Water-soluble polysiloxane, method for producing the same, and use thereof

Abstract

The application belongs to the field of high polymer chemistry, and particularly relates to a water-soluble polysiloxane, a preparation method and application thereof. The water-soluble polysiloxane has a structure as shown in formula I: wherein R1 is aminoethyl aminopropyl, R2 is vinyl or phenyl, X+Y=100%, X=35%-100% and 100% is excluded. The water-soluble polysiloxane has hydrophilicity and adjustable solubility, and the solubility in water can be regulated by adjusting the proportion of various groups in the formula, and can be widely applied to the fields of coating, cosmetics, medicine and the like.

Description

Technical Field

[0001] This invention belongs to the field of polymer chemistry, specifically relating to a water-soluble polysiloxane, its preparation method, and its applications. Background Technology

[0002] The information disclosed in this background section is intended only to enhance understanding of the overall background of the invention and is not necessarily to be construed as an admission or in any way implying that such information constitutes prior art known to those skilled in the art.

[0003] Polysiloxanes are widely used in various fields due to their excellent chemical stability, thermal stability, and biocompatibility. Traditional polysiloxane materials are predominantly hydrophobic, which limits their application in some situations requiring hydrophilic properties. To prepare hydrophilic polysiloxane materials, one approach is to copolymerize hydrophilic monomers with siloxane monomers; however, siloxane monomers generally have poor compatibility with hydrophilic monomers due to their high hydrophobicity. Another approach is to prepare polysiloxanes containing hydrophilic side chains by introducing hydrophilic groups such as amino and hydroxyl groups into the polysiloxane structure, thus producing polysiloxane materials with good water solubility. However, existing polysiloxanes contain a variety of hydrophilic side chains in each molecule, making it difficult to control the hydrophilicity and solubility. Summary of the Invention

[0004] To address the shortcomings of existing technologies, this invention provides a water-soluble polysiloxane, its preparation method, and its applications. The water-soluble polysiloxane is hydrophilic and has adjustable solubility. Its solubility in water can be controlled by adjusting the proportion of various functional groups in the formulation. It can be widely used in coatings, cosmetics, pharmaceuticals, and other fields.

[0005] To achieve the above objectives, the present invention is implemented through the following technical solution:

[0006] In a first aspect, the present invention provides a water-soluble polysiloxane having a structure as shown in Formula I:

[0007]

[0008] Wherein, R1 is aminoethylaminopropyl, R2 is vinyl or phenyl, X+Y = 100%, and X = 35%-100% excluding 100%.

[0009] Preferably, when R2 is vinyl, X = 50%-100%, but not including 100%.

[0010] More preferably, when R2 is vinyl, X = 70%-95%.

[0011] Preferably, when R2 is phenyl, X = 70%-100%, excluding 100%.

[0012] More preferably, when R2 is phenyl, X = 80%-95%.

[0013] In a second aspect, the present invention provides a method for preparing water-soluble polysiloxane as described in the first aspect, comprising the following steps:

[0014] The water-soluble polysiloxane is obtained by mixing silane, aminoethylaminopropylsilane, catalyst and deionized water, reacting under an inert atmosphere, and then distilling under reduced pressure.

[0015] Preferably, the silane comprises at least one of tetramethyltetravinylcyclotetrasiloxane, dimethoxymethylvinylsilane, methylvinyldiethoxysilane, methylbis(trimethylsiloxy)vinylsilane, methylphenylcyclosiloxane, dimethoxymethylphenylsilane, and diethoxymethylphenylsilane.

[0016] Preferably, the aminoethylaminopropylsilane includes at least one of N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane and N-(β-aminoethyl-γ-aminopropyl)methyldiethoxysilane.

[0017] Preferably, the catalyst comprises at least one of tetramethylammonium hydroxide (TMHA), tetramethylammonium hydroxide silanoate, sodium hydroxide, and potassium hydroxide.

[0018] Preferably, the reaction temperature is 40℃~200℃ and the reaction time is 0.5~10h.

[0019] Preferably, the reaction is carried out in two steps: first, the reaction is carried out at 90℃~110℃ for 0.5~3h, and then the temperature is raised to 140℃~160℃ for 0.5~1h.

[0020] Thirdly, the present invention provides the application of water-soluble polysiloxanes as described in the first aspect in the fields of water-based coatings, cosmetics, drug carriers, or environmental protection.

[0021] The beneficial effects achieved by one or more technical solutions of the present invention are as follows:

[0022] Water-soluble polysiloxanes can effectively regulate their solubility in water by adjusting the proportion of hydrophilic groups, thus meeting the needs of different application scenarios.

[0023] The synthesis method of water-soluble polysiloxanes is simple to operate, can achieve efficient synthesis under relatively mild conditions, and has good operability.

[0024] Water-soluble polysiloxanes can be widely used in water-based coatings, cosmetics, drug carriers and other fields, and have great potential, especially in the fields of environmental protection and biomedicine. Attached Figure Description

[0025] The accompanying drawings, which form part of this invention, are used to provide a further understanding of the invention. The illustrative embodiments of the invention and their descriptions are used to explain the invention and do not constitute an improper limitation of the invention.

[0026] Figure 1 Schematic diagrams of the molecular structures of (a) VAPSi and (b) PhAPSi;

[0027] Figure 2 For (a)VAPSi 1-9 and (b)PhAPSi 3-7 The infrared (FT-IR) spectrum;

[0028] Figure 3 For (a)VAPSi 1-9 and (b)PhAPSi 3-7 The hydrogen nuclear magnetic (¹H NMR) spectrum. Detailed Implementation

[0029] To enable those skilled in the art to better understand the technical solution of the present invention, the technical solution of the present invention will be described in detail below with reference to specific embodiments and comparative examples.

[0030] The unit containing R1 is named the methylaminoethylaminopropyl unit. When R2 is vinyl, the water-soluble polysiloxane is named VAPSi, and the unit containing R2 is named the methylvinyl unit. A schematic diagram of the VAPSi molecular structure is shown below. Figure 1 As shown in (a); when R2 is phenyl, the water-soluble polysiloxane is named PhAPSi, and the repeating unit containing R2 is named methylphenyl repeating unit. The schematic diagram of the PhAPSi molecular structure is shown in Figure 1. Figure 1 As shown in (b) of the diagram.

[0031] The solubility determination scheme for water-soluble polysiloxanes is as follows:

[0032] A certain mass of water-soluble polysiloxane sample was added to a known volume of deionized water. The mixture was placed in a temperature-controlled water bath at 25°C and stirred continuously for 1–24 hours to ensure sufficient contact between the water-soluble polysiloxane and the water. During the dissolution process, samples were periodically taken and filtered to remove undissolved portions until no further dissolution occurred. The filtered solution was evaporated to obtain the mass of dissolved polysiloxane, and the solubility of the water-soluble polysiloxane was calculated using a formula.

[0033] The formula for calculating the solubility of water-soluble polysiloxanes is as follows:

[0034]

[0035] Example 1

[0036] A water-soluble polysiloxane (VAPSi) was prepared with a design ratio of 10% methylaminoethylaminopropyl units and 90% methyl vinyl units. 1-9 ).

[0037] 8.6g D4 Vi 185.4 g AEAPMDS, 16.2 g distilled water, and 0.04 g TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 0.5 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was started to remove low-boiling-point methanol, water, and their byproducts to obtain VAPSi. 1-9 .like Figure 2 As shown in (a) of the image, the FT-IR spectrum exhibits typical absorption peaks of the siloxane skeleton and characteristic absorption peaks of each group, proving the successful synthesis of polysiloxane. Figure 3 As shown in (a) in the figure, 1 The characteristic peaks of methyl, vinyl, phenyl and amino groups can be clearly observed in the 1H NMR spectrum. The actual proportion of methyl vinyl repeating units is calculated to be 9.8% and that of methylaminoethylaminopropyl repeating units is 90.2% by peak area integration.

[0038] VAPSi 1-9 Add dropwise to 100 mL of deionized water and keep stirring at 25 °C until VAPSi is achieved. 1-9 Completely dissolve until VAPSi 1-9 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0039] Comparative Example 1:

[0040] Polysiloxanes (VPSi) with a methyl vinyl unit design ratio of 10% and a dimethyl unit design ratio of 90% were prepared. 1-9 ).

[0041] 8.6g D4 Vi 66.6 g of octamethylcyclotetrasiloxane and 0.04 g of TMHA catalyst were added to a three-necked flask; the reaction system was purged with nitrogen three times to isolate oxygen, the temperature was raised to 100 °C for 0.5 h, and then raised to 150 °C for 0.5 h to inactivate the catalyst; the temperature was then lowered to room temperature, and low-boiling-point substances were removed by vacuum distillation. VPSi was obtained with an actual percentage of 10.3% methyl vinyl units and 89.7% dimethyl units. 1-9 .

[0042] VPSi1-9 Add dropwise to 100 mL of deionized water and maintain stirring at 25 °C until VPSi is achieved. 1-9 Completely dissolve until VAPSi 1-9 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0043] Example 2

[0044] The water-soluble polysiloxane (VAPSi) was prepared with a methyl vinyl repeating unit design of 20% and a methylaminoethylaminopropyl repeating unit design of 80%. 2-8 ).

[0045] 17.2g D4 Vi 164.8 g AEAPMDS, 14.4 g distilled water, and 0.04 g TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 1 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. After cooling to room temperature, vacuum distillation was started to remove low-boiling-point methanol, water, and their byproducts, yielding VAPsi with an actual percentage of 20.3% methyl vinyl units and 79.7% methyl aminoethyl aminopropyl units. 2-8 .

[0046] VAPSi 2-8 Add dropwise to 100 mL of deionized water and keep stirring at 25 °C until VAPSi is achieved. 2-8 Completely dissolve until VAPSi 2-8 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0047] Example 3

[0048] The water-soluble polysiloxane (VAPSi) was prepared with a methyl vinyl repeating unit design of 30% and a methylaminoethylaminopropyl repeating unit design of 70%. 3-7 ).

[0049] 25.8 g D4Vi, 144.2 g AEAPMDS, 12.6 g distilled water, and 0.04 g TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 1.5 h, then raised to 150 °C and reacted for another 0.5 h to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was initiated to remove low-boiling-point methanol, water, and their byproducts. VAPSi was obtained with a methyl vinyl unit content of 30.1% and a methylaminoethylaminopropyl unit content of 69.9%. 3-7 .

[0050] VAPSi 3-7 Add dropwise to 100 mL of deionized water and keep stirring at 25 °C until VAPSi is achieved. 3-7 Completely dissolve until VAPSi 3-7 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0051] Example 4

[0052] The water-soluble polysiloxane (VAPSi) was prepared with a methyl vinyl repeating unit design of 40% and a methylaminoethylaminopropyl repeating unit design of 60%. 4-6 ).

[0053] 34.4g D4 Vi 123.6 g of AEAPMDS, 10.8 g of distilled water, and 0.04 g of TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 2 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. After cooling to room temperature, vacuum distillation was started to remove low-boiling-point methanol, water, and their byproducts, yielding VAPsi with an actual percentage of 39.8% methyl vinyl units and 60.2% methyl aminoethyl aminopropyl units. 4-6 .

[0054] VAPSi 4-6 Add dropwise to 100 mL of deionized water and keep stirring at 25 °C until VAPSi is achieved. 4-6 Completely dissolve until VAPSi 4-6 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0055] Example 5

[0056] The water-soluble polysiloxane (VAPSi) was prepared with a methyl vinyl repeating unit design of 50% and a methylaminoethylaminopropyl repeating unit design of 50%. 5-5 ).

[0057] 43g D4 Vi 103g AEAPMDS, 9g distilled water, and 0.04g TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100℃ for 3 hours, then raised to 150℃ for 0.5 hours to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was initiated to remove low-boiling-point methanol, water, and their byproducts. VAPSi was obtained with an actual percentage of 50.3% methyl vinyl units and 49.7% methyl aminoethyl aminopropyl units. 5-5 .

[0058] VAPSi 5-5 Add dropwise to 100 mL of deionized water and keep stirring at 25 °C until VAPSi is achieved. 5-5 Completely dissolve until VAPSi 5-5 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0059] Example 6

[0060] The water-soluble polysiloxane (VAPSi) was designed to contain 60% methyl vinyl repeating units and 40% methylaminoethylaminopropyl repeating units. 6-4 ).

[0061] 51.6g D4 Vi 82.4 g AEAPMDS, 7.2 g distilled water, and 0.04 g TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 4 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was started to remove low-boiling-point methanol, water, and their byproducts. VAPSi was obtained with an actual percentage of 41.1% methyl vinyl units and 58.9% methyl aminoethyl aminopropyl units. 6-4 .

[0062] Add VAPSi6-4 dropwise to 100 mL of deionized water and stir continuously at 25 °C until VAPSi 6-4 Completely dissolve until VAPSi 6-4Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0063] Example 7

[0064] A water-soluble polysiloxane (PhAPSi1-9) was prepared with a methylphenyl repeating unit design of 10% and a methylaminoethylaminopropyl repeating unit design of 90%.

[0065] 13.6g D n Ph 185.4 g of AEAPMDS, 16.2 g of distilled water, and 0.08 g of TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 1 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was initiated to remove low-boiling-point methanol, water, and their byproducts. PhAPSi was obtained with an actual percentage of 9.8% methylphenyl repeating units and 90.2% methylaminoethylaminopropyl repeating units. 1-9 .

[0066] PhAPSi 1-9 Add dropwise to 100 mL of deionized water and maintain stirring at 25 °C until PhAPSi 1-9 Completely dissolved until PhAPSi 1-9 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0067] Example 8

[0068] The water-soluble polysiloxane (PhAPSi) was prepared with a methylphenyl repeating unit design of 20% and a methylaminoethylaminopropyl repeating unit design of 80%. 2-8 ).

[0069] 27.2g D n Ph 164.8 g of AEAPMDS, 14.4 g of distilled water, and 0.08 g of TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 2 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was initiated to remove low-boiling-point methanol, water, and their byproducts. PhAPSi was obtained with a methylphenyl repeating unit content of 19.6% and a methylaminoethylaminopropyl repeating unit content of 80.4%. 2-8 .

[0070] PhAPSi 2-8 Add dropwise to 100 mL of deionized water and maintain stirring at 25 °C until PhAPSi 2-8 Completely dissolved until PhAPSi 2-8 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0071] Example 9

[0072] The water-soluble polysiloxane (PhAPSi) was prepared with a methylphenyl repeating unit design of 30% and a methylaminoethylaminopropyl repeating unit design of 70%. 3-7 ).

[0073] 40.8g D n Ph 144.2 g of AEAPMDS, 12.6 g of distilled water, and 0.07 g of TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 3 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was started to remove low-boiling-point methanol, water, and their byproducts. PhAPSi was obtained with an actual percentage of 30.2% methylphenyl repeating units and 69.8% methylaminoethylaminopropyl repeating units. 3-7 .

[0074] PhAPSi 3-7 Add dropwise to 100 mL of deionized water and maintain stirring at 25 °C until PhAPSi 3-7 Completely dissolved until PhAPSi 3-7 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0075] Example 10

[0076] The water-soluble polysiloxane (PhAPSi) was prepared with a methylphenyl repeating unit design of 40% and a methylaminoethylaminopropyl repeating unit design of 60%. 4-6 ).

[0077] 54.4g D n Ph123.6 g of AEAPMDS, 10.8 g of distilled water, and 0.07 g of TMHA catalyst were added to a three-necked flask. The reaction system was purged with nitrogen three times to isolate oxygen. The temperature was raised to 100 °C and reacted for 3 h, then raised to 150 °C and reacted for 0.5 h to inactivate the catalyst. The mixture was cooled to room temperature, and vacuum distillation was started to remove low-boiling-point methanol, water, and their byproducts. PhAPSi was obtained with an actual percentage of 39.5% methylphenyl repeating units and 60.5% methylaminoethylaminopropyl repeating units. 4-6 .

[0078] PhAPSi 4-6 Add dropwise to 100 mL of deionized water and maintain stirring at 25 °C until PhAPSi 4-6 Completely dissolved until PhAPSi 4-6 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0079] Comparative Example 2:

[0080] The preparation of a polysiloxane (PhPSi) with a methylphenyl repeating unit of 40% and a dimethyl repeating unit of 60% was achieved. 4-6 ).

[0081] 54.4g D n Ph 44.4 g of octamethylcyclotetrasiloxane and 0.04 g of TMHA catalyst were added to a three-necked flask; the reaction system was purged with nitrogen three times to isolate oxygen, the temperature was raised to 100 °C for 3 h, and then raised to 150 °C for 0.5 h to inactivate the catalyst; the temperature was lowered to room temperature, and vacuum distillation was started to remove low-boiling compounds. PhPSi was obtained with a methylphenyl chain ratio of 40.6% and a dimethyl side chain ratio of 59.4%. 4-6 .

[0082] PhPSi 4-6 Add dropwise to 100 mL of deionized water and maintain stirring at 25 °C until PhPSi 4-6 Completely dissolve until PhPSi 4-6 Once no further dissolution occurs, stop adding water, filter out the undissolved portion, and obtain a clear aqueous solution of hydrophilic polysiloxane. Finally, evaporate the solution to obtain the mass of dissolved polysiloxane, and calculate the solubility of the water-soluble polysiloxane using a formula.

[0083] The actual proportion of polysiloxane segments and the solubility test results at 25°C of the polysiloxanes prepared in Examples 1-10 and Comparative Examples 1-2 are shown in Table 1.

[0084] Table 1. Actual percentage and solubility of polysiloxane chain segments.

[0085]

[0086]

[0087] The main difference between Example 1 and Comparative Example 1 is that the polysiloxane in Example 1 contains an aminoethylaminopropyl group, while in Comparative Example 1, a methyl group replaces the aminoethylaminopropyl group. The polysiloxane in Example 1 has a solubility of 60 g / 100 mL, which is significantly higher than that in Comparative Example 1, indicating that the introduction of the aminoethylaminopropyl group imparts hydrophilicity to the polysiloxane. As shown in Table 1, the solubility data of Examples 1-6 and Examples 7-10 show that when the R2 group is consistent, the solubility of the polysiloxane increases with the increase of the aminoethylaminopropyl group content.

[0088] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the present invention by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. A method for preparing a water-soluble polysiloxane, characterized in that, The water-soluble polysiloxane has a structure as shown in Formula I: Equation I; Wherein, R1 is aminoethylaminopropyl, R2 is vinyl or phenyl, and X+Y=100%; The method for preparing the water-soluble polysiloxane is selected from one of the following 1) to 9): 1) Tetramethyltetravinylcyclotetrasiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the tetramethyltetravinylcyclotetrasiloxane is 8.6 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 185.4 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 0.5 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=90.2%, and the solubility of the water-soluble polysiloxane in water is 92 g / 100 mL; 2) Tetramethyltetravinylcyclotetrasiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the tetramethyltetravinylcyclotetrasiloxane is 17.2 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 164.8 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 1 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=79.9%, and the solubility of the water-soluble polysiloxane in water is 78 g / 100 mL; 3) Tetramethyltetravinylcyclotetrasiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the tetramethyltetravinylcyclotetrasiloxane is 25.8 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 144.2 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 1.5 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=69.9%, and the solubility of the water-soluble polysiloxane in water is 54 g / 100 mL; 4) Tetramethyltetravinylcyclotetrasiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the tetramethyltetravinylcyclotetrasiloxane is 34.4 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 123.6 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 2 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=60.2%, and the solubility of the water-soluble polysiloxane in water is 25 g / 100 mL; 5) Tetramethyltetravinylcyclotetrasiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the tetramethyltetravinylcyclotetrasiloxane is 43g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 103g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 3h, and then at 140℃~160℃ for 0.5~1h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=49.7%, and the solubility of the water-soluble polysiloxane in water is 11g / 100mL; 6) Tetramethyltetravinylcyclotetrasiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the tetramethyltetravinylcyclotetrasiloxane is 51.6 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 82.4 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 4 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=41.1%, and the solubility of the water-soluble polysiloxane in water is 2 g / 100 mL; 7) Methylphenylcyclosiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the methylphenylcyclosiloxane is 13.6 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 185.4 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 1 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=90.2%, and the solubility of the water-soluble polysiloxane in water is 86 g / 100 mL; 8) Methylphenylcyclosiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the methylphenylcyclosiloxane is 27.2 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 164.8 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 2 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=80.4%, and the solubility of the water-soluble polysiloxane in water is 36 g / 100 mL; 9) Methylphenylcyclosiloxane, N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane, catalyst, and deionized water are mixed; the methylphenylcyclosiloxane is 40.8 g, and the N-(β-aminoethyl-γ-aminopropyl)methyldimethoxysilane is 144.2 g; the reaction is carried out under an inert atmosphere, first at 90℃~110℃ for 3 h, and then at 140℃~160℃ for 0.5~1 h; after the reaction, the mixture is distilled under reduced pressure to obtain a water-soluble polysiloxane with X=69.8%, wherein the solubility of the water-soluble polysiloxane in water is 10 g / 100 mL; The catalyst includes at least one of tetramethylammonium hydroxide, tetramethylammonium hydroxide silanoate, sodium hydroxide, and potassium hydroxide.

2. The application of the water-soluble polysiloxane obtained by the preparation method according to claim 1 in water-based coatings, cosmetics, drug carriers or environmental protection fields.

Images