A DOT peripheral diffusion retinal contrast adjustment lens and a manufacturing method thereof

Abstract

The present invention discloses a DOT peripheral diffusion retinal contrast adjustment lens, comprising a central optical area and a peripheral diffusion area. The central optical area corrects the refractive error of central vision; the peripheral diffusion area uses optical microstructures including microlenses, microprisms, etc. to adjust the peripheral retinal contrast, which can be adjusted differentially; the transition area can adopt a gradual design to ensure smooth transition of light. The manufacturing method covers accurately obtaining refractive data, manufacturing basic lenses, constructing microstructures, and generating transition areas. According to clinical research and actual case verification, the lens can effectively slow down the development of myopia in children and optimize the visual function of adults. It has broad application prospects in the field of myopia prevention and control and visual improvement, bringing new hope and choices to relevant patients.

Description

Technical Field

[0001] The present invention relates to the technical field of optical lenses, and in particular to a DOT peripheral diffusion retinal contrast adjustment lens and a manufacturing method thereof.

[0002] DOT lenses, or dot diffusion microlenses, are a type of lens used to prevent and control myopia. Background Art

[0004] From a genetic perspective, some people have conditions such as mutations in the opsin gene array in L / M cones, which can lead to abnormally increased retinal contrast and subsequently cause myopia. This genetic factor has a more significant impact on the development of myopia, especially in children whose parents or one parent is myopic. As described in this PPT, genetic studies have found that patients with pathological high myopia have gene mutations, which lead to changes in the opsin content in cones, making the retinal contrast overly sensitive, and ultimately leading to a crazy growth of the eye axis.

[0005] Environmental factors cannot be ignored either. Changes in the light environment in modern life, such as the excessive stimulation of long-wave red light L and short-wave blue light S relative to medium-wave M and green, may lead to excessive visual contrast, excessive optical stimulation to the retina, and cause the elongation of the eye axis, ultimately leading to the occurrence and development of myopia. At the same time, as mentioned in the PPT, children who participate in more high-contrast activities such as using electronic screens, reading, and studying are more likely to develop myopia than children who do more outdoor activities. This further illustrates the impact of environmental factors on the formation of myopia.

[0006] In the research process of myopia prevention and control technology, traditional myopia prevention and control glasses are mainly developed based on the theory of human eye adjustment and convergence compensation. However, after compensation adjustment, these glasses often relax the far and near adjustment and the convergence adjustment, causing the wearer to have blurred vision in scenes such as indoor activities. They cannot effectively solve the blur problem related to convergence, nor can they intervene in the fundamental mechanism of myopia development.

[0007] As the research on the formation mechanism of myopia continues to deepen, the retinal contrast theory has gradually attracted attention. This theory believes that excessive stimulation of the retina by high contrast is closely related to excessive stimulation of eye growth, which has promoted the development of DOT peripheral diffuse retinal contrast adjustment lens technology. Summary of the invention

[0008] The purpose of the present invention is to solve the shortcomings of the prior art and to propose a DOT peripheral diffusion retinal contrast adjustment lens, comprising a central optical area for correcting central vision ametropia, a peripheral diffusion area surrounding the central optical area and adjusting the peripheral retinal contrast through an optical microstructure.

[0009] Preferably, the central optical area can be customized according to the wearer's myopia, hyperopia or astigmatism to ensure clear correction of central vision.

[0010] Preferably, the optical microstructure of the peripheral diffusion area includes a microlens having a specific range of curvature radius, and adjusting the light distribution and contrast of the peripheral retina by refraction of light.

[0011] Preferably, the optical microstructure of the peripheral diffusion area is a plurality of micro-cavities arranged on the mirror surface for reflecting and filtering the light beam.

[0012] Preferably, the peripheral diffusion area can achieve differentiated adjustment of light contrast at different positions according to the visual needs of different areas of the peripheral retina, including local contrast enhancement and local contrast reduction functions.

[0013] Preferably, the central optical area and the peripheral diffusion area cooperate with each other in optical performance. The central optical area ensures clear imaging of central vision, and the peripheral diffusion area optimizes peripheral retinal visual function, thereby jointly improving the overall visual quality of the wearer.

[0014] A method for manufacturing the DOT peripheral diffuse retinal contrast adjustment lens comprises: according to the refractive data of the wearer's central vision, using conventional lens processing technology to manufacture a basic lens with a central optical area that meets the standards.

[0015] Preferably, it also includes using micromachining technology to construct an optical microstructure of the peripheral diffusion area around the base lens, strictly controlling various parameters of the microstructure, and then using special coating or surface treatment technology to generate a transition area to ensure the consistency and stability of the overall optical performance of the lens and meet the design requirements of peripheral retinal contrast adjustment, wherein the micromachining technology includes but is not limited to photolithography and electron beam etching technology.

[0016] Compared with the existing technology, the beneficial effects of the present invention are: the DOT peripheral diffusion retinal contrast adjustment lens of the present invention provides an innovative, efficient, safe and broadly applicable method for myopia prevention and control and visual function optimization through unique structural design, scientific manufacturing methods, sufficient clinical verification and diversified clinical application expansion. Specifically, the visual light passing through the central optical zone can be directly refracted and irradiated on the fovea of ​​the retina to form a clear visual image, and the light in the peripheral optical zone is diffused through the fovea, and only a faint light enters the outside of the retinal macular area. Compared with the light passing through the central optical zone, the contrast is increased. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic diagram of the overall structure of a DOT peripheral diffuse retinal contrast adjustment lens proposed by the present invention (lens front view);

[0018] Figure 2 This is a schematic diagram of the imaging principle of a DOT peripheral diffusion retinal contrast adjustment lens proposed by the present invention. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0020] Referring to the figure, this embodiment provides a DOT peripheral diffusion retinal contrast adjustment lens to solve the deficiencies of the prior art in myopia prevention and control and visual function optimization. Specifically, this embodiment provides a DOT peripheral diffusion retinal contrast adjustment lens, including a central optical area for correcting central vision ametropia, a peripheral diffusion area surrounding the central optical area and adjusting the peripheral retinal contrast through an optical microstructure.

[0021] Furthermore, the central optical area can be customized according to the wearer's myopia, hyperopia or astigmatism to ensure clear correction of central vision.

[0022] Furthermore, the optical microstructure of the peripheral diffusion area includes a microlens having a specific range of curvature radius, which adjusts the light distribution and contrast of the peripheral retina by refraction of light.

[0023] Furthermore, the optical microstructure of the peripheral diffusion area is a plurality of micro-cavities arranged on the mirror surface for reflecting and filtering the light beam.

[0024] Furthermore, the peripheral diffusion area can achieve differentiated adjustment of light contrast at different locations according to the visual needs of different areas of the peripheral retina, including local contrast enhancement and local contrast reduction functions.

[0025] Furthermore, the central optical area and the peripheral diffusion area cooperate with each other in optical performance. The central optical area ensures clear imaging of central vision, and the peripheral diffusion area optimizes the peripheral retinal visual function, thereby jointly improving the overall visual quality of the wearer.

[0026] A method for manufacturing the DOT peripheral diffuse retinal contrast adjustment lens is also provided, comprising: using conventional lens processing technology to manufacture a basic lens with a standard central optical area according to the refractive data of the wearer's central vision.

[0027] Furthermore, it also includes the use of micro-machining technology to construct an optical microstructure of the peripheral diffusion area around the base lens, strictly controlling the various parameters of the micro-structure, and then using special coating or surface treatment technology to generate a transition area to ensure the consistency and stability of the overall optical performance of the lens and meet the design requirements of peripheral retinal contrast adjustment. Micro-machining technology includes but is not limited to photolithography and electron beam etching technology.

[0028] When implementing the above embodiment, the following aspects need to be noted: 1. Lens structure design: the central optical area and the peripheral diffusion area;

[0029] Central optical area: This area is mainly responsible for correcting the wearer's central vision ametropia, including myopia, hyperopia and astigmatism. By accurately measuring the wearer's eye refraction data, using conventional high-quality optical lens materials such as resin, and applying advanced grinding, polishing and other processing techniques, the central optical area that meets individual needs is customized. This area can ensure that the wearer obtains clear and sharp vision when focusing on the central field of vision, such as reading, looking at a computer screen or observing distant objects.

[0030] Peripheral diffusion zone: Surrounding the central optical zone, it is the core innovation of the lens of this invention. This zone uses special optical microstructures to adjust the contrast of the peripheral retina.

[0031] 2. Optical microstructure type: generally, micro-holes are arranged in the peripheral diffusion area to form micro-lenses or micro-prisms;

[0032] Microlens: Microlens has a specially designed curvature radius range. When light passes through, it changes the propagation direction and distribution of light according to the principle of refraction. In the peripheral retinal area where the contrast needs to be reduced, the microlens scatters the light more widely, distributes the light evenly, reduces the local light intensity difference, and thus reduces the contrast; in the area where the contrast needs to be enhanced, the curvature of the microlens and other parameters are adjusted to make the light in the target area relatively concentrated, thereby increasing the contrast difference with the surrounding area.

[0033] Microprism: The angle and shape parameters of the microprism are carefully designed to refract the incident light. By properly setting the angle and arrangement of the microprism, precise control of peripheral light is achieved, and the intensity of light received by different areas of the peripheral retina is adjusted, thereby changing the contrast. For example, the refraction of light is increased or decreased in certain specific angles to achieve the purpose of adjusting the contrast.

[0034] Differentiated adjustment function: The peripheral diffusion area can achieve differentiated adjustment of light contrast according to the visual needs of different areas of the peripheral retina. For example, in different positions or different viewing angles of the retina, the contrast can be adjusted in a targeted manner according to the visual function characteristics and the possible visual environment. In areas with high visual sensitivity, the contrast is appropriately enhanced to improve the perception of object details and movement; in areas prone to visual fatigue or interference, the contrast is reduced to reduce excessive stimulation of visual information and improve visual comfort.

[0035] In addition, a transition area can be set: the transition area is located between the central optical area and the peripheral diffusion area, and adopts a gradient optical design. Through special material formulation and process treatment, the refractive index of the transition area gradually and smoothly transitions from the central optical area to the peripheral diffusion area. In the process of light propagation, this gradient design ensures that the change in the propagation direction and the change in optical properties of light when it transitions from the center to the periphery are continuous and natural, effectively avoiding visual abruptness, aberration, halo and other problems caused by sudden changes in optical properties. This allows the wearer to enjoy a seamless, natural and smooth visual experience during the process of sight transfer, whether looking from the central field of view to the peripheral field of view, or vice versa, improving the overall visual quality and wearing comfort.

[0036] Method of manufacturing lenses

[0037] First, the refractive data of the wearer's central vision is accurately obtained, which is the basis of the manufacturing process. High-precision optometry equipment, such as computer ophthalmometers and comprehensive ophthalmometers, is used to accurately measure the wearer's myopia, hyperopia, astigmatism, axis position and other parameters, and record detailed data.

[0038] Based on the refractive data obtained, conventional lens processing technology is used to manufacture basic lenses that meet the standards in the central optical area. This process involves the selection of lens materials, usually resin materials with excellent optical properties, strong impact resistance and light weight. Through advanced CNC grinding equipment, according to pre-set procedures, the lenses are precisely ground to match their curvature with the wearer's refractive power. Then, a fine polishing process is used to remove tiny flaws and roughness on the lens surface, improve the transparency and optical clarity of the lens, and ensure that the central optical area can provide high-quality central vision correction effects.

[0039] After the basic lens is manufactured, micromachining technology is used to construct an optical microstructure of the peripheral diffusion area around it. Among them, photolithography technology can transfer the designed microstructure pattern to the photoresist layer on the surface of the lens by making a high-precision photolithography mask, and then accurately etch the microstructure onto the lens surface through process steps such as development and etching; electron beam etching technology uses a focused electron beam to etch directly on the lens material, which can achieve higher resolution and finer microstructure processing. In the process of constructing the optical microstructure, various parameters of the microstructure are strictly controlled, such as the radius of curvature of the microlens, the angle and size of the microprism, the grating constant, groove depth and duty cycle of the diffraction grating, etc., to ensure that these parameters meet the design requirements to achieve the expected peripheral retinal contrast adjustment function.

[0040] Finally, a special coating or surface treatment process is used to generate the transition zone. By depositing one or more layers of thin film materials with gradient refractive index characteristics on the surface of the lens, such as oxide film, fluoride film, etc., the refractive index of the transition zone gradually changes from the central optical area to the peripheral diffusion area. At the same time, the surface treatment process can also improve the wear resistance, anti-fouling and anti-reflection properties of the lens, and increase the service life and optical performance stability of the lens. Throughout the manufacturing process, quality control standards are strictly implemented, and each lens is subjected to comprehensive optical performance testing, including refractive power accuracy, optical uniformity, contrast adjustment effect, aberration control and other indicators. To ensure that every piece of DOT peripheral diffusion retinal contrast adjustment lens shipped out of the factory can meet high quality standards and provide wearers with safe, effective and comfortable vision correction and myopia prevention and control solutions.

[0041] Implementation case 1: Children's myopia prevention and control application

[0042] Lens fitting and wearing: An 8-year-old myopic child was selected, and professional optometry determined that his myopia was -2.50D, astigmatism was -0.50D, and the axis position was 175°. Based on these refractive data, the DOT peripheral diffusion retinal contrast adjustment lens of the present invention was customized. After the lens was made, a professional optometrist tried it on the child and adjusted the frame appropriately according to the child's facial features and wearing comfort to ensure that the optical center of the lens was aligned with the child's pupil center to obtain the best visual correction effect.

[0043] Observation of visual effects and myopia prevention and control effects: In the initial stage after wearing the lenses, children clearly felt that their central vision was clear, and the visual clarity in daily learning activities such as reading books and watching blackboards was significantly improved. After wearing them for one month, parents and teachers reported that the children's visual performance in indoor activities was more stable, and compared with wearing traditional myopia glasses in the past, the blurred vision caused by the relaxation of vergence and accommodation was significantly reduced. This is because the peripheral diffusion area of ​​the lens of the present invention effectively adjusts the peripheral retinal contrast, reduces the blur associated with vergence, and thus improves the overall visual contrast signal.

[0044] Long-term tracking and data analysis: The child was followed up for 12 months, and a comprehensive eye examination was performed every 3 months, including axial length measurement, refractive power examination, vision test, etc. Data after 12 months showed that the growth rate of the child's axial length was significantly slower than that of his peers wearing traditional myopia glasses. Before wearing the lenses of the present invention, the child's axial length was 23.85mm, which increased to 24.08mm after 12 months, an increase of 0.23mm; according to clinical research data, the average axial length of children wearing traditional single-vision lenses increased by about 0.40mm during the same period. At the same time, in terms of refractive power, the degree of myopia only increased by -0.25D, while the degree of myopia under traditional myopia prevention and control methods increased by an average of about -0.50D during the same period. This shows that the lenses of the present invention have a significant effect in slowing the development of myopia in children.

[0045] Implementation case 2: Adult visual function optimization application

[0046] Occupational requirements and lens selection: A 35-year-old adult who works in computer design and faces computer screens for a long time often suffers from eye fatigue, poor visual concentration and other problems. After examination, his binocular vision is normal, but there is a slight adjustment lag and imbalance in peripheral retinal contrast perception. In order to improve his visual function, the DOT peripheral diffuse retinal contrast adjustment lens of the present invention is selected.

[0047] Experience and improvement in work scenarios: In daily work after wearing the lenses, the adult found that the eye fatigue was significantly reduced when staring at the computer screen for a long time. In the past, symptoms such as dry eyes and blurred vision would appear after working for 2-3 hours, but now they can continue to work for more than 4-5 hours, and their visual comfort has been significantly improved. This is because the peripheral diffusion area of ​​the lens achieves optimized adjustment of the contrast at different positions according to the visual needs of its peripheral retina. For example, the contrast is appropriately reduced in areas of the peripheral retina that are prone to visual fatigue, reducing excessive stimulation of visual information; at the same time, the contrast is maintained or appropriately enhanced in areas where visual attention is focused, improving the perception of details such as graphics and text on the computer screen, thereby improving work efficiency.

[0048] Comprehensive visual function evaluation: After 3 months of wearing experience, the adult was given a comprehensive visual function evaluation, including contrast sensitivity test, stereoscopic vision test, visual reaction time test, etc. The contrast sensitivity test results showed that the contrast sensitivity in the medium and high frequency bands was significantly improved, indicating that the lens improved its ability to distinguish objects of different contrasts; the stereoscopic vision test results were normal, indicating that the lens did not have an adverse effect on stereoscopic vision; in the visual reaction time test, the reaction time was shortened by about 10%, which means that the lens helps to improve the speed of visual information processing and makes the wearer more agile in visual tasks.

[0049] Clinical research support

[0050] Research design and methods: A 36-month multicenter, randomized, controlled, double-blind trial (CYPRESS, NCT03623074) conducted an in-depth study on the effectiveness and safety of the lenses of the present invention. A total of 256 myopic children aged 6-10 years were included in the study and randomly divided into test group 1, test group 2 and control group, wearing different eyeglass lenses. The main observation indicators were the changes in axial length (AL) and spherical equivalent refraction (SER) relative to baseline.

[0051] Results and data analysis: In all groups, the mean baseline AL was 24.02 mm (SD ± 0.77 mm), the SER was -2.01 D (SD ± 0.9 D) using manifest refraction, and -1.94 D (SD ± 1.0 D) using ciliary muscle paralysis autorefraction. At 12 months, the mean difference in SER progression between Test 1 and control was -0.40 D (p < 0.0001), representing a 74% reduction, and -0.32 D (p < 0.0001), representing a 59% reduction, for Test 2. The difference in AL axial progression between Test 1 and control was 0.15 mm (p < 0.0001), and the difference in AL progression between Test 2 and control was 0.10 mm (p = 0.0018). The average Test 1 lens reduced myopia progression by an average of 0.56 D over 12 months. These data indicate that the DOT spectacle lenses of the present invention are significantly effective in slowing down the progression of myopia in children, and have good safety and a low incidence of adverse events.

[0052] The above embodiments and clinical studies show that the DOT peripheral diffusion retinal contrast adjustment lens of the present invention can directly refract and illuminate the fovea of ​​the retina through a unique structural design when the visual light passes through the central optical zone, forming a clear visual image. The light in the peripheral optical zone is diffused through the fovea, and only a faint light enters the outside of the retinal macular area. Compared with the light passing through the central optical zone, the contrast is increased. The present invention provides an innovative, efficient, safe and broadly applicable method for myopia prevention and control and visual function optimization.

[0053] The above specific embodiments further illustrate the purpose, technical solutions and beneficial effects of the present invention. It should be understood that the above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical solutions and inventive concepts of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

[0054] In addition, in the description of the present invention, it should be understood that the terms indicating orientation or positional relationships are based on the orientation or positional relationships shown in the drawings and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0055] Furthermore, in the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. A DOT peripheral diffuse retinal contrast adjustment lens, characterized in that: It includes a central optical zone for correcting refractive errors of central vision and a peripheral diffusion zone that surrounds the central optical zone and adjusts the peripheral retinal contrast through optical microstructures.

2. A DOT peripheral diffuse retinal contrast adjustment lens according to claim 1, characterized in that: The central optical area can be individually customized according to the wearer's myopia, hyperopia or astigmatism to ensure clear correction of central vision.

3. The DOT peripheral diffuse retinal contrast adjustment lens according to claim 1, characterized in that: The optical microstructure of the peripheral diffusion area includes a microlens having a specific curvature radius range, and adjusts the light distribution and contrast of the peripheral retina by refraction of light.

4. The DOT peripheral diffuse retinal contrast adjustment lens according to claim 1, characterized in that: The optical microstructure of the peripheral diffusion area is a plurality of micro-cavities arranged on the mirror surface and used for reflecting and filtering light beams.

5. The DOT peripheral diffuse retinal contrast adjustment lens according to claim 1, characterized in that: The peripheral diffusion area can achieve differentiated adjustment of light contrast at different positions according to the visual needs of different areas of the peripheral retina, including local contrast enhancement and local contrast reduction functions.

6. The DOT peripheral diffuse retinal contrast adjustment lens according to claim 1, characterized in that: The central optical area and the peripheral diffusion area cooperate with each other in optical performance. The central optical area ensures clear imaging of central vision, and the peripheral diffusion area optimizes the peripheral retinal visual function, jointly improving the overall visual quality of the wearer.

7. A method for manufacturing the DOT peripheral diffuse retinal contrast adjustment lens according to any one of claims 1 to 8, comprising: Based on the refractive data of the wearer's central vision, conventional lens processing technology is used to manufacture basic lenses that meet the standards in the central optical area.

8. The method for manufacturing a DOT peripheral diffuse retinal contrast adjustment lens according to claim 9, characterized in that: It also includes the use of micromachining technology to construct an optical microstructure of the peripheral diffusion area around the base lens, strictly controlling the various parameters of the microstructure, and then using special coating or surface treatment processes to generate a transition area to ensure the consistency and stability of the overall optical performance of the lens and to meet the design requirements of peripheral retinal contrast adjustment. The micromachining technology includes but is not limited to photolithography and electron beam etching technology.

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