Biological cell culture equipment for biological test
By designing cell culture equipment with multiple independent culture chambers and clamping mechanisms, the problem that existing equipment cannot culture multiple cells and sampling simultaneously and affects the growth environment is solved, and the simultaneous culture of multiple cells and the control of stable environment is achieved.
Patent Information
- Application Number
- CN202510054482.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-14
- Publication Date
- 2025-04-04
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing cell culture equipment cannot cultivate multiple different cells in one device at the same time, and opening the box door of the incubator at a large angle during sampling will affect the growth environment in the box.
A biological cell culture equipment for biological tests is designed, including a box and a frame, which is divided into multiple culture chambers. Each culture chamber is equipped with a lateral movement mechanism and lifting assembly, which can be independently opened and independently controlled by temperature. The clamping mechanism is used to pick up and place the Petri dishes without opening the equipment.
It realizes the simultaneous cultivation of different cell groups in multiple culture chambers. The independent temperature control and sealing structure ensure a stable culture environment. The clamping mechanism facilitates and quickly picks up and stores the culture dishes, avoiding affecting the culture environment.
Smart Images

Figure CN119752628A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of cell culture equipment, in particular to a biological cell culture equipment for biological experiments. Background Art
[0002] Batch cell culture is usually required in the laboratory. The cell culture unit uses a closed system for cell culture to avoid the risk of contamination. For example, covered culture dishes and other carriers are used to proliferate cells. In the cell culture unit, the culture medium usually needs to be refrigerated. Therefore, the culture medium container is placed in a cold room, and the culture medium is transferred from the culture medium container to the culture container via a pipeline. The culture dish is then placed in an incubator, and the appropriate temperature and humidity are set to culture the cells. The traditional incubator consists of a box body, a support frame, a temperature control device and a humidity control device. It plays an important role in pharmaceutical, biochemical, and medical fields. The incubator with this structure has the advantages of simple structure, easy use and low cost. It is currently the most widely used incubator for cell culture.
[0003] Currently, multiple culture dishes can be placed on a rack in an incubator, but the multiple culture dishes are in the same environment and are only suitable for one type of cell. It is impossible to culture multiple different cells in one device at the same time. Moreover, when sampling, the door of the incubator is opened at a large angle, which will also affect the growth environment inside the box. Summary of the invention
[0004] 1. Technical issues to be solved
[0005] In view of the deficiencies in the prior art, the present invention provides a biological cell culture device for biological experiments, which solves the problem that multiple culture dishes are in the same environment, are only suitable for one type of cell, and cannot culture multiple different cells in one device at the same time, and that the door of the incubator is opened at a large angle during sampling, which will also affect the growth environment inside the box.
[0006] (II) Technical solution
[0007] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: A biological cell culture device for biological experiments, comprising a box and a frame, wherein the frame is installed in the box through a bracket, a plurality of partitions are fixedly connected in the frame, and the plurality of partitions divide the frame into a plurality of culture chambers, and a plurality of evenly distributed placement tables are fixedly connected in the plurality of culture chambers, and a culture dish is arranged on the placement table;
[0008] Two slides are fixedly connected in the box body, and a transverse movement mechanism is commonly connected in the two slides. The transverse movement mechanism is provided with a base, and a vertical pipe is installed on the upper end of the base. A lifting assembly is installed in the vertical pipe, and a horizontal pipe is installed on the lifting assembly. A clamping mechanism is installed in the horizontal pipe. The clamping mechanism is used to clamp the culture dish on the placement table. An outlet is provided on one side of the box body, and a sealing assembly is installed at the outlet. The transverse movement mechanism can send the clamped culture dish out from the outlet on the box body, so that the technicians can use it conveniently.
[0009] The front end of the box body is provided with an opening, and the opening is hinged with two door panels.
[0010] Preferably, the transverse movement mechanism includes two guide rods, the rod walls of the two guide rods are sleeved with guide sleeves, the guide sleeves are fixed to the lower end of the base, the two slide seats are slidably connected with sliders, the two ends of the two guide rods are respectively fixedly connected to the opposite sides of the two sliders, a rack is fixedly connected between the two sliders, one side of the rack is meshed with a gear, the lower end of the base is fixedly connected to a first reduction motor through a support seat, the output end of the first reduction motor passes through the side wall of the base and is fixedly connected to one side of the gear, the side wall of the box is fixedly connected to a first electric push rod, and the output end of the first electric push rod is fixedly connected to one side of the slider.
[0011] Preferably, the lifting assembly includes a screw rod, the upper end of the vertical pipe is fixedly connected to a first motor, the output end of the first motor is coaxially fixedly connected to the upper end of the screw rod, the lower end of the screw rod is rotatably connected to a circular plate via a ball bearing, the circular plate is fixed at the pipe mouth of the vertical pipe, the lower end of the base is fixedly connected to a second reduction motor, the output end of the second reduction motor is fixedly connected to a main shaft, the main shaft is rotatably connected to the side wall of the base via a ball bearing, the upper end of the main shaft passes through the ball bearing and is fixedly connected to the lower end of the circular plate, a threaded sleeve is sleeved on the rod wall of the screw rod, the threaded sleeve is slidably connected in the vertical pipe, two strip holes are provided on the pipe wall of the vertical pipe, connecting blocks are sleeved in the two strip holes, one end of the connecting block is fixedly connected to a fixing plate, and the fixing plate is fixedly connected to one end of the horizontal pipe.
[0012] Preferably, the clamping mechanism comprises a mounting plate, the mounting plate is fixed in the transverse tube, two rotating shafts are rotatably connected in the transverse tube through rolling bearings, worm wheels are fixedly connected to the shaft walls of the two rotating shafts, a worm is meshed between the two worm wheels, a third reduction motor is fixedly connected in the transverse tube, and the output end of the third reduction motor passes through the side wall of the mounting plate and is fixedly connected to one end of the worm;
[0013] Two assembly holes are provided on the tube wall of the horizontal tube, and rectangular rods are fixedly connected in the two assembly holes. Two rectangular sleeves are sleeved on the rod wall of the rectangular rod. Two clamping plates are provided at the tube mouth of one end of the rectangular tube, and one end of the two clamping plates extends into the rectangular tube and is transversely fixedly connected with a support shaft. The two ends of the support shaft are respectively fixedly connected to the side walls of the two rectangular sleeves, and two transmission rods are fixedly connected to the shaft walls of the two rotating shafts. Rectangular holes are provided on the rod walls of the two transmission rods, and the rectangular holes are sleeved on the shaft wall of the support shaft.
[0014] Preferably, two reinforcing ribs are provided on one side of the clamping plate, and an anti-slip rubber pad is fixedly connected to the other side of the clamping plate. The end of the worm away from the third reduction motor is rotatably connected in the transverse tube through a bearing seat.
[0015] Preferably, a groove is provided on the side wall of the placement table, a curved surface structure matching with the culture dish is provided on one side of the groove, a support platform is provided in the groove, a slot matching with the bottom of the culture dish is provided on the side wall of the support platform, a plurality of air bags are embedded in the side wall of the slot through blind holes, and the upper ends of the air bags extend into the slot.
[0016] Preferably, an elastic strip is fixedly connected to the upper end of the placement table, a bending portion is provided at one end of the elastic strip, an assembly shaft is fixedly connected to one end of the bending portion, a rubber pressure roller is rotatably connected to the shaft wall of the assembly shaft, a limiting rod is provided below the bending portion, and the limiting rod is fixed to the upper end of the placement table.
[0017] Preferably, a rectangular plate is fixedly connected to the rear side of the frame, and the rectangular plate is a hollow structure. An air inlet pipe is arranged on one side of the rectangular plate, and a plurality of conduits are fixedly connected to the tube wall of the air inlet pipe, and an electric-controlled air valve and a temperature sensor are fixedly connected to the tube wall of the plurality of conduits, one end of the conduit is fixed to one side of the rectangular plate and extends to the hollow inside the rectangular plate, and a plurality of evenly distributed air outlet micropores are provided on the other side of the rectangular plate, and a plurality of partition bars are fixedly connected to the hollow structure of the rectangular plate, and the spacing between the plurality of partition bars corresponds to the positions of the plurality of partitions, and a hot air unit is fixedly connected to the box body, and the air outlet end of the hot air unit is connected to the air inlet pipe.
[0018] Preferably, a first baffle is fixedly connected to the culture chamber, and a side wall of the first baffle is provided with a plurality of evenly distributed first taking and releasing openings, and the first taking and releasing openings correspond to the position of the placing table. A second baffle is slidably connected to the side wall of the culture chamber through a slide groove, and the second baffle is in contact with one side of the first baffle and is provided with a plurality of evenly distributed second taking and releasing openings, and the size of the second taking and releasing openings is the same as that of the first taking and releasing openings. A limiting hole is provided at the lower end of the frame, and the lower end of the second baffle is slidably connected in the limiting hole. A second electric push rod is fixedly connected to the upper end of the frame, and an output end of the second electric push rod passes through the side wall of the frame and is fixedly connected to the upper end of the second baffle.
[0019] Preferably, the sealing assembly includes a sealing plate, the upper and lower ends of the sealing plate are slidably connected with a clamping strip, the clamping strip is fixed to the side wall of the box, one end of the sealing plate is provided with a connecting portion, the connecting portion is threadedly connected to a screw through a threaded hole, one side of the box is fixedly connected to a protective cover, a second motor is fixedly connected inside the protective cover, and the output end of the second motor is coaxially fixedly connected to one end of the screw.
[0020] (III) Beneficial effects
[0021] Compared with the prior art, the present invention provides a biological cell culture device for biological experiments, which has the following beneficial effects:
[0022] 1. When the present invention is in use, culture fluid and cell unit groups are added to the culture dish, and the culture dish cover can be placed on the placement table after it is covered. When there are many culture dishes, the door panel can be opened and the culture dishes can be directly placed in the culture chamber, and multiple culture chambers can also be opened and temperature-controlled independently, so that different cell unit groups that need to be cultured can be placed in multiple culture chambers. In addition, when there are already cultured cell unit groups in the culture chamber, the second motor is first started to drive the screw to rotate, and the rotation of the screw drives the connection part to move the sealing plate by using the threaded hole. When the sealing plate moves, it moves in the card strip, so that the sealing plate can be removed from the outlet, and then the clamping mechanism can be moved to the outlet to clamp the culture dish through the transverse movement mechanism and the lifting assembly, and then the transverse movement mechanism and the lifting assembly can be reset and moved into the box body and the culture dish can be placed on the corresponding placement table, so that different cell unit groups can be cultivated, and it is convenient to assist technicians in taking and placing culture dishes during cultivation.
[0023] 2. The lateral movement mechanism and the lifting assembly mechanism provided in the present invention can be used together to drive the clamping mechanism to move in the X-axis direction and the Y-axis direction, so as to correspond to the culture dishes on the placement table distributed in the matrix of the clamping. The lateral movement mechanism uses the first reduction motor as the power to drive the gear to rotate. When the gear rotates, it rolls on the rack, so that the base, the lifting assembly and the clamping mechanism can be driven in the opposite direction to move to the specified position. After reaching the specified position, the lifting mechanism uses the first motor as the power to drive the screw rod to rotate. When the screw rod rotates, the thread drives the threaded sleeve to move. When the threaded sleeve moves, the cross tube is moved through the connecting block and the fixed plate. When the cross tube moves, the clamping mechanism can be moved to the specified height. At this time, the second reduction motor drives the main shaft to rotate the vertical tube The vertical tube rotates, and the clamping mechanism faces the placement table. The first electric push rod drives the slider to move the transverse mechanism on the Z axis, so that the clamping mechanism facing the placement table can be extended into the culture chamber. The culture dish can be clamped by the clamping mechanism. Finally, the first electric push rod is reset, the second reduction motor is reversed to reset the vertical tube, the lifting mechanism moves the clamping mechanism to a position corresponding to the outlet height, and the first reduction motor drives the base to move the lifting assembly and the clamping mechanism to one side of the box. Finally, the culture dish is sent out of the box from the outlet after the sealing assembly is opened. Therefore, the culture dish can be taken out of the equipment without opening the equipment to observe the culture progress during the cultivation process, and the stable culture environment in the equipment is not affected.
[0024] 3. The clamping mechanism provided in the present invention, when in use, starts the third reduction motor to drive the worm to rotate the two worm wheels. When the two worm wheels rotate, they can drive the two transmission rods to swing relative to each other through the rotating shaft. When the transmission rods swing, they drive the support shaft and the sliding sleeve to slide on the rod wall of the rectangular rod. When the support shaft slides, it drives the clamping plate to move, so that the culture dish can be clamped, and the anti-slip rubber pad provided on the clamping plate can protect the culture dish and avoid scratching the surface of the culture dish during clamping.
[0025] 4. The rectangular plate provided in the present invention can form a sealing structure with the first baffle, the second baffle and the frame. The second electric push rod can drive the movably installed second baffle to move down to the lower dead point. When displacement occurs, the second pick-up and release port coincides with the first pick-up and release port. At this time, the clamping mechanism can extend into the culture chamber to clamp culture dishes at different positions. When the second baffle is at the upper dead point, the second baffle can cover the first pick-up and release port on the first baffle. In this way, the culture dish can be placed in a relatively sealed culture chamber. During the culture process, since the temperatures required for culturing different cell unit groups are also different, the air intake can be controlled by the opening angle of the electric control air valve. When the air intake is small, the amount of hot air delivered is also small. In this way, the temperature in the culture chamber can be controlled within a certain range and can be monitored by a temperature sensor. The temperature sensor can also be installed in the culture chamber, so that multiple cell unit groups can be cultured in different areas with different culture environments. BRIEF DESCRIPTION OF THE DRAWINGS
[0026] Figure 1 This is a schematic diagram of the structure of a biological cell culture device for biological experiments proposed by the present invention;
[0027] Figure 2 This is a schematic diagram of the internal structure of a box in a biological cell culture device for biological experiments proposed by the present invention;
[0028] Figure 3 This is a schematic structural diagram of a transverse movement mechanism, a lifting assembly, a clamping mechanism and a frame in a biological cell culture device for biological experiments proposed by the present invention;
[0029] Figure 4 This is a schematic structural diagram of a frame, a partition, a placement table and a second baffle in a biological cell culture device for biological experiments proposed by the present invention;
[0030] Figure 5 This is a schematic structural diagram of a frame, a partition, a first baffle and a second electric push rod in a biological cell culture device for biological experiments proposed by the present invention;
[0031] Figure 6 This is a schematic diagram of the structure of a rectangular plate, an air inlet pipe, an electric-controlled air valve, a temperature sensor and a hot air unit in a biological cell culture device for biological experiments proposed by the present invention;
[0032] Figure 7 This is a schematic structural diagram of a transverse movement mechanism, a lifting assembly and a clamping mechanism in a biological cell culture device for biological experiments proposed by the present invention;
[0033] Figure 8 This is a schematic diagram of the structure of a clamping mechanism in a biological cell culture device for biological experiments proposed by the present invention;
[0034] Fig. 9 This is a partial structural schematic diagram of a transverse movement mechanism in a biological cell culture device for biological experiments proposed by the present invention;
[0035] Fig.10 This is a schematic diagram of the structure of a placement table and a culture dish in a biological cell culture device for biological experiments proposed by the present invention;
[0036] Fig.11 The present invention is a schematic structural diagram of a sealing component in a biological cell culture device for biological experiments.
[0037] In the figure: 1, box body; 2, door panel; 3, card strip; 4, sealing plate; 5, protective cover; 6, first motor; 7, horizontal tube; 8, clamping plate; 9, frame; 10, placement table; 11, culture dish; 12, second baffle; 13, first electric push rod; 14, slide seat; 15, vertical tube; 16, base; 17, first reduction motor; 18, second reduction motor; 19, rack; 20, guide rod; 21, second pick-up and release port; 22, second electric push rod; 23, rectangular plate; 24, slider; 25, guide sleeve; 26, partition; 27, Limiting hole; 28. First baffle; 29. First loading and unloading port; 30. Air outlet micropore; 31. Barrier strip; 32. Electric control air valve; 33. Temperature sensor; 34. Hot air unit; 35. Screw; 36. Threaded sleeve; 37. Third reduction motor; 38. Worm gear; 39. Transmission rod; 40. Rectangular sleeve; 41. Rectangular rod; 42. Worm; 43. Support shaft; 44. Gear; 45. Groove; 46. Airbag; 47. Slot; 48. Rubber pressure roller; 49. Elastic strip; 50. Limiting rod; 51. Second motor; 52. Screw. DETAILED DESCRIPTION
[0038] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0039] Example 1: Refer to the attached Figure 1-Figure 11 A biological cell culture device for biological experiments, comprising a box 1 and a frame 9, the frame 9 is installed in the box 1 through a bracket, a plurality of partitions 26 are fixedly connected in the frame 9, the plurality of partitions 26 divide the frame 9 into a plurality of culture chambers, a plurality of evenly distributed placement tables 10 are fixedly connected in the plurality of culture chambers, a culture dish 11 is arranged on the placement table 10, a groove 45 is opened on the side wall of the placement table 10, a curved surface structure matching the culture dish 11 is arranged on one side of the groove 45, and the groove 45 is provided with The support platform has a side wall provided with a slot 47 matched with the bottom of the culture dish 11, and a plurality of air bags 46 are embedded in the side wall of the slot 47 through a blind hole, and the upper end of the air bag 46 extends into the slot 47. An elastic strip 49 is fixedly connected to the upper end of the placement platform 10, and a bending portion is provided at one end of the elastic strip 49, and an assembly shaft is fixedly connected to one end of the bending portion. A rubber pressure roller 48 is rotatably connected to the shaft wall of the assembly shaft, and a limit rod 50 is provided below the bending portion, and the limit rod 50 is fixed to the upper end of the placement platform 10;
[0040] Two slides 14 are fixedly connected in the box body 1, and a transverse movement mechanism is commonly connected in the two slides 14. The transverse movement mechanism is provided with a base 16. A vertical pipe 15 is installed at the upper end of the base 16. A lifting assembly is installed in the vertical pipe 15. A horizontal pipe 7 is installed on the lifting assembly. A clamping mechanism is installed in the horizontal pipe 7. The clamping mechanism is used to clamp the culture dish 11 on the placement table 10. An outlet is provided on one side of the box body 1, and a sealing assembly is installed at the outlet. The sealing assembly includes a sealing plate 4. The upper and lower ends of the sealing plate 4 are slidably connected with A clamping strip 3 is fixed to the side wall of the box body 1, a connecting portion is provided at one end of the sealing plate 4, a screw 52 is threadedly connected to the connecting portion through a threaded hole, a protective cover 5 is fixedly connected to one side of the box body 1, a second motor 51 is fixedly connected inside the protective cover 5, an output end of the second motor 51 is coaxially fixedly connected to one end of the screw 52, the transverse movement mechanism can deliver the clamped culture dish 11 from the outlet on the box body 1, so that the technicians can use it, an opening is provided at the front end of the box body 1, and two door panels 2 are hinged at the opening.
[0041] When the present invention is in use, culture fluid and cell unit groups are added to the culture dish 11, and the culture dish 11 can be placed on the placement table 10 after being covered with a cover plate. When there are many culture dishes 11, the door panel 2 can be opened and placed directly in the culture chamber, and multiple culture chambers can also be opened and temperature-controlled independently, so that different cell unit groups that need to be cultured can be placed in multiple culture chambers. In addition, when there are already cultured cell unit groups in the culture chamber, the second motor 51 is started first to drive the screw 52 to rotate, and the rotation of the screw 52 drives the connection part to move the sealing plate 4 using the threaded hole. When the sealing plate 4 moves, it moves in the card strip 3, so that the sealing plate 4 can be removed from the outlet, and then the clamping mechanism can be moved to the outlet to clamp the culture dish 11 through the transverse movement mechanism and the lifting assembly, and then the transverse movement mechanism and the lifting assembly can be reset and moved to the box 1 and the culture dish 11 can be placed on the corresponding placement table 10, so that different cell unit groups can be cultivated, and it is convenient to assist technicians in taking and placing the culture dish 11 during cultivation.
[0042] Embodiment 2: Based on embodiment 1, the difference is that;
[0043] Refer to the attached Figure 2-Figure 3 , Figure 7 and Fig. 9The transverse movement mechanism includes two guide rods 20, and the rod walls of the two guide rods 20 are both sleeved with guide sleeves 25, and the guide sleeves 25 are fixed to the lower end of the base 16. The two slide seats 14 are slidably connected with sliders 24. The two ends of the two guide rods 20 are respectively fixedly connected to the opposite sides of the two sliders 24. A rack 19 is fixedly connected between the two sliders 24, and a gear 44 is meshed on one side of the rack 19. The lower end of the base 16 is fixedly connected to the first reduction motor 17 through a support seat. The output end of the first reduction motor 17 passes through the side wall of the base 16 and is fixedly connected to one side of the gear 44. The side wall of the box body 1 is fixedly connected to the first electric push rod 13, and the output end of the first electric push rod 13 is fixedly connected to one side of the slider 24.
[0044] The lifting assembly includes a screw rod 35, and the upper end of the vertical pipe 15 is fixedly connected to the first motor 6, and the output end of the first motor 6 is coaxially fixedly connected to the upper end of the screw rod 35. The lower end of the screw rod 35 is rotatably connected to a circular plate through a ball bearing, and the circular plate is fixed at the pipe mouth of the vertical pipe 15. The lower end of the base 16 is fixedly connected to the second reduction motor 18, and the output end of the second reduction motor 18 is fixedly connected to the main shaft, and the main shaft is rotatably connected to the side wall of the base 16 through a ball bearing. The upper end of the main shaft passes through the ball bearing and is fixedly connected to the lower end of the circular plate. A threaded sleeve 36 is sleeved on the rod wall of the screw rod 35, and the threaded sleeve 36 is slidably connected in the vertical pipe 15. Two strip holes are opened on the pipe wall of the vertical pipe 15, and connecting blocks are sleeved in the two strip holes. One end of the connecting block is fixedly connected to a fixing plate, and the fixing plate is fixedly connected to one end of the horizontal pipe 7.
[0045] The lateral movement mechanism and the lifting assembly mechanism provided in the present invention can be used together to drive the clamping mechanism to move in the X-axis direction and the Y-axis direction, so that the culture dish 11 on the placement table 10 with a matrix distribution can be clamped. The working of the lateral movement mechanism is to use the first reduction motor 17 as the power to drive the gear 44 to rotate. When the gear 44 rotates, it rolls on the rack 19, so that the base 16 and the lifting assembly and the clamping mechanism can be driven in the opposite direction to move to the specified position. After reaching the specified position, the lifting mechanism uses the first motor 6 as the power to drive the screw rod 35 to rotate. When the screw rod 35 rotates, the thread drives the threaded sleeve 36 to move. When the threaded sleeve 36 moves, the cross tube 7 is moved through the connecting block and the fixed plate. When the cross tube 7 moves, the clamping mechanism can be moved to the specified height. At this time, the second reduction motor 18 drives the main shaft to rotate the vertical tube 15 After the vertical tube 15 rotates, the clamping mechanism can be directed toward the placement table 10, and then the first electric push rod 13 drives the slider 24 to move the transverse mechanism on the Z axis, so that the clamping mechanism directed toward the placement table 10 can be extended into the culture chamber, and then the culture dish 11 can be clamped by the clamping mechanism, and finally the first electric push rod 13 is reset, the second reduction motor 18 is reversed to reset the vertical tube 15, the lifting mechanism moves the clamping mechanism to a position corresponding to the outlet height, and the first reduction motor 17 drives the base 16 to move the lifting assembly and the clamping mechanism to one side of the box body 1, and finally the culture dish 11 is sent out of the box body 1 from the outlet after the sealing assembly is opened, so that the culture progress of the cells can be observed without opening the equipment to take out the culture dish 11 during the cultivation process, and the stable culture environment in the equipment is not affected.
[0046] Embodiment 3: Based on embodiment 1, the difference is that;
[0047] Refer to the attached Figure 3 and Figure 8 The clamping mechanism includes a mounting plate, which is fixed in the transverse tube 7. Two rotating shafts are rotatably connected in the transverse tube 7 through rolling bearings. Worm wheels 38 are fixedly connected to the shaft walls of the two rotating shafts. A worm 42 is meshed between the two worm wheels 38. A third reduction motor 37 is fixedly connected in the transverse tube 7. The output end of the third reduction motor 37 passes through the side wall of the mounting plate and is fixedly connected to one end of the worm 42.
[0048] Two assembly holes are provided on the tube wall of the cross tube 7, and rectangular rods 41 are fixedly connected in the two assembly holes. Two rectangular sleeves 40 are sleeved on the rod wall of the rectangular rod 41. Two clamping plates 8 are provided at the tube mouth of one end of the rectangular tube. One end of the two clamping plates 8 extends into the rectangular tube and is transversely fixedly connected with a support shaft 43. The two ends of the support shaft 43 are respectively fixedly connected to the side walls of the two rectangular sleeves 40. Two transmission rods 39 are fixedly connected to the shaft walls of the two rotating shafts. Rectangular holes are provided on the rod walls of the two transmission rods 39, and the rectangular holes are sleeved on the shaft walls of the support shaft 43. Two reinforcing ribs are provided on one side of the clamping plate 8, and an anti-slip rubber pad is fixedly connected to the other side of the clamping plate 8. The end of the worm 42 away from the third reduction motor 37 is rotatably connected to the cross tube 7 through a bearing seat.
[0049] The clamping mechanism provided in the present invention, when in use, starts the third reduction motor 37 to drive the worm 42 to rotate the two worm wheels 38. When the two worm wheels 38 rotate, they can drive the two transmission rods 39 to swing relative to each other through the rotating shaft. When the transmission rod 39 swings, it drives the support shaft 43 and the sliding sleeve to slide on the rod wall of the rectangular rod 41. When the support shaft 43 slides, it drives the clamping plate 8 to move, so that the culture dish 11 can be clamped, and the anti-slip rubber pad provided on the clamping plate 8 can protect the culture dish 11 and avoid scratching the surface of the culture dish 11 during clamping.
[0050] Embodiment 4: Based on embodiment 1, the difference is that;
[0051] Refer to the attached Figure 2-Figure 6 A rectangular plate 23 is fixedly connected to the rear side of the frame 9. The rectangular plate 23 is a hollow structure. An air inlet pipe is arranged on one side of the rectangular plate 23. A plurality of conduits are fixedly connected to the pipe wall of the air inlet pipe. An electric-controlled air valve 32 and a temperature sensor 33 are fixedly connected to the pipe wall of the plurality of conduits. One end of the conduit is fixed to one side of the rectangular plate 23 and extends to the hollow inside the rectangular plate 23. A plurality of evenly distributed air outlet micropores 30 are provided on the other side of the rectangular plate 23. A plurality of baffle bars 31 are fixedly connected to the hollow structure of the rectangular plate 23. The spacing between the plurality of baffle bars 31 corresponds to the position of the plurality of baffle plates 26. A hot air unit 34 is fixedly connected to the box body 1. The air outlet end of the hot air unit 34 is connected to the air inlet pipe.
[0052] A first baffle 28 is fixedly connected in the culture chamber, and a plurality of evenly distributed first access openings 29 are provided on the side wall of the first baffle 28, and the first access openings 29 correspond to the position of the placement table 10. A second baffle 12 is slidably connected to the side wall of the culture chamber through a slide groove, and the second baffle 12 contacts one side of the first baffle 28 and is provided with a plurality of evenly distributed second access openings 21, and the size of the second access openings 21 is the same as that of the first access openings 29. A limiting hole 27 is provided at the lower end of the frame 9, and the lower end of the second baffle 12 is slidably connected in the limiting hole 27, and a second electric push rod 22 is fixedly connected to the upper end of the frame 9, and the output end of the second electric push rod 22 passes through the side wall of the frame 9 and is fixedly connected to the upper end of the second baffle 12.
[0053] The rectangular plate 23 provided in the present invention can form a sealing structure with the first baffle 28, the second baffle 12 and the frame 9. The second electric push rod 22 can drive the movably installed second baffle 12 to move down to the lower dead point. When displacement occurs, the second pick-up and release port 21 coincides with the first pick-up and release port 29. At this time, the clamping mechanism can extend into the culture chamber to clamp the culture dish 11 at different positions. When the second baffle 12 is at the upper dead point, the second baffle 12 can cover the first pick-up and release port 29 on the first baffle 28. In this way, the culture dish 11 can be placed in a relatively sealed culture chamber. During the culture process, since the temperatures required for culturing different cell unit groups are also different, the air intake can be controlled by the opening angle of the electric control valve. When the air intake is small, the amount of hot air delivered is also small. In this way, the temperature in the culture chamber can be controlled within a certain range and can be monitored by the temperature sensor 33. The temperature sensor 33 can also be installed in the culture chamber, so that multiple cell unit groups can be cultured in different areas with different cultivation environments.
[0054] It should be noted that the term "comprises" or any other variation thereof is intended to cover non-exclusive inclusion, so that a process, method, article, or device that includes a series of elements includes not only those elements, but also includes other elements that are not explicitly listed, or also includes elements inherent to such process, method, article, or device. In the absence of further restrictions, an element defined by the sentence "comprises a ..." does not exclude the presence of other identical elements in the process, method, article, or device that includes the element.
[0055] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A biological cell culture device for biological experiments, comprising a box (1) and a frame (9), characterized in that: The frame (9) is installed in the box (1) through a bracket, and a plurality of partitions (26) are fixedly connected in the frame (9), and the plurality of partitions (26) divide the frame (9) into a plurality of culture chambers, and a plurality of evenly distributed placement tables (10) are fixedly connected in the plurality of culture chambers, and a culture dish (11) is arranged on the placement table (10); Two slide seats (14) are fixedly connected in the box body (1), and a transverse movement mechanism is commonly connected in the two slide seats (14). The transverse movement mechanism is provided with a base (16). A vertical pipe (15) is installed at the upper end of the base (16). A lifting assembly is installed in the vertical pipe (15). A horizontal pipe (7) is installed on the lifting assembly. A clamping mechanism is installed in the horizontal pipe (7). The clamping mechanism is used to clamp a culture dish (11) on the placement table (10). An outlet is provided on one side of the box body (1), and a sealing assembly is installed at the outlet. The transverse movement mechanism can send the clamped culture dish (11) out of the outlet on the box body (1) to facilitate the technician to use it. The front end of the box body (1) is provided with an opening, and two door panels (2) are hingedly connected to the opening.
2. A biological cell culture device for biological experiments according to claim 1, characterized in that: The transverse movement mechanism comprises two guide rods (20), the rod walls of the two guide rods (20) are sleeved with guide sleeves (25), the guide sleeves (25) are fixed to the lower end of the base (16), the two slide seats (14) are slidably connected with sliders (24), the two ends of the two guide rods (20) are respectively fixedly connected to the opposite sides of the two sliders (24), a rack (19) is fixedly connected between the two sliders (24), one side of the rack (19) is meshed with a gear (44), the lower end of the base (16) is fixedly connected with a first reduction motor (17) through a support seat, the output end of the first reduction motor (17) passes through the side wall of the base (16) and is fixedly connected to one side of the gear (44), the side wall of the box body (1) is fixedly connected with a first electric push rod (13), the output end of the first electric push rod (13) is fixedly connected to one side of the slider (24).
3. The biological cell culture device for biological experiments according to claim 1, characterized in that: The lifting assembly comprises a screw rod (35), the upper end of the vertical pipe (15) is fixedly connected to a first motor (6), the output end of the first motor (6) is coaxially fixedly connected to the upper end of the screw rod (35), the lower end of the screw rod (35) is rotatably connected to a circular plate via a ball bearing, the circular plate is fixed at the pipe mouth of the vertical pipe (15), the lower end of the base (16) is fixedly connected to a second reduction motor (18), the output end of the second reduction motor (18) is fixedly connected to a main shaft, and the The main shaft is rotatably connected to the side wall of the base (16) through a ball bearing, the upper end of the main shaft passes through the ball bearing and is fixedly connected to the lower end of the circular plate, a threaded sleeve (36) is sleeved on the rod wall of the screw rod (35), and the threaded sleeve (36) is slidably connected in the vertical pipe (15), and two strip holes are opened on the tube wall of the vertical pipe (15), and connecting blocks are sleeved in the two strip holes, and one end of the connecting block is fixedly connected to a fixing plate, and the fixing plate is fixedly connected to one end of the horizontal pipe (7).
4. The biological cell culture device for biological experiments according to claim 1, characterized in that: The clamping mechanism comprises a mounting plate, the mounting plate is fixed in the transverse tube (7), two rotating shafts are rotatably connected in the transverse tube (7) via rolling bearings, worm wheels (38) are fixedly connected to the shaft walls of the two rotating shafts, a worm (42) is meshed between the two worm wheels (38), a third reduction motor (37) is fixedly connected in the transverse tube (7), an output end of the third reduction motor (37) passes through the side wall of the mounting plate and is fixedly connected to one end of the worm (42); Two assembly holes are provided on the tube wall of the transverse tube (7), and rectangular rods (41) are fixedly connected in the two assembly holes. Two rectangular sleeves (40) are sleeved on the rod wall of the rectangular rod (41). Two clamping plates (8) are provided at the tube opening at one end of the rectangular tube. One end of the two clamping plates (8) extends into the rectangular tube and is transversely fixedly connected to a support shaft (43). The two ends of the support shaft (43) are respectively fixedly connected to the side walls of the two rectangular sleeves (40). Two transmission rods (39) are fixedly connected to the shaft walls of the two rotating shafts. Rectangular holes are provided on the rod walls of the two transmission rods (39), and the rectangular holes are sleeved on the shaft wall of the support shaft (43).
5. A biological cell culture device for biological experiments according to claim 4, characterized in that: Two reinforcing ribs are provided on one side of the clamping plate (8), and an anti-slip rubber pad is fixedly connected to the other side of the clamping plate (8). The end of the worm (42) away from the third reduction motor (37) is rotatably connected to the transverse tube (7) through a bearing seat.
6. The biological cell culture device for biological experiments according to claim 1, characterized in that: The side wall of the placement table (10) is provided with a groove (45), one side of the groove (45) is provided with a curved surface structure matching with the culture dish (11), the groove (45) is provided with a support table, the side wall of the support table is provided with a slot (47) matching with the bottom of the culture dish (11), the side wall of the slot (47) is embedded with a plurality of air bags (46) through blind holes, and the upper ends of the air bags (46) extend into the slot (47).
7. The biological cell culture device for biological experiments according to claim 1, characterized in that: The upper end of the placement platform (10) is fixedly connected to an elastic strip (49), one end of the elastic strip (49) is provided with a bending portion, one end of the bending portion is fixedly connected to an assembly shaft, a rubber pressure roller (48) is rotatably connected to the shaft wall of the assembly shaft, a limit rod (50) is provided below the bending portion, and the limit rod (50) is fixed to the upper end of the placement platform (10).
8. The biological cell culture device for biological experiments according to claim 1, characterized in that: A rectangular plate (23) is fixedly connected to the rear side of the frame (9); the rectangular plate (23) is a hollow structure; an air inlet pipe is arranged on one side of the rectangular plate (23); a plurality of conduits are fixedly connected to the pipe wall of the air inlet pipe; an electric-controlled air valve (32) and a temperature sensor (33) are fixedly connected to the pipe wall of the plurality of conduits; one end of the conduit is fixed to one side of the rectangular plate (23) and extends to the hollow inside the rectangular plate (23); a plurality of evenly distributed air outlet micropores (30) are provided on the other side of the rectangular plate (23); a plurality of baffle bars (31) are fixedly connected to the hollow structure of the rectangular plate (23); the spacing between the plurality of baffle bars (31) corresponds to the position of the plurality of baffle plates (26); a hot air unit (34) is fixedly connected to the inside of the box (1); the air outlet end of the hot air unit (34) is connected to the air inlet pipe.
9. The biological cell culture device for biological experiments according to claim 1, characterized in that: A first baffle (28) is fixedly connected in the culture chamber, and a plurality of evenly distributed first access openings (29) are provided on the side wall of the first baffle (28), and the first access openings (29) correspond to the position of the placement table (10). A second baffle (12) is slidably connected to the side wall of the culture chamber through a slide groove, and the second baffle (12) contacts one side of the first baffle (28) and is provided with a plurality of evenly distributed second access openings (21), and the size of the second access openings (21) is the same as that of the first access openings (29). A limiting hole (27) is provided at the lower end of the frame (9), and the lower end of the second baffle (12) is slidably connected in the limiting hole (27). A second electric push rod (22) is fixedly connected to the upper end of the frame (9), and the output end of the second electric push rod (22) passes through the side wall of the frame (9) and is fixedly connected to the upper end of the second baffle (12).
10. The biological cell culture device for biological experiments according to claim 1, characterized in that: The sealing assembly comprises a sealing plate (4), the upper and lower ends of the sealing plate (4) are slidably connected to a clamping strip (3), the clamping strip (3) is fixed to the side wall of the box body (1), one end of the sealing plate (4) is provided with a connecting portion, the connecting portion is threadedly connected to a screw rod (52) through a threaded hole, one side of the box body (1) is fixedly connected to a protective cover (5), a second motor (51) is fixedly connected inside the protective cover (5), and an output end of the second motor (51) is fixedly connected to one end of the screw rod (52) coaxially.
Citation Information
Cited By
Intelligent biochemical culture equipment
CN121610338A