Blood cell smear auxiliary device

By designing a blood cell smear auxiliary device, using blood filling tanks and adjustment components to accurately control blood dosage, and smear operation is achieved through the movement of the slides, the problems of low efficiency of blood cell smear preparation, unstable quality and high safety risks in the prior art are solved, and diagnostic accuracy and laboratory detection efficiency are significantly improved.

CN119880564APending Publication Date: 2025-04-25SHENZHEN SECOND PEOPLES HOSPITAL (SHENZHEN INST OF TRANSLATIONAL MEDICINE)
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Patent Information

Application Number
CN202510325089.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-19
Publication Date
2025-04-25

AI Technical Summary

Technical Problem

The existing hemocell smear technology has problems such as inconsistent operation, inefficiency, high safety risks, unstable smear quality and difficult standardization, resulting in insecure diagnostic accuracy and laboratory testing efficiency.

Method used

A blood cell smear auxiliary device is designed, including a blood filling pool and adjustment components. By adjusting the volume of the container, the blood usage is accurately controlled, the stability of the smear quality is improved, and the smear operation is realized through the movement of the slide, simplifying the operation process.

Benefits of technology

It significantly improves the preparation efficiency and quality of blood smears, reduces dependence on the operator's personal skills, improves the consistency and repeatability of smear results, reduces biosafety risks, and is suitable for widespread application in medical institutions at all levels.

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Abstract

The invention discloses a blood cell smear auxiliary device. The blood cell smear auxiliary device comprises a blood filling pool and an adjusting part, the blood filling pool is provided with a containing groove used for containing blood, the groove bottom face of the containing groove is opened to be used for being matched with a glass slide, and the adjusting part comprises a first adjusting piece and a second adjusting piece. The first adjusting piece and the second adjusting piece are oppositely arranged in the blood filling pool, and the first adjusting piece and the second adjusting piece can move so as to adjust the volume of the containing groove. According to the blood cell smear auxiliary device, the preparation efficiency and quality of the blood smear can be remarkably improved, and a more reliable sample is provided for hematological examination, so that the accuracy and efficiency of medical diagnosis are promoted.
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Description

Technical Field

[0001] The present application relates to the field of medical devices and biological detection technology, and in particular to a blood cell smear auxiliary device. Background Art

[0002] A blood smear (also called a blood smear or blood film) is a laboratory test method used to evaluate the morphology and quantity of various cells in the blood. This test is of great value for the preparation of blood smear samples, identification of cell morphology, and diagnosis of a variety of diseases. At present, the existing blood smear technology has the following shortcomings and disadvantages: (1) Operation consistency issues: Manual operation is heavily dependent on the skills and experience of the operator, resulting in possible differences in smears prepared by the same operator at different times; the quality differences between different operators are even more significant, and it is difficult to ensure stable smear quality. (2) Preparation efficiency and automation adaptation issues: The traditional manual smear method is time-consuming and inefficient when faced with a large number of samples; in addition, manual smear technology is often difficult to seamlessly adapt to existing automated blood cell analyzers, and additional standardization steps may be required to ensure compatibility between systems. (3) Operation safety issues: The complexity of manual operation leads to inevitable contact with blood during the process, increasing the risk of operators being infected with blood-borne pathogens. (4) Smear quality issues: Uneven cell distribution often occurs at the edge and tail of the smear, resulting in cells being too sparse or dense in some areas, thus affecting counting and subsequent analysis; in addition, the mechanical force applied during the preparation process may cause red blood cells to break or deform, affecting morphological judgment. (5) Drying, fixation and staining issues during sample processing: The empirical operation of manual smears in the past has resulted in uneven smears, different thicknesses and inconsistent blood volumes, which will affect the subsequent drying and fixation speeds, thereby changing cell morphology and affecting subsequent staining effects. (6) Sample standardization issues: Different laboratories have different smear preparation methods and lack unified quality control standards; at the same time, factors such as ambient temperature and humidity will also have a significant impact on smear quality. (7) Special cell loss issues: Since the proportion of rare or abnormal cells in the overall sample is relatively low, it may be difficult to retain these important information during the smear process, which will pose a challenge to the early diagnosis of diseases such as leukemia. (8) High blood sample volume requirements: Traditional smear technology usually requires a large amount of blood samples. For newborns or critically ill patients, it is often difficult to collect enough samples. In summary, the existing blood smear sample preparation technology has many shortcomings such as inconsistent operation, low efficiency, high safety risk, unstable smear quality and difficulty in standardization. The improvements made by this patent to these problems will help improve diagnostic accuracy and laboratory testing efficiency and promote the development of automation and standardization technology. Summary of the invention

[0003] Based on this, it is necessary to provide a blood cell smear auxiliary device. The blood cell smear auxiliary device of the present invention can solve at least one or more technical problems in the background technology. The blood cell smear auxiliary device of the present invention can significantly improve the preparation efficiency and quality of blood smears, provide more reliable samples for hematological examinations, and thus promote the accuracy and efficiency of medical diagnosis.

[0004] An embodiment of the present application provides a blood cell smear auxiliary device.

[0005] A blood cell smear auxiliary device includes a blood filling pool and an adjusting component, wherein the blood filling pool has a receiving groove for receiving blood, the bottom surface of the receiving groove is open for matching with a slide, and the adjusting component includes a first adjusting piece and a second adjusting piece, the first adjusting piece and the second adjusting piece are relatively arranged in the blood filling pool, and the first adjusting piece and the second adjusting piece can be moved to adjust the volume of the receiving groove.

[0006] In some embodiments, the accommodating groove is an elongated groove, and the groove width of the accommodating groove is greater than the groove bottom width of the accommodating groove, so that the accommodating groove is an inverted trapezoidal groove as a whole.

[0007] In some embodiments, the blood pool includes a first fixing plate, a second fixing plate and a side plate, the first fixing plate and the second fixing plate are arranged relatively spaced apart, a plurality of side plates are connected between the first fixing plate and the second fixing plate, the first fixing plate, the second fixing plate and the side plates constitute the blood pool, and the space enclosed by the first fixing plate, the second fixing plate and the side plates forms the accommodating groove.

[0008] In some embodiments, the distance between the first fixing plate and the second fixing plate gradually increases from a side matched with the glass slide to a side away from the glass slide.

[0009] In some embodiments, the first adjusting sheet is disposed close to the first fixing plate, the first adjusting sheet is parallel to the first fixing plate, and the first adjusting sheet can move away from or close to the first fixing plate.

[0010] In some embodiments, the second adjusting piece is disposed close to the second fixing plate, the second adjusting piece is parallel to the second fixing plate, and the second adjusting piece can move away from or close to the second fixing plate.

[0011] In some embodiments, the blood pool is made of a material having biocompatibility. Preferably, the blood pool is made of a material having medical grade polypropylene plastic or polystyrene plastic.

[0012] In some embodiments, the first adjusting sheet and / or the second adjusting sheet are made of a material having biocompatibility. Preferably, the first adjusting sheet and / or the second adjusting sheet are made of a material having medical grade polypropylene plastic or polystyrene plastic.

[0013] In some embodiments, the blood cell smear auxiliary device also includes a rotating component, which is installed on the blood filling pool. The rotating component is also connected to the first adjusting plate and / or the second adjusting plate, and the rotating component can adjust the distance between the first adjusting plate and the second adjusting plate.

[0014] In some embodiments, the rotating component includes a rotating knob and a transmission structure. The rotating knob can be rotatably connected to the blood filling pool. The rotating knob is connected to the transmission structure and can drive the transmission structure to move through the rotation of the rotation. The transmission structure is connected to the first adjusting plate and / or the second adjusting plate.

[0015] In some embodiments, a plurality of scale lines are provided on the rotating knob, and an indicator line is provided on the outer wall of the blood pool. When the rotating knob is rotated to different scale lines, the first adjusting plate and / or the second adjusting plate can adjust the containing groove to a predetermined volume.

[0016] In some embodiments, the blood cell smear auxiliary device also includes a glass slide, which cooperates with the blood filling pool, and the blood filling pool is movably connected to the glass slide, and the blood filling pool can move along the glass slide to achieve smear.

[0017] The above-mentioned blood cell smear auxiliary device can adjust the volume of the receiving tank as needed, can accurately control the amount of blood used, and improve the stability of the smear quality. When smearing, after adding blood to the receiving tank, the blood filling pool is moved along the glass slide to achieve smearing. The operation is simple, reducing the dependence on the operator's personal skills, and can improve the consistency and repeatability of the smear results. The present application contains a blood filling pool and an adjustment component, which is used in conjunction with a glass slide. It has a simple structure and low cost, so that it can be widely used in medical institutions at all levels. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present application, and those skilled in the art can obtain other drawings based on these drawings without creative work.

[0019] In order to more completely understand the present application and its beneficial effects, the following description will be given in conjunction with the accompanying drawings. In the following description, the same reference numerals represent the same parts.

[0020] Figure 1 It is a side view of a blood cell smear auxiliary device according to an embodiment of the present invention;

[0021] Figure 2 The figure is a top view of a blood cell smear auxiliary device according to an embodiment of the present invention.

[0022] Description of Reference Numerals

[0023] 10. Blood cell smear auxiliary device; 100. Blood filling pool; 101. Receiving groove; 102. First fixing plate; 103. Second fixing plate; 104. Side plate; 200. Adjusting component; 201. First adjusting plate; 202. Second adjusting plate; 300. Rotating knob; 400. Glass slide. DETAILED DESCRIPTION

[0024] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0025] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0026] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0027] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0028] In the description of the present invention, "several" means more than one, "many" means more than two, "greater than", "less than", "exceed" etc. are understood to exclude the number itself, and "above", "below", "within" etc. are understood to include the number itself. If there is a description of "first" or "second", it is only used for the purpose of distinguishing the technical features, and cannot be understood as indicating or implying the relative importance or implicitly indicating the number of the indicated technical features or implicitly indicating the order of the indicated technical features.

[0029] In this article, "optionally", "optional", "optional" means optional, that is, it means to be selected from any of the two parallel solutions of "yes" or "no". If there are multiple "optional" in a technical solution, unless otherwise specified and there is no contradiction or mutual restriction, each "optional" is independent. In this application, the descriptions such as "optionally contain" and "optionally include" mean "contain or not contain".

[0030] In the present application, when it comes to a numerical interval (i.e., a numerical range), unless otherwise specified, the distribution of the optional numerical values ​​in the numerical interval is considered to be continuous, and includes the two numerical endpoints (i.e., the minimum and maximum values) of the numerical interval, and each numerical value between the two numerical endpoints. Unless otherwise specified, when the numerical interval only refers to an integer in the numerical interval, it includes the two endpoint integers of the numerical range, and each integer between the two endpoints, which is equivalent to directly listing each integer. When multiple numerical ranges are provided to describe features or characteristics, these numerical ranges can be combined. In other words, unless otherwise specified, the numerical range disclosed in the present application should be understood to include any and all sub-ranges included therein. The "numerical value" in the numerical interval can be any quantitative value, such as a number, a percentage, a ratio, etc. "Numerical interval" allows for a broad range of quantitative intervals such as percentage intervals, ratio intervals, and ratio intervals.

[0031] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which the present invention belongs. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more of the related listed items.

[0032] The embodiment of the present application provides a blood cell smear auxiliary device to solve at least one of the following problems existing in the existing blood smear preparation technology: (1) When manually preparing a blood smear, it is difficult for the operator to accurately control the amount of blood, resulting in unstable smear quality; (2) The traditional method relies on the operator's experience and skills, resulting in poor consistency and repeatability of the smear results; (3) The existing automated equipment is large in size and high in cost, and is not suitable for widespread use in primary medical institutions; (4) The amount of blood sample used is large, which may cause unnecessary waste in some cases. The blood cell smear auxiliary device will be described below in conjunction with the accompanying drawings.

[0033] The blood cell smear auxiliary device 10 provided in the embodiment of the present application is exemplary, see Figure 1 As shown, Figure 1 The side structure diagram of the blood cell smear auxiliary device 10 provided in the embodiment of the present application. The blood cell smear auxiliary device 10 of the present application can be used for the preparation of blood cell smears.

[0034] In order to more clearly illustrate the structure of the blood cell smear auxiliary device 10 , the blood cell smear auxiliary device 10 will be introduced below with reference to the accompanying drawings.

[0035] For example, see Figure 1As shown, a blood cell smear auxiliary device 10 includes a blood pool 100 and an adjusting component 200. The blood pool 100 has a receiving groove 101 for receiving blood. The bottom surface of the receiving groove 101 is open to match the slide 400. The adjusting component 200 includes a first adjusting piece 201 and a second adjusting piece 202. The first adjusting piece 201 and the second adjusting piece 202 are relatively arranged on the blood pool 100. The first adjusting piece 201 and the second adjusting piece 202 can be moved to adjust the volume of the receiving groove 101.

[0036] The blood cell smear auxiliary device 10 can adjust the volume of the receiving tank 101 as needed, can accurately control the amount of blood used, and improve the stability of the smear quality. When smearing, after adding blood to the receiving tank 101, the blood filling pool 100 is moved along the slide 400 to achieve smearing. The operation is simple, reducing the dependence on the operator's personal skills, and can improve the consistency and repeatability of the smear results. The present application contains a blood filling pool 100 and an adjustment component 200, which are used in conjunction with a slide 400. It has a simple structure and low cost, so that it can be widely used in medical institutions at all levels and is suitable for large-scale production.

[0037] It should be noted that see Figure 2 As shown, Figure 2 This is a top view schematic diagram of a blood cell smear auxiliary device according to an embodiment of the present invention. The shape and size of the first adjusting piece 201 and the shape and size of the second adjusting piece 202 are both adapted to the shape and size of the side of the blood-filled pool 100. The side edges of the first adjusting piece 201 and the side edges of the second adjusting piece 202 are both in contact with and fitted to the inner wall of the blood-filled pool 100, and can slide and dynamically seal with the inner wall of the blood-filled pool 100 to achieve the movement of the first adjusting piece 201 and the second adjusting piece 202 along the inner wall of the blood-filled pool 100. In this way, the first adjusting piece 201 and the second adjusting piece 202 can adjust the size of the space between the first adjusting piece 201 and the second adjusting piece 202 by moving closer to or away from each other, thereby achieving the purpose of adjusting the volume of the accommodating groove 101.

[0038] In some embodiments, the receiving groove 101 is a long strip groove. The width of the notch of the receiving groove 101 is greater than the width of the bottom of the receiving groove 101, so that the receiving groove 101 is an inverted trapezoidal groove as a whole. The inverted trapezoidal groove design of the present application facilitates blood dripping and bubble removal.

[0039] In some embodiments, the blood pool 100 includes a first fixing plate 102, a second fixing plate 103, and a side plate 104. The first fixing plate 102 and the second fixing plate 103 are arranged relatively spaced apart. A plurality of side plates 104 are connected between the first fixing plate 102 and the second fixing plate 103. The first fixing plate 102, the second fixing plate 103, and the side plates 104 constitute the blood pool 100. The space enclosed by the first fixing plate 102, the second fixing plate 103, and the side plates 104 forms the receiving groove 101.

[0040] In some embodiments, the distance between the first fixing plate 102 and the second fixing plate 103 gradually increases from a side matched with the glass slide 400 to a side away from the glass slide 400 .

[0041] In some embodiments, the first adjusting piece 201 is disposed close to the first fixing plate 102. The first adjusting piece 201 is parallel to the first fixing plate 102. The first adjusting piece can move away from or close to the first fixing plate 102. At this time, the shape and size of the first adjusting piece 201 are adapted to the shape and size of the first fixing plate 102.

[0042] In some embodiments, the second adjusting piece 202 is disposed close to the second fixing plate 103. The second adjusting piece 202 is parallel to the second fixing plate 103, and the second adjusting piece can move away from or close to the second fixing plate 103. The present application uses the adjustable first adjusting piece 201 and the second adjusting piece 202 to accurately control the amount of blood sample to meet different smear requirements. At this time, the shape and size of the second adjusting piece 202 are adapted to the shape and size of the second fixing plate 103.

[0043] In some embodiments, the first adjustment sheet 201 and the second adjustment sheet 202 may also be parallel to the side panel 104. Correspondingly, at this time, the shape and size of the first adjustment sheet 201 are adapted to the shape and size of one of the side panels 104, and the shape and size of the second adjustment sheet 202 are adapted to the shape and size of the other side panel 1043.

[0044] In some embodiments, the blood pool 100 is made of a biocompatible material.

[0045] Preferably, the blood pool 100 is made of medical grade polypropylene plastic or polystyrene plastic. Medical grade polypropylene plastic or polystyrene plastic can reduce manufacturing costs.

[0046] In some embodiments, the first adjustment sheet 201 is made of a biocompatible material.

[0047] In some embodiments, the second adjustment sheet 202 is made of a biocompatible material.

[0048] Preferably, the first adjustment sheet 201 is made of medical grade polypropylene plastic or polystyrene plastic. The second adjustment sheet 202 is made of medical grade polypropylene plastic or polystyrene plastic.

[0049] In some embodiments, the blood cell smear auxiliary device 10 also includes a rotating component. The rotating component is installed in the blood filling pool 100. The rotating component is also connected to the first adjusting piece 201 and / or the second adjusting piece 202. The rotating component can adjust the distance between the first adjusting piece 201 and the second adjusting piece 202. For example, the rotating component is connected to the first adjusting piece 201 and the second adjusting piece 202 at the same time, and when the rotating component is in motion, it can drive the first adjusting piece 201 and the second adjusting piece 202 to move, and the above-mentioned movement can be synchronous movement or asynchronous movement, wherein synchronous movement refers to the first adjusting piece 201 and the second adjusting piece 202 moving towards each other or moving away from each other at the same time. Asynchronous movement refers to the movement of one of the first adjusting piece 201 and the second adjusting piece 202.

[0050] In some embodiments, the rotating component includes a rotating knob 300 and a transmission structure. The rotating knob 300 is rotatably connected to the blood filling pool 100. The rotating knob 300 is connected to the transmission structure and can drive the transmission structure to move through the rotation of the rotation. The transmission structure is connected to the first adjustment piece 201 and / or the second adjustment piece 202. The transmission structure is not shown in the drawings.

[0051] In some of the embodiments, the transmission structure may be a transmission form such as meshing transmission, hinge transmission, and screw transmission.

[0052] For example, in some embodiments, the transmission structure is in the following form: a gear is provided on the shaft of the rotating knob 300, and a chain is rotatably connected to the first fixed plate 102 and the second fixed plate 103, and the chain extends from the first fixed plate 102 to the second fixed plate 103, and the chain is meshed with the gear. The first adjusting piece 201 or the second adjusting piece 202 is connected to the chain through a connecting block. When the gear rotates, the chain is driven to rotate, and the rotation of the chain drives the position of the first adjusting piece 201 or the second adjusting piece 202 to change, thereby adjusting the distance between the first adjusting piece 201 and the second adjusting piece 202 and changing the effective volume of the 100 blood filling pool.

[0053] For another example, in some embodiments, the transmission structure is in the following form: the first adjustment piece 201 and the second adjustment piece 202 are respectively arranged parallel to the two side plates 104, the shaft of the rotating knob 300 is provided with an external thread, a guide rod is provided between the two side plates 104, and the first adjustment piece 201 or the second adjustment piece 202 is slidably connected to the guide rod. The first adjustment piece 201 or the second adjustment piece 202 is provided with an internal thread hole. The shaft of the rotating knob 300 is threadedly matched with the internal thread hole of the first adjustment piece 201 or the second adjustment piece 202. When the rotating knob 300 is rotated, the first adjustment piece 201 or the second adjustment piece 202 is driven by the thread to move linearly along the axis direction of the rotating knob 300, thereby adjusting the distance between the first adjustment piece 201 and the second adjustment piece 202, and changing the effective volume of the 100 blood filling pool. The thread transmission has a self-locking function, which can accurately control the position of the first adjustment piece 201 and the second adjustment piece 202 to prevent position displacement caused by vibration.

[0054] The following settings can be made on the rotation distance of the rotating knob 300. The distance that the first adjusting piece 201 or the second adjusting piece 202 moves along the axial direction of the rotating knob 300 is determined by the pitch. For example, when the pitch is 0.8 mm, the rotating knob 300 is turned. When the rotating knob 300 is rotated by a certain angle, such as 15° (the angle of rotation along the circumference in the counterclockwise or clockwise direction), the first adjusting piece 201 or the second adjusting piece 202 moves 0.8 mm. By using the scale marks on the rotating knob 300, the operator can intuitively adjust the rotating knob 300 to the desired position, thereby accurately controlling the amount of blood. The scales on the rotating knob 300 are distributed along the circumferential direction, corresponding one-to-one to the moving distance of the first adjusting piece 201 or the second adjusting piece 202, to ensure accurate control of the amount of blood. It should be noted that the attached Figure 1 The scale marks on the middle rotating knob 300 are only examples, and the specific scale distribution can be set according to the rotation angle and pitch.

[0055] In some embodiments, a plurality of scale lines are provided on the rotating knob 300. An indicator line is provided on the outer wall of the blood filling pool 100. When the rotating knob 300 is rotated to different scale lines, the first adjustment piece 201 and / or the second adjustment piece 202 can adjust the volume of the containing tank 101 to a predetermined volume. The present application adopts a knob scale design to achieve quantitative control of the blood volume and improve the consistency of the smear.

[0056] The scale lines correspond to corresponding scale values. The scale range can be set according to actual needs, such as 1 μL~20 μL, to meet the needs of different types of blood cell smear preparation. The minimum scale can be set to 1 μL, and the maximum scale can be determined according to the maximum capacity of the blood pool 100, such as 20 μL. The scale lines are experimentally verified and calibrated to ensure their accuracy and reliability.

[0057] In some embodiments, the blood cell smear auxiliary device 10 further includes a glass slide 400. The glass slide 400 cooperates with the blood filling pool 100. The blood filling pool 100 is movably connected to the glass slide 400, and the blood filling pool 100 can move along the glass slide 400 to achieve smear. The bottom of the blood filling pool 100 is designed with a card slot or other fixing structure, which can fix the standard size glass slide 400 in a suitable position of the blood filling pool 100 to ensure the stability and consistency of the smear process. For non-standard size glass slides 400, adapters or other adjustment mechanisms can be provided to ensure the versatility of the device.

[0058] The smear operation process of the blood smear preparation device of the present invention comprises the following steps:

[0059] (1) Insert a standard-sized slide glass 400 into the bottom of the blood-filled pool 100.

[0060] (2) Add the blood sample dropwise into the receiving tank 101 of the blood pool 100 .

[0061] (3) According to the required blood volume, rotate the knob 300 to the corresponding scale line.

[0062] (4) Push the blood pool 100 steadily onto the glass slide 400 so that the blood forms a uniform thin layer on the glass slide 400.

[0063] (5) Based on the results of the first smear, fine-tune the knob by 300 to obtain the optimal smear thickness and cell density.

[0064] Compared with the prior art, the blood smear preparation device of the present invention has the following advantages and positive effects:

[0065] (1) Precise control of blood volume: The innovative design of the adjustment knob 300 and its scale lines enables the operator to precisely control the required blood volume, thereby significantly improving the consistency and repeatability of smear quality and completely solving the problem of difficulty in controlling blood volume in traditional manual preparation.

[0066] (2) Easy operation and lower technical threshold: The device greatly simplifies the smear preparation process. The operator only needs to turn the knob 300 to the preset scale to complete the blood volume adjustment. In this way, even people who lack rich experience can easily prepare high-quality blood smears, thereby reducing the dependence on professional skills.

[0067] (3) Improve efficiency and save time: Compared with traditional methods, this device can quickly complete smear preparation, significantly improve work efficiency, and effectively reduce the need to repeat smear preparation due to unqualified smears, thereby saving valuable laboratory time and resources.

[0068] (4) Save blood samples: The combination of the blood pool 100 and the precise adjustment mechanism allows each smear to use only the minimum amount of blood necessary. This feature is particularly important when dealing with precious or difficult-to-collect blood samples, helping to maximize sample utilization.

[0069] (5) Strong adaptability and compatibility: By adjusting the knob 300 to different scale lines, the device can flexibly adapt to various blood test needs such as thick smears or thin smears. At the same time, its good compatibility with standard slides 400 enhances its wide application in various laboratory environments.

[0070] (6) Good cost-effectiveness: Compared with expensive automated equipment, this device has a simple structure, low manufacturing cost, and is easy to maintain and clean. In long-term use, its significant cost-effectiveness makes it an ideal choice for medical institutions and laboratories at all levels.

[0071] (7) Improved diagnostic accuracy: Due to the significant improvement in smear quality and consistency, the blood smears prepared by this device provide more reliable samples for subsequent microscopic examination and pathological analysis, indirectly improving the diagnostic accuracy of hematological testing and facilitating early detection and accurate diagnosis of diseases.

[0072] (8) Reduced biosafety risks: The design of the device effectively reduces the operator’s chance of direct contact with blood during the preparation process, thereby reducing the risk of blood-borne pathogen infection and providing a safer working environment for medical staff and laboratory workers.

[0073] In summary, the blood smear preparation device of the present invention, with its innovative design, not only solves the shortcomings of traditional methods in terms of blood volume control, operational convenience, efficiency and safety, but also significantly improves the overall performance and diagnostic accuracy of the product, showing broad clinical application prospects.

[0074] In the above embodiments, the description of each embodiment has its own emphasis. For parts that are not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0075] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0076] The above-mentioned embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the patent of the present invention. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A blood cell smear auxiliary device, characterized in that: It includes a blood filling pool and an adjusting component, the blood filling pool has a receiving groove for receiving blood, the bottom surface of the receiving groove is open for matching with a slide, the adjusting component includes a first adjusting piece and a second adjusting piece, the first adjusting piece and the second adjusting piece are relatively arranged in the blood filling pool, and the first adjusting piece and the second adjusting piece can be moved to adjust the volume of the receiving groove.

2. The blood cell smear auxiliary device according to claim 1, characterized in that: The receiving groove is in the form of an elongated groove, and the width of the groove opening of the receiving groove is greater than the width of the groove bottom of the receiving groove, so that the receiving groove is in the form of an inverted trapezoidal groove as a whole.

3. The blood cell smear auxiliary device according to claim 1, characterized in that: The blood-filled pool includes a first fixing plate, a second fixing plate and a side plate. The first fixing plate and the second fixing plate are arranged relatively spaced apart. A plurality of side plates are connected between the first fixing plate and the second fixing plate. The first fixing plate, the second fixing plate and the side plates constitute the blood-filled pool. The space enclosed by the first fixing plate, the second fixing plate and the side plates forms the accommodating groove.

4. The blood cell smear auxiliary device according to claim 3, characterized in that: The distance between the first fixing plate and the second fixing plate gradually increases from the side matched with the glass slide to the side away from the glass slide.

5. The blood cell smear auxiliary device according to claim 3, characterized in that: The first adjusting piece is arranged close to the first fixing plate, the first adjusting piece is parallel to the first fixing plate, and the first adjusting piece can move away from or close to the first fixing plate; And / or, the second adjusting piece is arranged close to the second fixing plate, the second adjusting piece is parallel to the second fixing plate, and the second adjusting piece can move away from or close to the second fixing plate.

6. The blood cell smear auxiliary device according to claim 1, characterized in that: The preparation material of the blood-filled pool includes a biocompatible material. Preferably, the preparation material of the blood-filled pool includes medical-grade polypropylene plastic or polystyrene plastic; And / or, the first adjusting sheet and / or the second adjusting sheet are made of a material having biocompatibility. Preferably, the first adjusting sheet and / or the second adjusting sheet are made of a material having medical grade polypropylene plastic or polystyrene plastic.

7. The blood cell smear auxiliary device according to any one of claims 1 to 6, characterized in that: The blood cell smear auxiliary device also includes a rotating component, which is installed on the blood filling pool. The rotating component is also connected to the first adjusting piece and / or the second adjusting piece, and the rotating component can adjust the distance between the first adjusting piece and the second adjusting piece.

8. The blood cell smear auxiliary device according to claim 7, characterized in that: The rotating component includes a rotating knob and a transmission structure. The rotating knob can be rotatably connected to the blood filling pool. The rotating knob is connected to the transmission structure and can drive the transmission structure to move through the rotation of the rotation. The transmission structure is connected to the first adjusting plate and / or the second adjusting plate.

9. The blood cell smear auxiliary device according to claim 8, characterized in that: The rotating knob is provided with a plurality of scale lines, and the outer wall of the blood pool is provided with an indicator line. When the rotating knob is rotated to different scale lines, the first adjusting piece and / or the second adjusting piece can adjust the containing groove to a predetermined volume.

10. The blood cell smear auxiliary device according to any one of claims 1 to 6, 8 to 9, characterized in that: The blood cell smear auxiliary device also includes a glass slide, which cooperates with the blood filling pool. The blood filling pool is movably connected to the glass slide, and the blood filling pool can move along the glass slide to achieve smear.