Traditional Chinese medicine lotion for promoting perianal postoperative wound healing, preparation method and application

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine lotion for promoting perianal postoperative wound healing as well as a preparation method and application of the traditional Chinese medicine lotion. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 4-6 parts of rhizoma coptidis, 4-6 parts of fructus gardeniae, 4-6 parts of cortex phellodendri, 4-6 parts of radix scutellariae, 4-6 parts of raw radix et rhizoma rhei, 4-6 parts of dried alum, 4-6 parts of frankincense, 4-6 parts of myrrh, 4-6 parts of herba menthae, 4-6 parts of schizonepeta spike, 8-12 parts of radix sophorae flavescentis, 13-18 parts of radix arnebiae seu lithospermi, 4-6 parts of radix angelicae sinensis, 8-12 parts of flos lonicerae, 8-12 parts of flos chrysanthemi indici and 13-18 parts of rhizoma bletillae. The traditional Chinese medicine composition can obviously relieve postoperative pain of patients with mixed hemorrhoids, low-position anal fistula and perianal abscess, relieve edema, keep granulation healthy, reduce exudation, shorten healing time and promote wound healing, and has an obvious better technical effect.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine lotion for promoting wound healing after anal surgery, a preparation method and application thereof. Background Art

[0002] The healing time of perianal wounds after surgery is generally 2 to 8 weeks, and the specific time varies from individual to individual. In order to promote the healing of perianal wounds after surgery, patients can also use some drugs, such as hemorrhoid cream, moist burn cream, and muscle-growing cream, which can promote the healing of wounds. At the same time, local Chinese medicine sitz bath in the anus is also an effective way to promote wound healing.

[0003] Research progress on the treatment of postoperative pain of mixed hemorrhoids with external therapy of traditional Chinese medicine, Ye Ziyi, Yao Xiangyang, Peng Junliang, etc., Chinese Community Physician, 2023, 39(17): 4-6, believed that Western medicine treatment mainly treats postoperative pain symptomatically through intramuscular injection or oral analgesics, but there are drug toxicity and side effects, such as gastrointestinal reactions, damage to liver and kidney function, etc. In the treatment of anorectal diseases with external therapy of traditional Chinese medicine, whether it is postoperative complications of anorectal diseases, such as postoperative pain, postoperative incision edema, or conservative treatment of mixed hemorrhoids and other anorectal diseases, Chinese medicine fumigation and bathing are used for treatment, and the efficacy has been confirmed by clinical observation. In the treatment of traditional Chinese medicine characteristics, Chinese medicine fumigation and bathing therapy is a common external treatment method. Its principle is to use Chinese medicine ingredients and heat energy to directly act on the perianal lesions to restore local function, so as to achieve the effect of promoting postoperative healing and reducing postoperative complications of mixed hemorrhoids. It has the advantages of rapid onset, low cost and low toxicity and side effects.

[0004] Based on data mining, the use of traditional Chinese medicine fumigation and washing to treat postoperative pain in mixed hemorrhoids is discussed. Li Huiwen, Yan Jian, Chinese Medical Forum, 2024, 39(05): 18-21. DOI: 10.13913 / j.cnki.41-1110 / r.2024.05.019, based on data mining, the use of IBM SPSS Statistics 26 and other software to conduct statistics on the frequency of use of traditional Chinese medicine fumigation and washing to treat postoperative pain in mixed hemorrhoids is made public. The statistical results show that the top 8 drugs in terms of frequency of use are Phellodendron, Sophora flavescens, Schisandra chinensis, Sophora japonica, Rhubarb, Taraxacum officinale, Honeysuckle, Angelica dahurica, etc., and most of them are bitter and cold drugs.

[0005] Effect of fumigation therapy with Kushen decoction on wound healing and complications in patients with mixed hemorrhoid surgery, Chen Xiaoping, Xu Wenbin, Zhao Yun, Guizhou Medicine, 2022, 46(04): 609-610. A total of 80 patients with mixed hemorrhoid surgery were treated with Kushen decoction. At 2, 3, 5, and 7 days after surgery, the pain VAS score, wound healing time, anal distension disappearance time, and pain disappearance time of the observation group were lower than those of the control group (P<0.05).

[0006] Study on the effect of Huangbai Kushen decoction sitz bath fumigation combined with low incision and high hanging thread on postoperative pain in patients with anal fistula. Gao Quanxi, Gao Weiqi, Jiang Yaoyao, et al., Inner Mongolia University, publicly divided 72 patients with anal fistula who underwent low incision and high hanging thread into the surgery into a reference group and a study group. They were given potassium permanganate and Huangbai Kushen decoction sitz bath respectively after surgery. The study group was superior to the reference group in VAS score, wound healing, and serum factor levels.

[0007] The above technology can only relieve pain, reduce edema and promote healing for patients with mixed hemorrhoids after surgery. Its effect on promoting wound healing in patients with anal fistula and perianal abscess after surgery is unclear. Furthermore, there is still some room for improvement in the efficacy of traditional Chinese medicine sitz baths for patients after surgery for anorectal diseases. Summary of the invention

[0008] The technical problem to be solved by the present invention is to provide a traditional Chinese medicine lotion for promoting the healing of wounds after anal surgery, a preparation method and application thereof, so as to improve the effect of the healing of wounds after anal surgery.

[0009] The embodiment of the present invention discloses a traditional Chinese medicine lotion for promoting the healing of perianal postoperative wounds. The traditional Chinese medicine lotion comprises the following components by weight: 4-6 parts of coptis root, 4-6 parts of gardenia, 4-6 parts of phellodendron, 4-6 parts of scutellaria, 4-6 parts of raw rhubarb, 4-6 parts of alum, 4-6 parts of frankincense, 4-6 parts of myrrh, 4-6 parts of mint, 4-6 parts of schizonepeta spicate, 8-12 parts of sophora flavescens, 13-18 parts of lithospermum officinale, 4-6 parts of angelica sinensis, 8-12 parts of honeysuckle, 8-12 parts of wild chrysanthemum and 13-18 parts of bletilla striata.

[0010] Preferably, it comprises the following components by weight: 5 parts of Coptidis Rhizoma, 5 parts of Gardenia Fructus, 5 parts of Phellodendron Amurense, 5 parts of Scutellaria Baicalensis, 5 parts of Rhubarb, 5 parts of Alum, 5 parts of Frankincense, 5 parts of Myrrh, 5 parts of Menthus Fructus, 5 parts of Schizonepeta Spike, 10 parts of Sophora Flavescentis, 15 parts of Lithospermum Officinale, 5 parts of Angelica Sinensis, 10 parts of Honeysuckle, 10 parts of Chrysanthemum Indici, and 15 parts of Bletilla Striata.

[0011] The embodiment of the invention discloses a method for preparing the traditional Chinese medicine lotion, which comprises the following steps: mixing the components by weight, decocting with water, concentrating the filtrate, filtering, and obtaining the lotion.

[0012] Preferably, after filtering, sodium benzoate and water are added and mixed evenly to obtain the product.

[0013] Preferably, in the traditional Chinese medicine lotion, the weight concentration of sodium benzoate is 0.2-0.4%.

[0014] Preferably, after the weight components are mixed, 10 times the weight of water is added for the first decoction, and 8 times the weight of water is added for the filtration residue for decoction, and the filtrate is combined.

[0015] Preferably, the filtrate is concentrated to a clear paste having a relative density greater than or equal to 1.04 at room temperature.

[0016] The embodiment of the present invention discloses a Chinese medicine lotion or an application of the Chinese medicine lotion prepared by the preparation method. The Chinese medicine lotion is used to prepare a medicine for promoting the healing of wounds after perianal surgery.

[0017] The beneficial effects of the present invention are that the present invention has the effects of clearing away heat and detoxifying, dispelling wind and drying dampness, cooling blood and stopping bleeding, and reducing swelling and promoting tissue regeneration. Through the combined action of heat and pharmacology, the pores are opened, blood and lymphatic circulation are improved, and the nerve endings are stimulated to sense receptors. When treating anorectal diseases, it can directly act on the wound surface.

[0018] This Chinese medicine lotion includes coptis chinensis, gardenia, phellodendron, scutellaria baicalensis, raw rhubarb, alum, frankincense, myrrh, mint, schizonepeta spicate, sophora flavescens, lithospermum erythrorhizon, angelica, honeysuckle, wild chrysanthemum and bletilla striata. Coptis chinensis, gardenia, phellodendron chinensis, scutellaria baicalensis, raw rhubarb, sophora flavescens, lithospermum erythrorhizon, angelica, honeysuckle, wild chrysanthemum and white ginseng. Coptis chinensis, gardenia, phellodendron chinensis, scutellaria baicalensis, raw rhubarb, sophora flavescens, lithospermum erythrorhizon, angelica, honeysuckle, wild chrysanthemum and others all have the effects of clearing away heat and dampness, purging fire and detoxifying, and stopping bleeding. Frankincense and myrrh have the effect of activating blood circulation, can improve local microcirculation of the wound, and also have a certain effect in promoting healing.

[0019] Compared with the Chinese medicine lotion of comparative example 1, 8 Chinese medicinal materials are added, including mint, schizonepeta spicate, sophora flavescens, lithospermum officinale, angelica sinensis, honeysuckle, wild chrysanthemum and bletilla striata. Mint contains ingredients such as peppermint oil and menthol, which can play analgesic, anti-inflammatory and sedative effects by stimulating nerve endings; schizonepeta spicate contains volatile oil, the main components of which are dextromenthone, racemic menthone and a small amount of dextromenthone limonene, which have anti-allergic, sedative and cooling effects; sophora flavescens is bitter and cold, clears away heat and dries, and has the effects of clearing heat and dampness, killing insects and diuresis; lithospermum officinale is bitter and cold, and has the effects of clearing heat and cooling blood, promoting blood circulation and detoxifying, and removing rashes and spots, "Compendium of Materia Medica" It is said that it can "treat macules, pox, promote blood circulation and cool blood, and benefit the large intestine"; Angelica sinensis is good at promoting blood circulation and relieving pain, warming and dispersing cold stagnation, and can also replenish blood, which is very effective for patients with postoperative blood loss; Honeysuckle and wild chrysanthemum can clear away heat and detoxify, and are the main medicines for treating heat-toxic carbuncles, boils, and furuncles. They have antibacterial, antiviral, and anti-inflammatory effects. In addition, they can enhance the patient's immunity and promote the self-healing of the wound; Bletilla striata is a hemostatic medicine, which has the effects of astringent hemostasis, swelling and muscle regeneration, and external application can promote wound healing. The whole prescription has 16 herbs, and external sitz bath can relieve many postoperative discomforts of patients and promote the recovery of postoperative wounds.

[0020] Both Example 1 and Comparative Example 1 of the present invention use drugs with the effects of clearing away heat and dampness, promoting blood circulation, etc., but the inventors found that the drug of Example 1, compared with the drug of Comparative Example 1, can significantly relieve postoperative pain in patients with mixed hemorrhoids, low anal fistulas, and perianal abscesses, reduce edema, maintain healthy granulation tissue, reduce exudation, shorten healing time, and promote wound healing, and has significantly better technical effects. DETAILED DESCRIPTION

[0021] Example 1 A traditional Chinese medicine lotion for promoting wound healing after perianal surgery, comprising the following components by weight: 5g of Coptis chinensis, 5g of Gardenia jasminoides, 5g of Phellodendron chinense, 5g of Scutellaria baicalensis, 5g of Rhubarb, 5g of Alum, 5g of Frankincense, 5g of Myrrh, 5g of Menthus frankincense, 5g of Schizonepeta spicate, 10g of Sophora flavescens, 15g of Lithospermum officinale, 5g of Angelica sinensis, 10g of Honeysuckle, 10g of Chrysanthemum indicum, and 15g of Bletilla striata.

[0022] The preparation method of the Chinese medicine lotion is as follows: the above 16 herbs are decocted twice with water, decocted for 30 minutes with 10 times the amount of water for the first time and decocted for 30 minutes with 8 times the amount of water for the second time, the water extract is filtered, the filtrate is combined, concentrated to a clear paste with a relative density greater than or equal to 1.04 (25 degrees Celsius), filtered, 1.5g (0.3%) of sodium benzoate is added to the filtrate, water is added to 500ml, mixed evenly, and filled.

[0023] Comparative Example 1 A Chinese medicine lotion, comprising the following components by weight: 20g of Coptis chinensis, 15g of Gardenia jasminoides, 15g of Phellodendron chinense, 15g of Scutellaria baicalensis, 15g of Rhubarb, 10g of Alum, 10g of Frankincense, 10g of Myrrh, and 5g of Borneol.

[0024] The preparation method is the same as that of Example 1.

[0025] Example 2 Clinical trials and data: 1. Clinical data 1.1 Diagnostic criteria The diagnostic standards of Western medicine refer to the "Diagnosis and Treatment of Anorectal Diseases", and the diagnostic standards of traditional Chinese medicine refer to the "Guidelines for the Diagnosis and Treatment of Common Anorectal Diseases in China".

[0026] 1.2 Inclusion criteria (1) Patients who meet the above diagnostic criteria; (2) Aged between 18 and 70 years old, regardless of gender; (3) No severe organ dysfunction or surgical contraindications; (4) Those with no history of anal surgery and no obvious abnormalities in anal morphology and function were found during physical examination; (5) All patients participated voluntarily and signed informed consent.

[0027] 1.3 Exclusion criteria (1) Patients with other anorectal diseases and diseases that affect wound healing; (2) Patients with allergic constitution or those who are allergic to the drug ingredients contained in this study; (3) Patients who are pregnant, lactating or menstruating; (4) Alcohol and drug abusers; (5) Patients who are participating in other clinical trials.

[0028] 1.4 Falling off and rejection criteria (1) Those who experience serious adverse reactions during treatment; (2) Those who have used other treatments or drugs during the course of treatment and whose efficacy cannot be determined; (3) Those who fail to cooperate with relevant treatment; (4) Participants with incomplete data, lost to follow-up, or requesting to withdraw from the trial midway.

[0029] 1.5 General Information The study cases were from patients with mixed hemorrhoids, low simple anal fistula, and perianal abscess (subcutaneous) who were hospitalized for surgery at Beijing University of Chinese Medicine Shenzhen Hospital (Longgang) from January 2024 to August 2024. 60 patients were collected for each disease in this study and divided into an observation group and a control group according to the random number table method, with 30 cases in each group. Patients with mixed hemorrhoids underwent external stripping and internal ligation of mixed hemorrhoids by senior physicians under combined spinal-epidural anesthesia, patients with low simple anal fistula underwent anal fistula resection, and patients with perianal abscess underwent primary radical surgery.

[0030] There was no significant difference in the general data of the two groups of patients with the three diseases (P>0.05), which showed that they were comparable. See Tables 1, 2, and 3 for details.

[0031] Table 1 Comparison of general data of two groups of patients (mixed hemorrhoids)

[0032] Table 2 Comparison of general data of patients in the two groups (low anal fistula)

[0033] Table 3 Comparison of general data of patients in the two groups (perianal abscess)

[0034] 2. Treatment Methods 2.1 Control group On the first day after surgery, the Chinese medicine lotion of Comparative Example 1 was used for fumigation and sitting bath at 08:00:00.

[0035] 2.2 Observation Group On the first day after surgery, the Chinese medicine lotion of Example 1 was used for fumigation and sitting bath at 08:00:00.

[0036] Sitz bath method: Both groups of patients placed the Chinese herbal lotion prepared by our hospital in a suitable container, and used one bag (500ml / bag) each time to mix with 500ml of warm water, diluting it 1:1. While ensuring safety, the patients were advised to completely relax the perianal area, with the wound facing the liquid medicine, and use the hot steam to fumigate the perianal area. After washing several times with the liquid medicine, a sitz bath was performed, and the surgical site was thoroughly immersed in the Chinese herbal liquid for about 10 minutes / time. After the end, the liquid was wiped dry. The sitz bath was performed 3 times a day, with an interval of 4 hours each time. At the end of each treatment, routine dressing changes were performed.

[0037] 3. Observation indicators 3.1 Anal and perianal pain scores on days 1, 3, and 7 after surgery.

[0038] Perianal pain score: According to the VAS method and combined with the actual clinical situation, the score is as follows: 0 points for no pain; 2 points for mild or intermittent pain, which is still tolerable and does not affect sleep; 4 points for moderate pain, which affects sleep quality and can only be relieved by taking common analgesics such as levofloxacin; 6 points for severe pain, which seriously affects sleep and cannot be relieved without strong analgesics such as injection of morphine.

[0039] 3.2 Wound edema scores of patients with mixed hemorrhoids on days 1, 3, and 7 after surgery.

[0040] Wound edema score: 0 points indicate that the wound edge is smooth and without edema; 1 point indicates that the wound edge is slightly raised but still soft to the touch, and the edema range is less than one-quarter of the anal area; 2 points indicate that the wound edge is translucent, hardened, and red, ranging from 1 / 4 to 1 / 2 of the anal area; 3 points indicate local necrosis or mass, greater than 1 / 2 of the anal area.

[0041] 3.3 Granulation tissue and wound exudate scores before and after treatment in patients with low anal fistula and perianal abscess (1) Granulation tissue scoring: 0 points if the granulation tissue is ruddy and firm; 1 point if the granulation tissue is slightly white; 2 points if the granulation tissue is pale and accompanied by inflammatory granulation; 3 points if the granulation tissue is dark red, with local erosion and necrosis, and needs to be trimmed.

[0042] (2) Wound exudate score: 0 points if no exudate occurs 24 hours after surgery; 1 point if exudate penetrates 1 to 3 layers of gauze; 2 points if exudate penetrates 4 to 6 layers; and 3 points if exudate penetrates more than 6 layers.

[0043] 3.4 Wound healing time The time required for wound healing after surgery was compared between the two groups of patients.

[0044] 3.5 Adverse events During this trial, if the subjects experience allergic reactions such as skin itching, papules, erythema, blisters, or even general discomfort, they should stop taking the medication immediately, report to their superior physician immediately, take appropriate treatment measures, record the evolution and outcome of the symptoms truthfully, and record the results.

[0045] 4. Statistical methods SPSS 25.0 software was used to perform statistical analysis on the collected data. The measurement data were described as mean ± standard deviation and the t test was used. The count data were expressed as rate (%) and the χ2 test was used. P < 0.05 was considered statistically significant.

[0046] 3. Results 1. Comparison of patients' postoperative pain scores. The experimental results are shown in Tables 4-6.

[0047] The 1st, 3rd and 7th days after surgery were the most significant pain periods. For patients after mixed hemorrhoid surgery, the pain scores of the observation group were lower than those of the control group, and the difference was statistically significant (P<0.05); for patients after low anal fistula surgery, the pain scores of the observation group were lower than those of the control group, and the difference was statistically significant (P<0.05); for patients after perianal abscess surgery, the pain scores of the observation group were lower than those of the control group, and the difference was statistically significant (P<0.05), indicating that for patients after mixed hemorrhoid surgery, low anal fistula and perianal abscess surgery, the use of this Chinese medicine lotion for sitting bath can relieve the pain of patients, and the effect of this Chinese medicine lotion is better than that of hemorrhoids.

[0048] Table 4 Comparison of pain scores of patients 1, 3, and 7 days after surgery (mixed hemorrhoids)

[0049] Table 5 Comparison of pain scores of patients 1, 3, and 7 days after surgery (low anal fistula)

[0050] Table 6 Comparison of pain scores of patients 1, 3, and 7 days after surgery (perianal abscess)

[0051] 2. Comparison of patients' postoperative edema scores. The experimental results are shown in Table VII.

[0052] The incidence of edema is high due to obstruction of venous return after mixed hemorrhoid surgery. Low-position anal fistula and perianal abscess rarely have edema complications. Therefore, only the edema scores of patients with mixed hemorrhoids were observed. The edema scores of patients in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05), indicating that this Chinese medicine lotion is better than hemorrhoid dissipation in relieving postoperative wound edema in patients with mixed hemorrhoids.

[0053] Table 7 Comparison of edema scores of patients 1, 3, and 7 days after surgery (mixed hemorrhoids)

[0054] 3. Comparison of granulation tissue scores of patients before and after treatment. The experimental results are shown in Tables 8-9.

[0055] The wound surface of anal fistula and perianal abscess is larger than that of mixed hemorrhoids, and granulation tissue is prone to unhealthy morphology. Therefore, the granulation tissue scores of patients with low anal fistula and perianal abscess before and after treatment were mainly observed. There was no statistical difference between the two groups of patients after low anal fistula surgery before treatment (P>0.05). After treatment, the granulation tissue score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05); there was no statistical difference between the two groups of patients after perianal abscess surgery before treatment (P>0.05). After treatment, the granulation tissue score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05). The data showed that this Chinese medicine lotion was better than Zhixiaosan in maintaining the healthy morphology of granulation tissue.

[0056] Table 8 Comparison of granulation tissue scores of patients before and after treatment (low anal fistula)

[0057] Table 9 Comparison of granulation tissue scores of patients before and after treatment (perianal abscess)

[0058] 4. Comparison of exudation scores of patients before and after treatment. The experimental results are shown in Tables 10-11.

[0059] Mixed hemorrhoid patients rarely have exudation after surgery, so the exudation scores of patients with low anal fistula and perianal abscess before and after treatment were mainly observed. There was no statistical difference between the two groups of patients with low anal fistula before treatment (P>0.05). After treatment, the exudation score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05); there was no statistical difference between the two groups of patients with perianal abscess before treatment (P>0.05). After treatment, the exudation score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05). This shows that compared with Zhixiaosan, this Chinese medicine lotion can better reduce the exudation of the postoperative wound surface of patients.

[0060] Table 10 Comparison of exudation scores of patients before and after treatment (low anal fistula)

[0061] Table 11 Comparison of exudation scores of patients before and after treatment (perianal abscess)

[0062] 5. Comparison of wound healing time among patients. The experimental results are shown in Table 12.

[0063] The wound healing time of each disease observation group was shorter than that of the control group, and the difference was statistically significant (P<0.05), indicating that this Chinese medicine lotion is better than hemorrhoids in reducing healing time and promoting wound healing.

[0064] Table 12 Comparison of wound healing time

[0065] Based on the above data analysis, the Chinese medicine lotion of the present invention can significantly relieve postoperative pain, reduce edema, maintain healthy granulation tissue, reduce exudation, shorten healing time, and promote wound healing in patients with mixed hemorrhoids, low anal fistula, and perianal abscess, compared with the Chinese medicine lotion of comparative example 1, and the results are statistically significant (P<0.05).

[0066] A person skilled in the art should understand that the discussion of any of the above embodiments is merely illustrative and is not intended to imply that the scope of protection of the present application is limited to these examples. In line with the concept of the present application, the technical features in the above embodiments or different embodiments may be combined, the steps may be implemented in any order, and there are many other variations of different aspects of one or more embodiments of the present application as described above, which are not provided in detail for the sake of simplicity.

[0067] One or more embodiments of the present application are intended to cover all such substitutions, modifications and variations that fall within the broad scope of the present application. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of one or more embodiments of the present application should be included in the protection scope of the present application.

Claims

1. A Chinese medicine lotion for promoting wound healing after perianal surgery, characterized in that: The invention comprises the following components by weight: 4-6 parts of coptis root, 4-6 parts of gardenia, 4-6 parts of phellodendron, 4-6 parts of scutellaria, 4-6 parts of raw rhubarb, 4-6 parts of alum, 4-6 parts of frankincense, 4-6 parts of myrrh, 4-6 parts of mint, 4-6 parts of schizonepeta spicate, 8-12 parts of sophora flavescens, 13-18 parts of lithospermum officinale, 4-6 parts of angelica sinensis, 8-12 parts of honeysuckle, 8-12 parts of wild chrysanthemum and 13-18 parts of bletilla striata.

2. The Chinese medicine lotion according to claim 1, characterized in that: The invention comprises the following components by weight: 5 parts of coptis root, 5 parts of gardenia, 5 parts of phellodendron, 5 parts of scutellaria, 5 parts of raw rhubarb, 5 parts of alum, 5 parts of frankincense, 5 parts of myrrh, 5 parts of mint, 5 parts of schizonepeta spicate, 10 parts of sophora flavescens, 15 parts of lithospermum officinale, 5 parts of angelica sinensis, 10 parts of honeysuckle, 10 parts of wild chrysanthemum and 15 parts of bletilla striata.

3. A method for preparing the Chinese medicine lotion as claimed in claim 1 or 2, characterized in that: The weight components are mixed, boiled with water, and the filtrate is concentrated and filtered to obtain.

4. The preparation method according to claim 3, characterized in that: After filtering, add sodium benzoate and water and mix well to obtain.

5. The preparation method according to claim 4, characterized in that: In the traditional Chinese medicine lotion, the weight concentration of sodium benzoate is 0.2-0.4%.

6. The preparation method according to claim 3, characterized in that: After the weight components are mixed, 10 times the weight of water is added for the first decoction, and 8 times the weight of water is added for the filtration residue for decoction, and the filtrate is combined.

7. The preparation method according to claim 3, characterized in that: The filtrate is concentrated to a clear paste having a relative density greater than or equal to 1.04 at room temperature.

8. A use of the Chinese medicine lotion according to claim 1 or 2, or the Chinese medicine lotion prepared by the preparation method according to any one of claims 3 to 7, characterized in that: The traditional Chinese medicine lotion is used for preparing medicine for promoting the healing of wounds after perianal surgery.

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