External traditional Chinese medicine ointment for treating senile functional constipation and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine ointment, in particular to external traditional Chinese medicine ointment for treating senile functional constipation and a preparation method thereof, and the external traditional Chinese medicine ointment comprises the following components: angelica sinensis, radix achyranthis bidentatae, sargentgloryvine stem, black prepared common monkshood daughter root, pericarpium citri reticulatae, immature bitter orange, astragalus membranaceus, bighead atractylodes rhizome, safflower, peach kernel, notopterygium root, rheum officinale, clove, elecampane, asarum and auxiliary guide materials. The main action mechanism of the external traditional Chinese medicine ointment prepared by the invention is that the treatment effect of improving the senile functional constipation is achieved by absorbing active ingredients of medicines through skin, and due to the barrier action of the skin, the traditional medicine ingredients are difficult to effectively permeate through the skin to be absorbed, so that the use effect is limited; according to the traditional Chinese medicine ointment disclosed by the invention, the components of the traditional Chinese medicine ointment are greatly improved, and the effect of specially-made auxiliary guiding materials is introduced through the matching effect of the components, so that the effect of the active components of the prepared traditional Chinese medicine ointment penetrating through a skin barrier can be greatly improved, and the problem of senile functional constipation is greatly improved through continuous stimulation on acupuncture points.

Description

Technical Field

[0001] The invention relates to the technical field of Chinese medicinal ointments, in particular to an external Chinese medicinal ointment for treating functional constipation in the elderly and a preparation method thereof. Background Art

[0002] Functional constipation (FC) refers to constipation caused by secondary factors other than organic lesions of the intestine, systemic diseases and drugs. It is characterized by difficulty in defecation, reduced frequency of defecation or incomplete defecation, accompanied by abdominal distension and abdominal pain. It is one of the common functional gastrointestinal diseases of the digestive system, with the characteristics of stubborn symptoms and recurrent attacks. Functional constipation is a common clinical disease that can occur in any age group, with a global incidence of about 14%. Domestic epidemiological surveys and studies have found that the incidence of FC in my country is about 4% to 10%, with more women than men and higher elderly people than young people. The incidence of the elderly is as high as 18%. With the development of my country's economy, the accelerated pace of life of urban and rural residents, changes in dietary structure, high-intensity work and study burdens, and bad living habits such as staying up late, the incidence of the disease has been increasing year by year, and the incidence population is also becoming younger. Although FC does not involve organic lesions, it brings inconvenience to people's daily life and work. Long-term constipation can lead to abdominal distension, abdominal pain, hemorrhoids, anal fissures, intestinal polyps, and may even increase the risk of rectal cancer. In addition, straining during defecation can cause myocardial ischemia and a decrease in peripheral blood volume, which can easily induce cardiovascular and cerebrovascular diseases such as angina pectoris, myocardial infarction, and cerebral infarction. FC not only causes patients to suffer physical pain, but also can lead to psychological problems such as depression and anxiety. In severe cases, it can even become a mental illness, which brings great harm to the lives and mental health of contemporary people.

[0003] Functional constipation in the elderly is a common health problem among the elderly. It is a type of functional bowel disease, and its main manifestations are difficulty in defecation, reduced frequency of bowel movements, or a feeling of incomplete defecation.

[0004] Functional constipation in the elderly can be divided into three categories: Slow-transmission constipation: mainly manifested by reduced bowel movement, hard and dry stool, and labored defecation. This is usually caused by weakened intestinal peristalsis. Outlet obstruction constipation: mainly manifested by difficulty in defecation even though the stool is not dry, or a feeling of incomplete defecation, as well as a feeling of anal obstruction and falling during defecation. This situation is more common in women and may be related to the relaxation of the abdominal wall and pelvic floor muscles. Mixed constipation: patients have symptoms of delayed colon transmission and anorectal defecation disorders at the same time.

[0005] Functional constipation in the elderly not only affects the quality of life of the elderly, but may also bring a series of serious health hazards, including: Digestive system problems: Long-term constipation may lead to digestive system diseases such as anal fissures, hemorrhoids, and intestinal obstruction. Cardiovascular and cerebrovascular accidents: Excessive force during defecation can increase blood pressure and increase the risk of cardiovascular and cerebrovascular events, such as myocardial infarction and stroke. Psychological problems: Long-term constipation can cause physical discomfort and psychological pressure to the elderly, and easily lead to psychological problems such as anxiety and depression.

[0006] In summary, functional constipation in the elderly is a health problem that needs to be taken seriously. However, existing technologies usually use medication to treat functional constipation in the elderly, which has limited effects and may also have other side effects. After stopping the medication, the constipation problem will recur.

[0007] Based on this, the present invention provides an external Chinese medicinal ointment for treating functional constipation in the elderly to solve the corresponding problems. Summary of the invention

[0008] In view of the problems existing in the prior art, the present invention provides an external Chinese medicinal ointment for treating functional constipation in the elderly and a preparation method thereof.

[0009] To achieve the above object, the present invention provides the following technical solutions:

[0010] An external Chinese medicinal ointment for treating functional constipation in the elderly, comprising the following ingredients by weight:

[0011] 30-40 parts of angelica sinensis, 20-25 parts of Achyranthes bidentata, 1-3 parts of Sargentodoxa chinensis, 3-5 parts of Heishunpian, 2-4 parts of dried tangerine peel, 3-5 parts of immature bitter orange, 1-3 parts of astragalus, 6-9 parts of atractylodes macrocephala, 0.1-0.3 parts of safflower, 1-1.5 parts of peach kernel, 4-7 parts of notopterygium wilfordii, 2-3 parts of rhubarb, 4-9 parts of cloves, 3-6 parts of costusroot, 2-3 parts of asarum, and 3-4 parts of auxiliary materials.

[0012] As a further technical solution, the auxiliary material is prepared from Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora;

[0013] Among them, the mixed mass ratio of Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora is 18:15:12.

[0014] As a further technical solution, the auxiliary primer preparation method is:

[0015] Firstly, Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora are mixed and crushed respectively, and then sieved through an 80-mesh sieve to obtain a mixed powder;

[0016] Take the mixed powder, add water 10 times the mass of the mixed powder, soak at room temperature for 40 minutes, then heat to boiling, keep it slightly boiling for 20 minutes over low heat, let it stand for 1 hour, filter it, remove the filter residue, and obtain the filtrate;

[0017] The filtrate is canned and sealed, and then placed in a high pressure steam sterilizer for steam sterilization at 121°C for 30 minutes, and then cooled to room temperature;

[0018] Add the lyophilized powder of fermentation bacteria to the cooled filtrate, stir and mix evenly, and then shake and ferment in a shaker at 37° C. and 200 r / min for 48 hours to obtain a fermentation liquid;

[0019] Then the fermentation liquid is concentrated to 10% of the original volume to obtain the auxiliary feed.

[0020] As a further technical solution, the mass ratio of the filtrate and the fermentation bacteria freeze-dried powder is 100:2-3.

[0021] As a further technical solution, the fermented bacteria freeze-dried powder contains 3.5×10 8 CFU and animal Bifidobacterium freeze-dried powder 2.4×10 8 CFU.

[0022] A method for preparing an external Chinese medicinal ointment for treating functional constipation in the elderly comprises the following steps:

[0023] (1) Weigh the following ingredients by weight: Chinese Angelica, Achyranthes bidentata, Sargentodoxae, Heishun Pian, Tangerine Peel, Citrus Aurantium, Astragalus, Atractylodes, Carthamus tinctorius, Semen persicae, Notopterygium wilfordii, Rhubarb, Clove, Aucklandia lappa, Asarum, and auxiliary materials;

[0024] (2) Mixing: Add the above raw material components into a mixer and stir and mix for 20 minutes to obtain a uniform mixture;

[0025] Among them, the mixing and stirring speed is 200r / min;

[0026] (3) Crushing: adding the uniformly mixed material obtained above into a crusher for crushing, passing through a 60-mesh sieve to obtain a uniformly crushed material;

[0027] (4) decoction: add 15 times the mass of water to the uniformly pulverized material obtained above, heat to boiling, decoct over low heat for 4 hours, transfer to a vacuum impregnation reactor, vacuum impregnate for 2 hours, discharge, and obtain a decoction;

[0028] (5) Filtration and concentration:

[0029] The obtained decoction is filtered to remove the filter residue, and then concentrated to 10% of the original volume to obtain a concentrated paste, which is then filled, sealed, and sterilized.

[0030] As a further technical solution, the temperature of the vacuum impregnation is 40°C and the vacuum degree is 0.1Pa.

[0031] As a further technical solution, the sterilization is steam sterilization.

[0032] As a further technical solution, the steam sterilization time is 20 minutes and the temperature is 121°C.

[0033] The method of using external Chinese medicine ointment for treating functional constipation in the elderly is to evenly apply the Chinese medicine ointment on the preheated Bianstone Tai Chi ball, and then evenly apply the ointment on the Bianstone ball around the navel, up to Zhongwan acupoint, down to Guanyuan acupoint, and left and right to cover Daheng acupoint. It is advisable to apply the ointment 2cm more than the edge of the acupoint, and the thickness is the thickness of a 1 yuan coin. Massage Shenque, Zhongwan, Jianli, Tianshu, Guanyuan, Qihai, Daheng and other acupoints clockwise, and push and rub each acupoint. Pay attention to the patient's feelings at any time during the operation, and pay attention to protecting the patient's privacy. The temperature of the Bianstone Tai Chi ball is about 40℃~55℃ during operation, and the temperature can be adjusted. It is advisable for the patient to feel warm and comfortable. After 15 minutes of massage, apply a thermal film to the operation site to allow the effect of the Chinese medicine ointment to continue to penetrate through the skin. After 20 minutes, uncover the thermal film and wipe off the Chinese medicine ointment with a paper towel.

[0034] Compared with the prior art, the present invention has the following beneficial effects:

[0035] The main mechanism of action of the external Chinese medicine ointment prepared by the present invention is usually to achieve the therapeutic effect of improving functional constipation in the elderly by absorbing the active ingredients of the medicine through the skin. Due to the barrier function of the skin, it is difficult for traditional medicine ingredients to be effectively absorbed through the skin, resulting in limited use effects. Therefore, the present invention greatly improves the ingredients of the Chinese medicine ointment, through the coordinated effect of various ingredients, and introduces the effect of special auxiliary materials, thereby greatly improving the effect of the active ingredients of the prepared Chinese medicine ointment passing through the skin barrier, and through continuous stimulation of acupoints, integrating warmth, acupoint massage, and transdermal absorption of drugs, thereby greatly improving the problem of functional constipation in the elderly, shortening the defecation time, and improving the quality of life.

[0036] Among them, the angelica sinensis nourishes blood and moistens the intestine, the Achyranthes bidentata draws blood downward, and the Sargentophyllum tonifies the kidney and moistens the intestine, which are all monarch drugs; the Heishun Tablet penetrates dampness and releases heat, the Tangerine Peel raises yang and lifts the sunken, and the Citrus aurantium regulates qi and relaxes the intestine, which are all minister drugs; the Astragalus membranaceus replenishes qi and relieves constipation, the Atractylodes macrocephala strengthens the spleen and relieves constipation, the Carthamus tinctorius replenishes qi and promotes the production of body fluid, the Peach Kernel promotes blood circulation and moistens the intestine, and the Notopterygium wilfordii dispels wind and overcomes dampness, which are all adjuvant drugs; the Rhubarb has the functions of purging and attacking accumulation, the Clove moistens the intestine and relieves constipation, the Aucklandia lappa warms yang and relieves constipation, and the Asarum dispels cold and opens the orifices, and the auxiliary materials are used as guiding drugs, and the whole prescription is reasonably compatible, and the active ingredients of these drugs enter the body through the skin, play a therapeutic effect on improving functional constipation in the elderly, and fundamentally improve the efficacy for functional constipation in the elderly.

[0037] The Chinese medicinal ointment prepared by the invention can stimulate specific acupoints by ironing and massaging these acupoints to play the role of warming and unblocking meridians, regulating qi and blood, and regulating qi, thereby assisting in improving constipation symptoms.

[0038] The coordinated action of the various components of the Chinese medicinal ointment of the present invention can improve the gastric emptying rate and the small intestinal propulsion rate, thereby promoting gastrointestinal motility. Under the effect of improving gastrointestinal motility, it can further improve constipation, reduce the difficulty of defecation, and shorten the defecation time. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0040] Figure 1 This is a statistical chart of the defecation time scores of each group in the experiment. DETAILED DESCRIPTION

[0041] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0042] Apply the topical Chinese medicine ointment for treating functional constipation in the elderly on the preheated Bianstone Tai Chi ball, and then evenly apply the ointment on the Bianstone ball around the navel, up to Zhongwan acupoint, down to Guanyuan acupoint, and left and right to cover Daheng acupoint. Massage Shenque, Zhongwan, Jianli, Tianshu, Guanyuan, Qihai, and Daheng acupoints in a clockwise direction.

[0043] The following are specific embodiments:

[0044] Example 1

[0045] A method for preparing an external Chinese medicinal ointment for treating functional constipation in the elderly comprises the following steps:

[0046] (1) Weigh the following ingredients by weight: 30 parts of Angelica sinensis, 20 parts of Achyranthes bidentata, 1 part of Sargentodoxae chinensis, 3 parts of Heishunpian, 2 parts of Citrus reticulata, 3 parts of Citrus aurantium, 1 part of Astragalus, 6 parts of Atractylodes macrocephala, 0.1 part of Carthamus tinctorius, 1 part of Semen persica, 4 parts of Notopterygium wilfordii, 2 parts of Rhubarb, 4 parts of Clove, 3 parts of Costusroot lappa, 2 parts of Asarum, and 3 parts of auxiliary materials.

[0047] The auxiliary material is prepared from Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora;

[0048] Among them, the mixed mass ratio of Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora is 18:15:12.

[0049] The preparation method of the auxiliary primer is as follows:

[0050] Firstly, Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora are mixed and crushed respectively, and then sieved through an 80-mesh sieve to obtain a mixed powder;

[0051] Take the mixed powder, add water 10 times the mass of the mixed powder, soak at room temperature for 40 minutes, then heat to boiling, keep it slightly boiling for 20 minutes over low heat, let it stand for 1 hour, filter it, remove the filter residue, and obtain the filtrate;

[0052] The filtrate is canned and sealed, and then placed in a high pressure steam sterilizer for steam sterilization at 121°C for 30 minutes, and then cooled to room temperature;

[0053] Add the lyophilized powder of fermentation bacteria to the cooled filtrate, stir and mix evenly, and then shake and ferment in a shaker at 37° C. and 200 r / min for 48 hours to obtain a fermentation liquid;

[0054] Then the fermentation liquid is concentrated to 10% of the original volume to obtain the auxiliary feed.

[0055] The mass ratio of the filtrate to the fermentation bacteria freeze-dried powder is 100:2.

[0056] Fermented bacteria freeze-dried powder: Each 100g of fermented bacteria freeze-dried powder contains 3.5×10 8 CFU and animal Bifidobacterium freeze-dried powder 2.4×10 8 CFU;

[0057] (2) Mixing: Add the above raw material components into a mixer and stir and mix for 20 minutes to obtain a uniform mixture;

[0058] Among them, the mixing and stirring speed is 200r / min;

[0059] (3) Crushing: adding the uniformly mixed material obtained above into a crusher for crushing, passing through a 60-mesh sieve to obtain a uniformly crushed material;

[0060] (4) decoction: add 15 times the mass of water to the uniformly pulverized material obtained above, heat to boiling, decoct over low heat for 4 hours, transfer to a vacuum impregnation reactor, vacuum impregnate for 2 hours, discharge, and obtain a decoction;

[0061] (5) Filtration and concentration:

[0062] The obtained decoction is filtered to remove the filter residue, and then concentrated to 10% of the original volume to obtain a concentrated paste, which is then filled, sealed, and sterilized.

[0063] The temperature of vacuum impregnation was 40°C and the vacuum degree was 0.1Pa.

[0064] The sterilization is steam sterilization; the steam sterilization time is 20 minutes and the temperature is 121°C.

[0065] Example 2

[0066] On the basis of Example 1, the difference from Example 1 is as follows: (1) the following parts by weight are weighed respectively: 35 parts of Angelica sinensis, 22 parts of Achyranthes bidentata, 2 parts of Sargentodoxae, 3.5 parts of Heishunpian, 3 parts of Citrus reticulata, 4 parts of Citrus aurantium, 2 parts of Astragalus, 8 parts of Atractylodes macrocephala, 0.2 parts of Carthamus tinctorius, 1.3 parts of Persica rapa, 5 parts of Notopterygium wilfordii, 2.5 parts of Rhubarb, 6 parts of Cloves, 5 parts of Costusroot lappa, 2.8 parts of Asarum, and 3.5 parts of auxiliary materials.

[0067] The auxiliary material is prepared from Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora;

[0068] Among them, the mixed mass ratio of Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora is 18:15:12.

[0069] The preparation method of the auxiliary primer is as follows:

[0070] Firstly, Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora are mixed and crushed respectively, and then sieved through an 80-mesh sieve to obtain a mixed powder;

[0071] Take the mixed powder, add water 10 times the mass of the mixed powder, soak at room temperature for 40 minutes, then heat to boiling, keep it slightly boiling for 20 minutes over low heat, let it stand for 1 hour, filter it, remove the filter residue, and obtain the filtrate;

[0072] The filtrate is canned and sealed, and then placed in a high pressure steam sterilizer for steam sterilization at 121°C for 30 minutes, and then cooled to room temperature;

[0073] Add the lyophilized powder of fermentation bacteria to the cooled filtrate, stir and mix evenly, and then shake and ferment in a shaker at 37° C. and 200 r / min for 48 hours to obtain a fermentation liquid;

[0074] Then the fermentation liquid is concentrated to 10% of the original volume to obtain the auxiliary feed.

[0075] The mass ratio of the filtrate to the fermentation bacteria freeze-dried powder is 100:2.5.

[0076] Fermented bacteria freeze-dried powder: Each 100g of fermented bacteria freeze-dried powder contains 3.5×10 8 CFU and animal Bifidobacterium freeze-dried powder 2.4×10 8 CFU.

[0077] Example 3

[0078] On the basis of Example 1, the difference from Example 1 is as follows: (1) the following parts by weight are weighed respectively: 40 parts of Angelica sinensis, 25 parts of Achyranthes bidentata, 3 parts of Sargentodoxae, 5 parts of Heishunpian, 4 parts of Citrus reticulata, 5 parts of Citrus aurantium, 3 parts of Astragalus, 9 parts of Atractylodes macrocephala, 0.3 parts of Carthamus tinctorius, 1.5 parts of Persica rapa, 7 parts of Notopterygium wilfordii, 3 parts of Rhubarb, 9 parts of Cloves, 6 parts of Costusroot lappa, 3 parts of Asarum, and 4 parts of auxiliary materials.

[0079] The auxiliary material is prepared from Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora;

[0080] Among them, the mixed mass ratio of Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora is 18:15:12.

[0081] The preparation method of the auxiliary primer is as follows:

[0082] Firstly, Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora are mixed and crushed respectively, and then sieved through an 80-mesh sieve to obtain a mixed powder;

[0083] Take the mixed powder, add water 10 times the mass of the mixed powder, soak at room temperature for 40 minutes, then heat to boiling, keep it slightly boiling for 20 minutes over low heat, let it stand for 1 hour, filter it, remove the filter residue, and obtain the filtrate;

[0084] The filtrate is canned and sealed, and then placed in a high pressure steam sterilizer for steam sterilization at 121°C for 30 minutes, and then cooled to room temperature;

[0085] Add the lyophilized powder of fermentation bacteria to the cooled filtrate, stir and mix evenly, and then shake and ferment in a shaker at 37° C. and 200 r / min for 48 hours to obtain a fermentation liquid;

[0086] Then the fermentation liquid is concentrated to 10% of the original volume to obtain the auxiliary feed.

[0087] The mass ratio of the filtrate to the fermentation bacteria freeze-dried powder is 100:3.

[0088] Fermented bacteria freeze-dried powder: Each 100g of fermented bacteria freeze-dried powder contains 3.5×10 8 CFU and animal Bifidobacterium freeze-dried powder 2.4×10 8 CFU.

[0089] Comparative Example 1: This comparative example is substantially the same as Example 2, except that no auxiliary initiator is added.

[0090] Comparative Example 2: This comparative example is substantially the same as Example 2, except that Magnolia officinalis is not added to the auxiliary material.

[0091] Comparative Example 3: This comparative example is basically the same as Example 2, except that no Gleditsia sinensis thorns are added to the auxiliary material.

[0092] Comparative Example 4: This comparative example is basically the same as Example 2, except that no herbaceous peony is added to the auxiliary material.

[0093] test:

[0094] 70 elderly patients with functional constipation, including 30 males and 40 females aged 55-65 years old, were randomly divided into 7 groups, with 10 people in each group. The samples of the embodiment and the comparative example were used for external application test, and the ointment was applied to the abdomen once a day for 4 consecutive weeks:

[0095] Efficacy criteria:

[0096] ① Clinical recovery means that after treatment, clinical symptoms completely disappear or basically disappear, and bowel movements return to normal;

[0097] ② Significantly effective means that after treatment, most of the clinical symptoms disappear and bowel movements basically return to normal;

[0098] ③ Effective means that after treatment, clinical symptoms improve, bowel movement intervals are significantly shortened, and stool becomes softer;

[0099] ④ Ineffective means that after treatment, the clinical symptoms do not improve or even worsen.

[0100] Total effective rate = [(clinical cure + number of markedly effective cases + number of effective cases) / total number of cases] × 100%;

[0101] Table 1

[0102]

[0103]

[0104] It can be seen from Table 1 that the Chinese medicinal ointment of the present invention has a higher therapeutic effect on functional constipation in the elderly.

[0105] The following constipation scoring criteria were used to score each group of the embodiment and the comparative example, and the average value was taken;

[0106] The score ranges from 0 to 4 points. Defecation time < 10 minutes is 0 points, 10 to 15 minutes (not including 15) is 1 point, 15 to 25 minutes is 2 points, and defecation time > 25 minutes is 3 points. The higher the score, the more severe the constipation symptoms.

[0107] Table 2

[0108]

[0109]

[0110] It can be seen from Table 2 that the use of the Chinese medicinal ointment prepared by the present invention can significantly shorten the defecation time.

[0111] PAC-QOL (Patient Self-Assessment Scale for Constipation) was used to evaluate the quality of life of patients in each group of the embodiment and the comparative example, including physical condition, dietary condition and mental state, and the average value was taken.

[0112] The score is recorded from 0 to 4, with no condition being 0, mild condition being 1, moderate condition being 2, severe condition being 3, and very severe condition being 4. The higher the score for each item, the worse the patient's quality of life:

[0113] Table 3

[0114] Quality of life score / points Example 1 0.3 Example 2 0.1 Example 3 0.4 Comparative Example 1 2.6 Comparative Example 2 1.3 Comparative Example 3 1.0 Comparative Example 4 1.2

[0115] As can be seen from Table 3, after treatment, the patient's quality of life has been significantly improved.

[0116] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A Chinese medicinal ointment for external use for treating functional constipation in the elderly, characterized in that: By weight Includes the following ingredients: 30-40 parts of angelica sinensis, 20-25 parts of Achyranthes bidentata, 1-3 parts of Sargentodoxa chinensis, 3-5 parts of Heishunpian, 2-4 parts of dried tangerine peel, 3-5 parts of immature bitter orange, 1-3 parts of astragalus, 6-9 parts of atractylodes macrocephala, 0.1-0.3 parts of safflower, 1-1.5 parts of peach kernel, 4-7 parts of notopterygium wilfordii, 2-3 parts of rhubarb, 4-9 parts of cloves, 3-6 parts of costusroot, 2-3 parts of asarum, and 3-4 parts of auxiliary materials.

2. The external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 1, characterized in that: The auxiliary material is prepared from Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora; Among them, the mixed mass ratio of Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora is 18:15:

12.

3. The external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 2, characterized in that: The auxiliary material preparation method is: Firstly, Magnolia officinalis, Gleditsia sinensis and Paeonia lactiflora are mixed and crushed respectively, and then sieved through an 80-mesh sieve to obtain a mixed powder; Take the mixed powder, add water 10 times the mass of the mixed powder, soak at room temperature for 40 minutes, then heat to boiling, keep it slightly boiling for 20 minutes over low heat, let it stand for 1 hour, filter it, remove the filter residue, and obtain the filtrate; The filtrate is canned and sealed, and then placed in a high pressure steam sterilizer for steam sterilization at 121°C for 30 minutes, and then cooled to room temperature; Add the lyophilized powder of fermentation bacteria to the cooled filtrate, stir and mix evenly, and then shake and ferment in a shaker at 37° C. and 200 r / min for 48 hours to obtain a fermentation liquid; Then the fermentation liquid is concentrated to 10% of the original volume to obtain the auxiliary feed.

4. The external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 3, characterized in that: The mass ratio of the filtrate to the fermentation bacteria freeze-dried powder is 100:2-3.

5. The external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 4, characterized in that: The fermented bacteria freeze-dried powder contains 3.5×10 Lactobacillus acidophilus freeze-dried powder per 100g of the fermented bacteria freeze-dried powder. 8 CFU and animal Bifidobacterium freeze-dried powder 2.4×10 8 CFU.

6. The method for preparing an external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 1, characterized in that: The following steps are involved: (1) Weigh the following ingredients by weight: Chinese Angelica, Achyranthes bidentata, Sargentodoxae, Heishun Pian, Tangerine Peel, Citrus Aurantium, Astragalus, Atractylodes, Carthamus tinctorius, Semen persicae, Notopterygium wilfordii, Rhubarb, Clove, Aucklandia lappa, Asarum, and auxiliary materials; (2) Mixing: Add the above raw material components into a mixer and stir and mix for 20 minutes to obtain a uniform mixture; Among them, the mixing and stirring speed is 200r / min; (3) Crushing: adding the uniformly mixed material obtained above into a crusher for crushing, passing through a 60-mesh sieve to obtain a uniformly crushed material; (4) decoction: add 15 times the mass of water to the uniformly pulverized material obtained above, heat to boiling, decoct over low heat for 4 hours, transfer to a vacuum impregnation reactor, vacuum impregnate for 2 hours, discharge, and obtain a decoction; (5) Filtration and concentration: The obtained decoction is filtered to remove the filter residue, and then concentrated to 10% of the original volume to obtain a concentrated paste, which is then filled, sealed, and sterilized.

7. The method for preparing an external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 6, characterized in that: The temperature of the vacuum impregnation is 40° C. and the vacuum degree is 0.1 Pa.

8. The method for preparing an external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 6, characterized in that: The sterilization is steam sterilization.

9. The method for preparing an external Chinese medicinal ointment for treating functional constipation in the elderly according to claim 8, characterized in that: The steam sterilization time is 20 minutes and the temperature is 121°C.

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