Full-automatic micro liquid separator

By designing flat tube, recessed notch and arc-shaped baffle structures in the micro-sparator, the problem of gas mixing during the liquid separation process is solved, and the aliquoting quality and stability of the sample solution are improved.

CN119858689APending Publication Date: 2025-04-22SHENZHEN LEMNISCARE MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202411995804.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2025-04-22

AI Technical Summary

Technical Problem

During the dispensing process, existing trace liquid dispensers tend to mix a large amount of gas into the liquid, resulting in a decrease in the quality of the sample solution and even a foam surface layer, affecting subsequent detection and use.

Method used

A fully automatic trace dispenser is designed, adopting a flat tube, a recessed notch and an arcuate baffle structure, which guides the flow through the A and B sections of the inner wall of the flat tube, and uses the arcuate baffle to guide the liquid into the center of the container to avoid liquid impact and irregular flow.

Benefits of technology

It effectively avoids the collision between liquids and irregular flow during the liquid separation process, reduces gas mixing, improves the aliquoting quality of the sample solution, and ensures the stability and accuracy of the aliquoting process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a full-automatic micro liquid dispenser which comprises equipment, the side face of a liquid dispensing structure is communicated with a plurality of connecting hoses, flat pipes are fixed to the ends of the connecting hoses, a sunken notch is integrally formed in one side of each flat pipe, and each flat pipe is of a flat duckbilled structure as a whole. The cross section of the joint of the upper port of the flat pipe and the connecting hose is circular, the outlet of the lower port of the flat pipe is arc-shaped, and the flat pipe is gradually expanded outwards in an involute shape from top to bottom. By arranging the flat pipe, the concave notch and the arc-shaped baffle structure, when liquid gradually flows into the flat pipe through the connecting hose, the liquid in the flat pipe is obliquely concentrated towards one side of the flat pipe and is dispersed towards the outer side to form a compound-state flow track, so that a large amount of gas is prevented from being mixed into the liquid when the liquid is continuously discharged, and the liquid is prevented from entering the flat pipe. And therefore, the split charging quality of the sample solution is further ensured.
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Description

Technical Field

[0001] The present invention relates to the technical field of liquid medicine packaging, and more specifically, to a fully automatic micro-liquid dispenser. Background Art

[0002] The automatic micro-dispenser mainly adopts the principle of syringe pump connected to pump, controls the on-off to realize liquid dispensing, and adopts a uniquely designed micro-peristaltic pump structure to provide highly precise and highly consistent rapid dispensing operation, allowing experimenters to free their hands. It is mainly used for ELISA plates, blood coagulation hard plates, and blood coagulation soft plates. The entire plate or any column can be selected for quantitative or non-quantitative dispensing, etc. For the dispensing of reagents or other liquids, the operation is automated, fast and simple, which reduces the intensity of manual work while greatly improving efficiency and accuracy. It is widely used in laboratories, pre-test processing, animal husbandry, product production and packaging and other fields.

[0003] In the current use of micro-dispensers, since the gun tip part (pipette tip) of the dispenser is usually designed to be a pointed cone, when dispensing, when the gradually discharged liquid is vertically injected into the interior of the container from top to bottom, the discharged liquid will be accelerated by the gun tip (according to Bernoulli's principle, when the fluid passes through the interior of the gun tip with a reduced volume from a pipe of normal volume, the pressure will decrease and the flow rate will increase), and directly impact the upper part of the bottom inner wall of the container, and collide and flow with the subsequently discharged liquid, so that a large amount of gas is easily mixed into it, and after the pipetting is completed and the liquid is left to stand for a period of time, the gas will form a foam surface layer on the surface of the liquid that is difficult to eliminate, thereby affecting the subsequent liquid detection and use. When the foam situation is serious, the sample solution of the batch will be scrapped. Summary of the invention

[0004] In order to overcome the above-mentioned defects of the prior art, an embodiment of the present invention provides a fully automatic micro-dispenser, which provides a flat tube, a recessed notch and an arc-shaped baffle structure, and utilizes the mutual cooperation of the several. When the liquid gradually flows into the flat tube through the connecting hose, the liquid is gradually guided toward the other side through the arc-shaped trajectories of section A and section B on one side of the inner wall of the flat tube. At the same time, the liquid is diffused and diverted outward in a fan shape along the inner wall of the flat tube that expands outward in an involute shape, and finally flows out from the arc-shaped outlet end at the bottom of the flat tube, and slowly flows toward the center of the container along its inner wall, thereby avoiding the problem that the liquid continuously collides with each other and flows irregularly when being continuously discharged, thereby mixing a large amount of gas therein and affecting the quality of the sample solution. The packaging quality of the sample solution is further ensured to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a fully automatic micro-dispenser, comprising a device, wherein the inside of the device is electrically connected to an operation screen, a container rack is placed on the top surface of the device, a liquid separation structure is arranged on the side of the device, a fixed slide rail is arranged on the top of the device and on one side of the liquid separation structure, a plurality of connecting hoses are arranged on the side of the liquid separation structure, a plurality of connecting hoses are fixed to the ends of the plurality of connecting hoses, a recessed notch is integrally formed on one side of the flat tube, the flat tube is a flat duckbill structure as a whole, the cross section of the upper port of the flat tube at the connection with the connecting hose is circular, the outlet shape of the lower port is arc-shaped, and the shape of the flat tube from top to bottom gradually expands outward in an involute shape, that is, the radius of the circular cross section of the top end of the flat tube is smaller than the radius value of the arc at the bottom end; The inner wall track formed by the recessed notch on the inner side of the flat tube is divided into two arc tracks, A and B, wherein the overall curvature of the A section is smaller than the overall curvature of the B section, and the overall length of the B section is larger than the overall length of the A section. A tangent is drawn on the outer side of the arc track of the B section, and the angle between the extended line of the tangent and the vertical inner wall of the other side of the flat tube is less than 90°; An arc-shaped baffle is fixedly installed on one side of the bottom end of the flat tube, and the arc-shaped baffle includes an inner arc-shaped surface, the bottom end of the inner arc-shaped surface is connected to the outer arc-shaped surface, and a notch is formed below the connection between the inner arc-shaped surface and the outer arc-shaped surface, the arc-shaped convex directions of the inner arc-shaped surface and the outer arc-shaped surface are oppositely distributed, and the inner arc-shaped surface and the outer arc-shaped surface are transitioned by a rounded shape, and the notch is located as a whole at an obliquely lower position of the inner arc-shaped surface.

[0006] In a preferred embodiment, the connecting hose is seamlessly connected to the flat tube, and both sides of the bottom outlet of the flat tube are rounded.

[0007] In a preferred embodiment, the left and right sides of the arc-shaped baffle respectively extend to the bottom rounded corners of the flat tube.

[0008] In a preferred embodiment, the inner side of the arc-shaped baffle extends a distance toward the inner wall of the flat tube, and the surface of the arc-shaped baffle is coated with a layer of hydrophobic layer material.

[0009] In a preferred embodiment, the overall width of the flat tube increases from top to bottom.

[0010] Technical effects and advantages of the present invention: The present invention arranges a flat tube, a recessed notch and an arc-shaped baffle structure, and utilizes the mutual cooperation of the structures. When liquid gradually flows into the flat tube through a connecting hose, the liquid is gradually guided toward the other side through the arc-shaped trajectories of section A and section B on one side of the inner wall of the flat tube. At the same time, the liquid is diffused and diverted outward in a fan-shaped manner along the inner wall of the flat tube that expands outward in an involute shape, that is, the liquid is concentrated in an inclined manner toward one side of the flat tube, and diverted outward in a dispersed manner in a composite flow trajectory, and finally flows out from the arc-shaped outlet end at the bottom end of the flat tube. At this time, the fluid flows from the outlet of the flat tube to the inner wall surface of the container in a fan-shaped manner, and slowly flows toward the center of the container by adhering to the inner wall thereof, thereby avoiding the problem that the liquid continuously collides with each other and flows irregularly when being continuously discharged, thereby mixing a large amount of gas therein and affecting the quality of the sample solution, and further ensuring the packaging quality of the sample solution. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 It is a schematic diagram of the three-dimensional structure of the flat tube of the present invention; Figure 3 It is a schematic diagram of the connecting hose and flat tube structure of the present invention; Figure 4 This is a schematic diagram of the internal structure of the flat tube input end of the present invention; Figure 5 It is a schematic diagram of a partially enlarged structure of the bottom end of the flat tube of the present invention; Figure 6 Schematic diagrams of the flat tube of the present invention at multiple angles; Figure 7 It is a schematic diagram of the structure of the flat tube of the present invention from top and bottom view; Figure 8 This is a schematic diagram of the structure of the lower outlet end of the flat tube of the present invention; Fig. 9 It is a schematic diagram of a partial cross-sectional structure of one side of a flat tube of the present invention; Fig.10 It is a schematic diagram of the cross-sectional structure of the connecting hose and the flat tube of the present invention; Fig.11 Schematic diagram of the cross-sectional structure of the arc-shaped baffle of the present invention; Fig.12 It is a schematic diagram of the flow direction of the solution from the connecting hose to the flat tube of the present invention; Fig.13 It is a schematic diagram of the inner wall shape of a half-section of a flat tube of the present invention; Fig.14 The figure is a schematic diagram of the flow direction of the solution inside the flat tube of the present invention when viewed from an upward angle.

[0012] The accompanying drawings are marked as follows: 1. equipment; 2. operating screen; 3. container rack; 4. liquid separation structure; 5. fixed slide rail; 6. connecting hose; 7. flat tube; 8. recessed notch; 9. arc-shaped baffle; 91. inner arc-shaped surface; 92. outer arc-shaped surface; 93. notch. DETAILED DESCRIPTION

[0013] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0014] As attached Figure 1 To Attachment Fig.14 The fully automatic micro-dispenser shown in the figure comprises a device 1, wherein the inside of the device 1 is electrically connected to an operation screen 2, a container rack 3 is placed on the top surface of the device 1, a liquid separation structure 4 is arranged on the side of the device 1, a fixed slide rail 5 is arranged on the top of the device 1 and on one side of the liquid separation structure 4, a plurality of connecting hoses 6 are arranged on the side of the liquid separation structure 4, a flat tube 7 is fixed to the ends of the plurality of connecting hoses 6, a recessed notch 8 is integrally formed on one side of the flat tube 7, the flat tube 7 is in a flat duckbill shape as a whole, and the upper port of the flat tube 7 is connected to the connecting hose The cross section of the connection of the tube 6 is circular, and the outlet shape of the lower port is arc-shaped. The shape of the flat tube 7 from top to bottom gradually expands outward in an involute shape, that is, the radius of the circular cross section of the top end of the flat tube 7 is smaller than the radius of the arc at the bottom end. By using the above arrangement, it is ensured that when the fluid flows into the flat tube 7, it can follow the inner wall of the flat tube 7 to perform a fan-shaped diffusion and diversion process outward, thereby reducing the speed of the liquid flowing into the container and increasing the inflow area of ​​the liquid, thereby reducing the liquid surface pressure in the fluid input container, further avoiding the generation of persistent foam, and improving the packaging quality of the sample solution; The inner wall track formed by the recessed notch 8 on the inner side of the flat tube 7 is divided into two arc tracks, A and B, wherein the overall curvature of the A section is smaller than the overall curvature of the B section, and the overall length of the B section is larger than the overall length of the A section. A tangent is made on the outer side of the arc track of the B section, and the angle between the extended line of the tangent and the vertical inner wall on the other side of the flat tube 7 is less than 90°. Through the above arrangement, by using the different curvatures of the two arc tracks A and B, it is ensured that when the sample solution is guided, the whole process is from slow to fast, thereby improving the controllability of the sample solution when it is drained, making the fluid direction consistent and not prone to confusion. Moreover, by making the angle between the extended line of the tangent of the outer side of the arc track of the B section and the vertical inner wall on the other side of the flat tube 7 less than 90°, the drained solution will flow to the vertical inner wall of the flat tube 7 at an acute angle, thereby increasing the adhesion between the two, and will not cause excessive interference in the flow direction to the solution originally flowing from top to bottom, thereby improving the stability of the liquid transported by the flat tube 7; An arc-shaped baffle plate 9 is fixedly installed on one side of the bottom end of the flat tube 7, and the arc-shaped baffle plate 9 includes an inner arc-shaped surface 91, and the bottom end of the inner arc-shaped surface 91 is connected to the outer arc-shaped surface 92, and a notch 93 is formed below the connection between the inner arc-shaped surface 91 and the outer arc-shaped surface 92, and the arc-shaped convex directions of the inner arc-shaped surface 91 and the outer arc-shaped surface 92 are oppositely distributed, and the inner arc-shaped surface 91 and the outer arc-shaped surface 92 are transitioned by a rounded shape, and the notch 93 is located at a position obliquely below the inner arc-shaped surface 91 as a whole, through the upper According to the above arrangement, when the liquid flows out of the output port of the flat tube 7, the inner curved surface 91 provided below the output port can be used to guide the final output direction of the liquid so that it flows into the direction of the inside of the container, thereby further increasing the controllability of the fluid movement direction. At the same time, the notch 93 structure formed below the connection between the inner curved surface 91 and the outer curved surface 92 can be used to prevent the liquid from being guided to the lowest point of the outer curved surface 92, thereby preventing the liquid from dripping intermittently at the output tail end, thereby further ensuring the quality of its packaging work.

[0015] The connecting hose 6 and the flat tube 7 are seamlessly connected, and both sides of the bottom outlet of the flat tube 7 are rounded.

[0016] For details, please refer to the attached manual Figure 5 -Attached Figure 6 The left and right sides of the arc-shaped baffle plate 9 extend to the bottom rounded corners of the flat tube 7 respectively.

[0017] The specific implementation method is as follows: by utilizing the setting of the extension track of the arc-shaped baffle plate 9, it can restrict the flow direction of the solution on one side of the flat tube 7, ensuring that it flows out on one side opposite to the inner wall of the flat tube 7, thereby ensuring that there is no violent mixing and collision between the fluids when entering the container, thereby reducing the occurrence of bubbles during liquid separation.

[0018] For details, please refer to the attached manual Fig. 9 -Attached Fig.10 The inner side of the arc-shaped baffle plate 9 extends a distance toward the inner wall of the flat tube 7, and the surface of the arc-shaped baffle plate 9 is coated with a layer of hydrophobic layer material. The overall width of the flat tube 7 increases from top to bottom.

[0019] The specific implementation method is as follows: the arc-shaped baffle plate 9 is extended toward the inner wall of the flat tube 7 for a distance, so that the output fluid can be blocked and guided during use, and the fluid is drained to the outlet position of the flat tube 7 on one side close to the inner wall of the container, so that the solution is slowly guided into the container through the inner wall, thereby slowing down the output speed of the solution and avoiding the problem that the liquid directly impacts the bottom of the container wall vertically, causing a large amount of foam to be formed after a violent collision, thereby further improving the separation quality of the sample solution.

[0020] Working principle of the present invention: The first step: First, the operator assembles the various components of the device normally, and then uses the device normally to perform the automatic liquid dispensing process. The built-in micro-peristaltic pump structure controls the liquid dispensing structure 4 to perform micro-dispensing of the sample liquid. At the same time, during the dispensing, the flat tube 7 under the connecting hose 6 is tightly attached to the inner wall of one side of the container, forming a tightly attached state therewith.

[0021] Step 2: First, when the connecting hose 6 is controlled by the micro-peristaltic pump for infusion, when the liquid gradually flows into the flat tube 7 through the connecting hose 6, the liquid is gradually guided to the other side through the arc-shaped trajectories of section A and section B on one side of the inner wall of the flat tube 7. At the same time, the liquid is diffused and diverted outward along the inner wall of the flat tube 7 that expands outward in an involute shape, that is, the liquid is inclined and concentrated to one side of the flat tube 7, and diverted outward in a dispersed composite flow trajectory, and finally flows out from the arc-shaped outlet end at the bottom of the flat tube 7. At this time, the fluid will flow from the outlet of the flat tube 7 to the inner wall surface of the container in a fan-shaped posture, and slowly flow to the center of the container by adhering to its inner wall, which reduces the speed of the liquid flowing into the container on the one hand, It also increases the inflow area of ​​the liquid, thereby reducing the liquid surface pressure in the fluid input container. On the other hand, it avoids the situation where the liquid is vertically injected into the container from top to bottom, thereby avoiding the liquid from violently colliding and flowing with each other when it is continuously discharged, mixing a large amount of gas into it, and forming a layer of foam surface that is difficult to eliminate on the surface of the liquid, thereby affecting the quality of the sample. At the same time, when the liquid flows out of the output port of the flat tube 7, the inner curved surface 91 set below the output port can be used to guide the final output direction of the liquid, so that it flows toward the inside of the container, further increasing the controllability of the fluid movement direction. Finally, the device completes the drainage and buffering workflow when the sample solution is packaged.

[0022] Step 3: First, the operator shuts down the device normally, then checks whether the fixation between the various components of the device is normal, and then replaces and repairs the aging and severely worn parts inside the device.

[0023] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change; Secondly: In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other; Finally: The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A fully automatic micro-dispenser, comprising a device, wherein the inside of the device is electrically connected to an operation screen, a container rack is placed on the top surface of the device, a liquid dispensing structure is provided on the side of the device, and a fixed slide rail is provided on the top of the device and on one side of the liquid dispensing structure, characterized in that: The side of the liquid separation structure is connected with a plurality of connecting hoses, and the ends of the plurality of connecting hoses are fixed with flat tubes, one side of the flat tube is integrally formed with a recessed notch, and the flat tube as a whole is a flat duckbill structure, the cross section of the connection between the upper port of the flat tube and the connecting hose is circular, and the outlet shape of the lower port is arc-shaped, and the shape of the flat tube from top to bottom gradually expands outward in an involute shape, that is, the radius of the circular cross section of the top end of the flat tube is smaller than the radius value of the arc at the bottom end; The inner wall track formed by the recessed notch on the inner side of the flat tube is divided into two arc tracks, A and B, wherein the overall curvature of the A section is smaller than the overall curvature of the B section, and the overall length of the B section is larger than the overall length of the A section. A tangent is drawn on the outer side of the arc track of the B section, and the angle between the extended line of the tangent and the vertical inner wall of the other side of the flat tube is less than 90°; An arc-shaped baffle is fixedly installed on one side of the bottom end of the flat tube, and the arc-shaped baffle includes an inner arc-shaped surface, the bottom end of the inner arc-shaped surface is connected to the outer arc-shaped surface, and a notch is formed below the connection between the inner arc-shaped surface and the outer arc-shaped surface, the arc-shaped convex directions of the inner arc-shaped surface and the outer arc-shaped surface are oppositely distributed, and the inner arc-shaped surface and the outer arc-shaped surface are transitioned by a rounded shape, and the notch is located as a whole at an obliquely lower position of the inner arc-shaped surface.

2. A fully automatic micro-dispenser according to claim 1, characterized in that: The connecting hose is seamlessly connected to the flat tube, and both sides of the bottom outlet of the flat tube are respectively rounded.

3. A fully automatic micro-dispenser according to claim 1, characterized in that: The left and right sides of the arc-shaped baffle respectively extend to the bottom rounded corners of the flat tube.

4. A fully automatic micro-dispenser according to claim 1, characterized in that: The inner side of the arc-shaped baffle extends a distance toward the inner wall of the flat tube, and the surface of the arc-shaped baffle is coated with a layer of hydrophobic layer material.

5. A fully automatic micro-dispenser according to claim 1, characterized in that: The overall width of the flat tube increases from top to bottom.