Carbon quantum dot with whitening function and preparation method and application thereof

Abstract

The invention belongs to the technical field of daily chemical industry, and discloses a carbon quantum dot with a whitening function and a preparation method and application thereof. The preparation method comprises the following steps: uniformly mixing a carbon-containing whitening component, a nitrogen source and water, carrying out hydrothermal reaction, cooling, filtering and dialyzing to obtain the carbon quantum dots with the whitening function. The carbon quantum dots are subjected to high-temperature treatment in the synthesis process, the obtained product has thermal stability and light stability, the problem that traditional whitening components are unstable is solved, and the application scene of whitening cosmetics under the illumination condition is expanded. The quantum dot not only retains the whitening disclosure of a carbon-containing whitening component, but also has the function of absorbing ultraviolet rays, can reduce the generation of skin melanin from two pathways of physically shielding ultraviolet rays and chemically inhibiting tyrosinase activity, and has dual effects; compared with common carbon quantum dots and whitening components which only have a single whitening pathway, melanin generation is more efficiently inhibited. Therefore, the carbon quantum dots can be used for preparing whitening skin care products.

Description

Technical Field

[0001] The invention belongs to the technical field of daily chemical industry, and particularly relates to carbon quantum dots with whitening function and a preparation method and application thereof. Background Art

[0002] Ultraviolet (UV) rays are part of solar radiation and have a dual impact on human health. A moderate amount of UV rays helps the body synthesize vitamin D, but excessive UV rays can cause multiple hazards to the human body. For example, UV rays can cause skin aging and skin cancer. They can penetrate the surface of the skin, cause DNA damage, and increase the risk of skin cancer. Therefore, it is of great significance to develop UV-absorbing skin care products with a wide UV absorption spectrum and good stability.

[0003] Whitening agents are a type of active ingredient used in whitening cosmetics that helps reduce or slow down skin pigmentation and achieve skin whitening and brightening effects. Commonly used whitening agents include but are not limited to arbutin, niacinamide, glabridin, phenylethyl resorcinol, ascorbic acid (vitamin C), ascorbyl glucoside, 3-o-ethyl ascorbic acid, etc. These whitening agents achieve whitening effects through different mechanisms, such as inhibiting the production of melanin, blocking the transport of melanin, reducing melanin, or promoting the shedding of epidermal melanin. However, some whitening agents may be photosensitizing, and use in the sun may cause skin allergies or irritation, which also limits the application scenarios of whitening agents. In order to ensure the safety and effectiveness of whitening products, countries and regions have set restrictions on the use of whitening agents. For example, the EU has re-evaluated the safety of arbutin and stipulated that the maximum safe concentration of α-arbutin in face creams is 2%, the maximum safe concentration in body lotions is 0.5%, and the maximum safe concentration of β-arbutin in face creams is 7%, because arbutin may degrade under light conditions to produce hydroquinone, which is a toxic substance and has been listed as a prohibited raw material for cosmetics in many countries. Therefore, it is of great significance to develop a whitening ingredient with good light stability and high safety. Summary of the invention

[0004] The primary purpose of the present invention is to overcome the shortcomings and deficiencies of the prior art and provide a method for preparing carbon quantum dots with whitening function.

[0005] Another object of the present invention is to provide carbon quantum dots with whitening function obtained by the above preparation method.

[0006] Another object of the present invention is to provide an application of the above-mentioned carbon quantum dots with whitening function.

[0007] The purpose of the present invention is achieved by the following technical solution: A method for preparing carbon quantum dots with whitening function, comprising the following steps:

[0008] (1) mixing the carbon-containing whitening component, the nitrogen source and water uniformly, followed by hydrothermal reaction;

[0009] (2) Cooling the product of the reaction in step (1) and filtering it, followed by dialysis to remove unreacted small molecules, thereby obtaining carbon quantum dots with whitening function.

[0010] The above preparation method also includes the following steps: (3) drying to obtain carbon quantum dots with whitening function that are easy to store.

[0011] The carbon-containing whitening ingredient in step (1) is preferably a carbon-containing whitening ingredient; more preferably at least one of quercetin, glabridin, phenethyl resorcinol, α-arbutin and β-arbutin.

[0012] The nitrogen source described in step (1) is preferably a water-soluble nitrogen source; more preferably at least one of nicotinamide and ethylenediamine.

[0013] The carbon-containing whitening component and the nitrogen source in step (1) are preferably mixed in a mass ratio of 2 to 5:1; more preferably in a mass ratio of 4.5:1.

[0014] The water in step (1) is preferably distilled water, which does not participate in the reaction, but serves as a medium to facilitate uniform mixing of the carbon-containing whitening component and the nitrogen source, and the hydrothermal reaction.

[0015] The mixing method in step (1) is preferably ultrasound.

[0016] The mixing time in step (1) is preferably 5 to 10 minutes.

[0017] The conditions of the hydrothermal reaction in step (1) are preferably: temperature 160-200° C., time 4-8 h; more preferably: temperature 170-190° C., time 5-7 h; most preferably: temperature 180° C., time 6 h.

[0018] The filtration in step (2) is preferably carried out using a 0.22 μm filter membrane.

[0019] The specification of the dialysis bag in the dialysis described in step (2) is preferably 500-1000Da.

[0020] The dialysis time in step (2) is preferably 12 to 36 hours, more preferably 24 hours.

[0021] A carbon quantum dot with whitening function is obtained by the above preparation method.

[0022] The application of the above carbon quantum dots with whitening function in the preparation of whitening skin care products.

[0023] A whitening skin care product contains the carbon quantum dots with whitening function.

[0024] The content of the carbon quantum dots with whitening function in the whitening skin care product is preferably 0.01% to 0.2% by mass; preferably 0.1% to 0.2% by mass.

[0025] The dosage form of the whitening skin care product is preferably essence, lotion, cream, gel or mask.

[0026] A whitening and anti-ultraviolet carbon quantum dot essence contains the following components by mass percentage: 1-5% glycerol, 1-3% 1,3-butylene glycol, 1-4% glycerol polyether-26, 1-5% purslane extract, 1-5% mushroom glucan, and 0.1-50% carbon quantum dots with whitening function.

[0027] The whitening and anti-ultraviolet carbon quantum dot essence also contains water, or contains at least one of a pigment, an essence and a preservative and water.

[0028] The water content is the balance.

[0029] The content of the carbon quantum dots with whitening function is preferably 0.1 to 25%, and more preferably 0.1 to 12.5%.

[0030] A sunscreen with whitening effect contains the following components by mass percentage: 0.1-50% of carbon quantum dots with whitening function, 2-4% of octadecyl alcohol, 1-3% of beeswax, 1-3% of silicone oil, 2-5% of monoglyceride of fatty acid, 2-5% of stearyl alcohol polyether-21, 1-4% of glycerol polyether-26, 1-5% of mushroom glucan, 2-5% of glycerol, 1-3% of 1,3-butylene glycol, and 0.5-1% of carbomer 940.

[0031] The sunscreen with whitening effect also contains water, or contains at least one of a pigment, an essence and a preservative and water.

[0032] The water content is the balance.

[0033] The content of the carbon quantum dots with whitening function is preferably 0.1 to 25%, and more preferably 0.1 to 12.5%.

[0034] The principle of the present invention is:

[0035] The carbon quantum dots synthesized by using raw materials with whitening effects as precursor substances can retain some of the active groups of the precursor substances, such as resorcinol groups, phenolic hydroxyl groups, etc., which can specifically bind to tyrosinase in melanocytes, competitively reduce the binding of tyrosine to tyrosinase, block the process of melanin formation, and make the carbon quantum dots have certain whitening functions. At the same time, during the synthesis process of carbon quantum dots, they have been treated with high temperature and high pressure, and the obtained products have thermal stability and light stability, which overcomes the problem of instability of traditional whitening ingredients and expands its application scenarios under light conditions. In addition, as a new type of nanomaterial with good optical properties, carbon quantum dots can change the band structure and electronic transition characteristics of carbon quantum dots by doping nitrogen atoms, thereby enhancing their ultraviolet absorption capacity. Carbon quantum dots inherit the low toxicity, good biocompatibility and easy degradation of carbon materials, meet the basic requirements of cosmetic raw materials, and can be added to lotions and essences to make skin care products with whitening and anti-ultraviolet effects.

[0036] Compared with the prior art, the present invention has the following advantages and effects:

[0037] (1) The present invention prepares carbon quantum dots with whitening effect for the first time, using substances with tyrosinase inhibitory activity as precursors, providing carbon quantum dots with functional groups that can specifically bind to tyrosinase, and can target and inhibit the formation of melanin catalyzed by tyrosinase.

[0038] (2) The carbon quantum dots of the present invention also have the function of absorbing ultraviolet rays. They can reduce the production of melanin in the skin through two pathways: physically shielding ultraviolet rays and chemically inhibiting the activity of tyrosinase. They have a dual effect and are more efficient in inhibiting melanin production than ordinary carbon quantum dots and whitening ingredients that only have a single whitening pathway.

[0039] (3) The carbon quantum dots of the present invention are treated with high temperature and high pressure during the synthesis process, and the obtained product has thermal stability and light stability, which overcomes the problem of instability of traditional whitening ingredients and expands the application scenarios of whitening cosmetics under light conditions.

[0040] (4) Colorless and odorless nicotinamide is used as the intra-ring nitrogen dopant, which overcomes the problem of existing commonly used dopants such as N,N-dimethylformamide and o-phenylenediamine having a bad odor and being highly irritating to human skin and nasal mucosa. The production process is safe, green and environmentally friendly. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] Figure 1 These are photographs of the carbon quantum dot aqueous solution prepared in Example 1 under different light irradiations; wherein a) is visible light irradiation, and b) is ultraviolet light irradiation.

[0042] Figure 2This is a graph showing the transmittance and absorbance curves of the carbon quantum dots prepared in Example 1.

[0043] Figure 3 These are photos of zebrafish from different groups; the left column of each group is a top-down photo, and the right column is a side-on photo.

[0044] Figure 4 This is a graph showing the stability test results of the carbon quantum dots prepared in Example 1.

[0045] Figure 5 This is a graph showing the stability test results of the carbon quantum dots prepared in Example 2. DETAILED DESCRIPTION

[0046] The present invention is further described in detail below in conjunction with embodiments and drawings, but the embodiments of the present invention are not limited thereto.

[0047] Unless otherwise specified, the reagents used in the examples can be purchased from the market.

[0048] Example 1

[0049] (1) A method for preparing water-soluble whitening and anti-ultraviolet carbon quantum dots, the specific steps are as follows:

[0050] Weigh 500mg α-arbutin and 125μL ethylenediamine and dissolve them in 50mL distilled water. Ultrasonicate them in an ultrasonic water bath for 5min, then transfer them to the polyvinyl fluoride lining of the hydrothermal reactor. Then tighten the hydrothermal reactor and place it in a vacuum drying oven at 180℃ for 6h. After cooling, take out the reaction solution, filter the macromolecular impurities with a 0.22μm filter membrane, and dialyze with a 500Da dialysis bag for 24h to remove the small molecular substances that have not reacted completely. The residual liquid obtained is a carbon quantum dot solution, which is bright yellow under visible light. Figure 1 As shown in a); under ultraviolet light, the color is yellow-green, such as Figure 1 The brown solid carbon quantum dots can be obtained by freeze-drying the carbon quantum dot solution for 48 hours, which can be sealed and stored in a desiccator. When used, the carbon quantum dot solution of corresponding concentration can be prepared for standby use. The yield of carbon quantum dots is 25.56%.

[0051] Pour the carbon quantum dot solution into a cuvette, set a suitable wavelength range (200-900nm) on the UV-visible spectrophotometer, scan from high wavelength to low wavelength, and record the UV-visible absorption spectrum and transmittance of the carbon quantum dots. Figure 2 It can be seen that the carbon quantum dots can absorb wavelengths in the UVA and UVB bands, effectively reduce the transmission of ultraviolet rays, and the transmittance of visible light is more than 80%, making it an ideal anti-ultraviolet agent.

[0052] (2) Zebrafish whitening experiment

[0053] ① Wild-type AB strain zebrafish were used, and male and female zebrafish were separated and cultured in two fish tanks, with 14 hours of light and 10 hours of darkness. The night before the experiment, the male and female fish were scooped into the breeding tank in a male-to-female ratio of 2:1, and the male and female were separated by a partition. The partition was removed at 9 o'clock the next morning, and the light was turned on to stimulate mating and spawning. At 3 o'clock in the afternoon, zebrafish embryos that developed normally 6 hours after fertilization were collected in a 6-well plate, with 15 embryos per well, and 2 replicate wells were set for each concentration.

[0054] ② Preparation of zebrafish embryo culture medium: NaHCO3 2.5901g, KCl 0.2305g, CaCl2·2H2O11.7603g, MgSO4·7H2O 4.9304g. Dissolve the above reagents with ultrapure water and make up to 1L.

[0055] ③ Determination of zebrafish melanin: Dissolve the carbon quantum dots in distilled water to 1000μg / mL, 500μg / mL, and 100μg / mL, respectively. Take 3mL of the above solution and add it to a 6-well plate, place it in a biochemical incubator at 28℃ for 72h, observe the embryonic development every day, pick out the dead embryos in time and keep records, and count the hatching rate, mortality rate and deformity rate of the embryos after 72 hours to evaluate the toxicity of carbon quantum dots to zebrafish embryos, and the gray value of melanin in hatched zebrafish fry to count the inhibition rate of carbon quantum dots on zebrafish melanin production. At the same time, set up a control group and a blank control group. The blank control group is a group in which the zebrafish embryos are not added with the test samples, and the control group is a group in which the test samples are 1000μg / mL, 500μg / mL, and 100μg / mL α-arbutin.

[0056] (3) Determination of the stability of carbon quantum dots:

[0057] UV stability test: The carbon quantum dot solution was placed 20 cm away from a 10 W UV lamp (365 nm) for 24 h to obtain carbon quantum dots I.

[0058] Storage stability test: The carbon quantum dot solution was stored at 28°C in the dark for 14 days to obtain carbon quantum dots II.

[0059] Carbon quantum dots I, carbon quantum dots II and carbon quantum dots solution without stability test were used in zebrafish whitening experiment to determine the changes in the ability of carbon quantum dots to inhibit melanin production in zebrafish before and after treatment.

[0060] (4) Results

[0061] From Table 1 and Figure 3It can be seen that the carbon quantum dots that have not been treated with stability tests have no significant difference in the hatching rate and mortality rate of zebrafish embryos compared with the blank control group, and the carbon quantum dots will not be toxic to zebrafish embryos. Figure 4 It can be seen that the whitening effect of carbon quantum dots increases significantly with the increase of the concentration of carbon quantum dots. At a concentration of 1000 μg / mL, the whitening effect of carbon quantum dots is better than that of its precursor α-arbutin. After the carbon quantum dot solution was treated with ultraviolet light and stored for 14 days, there was no significant change in the inhibition rate of zebrafish melanin production, and the prepared carbon quantum dots had good ultraviolet stability and storage stability. It can be concluded that the carbon quantum dots prepared by the present invention have low toxicity and good whitening effect, which improves the safety and practicality of the application.

[0062] Table 1 Effects of nitrogen-doped α-arbutin carbon quantum dots on zebrafish larvae

[0063]

[0064] Example 2

[0065] (1) A method for preparing whitening and anti-ultraviolet carbon quantum dots, the specific steps are as follows:

[0066] Weigh 500 mg of arbutin and 250 mg of nicotinamide and dissolve them in 50 mL of distilled water. Ultrasonicate them in an ultrasonic water bath for 5 minutes, then transfer them to the polyfluoroethylene liner of the hydrothermal reactor, and then tighten the hydrothermal reactor and place it in a vacuum drying oven for 6 hours at 180 ° C. After cooling, take out the reaction solution, filter the macromolecular impurities with a 0.22 μm filter membrane, and dialyze with a 500 Da dialysis bag for 24 hours to remove the small molecular substances that have not reacted completely. The retentate is freeze-dried to obtain a yellow-brown powder. The yield of carbon quantum dots is 28.73%.

[0067] (2) Zebrafish whitening experiment

[0068] ① Wild-type AB strain zebrafish were used, and male and female zebrafish were separated and cultured in two fish tanks, with 14 hours of light and 10 hours of darkness. The night before the experiment, the male and female fish were scooped into the breeding tank in a male-to-female ratio of 2:1, and the male and female were separated by a partition. The partition was removed at 9 o'clock the next morning, and the light was turned on to stimulate mating and spawning. At 3 o'clock in the afternoon, zebrafish embryos that developed normally 6 hours after fertilization were collected in a 6-well plate, with 15 embryos per well, and 2 replicate wells were set for each concentration.

[0069] ② Preparation of zebrafish embryo culture medium: NaHCO3 2.5901g, KCl 0.2305g, CaCl2·2H2O11.7603g, MgSO4·7H2O 4.9304g. Add ultrapure water to make up to 1L.

[0070] ③ Determination of zebrafish melanin: Dissolve the carbon quantum dots in deionized water to 500μg / mL, 250μg / mL, and 125μg / mL, respectively. Take 3mL of the above solution and add it to a 6-well plate, place it in a biochemical incubator at 28℃ for 72h, observe the embryonic development every day, pick out the dead embryos in time and keep records. After 72 hours, the hatching rate, mortality rate and deformity rate of the embryos were calculated to evaluate the toxicity of carbon quantum dots to zebrafish embryos, and the gray value of melanin in the hatched zebrafish fry was used to calculate the inhibition rate of carbon quantum dots on zebrafish melanin production. A mixture of arbutin and nicotinamide with a corresponding concentration ratio of 2:1 was used as the control group.

[0071] (3) Determination of the stability of carbon quantum dots:

[0072] UV stability test: The carbon quantum dot solution was placed 20 cm away from a 10 W UV lamp (365 nm) for 24 h to obtain carbon quantum dots I.

[0073] Storage stability test: The carbon quantum dot solution was stored at 28°C in the dark for 14 days to obtain carbon quantum dots II.

[0074] Carbon quantum dots I, carbon quantum dots II and carbon quantum dots solution without stability test were used in zebrafish whitening experiment to determine the changes in the ability of carbon quantum dots to inhibit melanin production in zebrafish before and after treatment.

[0075] (4) Results

[0076] As shown in Table 2, there is no significant difference between the hatching rate and mortality rate of zebrafish embryos treated with carbon quantum dots and the blank control group, and carbon quantum dots are not toxic to zebrafish embryos. Figure 5 It can be seen that the whitening effect of carbon quantum dots is significantly improved with the increase of the concentration of carbon quantum dots. The whitening effect of carbon quantum dots is better than that of its precursor mixture. The effective whitening concentration of carbon quantum dots prepared by this scheme is much lower than that of the carbon quantum dots prepared in Example 1. The carbon dot solution has no significant change in the inhibition rate of zebrafish melanin production after ultraviolet irradiation treatment and storage for 14 days. The prepared carbon quantum dots have good ultraviolet stability and storage stability. It can be concluded that the carbon quantum dots prepared in this embodiment have low toxicity and good whitening effect, which improves the safety, practicality and stability of application.

[0077] Table 2 Effects of carbon quantum dots on zebrafish larvae

[0078]

[0079] Example 3

[0080] The invention provides a whitening and anti-ultraviolet carbon quantum dot essence. The raw material composition of the essence is as follows by mass percentage: 1-5% of glycerol, 1-3% of 1,3-butylene glycol, 1-4% of glycerol polyether-26, 1-5% of purslane extract, 1-5% of mushroom glucan, 0.1-50% of the whitening and anti-ultraviolet carbon quantum dots prepared in Example 1, and the balance of deionized water.

[0081] The carbon quantum dots prepared by the present invention not only retain the whitening performance of α-arbutin, but also retain the ultraviolet absorption performance of the carbon quantum dots, and are very suitable for being added as an effective ingredient in facial cosmetics.

[0082] The whitening and anti-ultraviolet carbon quantum dot essence can be prepared by the following preparation method, and the operation steps are as follows:

[0083] S1: Weigh glycerol, 1,3-butylene glycol and glycerol polyether-26 in beaker No. 1 and stir evenly;

[0084] S2: Add the whitening and anti-ultraviolet carbon quantum dots prepared in Example 1, purslane extract, mushroom glucan and deionized water, and stir evenly at 700-1000 rpm to obtain a whitening and anti-ultraviolet carbon quantum dot essence.

[0085] The application effect of the present invention is as follows: the essence is a clear and transparent aqueous system, and the essence contains whitening and anti-ultraviolet carbon quantum dots, which can effectively inhibit the formation of melanin and have the effect of resisting ultraviolet radiation; the addition of glycerol polyether-26, purslane extract and mushroom glucan provides the skin with multifunctional anti-inflammatory, anti-aging, after-sun repair and whitening active ingredients, which can effectively lock moisture, reduce water loss, increase skin water content and firmness, and promote cell growth, wound healing and enhance immunity; the addition of glycerol and 1,3-butylene glycol can be used as a good moisturizer, which can improve a strong moisturizing barrier during use, making it easier for other active ingredients to be absorbed by the skin.

[0086] Example 4

[0087] The invention provides a sunscreen with whitening effect. The raw material composition of the sunscreen is as follows by mass percentage: 0.1-12.5% ​​of whitening and anti-ultraviolet carbon quantum dots prepared in Example 2, 2-4% of octadecyl alcohol, 1-3% of beeswax, 1-3% of silicone oil, 2-5% of monoglyceride of fatty acid, 2-5% of stearyl alcohol polyether 21, 1-4% of glycerol polyether-26, 1-5% of mushroom glucan, 2-5% of glycerol, 1-3% of 1,3-butylene glycol, 0.5-1% of carbomer 940, and the balance of deionized water.

[0088] The whitening and anti-ultraviolet carbon quantum dots prepared by the present invention not only retain the whitening performance of arbutin, but also retain the ultraviolet absorption performance of the carbon quantum dots, thus overcoming the problem of limited use of arbutin in a sunlight environment, and are suitable for being added as an effective ingredient in sunscreen.

[0089] The sunscreen with whitening effect can be prepared by the following preparation method, and the operation steps are as follows:

[0090] S1: Weigh octadecyl alcohol, beeswax, silicone oil, monoglyceride, and steareth-21 in a No. 1 beaker and stir evenly;

[0091] S2: Add whitening and anti-ultraviolet carbon quantum dots, glycerol, 1,3-butylene glycol, glycerol polyether-26, carbomer 940, and mushroom glucan into beaker No. 2, dissolve the oil phase and water phase components at a certain temperature (85°C), prepare a lipophilic and hydrophilic mixture, and mix it evenly through a homogenizer (temperature 60-80°C, pressure 100-200 bar, speed 3000-5000 rpm, time 3-20 min); then add an appropriate amount of pH stabilizer triethanolamine to adjust the pH value to 5.2-5.7, and the sunscreen is prepared.

[0092] The application effect of the present invention is as follows: the sunscreen is a light yellow lipophilic and hydrophilic mixture, and the whitening and anti-ultraviolet carbon quantum dots contained in the sunscreen can effectively inhibit the generation of melanin and have the effect of resisting ultraviolet radiation. The addition of glycerol polyether-26 and mushroom glucan provides the skin with multifunctional anti-inflammatory, anti-aging, after-sun repair and whitening active ingredients, which can effectively lock moisture, reduce water loss, increase skin moisture content and firmness, and promote cell growth, wound healing and enhance immunity. The addition of glycerol and 1,3-butylene glycol can be used as a good moisturizer, which can improve a strong moisturizing barrier during use, making it easier for other active ingredients to be absorbed by the skin.

[0093] The above are only embodiments of the present invention, but those skilled in the art should understand that the embodiments herein can be modified without departing from the spirit of the present invention. Of course, this cannot be used to limit the scope of the rights of the present invention, so equivalent changes made according to the claims of the present invention are still within the scope of the present invention.

Claims

1. A method for preparing carbon quantum dots with whitening function, characterized in that The steps include: (1) mixing the carbon-containing whitening component, the nitrogen source and water uniformly, followed by hydrothermal reaction; (2) cooling the product of the reaction in step (1) and filtering it, and then dialyzing to remove unreacted small molecules to obtain carbon quantum dots with whitening function; Or include the following steps: (1) mixing the carbon-containing whitening component, the nitrogen source and water uniformly, followed by hydrothermal reaction; (2) cooling the product of step (1) and filtering it, followed by dialysis to remove unreacted small molecules; (3) Drying to obtain carbon quantum dots with whitening function that are easy to store.

2. The method for preparing carbon quantum dots with whitening function according to claim 1, characterized in that: The carbon-containing whitening ingredient in step (1) is a water-soluble carbon-containing whitening ingredient; The nitrogen source described in step (1) is a water-soluble nitrogen source.

3. The method for preparing carbon quantum dots with whitening function according to claim 2, characterized in that: The carbon-containing whitening ingredient is at least one of quercetin, glabridin, phenethyl resorcinol, α-arbutin and β-arbutin; The nitrogen source is at least one of nicotinamide and ethylenediamine.

4. The method for preparing carbon quantum dots with whitening function according to claim 1, characterized in that: The carbon-containing whitening component and the nitrogen source in step (1) are mixed in a mass ratio of 2 to 5:

1.

5. The method for preparing carbon quantum dots with whitening function according to claim 1, characterized in that: The conditions of the hydrothermal reaction in step (1) are: temperature 160-200° C., time 4-8 h; The filtration in step (2) is performed using a 0.22 μm filter membrane; The specification of the dialysis bag in the dialysis described in step (2) is 500-1000Da.

6. A carbon quantum dot with whitening function, characterized in that: The method is obtained by the preparation method according to any one of claims 1 to 5.

7. Use of the carbon quantum dots with whitening function as claimed in claim 6 in the preparation of whitening skin care products.

8. A whitening skin care product, characterized in that: Contains the carbon quantum dots with whitening function as claimed in claim 6.

9. A whitening and anti-ultraviolet carbon quantum dot essence, characterized in that The invention contains the following components by mass percentage: 0.1-50% carbon quantum dots with whitening function, 1-5% glycerol, 1-3% 1,3-butylene glycol, 1-4% glycerol polyether-26, 1-5% purslane extract and 1-5% mushroom glucan.

10. A sunscreen with whitening effect, characterized in that The invention contains the following components by mass percentage: 0.1-50% carbon quantum dots with whitening function, 2-4% octadecyl alcohol, 1-3% beeswax, 1-3% silicone oil, 2-5% monoglyceride of fatty acid, 2-5% stearyl alcohol polyether-21, 1-4% glyceryl polyether-26, 1-5% mushroom glucan, 2-5% glycerol, 1-3% 1,3-butylene glycol, and 0.5-1% carbomer 940.

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