanism enables the user to conveniently take and place the elution tube 7 and the swab 10, thereby simplifying the operation process and improving the convenience of use.

[0038] The eluted solution is diagnosed using the diagnostic kit body 4, which (such as the diagnostic kit described in CN110312467B) includes key components such as a diagnostic chip, a diagnostic sample movement adjustment unit, an optical information detection unit, and a controller.

[0039] After the eluent is transferred to the diagnostic reagent cartridge body 4, the diagnostic sample movement regulating unit can open / close one end of the flow channel to regulate the movement of the eluent (at this time, serving as the diagnostic sample).

[0040] The eluent moves along the flow channel, passing through the pretreatment unit (such as the area for dilution, homogenization or adding reaction reagents), the test unit (such as the area for specific reaction with a specific biomarker) and the reference unit (such as the area for providing comparison or calibration signal).

[0041] Optical information detection and analysis:

[0042] The optical information detection unit (including a light source and a sensor) performs optical detection on the biomarkers in the eluent, such as fluorescence, absorption, scattering, etc.

[0043] The controller analyzes and processes the optical information obtained by the sensor according to a preset algorithm or program to obtain a diagnosis result.

[0044] The diagnosis result can be displayed through a display unit (such as a screen, indicator light, etc.), or transmitted to an external device (such as a computer, mobile phone, etc.) through a data transmission interface (such as USB, Bluetooth, etc.) for further analysis or recording.

[0045] By transferring the eluate after elution treatment to the diagnostic kit body 4, and using the diagnostic chip, diagnostic sample movement adjustment unit, optical information detection unit and controller and other components inside it for analysis and processing, accurate detection and analysis of biomarkers can be achieved. This process not only improves the diagnostic efficiency, but also ensures the accuracy and reliability of the diagnostic results. At the same time, the design of the diagnostic kit also has high flexibility and scalability, which can adapt to different detection needs and application scenarios.

[0046] The entire diagnostic kit has a compact structure and reasonable design, which not only improves diagnostic efficiency but also reduces operational difficulty, providing a more reliable and convenient in vitro diagnostic tool for medical diagnosis.

[0047] In a further preferred embodiment of the present invention, a take-in / put-out port 9 connected to the elution processing chamber 2 is provided on the top of the box body 1 for taking out and putting the elution tube 7 and the swab 10 , and the take-in / put-out port 9 is located directly above the tube placing tube 6 .

[0048] In this embodiment, during use, the elution tube 7 and the swab 10 (which has been dipped in body fluids from the nasal cavity and other parts) can be conveniently placed in the elution processing chamber 2 through the access port 9 on the top of the box body 1, and can also be conveniently taken out.

[0049] In a further preferred embodiment of the present invention, the rebound swing mechanism includes a limit rotating cylinder 11, a spline cylinder 12, a skirt ring 13, a spline shaft 14, a torsion spring 15, a driven cam 16, a motor 17 and an active cam 18. The limit rotating cylinder 11 is fixedly installed at the bottom of the tube release cylinder 6, and the bottom of the limit rotating cylinder 11 is in contact with or separated from the top of the U-shaped bracket 5. The spline cylinder 12 is rotatably installed at the top of the U-shaped bracket 5, and the skirt ring 13 is fixedly installed at the bottom end of the spline cylinder 12. The spline shaft 14 is slidably installed in the spline cylinder 12 and the skirt ring 13. The top of 14 is fixedly connected to the bottom of the tube release tube 6, the torsion spring 15 is sleeved on the outside of the spline tube 12, and the two ends of the torsion spring 15 are respectively inserted into the top of the U-shaped bracket 5 and the skirt ring 13, the driven cam 16 is fixedly sleeved on the tube release tube 6, the motor 17 is arranged on one side of the U-shaped bracket 5 and is fixedly connected to the inner wall of the elution processing chamber 2, the active cam 18 is fixedly installed on the output shaft of the motor 17, the active cam 18 is located on one side of the driven cam 16, and the active cam 18 and the driven cam 16 have an intersection, so that when the active cam 18 rotates, the driven cam 16 is driven to rotate.

[0050] In this embodiment, the limiting rotating cylinder 11 is fixedly installed at the bottom of the tube-releasing cylinder 6 and contacts the top of the U-shaped bracket 5. The spline cylinder 12 is rotatably installed at the top of the U-shaped bracket 5, and the skirt ring 13 is fixedly installed at the bottom of the spline cylinder 12. The spline shaft 14 is slidably installed in the spline cylinder 12 and the skirt ring 13, and its top end is fixedly connected to the bottom of the tube-releasing cylinder 6, so as to realize the lifting and synchronous rotation of the tube-releasing cylinder 6 on the spline cylinder 12.

[0051] The torsion spring 15 is sleeved outside the spline cylinder 12, and its two ends are respectively inserted into the top of the U-shaped bracket 5 and the skirt ring 13 to provide a reset torque for the tube release cylinder 6. When the tube release cylinder 6 is subjected to an external force, it can rotate relative to the spline cylinder 12, and the torsion spring 15 is deformed and stores energy. When the external force disappears, the torsion spring 15 releases energy and drives the tube release cylinder 6 to reset.

[0052] The driven cam 16 is fixedly sleeved on the tube-releasing tube 6, while the motor 17 is arranged on one side of the U-shaped bracket 5 and fixedly connected to the inner wall of the elution processing chamber 2. The active cam 18 is fixedly mounted on the output shaft of the motor 17, located on one side of the driven cam 16, and has an intersection with the driven cam 16. When the motor 17 is started and drives the active cam 18 to rotate, the active cam 18 will drive the driven cam 16 to rotate, thereby driving the tube-releasing tube 6 to deflect on the spline tube 12, and compressing the torsion spring 15 at the same time. When the active cam 18 is disengaged from the driven cam 16, the torsion spring 15 is reset to realize the reciprocating swing of the tube-releasing tube 6.

[0053] In this solution, the motor 17 drives the interaction between the active cam 18 and the driven cam 16, and the torsion spring 15 is used to achieve the reciprocating swing of the tube 6. This swinging action helps to make the body fluid adhered to the swab 10 and the elution liquid mix more fully, thereby improving the elution efficiency.

[0054] In a further preferred embodiment of the present invention, a plurality of rolling balls are embedded in the bottom of the limiting rotating cylinder 11, and the plurality of balls can roll along the top of the U-shaped bracket 5, and the plurality of balls follow the lifting and lowering of the tube releasing cylinder 6 and the limiting rotating cylinder 11 to contact or separate from the top of the U-shaped bracket 5.

[0055] In this embodiment, a plurality of balls are rolled and embedded at the bottom of the limiting rotating cylinder 11. These balls can roll along the top of the U-shaped bracket 5, and as the tube placing cylinder 6 and the limiting rotating cylinder 11 are raised and lowered, they will contact or separate from the top of the U-shaped bracket 5.

[0056] When the motor 17 drives the active cam 18 to rotate, the active cam 18 moves the driven cam 16, thereby driving the tube-releasing tube 6, the position-limiting rotating tube 11 and the spline tube 12 to rotate. In this process, the ball at the bottom of the position-limiting rotating tube 11 rolls on the top of the U-shaped bracket 5, reducing the friction resistance between the position-limiting rotating tube 11 and the U-shaped bracket 5, making the lifting and rotation of the tube-releasing tube 6 smoother.

[0057] In a further preferred embodiment of the present invention, a stabilizing shaft seat 19 is rotatably provided on the output shaft of the motor 17 , and the stabilizing shaft seat 19 is fixedly connected to the inner wall of the elution processing chamber 2 .

[0058] In this embodiment, a stable shaft seat 19 is rotatably mounted on the output shaft of the motor 17, and the stable shaft seat 19 is fixedly connected to the inner wall of the elution processing chamber 2, so that when the motor 17 drives the active cam 18 to rotate, its output shaft can be more stably supported.

[0059] In a further preferred embodiment of the present invention, the test tube placing and lifting mechanism includes a lifting ring 20, two winding shafts 21, and two lifting ropes 22. The lifting ring 20 is rotatably mounted on the tube placing tube 6, and the two winding shafts 21 are rotatably installed in parallel in the elution processing chamber 2. The two winding shafts 21 rotate synchronously, and the two winding shafts 21 are both located above the lifting ring 20. The two lifting ropes 22 are respectively wound around the two winding shafts 21, and the bottom ends of the two lifting ropes 22 are fixedly connected to the top of the lifting ring 20.

[0060] In the present embodiment, the test tube placement and lifting mechanism is mainly composed of a lifting ring 20, two winding shafts 21 and two lifting ropes 22. The lifting ring 20 is rotatably sleeved on the tube release tube 6, and can keep its relative position with the tube release tube 6 unchanged as the tube release tube 6 rotates. The two winding shafts 21 are rotatably installed in the elution processing chamber 2 in parallel, and can rotate synchronously. They are all located above the lifting ring 20, and are used to wind and release the lifting ropes 22. The two lifting ropes 22 are respectively wound on the two winding shafts 21, and their bottom ends are fixedly connected to the top of the lifting ring 20.

[0061] When the elution tube 7 needs to be lifted or lowered, the lifting rope 22 can be wound or released by driving the reel 21 to rotate. Since the two reel shafts 21 rotate synchronously, the two lifting ropes 22 will be wound or released at the same speed, thereby ensuring that the hoisting ring 20 and the tube release tube 6 can be smoothly raised or lowered.

[0062] In a further preferred embodiment of the present invention, the test tube placing and lifting mechanism also includes a rectangular lifting guide groove 23, a rectangular guide bar 24, two synchronous wheels 25, a synchronous belt 26, a motor 27, two synchronous wheels 28 and a synchronous belt 29, the rectangular lifting guide groove 23 is opened on the inner walls on both sides corresponding to the elution processing chamber 2, the rectangular guide bar 24 is slidably installed in the rectangular lifting guide groove 23, the rectangular guide bar 24 is fixedly connected to the lifting ring 20, the two synchronous wheels 25 are respectively fixedly mounted on the two winding shafts 21, the synchronous belt 26 is mounted on the two synchronous wheels 25, the motor 27 is fixedly installed in the elution processing chamber 2, the two synchronous wheels 28 are respectively fixedly mounted on the output shaft of the motor 27 and any one of the winding shafts 21, and the synchronous belt 29 is mounted on the two synchronous wheels 28.

[0063] In this embodiment, rectangular lifting guide grooves 23 are provided on the inner walls on both sides corresponding to the elution treatment chamber 2 for installing and guiding the rectangular guide bar 24. The rectangular guide bar 24 is slidably installed in the rectangular lifting guide groove 23 and is fixedly connected to the lifting ring 20, so that when the lifting ring 20 is lifted or lowered, the rectangular guide bar 24 will slide in the rectangular lifting guide groove 23 to play a guiding and stabilizing role.

[0064] The two synchronous wheels 25 are respectively fixedly mounted on the two winding shafts 21, and the synchronous belt 26 is mounted on the two synchronous wheels 25 to form a closed-loop transmission system. When one of the winding shafts 21 rotates, the other winding shaft 21 is driven to rotate synchronously through the synchronous belt 26, thereby ensuring that the two lifting ropes 22 are wound or released at the same speed.

[0065] The second motor 27 is fixedly installed in the elution treatment chamber 2, and is used to drive the second synchronous wheel 28 to rotate. The two second synchronous wheels 28 are respectively fixedly sleeved on the output shaft of the second motor 27 and any one of the reel shafts 21, and the second synchronous belt 29 is sleeved on the two second synchronous wheels 28 to form a power transmission system. When the second motor 27 is started, the reel shaft 21 will be driven to rotate through the second synchronous belt 29, thereby realizing the lifting and lowering of the hoisting ring 20 and the tube release tube 6.

[0066] By adding the rectangular lifting guide groove 23 and the rectangular guide bar 24, a more stable guide and support is provided for the lifting of the hoisting ring 20, avoiding the risk of the elution tube 7 falling off or being damaged due to shaking or tilting. At the same time, the closed-loop transmission system of the synchronous wheel 1 25 and the synchronous belt 1 26 also ensures that the two lifting ropes 22 are wound or released at the same speed, further enhancing stability.

[0067] The introduction of the motor 27 makes the lifting operation of the test tube picking and placing lifting mechanism more automated and intelligent. The user only needs to control the start and stop of the motor 27 to realize the lifting operation of the hoisting ring 20 and the tube placing tube 6, which greatly improves the work efficiency and convenience.

[0068] In a further preferred embodiment of the present invention, a controller 30 is provided on one side of the box body 1 , and the controller 30 is connected to both the motor 1 17 and the motor 2 27 .

[0069] In this embodiment, the controller 30 can accurately control the parameters such as the start, stop, and speed of the motor 1 17 and the motor 2 27 through a preset program or a command input by the user. The motor 1 17 is mainly responsible for driving the rotation of the tube-releasing barrel 6, while the motor 2 27 drives the rotation of the reel 21 through the synchronous belt 29 and the synchronous wheel 28, thereby controlling the lifting and lowering of the hoisting ring 20 and the tube-releasing barrel 6.

[0070] In a further preferred embodiment of the present invention, both ends of the two winding shafts 21 extend outside the box body 1, the distance between the top of the elution tube 7 and the top of the box body 1 is smaller than the lifting height of the tube release tube 6, and the distance of the rectangular guide bar 24 sliding and lifting along the rectangular lifting guide groove 23 is adapted to the lifting height of the tube release tube 6.

[0071] In this embodiment, the distance between the top of the elution tube 7 and the top of the box body 1 is ensured to be less than the maximum lifting height of the tube placing tube 6, ensuring that the tube placing tube 6 can smoothly deliver or remove the elution tube 7 during the lifting process. In addition, the lifting distance of the rectangular guide bar 24 sliding along the rectangular lifting guide groove 23 is also accurately calculated to perfectly adapt to the lifting height of the tube placing tube 6, thereby ensuring the stability and accuracy of the tube placing tube 6 during the lifting process.

[0072] In a further preferred embodiment of the present invention, a limiting screw 31 is installed through the storage groove 3, and the limiting screw 31 presses the diagnostic kit body 4. Both ends of the limiting screw 31 extend to the outside of the box body 1 and are threadedly installed with locking nuts 32. A handle 33 is fixedly installed on the top of the box body 1.

[0073] In this embodiment, a limiting screw 31 is installed through the storage slot 3. The function of this limiting screw 31 is to press the diagnostic kit body 4 placed in the storage slot 3 to prevent it from shaking or shifting during transportation or storage. In order to ensure the stability of the limiting screw 31, both ends of the limiting screw 31 are extended to the outside of the box body 1, and a locking nut 32 is installed on the external thread. The limiting screw 31 can be removed by rotating the locking nut 32 to take out the diagnostic kit body 4.

[0074] In order to further improve the use effect of the device, in addition to the above scheme, this scheme also has the following embodiments:

[0075] In another embodiment of the present invention, a side sealing mechanism is provided on one side of the box body 1 located at the storage slot 3, and the side sealing mechanism operates synchronously with the test tube placement and lifting mechanism. The side sealing mechanism includes a sealing plate 34 slidably provided on the box body 1 at one side of the storage slot 3, for controlling the opening and closing of the storage slot 3, and the sealing plate 34 is lifted and lowered synchronously with the tube placing tube 6, and a plurality of lifting screws 35 are installed on the inner thread of the sealing plate 34, and the lifting distance driven by the plurality of lifting screws 35 is sufficient for the storage slot 3 to be fully opened, and the lowering distance is sufficient for the storage slot 3 to be fully closed, and an assembly shaft seat 36 fixedly connected to the side of the box body 1 is provided above the plurality of lifting screws 35, and the plurality of assembly shaft seats 36 A connecting shaft 37 is rotatably installed on the top, and the bottom ends of the multiple connecting shafts 37 are respectively fixedly connected to the top ends of the multiple lifting screws 35. An assembly arm 38 is fixedly installed on the top of the box body 1, and a synchronization shaft 39 is rotatably installed on the assembly arm 38. The synchronization shaft 39 rotates synchronously with the two winding shafts 21. The synchronization shaft 39 and the multiple connecting shafts 37 are fixedly sleeved with a bevel gear 40, and the bevel gears 40 on the multiple connecting shafts 37 are respectively meshed with the multiple bevel gears 40 on the synchronization shaft 39. A synchronization wheel three 41 is fixedly installed on the same end of the synchronization shaft 39 and any one of the winding shafts 21, and the two synchronization wheels three 41 are sleeved with the same synchronization belt three 42.

[0076] In this embodiment, the side sealing mechanism and the test tube placement lifting mechanism operate synchronously, ensuring the effective opening and closing of the storage slot 3 during the test tube placement process. Specifically, a sliding sealing plate 34 is provided on one side of the box body 1 located at the storage slot 3, and the sealing plate 34 is driven by a plurality of lifting screws 35. The top of the lifting screw 35 is connected to the assembly shaft seat 36 assembled on the side of the box body 1 through a connecting shaft 37, and the connecting shaft 37 and the synchronous shaft 39 are fixedly sleeved with mutually meshing bevel gears 40. The synchronous shaft 39 rotates synchronously with the two winding shafts 21 in the test tube placement lifting mechanism, and the synchronous movement of the winding shaft 21 and the synchronous shaft 39 is realized through the transmission of the synchronous wheel three 41 and the synchronous belt three 42. Therefore, when the test tube placement lifting mechanism is in operation, the side sealing mechanism will also act synchronously to ensure the smooth opening and closing of the storage slot 3 during the test tube placement process, so that the diagnostic reagent box body 4 on the side can be used after the reagent is taken out.

[0077] The synchronous operation of the side sealing mechanism and the test tube placement and lifting mechanism significantly improves the degree of automation of the entire device during the test tube placement process. The user does not need to manually operate the opening and closing of the storage slot 3, which greatly saves time and energy.

[0078] The sliding design of the closing plate 34 and the precise driving of the lifting screw 35 ensure good sealing performance of the storage slot 3 in the closed state, which can not only prevent external factors such as dust and moisture from contaminating the diagnostic kit body 4, but also ensure the safety of the test tube during storage.

[0079] In another embodiment of the present invention, a sealing stabilization mechanism is provided on the top of the box body 1 for closing the access opening 9 and fixing the swab 10, and the sealing stabilization mechanism operates synchronously with the side sealing mechanism, and the sealing stabilization mechanism includes two assembly side panels 43 fixedly mounted on the top of the box body 1, and the two assembly side panels 43 are respectively located on two opposite sides of the closed access opening 9, and two sealing tooth plates 44 are slidably mounted between the two assembly side panels 43 for closing the access opening 9, and the two sealing tooth plates 44 slide towards or away from each other, and the sliding of the two sealing tooth plates 44 is synchronized with the lifting and lowering of the closing plate 34, that is, when the closing plate 34 rises, the two sealing tooth plates 44 slide away from each other, and the storage slot 3 and the closed access opening 9 are opened synchronously, and two sliding stabilization strips 45 are fixedly mounted between the two assembly side panels 43, and the bottoms of the two sliding stabilization strips 45 are respectively in sliding contact with the tops of the two sealing tooth plates 44, so as to stabilize the sliding of the sealing tooth plates 44, and the tops of the two sealing tooth plates 44 are fixedly mounted with arc The arc-shaped limit card plate 46, the two sealing tooth plates 44 and the arc-shaped limit card plate 46 have arc-shaped grooves for buckling the swab 10 on both sides, and two gear shafts 47 are rotatably installed between the two assembly side plates 43. The two gear shafts 47 are respectively arranged corresponding to the two sealing tooth plates 44. The two gear shafts 47 are fixedly sleeved with driving gears 48. The two driving gears 48 are respectively meshed with the two sealing tooth plates 44. The two assembly side plates 43 are rotatably installed with the same power The reversing shaft 49, the power reversing shaft 49 and the adjacent gear shaft 47 are fixedly sleeved with a circular gear 50, the two circular gears 50 are meshed with each other to make the two gear shafts 47 rotate in opposite directions, the synchronous shaft 39, the power reversing shaft 49 and the other gear shaft 47 are fixedly installed with synchronous wheels 41, the three synchronous wheels 41 are sleeved with the same synchronous belt 42, and a plurality of tensioning rollers 53 are rotatably installed on the two assembly side plates 43, and the plurality of tensioning rollers 53 are in contact with the synchronous belt 42.

[0080] In this embodiment, the sealing stabilization mechanism is intended to close the access port 9 and fix the swab 10, while maintaining synchronous operation with the side sealing mechanism. The sealing stabilization mechanism is composed of two assembly side plates 43, two sealing tooth plates 44, two sliding stabilization strips 45, two arc-shaped limit clamps 46, two gear shafts 47 and driving gears 48 thereon, a power reversing shaft 49 and a circular gear 50 thereon, a synchronous wheel 4 51 and a synchronous belt 4 52, and a plurality of tensioning rollers 53. The two assembly side plates 43 are fixedly mounted on the top of the box body 1, located on the opposite sides of the closed access port 9, and the sealing tooth plates 44 slide between the assembly side plates 43 to close the access port 9. The sliding stabilization strip 45 ensures that the sealing tooth plates 44 slide stably, and the arc-shaped limit clamps 46 cooperate with the sealing tooth plates 44 to form an arc-shaped groove for buckling the swab 10. The clamped and fixed swab 10 rotates relatively to the elution tube 7, which is conducive to the elution work. The gear shaft 47 meshes with the sealing tooth plate 44 through the driving gear 48, and the power reversing shaft 49 makes the two gear shafts 47 rotate in opposite directions through the circular gear 50, thereby realizing the synchronous reverse sliding of the sealing tooth plate 44. The synchronous shaft 39, the power reversing shaft 49 and the other gear shaft 47 are connected through the synchronous wheel 4 51 and the synchronous belt 4 52 to ensure that the sealing stabilization mechanism and the side sealing mechanism operate synchronously. The tensioning roller 53 is used to maintain the tension of the synchronous belt 4 52.

[0081] When the side sealing mechanism starts to move (such as the closing plate 34 rises or falls), the synchronous shaft 39 will rotate accordingly, and the rotation of the synchronous shaft 39 is transmitted to the power reversing shaft 49 and another gear shaft 47 through the synchronous belt four 52 and the synchronous wheel four 51. The circular gear 50 on the power reversing shaft 49 is meshed with the circular gear 50 on the adjacent gear shaft 47, thereby realizing the opposite rotation of the two gear shafts 47. The driving gears 48 on the two gear shafts 47 are respectively meshed with the two sealing tooth plates 44. Therefore, when the gear shaft 47 rotates, it will drive the sealing tooth plates 44 to slide between the assembly side plates 43, and the sliding stabilizing strip 45 ensures the stability of the sealing tooth plates 44 during the sliding process.

[0082] When the closing plate 34 of the side closing mechanism rises, the synchronous belt 452 drives the power reversing shaft 49 and the gear shaft 47 to rotate, thereby causing the two sealing tooth plates 44 to slide away from each other and synchronously open the access opening 9. Conversely, when the closing plate 34 descends, the sealing tooth plates 44 slide toward each other, closing the access opening 9 and fixing the swab 10.

[0083] The synchronous operation of the sealing stabilization mechanism and the side sealing mechanism greatly improves the convenience of operation. When the sealing plate 34 of the side sealing mechanism rises, the sealing tooth plates 44 of the sealing stabilization mechanism slide away from each other synchronously, thereby simultaneously opening the storage slot 3 and the closed access opening 9, making it convenient for users to access the swab 10. This synchronous operation design reduces the user's operating steps and improves work efficiency. At the same time, due to the close cooperation between the sealing stabilization mechanism and the side sealing mechanism, the stability and reliability of the entire device during the access process are ensured.

[0084] The design of the sealing stabilization mechanism not only focuses on synchronous operation and operational convenience, but also fully considers the stability and safety of the structure. The sliding stabilization strip 45 ensures the stability of the sealing tooth plate 44 during the sliding process, avoiding operational errors caused by shaking or offset. The arc-shaped limit clamp 46 cooperates with the sealing tooth plate 44 to form an arc-shaped groove that snaps into the swab 10, which not only ensures the fixation of the swab 10, but also avoids damage caused by excessive squeezing. In addition, the design of the synchronous belt 4 52 and the tensioning roller 53 ensures the synchronous operation between the sealing stabilization mechanism and the side sealing mechanism, further improving the safety and stability of the entire device.

[0085] In another embodiment of the present invention, an eluent storage box 54 and a liquid pump 55 are fixedly installed in the elution processing chamber 2, the liquid inlet end of the liquid pump 55 is connected to the eluent storage box 54, and the liquid discharge end of the liquid pump 55 is installed with a liquid lifting tube 56, the liquid discharge end of the liquid lifting tube 56 extends to the outside of the box body 1 and is installed with a telescopic tube 57, the liquid discharge end of the telescopic tube 57 is fixedly connected to the sealing tooth plate 44 on the corresponding side, and the corresponding sealing tooth plate 44 is installed with a liquid discharge hole 58, the drainage hole 58 is connected with the telescopic tube 57, the drainage end of the drainage hole 58 corresponds to the top opening of the elution tube 7 when the sealing tooth plate 44 closes the access port 9, and is used for quantitatively supplying eluent into the elution tube 7, the top of the eluent storage box 54 is equipped with a filling pipe 59 located outside the box body 1, and the side bottom of the eluent storage box 54 is equipped with a sewage pipe 60 located outside the box body 1, and the sewage pipe 60 and the filling pipe 59 both have valves.

[0086] In the present embodiment, components such as an eluent storage box 54 and a liquid pump 55 are added to the elution treatment chamber 2 to realize the function of quantitatively supplying eluent to the elution tube 7. Specifically, the eluent storage box 54 is fixedly installed in the elution treatment chamber 2 for storing eluent. The liquid inlet end of the liquid pump 55 is connected to the eluent storage box 54, and the liquid discharge end is connected to the liquid discharge hole 58 on the sealing tooth plate 44 through the liquid lifting pipe 56 and the telescopic pipe 57. When the sealing tooth plate 44 closes the access port 9, the liquid discharge end of the liquid discharge hole 58 corresponds to the top opening of the elution tube 7. Through the operation of the liquid pump 55, the eluent can be drawn out from the eluent storage box 54, passed through the liquid lifting pipe 56 and the telescopic pipe 57, and finally quantitatively supplied to the elution tube 7. In addition, a filling pipe 59 is provided on the top of the eluent storage box 54 for filling the eluent into the box; a drain pipe 60 is provided on the bottom of the side for discharging waste liquid, and both the filling pipe 59 and the drain pipe 60 have valves for easy control.

[0087] The improvement in this embodiment realizes the automatic supply and quantitative control of the eluent. Through the coordinated use of the liquid pump 55, the liquid lifting pipe 56, the telescopic pipe 57 and the liquid discharge hole 58, the eluent can be accurately supplied to the eluent tube 7 without manual operation, which greatly improves the work efficiency and accuracy. At the same time, due to the large capacity of the eluent storage box 54, enough eluent can be stored to meet the needs of long-term use. In addition, the provision of the filling pipe 59 and the drain pipe 60 makes the filling of the eluent and the discharge of the waste liquid more convenient, and through the control of the valve, the safety and sanitation during the operation can be ensured.

[0088] Due to the flexible connection of the telescopic tube 57 , the position change of the sealing tooth plate 44 during the sliding process can be adapted to ensure that the eluent can be accurately supplied to the eluent tube 7 .

[0089] In summary, compared with the related art, the present device achieves full mixing of body fluid and eluent on the swab 10 by combining the elution processing mechanism and the rebound swing mechanism, without manual operation, thereby improving mixing efficiency and accuracy.

[0090] In the several embodiments provided in this application, it should be understood that the disclosed device can be implemented in other ways.

[0091] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the scope of protection of the invention. Obviously, the described embodiments are only some embodiments of the present invention, rather than all embodiments. Based on these embodiments, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention. Although the present invention has been described in detail with reference to the above embodiments, ordinary technicians in this field can still combine, add, delete or make other adjustments to the features in the various embodiments of the present invention according to the circumstances without conflict, without making creative work, so as to obtain different other technical solutions that do not deviate from the concept of the present invention in essence, and these technical solutions also belong to the scope of protection of the present invention.

Claims

1. An in vitro diagnostic kit, characterized in that: include: The box body has an inner cavity as an elution processing cavity, and a storage groove is provided on the side. The diagnostic kit body for diagnosis is stored in the storage groove. The elution processing cavity is provided with an elution processing mechanism for fully mixing the body fluid adhered to the swab with the eluent in the elution tube. The elution processing mechanism includes: A U-shaped bracket fixedly mounted on the inner wall of the bottom of the elution processing chamber; The tube-releasing tube installed on the top of the U-shaped bracket is rotatable, and the tube-releasing tube can be raised and lowered on the U-shaped bracket. The tube-releasing tube is filled with eluent, and a plurality of metal springs are fixedly installed in the tube-releasing tube for fixing the eluent tube when the eluent tube is placed. The swab is placed in the eluent tube and immersed in the eluent. A rebound swing mechanism is arranged in the elution processing chamber, and the rebound swing mechanism is used to drive the tube release tube to swing back and forth, so that the body fluid adhered to the swab is fully mixed with the eluent in the elution tube; and A test tube taking and placing lifting mechanism is arranged in the elution processing chamber, and the test tube taking and placing lifting mechanism is used to lift and lower the tube barrel, and is used to take and place the elution tube and the swab.

2. The in vitro diagnostic kit according to claim 1, characterized in that The top of the box body is provided with a take-in and put-out port which is in communication with the elution processing chamber and is used for taking and putting the elution tube and the swab cotton swab. The take-in and put-out port is located just above the tube putting tube cylinder.

3. The in vitro diagnostic kit according to claim 1, characterized in that The rebound type swing mechanism comprises a limit rotating cylinder, a spline cylinder, a skirt ring, a spline shaft, a torsion spring, a driven cam, a motor 1 and an active cam, the limit rotating cylinder is fixedly mounted on the bottom of the tube releasing cylinder, the bottom of the limit rotating cylinder contacts or separates from the top of the U-shaped bracket, the spline cylinder is rotatably mounted on the top of the U-shaped bracket, the skirt ring is fixedly mounted on the bottom end of the spline cylinder, the spline shaft is slidably penetrated and installed in the spline cylinder and the skirt ring, the top of the spline shaft is fixedly connected to the bottom of the tube releasing cylinder, the torsion spring is sleeved outside the spline cylinder, the two ends of the torsion spring are respectively inserted into the top and the skirt ring of the U-shaped bracket, the driven cam is fixedly sleeved on the tube releasing cylinder, the motor 1 is arranged on one side of the U-shaped bracket and fixedly connected to the inner wall of the elution processing chamber, the active cam is fixedly mounted on the output shaft of the motor 1, the active cam is located on one side of the driven cam, and the active cam and the driven cam have an intersection so that the driven cam is driven to rotate when the active cam rotates.

4. The in vitro diagnostic kit according to claim 3, characterized in that The bottom of the position-limiting rotating cylinder is inlaid with a plurality of rolling balls, and the plurality of rolling balls can roll along the top of the U-shaped bracket, and the plurality of rolling balls follow the lifting and lowering of the tube-releasing cylinder and the position-limiting rotating cylinder to contact or separate from the top of the U-shaped bracket.

5. The in vitro diagnostic kit according to claim 3, characterized in that: A stable shaft seat is rotatably sleeved on the output shaft of the motor 1, and the stable shaft seat is fixedly connected to the inner wall of the elution processing chamber.

6. The in vitro diagnostic kit according to claim 3, characterized in that The test tube placing and lifting mechanism includes a lifting ring, two winding shafts, and two lifting ropes. The lifting ring is rotatably mounted on the tube placing tube. The two winding shafts are rotatably installed in parallel in the elution processing chamber. The two winding shafts rotate synchronously. Both of the two winding shafts are located above the lifting ring. The two lifting ropes are respectively wound around the two winding shafts. The bottom ends of the two lifting ropes are fixedly connected to the top of the lifting ring.

7. The in vitro diagnostic kit according to claim 6, characterized in that The test tube placement and lifting mechanism also includes a rectangular lifting guide groove, a rectangular guide bar, two synchronous wheels one, a synchronous belt one, a motor two, two synchronous wheels two and a synchronous belt two. The rectangular lifting guide groove is opened on the inner walls on both sides corresponding to the elution processing chamber, the rectangular guide bar is slidably installed in the rectangular lifting guide groove, the rectangular guide bar is fixedly connected to the lifting ring, the two synchronous wheels one are respectively fixedly sleeved on the two winding shafts, the synchronous belt is set on the two synchronous wheels one, the motor two is fixedly installed in the elution processing chamber, the two synchronous wheels two are respectively fixedly sleeved on the output shaft of the motor two and any one of the winding shafts, and the synchronous belt two is sleeved on the two synchronous wheels two.

8. The in vitro diagnostic kit according to claim 7, characterized in that A controller is provided on one side of the box body, and the controller is connected to both the first motor and the second motor.

9. The in vitro diagnostic kit according to claim 7, characterized in that Both ends of the two winding shafts extend outside the box body, the distance between the top of the elution tube and the top of the box body is smaller than the lifting height of the tube release tube, and the distance of the rectangular guide bar sliding and lifting along the rectangular lifting guide groove is adapted to the lifting height of the tube release tube.

10. The in vitro diagnostic kit according to claim 1, characterized in that: A limiting screw is installed through the storage groove, the limiting screw presses the diagnostic kit body, both ends of the limiting screw extend out of the box body and are threadedly installed with locking nuts, and a handle is fixedly installed on the top of the box body.

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