A Chinese medicinal compound for improving pigeon immunity and pigeon egg quality

By using a specific proportion of traditional Chinese medicine compound, the existing antibiotics and chemical synthetic drugs are solved for the increase of drug-resistant strains and drug residues during pigeon diarrhea, and the effect of improving pigeon immunity, improving pigeon egg quality and rapid treatment of non-communicable diarrhea is achieved.

CN119770604AActive Publication Date: 2025-04-08RUIAN RICH PIGEON IND CO LTD
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Patent Information

Application Number
CN202510284589.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-11
Publication Date
2025-04-08
Estimated Expiration
2045-03-11

AI Technical Summary

Technical Problem

Most of the existing drugs used to prevent and treat pigeon diarrhea are antibiotics and chemical synthetic drugs, which lead to problems such as the increase of drug-resistant strains and drug residues, which seriously restricts the healthy development of the pigeon breeding industry.

Method used

Provide a compound Chinese medicine prescription, including Northern Bupleurum, Pueraria root, licorice, dandelion, Astragalus, Scutellaria baicalensis, Qianghuo, Angelica dahurica, White Peony, Platycodon, Gypsum, Legumin, Coix seed, Sophora glutinosa, Coix seed, Sophora glutinosa, Coix seed, Scutellaria coptis, Polygonum sinensis, Forsythia sinensis, Forsythia, Jupitera, Curcuma zedo, Honeysuckle, Big Green Leaf, Yuan Ginseng, Summer Dead Flower, fried chicken gizzard, Huai Yam, Prince Ginseng, Yinchen, Snake Honeysuckle, etc., through specific compatibility ratios and preparation processes, effective medicines are formed.

Benefits of technology

Significantly improve pigeon immunity, improve pigeon egg quality, quickly and effectively treat non-communicable diarrhea, reduce pigeon mortality without causing drug resistance and drug residues.

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Abstract

The present invention is a Chinese medicine compound with northern bupleurum, kudzu, liquorice, dandelion, astragalus, scutellaria, notopterygium, angelica, white peony root, platycodon, gypsum, kochia fruit, coix seed, sophora flavescens, coptis root, poria, polygonatum, forsythia, gallnut, curcuma, honeysuckle, isatis indigotica, yuanshen, prunella vulgaris, stir-fried chicken gizzard lining, Chinese yam, pseudostellaria, capillaris, and hops as main ingredients, which is processed to prepare Chinese medicine powder, and mixed with basic feed to feed pigeons. The Chinese medicine compound can not only be used as a health care drug to improve the immunity of pigeons, increase the weight of pigeons, and improve the quality of pigeon eggs, but also can assist in treating pigeon diarrhea, can be used as a two-pronged high-efficiency therapeutic drug, and has high economic value and practicality.
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Description

Technical Field

[0001] The invention belongs to the field of medical technology, and specifically relates to a traditional Chinese medicine compound for improving pigeon immunity and pigeon egg quality and a preparation process thereof, as well as application of the traditional Chinese medicine compound in treating non-infectious diarrhea. Background Art

[0002] After more than 40 years of development and accumulation, my country's pigeon farming industry has entered a new round of rapid development, thanks to the rapid demand for high-quality poultry meat and eggs. Pigeon farming has become a pillar industry in my country's breeding industry. However, with large-scale breeding, the conditions of pigeon houses and the nutritional value of feed directly affect the immunity of pigeons. For example, poor ventilation in pigeon houses, simple feed, and frequent diarrhea, bacterial or trichomonal infections can easily cause pigeons to grow slowly, egg production decreases, and the quality of pigeon eggs decreases. At present, the drugs used to prevent and treat pigeon diarrhea are mostly antibiotics, chemical synthetic drugs, etc. Although these drugs can play a certain therapeutic effect and achieve a certain prevention and treatment effect, they also bring a series of difficult-to-solve problems such as the increase of drug-resistant strains and drug residues, which seriously restrict the healthy development of the pigeon industry. Summary of the invention

[0003] The invention provides a traditional Chinese medicine compound for improving pigeon immunity and improving pigeon egg quality. The traditional Chinese medicine compound is composed of the following raw materials in parts by weight: 10-12 parts of northern bupleurum, 10-12 parts of pueraria root, 18-20 parts of liquorice, 18-20 parts of dandelion, 18-20 parts of astragalus, 10-12 parts of scutellaria, 10-12 parts of notopterygium, 10-12 parts of angelica dahurica, 10-12 parts of white peony root, 10-12 parts of platycodon, 15-18 parts of gypsum, 10-12 parts of kochia scoparia, and coix lachryma-jobi. 18-20 parts of kernel, 15-18 parts of sophora flavescens, 10-12 parts of coptis root, 15-18 parts of poria, 10-12 parts of polygonatum, 10-12 parts of forsythia, 10-12 parts of gallnut, 15-18 parts of curcuma, 10-12 parts of honeysuckle, 18-20 parts of isatis indigotica, 15-18 parts of yuanshen, 15-18 parts of prunella vulgaris, 15-18 parts of stir-fried chicken gizzard lining, 15-18 parts of yam, 15-18 parts of pseudostellaria, 10-12 parts of capillaris, and 10-12 parts of hops.

[0004] Preferably, the Chinese medicine compound is composed of the following raw materials in parts by weight: 12 parts of northern bupleurum, 10 parts of pueraria root, 20 parts of licorice, 20 parts of dandelion, 20 parts of astragalus, 12 parts of scutellaria, 10 parts of notopterygium, 10 parts of angelica dahurica, 12 parts of white peony root, 10 parts of platycodon, 15 parts of gypsum, 10 parts of kochia fruit, 20 parts of coix seed, 15 parts of sophora flavescens, 10 parts of coptis root, 15 parts of poria, 10 parts of polygonatum, 12 parts of forsythia, 10 parts of gallnut, 15 parts of curcuma, 12 parts of honeysuckle, 20 parts of isatis indigotica, 15 parts of yuanshen, 15 parts of selfhealing flower, 15 parts of stir-fried chicken gizzard lining, 15 parts of yam, 15 parts of pseudostellaria, 12 parts of capillaris, and 10 parts of hemp seeds.

[0005] The active ingredients of the drug efficacy provided by the present invention are as follows: Northern Bupleurum: It has the effects of reconciling the exterior and interior, soothing the liver and raising yang.

[0006] Pueraria root: has the effect of relieving muscles and reducing fever.

[0007] Licorice: It has the effects of invigorating Qi and tonifying the middle, clearing away heat and detoxifying, removing phlegm and relieving cough. When used together with other medicines, it also has the effects of moisturizing and lubricating the intestines. The effective ingredient for treating diarrhea is licorice flavonoids.

[0008] Dandelion: Dandelion contains ingredients such as taraxacin and taraxasterol, which have antibacterial, anti-inflammatory and diuretic effects.

[0009] Astragalus: Astragalus contains astragalus polysaccharides, astragaloside and other ingredients, which have the effects of enhancing immunity and antibacterial.

[0010] Scutellaria baicalensis: It has the effects of clearing away heat and dampness, purging fire and detoxifying.

[0011] Qianghuo: It has the effects of dispelling cold, expelling wind and removing dampness.

[0012] Angelica dahurica: It has the effects of dispelling cold, reducing swelling and discharging pus.

[0013] White Peony Root: It has the effects of nourishing blood and regulating menstruation, astringing yin and stopping sweating, softening the liver and relieving pain, and calming liver yang.

[0014] Platycodon: Platycodon contains platycodon saponins, platycodic acid and other ingredients, which have anti-inflammatory, expectorant, and immunity-enhancing effects.

[0015] Gypsum: Gypsum contains ingredients such as calcium sulfate, which has the effects of clearing heat and detoxifying, and stopping diarrhea.

[0016] Kochia seeds: Kochia seeds contain volatile oils, flavonoids and other ingredients, which have anti-inflammatory, antibacterial and diuretic effects.

[0017] Job's tears: Job's tears contain ingredients such as coixol and coix polysaccharide, which have the effects of enhancing immunity, anti-inflammatory, and anti-cancer.

[0018] Sophora flavescens: Sophora flavescens contains ingredients such as matrine and oxymatrine, which have anti-inflammatory, antibacterial and antiviral effects.

[0019] Coptis chinensis: Coptis chinensis contains ingredients such as berberine and berberine, which have antibacterial, anti-inflammatory, and immunity-enhancing effects.

[0020] Poria: Poria contains pachymannan, pachymannic acid and other ingredients, which have the effects of enhancing immunity and anti-inflammatory.

[0021] Polygonatum: Polygonatum contains polygonatum polysaccharides, steroidal saponins and other ingredients, which have the effects of enhancing immunity and anti-oxidation.

[0022] Forsythia: Forsythia contains ingredients such as forsythiaside and forsythia glycoside, which have antibacterial, anti-inflammatory and antiviral effects.

[0023] Gallnut: Gallnut contains ingredients such as galltannin, which has antibacterial and antidiarrheal effects.

[0024] Curcuma: Curcuma contains volatile oil, curcumin and other ingredients, which have anti-inflammatory, antibacterial and anti-cancer effects.

[0025] Honeysuckle: Honeysuckle contains ingredients such as chlorogenic acid and luteolin, which have antibacterial, anti-inflammatory and antiviral effects.

[0026] Folium Isatidis: Folium Isatidis contains ingredients such as indigo carmine and indigo, which have antibacterial, antiviral and anti-inflammatory effects.

[0027] Radix Ginseng: Radix Ginseng contains saponins, alkaloids and other ingredients, which have antibacterial, anti-inflammatory and immunity-enhancing effects.

[0028] Prunella Vulgaris: Prunella Vulgaris contains flavonoids, volatile oils and other ingredients, which have antibacterial and anti-inflammatory effects.

[0029] Fried chicken gizzard lining: Fried chicken gizzard lining contains gastric hormone, keratin and other ingredients, which have the effects of promoting digestion and enhancing appetite.

[0030] Huai yam: Huai yam contains ingredients such as yam alkaloids and mucin, which have the effects of enhancing immunity and resisting fatigue.

[0031] Radix Pseudostellariae: Radix Pseudostellariae contains Pseudostellariae polysaccharides, steroidal saponins and other ingredients, which have the effect of enhancing immunity.

[0032] Artemisia capillaris: Artemisia capillaris contains ingredients such as artemisinin and volatile oil, which have antibacterial and anti-inflammatory effects.

[0033] Hops: Hops contain volatile oils, alkaloids and other ingredients, which have anti-inflammatory and immunity-enhancing effects.

[0034] In the field of traditional Chinese medicine, the compatibility of drugs is an important means to improve the efficacy and reduce toxic and side effects. After extensive research, the inventor of the present application found that the Chinese medicine compound is mixed with 12 parts of Bupleurum chinense, 10 parts of Pueraria lobata, 20 parts of Licorice, 20 parts of Taraxacum officinale, 20 parts of Astragalus, 12 parts of Scutellaria baicalensis, 10 parts of Notopterygium wilfordii, 10 parts of Angelica dahurica, 12 parts of White Peony Root, 10 parts of Platycodon grandiflorum, 15 parts of Gypsum, 10 parts of Kochia scoparia, 20 parts of Coix seeds, 15 parts of Sophora flavescens, 10 parts of Coptis chinensis, 15 parts of Poria, 10 parts of Polygonatum sibiricum, 12 parts of Forsythia suspensa, 10 parts of Galla chinensis, 15 parts of Curcuma zedoaria, 12 parts of Honeysuckle, 20 parts of Isatis indigotica, 15 parts of Radix Rehmanniae, 15 parts of Prunella Vulgaris, 15 parts of Fried Chicken Gizzard Stone, 15 parts of Chinese Yam, 15 parts of Pseudostellariae Pseudostellariae, 12 parts of Capillaris, and 10 parts of Humulus Humulus. Under the condition that the total dosage of the compound is the same, a slight change in the dosage of each drug has little effect on the experimental results. Therefore, the Chinese medicine compound of the present invention is composed of the following ingredients in parts by weight: 10-12 parts of Bupleurum chinense, 10-12 parts of Pueraria lobata, 18-20 parts of Licorice, 18-20 parts of Taraxacum mongolicum, 18-20 parts of Astragalus membranaceus, 10-12 parts of Scutellaria baicalensis, 10-12 parts of Notopterygium wilfordii, 10-12 parts of Angelica dahurica, 10-12 parts of White Peony Root, 10-12 parts of Platycodon grandiflorum, 15-18 parts of Gypsum, 10-12 parts of Kochia scoparia , 18-20 parts of coix seed, 15-18 parts of sophora flavescens, 10-12 parts of coptis chinensis, 15-18 parts of poria, 10-12 parts of polygonatum, 10-12 parts of forsythia, 10-12 parts of gallnut, 15-18 parts of curcuma, 10-12 parts of honeysuckle, 18-20 parts of isatis indigotica, 15-18 parts of yuanshen, 15-18 parts of selfhealing flower, 15-18 parts of stir-fried chicken gizzard lining, 15-18 parts of yam, 15-18 parts of pseudoginseng, 10-12 parts of capillaris, and 10-12 parts of hops.

[0035] More importantly, after many experimental studies, it was found that in this Chinese medicine prescription, the mutual compatibility between licorice, dandelion, astragalus, poria, gypsum, coptis, and platycodon is crucial. The weight ratio of licorice, dandelion, astragalus, poria, gypsum, coptis, and platycodon is 4:4:4:3:3:2:2, which can maximize the cost-effectiveness of the medicine. If the dosage of coptis and platycodon is too much, it is easy to cause indigestion, affecting the pigeons' feed intake and weight loss. Licorice, dandelion, and astragalus are one of the main medicinal ingredients. The high ratio can effectively improve non-infectious diarrhea in caged pigeons and greatly shorten the recovery time.

[0036] In addition, after dosage screening, it was found that preferably, the weight ratio of the Chinese medicine compound to the basic feed is 0.5g / kg-1g / kg, which can maximize the cost-effectiveness of the medicine. More preferably, the weight ratio of the Chinese medicine compound to the basic feed is 0.5g / kg.

[0037] On the other hand, the present invention also provides a preparation process of the Chinese medicine compound, comprising the following steps: S1: Weigh gypsum and gallnut, crush them into powder, and obtain a crushed material; S2: Weigh the remaining medicinal materials, add 3-5 times the amount of water, soak for 1-3 hours, boil for 3-5 hours, filter, concentrate, and obtain an extract; S3: The crushed product obtained in step S1 and the extract obtained in step S2 are mixed, and low-temperature dried at 30-40° C. to obtain a powder.

[0038] In some embodiments, in step S1, the particle size of the powder is 40 mesh.

[0039] In some embodiments, in step S2, 3 times the amount of water is added and soaked for 1.5 hours.

[0040] In some embodiments, in step S2, the cooking time is 3 hours.

[0041] On the other hand, the Chinese medicinal compound of the present invention is used in the preparation of a medicine for treating and improving the immunity of pigeons and the quality of pigeon eggs.

[0042] On the other hand, the Chinese medicinal compound of the present invention is used in preparing a medicine for treating non-infectious diarrhea in pigeons.

[0043] Beneficial effects: In combination with the above technical solutions and the technical problems to be solved, the beneficial effects of the technical solutions to be protected by the present invention are analyzed from the following aspects: 1. Improve pigeon immunity: The Chinese medicine compound provided by the present invention is mainly composed of Bupleurum chinense, Pueraria lobata, Licorice, Taraxacum mongolicum, Astragalus, Scutellaria baicalensis, Notopterygium wilfordii, Angelica dahurica, White Peony Root, Platycodon grandiflorum, Gypsum, Kochia scoparia, Coix seeds, Sophora flavescens, Coptis chinensis, Poria, Polygonatum sibiricum, Forsythia suspensa, Gallnut, Curcuma zedoaria, Honeysuckle, Folium Isatidis, Radix Rehmanniae, Prunella vulgaris, Stir-fried Chicken Gizzard, Chinese Yam, Radix Pseudostellariae, Capillaris, and Semen Coptis chinensis. After processing, it is prepared into Chinese medicine powder. After clinical and efficacy tests, it is found that the Chinese medicine compound can significantly improve the immunity of pigeons and reduce the mortality rate of pigeons. By adding 0.5g / kg-1g / kg of the Chinese medicine compound to the basic feed, the weight of the pigeon increases significantly and the mortality rate is significantly reduced.

[0044] 2. Improve the quality of pigeon eggs: The Chinese medicine compound of the present invention can significantly improve the quality of pigeon eggs, increase the eggshell strength, and reduce the breakage rate of pigeon eggs during transportation and storage. Experimental data show that after using the Chinese medicine compound of the present invention, the eggshell strength of pigeon eggs is significantly improved compared with the blank control group, and the egg weight is also increased, which is more conducive to improving the market competitiveness of pigeon eggs.

[0045] 3. Treatment of non-infectious diarrhea: In the treatment of diarrheal diseases in pigeons, the cause of non-infectious diarrhea in caged pigeons is complex and cannot be accurately found. Unlike bacterial or viral infections, antibiotics and other therapeutic drugs have no therapeutic effect on the disease, or even if antibiotics are used for treatment, it is easy to cause a series of difficult-to-solve problems such as an increase in drug-resistant strains and drug residues. The Chinese medicine compound of the present invention can treat non-infectious diarrhea in caged pigeons, has a quick effect, and has a good efficacy, solving the technical gap of the lack of accurate treatment methods and effective drugs for the disease.

[0046] In summary, the Chinese medicine compound provided by the present invention can not only be used as a health-care drug to improve the immunity of pigeons, promote the weight gain of pigeons, and improve the quality of pigeon eggs, but also can assist in the treatment of non-infectious diarrhea in pigeons. It can be used as a two-pronged and efficient therapeutic drug, and has high economic value and practicality. DETAILED DESCRIPTION

[0047] The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0048] Unless otherwise specified, the reagents or consumables used in the present invention are commercially available.

[0049] Example 1 Chinese medicine compound: 12 parts of Bupleurum chinense, 10 parts of Pueraria lobata, 20 parts of Licorice, 20 parts of Taraxacum, 20 parts of Astragalus, 12 parts of Scutellaria, 10 parts of Notopterygium wilfordii, 10 parts of Angelica dahurica, 12 parts of White Peony Root, 10 parts of Platycodon grandiflorum, 15 parts of Gypsum, 10 parts of Kochia scoparia, 20 parts of Coix seeds, 15 parts of Sophora flavescens, 10 parts of Coptis chinensis, 15 parts of Poria, 10 parts of Polygonatum sibiricum, 12 parts of Forsythia suspensa, 10 parts of Galla chinensis, 15 parts of Curcuma zedoaria, 12 parts of Honeysuckle, 20 parts of Isatis indigotica, 15 parts of Radix Glehniae, 15 parts of Prunella Vulgaris, 15 parts of Stir-fried Chicken Gizzard Stone, 15 parts of Chinese Yam, 15 parts of Pseudostellaria pseudoginseng, 12 parts of Capillaris, 10 parts of Humulus lucidus; Preparation process: S1) pulverizing: weigh the above-mentioned gypsum and gallnut in parts by weight, pulverize them into powder, and pass them through a 40-mesh sieve to obtain a pulverized product; S2) Extraction treatment: weigh the remaining medicinal materials, add 3 times the amount of water, soak for 1.5 hours, boil for 3-5 hours, filter, concentrate, and obtain an extract; S3) The pulverized product obtained in step S1) and the extract obtained in step S2) are mixed and low-temperature dried at 30° C. to obtain a powder.

[0050] Comparative Example 1 Chinese medicine compound: 12 parts of Bupleurum chinense, 20 parts of Astragalus membranaceus, 15 parts of Poria cocos, and 20 parts of Licorice.

[0051] Preparation process: Weigh the above-mentioned medicinal materials in parts by weight, add 3 times the amount of water, soak for 1.5 hours, boil for 3-5 hours, filter, concentrate to obtain an extract; and dry at 30° C. to obtain a powder.

[0052] Comparative Example 2 Chinese medicine compound: 12 parts of Bupleurum chinense, 20 parts of Astragalus membranaceus, 15 parts of Poria cocos, 20 parts of Licorice, 12 parts of Scutellaria baicalensis, 15 parts of Prunella vulgaris, 12 parts of Forsythia suspensa, 10 parts of Gallnut, 15 parts of Pseudostellaria pseudoginseng, and 12 parts of Capillaries.

[0053] Preparation process: Weigh the above-mentioned medicinal materials in parts by weight, add 3 times the amount of water, soak for 1.5 hours, boil for 3-5 hours, filter, concentrate to obtain an extract; and dry at 30° C. to obtain a powder.

[0054] Comparative Example 3 Chinese medicine compound: 12 parts of bupleurum, 10 parts of pueraria root, 20 parts of liquorice, 20 parts of dandelion, 20 parts of astragalus, 12 parts of scutellaria, 10 parts of notopterygium, 10 parts of angelica, 12 parts of white peony root, 10 parts of platycodon, 15 parts of gypsum, 10 parts of kochia fruit, 20 parts of coix seed, 15 parts of sophora flavescens, 10 parts of coptis root, 15 parts of poria, 10 parts of polygonatum, 12 parts of forsythia, 10 parts of gallnut, 15 parts of curcuma, 12 parts of honeysuckle, 20 parts of isatis indigotica, 15 parts of yuanshen, 15 parts of prunella vulgaris, 15 parts of stir-fried chicken gizzard lining, 15 parts of yam, 15 parts of pseudostellaria, 12 parts of capillaris, 10 parts of hemp seeds; Preparation process: The above Chinese medicinal ingredients were weighed, crushed, mixed evenly, and passed through a 40-mesh sieve to obtain powder.

[0055] Experimental Example 1 Experimental animals and experimental methods 1.1 Experimental subjects: 500 healthy adult pigeons of equivalent weight were selected from this pigeon farm.

[0056] 1.2 Experimental method: Divided into 5 experimental groups on average, blank control group, embodiment group, control group 1, control group 2, control group 3, 100 in each group. Each group first had a pre-feeding period of 7 days, during which the basic feed was uniformly fed, and the basic feed (blank control group) was fed daily from the beginning of the formal period, and the amount of the Chinese medicine compound powder obtained in Example 1 added to the feed was 0.5 g / kg (Chinese medicine compound / feed) as the embodiment group, comparative example 1, comparative example 2, comparative example 3, and the amount of the Chinese medicine compound powder added to the feed was 0.5 g / kg (Chinese medicine compound / feed) as the control group 1, control group 2, and control group 3, respectively, for 7 consecutive days, followed by feeding the basic feed for 14 days, a total of 21 days, and repeated three cycles for a total of 63 days.

[0057] 1.3 Performance measurement method 1.3.1 Pigeon egg quality indicators The egg weight and eggshell strength of each group were recorded and processed according to the recorded data. The determination method is as follows, and the determination results are shown in Table 1.

[0058] Egg weight: Weigh with an electronic balance to an accuracy of 0.1 g and calculate the average value.

[0059] Eggshell strength: Eggshell strength is the pressure per unit area of ​​the eggshell (N / cm 2 ), the stronger the eggshell is, the better it can resist the impact during circulation and reduce the breakage rate. It can be measured using an eggshell strength tester.

[0060] Table 1 Test results of pigeon egg performance Group Egg weight (g) Eggshell strength (N / cm2) Blank control group 18.1±0.1 3.35±0.15 Example Group 18.5±0.1 3.65±0.16 Control group 1 18.2±0.2 3.45±0.12 Control group 2 18.2±0.1 3.55±0.14 Control group 3 18.4±0.3 3.61±0.19 1.3.2 Growth and development of pigeons The weight gain and mortality of the pigeons were observed throughout the whole period. The results are shown in Table 2.

[0061] Table 2 Weight changes and mortality of pigeons Group Pigeon weight gain (g) Number of dead pigeons mortality rate(%) Blank control group 39.32±2.54 7 7 Example Group 57.32±4.22 2 2 Control group 1 53.23±4.98 3 3 Control group 2 54.31±5.54 4 4 Control group 3 51.33±3.76 2 2 As shown in Table 1, compared with the blank control group, the weight of pigeon eggs in the embodiment group increased, especially the eggshell strength was significantly higher than that in the blank control group (P < 0.05). Compared with the control groups 1-3, the weight of pigeon eggs and the eggshell strength were significantly improved. As shown in Table 2, the Chinese medicine compound described in the embodiment of the present invention is beneficial to the growth of pigeons, especially for the embodiment group, it does not affect the feed intake of pigeons, the weight of pigeons increases significantly, and the mortality rate is low.

[0062] Experimental Example 2: Optimal Dose Selection of Traditional Chinese Medicine Compound Granules According to 0.2g, 0.5g, 1.0g, 2.0g / kg Chinese medicine compound / feed, pigeons are fed, wherein, using 0.5g / kg, 1.0g / kg dosage can make the egg weight of pigeon eggs moderate, and can maintain the good strength of eggshell, reduce the breakage rate of pigeon eggs. Wherein, increase the Chinese medicine content to 2.0g / kg Chinese medicine compound / feed, the Chinese medicine ratio increases, affects the feed intake, and the pigeon weight increases slowly. Use lower Chinese medicine content, such as 0.2g / kg Chinese medicine compound / feed to improve pigeon egg quality less. Therefore, combined with the impact on pigeon egg quality, pigeon growth and development, and economic cost, the present invention selects 0.5-1g / kg as the optimal dosage, and the results are shown in Table 3.

[0063] Table 3 Screening results of optimal dose of Chinese medicine compound granules Dosage (g / kg (TCM compound / feed) Egg weight (g) Eggshell strength (N / cm2) Feed intake (g / bird / day) 0.2 18.2±0.1 3.52±0.15 45 0.5 18.5±0.1 3.62±0.16 45 1.0 18.5±0.2 3.60±0.12 45 2.0 18.5±0.1 3.60±0.14 40 In summary, it can be seen from Tables 1 to 3 that the Chinese herbal compound of the present invention is beneficial to improving the immunity of pigeons. Regularly feeding the Chinese herbal compound of the present invention in daily breeding can effectively increase the weight of pigeons and reduce the mortality rate of pigeons.

[0064] In terms of the quality of pigeon eggs, the Chinese medicinal compound of the present invention can significantly improve the eggshell strength, thereby improving the quality of pigeon eggs and reducing the breakage of pigeon eggs during production and transportation.

[0065] Experimental Example 3 3.1. Effects of not taking treatment measures on pigeons with non-infectious diarrhea The pigeons with diarrhea in the pigeon farm of Rui'an City, Zhejiang Province were observed. The changes in the condition of the pigeons were observed on the 1st, 3rd, 5th, 7th and 9th days. It was found that if the diarrhea was not treated in time, the pigeons would eat less, lose weight and die. The results are shown in Table 4.

[0066] Table 4. The changes in the condition of pigeons suffering from non-infectious diarrhea after 9 days Days Medication (g / kg (Chinese medicine compound / feed) Number of sick pigeons Feed intake (g / bird / day) Total number of pigeon deaths mortality rate(%) 1 day 0 40 45 0 0 3 days 0 40 44 1 2.5 5 days 0 40 43 5 12.5 7 days 0 40 40 7 17.5 9 days 0 40 38 10 25.0 3.2. Efficacy of Chinese herbal compound preparations on non-infectious diarrhea in pigeons Medication method: 40 pigeons with non-infectious diarrhea in the pigeon farm were selected, and they were fed with 0.5g / kg (Chinese herbal compound / feed) for 3 days. The changes in the pigeons' condition were observed on the 1st, 3rd, 5th, 7th and 9th days. The results are shown in Table 5.

[0067] Table 5 The therapeutic effect of Chinese herbal compound Days Medication g / kg (Chinese medicine compound / feed) Number of sick pigeons Feed intake (g / bird / day) Total number of pigeon deaths mortality rate(%) 1 day 0.5 40 45 0 0 3 days 0.5 40 44 2 5.0 5 days 0.5 40 46 2 5.0 7 days 0.5 40 45 3 7.5 9 days 0.5 40 46 3 7.5 As can be seen from the above table, the use of the Chinese herbal compound described in this embodiment to treat pigeons suffering from non-infectious diarrhea significantly reduced the number of pigeon deaths, with a mortality rate of only 7.5%. On the 5th day, the pigeons began to recover their feed intake and their weight returned to normal.

[0068] 3.3 Comparison of the efficacy of Chinese herbal compound preparations and other treatments Non-infectious pigeon diarrhea is often caused by the pigeon house environment, improper diet structure, gastrointestinal flora imbalance, etc. It is different from bacterial or viral infection. Antibiotics and other therapeutic drugs have no therapeutic effect on the disease, or even if antibiotics are used for treatment, they are prone to increase in drug-resistant strains and drug residues, etc. A series of difficult-to-solve problems. However, measures to improve the pigeon house environment or adjust the diet structure are slow to take effect and the pigeon mortality rate is high. 90 pigeons with non-infectious diarrhea in the pigeon house were treated and randomly divided into 3 groups, each with 30 pigeons. They were treated for 7 days by improving the pigeon house, adjusting the diet, and using a Chinese medicine compound (0.5g / kg (Chinese medicine compound / feed in Example 1)). After 30 days of observation, the mortality rate, recovery time, and weight changes of pigeons in different treatment methods were statistically analyzed. The comparison of treatment effects is shown in Table 6.

[0069] Table 6 Comparison of the efficacy of Chinese herbal compound granules and other treatments Treatment Time required for recovery (days) mortality rate(%) Pigeon weight gain (g) Improving the pigeon loft environment 15 30.0 -10.34±2.11 Adjust your diet 13 26.6 -3.32±3.89 Medication: 0.5g / kg (Chinese medicine compound / feed) 5 10.0 6.89±5.21 It can be seen from Tables 4-6 above that for pigeons suffering from non-infectious diarrhea, the Chinese medicine compound described in this embodiment effectively improves the diarrhea symptoms of the pigeons, greatly shortens the recovery time, and at the same time improves the pigeons' feed intake, maintains their body weight unchanged, and reduces the mortality rate of the pigeons.

[0070] In summary, the performance of the Chinese medicine compound of the present invention in terms of pigeon egg quality is better than that of the blank control group. And the Chinese medicine compound does not add antibiotics, will not cause drug resistance, and will not bring hidden dangers to food safety, providing new ideas for a non-antibiotic, green and healthy breeding model. In addition, the Chinese medicine compound also has the functions of promoting nutrient absorption, quickly restoring damaged functions of the body, improving the immunity of pigeons, significantly improving diarrhea symptoms of non-infectious diarrhea, greatly shortening the recovery time, and improving the feed intake of pigeons, keeping their weight unchanged, and reducing the mortality rate of pigeons.

[0071] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and substitutions can be made without departing from the technical principles of the present invention. These improvements and substitutions should also be regarded as the scope of protection of the present invention.

Claims

1. A Chinese medicinal compound for improving pigeon immunity and pigeon egg quality, characterized in that: The Chinese medicine compound is composed of the following raw materials in parts by weight: 10-12 parts of northern bupleurum, 10-12 parts of pueraria root, 18-20 parts of liquorice, 18-20 parts of dandelion, 18-20 parts of astragalus, 10-12 parts of scutellaria, 10-12 parts of notopterygium, 10-12 parts of angelica dahurica, 10-12 parts of white peony root, 10-12 parts of platycodon, 15-18 parts of gypsum, 10-12 parts of kochia scoparia, 18-20 parts of coix seed, 15-18 parts of sophora flavescens, 8 parts, 10-12 parts of Coptidis Rhizoma, 15-18 parts of Poria, 10-12 parts of Polygonatum, 10-12 parts of Fructus Forsythiae, 10-12 parts of Gallnut, 15-18 parts of Curcuma, 10-12 parts of Flos Lonicerae, 18-20 parts of Folium Isatidis, 15-18 parts of Radix Yuanshen, 15-18 parts of Prunella Vulgaris, 15-18 parts of stir-fried Chicken Gizzard Stone, 15-18 parts of Chinese Yam, 15-18 parts of Radix Pseudostellariae, 10-12 parts of Capillaris, and 10-12 parts of Semen Humuli.

2. The Chinese medicinal compound according to claim 1, characterized in that: The Chinese medicine compound is composed of the following raw materials in parts by weight: 12 parts of northern bupleurum, 10 parts of pueraria root, 20 parts of liquorice, 20 parts of dandelion, 20 parts of astragalus, 12 parts of scutellaria, 10 parts of notopterygium, 10 parts of angelica dahurica, 12 parts of white peony root, 10 parts of platycodon, 15 parts of gypsum, 10 parts of kochia fruit, 20 parts of coix seed, 15 parts of sophora flavescens, 10 parts of coptis root, 15 parts of poria, 10 parts of polygonatum, 12 parts of forsythia, 10 parts of gallnut, 15 parts of curcuma, 12 parts of honeysuckle, 20 parts of isatis indigotica, 15 parts of yuanshen, 15 parts of prunella vulgaris, 15 parts of stir-fried chicken gizzard lining, 15 parts of yam, 15 parts of pseudostellaria, 12 parts of capillaris, and 10 parts of hemp seeds.

3. The Chinese medicinal composition according to claim 1, characterized in that: The preparation process of the Chinese medicine compound comprises the following steps: S1: Weigh gypsum and gallnut, crush them into powder, and obtain a crushed material; S2: Weigh the remaining medicinal materials, add 3-5 times the amount of water, soak for 1-3 hours, boil for 3-5 hours, filter, concentrate, and obtain an extract; S3: The crushed product obtained in step S1 and the extract obtained in step S2 are mixed, and low-temperature dried at 30-40° C. to obtain a powder.

4. The Chinese medicinal compound according to claim 3, characterized in that: In the step S1, the particle size of the powder is 40 mesh.

5. The Chinese medicinal compound according to claim 3, characterized in that: In step S2, 3 times the amount of water is added and soaked for 1.5 hours.

6. The Chinese medicinal compound according to claim 3, characterized in that: In step S2, the cooking time is 3 hours.

7. Use of the Chinese medicinal compound as described in any one of claims 1-6 in preparing a medicine for treating and improving pigeon immunity and pigeon egg quality.

8. Use of the Chinese medicinal compound according to any one of claims 1 to 6 in preparing a medicament for treating non-infectious diarrhea in pigeons.

Citation Information

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