Pathology small specimen collection, dehydration and embedding all-in-one machine

Abstract

The present invention provides an all-in-one machine for sampling, dehydrating and embedding pathological small specimens, and relates to the field of pathological embedding equipment. The all-in-one machine for sampling, dehydrating and embedding pathological small specimens comprises an automatic dehydrator, a paraffin embedding machine, an embedding machine body, a material transportation line, a centrifugal operation device, a hot-melt sealing device, an information processing device, and a plurality of specimen collection bottles. The all-in-one machine realizes full-automatic operation from sampling to final paraffin embedding through mutual integration and coordinated use of a plurality of devices, reduces manual intervention, avoids direct contact of medical personnel with harmful substances, and greatly improves the safety of operation. At the same time, the use of an information scanning device and a photographing device ensures accurate recording and tracking of the information of each specimen, the precise operation of a mechanical grabbing arm and a clamping device reduces the risk of specimen loss, and the automated process eliminates the uncertainty and error caused by human factors, thereby improving the reliability and accuracy of the overall work.

Description

Technical Field

[0001] The invention relates to the field of pathological embedding equipment, in particular to an all-in-one machine for collecting, dehydrating and embedding small pathological specimens. Background Art

[0002] With the development of society, automation technology has become inevitable and a social consensus. Various electrical appliances are increasingly developing in the direction of being easy to use, space-saving, safe and efficient, and multi-functional. Tumors seriously threaten human life and health. Pathology, as the gold standard for diagnosis, is essential for accuracy. The sampling, dehydration and embedding of small pathological specimens are the top priorities in pathological work. At present, the sampling of small pathological specimens still relies on manual work (small specimens, not large specimens, such as gastroscopic specimens, liver puncture or gastroscope, bronchoscope and other tissues or tissues with a diameter of less than 2cm), and there is a lack of automated instruments that can free doctors' hands. This situation not only limits the improvement of work efficiency, but also brings many inconveniences to medical staff. Doctors need to directly contact formaldehyde fixative when taking pathological specimens, which poses a potential risk to health. Each specimen needs to go through a strict verification procedure to ensure that the information is accurate, which increases the complexity and time cost of the operation. It is particularly difficult to collect and manage small specimens. The slightest carelessness may lead to the loss or confusion of specimens, which seriously affects the quality of subsequent analysis and reduces the efficiency of the process from pathological sampling to embedding.

[0003] Therefore, it is necessary to provide a new pathological small specimen collection, dehydration and embedding all-in-one machine to solve the above technical problems. Summary of the invention

[0004] In order to solve the above technical problems, the present invention provides an all-in-one machine for collecting, dehydrating and embedding small pathological specimens.

[0005] The pathological small specimen sampling, dehydration and embedding integrated machine provided by the present invention comprises: an automatic dehydration machine for dehydrating the pathological small specimen and a paraffin embedding machine for dehydrating the pathological small specimen; It also includes an embedding machine body, a material transport line, a centrifugal operation device, a hot-melt sealing device, an information processing device, and a plurality of specimen collection bottles, wherein the centrifugal operation device, the automatic dehydrator, and the material transport line are all located inside the embedding machine body, and the material transport line and the automatic dehydrator are installed around the centrifugal operation device in a U-shaped manner, and the material transport line and the automatic dehydrator are connected respectively through a material transport plate and two flow guides; The paraffin embedding machine and the hot melt sealing device are both installed above the material transport line and inside the embedding machine body, and the top of the information processing device is detachably connected to the top of the embedding machine body; When the specimen collection bottle passes through the material transport line and reaches below the centrifugal operation device, the centrifugal operation device will clamp the specimen collection bottle and rotate it; The specimen collection bottle includes a collection bottle body and a collection bottle cap. The top of the collection bottle body and the bottom of the collection bottle cap are threadedly connected to each other. A filtrate hopper is provided inside the collection bottle cap. An information label is provided on the surface of the collection bottle body. The top of the collection bottle cap fits with the top of the material transport line.

[0006] Preferably, a feed port and a discharge port are respectively provided on one side surface of the embedding machine body, and one end of the material transport line adjacent to the feed port is connected to the feed port via a feed plate, and the feed plate is arranged in a state where the feed port is inclined toward the material transport line, and a temporary storage box is fixedly provided below one end of the material transport line adjacent to the discharge port, and one end of the temporary storage box is in close contact with and overlaps the discharge port, and two inspection door panels are provided on the other surface of the embedding machine body, and both of the two inspection door panels are rotatably connected to the embedding machine body.

[0007] Preferably, the material transport line includes a centrifugal conveyor belt, a sealed conveyor belt, an embedded conveyor belt and a material collection platform, and the centrifugal conveyor, the sealed conveyor belt, the embedded conveyor belt and the material collection platform are respectively installed in a U-shape around the centrifugal operating device, one end of the centrifugal conveyor belt and one end of the feed plate are overlapped with each other, the other end of the centrifugal conveyor belt is connected to one end of the sealed conveyor belt through a sliding plate, and the other end of the sealed conveyor belt is connected to the top of the material collection platform through a discharge plate, one side of the top of the material collection platform is fixedly connected to the two transport members, and the top of the embedded conveyor belt is in contact with the bottom of the transport plate.

[0008] Preferably, the centrifugal operation device includes a mechanical grabbing arm and a clamping member, the mechanical grabbing arm is located at the center of the embedding machine body, the clamping member is fixedly installed on the top surface of the centrifugal conveyor belt, and when the collecting bottle body and the collecting bottle cap pass through the centrifugal conveyor belt to reach the bottom of the mechanical grabbing arm, the mechanical grabbing arm centrifugally rotates the collecting bottle body and the collecting bottle cap, and after the mechanical grabbing arm is centrifugally rotated, the clamping member will cooperate with the mechanical grabbing arm to separate the collecting bottle body and the collecting bottle cap.

[0009] Preferably, the hot melt sealing device includes a hot melt sealing machine and two guide components, the bottom end of the hot melt sealing machine is fixedly connected to the top end of the sealing conveyor belt, the two guide components are located inside the bottom end of the hot melt sealing machine and are arranged opposite to each other, and at the same time, the ends of the two guide components that are away from each other are respectively rotatably connected to the inner side walls of the bottom end of the hot melt sealing machine.

[0010] Preferably, the information processing device includes a scanning component and a photographing component, the tops of the scanning component and the photographing component are detachably connected to the top of the interior of the embedding body through a plurality of connecting bolts, and the scanning component is located above the centrifugal conveyor belt, and the photographing component is located above the sealed conveyor belt.

[0011] Preferably, the material collecting platform comprises a placing platform and a collecting plate, the collecting plate is located on the top of the placing platform, and the bottom end of the collecting plate is in contact with the top end of the placing platform.

[0012] Preferably, the mechanical grabbing arm comprises a clamping assembly, a moving arm and a rotating table, the clamping assembly is rotatably connected to one end of the moving arm, and the bottom of the moving arm is fixedly connected to the top of the rotating table.

[0013] Preferably, the clamping device includes a pushing motor, a driving rod and two clamping claws, the two clamping claws are arranged opposite to each other, one end of the two clamping claws are meshed with the surface of the driving rod, the other end of the driving rod is fixedly connected to the output end of the pushing motor, and the bottom end of the pushing motor is fixedly connected to the top of the centrifugal conveyor belt.

[0014] Compared with the related art, the pathological small specimen sampling, dehydration and embedding integrated machine provided by the present invention has the following beneficial effects: 1. Through the integration of automatic dehydration machine, paraffin embedding machine, material transportation line, hot-melt sealing device, information processing device, centrifugal operation device and specimen collection bottle, the all-in-one machine realizes full automation from sampling to final paraffin embedding, reduces manual intervention, avoids direct contact of medical staff with harmful substances, and greatly improves the safety of operation. At the same time, the use of information scanning device and camera device ensures the accurate recording and tracking of the information of each specimen. The precise operation of mechanical grabbing arm and clamping device reduces the risk of specimen loss. The automated process eliminates the uncertainty and errors caused by human factors and improves the reliability and accuracy of the overall work.

[0015] 2. The efficient hot-melt sealing device, intelligent control system and optimized workflow enable each link to run efficiently, shorten processing time, and improve sample quality and consistency. In particular, the patented technology of the paraffin embedding machine ensures gentle tissue processing to prevent damage and protects tissue structural integrity through precise temperature control. At the same time, the all-in-one machine integrates components such as automatic dehydrator, paraffin embedding machine and material transportation line to achieve functional integration, greatly saving laboratory space. At the same time, it supports high-throughput processing, ensures rapid turnover, and improves and reduces the efficiency of the process from pathological sampling to embedding.

[0016] 3. The all-in-one machine supports multiple pressure options and personalized settings, and can adapt to the processing needs of different types of small specimens, such as gastroscopy specimens, liver biopsy or bronchoscopy tissues. Small specimens with smaller diameters can also be properly processed, enhancing the flexibility and applicability of the system. At the same time, the built-in information scanning device, shooting device and special software support full-process data management and traceability, ensuring that all operation records are accurate, facilitating audit tracking and quality control. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 A schematic diagram of the planar structure of the integrated machine for collecting, dehydrating and embedding small pathological specimens provided by the present invention; Figure 2 A schematic diagram of the overall structure of the embedding body provided by the present invention; Figure 3 A schematic diagram of the overall structure of the centrifugal conveyor belt, mechanical grabbing arm and clamping member provided by the present invention; Figure 4 for Figure 3 The enlarged view of point A is shown; Figure 5 A schematic diagram of the disassembly structure of the specimen collection bottle provided by the present invention; Figure 6 A schematic diagram of the overall structure of the hot melt sealing machine and two guide components provided by the present invention; Figure 7 A schematic diagram of the partial structure of the pathological small specimen collection, dehydration and embedding integrated machine from another perspective provided by the present invention; Figure 8 The present invention provides an overall structural schematic diagram of an embedding body and two flow guide bodies; Fig. 9 A schematic diagram of the overall structure of the embedding conveyor belt and the paraffin embedding machine provided by the present invention; Fig.10 This is a schematic diagram of the overall structure of the temporary storage box provided by the present invention.

[0018] Numbers in the figure: 1. Automatic dehydration machine; 2. Paraffin embedding machine; 3. Embedding machine body; 4. Hot melt sealing device; 5. Material transport plate; 6. Diversion body; 7. Specimen collection bottle; 8. Collection bottle body; 9. Collection bottle cap; 10. Filtrate bucket; 11. Feed inlet; 12. Discharge outlet; 13. Feed plate; 14. Temporary storage box; 15. Inspection door; 16. Centrifugal conveyor belt; 17. Sealed conveyor belt; 18. Embedding transport Belt; 19, material collecting table; 20, sliding plate; 21, unloading plate; 22, mechanical grabbing arm; 23, clamping member; 24, hot melt sealing machine; 25, guiding member; 26, scanning member; 27, shooting member; 28, placing table; 29, collecting plate; 30, clamping assembly; 31, moving arm; 32, rotating table; 33, pushing motor; 34, driving rod; 35, clamping claw; 36, stop bar. DETAILED DESCRIPTION

[0019] The present invention will be further described below in conjunction with the accompanying drawings and implementation modes.

[0020] Please refer to Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Fig. 9 as well as Fig.10 ,in, Figure 1 A schematic diagram of the planar structure of the integrated machine for collecting, dehydrating and embedding small pathological specimens provided by the present invention; Figure 2 A schematic diagram of the overall structure of the embedding body provided by the present invention; Figure 3 A schematic diagram of the overall structure of the centrifugal conveyor belt, mechanical grabbing arm and clamping member provided by the present invention; Figure 4 for Figure 3 The enlarged view of point A is shown; Figure 5 A schematic diagram of the disassembly structure of the specimen collection bottle provided by the present invention; Figure 6 A schematic diagram of the overall structure of the hot melt sealing machine and two guide components provided by the present invention; Figure 7 A schematic diagram of the partial structure of the pathological small specimen collection, dehydration and embedding integrated machine from another perspective provided by the present invention; Figure 8 The present invention provides an overall structural schematic diagram of an embedding body and two flow guide bodies; Fig. 9 A schematic diagram of the overall structure of the embedding conveyor belt and the paraffin embedding machine provided by the present invention; Fig.10 This is a schematic diagram of the overall structure of the temporary storage box provided by the present invention.

[0021] In the specific implementation process, Figure 1-Figure 10As shown, the pathological small specimen sampling, dehydration and embedding integrated machine provided by the present invention includes an automatic dehydration machine 1 for dehydrating small pathological specimens and a paraffin embedding machine 2 for dehydrating small pathological specimens. Among them, the paraffin embedding machine can be of the following model: Leica fully automatic tissue packing machine HistoCore Arcadia, which is a highly efficient equipment designed for pathological laboratories, combining advanced technology and humanized design, aiming to simplify the workflow and improve the quality of sample processing. The machine realizes fully automated operation from receiving dehydrated tissue to finally completing paraffin embedding without manual intervention, thereby greatly reducing the impact of human factors on experimental results, and optimizes a series of steps such as sample transmission, positioning, cutting and embedding through integrated system design, significantly improving work efficiency; the automatic dehydration machine can be of the following model: Leica ASPS type, which can reliably process the designed pathological laboratory equipment and has significant advantages. It can process up to embedding boxes, suitable for high-throughput laboratories, and ensures rapid turnover. Equipped with a corrosion-resistant color touch screen, it provides intuitive operation and online help to simplify workflow. Integrated intelligent software supports reagent management and fast program startup, improving sample quality and optimizing cost-effectiveness.

[0022] In a specific embodiment, Figure 1 As shown, the pathological small specimen sampling, dehydration and embedding integrated machine of the present invention is of a square design as a whole, and each structure adopts a surround layout, which makes rational use of space, so that the machine has a large space utilization rate and a compact structure, which is suitable for, wherein the automatic dehydrator 1 is located on the side of the placement table 28 away from the material transportation line.

[0023] The pathological small specimen sampling, dehydration and embedding integrated machine provided by the present invention also includes an embedding body 3, a material transportation line, a centrifugal operation device, a hot melt sealing device 4, an information processing device, and a plurality of specimen collection bottles 7. The centrifugal operation device, the automatic dehydrator 1 and the material transportation line are all located inside the embedding body 3, and the material transportation line and the automatic dehydrator 1 are installed around the centrifugal operation device in a U-shaped manner, and the material transportation line and the automatic dehydrator 1 are connected to each other through a material transport plate 5 and two flow guides 6 respectively.

[0024] The paraffin embedding machine 2 and the hot melt sealing device 4 are both installed above the material transport line and inside the embedding machine body 3, and the top of the information processing device is detachably connected to the top of the embedding machine body 3.

[0025] When the specimen collection bottle 7 reaches below the centrifugal operation device through the material transport line, the centrifugal operation device will clamp the specimen collection bottle 7 and rotate it.

[0026] The specimen collection bottle 7 includes a collection bottle body 8 and a collection bottle cap 9. The top of the collection bottle body 8 and the bottom of the collection bottle cap 9 are threadedly connected to each other. A filtrate funnel 10 is provided inside the collection bottle cap 9. An information label is provided on the surface of the collection bottle body 8. The top of the collection bottle cap 9 fits with the top of the material transport line.

[0027] In a specific embodiment, micropores are provided on the surface of the filtrate bucket 10, and the size of the micropores is preferably within 0.05-0.1 cm, which can not only meet the water permeability requirements, but also protect the specimens, and prevent the specimens from being damaged and leaking out during centrifugation due to the micropores being too large. In addition, the material of the filtrate bucket 10 also needs to be able to withstand centrifugal strength, and preferably can be made of medical grade plastic or plastic material.

[0028] In a specific embodiment, the filtrate bucket 10 can be separated from the inside of the bottle body 8. When embedding, the filtrate bucket 10 can be embedded together with the small specimen as needed, or the small specimen can be poured out of the filtrate bucket into the embedding machine for embedding. In order to meet the embedding requirements, the height and diameter of the filtrate bucket are preferably 3-5 cm.

[0029] A feed port 11 and a discharge port 12 are respectively provided on one side surface of the embedding body 3. One end of the material transport line adjacent to the feed port 11 is connected to the feed port 11 through a feed plate 13. The feed plate 13 is arranged in a state where the feed port 11 is inclined toward the material transport line. A temporary storage box 14 is fixedly provided below one end of the material transport line adjacent to the discharge port 12. One end of the temporary storage box 14 is in close contact with and overlaps the discharge port 12. Two inspection door panels 15 are provided on the other surface of the embedding body 3. The two inspection door panels 15 are rotatably connected to the embedding body 3.

[0030] In a specific embodiment, the interior of the temporary storage box 14 is inclined toward the discharge port 12, so that the collection bottle bodies 8 and the collection bottle caps 9 can be moved toward the discharge port 12 under the influence of the inclination angle of the temporary storage box 14 when they enter the temporary storage box 14 after use. At the same time, a baffle 36 is provided at one end of the temporary storage box 14 near the discharge port 12 to prevent the collection bottle bodies 8 and the collection bottle caps 9 from falling when they move toward the discharge port 12 along the inclination angle of the interior of the temporary storage box 14.

[0031] The material transport line includes a centrifugal conveyor belt 16, a sealed conveyor belt 17, an embedded conveyor belt 18 and a material collection platform 19. The centrifugal conveyor belt, the sealed conveyor belt 17, the embedded conveyor belt 18 and the material collection platform 19 are respectively installed in a U-shaped manner around the centrifugal operating device. One end of the centrifugal conveyor belt 16 is overlapped with one end of the feed plate 13, and the other end of the centrifugal conveyor belt 16 is connected to one end of the sealed conveyor belt 17 through a sliding plate 20. The other end of the sealed conveyor belt 17 is connected to the top of the material collection platform 19 through a discharge plate 21. One side of the top of the material collection platform 19 is fixedly connected to the two transport members, and the top of the embedded conveyor belt 18 is in contact with the bottom of the transport plate 5.

[0032] In a specific embodiment, the material collecting platform 19 includes a placing platform 28 and a collecting plate 29 . The collecting plate 29 is located on the top of the placing platform 28 , and the bottom end of the collecting plate 29 is in contact with the top end of the placing platform 28 .

[0033] The centrifugal operation device includes a mechanical grabbing arm 22 and a clamping member 23. The mechanical grabbing arm 22 is located at the center of the embedding body 3. The clamping member 23 is fixedly installed on the top surface of the centrifugal conveyor belt 16. When the collection bottle body 8 and the collection bottle cap 9 pass through the centrifugal conveyor belt 16 and reach the bottom of the mechanical grabbing arm 22, the mechanical grabbing arm 22 will centrifugally rotate the collection bottle body 8 and the collection bottle cap 9. After the mechanical grabbing arm 22 is centrifugally rotated, the clamping member 23 will cooperate with the mechanical grabbing arm 22 to separate the collection bottle body 8 and the collection bottle cap 9.

[0034] In a specific embodiment, the mechanical grabbing arm 22 includes a clamping assembly 30, a moving arm 31 and a rotating table 32. The clamping assembly 30 is rotatably connected to one end of the moving arm 31, and the bottom of the moving arm 31 is fixedly connected to the top of the rotating table 32.

[0035] The clamping device includes a pushing motor 33, a driving rod 34 and two clamping claws 35. The two clamping claws 35 are arranged opposite to each other, and one end of the two clamping claws 35 is meshed with the surface of the driving rod 34. The other end of the driving rod 34 is fixedly connected to the output end of the pushing motor 33, and the bottom end of the pushing motor 33 is fixedly connected to the top of the centrifugal conveyor belt 16.

[0036] The hot melt sealing device 4 includes a hot melt sealing machine 24 and two guide components 25. The bottom end of the hot melt sealing machine 24 is fixedly connected to the top end of the sealing conveyor belt 17. The two guide components 25 are located inside the bottom end of the hot melt sealing machine 24 and are arranged opposite to each other. At the same time, the ends of the two guide components 25 that are away from each other are respectively rotatably connected to the inner side walls of the bottom end of the hot melt sealing machine 24.

[0037] In a specific embodiment, the hot melt sealing machine 24 adopts the model: Julun jq-sealing machine, which has an electronic control system to ensure that the temperature and speed during the sealing process are accurately controlled, which not only improves work efficiency but also reduces energy consumption; the rapid heating function can shorten the preheating time and further improve production efficiency. Users can easily set parameters to adapt to different materials and packaging requirements.

[0038] The information processing device includes a scanning component 26 and a photographing component 27. The tops of the scanning component 26 and the photographing component 27 are detachably connected to the top of the inner part of the embedding body 3 through a plurality of connecting bolts. The scanning component 26 is located above the centrifugal conveyor belt 16, and the photographing component is located above the sealing conveyor belt 17. In a specific embodiment, the scanning component 26 and the shooting component 27 are both equipped with wireless network cards, which can interact with devices outside the embedding body 3 to collect and archive the collected information, so that it can be automatically managed and archived.

[0039] The working principle provided by the present invention is as follows: When processing small specimens from cases, first place the small specimens inside the collection bottle body 8, then pour in 4% neutral buffered formaldehyde solution as a fixative, and the total amount of the fixative does not exceed the volume of the bottle cap. At this time, move the collection bottle cap 9 together with the filtrate bucket 10 toward the collection bottle body 8 and rotate the threaded connection. At this time, write the specimen information on the information label on the surface of the collection bottle body 8. At this time, repeat the above operation inside multiple specimen collection bottles 7, place all the tissues that need to be embedded inside multiple specimen collection bottles 7, invert the multiple specimen collection bottles 7, and open the feed port 11 on one side of the embedding body 3 at the same time, so that the collection bottle cap 9 can be placed on the feed plate 13 for convenience. At this time, the specimen collection bottle 7 will be tilted along the feed plate 13 toward the centrifugal conveyor belt 1 6 moves above to transport the specimen collection bottle 7. When the centrifugal conveyor belt 16 drives the specimen collection bottle 7 to move, the scanning component 26 will scan and collect the information label adhered to the collection bottle body 8. At this time, when the specimen collection bottle 7 passes through the centrifugal conveyor belt 16 and reaches below the mechanical grabbing arm 22, the mechanical grabbing arm 22 clamps the specimen collection bottle 7. At this time, when the mechanical grabbing arm 22 works, the centrifugal conveyor belt 16 will stop transporting, and rotate between the clamping component 30 and the moving arm 31, thereby causing the specimen collection bottle 7 to rotate by centrifugal force, and the fixing liquid inside the specimen collection bottle 7 is rotated and collected to the inside of the collection bottle cap 9 through the micropores on the surface of the filtrate bucket 10, and then the liquid is removed by rotation. When the liquid is removed by rotation, the output end of the driving motor 33 will bring The driving rod 34 is driven to move toward the two clamping claws 35, so that the two clamping claws 35 are unfolded. At this time, the clamping assembly 30 places the collection bottle cap 9 between the two clamping claws 35. At this time, the output end of the push motor 33 is driven in the opposite direction to drive the driving rod 34 to move away from the two clamping claws 35, so that the two clamping claws 35 are clamped close to each other. At this time, the clamping assembly 30 is driven again to open the knobs between the collection bottle body 8 and the collection bottle cap 9. At this time, the collection bottle body 8 can be placed in the temporary storage box 14 through the mechanical grabbing arm 22. The clamping assembly 30 stops working, and the material transportation line will resume the transportation function. At this time, the clamping member 23 places the collection bottle cap 9 back to the top of the centrifugal conveyor belt 16, and the centrifugal conveyor belt 16 cooperates with the sliding plate 20 , so that the collecting bottle cap 9 reaches the top of the sealing conveyor belt 17. At this time, the shooting component 27 at the top of the material transportation line takes a photo of the tissue specimen inside the collecting bottle cap 9 for preservation. The collecting bottle cap 9 moves along the sealing conveyor belt 17 until it enters the inside of the guide component 25. At this time, the guide component 25 will guide the position of the collecting bottle cap 9. At this time, when the sensing device inside the hot melt sealing machine 24 detects the presence of the collecting bottle cap 9, the hot melt soldering iron can be lowered to drive the plastic sealing film to seal the cover of the collecting bottle cap 9. The guide component 25 rotates to release the limit, so that the collecting bottle cap 9 enters the inside of the collecting plate 29 along the unloading plate 21. When the collecting plate 29 collects a sufficient amount of specimens, it will slide along the surface of the two guide bodies 6 to the top of the automatic dehydrator 1.After entering the automatic dehydrating machine 1, different dehydrating processes are adopted according to different tissue types, and then the sample dehydrating process of baking dehydration and solvent dehydration is completed. The dehydrated tissue small specimens will be moved from the material transport plate 5 on one side of the automatic dehydrating machine 1 to the upper part of the embedding conveyor belt 18 together with the collecting bottle cap 9. At this time, the collecting bottle cap 9 will bring the dehydrated tissue small specimens to the paraffin embedding machine 2 for paraffin embedding. After the paraffin embedding process, the specimens will arrive at the temporary storage box 14. At this time, the temporary storage box 14 is in a state of The arrangement is tilted toward the discharge port 12, so that when the collection bottle body 8 and the collection bottle cap 9 enter the temporary storage box 14 after use, they can be affected by the tilt angle of the temporary storage box 14 and move toward the discharge port 12. At the same time, a retaining bar 36 is provided at one end of the temporary storage box 14 near the discharge port 12 to prevent the collection bottle body 8 and the collection bottle cap 9 from falling when they move toward the discharge port 12 along the tilt angle inside the temporary storage box 14. The processing of small case specimens is completed through the mutual linkage and cooperation between the above-mentioned device components. In the whole process of the present invention, only the embedding operation may require manual intervention, and other operations can be performed automatically by the machine, which greatly improves the operation of small pathological specimens. The above descriptions are merely embodiments of the present invention and are not intended to limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the present invention specification and drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. Pathological small specimen collection, dehydration and embedding all-in-one machine, including: An automatic dehydrating machine (1) for dehydrating small pathological specimens and a paraffin embedding machine (2) for dehydrating small pathological specimens, characterized in that they also include: an embedding machine body (3), a material transport line, a centrifugal operation device, a hot melt sealing device (4), an information processing device, and a plurality of specimen collection bottles (7), wherein the centrifugal operation device, the automatic dehydrating machine (1) and the material transport line are all located inside the embedding machine body (3), and the material transport line and the automatic dehydrating machine (1) are installed around the centrifugal operation device in a U-shaped manner, and the material transport line and the automatic dehydrating machine (1) are connected to each other via a material transport plate (5) and two flow guides (6); The paraffin embedding machine (2) and the hot melt sealing device (4) are both installed above the material transport line and inside the embedding machine body (3), and the top of the information processing device is detachably connected to the top of the embedding machine body (3); When the specimen collection bottle (7) passes through the material transport line and reaches below the centrifugal operation device, the centrifugal operation device clamps the specimen collection bottle (7) and rotates it; The specimen collection bottle (7) comprises a collection bottle body (8) and a collection bottle cap (9); the top of the collection bottle body (8) and the bottom of the collection bottle cap (9) are threadedly connected to each other; a filtrate hopper (10) is provided inside the collection bottle cap (9); an information label is provided on the surface of the collection bottle body (8); and the top of the collection bottle cap (9) fits with the top of the material transport line.

2. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 1, characterized in that: A feed port (11) and a discharge port (12) are respectively provided on one side surface of the embedding machine body (3); an end of the material transport line adjacent to the feed port (11) is connected to the feed port (11) via a feed plate (13); the feed plate (13) is arranged in a slanted manner from the feed port (11) to the material transport line; a temporary storage box (14) is fixedly provided below an end of the material transport line adjacent to the discharge port (12); one end of the temporary storage box (14) is overlapped with the discharge port (12); and two inspection door panels (15) are provided on the other surface of the embedding machine body (3); the two inspection door panels (15) are both rotatably connected to the embedding machine body (3).

3. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 2, characterized in that: The material transport line comprises a centrifugal conveyor belt (16), a sealing conveyor belt (17), an embedding conveyor belt (18) and a material collection platform (19). The centrifugal conveyor, the sealing conveyor belt (17), the embedding conveyor belt (18) and the material collection platform (19) are respectively mounted in a U-shaped manner around the centrifugal operation device. One end of the centrifugal conveyor belt (16) and one end of the feed plate (13) are overlapped with each other, and the other end of the centrifugal conveyor belt (16) is connected to one end of the sealing conveyor belt (17) through a sliding plate (20). The other end of the sealing conveyor belt (17) is connected to the top of the material collection platform (19) through a discharge plate (21). One side of the top of the material collection platform (19) is fixedly connected to the two transport members, and the top of the embedding conveyor belt (18) is in contact with the bottom of the transport plate (5).

4. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 3, characterized in that: The centrifugal operation device comprises a mechanical grabbing arm (22) and a clamping member (23), wherein the mechanical grabbing arm (22) is located at the center of the embedding machine body (3), and the clamping member (23) is fixedly installed on the top surface of the centrifugal conveyor belt (16). When the collecting bottle body (8) and the collecting bottle cap (9) pass through the centrifugal conveyor belt (16) and reach below the mechanical grabbing arm (22), the mechanical grabbing arm (22) centrifugally rotates the collecting bottle body (8) and the collecting bottle cap (9). After the mechanical grabbing arm (22) is centrifugally rotated, the clamping member (23) cooperates with the mechanical grabbing arm (22) to separate the collecting bottle body (8) and the collecting bottle cap (9).

5. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 4, characterized in that: The hot melt sealing device (4) comprises a hot melt sealing machine (24) and two guide components (25), the bottom end of the hot melt sealing machine (24) is fixedly connected to the top end of the sealing conveyor belt (17), the two guide components are located inside the bottom end of the hot melt sealing machine (24) and are arranged opposite to each other, and the ends of the two guide components (25) that are away from each other are respectively rotatably connected to the inner side wall of the bottom end of the hot melt sealing machine (24).

6. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 5, characterized in that: The information processing device comprises a scanning component (26) and a photographing component (27), the top ends of the scanning component (26) and the photographing component (27) being detachably connected to the top end of the interior of the embedding body (3) via a plurality of connecting bolts, and the scanning component (26) is located above the centrifugal conveyor belt (16), and the photographing component is located above the sealing conveyor belt (17).

7. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 5, characterized in that: The material collecting platform (19) comprises a placing platform (28) and a collecting plate (29), wherein the collecting plate (29) is located on the top of the placing platform (28), and the bottom end of the collecting plate (29) is in contact with the top end of the placing platform (28).

8. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 5, characterized in that: The mechanical grabbing arm (22) comprises a clamping assembly (30), a moving arm (31) and a rotating table (32); the clamping assembly (30) is rotationally connected to one end of the moving arm (31); and the bottom of the moving arm (31) is fixedly connected to the top of the rotating table (32).

9. The pathological small specimen sampling, dehydration and embedding integrated machine according to claim 5, characterized in that: The clamping device comprises a driving motor (33), a driving rod (34) and two clamping claws (35), wherein the two clamping claws (35) are arranged opposite to each other, one end of the two clamping claws (35) is meshed with the surface of the driving rod (34), the other end of the driving rod (34) is fixedly connected to the output end of the driving motor (33), and the bottom end of the driving motor (33) is fixedly connected to the top end of the centrifugal conveyor belt (16).

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