Sample needle blockage detection method and sample needle blockage detection device

By obtaining and filtering the pressure value of the sample needle in the sample needle detection system, and calculating the initial pressure value to judge the needle blocking, the problem of low detection accuracy and accuracy of the sample needle blocking needle in the prior art is solved, and the reliability of the detection is improved.

CN119845649APending Publication Date: 2025-04-18SHENZHEN LINKRAY BIOTECH CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202411998611.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2025-04-18

AI Technical Summary

Technical Problem

The existing sample needle plug detection methods have poor accuracy and low accuracy in judgment of needle plugging. They are easily affected by the speed of the syringe when the sample needle is aspirated and the pump and valve switch actions, resulting in false alarms.

Method used

By running the sample needle to the preset position and then lowering it to the preset height, multiple pressure values ​​are obtained every preset interval time since the beginning of the decline, filtering, and calculating the initial pressure value to judge the needle blocking.

Benefits of technology

It significantly improves the accuracy and reliability of sample needle plug detection, reduces data fluctuations and false alarms, and ensures the reliability of the detection results.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119845649A_ABST
    Figure CN119845649A_ABST
Patent Text Reader

Abstract

The invention relates to the technical field of sample needle blocking detection, and discloses a sample needle blocking detection method and a sample needle blocking detection device.The sample needle blocking detection method comprises the steps that after a sample needle runs to a preset position, the sample needle descends to a preset height for operation; when the sample needles start to descend, acquiring pressure values of the plurality of sample needles based on a preset interval time; performing filtering processing on each pressure value; calculating a mean value of the preset number of pressure values after filtering processing, and taking the mean value as an initial pressure value; and according to the pressure value after filtering processing and the initial pressure value, performing needle blockage judgment on the sample needle. The obtained pressure value of the sample needle is filtered, data fluctuation in the sample needle operation process is reduced, the initial pressure value is introduced, the situation that needle blocking is misreported due to the fact that the initial pressure of a sample needle pipeline is abnormal can be avoided, and therefore the accuracy and reliability of sample needle blocking detection are remarkably improved.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention relates to the technical field of sample needle blockage detection, and in particular to a sample needle blockage detection method and a sample needle blockage detection device. Background Art

[0002] In the sample detection system, a sample needle is needed to draw the sample for detection. However, the inner diameter of the sample needle is small. The red blood cells, fibrin or fatty blood contained in the sample may cause the sample needle to be blocked during the sample aspiration, resulting in inaccurate sample detection results. In more serious cases, the corresponding liquid circuit may collapse. If the operator continues to use the sample detection instrument after the sample needle is blocked, it will seriously affect the test results and even damage some components in the instrument. Therefore, the detection of sample needle blockage is particularly important.

[0003] The existing sample needle blockage detection scheme generally uses pressure detection to determine whether the sample needle is blocked. A pressure sensor is installed in the sample detection system to collect the pressure of the sample needle and compare it with the preset pressure to determine whether the needle is blocked. However, the sample needle absorbs very little liquid and the absorption time is short. In addition, it is affected by the speed of the syringe when aspirating the sample on the sample needle pipeline, the pump valve switch and other actions, as well as the performance of the pressure sensor itself, resulting in poor pressure detection accuracy and low accuracy of needle blockage detection. Summary of the invention

[0004] In view of this, the present invention provides a sample needle blockage detection method and a sample needle blockage detection device to solve the problems of poor precision in sample needle blockage detection and low accuracy in needle blockage judgment.

[0005] In a first aspect, the present invention provides a method for detecting a sample needle blockage, comprising:

[0006] After the sample needle moves to a preset position, it is lowered to a preset height for operation;

[0007] When the sample needle starts to descend, a plurality of pressure values ​​m of the sample needle are obtained based on a preset interval time;

[0008] Performing filtering processing on each of the pressure values ​​m;

[0009] The preset number of pressure values ​​m after filtering i Calculate the mean value as the initial pressure value m0;

[0010] According to the pressure value m after filtering i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked.

[0011] Beneficial effects: In the sample needle clogging detection method of the present invention, starting from when the sample needle begins to descend, at preset intervals, multiple pressure values m of the sample needle are obtained, and the obtained pressure values m of the sample needle are filtered to reduce data fluctuations during the operation of the sample needle. The introduction of the initial pressure value m0 can avoid false alarms of needle clogging caused by abnormal initial pressure in the sample needle pipeline, thereby significantly improving the accuracy and reliability of sample needle clogging detection.

[0012] In an optional implementation manner, the filtering process for each of the pressure values includes:

[0013] Obtain the total number T of each of the pressure values and the current i-th data, and preset the filtering parameter N;

[0014] When i ≤ N, the i-th pressure value m after filtering i = the average value of the pressure values m from the (0)-th to the i-th;

[0015] When N < i ≤ T - N, obtain the pressure sum m sum of the (i - N)-th to the (i + N)-th, the maximum pressure value m max and the minimum pressure value m min , and the i-th pressure value m after filtering i =(m sum -m max -m min ) / (2N - 1).

[0016] When i > T - N, the i-th pressure value m after filtering i = the average value of the pressure values m from the (T - N)-th to the i-th.

[0017] Beneficial effects: By performing special filtering on each pressure value, it is possible to reduce data fluctuations caused by the influence of the speed of syringe sampling on the sample needle pipeline and actions such as the opening and closing of the pump valve, thereby improving the accuracy and reliability of the obtained pressure values and reducing false alarms of needle clogging.

[0018] In an optional implementation manner, the determination of whether the sample needle is clogged based on the size of the pressure value m i after filtering and the initial pressure value m0 includes:

[0019] During the sample needle sampling stage, when the pressure value m i after filtering minus the initial pressure value m0 is less than the low pressure threshold L, it is determined that the sample needle is clogged during sampling.

[0020] Beneficial effects: By comparing the low pressure threshold L and the pressure value m iThe difference between the pressure value m0 and the initial pressure value can be used to determine whether the sample needle is blocked during sample aspiration, and the detection process is simple and controllable.

[0021] In an optional embodiment, during the sample aspiration stage, when the pressure value m after filtering is i When the initial pressure value m0 minus the initial pressure value is less than the low pressure threshold L, it is determined that the sample needle is blocked during sample aspiration, specifically including:

[0022] In the sample needle aspiration stage, when the pressure value m after the first preset number of filtering processes is i When the initial pressure value m0 minus the initial pressure value is less than the low pressure threshold value L, it is determined that the sample needle is blocked during sample aspiration.

[0023] Beneficial effect: When the pressure value m after the first preset number of filtering processes is i When the value minus the initial pressure value m0 is less than the low pressure threshold L, it is determined that the sample needle is blocked during sample aspiration, which can reduce false alarms of needle blockage during the sample needle aspiration stage and further improve the accuracy of needle blockage detection.

[0024] In an optional embodiment, when the sample needle starts to descend, a plurality of pressure values ​​m of the sample needle are obtained based on a preset interval time, specifically including:

[0025] During the sample needle aspiration stage, the pressure value m of the sample needle is acquired every 0.1 ms to 15 ms from the start of the sample needle's descent to the end of the sample aspiration.

[0026] Beneficial effect: By setting a preset interval time for obtaining the pressure value m of the sample needle, the change of the pressure value m can be detected in real time, the detection error caused by instantaneous fluctuations can be reduced, and the reliability of the detection result can be improved.

[0027] In an optional implementation, the pressure value m after filtering is i and the initial pressure value m0 to determine whether the sample needle is blocked, including:

[0028] During the sample needle cleaning phase, when the pressure value m after filtering is i When the value m0 minus the initial pressure is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning.

[0029] Beneficial effect: By comparing the high pressure threshold H and the pressure value m after filtering i The difference between the pressure value m0 and the initial pressure value m0 can be used to determine whether the sample needle is blocked during cleaning, and the detection process is simple and controllable.

[0030] In an optional embodiment, during the sample needle cleaning stage, when the pressure value m after filtering is iWhen the initial pressure value m0 minus the initial pressure value is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning, specifically including:

[0031] In the sample needle cleaning stage, when the second preset number of consecutive filtered pressure values ​​m i When the value m0 minus the initial pressure is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning.

[0032] Beneficial effect: When the pressure value m after the second preset number of filtering processes is i When the value m0 minus the initial pressure is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning, which can reduce false alarms of needle blockage during the sample needle cleaning stage and further improve the accuracy of needle blockage detection.

[0033] In an optional implementation, the preset filtering parameter N is 2 to 15.

[0034] Beneficial effect: By limiting the preset filtering parameter N, the i-th pressure value m after filtering can be accurately calculated. i .

[0035] In an optional implementation, the filtering process is performed on a preset number of the plurality of pressure values ​​m i After calculating the mean value as the initial pressure value m0, the following steps are also included:

[0036] When the initial pressure value m0 is greater than the initial pressure threshold M, it is determined that the pressure of the sample needle is abnormal.

[0037] Beneficial effect: By setting the initial pressure threshold M and comparing the initial pressure value m0 with the initial pressure threshold M, when the initial pressure value m0 is greater than the initial pressure threshold M, it can be determined that the pressure of the sample needle is abnormal, and the operator can be promptly reminded that the current needle blockage has become abnormal.

[0038] In a second aspect, the present invention further provides a sample needle blockage detection device, comprising:

[0039] A driving module is used to drive the sample needle to move to a preset position and then descend to a preset height for operation;

[0040] An acquisition module, used for acquiring a plurality of pressure values ​​m of the sample needles based on a preset interval time when the sample needles start to descend;

[0041] A filtering processing module, used for filtering each of the pressure values ​​m;

[0042] A calculation module is used to calculate a preset number of the pressure values ​​m after filtering. i Calculate the mean value as the initial pressure value m0;

[0043] The judgment module is used to determine the pressure value m after filtering. i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked.

[0044] Beneficial effect: The sample needle blockage detection device of the present invention obtains pressure values ​​m of multiple sample needles at preset intervals since the sample needle begins to descend, and filters the obtained pressure values ​​m of the sample needles, thereby reducing data fluctuations during the operation of the sample needles. The introduction of the initial pressure value m0 can avoid false alarms of needle blockage caused by abnormal initial pressure in the sample needle pipeline, thereby significantly improving the accuracy and reliability of sample needle blockage detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0045] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0046] Figure 1 A schematic diagram of a sample needle blockage detection method according to an embodiment of the present invention;

[0047] Figure 2 A flow chart of a sample needle blockage detection method according to an embodiment of the present invention;

[0048] Figure 3 A schematic diagram of a sample needle blockage detection device according to an embodiment of the present invention;

[0049] Figure 4 It is a waveform curve diagram of a blocked needle and an unblocked needle during the sample aspiration stage of a sample needle in an embodiment of the present invention;

[0050] Figure 5 It is a waveform curve diagram of a blocked needle and an unblocked needle during the cleaning stage of a sample needle in an embodiment of the present invention;

[0051] Figure 6 It is a waveform curve diagram showing abnormal and normal initial pressure of the sample needle in an embodiment of the present invention;

[0052] Figure 7 Graph showing the pressure values ​​of the sample needle after filtering and without filtering according to an embodiment of the present invention.

[0053] Description of reference numerals:

[0054] 100, driving module; 200, acquiring module; 300, filtering processing module; 400, calculating module; 500, judging module. DETAILED DESCRIPTION

[0055] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present invention.

[0056] Combine the following Figures 1 to 7 , describing an embodiment of the present invention.

[0057] According to an embodiment of the present invention, on the one hand, Figure 1 As shown, a method for detecting a sample needle blockage is provided, comprising:

[0058] S100, after the sample needle moves to a preset position, it is lowered to a preset height for operation.

[0059] S200 , when the sample needle starts to descend, the pressure values ​​m of the plurality of sample needles are obtained based on a preset interval time.

[0060] S300 , filter each pressure value m.

[0061] S400, filtering a preset number of pressure values ​​m i Calculate the mean value as the initial pressure value m0.

[0062] S500, according to the pressure value m after filtering i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked.

[0063] The sample needle blockage detection method provided in the embodiment of the present invention obtains pressure values ​​m of multiple sample needles at preset intervals since the sample needle begins to descend, and filters the obtained pressure values ​​m of the sample needles, thereby reducing data fluctuations during the operation of the sample needles. The initial pressure value m0 is introduced, which can avoid false alarms of needle blockage caused by abnormal initial pressure of the sample needle pipeline, thereby significantly improving the accuracy and reliability of sample needle blockage detection.

[0064] It should be noted that in the embodiments of the present invention, the pressure value m of the sample needle can be obtained through a pressure sensor, and the pressure signal collected by the pressure sensor can be obtained in real time through a sensor conditioning chip. At the same time, the sensor conditioning chip provides a constant voltage source for the pressure sensor, which can amplify and filter the pressure signal, and can also convert the pressure signal into a digital signal for output. By configuring the values of the registers of the sensor conditioning chip through a controller, the amplification factor and sampling rate of the sensor conditioning chip can be controlled, etc. The controller can also read the digital signal output by the sensor conditioning chip and perform a needle blockage judgment. The sensor conditioning chip is simpler and more controllable compared to traditional circuit designs. The controller can select any existing controller according to needs, such as an MCU.

[0065] In one embodiment, S300, filtering each pressure value, includes:

[0066] S310, obtaining the total number T of each pressure value and the current i-th data, and presetting a filtering parameter N.

[0067] S320, when i ≤ N, then the i-th pressure value m after filtering i = the average value of the pressure values m from the 0-th to the i-th.

[0068] S330, when N < i ≤ T - N, then obtain the sum m of the pressures from the (i - N)-th to the (i + N)-th sum , the maximum pressure value m max and the minimum pressure value m min , the i-th pressure value m after filtering i =(m sum -m max -m min ) / (2N - 1).

[0069] S340, when i > T - N, then the i-th pressure value m after filtering i = the average value of the pressure values m from the (T - N)-th to the i-th.

[0070] The waveforms of the unfiltered pressure values and the filtered pressure values are as Figure 7 shown. It can be seen that in the embodiments of the present invention, by filtering each pressure value, the data fluctuation caused by the influence of the speed of syringe sampling on the sample needle pipeline and the actions such as the opening and closing of the pump valve can be significantly reduced, thereby improving the accuracy and reliability of the obtained pressure values and reducing false alarms of needle blockage.

[0071] Furthermore, in one embodiment, the preset filtering parameter N is from 2 to 15, for example, N is 10. By restricting the preset filtering parameter N, the i-th pressure value m after filtering can be accurately calculated i .

[0072] Further, in one embodiment, S400, a preset number of pressure values ​​m after filtering are i Calculate the mean value as the initial pressure value m0, and also include:

[0073] The first 10 pressure values ​​after filtering are i Calculate the mean as the initial pressure value m0, and then obtain the pressure value m after filtering. i to determine if the needle is blocked.

[0074] Of course, in other embodiments, other preset pressure values ​​m may be selected as required. i Calculate the average value as the initial pressure value m0, for example, 5, 20, etc.

[0075] In one embodiment, S500, according to the pressure value m after filtering, i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked, including:

[0076] S510, in the sample needle aspiration stage, when the pressure value m after filtering processing i When the initial pressure value m0 minus the pressure value m0 is less than the low pressure threshold L, it is determined that the sample needle is blocked during sample aspiration. By comparing the low pressure threshold L and the pressure value m after filtering i The difference between the pressure value m0 and the initial pressure value can be used to determine whether the sample needle is blocked during sample aspiration, and the detection process is simple and controllable.

[0077] Specifically, the low-pressure threshold L can be set according to actual needs. The low-pressure threshold L can be selected to be 200 to 1200 (AD value, identifiable data after computer conversion), for example, the low-pressure threshold L is 500.

[0078] Further, in one embodiment, S510, in the sample needle aspiration stage, when the pressure value m after filtering is i When the initial pressure value m0 minus the initial pressure value is less than the low pressure threshold L, it is determined that the sample needle is blocked during sample aspiration, specifically including:

[0079] S511, in the sample needle aspiration stage, when the pressure value m after the first preset number of continuous filtering processes is i When the initial pressure value m0 minus the pressure m0 is less than the low pressure threshold value L, it is determined that the sample needle is blocked during the sample aspiration process. This can reduce false positives of needle blockage during the sample aspiration process and further improve the accuracy of needle blockage detection.

[0080] Specifically, the first preset number can be selected according to actual needs, for example, 2 to 10, and specifically, the first preset number is 5. In the sample needle aspiration stage, the waveforms of the sample needle aspiration with blocked needle and unblocked needle are as follows Figure 4 shown.

[0081] During the sample needle aspiration stage of the sample detection system, the sample needle, the sample needle drive motor, the sample needle syringe and the solenoid valve cooperate to complete the sample aspiration action. First, the sample needle drive motor drives the sample needle to move above a certain sample position, and then drives the sample needle down to a certain height below the sample liquid surface and stops. Then, the sample syringe and the solenoid valve cooperate to absorb a certain amount of sample. After the aspiration is completed, the sample needle drive motor drives the sample needle to rise.

[0082] like Figure 2 As shown in the figure, when the sample needle starts to descend, the needle blocking detection device installed on the sample pipeline starts the needle blocking detection data sampling function until the sample syringe stops aspirating liquid. When the sample needle is being cleaned, when five consecutive filtered pressure values ​​m i When the initial pressure value m0 minus the initial pressure value is less than the low pressure threshold value L, it is determined that the sample needle is blocked during sample aspiration and an alarm message is issued. Otherwise, it indicates that the sample needle is not blocked during sample aspiration and the sample detection system continues to operate normally.

[0083] In one embodiment, S200, when the sample needle starts to descend, based on a preset interval time, the pressure values ​​m of the multiple sample needles are obtained, specifically including:

[0084] S210, in the sample needle aspiration stage, from the beginning of the sample needle descending to the end of the sample aspiration action, the pressure value m of the sample needle is obtained every 0.1ms to 15ms, for example, every 10ms. By setting a preset interval time for obtaining the pressure value m of the sample needle, the change of the pressure value m can be detected in real time, the detection error caused by instantaneous fluctuations can be reduced, and the reliability of the detection result can be improved.

[0085] In one embodiment, S500, according to the pressure value m after filtering, i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked, including:

[0086] S520, in the sample needle cleaning stage, when the pressure value m after filtering is i When the initial pressure value m0 minus the pressure value m0 is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning. By comparing the high pressure threshold H and the pressure value m after filtering i The difference between the pressure value m0 and the initial pressure value m0 can be used to determine whether the sample needle is blocked during cleaning, and the detection process is simple and controllable.

[0087] Specifically, the high pressure threshold H can be set according to actual needs. The high pressure threshold H can be selected from 25000 to 35000 (AD value), for example, the high pressure threshold H is 30000.

[0088] Further, in one embodiment, S520, in the sample needle cleaning stage, when the pressure value m after filtering is iWhen the initial pressure value m0 minus the initial pressure value is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning, specifically including:

[0089] S521, in the sample needle cleaning stage, when the pressure value m after the second preset number of filtering processes is i When the initial pressure value m0 minus the pressure m0 is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning. This can reduce false positives of blocked needles during the sample needle cleaning phase and further improve the accuracy of blocked needle detection.

[0090] Specifically, the second preset number can be selected according to actual needs, for example, 2 to 10, and specifically, the second preset number is 5. In the sample needle cleaning stage, the waveforms of the inner and outer walls of the sample needle are as follows: Figure 5 shown.

[0091] During the sample needle cleaning stage of the sample detection system, the sample needle driving motor is also required to drive the sample needle to move above the cleaning tank, and then drive the sample needle down into the cleaning tank for cleaning. After cleaning, the sample needle driving motor drives the sample needle up.

[0092] Similarly, when the sample needle starts to descend, the needle blockage detection device installed on the sample pipeline starts the needle blockage detection data sampling function until the cleaning operation is completed. i When the initial pressure value m0 minus the initial pressure value is greater than the high pressure threshold H, it is determined that the sample needle is blocked during the cleaning of the inner and outer walls, and an alarm message is issued. Otherwise, it indicates that the sample needle is not blocked during the cleaning of the inner and outer walls, and the sample detection system continues to operate normally.

[0093] In one embodiment, S400, a preset number of pressure values ​​m after filtering are processed. i After calculating the mean value as the initial pressure value m0, the following steps are also included:

[0094] S600, when the initial pressure value m0 is greater than the initial pressure threshold M, it is determined that the pressure of the sample needle is abnormal. By setting the initial pressure threshold M and comparing the initial pressure value m0 with the initial pressure threshold M, it is possible to determine that the pressure of the sample needle is abnormal when the initial pressure value m0 is greater than the initial pressure threshold M, and to promptly remind the operator that the current needle blockage has been abnormal.

[0095] Specifically, the initial pressure threshold M can be set according to actual needs, and the initial pressure threshold M can be selected from 1500 to 2500 (AD value), for example, the initial pressure threshold M is 2000. The abnormal pressure waveform of the sample needle is different from the normal waveform. Figure 6 shown.

[0096] According to an embodiment of the present invention, on the other hand, Figure 3As shown, a sample needle blockage detection device is also provided, which mainly includes: a driving module 100, an acquisition module 200, a filtering processing module 300, a calculation module 400 and a judgment module 500. The driving module 100 is used to drive the sample needle to run to a preset position and then descend to a preset height to operate. The acquisition module 200 is used to obtain the pressure values ​​m of multiple sample needles based on a preset interval time when the sample needle starts to descend. The filtering processing module 300 is used to filter each pressure value m. The calculation module 400 is used to filter the preset number of multiple pressure values ​​m after filtering. i The mean value is calculated as the initial pressure value m0. The judgment module 500 is used to determine the pressure value m0 after filtering. i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked.

[0097] The sample needle blockage detection device provided in the embodiment of the present invention obtains pressure values ​​m of multiple sample needles at preset intervals since the sample needle starts to descend, and filters the obtained pressure values ​​m of the sample needles, thereby reducing data fluctuations during the operation of the sample needles. The initial pressure value m0 is introduced to avoid false alarms of needle blockage caused by abnormal initial pressure of the sample needle pipeline, thereby significantly improving the accuracy and reliability of sample needle blockage detection.

[0098] Although the embodiments of the present invention have been described in conjunction with the accompanying drawings, those skilled in the art may make various modifications and variations without departing from the spirit and scope of the present invention, and such modifications and variations are all within the scope defined by the appended claims.

Claims

1. A method for detecting a sample needle blockage, characterized in that: include: After the sample needle moves to a preset position, it is lowered to a preset height for operation; When the sample needle starts to descend, a plurality of pressure values ​​m of the sample needle are obtained based on a preset interval time; Performing filtering processing on each of the pressure values ​​m; The preset number of pressure values ​​m after filtering i Calculate the mean value as the initial pressure value m0; According to the pressure value m after filtering i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked.

2. The sample needle blockage detection method according to claim 1, characterized in that: The filtering process of each of the pressure values ​​comprises: Obtain the total number T of each of the pressure values ​​and the current i-th data, and preset the filtering parameter N; When i≤N, the i-th pressure value m after filtering is i = the average of the pressure values ​​m from (0) to (i); When N < i ≤ T - N, the pressures from the (i - N)-th to the (i + N)-th and m are obtained sum , the maximum pressure value m max and the minimum pressure value m min , the i-th pressure value m after filtering processing i = (m sum - m max - m min ) / (2N - 1); When i>TN, the i-th pressure value m after filtering is i = the average of the pressure values ​​m from (TN)th to (i)th.

3. The method for detecting needle blockage of a sample needle according to claim 1, characterized in that: According to the pressure value m after filtering i and the initial pressure value m0 to determine whether the sample needle is blocked, including: In the sample needle aspiration stage, when the pressure value m after filtering is i When the initial pressure value m0 minus the initial pressure value is less than the low pressure threshold value L, it is determined that the sample needle is blocked during sample aspiration.

4. The method for detecting needle blockage of a sample needle according to claim 3, characterized in that: In the sample needle aspiration stage, when the pressure value m after filtering is i When the initial pressure value m0 minus the initial pressure value is less than the low pressure threshold L, it is determined that the sample needle is blocked during sample aspiration, specifically including: In the sample needle aspiration stage, when the pressure value m after the first preset number of filtering processes is i When the initial pressure value m0 minus the initial pressure value is less than the low pressure threshold value L, it is determined that the sample needle is blocked during sample aspiration.

5. The method for detecting needle blockage of a sample needle according to claim 3, characterized in that: When the sample needle starts to descend, based on a preset interval time, obtaining a plurality of pressure values ​​m of the sample needle specifically includes: During the sample needle aspiration stage, the pressure value m of the sample needle is acquired every 0.1 ms to 15 ms from the start of the sample needle's descent to the end of the sample aspiration.

6. The method for detecting needle blockage of a sample needle according to claim 1, characterized in that: According to the pressure value m after filtering i and the initial pressure value m0 to determine whether the sample needle is blocked, including: During the sample needle cleaning phase, when the pressure value m after filtering is i When the value m0 minus the initial pressure is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning.

7. The sample needle blockage detection method according to claim 6, characterized in that: In the sample needle cleaning stage, when the pressure value m after filtering is i When the initial pressure value m0 minus the initial pressure value is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning, specifically including: In the sample needle cleaning stage, when the second preset number of consecutive filtered pressure values ​​m i When the value m0 minus the initial pressure is greater than the high pressure threshold H, it is determined that the sample needle is blocked during cleaning.

8. The sample needle blockage detection method according to claim 2, characterized in that: The preset filtering parameter N is 2 to 15.

9. The sample needle blockage detection method according to any one of claims 1 to 8, characterized in that: The preset number of the plurality of pressure values ​​m after filtering is i After calculating the mean value as the initial pressure value m0, the following steps are also included: When the initial pressure value m0 is greater than the initial pressure threshold M, it is determined that the pressure of the sample needle is abnormal.

10. A sample needle blockage detection device, characterized in that: include: A driving module (100) is used to drive the sample needle to move to a preset position and then descend to a preset height to perform operation; An acquisition module (200) is used to acquire a plurality of pressure values ​​m of the sample needles based on a preset interval time when the sample needles begin to descend; A filtering processing module (300), used for performing filtering processing on each of the pressure values ​​m; A calculation module (400) is used to calculate a preset number of pressure values ​​m after filtering. i Calculate the mean value as the initial pressure value m0; The judgment module (500) is used to determine the pressure value m after filtering. i The size of the initial pressure value m0 is used to determine whether the sample needle is blocked.