Extracorporeal membrane oxygenation kit and use method thereof

Abstract

The invention provides an extracorporeal membrane oxygenation kit and a using method thereof.The extracorporeal membrane oxygenation kit comprises a pump head, an oxygenator and an extracorporeal circulation pipeline, the pump head is communicated with the oxygenator through the extracorporeal circulation pipeline, the extracorporeal circulation pipeline comprises a pipeline body and quick connectors, the two ends of the pipeline body are connected with the quick connectors, and the quick connectors are connected with the pump head. The pump head is communicated with one end of the pipeline through one quick connector, the oxygenator is communicated with the other end of the pipeline through the other quick connector, each quick connector comprises a female head and a male head, and the female head and the male head are connected in a clamped mode. According to the extracorporeal membrane oxygenation sleeve bag, the pump head, the oxygenator and the extracorporeal circulation pipeline are connected with one another through the quick connector, the quick connector is connected with the male connector in a clamped mode through the female connector for quick connection and disconnection, and therefore quick replacement can be conducted when thrombus appears in the extracorporeal membrane oxygenation sleeve bag.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an extracorporeal membrane oxygenation kit and a use method thereof. Background Art

[0002] Extracorporeal membrane oxygenation (ECMO) is an extracorporeal circulation support system that is mainly used to provide continuous extracorporeal respiratory and circulatory support to emergency and critically ill patients with cardiopulmonary failure to maintain their lives. The core components of ECMO include the host (main console) and consumables (extracorporeal membrane oxygenation circulation kit), and other devices include temperature-controlled water tanks, air-oxygen mixers, etc.

[0003] During the extracorporeal membrane oxygenation (ECMO) process, thrombosis may occur in the extracorporeal circulation circuit due to problems such as surgical intubation and insufficient anticoagulation management. After the thrombosis occurs, it will cause problems with blood circulation in the extracorporeal circulation circuit. Then it is necessary to replace the pump head, oxygenator assembly or the entire kit during the extracorporeal circulation process according to the location of the thrombus. In the prior art, when replacing the pump head or oxygenator assembly, it is necessary to stop the drive, clamp the upstream and downstream pipes of the assembly, cut the extracorporeal circulation pipes before and after the pump head or oxygenator, and connect the pipes to the new assembly. During this operation, the scissors will directly contact the extracorporeal circulating blood, and destroy the sterile state of the bag blood channel itself, introducing the risk of infection. Summary of the invention

[0004] The invention provides an extracorporeal membrane oxygenation kit and a method for using the same. The extracorporeal membrane oxygenation kit is used to solve the problems in the prior art that the sterile state of a blood channel itself may be destroyed when replacing components and the operation is complicated.

[0005] The present invention provides an extracorporeal membrane oxygenation kit, comprising: a pump head, an oxygenator and an extracorporeal circulation pipeline, wherein the pump head is connected to the oxygenator through the extracorporeal circulation pipeline, the extracorporeal circulation pipeline comprises a pipeline and a quick connector, both ends of the pipeline are connected with the quick connector, the pump head is connected to one end of the pipeline through one quick connector, the oxygenator is connected to the other end of the pipeline through another quick connector, the quick connector comprises a female head and a male head, and the female head is snap-connected with the male head.

[0006] According to an extracorporeal membrane oxygenation kit provided by the present invention, the female head includes a locking button and a female head tube wall, the locking button is penetrated through the female head tube wall and is connected to the female head tube wall so as to be relatively movably connected, the male head includes the male head tube wall and a limiting protrusion, the limiting protrusion is fixed to the outer side wall of the male head tube wall, and the locking button is used to abut against the limiting protrusion along the direction in which the male head is inserted into the female head after the male head is inserted into the female head.

[0007] According to an extracorporeal membrane oxygenation kit provided by the present invention, the locking button includes a limiting portion and a pressing portion, the limiting portion is penetrated through the tube wall of the female head, the pressing portion is connected to one end of the limiting portion away from the tube wall of the female head, and the pressing portion extends along the axial direction of the female head.

[0008] According to an extracorporeal membrane oxygenation kit provided by the present invention, the quick connector also includes a rotating body and an anti-unlocking ejector pin, the rotating body is sleeved on the outer wall of the female head and is relatively rotatably connected to the female head, the anti-unlocking ejector pin is connected to the rotating body, and the rotating body can drive the anti-unlocking ejector pin to rotate between the pressing portion and the female head tube wall so as to abut against the pressing portion.

[0009] According to an extracorporeal membrane oxygenation kit provided by the present invention, the extracorporeal membrane oxygenation kit further includes a pre-filling component, and the pre-filling component is connected to the pump head and the oxygenator respectively through the quick connector.

[0010] According to an extracorporeal membrane oxygenation kit provided by the present invention, the extracorporeal circulation pipeline further includes a plurality of monitoring probes, and the plurality of monitoring probes are all connected to the pipeline through the quick connector.

[0011] According to an extracorporeal membrane oxygenation kit provided by the present invention, the material of the pipeline includes PVC or TPU.

[0012] According to an extracorporeal membrane oxygenation kit provided by the present invention, both ends of the quick connector are provided with undercuts, and the quick connector is connected to the pipeline via the undercuts.

[0013] The present invention also provides a method for using an extracorporeal membrane oxygenation kit, comprising: Connect the outlet of the pump head to the pipeline through a quick connector, connect the inlet of the oxygenator to the same pipeline through a quick connector, and connect the outlet of the pump head to the inlet of the oxygenator; Connect the inlet of the pump head to a vascular cannula connected to the patient through a quick connector, and connect the outlet of the oxygenator to another vascular cannula connected to the patient through a quick connector; The pump head is fixed to the driving device and started to run.

[0014] According to a method for using an extracorporeal membrane oxygenation kit provided by the present invention, after connecting the other two pipelines to the patient, the method further comprises: Connect the inlet end pipeline of the pump head to the pre-filling assembly through a quick connector, and connect the outlet end pipeline of the oxygenator to the pre-filling assembly through a quick connector; Start the pre-filling component to pre-fill until the pipeline is filled with liquid; Disconnect the inlet end pipeline of the pump head from the pre-filling assembly through the quick connector, and disconnect the outlet end pipeline of the oxygenator from the pre-filling assembly through the quick connector; Connect the two end pipes of the pump head to the two end pipes of the oxygenator respectively, so that the pump head and the oxygenator form a circulation passage, and drive the pump head to make the liquid circulate between the pump head and the oxygenator; When the patient preparation is completed, the connection between the inlet end pipeline of the pump head and the outlet end pipeline of the oxygenator is disconnected through the quick connector, and the inlet of the pump head is connected to the vascular cannula connected to the patient, and the outlet of the oxygenator is connected to another vascular cannula connected to the patient.

[0015] The present invention provides an extracorporeal membrane oxygenation kit and a method for using the same. The extracorporeal membrane oxygenation kit includes a pump head, an oxygenator, and an extracorporeal circulation pipeline, wherein the pump head and the oxygenator are connected through a pipeline, so that blood can circulate between the pump head and the oxygenator. The pump head and the pipeline, as well as the oxygenator and the pipeline, are connected by a quick connector, and the quick connector includes a male and a female connection, which can be quickly disconnected by engaging the male and female heads. When a thrombus occurs and the pump head or oxygenator needs to be replaced, the male and female heads of the pump head and the pipeline are directly disassembled, and then replaced with new components, and then the male and female heads are aligned and connected. The quick connector provided in the present application can be quickly disconnected when components need to be replaced, avoiding infection of the pipeline caused by scissors when the pipeline is cut. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 Schematic diagram of the extracorporeal membrane oxygenation kit provided by the present invention.

[0018] Figure 2 It is a schematic diagram of the quick connector provided by the present invention.

[0019] Figure 3 It is a schematic diagram of the female connector provided by the present invention.

[0020] Figure 4 It is a schematic diagram of the male connector provided by the present invention.

[0021] Figure 5 It is a cross-sectional view of the quick connector provided by the present invention.

[0022] Figure 6It is a schematic diagram of the locking state of the anti-unlocking ejector pin provided by the present invention.

[0023] Figure 7 It is a schematic diagram of the unlocking rotation state of the anti-unlocking ejector pin provided by the present invention.

[0024] Figure 8 It is a schematic diagram of the monitoring probe provided by the present invention.

[0025] Reference numerals: 1. Pump head; 2. Oxygenator; 3. Extracorporeal circulation pipeline; 31. Pipeline; 32. Quick connector; 321. Female connector; 322. Male connector; 323. Locking button; 3231. Limiting part; 3232. Pressing part; 324. Locking slot; 325. Undercut part; 33. Monitoring probe; 333. Monitoring assembly; 334. Data interface; 335. Undercut part; 34. Rotating body; 35. Anti-unlocking ejector pin; 36. Sealing ring; 4. Pre-filling assembly; 41. Pre-filling bag; 42. Liquid injection pipeline; 43. Pre-filling pipeline; 5. Elastic parts; 6. Display. DETAILED DESCRIPTION

[0026] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the drawings of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0027] Combine the following Figure 1 An extracorporeal membrane oxygenation kit of the present invention is described, comprising: a pump head 1, an oxygenator 2 and an extracorporeal circulation pipeline 3, the pump head 1 is connected to the oxygenator 2 through the extracorporeal circulation pipeline 3, the extracorporeal circulation pipeline 3 comprises a pipeline 31 and a quick connector 32, both ends of the pipeline 31 are connected with the quick connector 32, the pump head 1 is connected to one end of the pipeline 31 through a quick connector 32, the oxygenator 2 is connected to the other end of the pipeline 31 through another quick connector 32, the quick connector 32 comprises a female head 321 and a male head 322, and the female head 321 is snap-connected with the male head 322.

[0028] Please refer to Figures 1 to 4The extracorporeal membrane oxygenation kit includes a pump head 1, which can provide blood with circulation power during the extracorporeal circulation of blood. The oxygenator 2 is the main component of the extracorporeal membrane oxygenation. When the blood flows through the oxygenator 2, the blood is oxygenated and carbon dioxide is removed by the oxygenator 2. Therefore, the pump head 1 needs to be connected to the oxygenator 2.

[0029] Preferably, the oxygenator 2 should at least have a gas exchange fiber, a heat exchange fiber, a blood inlet and outlet, a water inlet and outlet, and a gas inlet and outlet. Among them, the blood inlet and outlet are connected to the extracorporeal circulation pipeline 3, the water inlet and outlet are connected to the heat exchange device, and the gas inlet is connected to the oxygen source. Extracorporeal circulating blood passes through the blood channel, is oxygenated and carbon dioxide is removed through the gas exchange fiber; heat exchange is performed through the heat exchange fiber to prevent heat loss of extracorporeal circulating blood. A side hole joint interface is configured at the blood inlet and outlet, and its side hole is used in combination with CRRT when clinically needed.

[0030] Preferably, the oxygenator 2 is designed in a square shape, with a fiber stacking angle of 90°, a gas exchange area composed of a gas exchange fiber mat, and a heat exchange area composed of a gas exchange fiber mat and a heat exchange fiber mat stacked together. Blood oxygenation and carbon dioxide removal are mainly achieved through the porous structure of the gas exchange fibers, and blood temperature is maintained through heat conduction of the heat exchange fibers.

[0031] In this embodiment, the connection is made through the extracorporeal circulation pipeline 3. Because blood needs to be able to circulate, the extracorporeal circulation pipeline 3 includes a pipeline 31. The outlet of the pump head 1 is connected to one end of the pipeline 31, and then the other end of the pipeline 31 is connected to the inlet of the oxygenator 2, and then blood can flow from the pump head 1 to the oxygenator 2. Then, the inlet of the pump head 1 is connected to the patient, and the outlet of the oxygenator 2 is connected to the patient, and the process of extracorporeal membrane oxygenation can be carried out.

[0032] During the process of extracorporeal membrane oxygenation, thrombus may occur in the circulation loop, resulting in obstruction of blood flow in the circulation loop. When thrombus occurs, it is usually observed on the pump head 1 and the oxygenator 2. Then it is necessary to replace the part where the thrombus occurs to remove the thrombus. Therefore, the present embodiment also includes a quick connector 32, and the pump head 1 and the oxygenator 2 are connected to the pipeline 31 through the quick connector 32. When thrombus occurs, it is only necessary to disassemble the male head 322 and the female head 321 of the quick connector 32 to disconnect the connection for replacement. For example, when thrombus blockage occurs in the pump head 1, the male head 322 and the female head 321 between the pump head 1 and the pipeline 31 are disassembled, and then the pump head 1 is replaced. After replacement, the pump head 1 without thrombus is connected to the pipeline 31 through the quick connector 32. The whole operation process is simple and convenient, and there is no need to cut the pipeline 31, and the sterile environment inside the pipeline 31 will not be destroyed, thus avoiding the risk of infection.

[0033] Specifically, the quick connector 32 includes a female head 321 and a male head 322, and the pump head 1 is connected to the pipeline 31 through the female head 321 and the male head 322. Among them, one of the female head 321 or the male head 322 is arranged on the pump head 1, and the other is arranged on the pipeline 31. In this embodiment, it is taken as an example that the female head 321 is arranged on the pump head 1 and the male head 322 is arranged on the pipeline 31. In different embodiments, the positions of the female head 321 and the male head 322 can also be exchanged, which is not limited here.

[0034] After the female connector 321 is connected to the pump head 1, align the female connector 321 on the pump head 1 with the male connector 322 on the pipeline 31. Because the female connector 321 and the male connector 322 are snap-fitted to each other, after the female connector 321 on the pump head 1 and the male connector 322 on the pipeline 31 are aligned with each other, insert the male connector 322 into the female connector 321 and snap the male connector 322 to ensure a firm connection between the male connector 322 and the female connector 321. After the pump head 1 is connected to the pipeline 31 through the female connector 321 and the male connector 322, ensure that the connection between the female connector 321 and the male connector 322 is sealed, so that blood can flow smoothly from the pump head 1 into the pipeline 31 without leakage. Similarly, in the same way, connect the oxygenator 2 to the pipeline 31, and connect the entire device to the patient through the quick connector 32, so that the extracorporeal membrane oxygenation operation can be performed.

[0035] Please refer to Figure 4 and Figure 5 A sealing ring 36 is sleeved on the front end of the male connector 322 inserted into the female connector 321. Because the outer diameter of this part of the male connector 322 corresponds to the inner diameter of the female connector 321, the outer wall of the male connector 322 will fit the inner wall of the female connector 321. Therefore, after the male connector 322 carrying the sealing ring 36 is inserted into the female connector 321, the sealing ring 36 is clamped between the outer wall of the male connector 322 and the inner wall of the female connector 321, thereby performing sealing.

[0036] During the process of extracorporeal membrane oxygenation, if a thrombus appears in the pump head 1, the connection between the female head 321 and the male head 322 of the quick connector 32 at both ends of the pump head 1 can be disconnected. Because the female head 321 and the male head 322 are snap-connected, the connection between the female head 321 and the male head 322 can be disconnected by disconnecting the snap-connection between the female head 321 and the male head 322. Then, the male head 322 is taken out from the female head 321 to disconnect the connection between the pump head 1 and the pipeline 31, and the pump head 1 can be replaced. The entire operation process only requires canceling the snap position of the male head 322, and then taking out the male head 322, which is simple and convenient to operate. Similarly, when a thrombus appears inside the oxygenator 2 or other components, the connection can be disconnected in the same way and then replaced, which will not be repeated here.

[0037] In the present application, the female head 321 and the male head 322 are engaged with each other to realize quick disconnection between the various components, so that when thrombosis occurs, the replacement of the various components is more convenient and quick, and the risk of infection can be avoided.

[0038] In one embodiment, the female head 321 includes a locking button 323 and a female head tube wall, the locking button 323 is penetrated through the female head tube wall and is connected to the female head tube wall so as to be relatively movably connected, the male head 322 includes a male head tube wall and a limiting protrusion 324, the limiting protrusion 324 is fixed to the outer wall of the male head tube wall, and the locking button 323 is used to abut against the limiting protrusion 324 along the direction of the male head 322 being inserted into the female head 321 after the male head 322 is inserted into the female head 321.

[0039] Please refer to Figures 2 to 5 Because the male head 322 needs to be inserted into the female head 321 to connect with the female head 321, the inner diameter of the female head 321 corresponds to the outer diameter of the male head 322. In order to control the insertion distance of the male head 322, a protrusion can be set in the female head 321, that is, the inner diameter of the female head 321 changes along the axial direction. Along the axial direction of the female head 321, the inner diameter of the part of the female head 321 close to the male head 322 corresponds to the outer diameter of the male head 322, so that the male head 322 can be inserted into the female head 321 and fit with the inner wall of the female head 321; and there is another part of the female head 321 whose inner diameter is smaller than the outer diameter of the male head 322, so that the male head 322 abuts against this part.

[0040] When the male head 322 is inserted into the female head 321 and abuts against the inner wall of the female head 321, the inner wall of the female head 321 limits the movement of the male head 322 toward the female head 321 and the radial movement of the male head 322. Therefore, at this time, the movement of the male head 322 away from the female head 321 is limited to prevent the male head 322 from slipping out of the female head 321.

[0041] Therefore, in this embodiment, the female head 321 further includes a locking button 323 and a female head tube wall. The locking button 323 is disposed through the female head tube wall and is relatively movably connected to the female head tube wall, so the locking button 323 can move relative to the female head 321 along the radial direction of the female head 321. At the same time, a limiting protrusion 324 is provided on the outer side of the male head tube wall of the male head 322, so the inner diameter at the entrance of the female head 321 needs to be increased so that the limiting protrusion 324 on the male head 322 can also enter the female head 321.

[0042] After the male head 322 with the limiting protrusion 324 is inserted into the female head 321, the male head 322 abuts against the inner wall of the female head 321. At this time, the male head 322 is limited by the abutment and cannot continue to move into the female head 321. Then the locking button 323 is moved in the direction toward the inside of the female head 321 until the locking button 323 moves to a position closer to the outer wall of the male head 322 than the top of the limiting protrusion 324. Because the locking button 323 abuts against the limiting protrusion 324 along the direction in which the male head 322 is inserted into the female head 321, the locking button 323 is located behind the limiting protrusion 324 and abuts against the limiting protrusion 324 along the direction in which the male head 322 is inserted into the female head 321. At this time, if the male head 322 needs to slide backward from the female head 321, it will be restricted by the locking button 323 and cannot move. The movement of the male head 322 toward the inside of the female head 321 is abutted by the inner wall of the female head 321 and cannot move. Thus, the limit stability after the male head 322 and the female head 321 are connected is guaranteed.

[0043] When a thrombus occurs and the connection needs to be disconnected, the operation is also very simple. It is only necessary to move the locking button 323 in a direction away from the inside of the female head 321 until the bottom of the locking button 323 is located above the top of the limiting protrusion 324. At this time, along the axis direction of the female head 321, the locking button 323 will not restrict the limiting protrusion 324, so that the male head 322 can slide out from the inside of the female head 321.

[0044] In this embodiment, by operating the locking button 323 to move toward or away from the inside of the female connector 321 , the male connector 322 can be locked or unlocked, thereby realizing the quick disconnection function of the quick connector 32 .

[0045] Specifically, the present embodiment provides a method of engaging and connecting the male head 322 and the female head 321 by means of a locking button 323. However, it is not limited thereto. In different embodiments, the male head 322 and the female head 321 may be engaged and connected by means of a buckle, a knob lock, etc., which can also make the connection or disconnection of the male head 322 and the female head 321 convenient and quick. For example, by means of a buckle, it is only necessary to connect the buckle with a pin on one of the male head 322 or the female head 321, and then provide a slot at a corresponding position on the other. When connection is required, the buckle is inserted into the slot, and the male head 322 and the female head 321 can be engaged and connected.

[0046] Please note that the locking method between the locking button 323 and the limiting protrusion 324 in the above description is only one of many implementation methods. The locking button 323 moves in the direction toward the inside of the female head 321 to achieve locking, and vice versa to unlock. This embodiment is not shown in the figure. Figure 5 As shown, another embodiment is provided. Figure 5In the illustrated embodiment, the locking button 323 is unlocked when it is moved in a direction toward the inside of the female head 321 , and is locked when it is moved in a direction toward the inside of the female head 321 . For specific implementation methods, please refer to the description of the following embodiment.

[0047] In one embodiment, the locking button 323 includes a limiting portion 3231 and a pressing portion 3232. The limiting portion 3231 is disposed through the tube wall of the female head 321. The pressing portion 3232 is connected to one end of the limiting portion 3231 away from the tube wall of the female head 321, and the pressing portion 3232 extends along the axial direction of the female head 321. In one embodiment, the quick connector 32 also includes a rotating body 34 and an anti-unlocking ejector pin 35. The rotating body 34 is sleeved on the outer wall of the female head 321 and is relatively rotatably connected to the female head 321. The anti-unlocking ejector pin 35 is connected to the rotating body 34. The rotating body 34 can drive the anti-unlocking ejector pin 35 to rotate between the pressing portion 3232 and the tube wall of the female head so as to abut against the pressing portion 3232.

[0048] Please refer to Figures 2 to 7 In this embodiment, the locking button 323 is approximately "L" shaped. The portion of the locking button 323 extending radially along the female head 321 is the limiting portion 3231, and the portion extending axially along the female head 321 is the pressing portion 3232. The limiting portion 3231 is extended radially along the female head 321 and is penetrated on the wall surface of the female head 321, and the pressing portion 3232 is connected to the limiting portion 3231. The surface area of ​​the pressing portion 3232 is large, thereby providing a larger contact area, so that the pressure when pressing the locking button 323 is reduced. The pressing portion 3232 is fixedly connected to the limiting portion 3231 to maintain synchronous movement.

[0049] like Figure 5 As shown, in this embodiment, the limiting portion 3231 of the locking button 323 is a protrusion at the bottom of the female head 321, and the pressing portion 3232 is located at the top of the female head 321, that is, the female head tube wall is located between the limiting portion 3231 and the pressing portion 3232. Therefore, in this embodiment, when the pressing portion 3232 is driven to move toward the female head 321, the pressing portion 3232 will drive the limiting portion 3231 to move in a direction away from the female head 321, thereby unlocking. When the pressing portion 3232 is driven to move away from the female head 321, the pressing portion 3232 will drive the limiting portion 3231 to move in a direction toward the female head 321, thereby locking. That is, according to Figure 5In the direction of the middle, when the pressing part 3232 drives the limiting part 3231 to move downward, the limiting part 3231 located at the bottom of the female tube wall moves downward away from the female tube wall, thereby unlocking the male head 322 in the female tube wall. Moreover, the distance between the limiting part 3231 at the top of the female tube wall and the male head 322 in the female tube wall is relatively large. After the limiting part 3231 at the top of the female tube wall moves downward, it will not limit the male head 322 in the female tube wall. Then, when the pressing part 3232 drives the limiting part 3231 to move upward, the limiting part 3231 located at the bottom of the female tube wall moves upward close to the inside of the female tube wall, thereby locking the male head 322 in the female tube wall.

[0050] Please refer to Figure 6 and Figure 7 , a rotating body 34 is sleeved on the female head 321, and an anti-unlocking ejector pin 35 extending radially along the female head 321 is connected to the rotating body 34. The rotating body 34 can rotate around the axis of the female head 321, and the anti-unlocking ejector pin 35 rotates together with the rotating body 34. When the male head 322 is connected to the female head 321, the rotating body 34 drives the anti-unlocking ejector pin 35 to rotate to the bottom of the pressing part 3232, that is, the anti-unlocking ejector pin 35 is located between the pressing part 3232 and the female head tube wall, and the anti-unlocking ejector pin 35 abuts against the pressing part 3232. Because the pressing portion 3232 needs to drive the limiting portion 3231 to move radially toward the inside of the female head 321 to be unlocked, and the anti-unlocking ejector pin 35 is located between the pressing portion 3232 and the outer wall of the female head 321, and the anti-unlocking ejector pin 35 extends radially and abuts against the pressing portion 3232, the anti-unlocking ejector pin 35 will abut against the pressing portion 3232 at this time, so that the pressing portion 3232 cannot move radially toward the female head 321, so that the locking button 323 is fixed in a locked state, thereby preventing the locking button 323 from being unlocked.

[0051] In this embodiment, the pressing portion 3232 moves radially toward the female head 321 for unlocking, and the anti-unlocking ejector pin 35 can prevent the pressing portion 3232 from performing this action, that is, the anti-unlocking ejector pin 35 can prevent unlocking. When the male head 322 is connected to the female head 321, the anti-unlocking ejector pin 35 prevents unlocking by abutting against it, which can avoid unlocking caused by misoperation and improve the stability of the connection. Similarly, when unlocking is required, the rotating body 34 is driven to drive the anti-unlocking ejector pin 35 to rotate, so that the anti-unlocking ejector pin 35 deviates from the bottom of the pressing portion 3232.

[0052] For further information, please refer to Figures 5 to 7, this embodiment also includes an elastic member 5. The elastic member 5 is also disposed between the pressing portion 3232 and the wall of the female tube, and the elastic member 5 is fixedly mounted on the wall of the female tube. When the pressing portion 3232 is pressed downward by pressure, because the elastic member 5 is elastic, the pressing portion 3232 presses down the elastic member 5, driving the elastic member 5 to move downward together. When the pressing portion 3232 is not subjected to pressure, the elastic member 5 drives the pressing portion 3232 to move upward by its own elastic force. Because in this embodiment, the pressing portion 3232 is subjected to pressure and moves downward to unlock, and the pressing portion 3232 moves upward to lock, so the elastic member 5 can automatically drive the pressing portion 3232 back to the locked state.

[0053] In one embodiment, the extracorporeal membrane oxygenation kit further includes a pre-filling component 4, which is respectively connected to the pump head 1 and the oxygenator 2 through a quick connector 32. In one embodiment, the extracorporeal circulation pipeline 3 further includes a plurality of monitoring probes 33, and the plurality of monitoring probes 33 are connected to the pipeline 31 through a quick connector 32. In one embodiment, the material of the pipeline 31 includes PVC or TPU.

[0054] Please refer to Figure 1 The extracorporeal membrane oxygenation kit provided by the present invention also includes a pre-filling component 4. Because before the extracorporeal membrane oxygenation circulation kit is connected to the patient, pre-filling and perfusion are required. Through pre-filling, it can be ensured that there is sufficient fluid in the system before the start of extracorporeal circulation, the air in the system is removed, the risk of bubble formation is reduced, bubbles are prevented from entering the patient's body, and bubble embolism is prevented; and the pre-filled system can ensure smooth startup after installation and maintain stable blood flow and oxygenation status. In the prior art, it is usually performed by opening a small hole in the main pipe, and pre-filling is performed through a pre-filling device connected in parallel with the small hole. After the pre-filling is completed, the small hole is sealed. However, such a pre-filling method will result in too small a flow rate and take too long.

[0055] In this embodiment, the pre-filling component 4 is also connected through the quick connector 32. The pre-filling component 4 includes a pre-filling bag 41, an injection pipeline 42 and a pre-filling pipeline 43. There are two pre-filling pipelines 43, one of which is connected to the pump head 1, and the other pre-filling pipeline 43 is connected to the oxygenator 2, and the pump head 1 is connected to the oxygenator 2, so as to form a circulation passage. Because the two pre-filling pipelines 43 are connected to the pump head 1 and the oxygenator 2 through the quick connector 32, the connection or disconnection of the pre-filling component 4 with the pump head 1 and the oxygenator 2 is very simple and convenient. Then the pre-filling component 4 can be directly connected to the pipeline 31, so as to increase the flow rate and shorten the pre-filling time. When the pre-filling is completed, the connection is directly disconnected through the quick connector 32 to realize the self-circulation of the main pipeline, which is convenient and quick to connect to the patient.

[0056] Furthermore, since the quick connector 32 is easy to connect, multiple monitoring probes 33 can be provided. Figure 1As shown, in this embodiment, three monitoring probes 33 are taken as an example, one is set before the inlet of the pump head 1, one is set after the outlet of the pump head 1, and one is set after the outlet of the oxygenator 2, thereby covering the three connecting pipelines of the entire device. In order to improve the accuracy of monitoring, the number of monitoring probes 33 can also be appropriately increased, or in order to save resources, the number of monitoring probes 33 can be reduced. Multiple monitoring probes 33 are installed and connected through quick connectors 32, and can also be quickly replaced when damaged, thereby avoiding adverse effects on the extracorporeal membrane oxygenation process.

[0057] like Figure 8 As shown, the monitoring probe 33 sensor assembly 333 and the data interface 334. One end of the monitoring probe 33 is connected to the male connector 322, and the other end is connected to the female connector 321, so that the monitoring probe 33 can be quickly disconnected. Then the sensor assembly 333 is used to detect blood data, and then transmit it through the data interface 334. In this embodiment, a display 6 is also included. The display 6 is composed of a screen and a cable. The screen has buttons, and the cable can be adapted to connect to the data interface 334, so as to display the blood data detected by the sensor assembly 333.

[0058] At the same time, in this embodiment, the material of the pipeline 31 is set to PVC or TPU. Because the monitoring probe 33 monitors the blood in the pipeline 31 by emitting a light signal, after the material of the pipeline 31 is set to PVC or TPU, the light signal emitted by the monitoring probe 33 can penetrate the pipeline 31, so that the monitoring probe 33 can be set to be non-invasive. Compared with invasive monitoring devices, the non-invasive type in this embodiment can avoid affecting the blood in the pipeline 31 and improve the efficiency of extracorporeal membrane oxygenation.

[0059] In one embodiment, both ends of the quick connector 32 are provided with undercut portions 325 , and the quick connector 32 is connected to the pipeline 31 via the undercut portions 325 .

[0060] Please refer to Figures 2 to 5 In this embodiment, both ends of the quick connector 32 need to be connected to the pipeline 31. Therefore, after the undercuts 325 are provided at both ends of the quick connector 32, the quick connector 32 is connected to the pipeline 31 through the undercuts 325. Because the undercuts 325 at both ends are inclined toward the middle, when the undercuts 325 are inserted into the pipeline 31 for connection, they follow the inclined direction of the undercuts 325, so they can enter the pipeline 31. When the quick connector 32 slides out of the pipeline 31, it goes against the inclined direction of the undercuts 325, so the undercuts 325 will get stuck on the inner wall of the pipeline 31, thereby preventing the quick connector 32 from sliding out of the pipeline 31.

[0061] In this embodiment, undercut portions 325 are provided at both ends of the quick connector 32 , thereby improving the stability of the connection between the quick connector 32 and the pipeline 31 .

[0062] The present invention also provides a method for using an extracorporeal membrane oxygenation kit, comprising: The outlet of the pump head 1 is connected to the pipeline 31 through the quick connector 32, and the inlet of the oxygenator 2 is connected to the same pipeline 31 through the quick connector 32, so that the outlet of the pump head 1 is connected to the inlet of the oxygenator 2; The inlet of the pump head 1 is connected to a vascular cannula connected to the patient through the quick connector 32, and the outlet of the oxygenator 2 is connected to another vascular cannula connected to the patient through the quick connector 32; The pump head 1 is fixed to the driving device and starts running.

[0063] Because the quick connector 32 can achieve quick disconnection and improve the efficiency of parts replacement, all the components in the present application are connected through the quick connector 32. The extracorporeal membrane oxygenation kit includes two main components, the pump head 1 and the oxygenator 2, so the pump head 1 and the oxygenator 2 are first connected to each other through the pipeline 31. The quick connector 32 is used at the connection point to ensure quick disconnection.

[0064] When the outlet of the pump head 1 is connected to the oxygenator 2 through the pipeline 31, blood can flow from the pump head 1 into the oxygenator 2. Then the inlet of the pump head 1 is connected to the patient, and the outlet of the oxygenator 2 is connected to the patient, so that a circulation loop is formed and the operation can begin.

[0065] However, because the initial pipeline 31 is full of air, in order to prevent air from entering the patient's body and affecting the patient, the pipeline 31 needs to be pre-filled before starting work. Then, the interfaces originally connected to the patient are connected to the pre-filling component 4 through the quick connector 32, and the pipeline 31 is pre-filled with liquid through the pre-filling component 4. The pre-filling component 4 includes a pre-filling bag 41, a liquid injection pipeline 42, and a pre-filling pipeline 43.

[0066] Preferably, the material of the pre-fill bag 41 is EVA, which is used to store common pre-fill solutions such as physiological saline and glucose solution; the inner diameter × wall thickness of the injection pipeline 42 is 1 / 4 inch × 1 / 16 inch, and it is equipped with a standard bottle stopper puncture device for transferring the pre-fill solution into the pre-fill bag 41; the material, inner diameter and wall thickness of the pre-fill pipeline 43 are consistent with those of the pipeline 31; the end of the pre-fill pipeline 43 is connected to the pipeline 31 through a quick connector 32, which can perform large-flow rapid pre-filling.

[0067] After the pre-filling is completed through the pre-filling component 4, the pump head 1 and the oxygenator 2 can be quickly disconnected through the quick connector 32, and the pump head 1 and the oxygenator 2 can be removed from the pre-filling component 4 and connected to the patient, so as to perform normal work and avoid the influence of air in the pipeline 31.

[0068] Further, after the pump head 1 is disconnected from the pre-filling component 4 through the quick connector 32, and the oxygenator 2 is disconnected from the pre-filling component 4 through the quick connector 32, the method further includes: The two ends of the pump head 1 are connected to the two ends of the oxygenator 2 respectively, so that the pump head 1 and the oxygenator 2 form a circulation passage, and the pump head 1 is started to make the liquid circulate between the pump head 1 and the oxygenator 2.

[0069] Therefore, in this embodiment, after the priming is completed, the connection with the priming assembly 4 is disconnected. Then, the outlet of the pump head 1 is connected to the inlet of the oxygenator 2, and then the outlet of the oxygenator 2 is connected to the inlet of the pump head 1, so that the pump head 1 and the oxygenator 2 form a circulation path, so that the priming solution circulates between the pump head 1 and the oxygenator 2, thereby avoiding long-term exposure to the air and contamination by pathogens.

[0070] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. An extracorporeal membrane oxygenation kit, characterized in that: include: A pump head (1), an oxygenator (2) and an extracorporeal circulation pipeline (3), wherein the pump head (1) is connected to the oxygenator (2) via the extracorporeal circulation pipeline (3), the extracorporeal circulation pipeline (3) comprising a pipeline (31) and a quick connector (32), both ends of the pipeline (31) being connected to the quick connector (32), the pump head (1) being connected to one end of the pipeline (31) via one quick connector (32), the oxygenator (2) being connected to the other end of the pipeline (31) via another quick connector (32), the quick connector (32) comprising a female connector (321) and a male connector (322), the female connector (321) being snap-fitted to the male connector (322).

2. The extracorporeal membrane oxygenation kit according to claim 1, characterized in that: The female head (321) comprises a locking button (323) and a female head tube wall, wherein the locking button (323) is penetrated through the female head tube wall and is connected to the female head tube wall in a relatively movably manner, and the male head (322) comprises the male head tube wall and a limiting protrusion (324), wherein the limiting protrusion (324) is fixed to the outer side wall of the male head tube wall, and the locking button (323) is used to abut against the limiting protrusion (324) along the direction in which the male head (322) is inserted into the female head (321) after the male head (322) is inserted into the female head (321).

3. The extracorporeal membrane oxygenation kit according to claim 2, characterized in that: The locking button (323) comprises a limiting portion (3231) and a pressing portion (3232), wherein the limiting portion (3231) is penetrated through the tube wall of the female head (321), and the pressing portion (3232) is connected to an end of the limiting portion (3231) away from the tube wall of the female head (321), and the pressing portion (3232) extends along the axial direction of the female head (321).

4. The extracorporeal membrane oxygenation kit according to claim 3, characterized in that: The quick connector (32) further comprises a rotating body (34) and an anti-unlocking ejector pin (35); the rotating body (34) is sleeved on the outer wall of the female head (321) and is connected to the female head (321) so as to be relatively rotatable; the anti-unlocking ejector pin (35) is connected to the rotating body (34); the rotating body (34) can drive the anti-unlocking ejector pin (35) to rotate between the pressing portion (3232) and the female head tube wall so as to abut against the pressing portion (3232).

5. The extracorporeal membrane oxygenation kit according to claim 1, characterized in that: The extracorporeal membrane oxygenation kit further comprises a pre-filling component (4), wherein the pre-filling component (4) is respectively connected to the pump head (1) and the oxygenator (2) via the quick connector (32).

6. The extracorporeal membrane oxygenation kit according to claim 1, characterized in that: The extracorporeal circulation pipeline (3) further comprises a plurality of monitoring probes (33), and the plurality of monitoring probes (33) are all connected to the pipeline (31) via the quick connector (32).

7. The extracorporeal membrane oxygenation kit according to claim 1, characterized in that: The material of the pipeline (31) includes PVC or TPU.

8. The extracorporeal membrane oxygenation kit according to claim 1, characterized in that: Both ends of the quick connector (32) are provided with undercut portions (325), and the quick connector (32) is connected to the pipeline (31) via the undercut portions (325).

9. A method for using an extracorporeal membrane oxygenation kit, characterized in that: include: The outlet of the pump head (1) is connected to the pipeline (31) through the quick connector (32), and the inlet of the oxygenator (2) is connected to the same pipeline (31) through the quick connector (32), so that the outlet of the pump head (1) is connected to the inlet of the oxygenator (2); The inlet of the pump head (1) is connected to a vascular cannula connected to the patient via a quick connector (32), and the outlet of the oxygenator (2) is connected to another vascular cannula connected to the patient via a quick connector (32); The pump head (1) is fixed to the drive device and started to run.

10. The method for using the extracorporeal membrane oxygenation kit according to claim 9, characterized in that: After the other two tubes (31) are connected to the patient, the following are also included: The inlet end pipeline (31) of the pump head (1) is connected to the pre-filling component (4) through the quick connector (32), and the outlet end pipeline (31) of the oxygenator (2) is connected to the pre-filling component (4) through the quick connector (32); Starting the pre-filling component (4) to perform pre-filling until the pipeline (31) is filled with liquid; Disconnecting the inlet end pipeline (31) of the pump head (1) from the pre-filling component (4) through the quick connector (32), and disconnecting the outlet end pipeline (31) of the oxygenator (2) from the pre-filling component (4) through the quick connector (32); The pipes at both ends of the pump head (1) are connected to the pipes at both ends of the oxygenator (2) respectively, so that the pump head (1) and the oxygenator (2) form a circulation path, and the pump head (1) is driven to circulate the liquid between the pump head (1) and the oxygenator (2); When the patient preparation is completed, the connection between the inlet end pipeline (31) of the pump head (1) and the outlet end pipeline (31) of the oxygenator (2) is disconnected through the quick connector (32), and the inlet of the pump head (1) is connected to the vascular cannula connected to the patient, and the outlet of the oxygenator (2) is connected to another vascular cannula connected to the patient.

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