Dyeing analysis device for pathological diagnosis

Abstract

The invention discloses a staining analysis device for pathological diagnosis, and particularly relates to the field of pathological diagnosis section staining, the staining analysis device comprises a casing and a staining bracket, a plurality of groups of staining pools are arranged in the casing, each staining pool comprises a staining liquid box and a flushing box, a plurality of glass slides are vertically placed on the staining bracket, sections are fixed on the surfaces of the plurality of glass slides, and the staining pools are arranged on the staining bracket. A bracket driving mechanism is further arranged in the machine shell, and the bracket driving mechanism is used for placing the dyeing bracket in the dyeing pool. According to the invention, by arranging the unfoldable dyeing bracket, the dyeing bracket with the section is unfolded when being put into the washing box, and the swinging angle of the section is in an inclined state, so that the effect of conveniently observing the water flow direction and the washing degree in the washing process can be achieved, and the dyeing effect in the washing process can be conveniently controlled; and meanwhile, water flow can slide down along the inclined surface of the slice, so that over-strong scouring to a certain local part of the surface of the slice is reduced, and excessive loss of dye in the local part is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of pathological diagnosis section staining, and more specifically, to a staining analysis device for pathological diagnosis. Background Art

[0002] Pathological diagnostic staining is an important step in histological and pathological analysis. Staining can enhance the contrast of tissue sections, thereby helping pathologists observe and judge diseases. HE staining (hematoxylin-eosin staining) is a staining technique widely used in pathology and histology. It is used to observe the structure and cell morphology of tissue sections. It is one of the most commonly used staining methods and can clearly show the morphological characteristics of the cell nucleus and cytoplasm, as well as the basic structure and pathological changes of the tissue.

[0003] Currently, the staining steps for slices during pathological diagnosis include placing the slices in hematoxylin and eosin staining solutions for staining. In the hematoxylin staining, after the hematoxylin staining, the slices need to be rinsed with distilled water to remove the hematoxylin residues, and then placed in a hydrochloric acid alcohol solution for differentiation. After differentiation, they are rinsed with distilled water to remove the hydrochloric acid alcohol residues, and then placed in ammonia water for anti-blueing. After anti-blueing, they are rinsed with distilled water, and then placed in an alkaline fuchsin solution for re-staining. After re-staining, they are rinsed with distilled water to remove the alkaline fuchsin residues, and then eosin staining is finally performed. After the staining is completed, they are rinsed with distilled water to remove the eosin residues, which includes multiple rinses of the slices.

[0004] At present, in the actual use of pathological diagnosis, in order to efficiently stain multiple slices, a professionally designed slice staining rack (also called a staining tray or a staining basket) is usually used to neatly insert multiple slides into the staining tray, and a certain distance is maintained between each slide so that the staining solution can fully contact the slice surface without adhesion or affecting the uniformity of staining. The distance also needs to be set smaller to facilitate staining of multiple slices at the same time to improve the staining efficiency. Since the distance between multiple slices is relatively close, it is necessary to take out the slices several times during rinsing to observe the staining effect of the slices to avoid excessive rinsing, resulting in excessive or insufficient rinsing of the cell nucleus and cytoplasm, and ultimately resulting in a weakened overall staining effect of the slice, a reduced contrast between the cell nucleus and the cytoplasm, and a problem that is not conducive to observation under a microscope. However, multiple rinsing is usually required during the staining process. During multiple rinsing and multiple rinsing processes, the slices need to be taken out several times to observe the staining condition, which will affect the staining efficiency. Summary of the invention

[0005] The present invention provides a staining and analysis device for pathological diagnosis, and aims to solve the following problem: in order to ensure the staining efficiency, the existing staining tray places multiple slices on the staining tray for simultaneous staining, but the interval between two adjacent slices is small, resulting in the need to take out the slices multiple times to observe the staining effect of the slices during washing to avoid excessive washing, which in turn affects the staining efficiency due to the multiple removal of slices to observe the staining effect.

[0006] To achieve the above object, the present invention provides the following technical solution: A staining analysis device for pathological diagnosis, characterized in that it comprises: a housing, a staining bracket, a sliding drive mechanism and a flushing component, wherein a plurality of staining pools are arranged in the housing, the staining pools include a dye box and a flushing box, and a bracket drive mechanism for driving the staining bracket to move is also arranged in the housing; The staining bracket is provided with multiple groups of supporting components, and the supporting components include a fixed frame and two sliding frames, the fixed frame is fixedly arranged on the staining bracket, the sliding frame is slidably arranged on the staining bracket, and the fixed frame and the sliding frame are both hingedly provided with a placement frame for placing a slide glass; A plurality of pushers and toggle members are slidably arranged in the dyeing bracket, and the sliding drive mechanism is used to drive the pushers and toggle members to slide, so that the plurality of pushers push two adjacent sliding racks to slide out of the dyeing bracket in opposite directions, and the plurality of toggle members toggle the plurality of placement racks to swing angles.

[0007] In a preferred embodiment, a slide is slidably arranged in the dyeing tray, a plurality of pushers and toggle members are fixedly arranged on the slide, a plurality of sliding frames are provided with guide openings at the bottom, the guide openings are inclined, the pushers are movably connected in the guide openings, and the inclination directions of the guide openings at the bottoms of two adjacent sliding frames are opposite.

[0008] In a preferred embodiment, a rubber pad is fixedly provided on the placement rack, and the rubber pad is used to fix the glass slide on the placement rack. Side holes are opened on the sides of the plurality of placement racks, and the toggle members are movably arranged in the side holes.

[0009] In a preferred embodiment, the sliding drive mechanism is a sliding drive component 1, which includes a stop block, which is fixedly arranged on the bottom inner wall of the washing box, and the top of the stop block is inclined. An opening is provided at the bottom of the dyeing bracket, and an abutment groove is provided at the bottom of the slide. The top inner wall of the abutment groove is inclined, and the top of the stop block and the top inner wall of the abutment groove have the same inclination angle. An elastic member 1 is fixedly arranged on one side of the slide, and the end of the elastic member 1 away from the slide is fixedly arranged on the dyeing bracket.

[0010] In a preferred embodiment, a slide rod 1 is fixedly provided on the other side of the slide seat, the slide rod 1 is slidably provided in the dyeing bracket, and a limit block 1 is fixedly provided on the slide rod 1, and the limit block 1 is movably abutted against the dyeing bracket.

[0011] In a preferred embodiment, the sliding drive mechanism is a sliding drive component 2, which includes a driving member fixedly mounted on the dye box, an output end of the driving member extending into the dye box, and a push rod fixedly arranged thereon, two elastic members and two slide rods fixedly arranged on both sides of the slide seat, respectively, the slide rod 2 is slidably arranged in the dyeing bracket, a limit block 2 is fixedly arranged on the slide rod 2, the limit block 2 is movably abutted against the dyeing bracket, and a bottom groove is provided at the bottom of the slide rod 2, the push rod is located in the bottom groove, and the push rod is movably abutted against the inner wall of the bottom groove.

[0012] In a preferred embodiment, the bracket driving mechanism includes a linear drive component 1, a linear drive component 2 and a clamping component, the clamping component is used to clamp the dyeing bracket, the linear drive component 2 is installed at the output end of the linear drive component 1, the clamping component is installed at the output end of the linear drive component 2, the linear drive component 2 is used to drive the dyeing bracket to move vertically linearly, and the linear drive component 1 is used to drive the dyeing bracket to move horizontally linearly.

[0013] In a preferred embodiment, the clamping assembly includes a shell, which is fixedly mounted on the output end of the linear drive assembly 2, a power component is mounted in the shell, a gear is mounted on the output end of the power component, two racks are slidably arranged in the shell, the sides of the two racks close to each other are meshed with the gears, and clamping seats are fixedly mounted on the two racks, and positioning shafts are mounted on the two clamping seats, a top frame is mounted on the dyeing bracket, a positioning hole is opened on the top frame, and the positioning shaft is adapted to the positioning hole.

[0014] In a preferred embodiment, a mobile flushing mechanism is also provided in the casing, and the mobile flushing mechanism includes a linear drive component three and a linear drive component four. The linear drive component four is installed at the output end of the linear drive component three, and the flushing component is installed at the output end of the linear drive component four. The linear drive component three is used to drive the flushing component to move horizontally and linearly left and right, and the linear drive component four is used to drive the flushing component to move horizontally and linearly forward and backward.

[0015] In a preferred embodiment, the flushing component includes a water pump, which is installed at the output end of the linear drive component 4. A flushing pipe is installed at the water outlet end of the water pump, and the output end of the flushing pipe points to the slice.

[0016] The beneficial effects of the present invention are: The present invention provides an expandable dyeing bracket so that the dyeing bracket with slices can be expanded when placed in a flushing box, and the swing angle of the slices can be in an inclined state. During the flushing process, it is convenient to observe the direction of water flow and the flushing degree, and it is convenient to control the dyeing effect during the water washing process. At the same time, the water flow can slide along the inclined surface of the slice, reducing excessive flushing of a certain part of the slice surface and avoiding excessive loss of dye in the local area. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention.

[0018] Figure 2 It is a schematic diagram of the three-dimensional structure of the bracket driving mechanism and multiple groups of dyeing tanks of the present invention.

[0019] Figure 3 It is a three-dimensional structural schematic diagram of the dyeing bracket and the clamping assembly of the present invention.

[0020] Figure 4 It is a schematic diagram of the three-dimensional structure of the dyeing bracket of the present invention.

[0021] Figure 5 It is a schematic diagram of the unfolded state of the dyeing bracket of the present invention.

[0022] Figure 6 It is a partial three-dimensional structural schematic diagram of the dyeing bracket of the present invention.

[0023] Figure 7 It is a three-dimensional schematic diagram of the slide seat of the present invention.

[0024] Figure 8 Schematic diagrams of the sliding frame of the present invention at different angles.

[0025] Fig. 9 It is a schematic diagram of the state of the sliding frame of the present invention after the dyeing bracket is unfolded.

[0026] Fig.10 It is a schematic diagram of the unfolding process of the sliding frame of the present invention.

[0027] Fig.11 It is a schematic diagram of the swinging state of the placement rack of the present invention.

[0028] Fig.12 The cross-sectional structure diagram of the sliding drive assembly of the present invention is shown in FIG. Figure 1 .

[0029] Fig.13 The cross-sectional structure diagram of the sliding drive assembly of the present invention is shown in FIG. Figure 2 .

[0030] Fig.14 It is a schematic cross-sectional view of the sliding drive assembly 2 of the present invention.

[0031] Fig.15 Exploded view of the clamping assembly of the present invention.

[0032] Fig.16 It is a schematic diagram of the three-dimensional structure of the mobile flushing mechanism of the present invention.

[0033] Fig.17 for Fig.12 Enlarged view of part A.

[0034] Fig.18 for Fig.14 Enlarged view of part B.

[0035] The accompanying drawings are marked as follows: 1, housing; 11, dyeing tank; 111, dye box; 112, washing box; 2, dyeing bracket; 21, top frame; 211, positioning hole; 22, supporting assembly; 221, fixed frame; 222, sliding frame; 2221, guide opening; 23, placement frame; 231, rubber pad; 232, side hole; 24, sliding seat; 241, pushing member; 242, toggle member; 25, sliding drive assembly 1; 251, abutment block; 252, opening; 253, abutment groove; 254, elastic member 1; 255, sliding rod 1; 256, limit block 1; 3, slide glass; 31. Slicing; 4. Bracket driving mechanism; 41. Linear driving component one; 42. Linear driving component two; 43. Clamping component; 431. Shell; 432. Power component; 433. Gear; 434. Rack; 435. Clamping seat; 436. Positioning shaft; 5. Mobile flushing mechanism; 51. Linear driving component three; 52. Linear driving component four; 53. Flushing component; 531. Water pump; 532. Flushing pipe; 6. Sliding driving component two; 61. Driving member; 62. Push rod; 63. Elastic member two; 64. Sliding rod two; 641. Bottom groove; 65. Limit block two. DETAILED DESCRIPTION

[0036] The present application is further described in detail below in conjunction with the accompanying drawings. It is necessary to point out here that the following specific implementation methods are only used to further illustrate the present application and cannot be understood as limiting the scope of protection of the present application. Technical personnel in this field can make some non-essential improvements and adjustments to the present application based on the above application content.

[0037] Refer to the instruction manual Figures 1 to 18A staining and analysis device for pathological diagnosis, comprising: a housing 1 and a staining bracket 2, wherein a plurality of staining pools 11 are arranged in the housing 1, and the plurality of staining pools 11 are evenly arranged in a linear array in the housing 1, the staining pools 11 include a dye box 111 and a flushing box 112, a plurality of slides 3 arranged in a linear array are evenly placed on the staining bracket 2, and sections 31 are fixed on the surfaces of the plurality of slides 3, and a bracket driving mechanism 4 is also arranged in the housing 1, and the bracket driving mechanism 4 is used to place the staining bracket 2 in the staining pool 11 to stain and flush the sections 31; The staining tray 2 is provided with a plurality of support components 22, and the plurality of support components 22 are evenly arranged in a linear array on the staining tray 2. The support components 22 include a fixed frame 221 and two sliding frames 222. The fixed frame 221 is fixedly provided on the staining tray 2, and the sliding frame 222 is slidably provided on the staining tray 2. A placement frame 23 is hingedly provided on the fixed frame 221 and the sliding frame 222, and the slide 3 is placed on the placement frame 23. A slide 24 is slidably arranged in the staining bracket 2, and a plurality of pushers 241 and toggles 242 are fixedly arranged on the slide 24. The plurality of pushers 241 are movably arranged in the corresponding sliding racks 222, and the plurality of toggles 242 are movably arranged in the corresponding placement racks 23. The staining analysis device further comprises a sliding drive mechanism, which is used to drive the slide 24 to slide, so that the plurality of pushers 241 push two adjacent sliding racks 222 to slide out of the staining bracket 2 in opposite directions, and the plurality of toggles 242 toggles the plurality of placement racks 23 to swing angles; A flushing assembly 53 is also provided in the housing 1 , and the flushing assembly 53 is used to flush water onto the slices 31 .

[0038] It should be noted that a plurality of sliding openings are provided on the dyeing bracket 2, and a plurality of sliding frames 222 are slidably arranged in the corresponding sliding openings, and balls can be arranged on both sides of the sliding frames 222. The rolling contact between the balls and the inner wall of the sliding opening reduces the friction force when the sliding frames 222 slide, thereby facilitating the sliding of the sliding frames 222. The bracket driving mechanism 4 may include a linear motor and a pneumatic clamping structure, which clamps the dyeing bracket 2 by the pneumatic clamping structure, and drives the dyeing bracket 2 to move into the dye box 111 or the flushing box 112 by the linear motor to achieve dyeing and flushing of the slices 31. The sliding driving mechanism can use a cylinder to drive the slide 24 to slide, so that when the cylinder drives the slide 24 to move, it drives the pushing member 241 and the toggle member 242 to move synchronously.

[0039] The push member 241 is a push shaft, and the bottom of the plurality of sliding frames 222 is provided with a guide opening 2221, the guide opening 2221 is inclined, and the push member 241 is movably connected in the guide opening 2221. Fig.10, the direction of arrow a is the moving direction of the pushing member 241, the direction of arrow b is the moving direction of the two sliding racks 222, and the inclination directions of the guide openings 2221 opened at the bottom of the two adjacent sliding racks 222 are opposite. When the slide 24 moves to drive the pushing member 241 to move, the two pushing members 241 can move in the corresponding guide openings 2221, so that the two pushing members 241 can push the two sliding racks 222 to move in opposite directions and extend the two sliding racks 222 out of the staining tray 2, so that the slices 31 on the sliding rack 222 can be pushed out of the staining tray 2.

[0040] The rack 23 is fixedly provided with a rubber pad 231, which is used to fix the glass slide 3 on the rack 23. When placing the glass slide 3, the glass slide 3 can be placed in the rubber pad 231 and fixed by the rubber pad 231. The toggle member 242 is a toggle shaft. The sides of the racks 23 are provided with side holes 232. The toggle member 242 is movably arranged in the side holes 232. Fig.11 , wherein the direction of arrow c is the moving direction of the toggle member 242, and the direction of arrow d is the swinging direction of the placement rack 23. That is, when the slide 24 moves to drive the toggle member 242 to move, since the placement rack 23 is hinged and the toggle member 242 is movably arranged in the side hole 232, the placement rack 23 can be swung by the toggle member 242 during the movement of the toggle member 242, so that the slide 3 set on the placement rack 23 can be synchronously swung.

[0041] It should be noted that the side hole 232 is opened through the placement rack 23, and the toggle member 242 is also set through the side hole 232, so that when the two adjacent sliding racks 222 slide out of the dyeing bracket 2, their toggle members 242 can still be in the side hole 232, thereby ensuring that after the sliding rack 222 slides out of the dyeing bracket 2, the toggle member 242 can still toggle the placement rack 23 to a swing angle.

[0042] In this embodiment, the real-time scene is specifically as follows: first, a plurality of glass slides 3 with slices 31 fixed on their surfaces are placed in corresponding placement racks 23, and the glass slides 3 are fixed on the placement racks 23 by means of rubber pads 231 provided on the placement racks 23, and then the staining tray 2 is placed in the dye box 111 for staining by means of the tray driving mechanism 4. After staining, the staining tray 2 is placed in the rinse box 112 by means of the tray driving mechanism 4, and then the slide 24 is driven by the sliding driving mechanism to slide in the staining tray 2, so that the slide 24 drives the pushing member 241 and the toggle member 242 to move synchronously, so that the plurality of pushing members 241 can push two adjacent sliding racks 222 to move in opposite directions, and slide out the staining tray 2, and make the glass slides 3 placed on the corresponding sliding racks 222 extend out of the staining tray 2, and at the same time, the plurality of placement racks 23 are toggled by means of the plurality of toggle members 242 to swing at different angles, so that the glass slides 3 placed on the placement racks 23 can be synchronously swung at different angles, and the staining tray 2 can be unfolded, as shown in FIG. Figure 5 The figure shows a schematic diagram of the state of the staining bracket 2 after it is unfolded. At this time, after the placement rack 23 is moved, the glass slide 3 is in a tilted state, and the movement of the two adjacent sliding racks 222 drives the corresponding glass slide 3 to extend out of the staining bracket 2, so that the distance between the two glass slides 3 in the same horizontal direction can be increased. Due to the increase in the distance, the slice 31 on the surface of the glass slide 3 can be exposed when the glass slide 3 is tilted, so that it is easy to observe the direction of the water flow and the degree of flushing during the flushing process, which is convenient for controlling the staining effect during the water washing process, and finally the slice 31 can be flushed through the flushing component 53.

[0043] It should also be noted that since the staining tray 2 is unfolded and the slide 3 is tilted, when the slice 31 is rinsed, the water flows down along the inclined surface, reducing excessive scouring of a certain part of the surface of the slice 31 and avoiding excessive loss of dye in the local area. The inclined placement allows the water to clean the surface of the slice 31 more evenly, which helps to maintain the overall staining balance of the slice 31.

[0044] For details, please refer to the attached manual. Fig.12 and Fig.13 as well as Fig.17The present invention provides a specific structure of a sliding drive mechanism, the sliding drive mechanism is a sliding drive component 25, the sliding drive component 25 includes a stopper 251, the stopper 251 is fixedly arranged on the bottom inner wall of the washing box 112, and the top of the stopper 251 is inclined, the bottom of the dyeing bracket 2 is provided with an opening 252, the bottom of the slide 24 is provided with an abutting groove 253, the top inner wall of the abutting groove 253 is inclined, and the top of the stopper 251 and the top inner wall of the abutting groove 253 have the same inclination angle, an elastic member 254 is fixedly arranged on one side of the slide 24, and the end of the elastic member 254 away from the slide 24 is fixedly arranged on the dyeing bracket 2, and a slide rod 255 is fixedly arranged on the other side of the slide 24, the slide rod 255 is slidably arranged in the dyeing bracket 2, and a limit block 256 is fixedly arranged on the slide rod 255, and the limit block 256 is movably abutted with the dyeing bracket 2.

[0045] It should be noted that, by arranging a stopper 251 on the bottom inner wall of the flushing box 112, when the dyeing tray 2 is placed in the flushing box 112, the stopper 251 can be extended into the abutment groove 253 through the opening 252, that is, through the stopper 251 with the inclined top and the abutment groove 253 with the inclined top inner wall, when the dyeing tray 2 is placed in the flushing box 112, the stopper 251 pushes the slide 24 to slide, so that the dyeing tray 2 can be unfolded when the slide 24 is pushed, and then the slice 31 placed on the dyeing tray 2 can be directly rinsed, and during the rinsing process, the unfolded dyeing tray 2 can be used to observe the effect of the water flow direction and the degree of rinsing, so as to control the dyeing effect during the water washing process, and at the same time, the slice 31 can be placed in an inclined state, thereby reducing excessive scouring of a certain part of the surface of the slice 31, avoiding excessive loss of dye in the local area, and ensuring uniform scouring of the surface of the slice 31, which helps to maintain the overall dyeing balance of the slice 31.

[0046] It should also be noted that, through the above structure and through the elastic member 254, which can be a spring, the dyeing bracket 2 can be automatically retracted when the dyeing bracket 2 is taken out of the flushing box 112, so that the dyeing bracket 2 can be placed in the dye box 111 for further dyeing.

[0047] It should be further explained that the staining process of the slices 31 also includes soaking in anhydrous ethanol of various concentrations, so it is necessary to set up multiple soaking pools in the casing 1, and the multiple soaking pools respectively contain anhydrous ethanol of different concentrations. In order to save the placement space in the casing 1 and improve the utilization rate, the size of the soaking pool and the dye box 111 are smaller than the flushing box 112. Therefore, it is necessary to dye multiple slices 31 at the same time and save flushing time. While ensuring the staining efficiency, it is necessary to set the staining bracket 2 to be expandable. When flushing the slices 31, the staining bracket 2 is in an expanded state in the flushing box 112 to observe the effect of the water flow direction and the flushing degree.

[0048] For details, please refer to the attached manual. Fig.14 and Fig.18 The present invention also provides another specific structure of the sliding drive mechanism, the sliding drive mechanism is a sliding drive assembly 6, the sliding drive assembly 6 includes a driving member 61, the driving member 61 is fixedly mounted on the dye box 111, the output end of the driving member 61 extends into the dye box 111, and a push rod 62 is fixedly arranged, and an elastic member 63 and a sliding rod 64 are fixedly arranged on both sides of the slide seat 24, respectively. The sliding rod 64 is slidably arranged in the dyeing bracket 2, and a limiting block 65 is fixedly arranged on the sliding rod 64. The limiting block 65 is movably abutted against the dyeing bracket 2, and a bottom groove 641 is opened at the bottom of the sliding rod 64, and the push rod 62 is located in the bottom groove 641, and the push rod 62 is movably abutted against the inner wall of the bottom groove 641.

[0049] It should be noted that a driving member 61 can be installed on the sides of the dye box 111 and the flushing box 112. The driving member 61 is a cylinder. After the dyeing tray 2 is placed in the flushing box 112, the push rod 62 is driven by the cylinder to move, and after the push rod 62 moves to contact the inner wall of the bottom groove 641, the push rod 62 is continued to be driven to move, so that the push rod 62 pushes the slide 24 to move, and the slide 24 can be driven to move until the dyeing tray 2 is unfolded.

[0050] It should also be noted that after the staining bracket 2 is placed in the dye box 111, the push rod 62 is driven by the cylinder to move. When the push rod 62 moves to contact the inner wall of the bottom groove 641, the push rod 62 is driven by the cylinder to telescope and move. The telescopic movement distance can be determined according to the required swing amplitude of the glass slide 3, and the elastic member 63 is a spring so that with the cooperation of the elastic member 63, the effect of pushing the slide 24 to reciprocate can be achieved. Therefore, when the slide 24 reciprocates, the slide 3 can be driven to swing back and forth by the toggle member 242, and the slice 31 can be driven to shake slightly by the slide 3, so as to help the dye to cover the surface of the slice 31 more evenly, ensure that the dye can be evenly distributed, thereby improving the consistency of dyeing, and can increase the contact time between the dye and the slice 31, so that the dye can better penetrate into the cell, thereby improving the staining intensity of the cell nucleus and cytoplasm, and can also help eliminate In order to remove bubbles and ensure that the dye can evenly contact the slice 31, local uneven dyeing caused by bubbles is avoided. However, while the slide 3 is swung by the toggle member 242, the pusher 241 will also push the two adjacent sliding racks 222 to slide out of the dyeing bracket 2, which will cause the slice 31 on the sliding rack 222 to increase a lateral movement. In order to avoid the slice 31 from swinging and also having a lateral reciprocating movement, which disrupts the flow of the dye and affects the dyeing, it is necessary to set the diameter of the guide port 2221 to be larger than the diameter of the pusher 241, and it is necessary to ensure that during the reciprocating motion of the slide 24, its movement distance will not cause the effect of the pusher 241 pushing the slide 222 to move. The specific movement distance of the slide 24, as well as the diameters of the guide port 2221 and the pusher 241 can be set according to actual conditions and will not be described in detail here.

[0051] It is also necessary to further explain that the bottom inner walls of the dye box 111 and the flushing box 112 are both provided with positioning seats, and the bottom of the dyeing tray 2 is provided with a positioning block. After the dyeing tray 2 is placed in the dye box 111 or the flushing box 112, the positioning block can be inserted into the positioning seat to achieve the positioning of the dyeing tray 2.

[0052] For further information, please refer to the attached manual. Figure 2 The bracket driving mechanism 4 includes a linear driving component 1 41, a linear driving component 2 42 and a clamping component 43. The clamping component 43 is used to clamp the dyeing bracket 2. The linear driving component 2 42 is installed at the output end of the linear driving component 1 41. The clamping component 43 is installed at the output end of the linear driving component 2 42. The linear driving component 2 42 is used to drive the dyeing bracket 2 to move vertically linearly, and the linear driving component 1 41 is used to drive the dyeing bracket 2 to move horizontally linearly.

[0053] It should be noted that both the linear drive component 1 41 and the linear drive component 2 42 are linear motors, and their clamping component 43 is installed at the output end of the linear drive component 2 42 . After the dyeing bracket 2 is clamped by the clamping component 43 , the linear drive component 1 41 and the linear drive component 2 42 can drive the dyeing bracket 2 to move.

[0054] For further information, please refer to the attached manual. Fig.15 The clamping assembly 43 includes a shell 431, which is fixedly mounted on the output end of the linear drive assembly 42. A power component 432 is installed in the shell 431, and a gear 433 is installed at the output end of the power component 432. Two racks 434 are slidably arranged in the shell 431, and the adjacent sides of the two racks 434 are meshed with the gear 433, and clamp seats 435 are fixedly arranged on the two racks 434, and positioning shafts 436 are installed on the two clamp seats 435. A top frame 21 is installed on the dyeing bracket 2, and a positioning hole 211 is opened on the top frame 21, and the positioning shaft 436 is adapted to the positioning hole 211.

[0055] It should be noted that the power component 432 is a motor, which drives the gear 433 to rotate, and drives the two clamping seats 435 to move closer to clamp the top frame 21 through the two racks 434, and at the same time inserts the positioning shaft 436 into the positioning hole 211 to achieve the clamping and fixing of the dyeing bracket 2.

[0056] For further information, please refer to the attached manual. Fig.16 A mobile flushing mechanism 5 is also provided in the casing 1, and the mobile flushing mechanism 5 includes a linear drive component three 51 and a linear drive component four 52. The linear drive component four 52 is installed at the output end of the linear drive component three 51, and the flushing component 53 is installed at the output end of the linear drive component four 52. The linear drive component three 51 is used to drive the flushing component 53 to move horizontally and linearly left and right, and the linear drive component four 52 is used to drive the flushing component 53 to move horizontally and linearly forward and backward.

[0057] It should be noted that the linear drive component three 51 and the linear drive component four 52 are both linear motors, which drive the flushing component 53 to move linearly in the housing 1 through the linear drive component three 51 and the linear drive component four 52 to adjust the position of the flushing component 53 to achieve its flushing work.

[0058] For further information, please refer to the attached manual. Fig.16 The flushing component 53 includes a water pump 531, which is installed at the output end of the linear drive component 52. A flushing pipe 532 is installed at the water outlet end of the water pump 531, and the output end of the flushing pipe 532 points to the slice 31.

[0059] It should be noted that the water inlet end of the water pump 531 is connected to a water pipe, and the water inlet end of the water pipe can be connected to a water tank containing distilled water. During flushing, distilled water is drawn by the water pump 531 and flushed toward the slices 31 through the flushing pipe 532. While flushing, the flushing component 53 is driven to move by the linear drive component three 51 and the linear drive component four 52 of the linear motor to achieve uniform flushing of the slices 31 on the unfolded staining bracket 2.

[0060] The above-mentioned embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the present invention. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention.

Claims

1. A staining analysis device for pathological diagnosis, characterized in that: include: A housing, a dyeing bracket, a sliding drive mechanism and a flushing assembly, wherein the housing is provided with a plurality of dyeing pools, the dyeing pools include a dye liquid box and a flushing box, and the housing is also provided with a bracket drive mechanism for driving the dyeing bracket to move; The staining bracket is provided with multiple groups of supporting components, and the supporting components include a fixed frame and two sliding frames, the fixed frame is fixedly arranged on the staining bracket, the sliding frame is slidably arranged on the staining bracket, and the fixed frame and the sliding frame are both hingedly provided with a placement frame for placing a slide glass; A plurality of pushers and toggle members are slidably arranged in the dyeing bracket, and the sliding drive mechanism is used to drive the pushers and toggle members to slide, so that the plurality of pushers push two adjacent sliding racks to slide out of the dyeing bracket in opposite directions, and the plurality of toggle members toggle the plurality of placement racks to swing angles.

2. A staining analysis device for pathological diagnosis according to claim 1, characterized in that: A slide seat is slidably arranged in the dyeing bracket, and a plurality of pushers and toggle members are fixedly arranged on the slide seat. A guide opening is provided at the bottom of a plurality of sliding frames, and the guide opening is inclined. The pusher is movably connected in the guide opening, and the inclination directions of the guide openings provided at the bottom of two adjacent sliding frames are opposite.

3. A staining analysis device for pathological diagnosis according to claim 2, characterized in that: A rubber pad is fixedly arranged on the placement rack, and the rubber pad is used to fix the slide on the placement rack. Side holes are opened on the sides of the plurality of placement racks, and the toggle member is movably arranged in the side holes.

4. A staining analysis device for pathological diagnosis according to claim 3, characterized in that: The sliding drive mechanism is a sliding drive component 1, and the sliding drive component 1 includes a stop block, which is fixedly arranged on the bottom inner wall of the washing box, and the top of the stop block is inclined. The bottom of the dyeing bracket is provided with an opening, and the bottom of the slide seat is provided with an abutment groove, the top inner wall of the abutment groove is inclined, and the top of the stop block and the top inner wall of the abutment groove have the same inclination angle, and an elastic member 1 is fixedly arranged on one side of the slide seat, and the end of the elastic member 1 away from the slide seat is fixedly arranged on the dyeing bracket.

5. A staining analysis device for pathological diagnosis according to claim 4, characterized in that: A slide rod 1 is fixedly arranged on the other side of the slide seat, and the slide rod 1 is slidably arranged in the dyeing bracket, and a limit block 1 is fixedly arranged on the slide rod 1, and the limit block 1 is movably abutted against the dyeing bracket.

6. A staining analysis device for pathological diagnosis according to claim 3, characterized in that: The sliding drive mechanism is a sliding drive component 2, and the sliding drive component 2 includes a driving member, and the driving member is fixedly installed on the dye liquid box. The output end of the driving member extends into the dye liquid box and is fixedly provided with a push rod. Two elastic members and two slide rods are fixedly provided on both sides of the slide seat respectively. The two slide rods are slidably set in the dyeing bracket. Two limit blocks are fixedly provided on the two slide rods. The two limit blocks are movably abutted against the dyeing bracket, and a bottom groove is opened at the bottom of the two slide rods. The push rod is located in the bottom groove, and the push rod is movably abutted against the inner wall of the bottom groove.

7. A staining analysis device for pathological diagnosis according to claim 5 or 6, characterized in that: The bracket driving mechanism includes a linear drive component 1, a linear drive component 2 and a clamping component, the clamping component is used to clamp the dyeing bracket, the linear drive component 2 is installed at the output end of the linear drive component 1, and the clamping component is installed at the output end of the linear drive component 2. The linear drive component 2 is used to drive the dyeing bracket to move vertically linearly, and the linear drive component 1 is used to drive the dyeing bracket to move horizontally linearly.

8. A staining analysis device for pathological diagnosis according to claim 7, characterized in that: The clamping assembly includes a shell, which is fixedly installed on the output end of the linear drive assembly 2. A power component is installed in the shell, and a gear is installed on the output end of the power component. Two racks are slidably arranged in the shell, and the sides of the two racks that are close to each other are meshed with the gears. Clamp seats are fixedly arranged on the two racks, and positioning shafts are installed on the two clamp seats. A top frame is installed on the dyeing bracket, and a positioning hole is opened on the top frame. The positioning shaft is adapted to the positioning hole.

9. A staining analysis device for pathological diagnosis according to claim 8, characterized in that: A mobile flushing mechanism is also provided in the casing, and the mobile flushing mechanism includes a linear drive component three and a linear drive component four. The linear drive component four is installed at the output end of the linear drive component three, and the flushing component is installed at the output end of the linear drive component four. The linear drive component three is used to drive the flushing component to move horizontally and linearly to the left and right, and the linear drive component four is used to drive the flushing component to move horizontally and linearly to the front and back.

10. A staining analysis device for pathological diagnosis according to claim 9, characterized in that: The flushing component includes a water pump, which is installed at the output end of the linear drive component four. A flushing pipe is installed at the water outlet end of the water pump, and the output end of the flushing pipe points to the slice.

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