Urine Analyzer and Its Control Method

Abstract

The present invention discloses a urine analyzer and its control method, including the steps: S1: The rotary cutting valve is switched to the sample flow channel, and the sample in the sample collection cavity is inhaled into the transfer channel. S2: The transfer channel is communicated with the detection flow channel, and the water in the clean water collection cavity is driven to flow into the common flow channel and the transfer channel, and the water in the transfer channel is mixed with the sample in the transfer channel. S3: The rotary cutting valve is switched to the detection flow channel, and the mixed sample and water in the transfer channel are discharged. S4: The water in the common flow channel is pushed into the detection cavity for detection. S5: The rotary cutting valve is switched to the sample flow channel, and a quantitative sample is extracted into the transfer channel. S6: The rotary cutting valve is switched to the reagent flow channel, the transfer channel is communicated with the reagent flow channel, and a quantitative reagent in the reagent cavity is sucked into the transfer channel. S7: The rotary cutting valve is switched to the detection flow channel, and the reagent and sample in the transfer channel are pushed into the detection cavity. S8: The detector starts to detect and will detect. S9: The water in the common flow channel is pushed into the detection flow channel and discharged from the detection cavity.

Description

Technical Field

[0001] The present invention relates to the technical field of urine analyzers, and particularly relates to a urine analyzer and a control method thereof. Background Art

[0002] With the increase of human lifespan, the importance of healthcare and maintenance has received more and more attention. Urine can reflect a person's health condition to a certain extent. By quantitatively analyzing the urine components, diseases such as pancreas and kidney diseases can be understood. Urine analysis is an important indicator for detecting a person's physical condition. Usually, pH, protein, occult blood, specific gravity, glucose, ketone body, urobilinogen, nitrate, white blood cell, bilirubin, and vitamin C can be detected to reflect a series of indicators of the body. Usually, urine tests are carried out in hospitals. Due to the shortage of medical resources, after the examinees arrive at the hospital, they often have to queue up for registration, seeing a doctor, paying fees, collecting urine, waiting for batch urine tests, and then queuing up to get the results, which is time-consuming and laborious.

[0003] Currently, urine analyzers for home use appear on the market, which cannot accurately and quantitatively extract samples and reagents, and have a slow operation time and poor experience. Summary of the Invention

[0004] The purpose of the present invention is to provide a urine analyzer and a control method thereof to solve the problems of the prior art.

[0005] To solve the above technical problems, an embodiment of the present invention provides a urine analyzer, which includes:

[0006] A reagent kit, which is provided with a plurality of reagent chambers, and reagents are placed in the reagent chambers;

[0007] A collector, which is provided with a sample collection chamber and a clean water collection chamber;

[0008] A rotary cutting valve, which is provided with a common flow channel, a sample flow channel, a plurality of reagent flow channels, a detection flow channel, an air flow channel, and a transfer channel; the sample flow channel is communicated with the sample collection chamber through a lower sample pipeline; the common flow channel is communicated with the clean water collection chamber; the plurality of reagent flow channels are respectively communicated with the plurality of reagent chambers; one end of the transfer channel is communicated with the inner end of the common flow channel, and the other end is operably communicated with the sample flow channel, the plurality of reagent flow channels, the detection flow channel, and the air flow channel;

[0009] A detection mechanism, which is provided with a detector and a detection chamber inside, and the detection chamber is communicated with the detection flow channel.

[0010] The present invention designs a control method for a urine analyzer, which applies the above urine analyzer, and includes the steps:

[0011] S1: The rotary valve switches to the sample flow path, sucking the sample in the sample collection chamber into the transfer channel;

[0012] S2: The rotary valve switches to the detection flow path, the transfer channel is communicated with the detection flow path, driving the water in the clean water collection chamber to flow into the common flow path and the transfer channel, and the water in the transfer channel is mixed with the sample in the transfer channel;

[0013] S3: The rotary valve switches to the detection flow path, discharging the mixed sample and water in the transfer channel;

[0014] S4: Pushing the water in the common flow path into the detection chamber for detection;

[0015] S5: The rotary valve switches to the sample flow path, quantitatively extracting the sample into the transfer channel;

[0016] S6: The rotary valve switches to the reagent flow path, the transfer channel is communicated with the reagent flow path, quantitatively sucking the reagent in the reagent chamber into the transfer channel;

[0017] S7: The rotary valve switches to the detection flow path, pushing the reagent and the sample in the transfer channel into the detection chamber;

[0018] S8: The detector starts to detect;

[0019] S9: Pushing the water in the common flow path into the detection flow path and discharging it from the detection chamber.

[0020] In one embodiment, the sample flow path includes:

[0021] A lower sample flow path, the lower sample flow path is communicated with the sample collection chamber through a lower sample pipe and is provided with a sample burette; and

[0022] An upper sample flow path, the upper sample flow path is communicated with the sample burette;

[0023] Step S1 includes:

[0024] S1.1: The rotary valve switches to the upper sample flow path, the transfer channel is communicated with the upper sample flow path, sucking the air in the upper sample flow path and the sample burette, a negative pressure is formed in the sample burette, and the sample in the sample collection chamber flows into the sample burette;

[0025] S1.2: Switch the rotary valve to make the transfer channel communicate with the lower sample flow path, driving the sample in the sample burette to flow into the transfer channel.

[0026] In one embodiment, the urine analyzer further includes:

[0027] A first pump, the first pump being connected to two pipelines, one of the pipelines being in communication with the fresh water collection chamber; and

[0028] A second pump, the second pump being connected to another pipeline and a driving pipeline, the driving pipeline being in communication with the common flow channel;

[0029] In step S1.1, the first pump is started to extract the air in the upper sample flow channel and the sample burette;

[0030] In step S1.2, the first pump is started to suck the sample in the sample burette into the transfer channel;

[0031] In step S2, the first pump is started to pump the water in the fresh water collection chamber into the common flow channel and the transfer channel;

[0032] In step S3: The rotary cutting valve is switched to the air flow channel, the transfer channel is in communication with the air flow channel, after the control module controls the second pump to start sucking air, the rotary cutting valve is switched to the detection flow channel, and the second pump is started to discharge the mixed sample and water in the transfer channel from the detection flow channel and the detection chamber;

[0033] In step S4, the first pump is started to push the water in the common flow channel into the detection flow channel; then the rotary cutting valve is switched to the air flow channel, the second pump is started and a fixed amount of air is sucked into the transfer channel, the rotary cutting valve is switched to the detection flow channel again, and the second pump is started to push the water in the detection flow channel into the detection chamber for detection;

[0034] In step S5, the second pump is started to quantitatively extract the sample into the transfer channel;

[0035] In step S6, the second pump is started and a fixed amount of the reagent in the reagent chamber is sucked into the transfer channel;

[0036] In step S7, the second pump is started and the reagent and the sample in the transfer channel are pushed into the detection chamber;

[0037] In step S9, the rotary cutting valve is switched to the detection flow channel, the first pump is started and the water in the common flow channel is pushed into the detection flow channel and discharged from the detection chamber.

[0038] In one embodiment, in step S5, first determine whether the sample needs to be diluted;

[0039] If dilution is required, the rotary cutting valve first switches to the detection flow channel, and the first pump is started to push a fixed amount of clear water into the detection flow channel. Then the rotary cutting valve switches to the air flow channel, and the second pump is started to suck a fixed amount of air into the transfer channel. After the rotary cutting valve switches to the detection flow channel again, the second pump is started to suck the clear water in the detection flow channel into the transfer channel. The rotary cutting valve switches to the lower sample flow channel, the second pump is started, and a sample in the lower sample flow channel is quantitatively extracted into the transfer channel to be mixed with the water in the transfer channel. Then the rotary cutting valve switches to the air flow channel, and the second pump is started again to suck a fixed amount of air into the transfer channel. The rotary cutting valve switches to the detection flow channel, and the second pump is started to push the diluted sample into the transfer channel.

[0040] The second pump is started to absorb a fixed amount of diluted sample from the detection flow channel into the transfer channel. Then the rotary cutting valve switches to the air flow channel again to absorb a fixed amount of air into the transfer channel. The rotary cutting valve switches to the detection flow channel again, and the second pump is started to push the air absorbed by the transfer channel into the detection flow channel.

[0041] If dilution is not required, the rotary cutting valve switches to the air flow channel, first quantitatively sucks air, and then the rotary cutting valve switches to the lower sample flow channel, and the second pump is started to quantitatively extract the sample into the transfer channel.

[0042] In one embodiment, it is judged whether multiple reagents need to be extracted. If one reagent needs to be extracted, step S7 is carried out after step S6. If multiple reagents need to be extracted, step S6 is repeated multiple times. After each extraction of the reagent, the rotary cutting valve also needs to be switched to the detection flow channel, and after the reagent is pushed into the detection flow channel, the rotary cutting valve is switched to different reagent flow channels to extract the reagent again.

[0043] In one embodiment, the rotary cutting valve is provided with a mixing cavity, and the mixing cavity is located on the path of the detection flow channel and communicates with the detection flow channel.

[0044] In step S8, after the rotary cutting valve switches to the detection flow channel, the second pump is started to first push the reagent and the sample in the transfer channel into the mixing cavity to be mixed into a mixed liquid, and then the second pump is started to push the mixed liquid into the detection cavity.

[0045] In one embodiment, in step S8, the second pump is started for a preset time and then reset for the preset time. After the reagent and the sample in the mixing cavity are mixed into the mixed liquid, the second pump then pushes the mixed liquid into the detection cavity.

[0046] In one embodiment, the mixing chamber includes a mixing bend and at least one mixing chamber that communicate with each other, and the mixing bend is a curved flow channel;

[0047] In step S8, the second pump is started for a preset time and then reset for a preset time. After the reagent and the sample are continuously flowed and mixed in the mixing bend and the mixing chamber to form a mixed liquid, the second pump is reset and then the mixed liquid is pushed into the detection chamber.

[0048] In one embodiment, in step S8, after the second pump is reset and the reagent and the sample in the transfer channel are pushed into the mixing chamber to form the mixed liquid, the rotary cutting valve is switched to the air flow channel, the second pump is started and quantitatively extracts air into the transfer channel, and then the rotary cutting valve is switched to the detection flow channel again, and the second pump is reset to push the mixed liquid in the mixing chamber into the detection chamber.

[0049] In one embodiment, in step S9, the first pump is started and the water in the common flow channel is pushed into the detection flow channel, and is mixed with the sample and the reagent in the detection chamber to form waste liquid; the rotary cutting valve is switched to the air flow channel, the second pump is started, air is sucked into the transfer channel, and then the rotary cutting valve is switched to the detection flow channel again, and the second pump is reset to discharge the waste liquid in the detection chamber.

[0050] In one embodiment, after step S9, step S10 is further included: the first pump is started, the water in the common flow channel is pushed into the detection flow channel, and is discharged from the detection chamber;

[0051] Then the rotary cutting valve is switched to the lower sample flow channel, the first pump is started, the water in the common flow channel is pushed into the sample collection chamber from the lower sample flow channel, and is discharged from the sample collection chamber; or

[0052] After step S9, step S10 is further included: the rotary cutting valve is switched to the lower sample flow channel, the first pump is started, the water in the common flow channel is pushed into the sample collection chamber from the lower sample flow channel, and is discharged from the sample collection chamber;

[0053] The first pump is started, the water in the common flow channel is pushed into the detection flow channel, and is discharged from the detection chamber.

[0054] In one embodiment, after step S10, step S11 is further included: the rotary cutting valve is switched to the detection flow channel, the first pump is started, and all the remaining water in the common flow channel is pushed into the detection flow channel, and is discharged from the detection chamber.

[0055] In one embodiment, a first sensor is provided in the sample burette;

[0056] The urine analyzer further includes a control module, which is connected to the first pump, the second pump, the rotary valve, and the first sensor;

[0057] Before step S2, it further includes the step of: the first sensor sends the sample volume information sensed in the sample burette to the control module. If the sample volume information does not meet the requirements, the process ends; if it meets the requirements, then step S2 is executed;

[0058] In step S8, after the detector detects, it sends the detection result to the control module.

[0059] In one embodiment, after step S9, if the detection result is abnormal, steps S1 to S9 are repeatedly executed; if the detection result is normal, the next detection item is carried out.

[0060] In one embodiment, the urine analyzer further includes a warning light, which is electrically connected to the control module;

[0061] After step S9, if the detection results are abnormal for two consecutive times, the control module controls the warning light to give a warning.

[0062] In one embodiment, a second sensor connected to the control module is provided in the clean water collection chamber;

[0063] Before step S3, it further includes the step of: the second sensor sends the amount of clean water detected in the clean water collection chamber to the control module. If it does not meet the requirements, the control module controls the process to end; if it meets the requirements, then step S4 is carried out.

[0064] In one embodiment, the rotary valve is further provided with a washing flow channel;

[0065] The urine analyzer further includes a washing liquid and a washing chamber for containing the washing liquid;

[0066] After steps S1 to S9 are cycled a preset number of times and the reagent kit needs to be replaced, it further includes the steps:

[0067] S01: The rotary valve switches to the detection flow channel, and the first pump starts to push the water in the clean water collection chamber into the transfer channel and then into the detection flow channel in sequence through the common flow channel;

[0068] S02: The rotary valve switches to the air flow channel, and the second pump or the first pump starts and absorbs air into the transfer channel;

[0069] S03: The rotary valve switches to the washing flow channel, and the second pump starts and sucks a fixed amount of washing liquid into the transfer channel;

[0070] S04: The rotary valve switches to the detection flow path again. The second pump resets and pushes the washing liquid in the transfer channel into the detection flow path, where it is mixed with the water in the detection flow path to form a diluted washing liquid. Then the first pump starts and sucks the diluted washing liquid in the detection flow path into the transfer channel.

[0071] S05: The rotary valve switches to one of the reagent flow paths. The first pump starts and pushes the diluted washing liquid in the transfer channel into the reagent flow path and the reagent chamber. The rotary valve sequentially switches to multiple reagent flow paths, and the first pump starts and sequentially pushes the diluted washing liquid in the transfer channel into multiple reagent chambers.

[0072] S06: The rotary valve sequentially switches to multiple reagent flow paths. The first pump starts and sequentially pushes the clear water in the common flow path into multiple reagent flow paths and multiple reagent chambers.

[0073] S07: Replace with a new reagent kit.

[0074] In one embodiment, the rotary valve is provided with a mixing chamber, which is located on the path of the detection flow path and communicates with the detection flow path.

[0075] Step S01: The rotary valve switches to the detection flow path. The first pump starts and pushes the water in the clear water collection chamber into the transfer channel and then into the mixing chamber in sequence from the common flow path.

[0076] Step S04: The rotary valve switches to the detection flow path again. The second pump resets and pushes the washing liquid in the transfer channel into the detection flow path and then into the mixing chamber. The first pump rotates forward for a preset time and then rotates backward for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid. Then the first pump starts and sucks the diluted washing liquid in the detection flow path into the transfer channel.

[0077] In one embodiment, the rotary valve is further provided with a washing flow path.

[0078] The urine analyzer further includes a washing liquid and a washing chamber for holding the washing liquid.

[0079] After steps S1 to S9 operate in a loop for a preset number of times, the urine analyzer is regularly cleaned, including the steps:

[0080] S001: The rotary valve switches to the detection flow path. The first pump starts and pushes the water in the clear water collection chamber into the transfer channel and then into the detection flow path in sequence from the common flow path.

[0081] S002: The rotary valve switches to the air flow channel, and the second pump or the first pump starts and sucks air into the transfer channel;

[0082] S003: The rotary valve switches to the washing flow channel, the second pump starts, and sucks a fixed amount of washing liquid into the transfer channel;

[0083] S004: The rotary valve switches to the detection flow channel again, the second pump resets and pushes the washing liquid in the transfer channel into the detection flow channel and mixes it with the water in the detection flow channel to form a diluted washing liquid;

[0084] S005: The first pump starts and sucks the diluted washing liquid in the detection flow channel into the transfer channel;

[0085] S005: The rotary valve switches to the lower sample flow channel, the first pump starts, and pushes the diluted washing liquid in the transfer channel into the sample collection cavity;

[0086] S006: Repeat steps S001 to S004, the first pump starts, and pushes the diluted washing liquid in the detection flow channel into the detection cavity;

[0087] S007: After waiting for a preset time, the rotary valve first switches to the lower sample flow channel, the first pump starts, and pushes the water in the common flow channel into the sample collection cavity and then discharges it. Then the rotary valve switches to the detection flow channel, the first pump starts, and pushes the water in the common flow channel into the detection cavity and then discharges it; or

[0088] After waiting for a preset time, then the rotary valve switches to the detection flow channel, the first pump starts, and after pushing the water in the common flow channel into the detection cavity and discharging it, the rotary valve switches to the lower sample flow channel again, the first pump starts, and pushes the water in the common flow channel into the sample collection cavity and then discharges it.

[0089] In one embodiment, the rotary valve is provided with a mixing cavity, and the mixing cavity is located on the path of the detection flow channel and communicates with the detection flow channel;

[0090] Step S001: The rotary valve switches to the detection flow channel, the first pump starts, and pushes the water in the clean water collection cavity into the transfer channel and then into the mixing cavity in sequence from the common flow channel;

[0091] Step S004: The rotary valve switches to the detection flow path again. The second pump resets and pushes the washing liquid in the transfer channel into the mixing chamber. The first pump rotates forward for a preset time and then rotates backward for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid. Then, the first pump starts and pumps the diluted washing liquid in the detection flow path into the transfer channel.

[0092] In one embodiment, the rotary valve includes:

[0093] A microfluidic chip, which is provided with the common flow path, the lower sample flow path, the upper sample flow path, the clean water flow path, a plurality of reagent flow paths, the detection flow path, and the air flow path; and

[0094] A rotor, which is rotatably connected to the microfluidic chip and is provided with the transfer channel. The inner end of the transfer channel communicates with the common flow path, and the outer end rotates with the rotor and communicates with the lower sample flow path, the upper sample flow path, the clean water flow path, a plurality of reagent flow paths, the detection flow path, and the air flow path.

[0095] In one embodiment, the microfluidic chip includes:

[0096] A flow path plate, on the front side of which are provided:

[0097] A central hole, which penetrates the flow path plate and communicates with the inner end of the common flow path; and

[0098] A plurality of circumferential holes, which are arranged around the central hole; and

[0099] A sealing cover plate, which is stacked between the front side of the flow path plate and the rear side of the reagent kit;

[0100] The lower sample flow path, the upper sample flow path, the clean water flow path, a plurality of reagent flow paths, the detection flow path, and the air flow path respectively communicate with the plurality of circumferential holes.

[0101] In one embodiment, the urine analyzer further includes a housing,

[0102] The housing includes a detachable first housing and a second housing;

[0103] The detection mechanism includes a detection plate, on which the detection chamber is provided;

[0104] The reagent kit, the microfluidic chip, and the detection plate are located in the first housing;

[0105] The first pump, the second pump, the rotor, and the detector are located in the second housing. Brief Description of the Drawings

[0106] Figure 1 is a perspective view of a urine analyzer according to an embodiment of the present invention.

[0107] Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 、 Figure 6 、 Figure 7 and Figure 8 are respectively Figure 1 an exploded view of the urine analyzer of the illustrated embodiment.

[0108] Figure 9 is Figures 1 - 8 a perspective view of the locking member in the illustrated embodiment.

[0109] Figure 10 and Figure 11 are respectively Figure 2 a perspective view of the kit in the illustrated embodiment.

[0110] Figure 12 and Figure 13 are respectively Figure 2 a perspective view of the cover plate in the illustrated embodiment.

[0111] Figure 14 is Figure 2 a perspective view of the flow channel plate in the illustrated embodiment.

[0112] Figure 15 is Figure 14 a partial enlarged view of area A of the flow channel plate of

[0113] Figure 16 is Figure 14 a partial enlarged view of area B of the flow channel plate of

[0114] Figure 17 is Figure 2 a perspective view of the flow channel plate in the illustrated embodiment.

[0115] Figure 18 is Figure 4 and Figure 5 a perspective view of the first adapter in the illustrated embodiment.

[0116] Figure 19 is Figure 4 and Figure 5 an assembly view of the kit, the flow channel plate, the cover plate, the first adapter, the rotor and the protective cover in the illustrated embodiment.

[0117] Figure 20 is Figure 1 an exploded view of the first housing in the illustrated embodiment.

[0118] Figure 21 is Figure 2 The perspective view of the detection board in the illustrated embodiment.

[0119] Figure 22 and Figure 23 is Figure 2 The exploded view of the protective cover, rotor, compression spring and convex ring in the illustrated embodiment.

[0120] Figure 24 is Figure 1 The exploded view of the second housing, peristaltic pump, plunger pump and motor in the illustrated embodiment.

[0121] Figure 25 The perspective view of the collector of an embodiment of the present invention.

[0122] Figure 26 and Figure 27 are respectively Figure 25 The exploded view of the collector in the illustrated embodiment.

[0123] Figure 28 The perspective view of the collector of another embodiment of the present invention.

[0124] Figure 29 and Figure 30 are respectively Figure 28 The exploded view of the collector in the illustrated embodiment.

[0125] Figure 31 The flowchart of the control method of the urine analyzer of an embodiment of the present invention.

[0126] Figure 32 The liquid path diagram of the urine analyzer of an embodiment of the present invention. Detailed implementation manners

[0127] To make the objectives, technical solutions and advantages of the present invention clearer, the following will elaborate on each embodiment of the present invention in conjunction with the accompanying drawings. However, those of ordinary skill in the art can understand that in each embodiment of the present invention, many technical details are provided to help readers better understand the present application. However, even without these technical details and various changes and modifications based on the following embodiments, the technical solutions claimed in each claim of the present application can still be implemented.

[0128] Unless the context requires otherwise, throughout the specification and claims, the word "comprising" and its variants, such as "including" and "having", should be understood in an open, inclusive sense, i.e., construed as "including, but not limited to".

[0129] The embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings, so as to more clearly understand the purpose, features and advantages of the present invention. It should be understood that the embodiments shown in the drawings are not a limitation on the scope of the present invention, but only to illustrate the essential spirit of the technical solution of the present invention.

[0130] References to "an embodiment" or "one embodiment" throughout the specification mean that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, appearances of "in an embodiment" or "in one embodiment" throughout the specification need not all refer to the same embodiment. Additionally, the particular features, structures, or characteristics may be combined in any manner in one or more embodiments.

[0131] As used in this specification and the appended claims, the singular forms "a" and "the" include plural referents unless the context clearly dictates otherwise. It should be noted that the term "or" is generally used in its inclusive sense of "and / or" unless the context clearly dictates otherwise.

[0132] In the following description, in order to clearly show the structure and working mode of the present invention, many directional terms will be used for description. However, terms such as "front", "rear", "left", "right", "outer", "inner", "outward", "inward", "up", "down", etc. should be understood as convenient terms and should not be understood as limiting terms.

[0133] The present invention relates to a urine analyzer 100, as Figures 1 - 4 shown, the urine analyzer 100 includes a housing 1, a collector 4, a reagent kit 2 located inside the housing 1, a rotary cutting valve, a pump, and a detection mechanism. The rotary cutting valve includes a microfluidic chip, a rotor 6, and a driving member 93. Among them, the reagent kit 2 is used to hold a variety of reagents. The collector 4 is provided with a collection chamber, and the collection chamber includes a sample collection chamber 411 and a clean water collection chamber 412. The sample collection chamber 411 is used to collect samples, and the clean water collection chamber 412 is used to store water. The flow channel plate 3 is used to provide a plurality of flow channels for the confluence of reagents and samples. As Figure 5 shown, the detection mechanism includes a detector and a detection plate 5. The detection plate 5 is provided with a detection chamber, and the detection chamber is used to receive the samples and reagents from the flow channel plate 3, and the detection chamber is used to detect the samples in the detection chamber. The rotor 6 is used to cooperate with the flow channel plate 3 to facilitate the collection of samples and reagents and push the samples and reagents into the detection mechanism for detection. Figures 22 - 24 The driving member 93 is connected to the rotor 6 and is used to drive the rotor 6 to rotate.

[0134] Specifically, as Figure 1As shown, the housing 1 includes a first housing 11 and a second housing 12. The rear side of the first housing 11 and the front side of the second housing 12 are detachably connected. The "front side" and "front end" of the urine analyzer 100 refer to the side of the first housing 11 away from the second housing 12, and the "rear side" or "rear end" refers to the side of the second housing 12 away from the first housing 11. The kit 2, the rotor 6, and the flow channel plate 3 are located inside the first housing 11, while the pump and the driving member 93 are located inside the second housing 12, and the driving member 93 and the rotor 6 are detachably connected. The driving member 93 and the pump inside the second housing 12 are durable components with a long service life, while the first housing 11 and the kit 2, the rotor 6, and the flow channel plate 3 inside the first housing 11 form a detection device, which is a consumable item. After using it for a period of time, the reagent in the kit 2 is exhausted, and the detection device can be replaced, which can ensure that things are made the best use of and waste is reduced.

[0135] In a specific embodiment, as Figures 4 - 5 shown, the first housing 11 includes a first front cover 111 and a first rear cover 112. The first front cover 111 and the first rear cover 112 are snap-connected or fixedly connected by bolts and form a receiving space. As shown in the figure, the first front cover 111 includes a first front connecting ring 1111 and a first front cover plate 1112 connected to the front end of the first front connecting ring 1111. The first rear cover 112 includes a first rear connecting ring 1121 and a first rear cover plate 1122 connected to the rear end of the first rear connecting ring 1121. The rear end of the first front connecting ring 1111 and the front end of the first rear connecting ring 1121 face each other and are snap-connected and also fixedly connected by bolts. The specific connection method is not limited.

[0136] As Figure 4 shown, the second housing 12 includes a second front cover 121 and a second rear cover 122. The second front cover 121 and the second rear cover 122 are fixedly connected and form another receiving space for accommodating the pump and the driving member 93.

[0137] A recessed mounting groove 1211 is provided at the front end of the second front cover 121. As Figure 2 shown, this mounting groove 1211 is used to accommodate the first rear cover 112.

[0138] In addition, as Figure 8 shown, the urine analyzer 100 further includes two locking members 13. The two locking members 13 are respectively connected to the first rear connecting ring 1121 and are symmetrically arranged on both sides of the first rear connecting ring 1121. The two locking members 13 can detachably connect the first rear cover 112 to the second front cover 121 of the second housing 12.

[0139] Specifically, as Figures 6 - 9As shown, two locking grooves 1212 are provided on the side wall of the installation groove 1211 of the second front cover 121 at intervals. The two locking members 13 respectively include a locking tongue 131, a rotating member 132 and a handle 133. The rotating member 132 is rotatably connected to the first rear cover plate 1122 of the first rear cover 112 through a rotating shaft. The locking tongue 131 is connected to the rear end of the rotating member 132, and the handle 133 is also connected to the front end of the rotating member 132.

[0140] As Figure 7 shown, the first front connecting ring 1111 is provided with a handle avoidance hole 1113. The handle 133 is plate-shaped and its inner end is connected to the front end of the rotating member 132, and its outer end extends to the outside of the first front connecting ring 1111 through the handle avoidance hole 1113. As Figure 2 、 Figure 6 shown, the first rear connecting ring 1121 is provided with a locking tongue avoidance hole 1123. The inner end of the locking tongue 131 is connected to the rotating member, and the outer end extends into the locking groove 1212 through the locking tongue avoidance hole 1123 and is engaged with the locking groove 1212.

[0141] As Figure 2 、 Figure 6 shown, when the first housing 11 needs to be disassembled, by pressing the handle 133 inward into the first housing 11, the rotating member 132 rotates, and the locking tongue 131 can be moved out of the locking groove 1212. During installation, by rotating the handle 133 in the reverse direction, the locking tongue 131 can be locked into the locking groove 1212.

[0142] In addition, two limiting members 1124 are further provided on the first rear connecting ring 1121. As Figure 7 shown, the two limiting members 1124 are located at both ends of the handle avoidance hole 1113, and two convex blocks 134 are further provided at the inner end of the handle 133. The two convex blocks 134 are located inside the first rear connecting ring 1121 and are blocked by the two limiting members 1124 to prevent the handle 133 from detaching from the first rear connecting ring 1121.

[0143] In other embodiments, an elastic member can also be provided between the rotating member 132 and the inner wall of the first rear connecting ring 1121. The elastic member can pull the locking tongue 131 of the rotating member 132 to move towards the locking groove 1212 to prevent the locking tongue 131 from automatically detaching from the locking groove 1212. Of course, in other embodiments, the locking tongue 131 and the locking groove 1212 are in interference fit, and the locking tongue 131 can also be locked tightly.

[0144] It should be understood that in other embodiments, the first housing 11 and the second housing 12 can also be connected by snap connection, magnetic attraction connection, or bolt connection. The present invention does not limit the specific connection method between the first housing 11 and the second housing 12.

[0145] The kit 2 is installed in the first housing 11 and is provided with a plurality of reagent chambers 21 for containing reagents. As Figures 10 - 11 shown, the kit 2 is in the shape of a flat plate and is provided with a plurality of reagent chambers 21 and a plurality of flow channel holes 22. The plurality of reagent chambers 21 extend in the vertical direction and are arranged in a first direction, which is the width direction of the urine analyzer 100. The kit 2 is in the shape of a plate and is stacked with the flow channel plate 3. The outer periphery of the kit 2 is basically fitted to the inner wall of the first housing 11. The plurality of reagent chambers 21 basically fill the entire kit 2, can contain more reagents, and do not occupy too much space.

[0146] As Figure 6 、 Figure 10 shown, both the first front connection ring 1111 and the first rear connection ring 1121 of the first housing 11 are annular, that is, the inner side wall of the first housing 11 is an arc surface, the bottom end of the kit 2 also presents an arc shape, and the bottom ends of the plurality of reagent chambers 21 are arranged around a horizontal axis and are basically on the same circumference. The bottom ends of the plurality of reagent chambers 21 are close to the bottom end of the kit 2 to increase the utilization rate of the reagent chambers 21.

[0147] As Figure 10 shown, the bottom wall of the reagent chamber 21 includes an inclined surface 23 and a vertical surface 24. The vertical surface 24 extends in the vertical direction, and the inclined surface 23 is an inclined surface that gradually decreases from the rear to the front. The bottom end of the inclined surface 23 is connected to the top surface of the vertical surface 24.

[0148] The top end and the front side of the reagent chamber 21 are open. Reagents can be put in from the top end, and then a seal is set at the top end of the reagent chamber 21, or an oil seal can also be used. A sealing plate (not shown in the figure) is also installed at the front end of the kit 2. The sealing plate is stacked on the front side of the kit 2 and can seal the reagent chamber 21. Of course, when processing is convenient, the sealing plate can also not be set, and the front side of the sealing chamber is set in a sealed shape.

[0149] As Figure 10 and Figure 11 shown, the plurality of flow channel holes 22 are also arranged at intervals around the horizontal axis and are recessed from the rear side of the kit 2 towards the front end. The plurality of flow channel holes 22 are recessed to the vertical surface 24 and communicate with the plurality of reagent chambers 21. The inclined surface 23 is provided to facilitate the slow inflow of the reagent to the bottom end and flow into the flow channel plate 3 from the flow channel holes 22.

[0150] As Figure 10 and Figure 11 shown, a plurality of sealing grooves 25 are further provided on the rear side of the kit 2. The plurality of sealing grooves 25 are formed by recessing from the rear side of the kit 2, and the plurality of flow channel holes 22 are formed by recessing from the inner wall of the plurality of sealing grooves 25 away from the second housing 12 to the vertical surface 24. The sealing grooves 25 can also be set in a conical shape, that is, the sealing grooves 25 gradually decrease from the rear to the front and the external opening is larger.

[0151] As Figure 7 、 Figure 12 shown, the microfluidic chip includes a flow channel plate 3 and a cover plate 7 stacked on the front side of the flow channel plate 3. Among them, the cover plate 7 is located on the rear side of the reagent kit 2. The cover plate 7 is in the shape of a thin plate and is stacked on the rear side of the reagent kit 2 and the front side of the flow channel plate 3. A plurality of conical insertion posts 71 are provided on the front side of the cover plate 7. The plurality of insertion posts 71 are respectively located in a plurality of sealing grooves 25, and a plurality of sealing rings are sleeved outside the plurality of insertion posts 71, so that the plurality of insertion posts 71 and the plurality of sealing grooves 25 are hermetically connected.

[0152] As Figure 7 、 Figure 12 shown, a plurality of through holes 72 are further provided on the rear side of the cover plate 7. The plurality of through holes 72 extend to the front ends of the plurality of insertion posts and are respectively communicated with a plurality of flow channel holes 22. The reagent in the reagent chamber 21 can flow into the flow channel plate 3 through the flow channel holes 22 and the through holes 72 of the insertion posts 71.

[0153] The cover plate 7 and the reagent kit 2 are snap-connected or bonded, or connected by a thermoplastic method. The present invention does not limit the specific connection method between the cover plate 7 and the reagent kit 2.

[0154] In Figures 11 - 13 the illustrated embodiment, a card slot 26 is provided at the bottom end of the reagent kit 2, and a protruding buckle 73 is provided at the bottom end of the cover plate 7. The buckle 73 can be snapped into the card slot 26 of the reagent kit 2, so that the reagent kit 2 and the cover plate 7 can be quickly assembled.

[0155] The flow channel plate 3 is stacked on the rear side of the cover plate 7. The flow channel plate 3, the cover plate 7 and the reagent kit 2 are fixedly connected to the first front cover plate 1112 or the first rear cover plate 1122 of the first housing 11 by the same bolt. In Figure 4 and Figure 7 the illustrated embodiment, two mounting posts 14 are respectively provided on the inner walls of the first front cover plate 1112 and the first rear cover plate 1122 of the first housing 11, and the mounting posts 14 of the first front cover plate 1112 and the first rear cover plate 1122 are abutted against each other and are both provided with threaded holes. The threaded hole of the mounting post 14 of the first rear cover plate 1122 extends to the rear side of the first rear cover plate 1122. The bolt can be screwed into the threaded hole of the mounting post 14 of the first front cover plate 1112 from the rear side of the first rear cover plate 1122, so as to fix the first rear cover plate 1122 and the first front cover plate 1112.

[0156] In addition, as Figure 7As shown, the kit 2 is provided with a countersunk hole 27, and the first rear cover plate 1122 is further provided with another mounting post 14. The threaded hole of the mounting post 14 is arranged opposite to the countersunk hole 27, and a flange is further provided at the inner end of the mounting post 14. A part of the flange can abut against the rear side of the flow channel plate 3. Screwing a bolt into the countersunk hole 27 from the rear side of the first rear cover plate 1122 can fix the kit 2, the cover plate 7, and the flow channel plate 3 together on the first rear cover plate 1122, and make the kit 2, the cover plate 7, and the flow channel plate 3 fit tightly.

[0157] The front side of the flow channel plate 3 is provided with a central hole 31, a plurality of circumferential holes 32, a common flow channel 33, a sample flow channel, a clear water flow channel, an air flow channel 36, a plurality of reagent flow channels 37, and a detection flow channel 38. As Figures 14 - 16 shown, the central hole 31 is located on the above-mentioned horizontal axis, and the central hole 31 is a through hole 72 penetrating through the front and rear of the flow channel plate 3. The plurality of circumferential holes 32 are arranged at intervals on a circle centered on the central hole 31, that is, the plurality of circumferential holes 32 are on the same circle.

[0158] The inner ends of the sample flow channel, the clear water flow channel, the air flow channel 36, the detection flow channel 38, and the plurality of reagent flow channels 37 respectively extend to the plurality of circumferential holes 32 and communicate with the plurality of circumferential holes 32, while the outer ends of the sample flow channel, the clear water flow channel, the air flow channel 36, the detection flow channel 38, and the plurality of reagent flow channels 37 are respectively dispersed away from the central hole 31 to other positions of the flow channel plate 3. Among them, the outer end of the detection flow channel 38 communicates with the detection cavity of the detection mechanism, facilitating the sample and the reagent to flow into the detection cavity from the detection flow channel 38, and the outer ends of the plurality of reagent flow channels 37 respectively extend to another circle and are aligned and communicated with the plurality of through holes 72 of the plurality of cover plates 7.

[0159] In some embodiments, one clear water flow channel and one sample flow channel are respectively provided. The outer end of the clear water flow channel is communicated with the clear water collection cavity 412 of the collection cavity through a pipeline, facilitating water to enter the clear water flow channel from the clear water collection cavity 412. The sample flow channel is communicated with the sample collection cavity 411 through a pipeline, facilitating the sample to enter the sample flow channel from the sample collection cavity 411.

[0160] In Figure 14 and 16 the shown embodiments, two clear water flow channels and two sample flow channels are respectively provided. The inner ends of the two clear water flow channels and the two sample flow channels are respectively communicated with different circumferential holes 32. The usage methods of the two clear water flow channels and the two sample flow channels will be described in detail below.

[0161] To facilitate the connection of the sample flow channel, the detection flow channel 38, the reagent flow channel 37, and the air flow channel 36 to the sample collection chamber 411, the detection chamber, and the reagent chamber 21, a first adapter 301 is further installed at the rear side of the flow channel plate 3. The first adapter 301 can be installed in the first housing 11 or in the second housing 12.

[0162] Specifically, as Figure 18 and Figure 19 shown, if the first adapter 301 is installed in the first housing 11, the first adapter 301 is snap-connected or fixedly connected by bolts, or welded, etc. to the rear side of the flow channel plate 3. The specific connection method between the first adapter 301 and the rear side of the flow channel plate 3 is not limited.

[0163] The first adapter 301 is used to introduce samples and clear water into the microfluidic chip, and also discharge the waste liquid after detection in the detection plate into the collector, and then from the collector to the toilet. Moreover, after the reagent is used up, the first adapter 301 and the pipeline are disassembled together, and all the components in the new first housing are directly replaced, reducing pollution and increasing the service life of the urine analyzer.

[0164] As Figure 18 、 Figure 26 、 Figure 27 shown, the first adapter 301 is provided with seven transfer pipes. The seven transfer pipes are used to communicate with the sample collection chamber 411, the clear water collection chamber 412, the sewage discharge channel 416 of the detector, or the external air through multiple pipelines. The transfer pipes are preferably arranged at the top of the first adapter 301, which is convenient for samples or water to flow from the sample collection chamber 411 or the clear water collection chamber 412 into the flow channel plate 3, and is also convenient for the liquid in the detection chamber to flow into the sewage discharge channel 416 of the collector through the connecting pipe and the pipeline.

[0165] As Figure 18 、 Figure 26 、 Figure 27 shown, among the seven transfer pipes, two of the transfer pipes are connected to the sample collection chamber 411 of the collector, and this transfer pipe is defined as the sample transfer pipe 3011. Another two transfer pipes are connected to the clear water collection chamber 412 of the collector, and these two transfer pipes are defined as the clear water transfer pipes 3012. Another transfer pipe is connected to the air flow channel 36 of the flow channel plate 3, and is defined as the air transfer pipe 3013. Another transfer pipe is connected to the sewage discharge channel 416 of the collector, and is defined as the sewage discharge transfer pipe 3014. The last transfer pipe is connected to the drive pipeline, and is defined as the drive transfer pipe 3015.

[0166] As Figure 18 shown, seven first slots 3016 are provided on the front side of the first adapter 301. Seven channels are provided in the first adapter 301. The multiple channels extend forward and communicate with the seven transfer pipes. The bottom ends of the seven channels communicate with the multiple first slots 3016.

[0167] As Figure 14 , Figure 17 shown, nine first adapter posts 3017 are further provided on the rear side of the flow channel plate 3. Each of the nine first adapter posts 3017 is provided with a first adapter hole, and the nine first adapter holes respectively extend into the flow channel plate 3 and communicate with the clear water flow channel, the detection flow channel 38, the sample flow channel or the air flow channel 36 of the flow channel plate 3. Seven of the nine first adapter posts 3017 are respectively inserted into seven first slots 3016 of the first adapter member, and the other two need to be inserted into the inlet and outlet of the detection plate. Among the seven first adapter posts, the first adapter holes of two of the first adapter posts 3017 communicate with two sample flow channels of the flow channel plate 3, and the first adapter holes of the two first adapter posts 3017 also communicate with two sample adapter pipes 3011. The first adapter holes of the other two first adapter posts 3017 communicate with two clear water flow channels and also communicate with two clear water adapter pipes 3012.

[0168] As Figure 14 , Figure 17 , Figure 18 shown, the first adapter hole of one of the first adapter posts 3017 communicates with the air flow channel 36 and the air adapter pipe 3013. The first adapter hole of another first adapter post 3017 communicates with the driving pipe and the driving adapter pipe 3015. There are also three first adapter holes of the first adapter posts 3017. One of them is used to communicate with the sewage adapter pipe 3014, and the other two are used to communicate with the detection chambers respectively, which will be described in detail below.

[0169] In short, the seven first adapter posts 3017 are respectively inserted into the seven first slots 3016 of the first adapter member, so that the outer ends of the sample flow channels of the flow channel plate 3 communicate with the sample adapter pipes 3011, the outer ends of the clear water flow channels communicate with the clear water adapter pipes 3012, the outer ends of the air flow channels 36 communicate with the air adapter pipes 3013, and the outer ends of the detection flow channels 38 communicate with the sewage adapter pipes 3014.

[0170] In another embodiment, the first adapter member 301 is installed in the second housing 12 or can also be installed in the installation groove. Since the second housing 12 and the first housing 11 are detachably connected, regardless of whether the first adapter member 301 is connected inside or outside the second housing 12, a plurality of first slots 3016 of the first adapter member 301 need to be exposed in the installation groove 1211 of the second housing 12.

[0171] As Figure 17As shown, a plurality of first adapter posts 3017 are also provided on the rear side of the runner plate 3, and the first rear cover plate 1122 of the first housing 11 needs to be provided with avoidance holes for avoiding the plurality of first adapter posts 3017, so that the first adapter posts 3017 can be inserted into the first slots 3016 of the first adapter 301 as the first housing 11 and the second housing 12 are assembled.

[0172] As Figure 6 , Figure 17 , Figure 18 As shown, when the first housing 11 and the second housing 12 are assembled, when the locking tongue 131 of the locking member 13 penetrates into the locking groove 1212, the plurality of first adapter posts 3017 can be simultaneously pressed into the plurality of first slots 3016 respectively.

[0173] Of course, in order to increase the sealing performance between the first adapter 301 and the runner plate 3, a sealing ring sleeved outside the first adapter post 3017 needs to be provided in the first slot 3016.

[0174] As Figure 18 , Figure 19 As shown, the detection plate 5 can be installed in the first housing 11 and fixedly connected or clamped to the first adapter 301, or fixedly connected to the rear side of the runner plate 3. Of course, in other embodiments, the detection plate 5 can also be arranged in the second housing 12 and configured to be detachably connected to the first adapter 301.

[0175] Figure 14 , 19 As shown, if it is arranged in the first housing 11, the detection plate 5 can be directly fixedly connected to the rear side of the runner plate 3. One end of the detection cavity is communicated with the detection runner 38, and the other end is communicated with the sewage transfer pipe 3014 of the first adapter 301. The sewage transfer pipe 3014 is communicated with the sewage discharge channel 416 of the collector through a pipeline. The liquid in the detection runner 38 flows into the detection cavity for detection, and after the detection is completed, the liquid in the detection cavity can flow into the sewage discharge channel 416 from the sewage transfer pipe 3014 and be discharged into the toilet from the sewage discharge channel 416.

[0176] Specifically, as Figure 5 , Figure 19 , Figure 21 As shown, the detection plate 5 is a plate-shaped one extending forward and backward along the urine detector 100. The detection cavity is generally U-shaped and has a liquid inlet 51 and a liquid outlet 52, and the liquid inlet 51 and the liquid outlet 52 are respectively located at the front end of the detection plate 5. As Figure 17Among them, there are three first adapter posts 3017 on the rear side of the flow channel plate 3. Two of the first adapter posts 3017 are respectively inserted into the liquid inlet 51 and the liquid outlet 52. The first adapter post 3017 inserted into the liquid inlet 51 connects the detection flow channel 38 of the flow channel plate 3 and the liquid inlet 51. The samples and liquids in the detection flow channel 38 can flow into the detection cavity from the liquid inlet 51 in sequence for detection. That is to say, one end of the detection cavity is connected to the detection flow channel, and the other end is connected to the sewage discharge pipe.

[0177] As Figure 14 , Figure 17 , Figure 18 shown, the flow channel plate 3 is also provided with a sewage discharge flow channel 302. Both ends of the sewage discharge flow channel 302 are respectively connected to the other two first adapter posts 3017 on the rear side of the flow channel plate 3. One of the first adapter posts 3017 of the two first adapter posts 3017 is inserted into the liquid outlet 52 of the detection cavity, and the first adapter hole of the first adapter post 3017 is connected to the liquid outlet 52. The other first adapter post 3017 is inserted into the first slot 3016 at the front end of the first adapter 301 and is connected to the sewage discharge adapter pipe 3014 located at the top of the first adapter 301.

[0178] That is to say, the mixed liquid of the samples and reagents in the detection flow channel 38 flows into the detection cavity from the first adapter hole of one of the first adapter posts 3017 and the liquid inlet 51 of the detection cavity. After the detection is completed, the mixed liquid then flows from the liquid outlet 52 into the sewage discharge flow channel 302 of the flow channel plate 3, and then flows from the sewage discharge flow channel 302 into the sewage discharge adapter pipe 3014, and flows into the sewage discharge channel 416 of the collector from the sewage discharge adapter pipe 3014 and the pipeline, and then flows into the toilet from the sewage discharge channel 416.

[0179] The function of the sewage discharge flow channel 302 is equivalent to a flow channel for transfer. One end is connected to the liquid outlet 52 of the detection cavity, and the other end is connected to the sewage discharge adapter pipe 3014. The mixed liquid in the detection cavity passes through the sewage discharge flow channel 302 and then flows into the sewage discharge adapter pipe 3014 from the sewage discharge flow channel 302. This design can reduce the volume of the first adapter 301 and make full use of the internal space of the flow channel plate 3 and the first adapter 301.

[0180] If the detection plate 5 is installed in the first housing 11, when the reagents in the first housing 11 are exhausted, it can be disassembled along with the first housing 11. When replacing the new detection device, a new detection plate 5 is also installed inside it.

[0181] The detector of the present invention includes a light source device and a photosensitive sensor, which are respectively arranged at corresponding positions of the detection plate 5. The detection plate 5 is made of a transparent material. The light source device is an LED light, which is used to irradiate the mixed liquid in the detection chamber, and the photosensitive sensor is used to sense the light after the light source device irradiates the mixed liquid to detect the sample components. However, the installation of the detector is relatively complex. Therefore, for the convenience of customers' assembly, the detector needs to be installed in the second housing 12, that is, the detector and the detection plate 5 are assembled separately. And the detector needs to be close to the detection plate 5 to detect the mixed liquid in the detection chamber. Therefore, the rear end of the detection plate 5 needs to extend into the second housing 12.

[0182] Specifically, as Figure 20 shown, avoidance holes need to be provided on the inner walls of the first rear cover plate 1122 of the first housing 11 and the installation groove 1211 of the second housing 12 respectively. This avoidance hole is the detection plate avoidance hole 15. The front end of the detection plate 5 is connected to the flow channel plate 3 and the first adapter 301, and the rear end extends into the second housing 12 from the two detection plate avoidance holes 15 of the first housing 11 and the second housing 12. The detector is installed at the top or bottom of the detection plate avoidance hole 15 of the second housing 12, and can detect the liquid in the detection chamber.

[0183] In another embodiment, the detection plate 5 can also be directly installed in the second housing 12. The front end of the detection plate 5 extends to the inner wall of the installation groove 1211. Among the three first adapter posts 3017 at the rear end of the flow channel plate 3, the first adapter holes of two of the first adapter posts 3017 are respectively communicated with both ends of the sewage flow channel 302. One of the first adapter holes of one of the two first adapter posts 3017 is communicated with the sewage adapter pipe 3014, and the other is communicated with the flow outlet 52 of the detection chamber.

[0184] Among the three first adapter posts 3017, the first adapter hole of the other first adapter post 3017 is communicated with the flow inlet 51 of the detection chamber.

[0185] The two first adapter posts 3017 communicated with the flow inlet 51 and the flow outlet 52 of the detection chamber need to extend to the rear side of the first rear cover plate 1122 of the first housing 11. When the first housing 11 and the second housing 12 are assembled, the rear ends of the two first adapters 301 can be inserted into the two flow inlets 51 and the flow outlet 52 at the front end of the detection plate 5, and quick disassembly and assembly can also be achieved.

[0186] It should be understood that a sealing connection is required between the multiple adapter pipes and the multiple first adapter posts 3017 or between the first adapter post and the flow outlet 52 and the flow inlet 51. The sealing method can be selected as an O-ring or other methods.

[0187] The common flow channel 33 is a curved flow channel, and its inner end extends to the central hole 31 and communicates with the central hole 31. The outer end bends around the central hole 31 within the circle formed by the multiple circumferential holes 32 and then bends and extends to the outside of the flow channel plate 3. The common flow channel 33 and the multiple circumferential holes 32 are arranged in a staggered manner and do not communicate directly with each other.

[0188] In one embodiment, the outer end of the common flow channel 33 is used to communicate with the drive pipe 94, and the drive pipe 94 is located within the second housing and is connected to a pump. The pump can extract the air within the drive pipe 94 and the common flow channel 33. Of course, in some embodiments, two pumps can be arranged in series through a pipe, and one of the pumps is connected to the drive pipe 94.

[0189] In Figure 14 In the illustrated embodiment, at least one bend is provided in the middle part of the common flow channel 33. On the one hand, it increases the volume of the common flow channel 33, and on the other hand, it prevents the reagent or sample within the common flow channel 33 from flowing back into the drive pipe.

[0190] The common flow channel 33 needs to communicate with the drive pipe 94, and the pump is connected to the drive pipe. After the pump is started, the air within the common flow channel 33 can be emptied to form a negative pressure.

[0191] The pump and the drive pipe are respectively located within the second housing 12. Therefore, in order to achieve quick disassembly and assembly of the drive pipe and the common flow channel 33, a second adapter 306 also needs to be installed. The second adapter 306 will be introduced below.

[0192] As a preferred solution, in order to more accurately and quantitatively extract the reagent and sample, two pumps can be used to communicate with the common flow channel through two drive pipes respectively. One is a peristaltic pump 91, and the other is a plunger pump 92. The two pumps are respectively installed within the second housing 12 and are respectively connected to the two drive pipes. The two drive pipes are respectively defined as the first drive pipe and the second drive pipe.

[0193] The second drive pipe is connected to the plunger pump, and the first drive pipe is connected to the peristaltic pump 91. The first drive pipe includes two sections. The two ends of the two sections are respectively connected to the two ends of the hose of the peristaltic pump, and the other two sections are respectively connected to the two peristaltic pump adapter posts 3041 described below.

[0194] There is also a drive flow channel 303 on the front side of the flow channel plate 3. The drive flow channel 303 extends in the vertical direction and its top end communicates with the first adapter hole of one of the first adapter posts 3017. The first adapter hole communicates with the drive adapter pipe 3015.

[0195] There are also three second adapter posts on the rear side of the flow channel plate 3. The three second adapter posts are respectively provided with second adapter holes. Among the three second adapter posts, two of them are peristaltic pump adapter posts 3041, and the other one is a plunger pump adapter post 3042.

[0196] As Figure 14 、 Figure 17 shown, the second transfer hole of one of the two peristaltic pump transfer posts 3041 communicates with the bottom end of the drive channel 303, and the second transfer hole of the other peristaltic pump transfer post 3041 communicates with the common channel 33.

[0197] The plunger pump transfer post 3042 is located between the two peristaltic pump transfer posts 3041 and its second transfer hole also communicates with the common channel 33.

[0198] Figure 17 、 Figure 18 shown, the second adapter 306 is connected to the inner wall of the installation groove 1211 of the second housing 12 and is provided with three second slots 3061. Among the three second slots 3061, two of the second slots 3061 respectively accommodate the two peristaltic pump transfer posts 3041. That is, the common channel 33 communicates with one end of one section of the first drive pipe through one peristaltic pump transfer post 3041, and one end of the other section of the first drive pipe communicates with the bottom end of the drive channel 303 through the other peristaltic pump transfer post 3041. The top end of the drive channel 303 is connected to the drive adapter 3015 through the first connection post, and the drive adapter 3015 can also be connected to the collector. That is to say, one end of the two sections of the first drive pipe is respectively connected to both ends of the hose of the peristaltic pump, and the other end is respectively connected to the common channel and the drive adapter 3015. After the peristaltic pump is started, the fluid in the common channel can be pumped from the first drive pipe and the drive adapter to the collector and discharged from the collector into the toilet.

[0199] Among the three second slots 3061, another second slot 3061 communicates with one end of the second drive pipe, and the second slot 3061 accommodates the plunger pump transfer post 3042.

[0200] The peristaltic pump 91 is used to drive the air in the common channel 33 to be discharged, or drive the sample and water in the sample collection cavity to the sample channel and the clean water channel. That is to say, a larger air flow is required. Therefore, the drive channel 303 is provided on the flow channel plate 3, and the drive adapter 3015 is provided on the first adapter 301. If it is bent, a larger air flow can be provided. The plunger pump 92 only needs to quantitatively extract the sample and reagent in the sample channel and the reagent channel 37 to the common channel, and the required flow is smaller. Therefore, one end of the second drive pipe communicates with the common channel 33, and the other end is arranged near the plunger pump 92.

[0201] As Figure 5As shown, the detection flow channel 38 is in communication with the detection cavity, and a mixing cavity 39 is further provided on the path of the detection flow channel 38. The mixing cavity 39 is in communication with the detection flow channel 38 and the width of the mixing cavity 39 is greater than the diameter dimension of the detection flow channel 38. When the sample and the reagent flow in the detection flow channel 38, they pass through the mixing cavity 39. Due to the relatively large width of the mixing cavity 39, the sample and the reagent will accelerate when flowing from the detection flow channel 38 into the mixing cavity 39, and thus are mixed in the mixing cavity 39.

[0202] As a preferred solution, the mixing cavity 39 includes a mixing bend 392 and at least one mixing chamber 391 that are in communication with each other. The mixing bend 392 is an S-shaped curved flow channel, and the mixing chamber 391 is in communication with the mixing bend 392, and the width dimension of the mixing cavity 39 is greater than the diameter dimensions of the mixing bend 392 and the detection flow channel 38.

[0203] In Figures 14 - 16 In the illustrated embodiment, the mixing cavity 39 includes three mixing bends 392 and three mixing chambers 391. The three mixing chambers 391 and the three mixing bends 392 are alternately arranged and in communication with each other, and the inlet of the mixing cavity 39 is at the bottom end and the outlet is at the top end. That is to say, the three mixing bends 392 and the mixing cavity 39 extend upward in a curved shape.

[0204] The mixing bend 392 includes at least two horizontal flow channels and at least one turning flow channel 394, and any one of the turning flow channels 394 is located at both ends of the two horizontal flow channels;

[0205] The mixing bend 392 is an S-shaped bend and includes at least two horizontal flow channels and at least one turning flow channel 394. The horizontal flow channel is a flow channel extending in the horizontal direction, and the turning flow channel 394 is located between any two horizontal flow channels, that is, at the corner of the mixing bend 392.

[0206] As Figure 16 As shown, the turning flow channel 394 includes a curved inner arc 395 and an outer arc 396. Both the inner arc 395 and the outer arc 396 are arc-shaped and the inner diameter of the inner arc 395 is smaller than the inner diameter of the outer arc 396.

[0207] The mixing cavity 39 of the present invention uses an S-shaped mixing bend 392 in cooperation with the mixing cavity 39, and an outer diameter enlargement treatment is performed at the turning corner of the mixing bend 392. By using the variable-diameter bend here, the flow velocity at the outer arc 396 is greater than the flow velocity at the inner arc 395, forming a local Dean flow effect, and improving the mixing effect of the mixed liquid of the sample and the reagent in the flow channel.

[0208] As Figure 15As shown, the vertical section of the mixing chamber 391 is approximately circular, and the two side walls of the mixing chamber 391 are also arc-shaped surfaces. The two arc-shaped surfaces are the first arc-shaped surface 397 and the second arc-shaped surface 398 opposite to the first arc-shaped surface 397 respectively. Both the first arc-shaped surface 397 and the second arc-shaped surface 398 are arc-shaped surfaces protruding towards the outside.

[0209] As a preferred solution, as Figure 15 shown, the first arc-shaped surface 397 and the second arc-shaped surface 398 are circular arc surfaces with the same diameter and the same arc length, and the tangents at both ends of the first arc-shaped surface 397 and the second arc-shaped surface 398 are parallel to each other. In the embodiment shown in the figure, the arc length of the first arc-shaped surface 397 is equal to 1 / 4 of the circumference of the circle, and the tangents at both ends are perpendicular to each other, and one of the tangents extends in the vertical direction and the other extends in the horizontal direction.

[0210] Since the entire mixing cavity 39 extends in a bent manner in the vertical direction, as Figure 16 shown, each mixing chamber 391 is located between two mixing bends 392. Each mixing cavity 39 needs to be connected to the horizontal flow channels of the two mixing bends 392. The two horizontal flow channels are symmetrically arranged in a mirror image. One of them is located at the top end of the mixing chamber 391, and the other is located at the bottom end of the mixing chamber 391.

[0211] Among the two horizontal flow channels connected to the mixing chamber 391, one of the horizontal flow channels is defined as the liquid inlet horizontal flow channel 3931, and the other horizontal flow channel is defined as the liquid outlet horizontal flow channel 3932. The liquid inlet horizontal flow channel 3931 is connected to the top end of the mixing chamber 391, and the liquid outlet horizontal flow channel 3932 is connected to the bottom end of the mixing chamber 391. The sample or reagent flows into the mixing chamber 391 from the liquid inlet horizontal flow channel 3931 and then flows out from the liquid outlet horizontal flow channel 3932. That is to say, the liquid inlet horizontal flow channel 3931 is located upstream of the liquid outlet horizontal flow channel 3932. The sample and reagent flow from the common flow channel 33 into the detection flow channel 38. After passing through, for example, the mixing cavity 39, they enter the mixing chamber 391 from the liquid inlet horizontal flow channel 3931 of one mixing bend and then flow into the horizontal flow channel of another mixing bend.

[0212] As Figure 15 shown, the mixing chamber 391 has a sample inlet 3911 and a sample outlet 3912. Among them, the sample inlet 3911 is connected to the liquid inlet horizontal flow channel of one of the mixing bends, and the sample outlet 3912 is connected to the liquid outlet horizontal flow channel 3932 of another mixing bend. The sample and reagent can flow into the mixing chamber from the liquid inlet horizontal flow channel of one of the mixing bends and the sample inlet 3911, and then flow into another mixing bend from the sample outlet 3912 and the liquid outlet horizontal flow channel, and continuously flow in several mixing chambers and several mixing bends.

[0213] Taking the connection line between the liquid inlet horizontal flow channel 3931 and the liquid outlet horizontal flow channel 3932 as the dividing line, asFigure 15 The dotted line shown is a dividing line. This dividing line can divide the mixing chamber 391 into two parts. Among them, the area formed by this dividing line and the first arc surface 397 located below is the slow zone 3934, and the area between the dividing line and the second arc surface 398 is the fast zone 3933. There is a certain speed difference between the flow entering the fast zone 3933 and the slow zone 3934 of the mixing chamber 391 from the inlet horizontal flow channel 3931. The mixed liquid of the sample and the reagent forms a vortex around the center point in the circular mixing chamber 391, increasing the contact area between the liquids and improving the mixing effect.

[0214] Due to the narrowing of the outlet horizontal flow channel 3932, when the mixed liquid of the sample and the reagent flows out from the outlet horizontal flow channel 3932, the speed suddenly increases, and the mixed liquid of the sample and the reagent is relatively squeezed, further increasing the mixing intensity of the mixed liquid of the sample and the reagent. Through the series connection of the mixing bends 392 with multiple diameter changes and the circular mixing chamber 391, the mixing intensity is gradually increased until the detection chamber, and the sample and the reagent are basically in a completely mixed state.

[0215] This mixing chamber 39 of the present invention is commonly used in the technical fields of microfluidic chip such as biology and chemistry. When a sample or a reagent or a mixture of a sample and a reagent is required, by using this structure, the mixing efficiency can be greatly improved, and at the same time, some residue and bubble problems can be avoided.

[0216] In the mixing chamber 39, the inlet horizontal flow channel 3931 communicating with each mixing chamber 391 is set relatively higher than the outlet horizontal flow channel 3932. In a special application scenario, such as when it needs to be used vertically, when the liquid flows from bottom to top, the influence of gravity does not need to be considered, so that there will be no residue problem in the mixing chamber 391.

[0217] When the sample or the reagent flows in a relatively rough flow channel, bubbles are easily generated, which will affect the mixing effect and even be brought into the detection chamber, causing analysis errors. The multiple mixing chambers 39 of the core of the present application are connected in series with the mixing bends 392, and smooth fillet transitions are made at the flow channel corners of each mixing bend 392, which can avoid and eliminate bubbles in the mixing chamber 391 to a certain extent.

[0218] The inlet of the mixing chamber 39 is located below the outlet. The mixing chamber 39 is located above the common flow channel 33. The inlet of the mixing chamber 39 is connected to the common flow channel 33, and the outlet is connected to the detection chamber. After the sample and the reagent in the common flow channel 33 flow into the mixing chamber 39 from the bottom inlet of the mixing chamber 39, they then flow into the detection chamber from the outlet.

[0219] Such as Figure 14 、 Figure 22As shown, the rotor 6 is rotatably installed inside the first housing 11 and is located on the rear side of the flow channel plate 3. A transfer channel is provided inside the rotor 6. The inner end 61 and the outer end of this transfer channel open towards the front side of the rotor 6. The transfer channel is generally U-shaped. The inner end 61 of the transfer channel is aligned with the central hole 31, and the inner end is recessed from the front side of the rotor 6 into the interior of the rotor 6. The outer end 62 of the transfer channel also opens towards the front side of the rotor 6, and the distance from the outer end 62 to the inner end 61 is the same as the distance between the central hole 31 and the plurality of circumferential holes 32.

[0220] As Figure 14 , Figure 22 shown, the inner end 61 of the transfer channel is aligned and communicated with the central hole 31, and the outer end 62 rotates with the rotor 6 and can be aligned and communicated with any one of the circumferential holes 32 as the rotor 6 rotates.

[0221] When a sample needs to be extracted, the rotor 6 rotates so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 that is communicated with the inner end of the sample flow channel. At this time, both ends of the transfer channel are respectively communicated with the sample flow channel and the common flow channel 33. The peristaltic pump 91 can extract the air in the common flow channel 33, the transfer channel, the sample flow channel, and the external sample transfer pipe or the pipe communicated with the transfer pipe, forming a negative pressure, and extracting the sample in the sample collection cavity 411 to the common flow channel 33.

[0222] When a reagent needs to be extracted, perform the same operation. Rotate the rotor 6 so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 that is communicated with the reagent flow channel 37, so that the common flow channel 33 is communicated with the reagent channel. The peristaltic pump 91 discharges the air in the common flow channel 33 and the reagent channel, forming a negative pressure, and extracting the reagent in the reagent cavity 21 to the common flow channel 33.

[0223] When extracting the clear water in the clear water collection cavity 412, the same operation is performed, which will not be elaborated here.

[0224] After the sample and the reagent are drawn into the common flow channel 33, the rotor 6 continues to rotate so that the outer end 62 of the transfer channel faces the circumferential hole 32 that is communicated with the inner end of the detection flow channel 38. The peristaltic pump 91 drives the sample and the reagent in the common flow channel 33 to flow from the common flow channel 33 into the detection flow channel 38, and then flows from the detection flow channel 38 into the detection cavity.

[0225] In the embodiment where the mixing cavity 39 is provided, the peristaltic pump 91 can push the sample and the reagent from the detection flow into the mixing cavity 39, and push the sample and the reagent from the bottom inlet of the mixing cavity 39 to the top outlet. For the mixing effect, the peristaltic pump 91 can also reverse the flow of the sample and the reagent in the mixing chamber 391 and the mixing bend 392 repeatedly. After the sample and the reagent pass through the mixing chamber 391 and the plurality of mixing bends 392, they are repeatedly mixed to form a mixed liquid. Until the mixing effect is achieved, finally, the mixed liquid is flowed into the detection cavity from the inlet 51 of the detection cavity

[0226] According to the above description, the runner plate 3 is also provided with a sewage discharge runner 302. The two ends of the sewage discharge runner 302 are respectively communicated with the first transfer holes of the other two first transfer posts 3017 at the rear side of the runner plate 3. One of the two first transfer posts 3017 is inserted into the outflow port 52 of the detection cavity, and the first transfer hole of the first transfer post 3017 is communicated with the outflow hole. The other first transfer post 3017 is inserted into the first slot 3016 at the front end of the first transfer member 301 and is communicated with the sewage discharge transfer pipe 3014 located at the top end of the first transfer member 301.

[0227] After the detection is completed, the pump drives air into the detection runner 38 and the detection cavity again, and the mixed liquid flows from the outflow port 52 of the detection cavity into the sewage discharge runner 302, then flows from the sewage discharge runner 302 into the sewage discharge transfer pipe 3014, and flows from the sewage discharge transfer pipe 3014 and the pipeline into the sewage discharge channel 416 of the collector, and then flows into the toilet due to the sewage discharge channel 416.

[0228] The rotor 6 is rotatably connected to the rear side of the runner plate 3. In a specific embodiment, a connecting member 85 is further provided on the rear side surface of the runner plate 3. The connecting member 85 is annularly formed by extending around the outside of a plurality of circumferential holes 32 and is located radially outside the rotor 6.

[0229] A protective cover 81 is also sleeved outside the rotor 6. As Figure 22 and 23 shown, the protective cover 81 covers the connecting member 85 and is also clamped with the connecting member 85, and the rotor 6 rotates in the protective cover 81.

[0230] In addition, as Figure 22 , Figure 23 shown, in order to drive the rotor 6 to abut against the rear side surface of the runner plate 3 and prevent liquid from overflowing from the circumferential holes 32, a compression spring 82 is further provided inside the protective cover 81, and a convex ring 83 is provided on the rear side of the rotor 6. The compression spring 82 is sleeved outside the convex ring 83 and the front and rear ends abut against the rear side of the rotor 6 and the rear wall of the protective cover 81, so that the rotor 6 and the runner plate 3 are closely fitted. Of course, the compression spring 82 can also be replaced with other biasing members, such as magnets attracting each other are respectively provided on the rotor 6 and the runner plate 3.

[0231] The driving member 93 is located inside the second housing 12 and is detachably connected to the rotor 6. As Figure 24 shown, the driving member 93 can be a motor. Of course, other driving methods can also be selected. The rotating shaft of the motor extends into the installation groove 1211 of the second housing 12. After the second housing 12 and the first housing 11 are assembled, the rotating shaft of the motor and the rotor 6 can be automatically assembled.

[0232] Specifically, the first rear cover plate 1122 of the first housing 11 is provided with an avoidance hole for avoiding the protection cover 81, and the inner wall of the installation groove 1211 of the second housing 12 is also provided with an avoidance hole for avoiding the motor rotating shaft. The rear side of the protection cover 81 is located in the avoidance hole of the first rear cover plate 1122 and is also provided with a perforation, and the rotating shaft of the driving member 93 extends from the avoidance hole on the inner wall of the installation groove 1211 into the protection cover 81. In addition, a recessed spline groove 84 is provided on the rear side of the convex ring 83, as Figure 23 and 24 shown, and a spline 931 located in the spline groove 84 is provided at the front end of the motor rotating shaft. When the first housing 11 and the second housing 12 are assembled, the spline 931 of the rotating shaft is inserted into the spline groove 84 to complete the assembly.

[0233] The collector is located outside the first housing 11 and the second housing 12, and the collector is connected to the adapter pipe of the first adapter 301 through a plurality of pipes.

[0234] In Figures 25 - 27 the illustrated embodiment, the collector includes a collection plate 41, an outer cover plate 43, an inner cover plate 42, and a clear water collection member. The collection plate 41 is disc-shaped and has an outer side and an inner side. The outer side is the side away from the toilet, and the inner side is the side close to the toilet. A sample collection cavity 411 is provided on the outer side of the collection plate 41, and a clear water collection cavity 412 is provided on the rear side.

[0235] The sample collection cavity 411 is located at the top of the collection plate 41 and the width gradually increases from the bottom to the top and opens towards the top end of the collection plate 41. This opening is used to collect samples. The clear water collection cavity 412 is located at the bottom of the collection plate 41 and is arranged offset from the sample collection cavity 411.

[0236] The top end of the collection plate 41 is also provided with a water inlet channel 413, a water outlet channel 414, and a sample outlet channel 415. The water inlet channel 413 and the water outlet channel 414 are respectively communicated with the clear water collection cavity 412. Both the water inlet channel 413 and the water outlet channel 414 are located at the rear side of the collection plate 41 and are recessed from the top end of the collection plate 41 into the clear water collection cavity 412.

[0237] The sample collection cavity 411 is located on the front side of the collection plate 41, which is a groove formed by recessing the front side of the collection plate 41. After the collection plate 41 and the outer cover plate 43 are connected and joined together, the sample collection cavity 411 is formed. The top end of the front cover plate is provided with a filtering portion 44. The filtering portion 44 is a grille spaced apart at the top end of the front cover plate, and a filter screen or the like can also be added to filter foreign matters.

[0238] The inner walls on both sides of the sample collection cavity 411 are arc surfaces protruding towards each other, so that the width of the sample collection cavity 411 gradually increases from the bottom end to the top end. In addition, the arc-shaped inner wall can increase the opening of the sample collection cavity 411 and also facilitate the sample to flow from the top end to the bottom end.

[0239] The inner wall of the sample collection chamber 411 is also provided with two recessed drainage grooves 4111. The two drainage grooves 4111 are respectively recessed downward from the top of the collection plate 41 and are spaced apart. A partition column 402 is formed between the two drainage grooves 4111. The partition column 402 is basically located at the middle position of the sample collection chamber 411, and the two drainage grooves 4111 are also basically the same in shape. The bottom walls of the two drainage grooves 4111 are also arc surfaces recessed downward.

[0240] The drainage grooves 4111 are convenient for receiving more samples, and also convenient for the samples to flow along the inner walls of the drainage grooves 4111, providing a larger flow channel arc surface, facilitating the samples to slowly flow into the bottom end of the sample collection chamber 411 and reducing the generation of bubbles.

[0241] It should be understood that if there is enough space in the sample collection chamber 411, multiple drainage grooves 4111 can also be provided. The multiple drainage grooves 4111 can be arranged at intervals along the width direction of the collector. The inner walls and bottom walls of the multiple drainage grooves 4111 are preferably smooth arc surfaces for sampling.

[0242] The bottom end of the sample collection chamber 411 is also provided with a sewage outlet 417. The sewage outlet 417 is open towards the bottom end of the collection chamber and the diameter of the sewage outlet 417 is very small. During the sample collection process, the sewage outlet 417 is always in an open state. Due to its small diameter, it will not affect the sample collection.

[0243] A liquid level sensor is also provided in the sample collection chamber 411. The liquid level sensor is located below the two drainage grooves 4111 and adjacent to the drainage grooves 4111, and is used to sense the liquid level of the sample collection.

[0244] In addition, the sample outlet channel 415 is formed by recessing the rear side of the collection plate 41, and the bottom end of the sample outlet channel 415 extends into the sample collection chamber 411 and is located above the sewage outlet 417, while the top end is located at the upper end of the collection plate 41. The top end of the sample outlet channel 415 is connected to the sample transfer pipe 3011 through a pipeline. The sample in the sample collection chamber 411 can flow into the sample flow channel through the sample outlet channel 415 and the sample transfer pipe 3011.

[0245] The clean water collection chamber 412 is formed by recessing the rear side of the collection plate 41. After the inner cover plate 42 is connected to the rear side of the collection plate 41, the inner cover plate 42 covers the clean water collection chamber 412 to form a closed cavity.

[0246] The clean water collection chamber 412 includes a first chamber 4121 and a second chamber 4122. The first chamber 4121 and the second chamber 4122 are located on both sides of the sample collection chamber 411 and are connected at the bottom. The first chamber 4121 and the second chamber 4122 are symmetrically arranged, and exhaust holes 418 are respectively provided at the top ends.

[0247] The water inlet channel 413 and the water outlet channel 414 are respectively formed by depressions on the rear side of the collection plate 41, and the bottom end of the sample outlet channel 415 communicates with the bottom end of the sample collection chamber 411.

[0248] The top end of the water inlet channel 413 is also connected to an external clean water collection component. This clean water collection component can be a pipe connected to a clean water tank or a water switch, or directly a pipe is provided and adhered to the inner wall of the toilet and above the collector for collecting clean water. The present invention does not limit the specific implementation manner of the clean water collection component.

[0249] The diameter of the water outlet channel 414 is much smaller than that of the water inlet channel 413, and the top end of the water outlet channel 414 can be connected to the clean water adapter tube 3012 through a pipe.

[0250] That is to say, the water collected by the clean water collection component flows into the clean water collection chamber 412 from the water inlet channel 413. This clean water collection chamber 412 is similar to a water storage tank, and the water in the clean water collection chamber 412 then enters the clean water flow channel of the flow channel plate 3 through the water outlet channel 414 and the clean water adapter tube 3012.

[0251] After the water of the clean water collection component enters the clean water collection chamber 412, bubbles will be generated. These bubbles will float to the water surface. The water outlet channel 414 is located at the bottom end of the clean water collection chamber 412, and the water outlet channel 414 is relatively thin, so the bubbles will not enter the water outlet channel 414. After flowing into the clean water adapter tube 3012 from the water outlet channel 414, there will be no bubbles in the clean water flowing into the clean water flow channel.

[0252] A liquid level sensor is also installed in the clean water collection chamber 412 for sensing the liquid level of the clean water.

[0253] A sewage discharge channel 416 is also provided on the rear side of the collection plate 41. The sewage discharge channel 416 extends to the top end of the collection plate 41 and is connected to a sewage discharge adapter tube 3014 through a pipe. This sewage discharge adapter tube 3014 is connected to the detection chamber, and the inner cover plate 42 is also provided with a liquid outlet 421 communicating with the sewage discharge channel 416. After the detection is completed, the mixed liquid in the detection chamber can flow into the sewage discharge channel 416 from the sewage discharge flow channel 302 of the flow channel plate 3 and the sewage discharge adapter tube 3014 in sequence, and then flow into the toilet from the sewage discharge channel 416 and the liquid outlet 421.

[0254] In Figures 28 - 30 In another embodiment described above, the collector also includes a collection plate 41, an outer cover plate 43, an inner cover plate 42 and a clean water collection component. Similarly, the collection plate 41 is also disc-shaped and is also provided with a clean water collection chamber 412 and a sample collection chamber 411. The top surface of the collection plate 41 is also provided with a water inlet channel 413, a water outlet channel 414 and a sample outlet channel 415.

[0255] In contrast, the sample collection chamber 411 and the clean water collection chamber 412 are formed by the splicing of the collection plate 41, the inner cover plate 42 and the outer cover plate 43. The sample collection chamber 411 and the clean water collection chamber 412 are through grooves provided on the collection plate 41. After the front cover plate and the rear cover plate are covered on the front and rear sides of the collection plate 41, the front and rear sides of the sample collection chamber 411 and the clean water collection chamber 412 are sealed to form the sample collection chamber 411 and the clean water collection chamber 412.

[0256] The volume of the clean water collection chamber 412 is larger than that of the sample collection chamber 411. The clean water collection chamber 412 and the sample collection chamber 411 are respectively on both sides of the collection plate 41, and there is an isolation part in the middle.

[0257] A sample collection groove 401 is provided on the top surface of the collection plate 41, and the sample collection groove 401 is formed by the depression of the top surface of the collection plate 41.

[0258] A sampling channel is further provided on the bottom wall of the sample collection groove 401, and the sampling channel is formed by the depression of the bottom wall of the sample collection groove 401 to the sample collection chamber 411.

[0259] The sample outlet channel 415 is also formed by the depression of the bottom wall of the sample collection groove 401 to the bottom of the sample collection chamber 411. The sample outlet channel 415 is located on the isolation part, and the top end of the sample outlet channel 415 is a vertical flow channel extending vertically upward, the middle area is a bent arc-shaped flow channel, and the bottom end is a horizontally extending channel, and the bottom end extends to the bottom of the sample collection chamber. This bent design of the sample outlet channel 415 can also make the sample adhere to the inner wall of the sample outlet channel 415 and be mixed during the flow process to reduce air bubbles.

[0260] A sewage outlet 417 is further provided at the bottom end of the sample collection chamber 411, and this opening is open towards the bottom end of the collection plate 41. Excess samples can flow into the toilet through the sewage flow channel 302.

[0261] The water inlet channel 413 is also formed by the depression of the bottom wall of the sample collection groove 401 to the clean water collection chamber 412, and the water inlet channel 413 is also located on the front side surface of the collection plate 41. A pipe can be inserted at the top end of the water inlet channel 413, and through this pipe, it is communicated with the clean water collection part. Similar to the previous embodiment, it will not be elaborated here.

[0262] The water outlet channel 414 is formed by bending and extending upward from the bottom of the clean water collection chamber 412 to the bottom wall of the sample collection groove 401. The water outlet channel 414 is formed by the depression of the rear side surface of the collection plate 41, and is also located on the isolation part. The water outlet channel 414 also has a bent shape. During the process of collecting clean water, the air bubbles in the clean water can also be reduced from entering the clean water flow channel of the flow channel plate 3.

[0263] The rear side of the isolation part is also provided with a sewage discharge channel 416. The top end of the sewage discharge channel 416 extends to the bottom wall of the sample collection tank 401 and is communicated with a sewage discharge adapter 3014 through a pipe. The bottom end of the sewage discharge channel 416 is communicated with the liquid outlet 421 of the inner cover plate 42. The inner cover plate 42 covers the rear side of the collection plate 41 and is used for attaching to the inner wall of the toilet. The liquid in the detection chamber can flow into the sewage discharge channel 416 from the sewage discharge flow channel 302 and the sewage discharge adapter 3014 in sequence, and then flow into the toilet from the liquid outlet 421.

[0264] This collector also includes two liquid level sensors, which are respectively installed in the clean water collection chamber 412 and the sample collection chamber 411 for sensing the liquid levels of clean water and samples.

[0265] A sample flow channel can be set on the flow channel plate 3, and the sample flow channel can be directly communicated with the sample collection chamber 411 through a sample adapter 3011. In another embodiment, two sample flow channels can also be set on the flow channel plate 3. The inner ends of the two sample flow channels are respectively communicated with two of the circumferential holes 32, and the outer ends are respectively communicated with two pipes through two sample adapters 3011.

[0266] Define the two sample flow channels as the upper sample flow channel 341 and the lower sample flow channel 342, and the pipes communicated with the two sample flow channels are respectively the upper sample pipe 344 and the lower sample pipe 345. Among them, the upper sample flow channel 341 is communicated with the upper sample pipe 344 through a sample adapter 3011, and the lower sample flow channel 342 is communicated with the lower sample pipe 345 through a sample adapter 3011.

[0267] One end of the lower sample pipe is communicated with the lower sample flow channel 342, and the other end is communicated with the sample outlet channel 415 of the sample collection chamber 411. A burette is arranged in the middle of the lower sample pipe, and this burette is defined as the sample burette 343. One end of the upper sample pipe is communicated with the upper sample flow channel 341, and the other end is communicated with the upper part of the sample burette 343. When a sample needs to be extracted, first align the rotor 6 with the circumferential hole 32 communicated with the upper sample flow channel 341, pump out the air in the upper sample flow channel 341, the upper sample pipe and the sample burette 343 and make a negative pressure in the sample burette 343, so that the sample can drip into the sample burette 343 from the sample collection chamber 411. Then rotate the rotor 6 to align the transfer channel with the circumferential hole 32 of the lower sample flow channel 342, pump out the air in the lower sample flow channel 342 and the lower sample pipe, and make the liquid in the sample burette 343 flow into the lower sample flow channel 342 from the lower sample pipe. This setting can ensure that the sample drips slowly into the lower sample flow channel 342 without generating bubbles.

[0268] Certainly, in another embodiment, an exhaust hole 418 is provided in the sample collection chamber 411. The upper sample flow channel 341 can communicate with the exhaust hole 418, and the lower sample flow channel 342 communicates with the sample outlet channel 415 of the sample collection chamber 411. At this time, the sample collection chamber 411 is similar to the above-mentioned sample burette, and the operation method is the same as above, so it will not be elaborated here.

[0269] The clear water flow channel of the flow channel plate 3 can also be provided with one, and this clear water flow channel directly communicates with the clear water collection chamber 412.

[0270] Certainly, two clear water flow channels are provided on the flow channel plate 3. Based on the same principle as the above two sample flow channels, the two clear water flow channels are respectively the upper clear water flow channel 351 and the lower clear water flow channel 352. The outer ends of the two clear water flow channels respectively communicate with the two circumferential holes 32. Similarly, the outer end of the lower clear water flow channel communicates with the clear water adapter tube 3012, and the clear water adapter tube 3012 is connected to the clear water collection chamber 412 through the upper clear water pipeline. A burette is also provided in the lower clear water pipeline, and this burette is defined as the clear water burette. The upper clear water pipeline communicates with the clear water burettes of the lower clear water pipeline.

[0271] The upper clear water flow channel 351 communicates with the clear water adapter tube 3012, and this clear water adapter tube 3012 is connected to the upper end of the clear water burette through the upper clear water pipeline.

[0272] When it is necessary to extract a sample, the rotor 6 needs to be aligned with the circumferential hole 32 communicating with the upper clear water flow channel 351 first, and the air in the upper clear water flow channel 351, the upper sample clear water pipeline and the clear water burette is pumped out to form a negative pressure in the clear water burette, so that the clear water can drip into the clear water burette from the clear water collection chamber 412. Then rotate the rotor 6 so that the transfer channel is aligned with the circumferential hole 32 of the lower clear water flow channel 352, and the air in the lower clear water flow channel 352 and the lower clear water pipeline is pumped out, and the liquid in the clear water burette flows into the lower clear water flow channel 352 from the lower clear water pipeline. With this setting, it can be ensured that the water slowly drips into the lower clear water flow channel 352 without generating bubbles.

[0273] The present invention also relates to a control method for a urine analyzer, such as Figure 30 and Figure 32As shown, the urine analyzer includes the above-mentioned kit, collector, rotary valve, and detection mechanism. The kit is also provided with multiple reagent chambers. The collector is also provided with a sample collection chamber and a clear water collection chamber. The rotary valve is the same as above and includes a microfluidic chip and a rotor. The microfluidic chip is provided with a common flow channel, an upper sample flow channel, a lower sample flow channel, multiple reagent flow channels, a detection flow channel, and an air flow channel. The outer end of the lower sample flow channel is connected to the sample collection chamber through a lower sample pipeline, and the lower sample pipeline is provided with a sample burette. The upper sample flow channel is connected to the upper end of the sample burette through an upper sample pipeline. The outer end of the common flow channel is connected to the clear water collection chamber through a driving pipeline or other pipelines. The outer ends of the multiple reagent flow channels are respectively connected to the multiple reagent chambers.

[0274] The rotor and the microfluidic chip are rotatably connected and are provided with a transfer channel. The inner end of the transfer channel is connected to the inner end of the common flow channel, and the outer end rotates with the rotor to be connected to the upper sample flow channel, the lower sample flow channel, the multiple reagent flow channels, the detection flow channel, and the air flow channel. That is to say, every time the rotary valve switches to the lower sample flow channel, the upper sample flow channel, the multiple reagent flow channels, the detection flow channel, or the air flow channel, the transfer channel is connected to the lower sample flow channel, the upper sample flow channel, the multiple reagent flow channels, the detection flow channel, or the air flow channel.

[0275] The detection mechanism is the same as above, and is provided with a detector and a detection chamber. The detection chamber is connected to the detection flow channel, and the detector is used to detect the sample in the detection chamber.

[0276] The control method of the urine analyzer includes the steps:

[0277] S1: The rotary valve switches to the sample flow channel, and the sample in the sample collection chamber is inhaled into the transfer channel. When the sample flow channel is directly connected to the sample collection chamber, the sample in the sample collection chamber can be directly inhaled into the transfer channel.

[0278] S2: The rotary valve switches to the detection flow channel, the transfer channel is connected to the detection flow channel, and the water in the clear water collection chamber is driven to flow into the common flow channel and the transfer channel. The water in the transfer channel is mixed with the sample in the transfer channel. The outer end of the common flow channel is connected to the clear water collection chamber, and the water in the clear water collection chamber can be pumped into the transfer channel from the common flow channel and mixed with the sample in the transfer channel.

[0279] S3: The rotary valve switches to the detection flow channel, and the mixed sample and water in the transfer channel are discharged.

[0280] S4: The water in the common flow channel is pushed into the detection chamber for detection. First, a comparative detection is performed as a reference for sample detection.

[0281] S5: The rotary valve switches to the sample flow channel, and a quantitative sample is extracted into the transfer channel.

[0282] S6: The rotary cutting valve switches to the reagent flow channel, the transfer channel communicates with the reagent flow channel, and quantitatively aspirates the reagent in the reagent chamber into the transfer channel.

[0283] S7: The rotary cutting valve switches to the detection flow channel, and pushes the reagent and sample in the transfer channel into the detection chamber;

[0284] S8: The detector starts to detect;

[0285] S9: Pushes the water in the common flow channel into the detection flow channel and discharges it from the detection chamber.

[0286] The outer end of the transfer channel of the rotor communicates with different flow channels as the rotary cutting valve switches. For example, when the rotary cutting valve switches to the reagent flow channel, the outer end of the transfer channel communicates with the reagent flow channel. The same is true when the rotary cutting valve switches to other flow channels, which will not be elaborated here.

[0287] Directly connect the common flow channel and the clean water collection chamber. After the detection is completed, the water in the common flow channel can be directly pushed into the detection chamber or the sample collection chamber for cleaning to improve the operation efficiency of the urine analyzer. Moreover, the common flow channel and the clean water collection chamber are directly connected. When it is necessary to extract samples and reagents, first fill the common flow channel and the drive pipeline with clean water, then fill the transfer channel with air to isolate the water in the common flow channel from the sample or reagent. After the pump is started, use the clean water and a small part of the air in the transfer channel to drive the reagent and sample to move. Since the clean water is not easily compressed, the sample or reagent can be more accurately extracted into the microfluidic chip, and the detection accuracy is improved.

[0288] As a preferred solution, step S1 includes:

[0289] S1.1: The rotary cutting valve switches to the upper sample flow channel, the transfer channel communicates with the upper sample flow channel, and aspirates the air in the upper sample flow channel and the sample burette, a negative pressure is formed in the sample burette, and the sample in the sample collection chamber flows into the sample burette;

[0290] S1.2: Switch the rotary cutting valve to make the transfer channel communicate with the lower sample flow channel, and drive the sample in the sample burette to flow into the transfer channel.

[0291] First aspirating the air in the sample burette can reduce the bubbles of the sample from entering the transfer channel.

[0292] Optionally, the urine analyzer further includes a first pump and a second pump, where the first pump is a peristaltic pump and the second pump is a plunger pump. The two ends of the hose of the peristaltic pump are respectively connected to two pipelines. Among the two pipelines, the other end of one pipeline is communicated with the clear water collection chamber, and the other end of the other pipeline is connected to the plunger pump. That is to say, the two pipelines and the driving pipeline are connected in series to communicate the clear water collection chamber and the common flow channel. The logic diagram of this embodiment can be referred to Figure 32 , this embodiment is different from the above embodiments where two driving pipelines are respectively connected to the peristaltic pump and the plunger pump. This embodiment does not have two driving pipelines, so there is no need for the above-mentioned peristaltic pump adapter post and driving flow channel. Moreover, the common flow channel and the clear water collection chamber of this embodiment are directly communicated, so there is no need to set up the upper clear water flow channel and the lower clear water flow channel.

[0293] In step S1.1, the peristaltic pump rotates forward to extract the air in the upper sample flow channel and the sample burette;

[0294] In step S1.2, the peristaltic pump rotates forward to suck the sample in the sample burette into the transfer channel;

[0295] In step S2, the peristaltic pump rotates reversely and pumps the water in the clear water collection chamber into the common flow channel and the transfer channel;

[0296] In step S3: The rotary valve switches to the air flow channel, the transfer channel is communicated with the air flow channel. After the control module controls the plunger pump to rotate forward to suck air, the rotary valve switches to the detection flow channel, and the plunger pump resets to discharge the mixed sample and water in the transfer channel from the detection flow channel and the detection chamber;

[0297] In step S4, the peristaltic pump rotates reversely to pump the water in the common flow channel from the detection flow channel; then the rotary valve switches to the air flow channel, the plunger pump rotates forward to suck a fixed amount of air into the transfer channel, the rotary valve switches to the detection flow channel again, and the plunger pump resets to push the water in the detection flow channel into the detection chamber for detection;

[0298] In step S5, the plunger pump rotates forward to quantitatively extract the sample into the transfer channel;

[0299] In step S6, the plunger pump rotates forward and quantitatively sucks the reagent in the reagent chamber into the transfer channel;

[0300] In step S7, the plunger pump resets and pushes the reagent and sample in the transfer channel into the detection chamber;

[0301] In step S9, the rotary cutting valve switches to the detection flow channel, the peristaltic pump reverses and pushes the water in the common flow channel into the detection flow channel, and discharges it from the detection cavity.

[0302] Optionally, in step S5, it is first determined whether the sample needs to be diluted;

[0303] If dilution is required, the rotary cutting valve first switches to the detection flow channel, and the peristaltic pump reverses first to push a fixed amount of clear water into the detection flow channel. Then the rotary cutting valve switches to the air flow channel, and the plunger pump rotates forward to suck a fixed amount of air into the transfer channel. This part of the air is used to isolate the water in the common flow channel. After the rotary cutting valve switches to the detection flow channel again, the plunger pump rotates forward to suck the clear water in the detection flow channel into the transfer channel. At this time, the air separates the clear water at the outer end of the detection flow channel from the clear water in the transfer channel. The rotary cutting valve switches to the lower sample flow channel, the plunger pump rotates forward and quantitatively extracts the sample in the lower sample flow channel into the transfer channel to mix with the water in the transfer channel. Then the rotary cutting valve switches to the air flow channel, and the plunger pump rotates forward again to suck a fixed amount of air into the transfer channel. This part of the air is used to isolate the water at the outer end of the detection flow channel from the water and sample in the transfer channel. The rotary cutting valve switches to the detection flow channel, and the plunger pump resets and pushes the diluted sample into the transfer channel.

[0304] If dilution is not required, the rotary cutting valve switches to the air flow channel, first quantitatively sucks air, and then the rotary cutting valve switches to the lower sample flow channel, and the plunger pump rotates forward and quantitatively extracts the sample into the transfer channel.

[0305] Optionally, it is determined whether multiple reagents need to be extracted. If one reagent needs to be extracted, step S7 is carried out after step S6; if multiple reagents need to be extracted, step S6 is repeated multiple times, and the rotary cutting valve switches to different reagent flow channels as needed to extract different reagents into the transfer channel. Some detection items require mixing of multiple reagents, so step S6 needs to be repeated to suck different reagents into the transfer channel.

[0306] It should be understood that whether the detection item needs to be diluted, the amount of diluted sample required for the detection, the type and amount of reagents required are set in the control module. Therefore, after the detection is started, the control module will judge the process to be carried out according to the detection item.

[0307] As a preferred solution, the rotary cutting valve is provided with a mixing cavity, and the mixing cavity is located on the path of the detection flow channel and communicates with the detection flow channel.

[0308] In step S8, after the rotary cutting valve switches to the detection flow path, the plunger pump resets to first push the reagent and sample in the transfer channel into the mixing chamber to be mixed into a mixed liquid, and then the plunger pump pushes the mixed liquid into the detection chamber.

[0309] Further, in step S8, the plunger pump rotates forward for a preset time and then resets for a preset time. After mixing the reagent and sample in the mixing chamber into the mixed liquid, the plunger pump then pushes the mixed liquid into the detection chamber.

[0310] Further, the mixing chamber includes a mixing bend and a mixing chamber that communicate with each other, and the mixing bend is a curved flow path.

[0311] The plunger pump rotates forward for a preset time and then resets for a preset time. After continuously flowing and mixing the reagent and sample in the mixing bend and the mixing chamber into a mixed liquid, the plunger pump resets and then pushes the mixed liquid into the detection chamber.

[0312] Optionally, in step S8, after the plunger pump resets to push the reagent and sample in the transfer channel into the mixing chamber to be mixed into the mixed liquid, the rotary cutting valve switches to the air flow path, the plunger pump rotates forward and quantitatively sucks air into the transfer channel, and then the rotary cutting valve switches to the detection flow path again. The plunger pump resets to push the mixed liquid in the mixing chamber into the detection chamber. When the stroke of the plunger pump is insufficient, it is necessary to suck a certain amount of air and push the mixed liquid in the mixing chamber into the detection chamber.

[0313] Optionally, in step S9, the peristaltic pump rotates in reverse to push the water in the common flow path into the detection flow path and form waste liquid with the sample and reagent in the detection chamber. The rotary cutting valve switches to the air flow path, the plunger pump rotates forward to suck air into the transfer channel, and then the rotary cutting valve switches to the detection flow path again. The plunger pump resets and discharges the waste liquid in the detection chamber. After the detection is completed, the water in the common flow path is directly pushed into the detection chamber to discharge the waste liquid.

[0314] Optionally, after step S9, it further includes step S10: the peristaltic pump rotates in reverse to push the water in the common flow path into the detection flow path and discharge it from the detection chamber.

[0315] Then the rotary cutting valve switches to the lower sample flow path, and the peristaltic pump rotates in reverse to push the water in the common flow path into the sample collection chamber from the lower sample flow path and discharge it from the sample collection chamber. The water in the common flow path is pushed into the sample collection chamber and the detection chamber, and the detection chamber is connected to the sewage discharge channel of the collector, so the waste liquid is discharged from the collection chamber.

[0316] The order of step S10 can also be changed. The rotary valve can first be switched to the lower sample flow channel, and the peristaltic pump is reversed to push the water in the common flow channel into the sample collection cavity through the lower sample flow channel and discharge it from the sample collection cavity.

[0317] The peristaltic pump is reversed to push the water in the common flow channel into the detection flow channel and discharge it from the detection cavity.

[0318] Optionally, after step S10, there is also step S11: The rotary valve is switched to the detection flow channel, and the peristaltic pump is reversed to push all the remaining water in the common flow channel into the detection flow channel and discharge it from the detection cavity.

[0319] As a preferred solution, a first sensor is provided in the sample burette;

[0320] The urine analyzer further includes a control module, and the control module is connected to the peristaltic pump, the plunger pump, the rotary valve and the first sensor;

[0321] Before step S2, there is also a step: The first sensor sends the sample volume information sensed in the sample burette to the control module. If the sample volume information does not meet the requirements, the process ends. If it meets the requirements, then step S2 is carried out;

[0322] In step S8, after the detector detects, it sends the detection result to the control module. After step S9, if the detection result is abnormal, the control module restarts steps S1 to S9; if the detection result is normal, then the next detection item is carried out.

[0323] The urine analyzer further includes a warning light, and the warning light is connected to the control module. After step S9, if the detection results are abnormal for two consecutive times, the control module controls the warning light to give a warning.

[0324] Preferably, a second sensor is provided in the clean water collection cavity, and the second sensor is also connected to the control module. Before step S3, there is also a step: The second sensor sends the clean water volume detected in the clean water collection cavity to the control module. If it does not meet the requirements, the control module controls the process to end; if it meets the requirements, then step S4 is carried out.

[0325] After the urine analyzer operates for several months or a preset number of operating times is set, the reagent kit needs to be replaced. Before replacing the reagent kit, the reagent flow channel needs to be cleaned. The specific steps are as follows:

[0326] S01: The rotary valve is switched to the detection flow channel, and the peristaltic pump is reversed to push the water in the clean water collection cavity into the detection flow channel through the common flow channel and the transfer channel in sequence;

[0327] S02: The rotary valve switches to the air flow channel, and the plunger pump or the peristaltic pump rotates forward to suck air into the transfer channel;

[0328] S03: The rotary valve switches to the washing flow channel, and the plunger pump rotates forward to suck a fixed amount of washing liquid into the transfer channel;

[0329] S04: The rotary valve switches to the detection flow channel again. The plunger pump resets and pushes the washing liquid in the transfer channel into the detection flow channel and mixes it with the water in the detection flow channel to form a diluted washing liquid. Then the peristaltic pump rotates in reverse to suck the diluted washing liquid in the detection flow channel into the transfer channel;

[0330] S05: The rotary valve switches to one of the reagent flow channels, and the peristaltic pump rotates in reverse to push the diluted washing liquid in the transfer channel into the reagent flow channel and the reagent chamber; The rotary valve sequentially switches multiple reagent flow channels, and the peristaltic pump sequentially pushes the diluted washing liquid in the transfer channel into multiple reagent chambers;

[0331] S06: The rotary valve sequentially switches to multiple reagent flow channels, and the peristaltic pump sequentially rotates in reverse to push the clear water in the common flow channel into multiple reagent flow channels and multiple reagent chambers;

[0332] S07: Replace with a new reagent kit.

[0333] As a preferred solution, in step S01: The rotary valve switches to the detection flow channel, and the peristaltic pump rotates in reverse to push the water in the clear water collection chamber into the transfer channel and then into the mixing chamber in sequence from the common flow channel;

[0334] In step S04: The rotary valve switches to the detection flow channel again. The plunger pump resets and pushes the washing liquid in the transfer channel into the detection flow channel and then into the mixing chamber. The peristaltic pump rotates forward for a preset time and then rotates in reverse for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid. Then the peristaltic pump rotates in reverse to suck the diluted washing liquid in the detection flow channel into the transfer channel.

[0335] That is, the detergent and the clear water are mixed in the mixing chamber and then pushed into multiple reagent flow channels and reagent chambers.

[0336] Optionally, after the urine analyzer has been operating for several months or a preset number of times, it also needs to be cleaned regularly, including the steps:

[0337] S001: The rotary valve switches to the detection flow channel, and the peristaltic pump rotates in reverse to push the water in the clear water collection chamber into the transfer channel and then into the detection flow channel in sequence from the common flow channel;

[0338] S002: The rotary valve switches to the air flow channel, and the plunger pump or the peristaltic pump rotates forward to absorb air into the transfer channel;

[0339] S003: The rotary valve switches to the washing flow channel, and the plunger pump rotates forward to suck a fixed amount of washing liquid into the transfer channel;

[0340] S004: The rotary valve switches to the detection flow channel again, the plunger pump resets and pushes the washing liquid in the transfer channel into the detection flow channel and mixes it with the water in the detection flow channel to form a diluted washing liquid;

[0341] S005: The peristaltic pump rotates in reverse to suck the diluted washing liquid in the detection flow channel into the transfer channel;

[0342] S005: The rotary valve switches to the lower sample flow channel, and the peristaltic pump rotates in reverse to push the diluted washing liquid in the transfer channel into the sample collection cavity;

[0343] S006: Repeat steps S001 to S004, and the peristaltic pump rotates in reverse to push the diluted washing liquid in the detection flow channel into the detection cavity;

[0344] S007: Wait for a preset time;

[0345] The rotary valve first switches to the lower sample flow channel, the peristaltic pump rotates in reverse to push the water in the common flow channel into the sample collection cavity and then discharges it. Then the rotary valve switches to the detection flow channel, and the peristaltic pump rotates in reverse to push the water in the common flow channel into the detection cavity and then discharges it; or

[0346] After waiting for a preset time, then the rotary valve switches to the detection flow channel, the peristaltic pump rotates in reverse to push the water in the common flow channel into the detection cavity and then discharges it. After that, the rotary valve switches to the lower sample flow channel, and the peristaltic pump rotates in reverse to push the water in the common flow channel into the sample collection cavity and then discharges it.

[0347] During the cleaning process, the diluted washing liquid is soaked in multiple flow channels, the sample collection cavity and the detection cavity to increase the cleaning reaction duration and cleaning intensity.

[0348] As a preferred solution, the diluted washing liquid needs to be mixed in the mixing cavity. That is to say, step S001: The rotary valve switches to the detection flow channel, and the peristaltic pump rotates in reverse to push the water in the clean water collection cavity into the transfer channel and then into the mixing cavity in sequence from the common flow channel;

[0349] Step S004: The rotary valve switches to the detection channel again. The plunger pump resets and pushes the washing liquid in the transfer channel into the mixing chamber. The peristaltic pump rotates forward for a preset time and then rotates backward for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid. Then, the peristaltic pump rotates backward to suck the diluted washing liquid in the detection channel into the transfer channel.

[0350] The control module is also connected to the peristaltic pump 91, the plunger pump 92, and the motor, and can control the operation of the peristaltic pump 91, the plunger pump 92, and the motor according to the information of the liquid level sensors in the sample collection chamber 411 and the clean water collection chamber 412. For example, after receiving the signal from the liquid level sensor in the sample collection chamber 411, the control module can drive the motor to drive the rotor 6 to rotate, so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 communicating with the sample channel.

[0351] The present invention also relates to a method for using a microfluidic chip, as Figure 31 shown, the flow channel plate 3 is provided with the above-mentioned sample channel, reagent channel 37, detection channel 38, and common channel 33. The common channel 33 is operably connected to the sample channel, the reagent channel 37, and the detection channel 38. The mixing chamber 39 is located on the path of the detection channel 38 and has an outlet and an inlet. The mixing chamber 39 includes a mixing bend 392 and a mixing chamber 391. The mixing bend 392 is a curved flow channel and is located on the path of the detection channel 38. The width dimension of the mixing chamber 391 is larger than the diameter dimension of the detection channel 38.

[0352] The method for using the flow channel plate 3 includes the steps:

[0353] S11: Drive the sample in the sample channel into the common channel 33;

[0354] S12: Drive the reagent in the reagent channel 37 into the common channel 33;

[0355] S13: Drive the sample and the reagent in the common channel 33 to enter the inlet of the mixing chamber 39 from the detection channel 38, flow into the mixing chamber 391 after entering the mixing bend 392 from the inlet of the mixing chamber 39 to form a mixed liquid, and then drive the mixed liquid to flow into the detection channel 38 again from the outlet of the mixing chamber 39 and flow out from the detection channel 38.

[0356] The above-mentioned sample channel is connected to the sample collection chamber, the reagent channel 37 is connected to the reagent chamber 21 containing the reagent, and the detection channel 38 is connected to the detection chamber.

[0357] The common flow channel 33 can be connected to the sample flow channel, the reagent flow channel 37 or the detection flow channel 38 through a three-way valve or other valves. The air in the common flow channel 33 can be pumped out by a peristaltic pump 91 or a plunger pump 92 to form a negative pressure, and then the sample in the above-mentioned sample flow channel or the reagent in the reagent flow channel 37 can be driven into the common flow channel 33.

[0358] Optionally, the mixing chamber 391 is located above the mixing bend 392, and the inlet of the mixing chamber 39 is below the outlet of the mixing chamber 39;

[0359] In step S13, the sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing chamber 39 from the detection flow channel 38, flow into the mixing chamber 391 after entering the mixing bend 392 from the inlet of the mixing chamber 39, and then the mixed liquid flows back into the mixing bend 392 from the mixing chamber 39, and the sample and reagent flow back by gravity. Then drive the mixing bend 392 to flow into the mixing chamber 39 from the mixing bend 392, and finally drive the mixed liquid to enter the detection flow channel 38 again from the mixing chamber 39 and flow out from the detection flow channel 38.

[0360] Optionally, the mixing chamber 391 is located above the mixing bend 392; in step S3, the sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing chamber 39 from the detection flow channel 38, flow into the mixing chamber 391 after entering the mixing bend 392 from the inlet of the mixing chamber 39, and then the mixed liquid flows back into the mixing bend 392 from the mixing chamber 391. After staying for 1 s - 2 s, then drive the mixing bend 392 to flow into the mixing chamber 391 from the mixing bend 392, and finally drive the mixed liquid to enter the detection flow channel 38 again from the mixing chamber 391 and flow out from the detection flow channel 38.

[0361] During the mixing process of the sample and reagent, staying for 1 s - 2 s can improve the mixing effect.

[0362] As a preferred solution, the mixing chamber 39 includes a plurality of mixing bends 392 and a plurality of mixing chambers 391, and the plurality of mixing bends 392 and the plurality of mixing chambers 391 are arranged at intervals and communicate with each other;

[0363] In step S13, the sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing chamber 39 from the detection flow channel 38, enter a plurality of mixing bends 392 and a plurality of mixing chambers 39 from the inlet of the mixing chamber 39, and finally drive the mixed liquid to flow out from the detection flow channel 38.

[0364] Further, the mixing bend 392 is an S-shaped bend and includes at least two horizontal flow channels and at least one turning flow channel 394, and any one turning flow channel 394 is located at both ends of the two horizontal flow channels;

[0365] The horizontal flow channel extends in the horizontal direction. The turning flow channel 394 includes a curved inner arc 395 and an outer arc 396. Both the inner arc 395 and the outer arc 396 are arc-shaped, and the inner diameter of the inner arc 395 is smaller than the inner diameter of the outer arc 396.

[0366] Optionally, the inner wall of the mixing chamber 391 includes a first arc surface 397 and a second arc surface 398 opposite to the first arc surface 397. The first arc surface 397 and the second arc surface 398 are arc surfaces protruding towards the outside.

[0367] Optionally, each mixing chamber 391 communicates with the horizontal flow channels of two mixing bends 392, and the two horizontal flow channels are radially symmetrically arranged at the top and bottom of the mixing chamber 391.

[0368] In step S13, the sample and reagent in the common flow channel 33 are driven to enter the mixing cavity 39 from the detection flow channel 38, enter a mixing bend 392 from the entrance of the mixing cavity 39 and then flow into the mixing chamber 391, and then flow into the other mixing bend 392 from the mixing cavity 39 to form a mixed liquid. After staying for 1 s - 2 s, the mixed liquid flows back into the mixing chamber 391, and the mixed liquid is driven to be discharged from the mixing bend 392.

[0369] In one embodiment, each mixing chamber has a sample inlet and a sample outlet respectively. The sample inlet and the sample outlet of each mixing cavity are respectively communicated with the adjacent mixing bends, and the sample inlet of each mixing cavity is located above the sample outlet.

[0370] In step S13, after the sample and reagent enter the mixing cavity, they flow through one of the mixing bends and enter the mixing cavity through an adjacent sample inlet, and then flow into the other mixing bend from the sample outlet. The sample and reagent continuously flow in multiple mixing chambers and multiple mixing bends to form the mixed liquid.

[0371] The microfluidic chip can be placed in the vertical direction. That is to say, when the sample and reagent flow from bottom to top, the influence of gravity does not need to be considered, so there will be no residue problem in the mixing chamber.

[0372] Optionally, the flow channel plate 3 is further provided with a clean water flow channel, and the common flow channel 33 can be communicated with the clean water flow channel through the transfer channel of the rotor 6.

[0373] After step S13, there is further step S14: driving the water in the clean water flow channel to enter the common flow channel 33, then driving the water in the common flow channel 33 to enter the detection flow channel 38, then entering the mixing cavity 39 from the entrance of the mixing cavity 39, and then entering the detection flow channel 38 again from the outlet of the mixing cavity 39 and being discharged from the detection flow channel 38.

[0374] As a preferred solution, the flow channel plate 3 is further provided with a central hole 31 and a plurality of circumferential holes 32 arranged around the central hole 31. The central hole 31 penetrates through the flow channel plate 3 and communicates with the inner end of the common flow channel 33. The plurality of circumferential holes 32 are arranged circumferentially with the central hole 31 as the center. The inner end of the common flow channel 33 communicates with the central hole 31, and the outer end is connected to a pump through a drive pipe. The inner end of the sample flow channel communicates with one of the circumferential holes 32. The inner end of the reagent flow channel 37 communicates with one of the circumferential holes 32. The inner end of the detection flow channel 38 communicates with one of the circumferential holes 32;

[0375] The central hole 31 communicates with the inner end of the transfer channel of a rotor 6, and the outer end of the transfer channel can communicate with any one of the circumferential holes 32 as the rotor 6 rotates.

[0376] In step S11, the rotor 6 rotates, and the transfer channel communicates with the sample flow channel through one of the circumferential holes 32. The pump pumps out the air in the common flow channel 33 and the sample flow channel, and pumps the sample in the sample flow channel into the common flow channel 33;

[0377] In step S12, the rotor 6 rotates, and the transfer channel communicates with the reagent flow channel 37 through one of the circumferential holes 32. The pump pumps out the air in the common flow channel 33 and the reagent flow channel 37, and pumps the sample in the reagent flow channel 37 into the common flow channel 33;

[0378] In step S13, the rotor 6 rotates, and the transfer channel communicates with the detection flow channel 38 through one of the circumferential holes 32; the pump drives the sample and the reagent in the common flow channel 33 to enter the inlet of the mixing chamber 39 from the detection flow channel 38, flows into the mixing chamber 391 after entering the mixing bend 392 from the inlet of the mixing chamber 39 to form a mixed liquid, and then drives the mixed liquid to flow into the detection flow channel 38 again from the outlet of the mixing chamber 39 and flows out from the detection flow channel 38.

[0379] As another preferred solution, the flow channel plate 3 is provided with two sample flow channels, namely an upper sample flow channel 341 and a lower sample flow channel 342. The inner ends of the lower sample flow channel 342 and the upper sample flow channel 341 communicate with two of the circumferential holes 32 respectively. The lower sample flow channel communicates with the sample collection chamber for holding the sample through a lower sample pipe, and a sample burette is provided on the lower sample pipe. The upper sample flow channel 341 communicates with the sample burette through an upper sample pipe;

[0380] In step S11, the rotor 6 rotates, aligns the outer end 62 of the transfer channel with the circumferential hole 32 communicating with the upper sample flow channel 341, and the pump cooperates with the drive pipe to pump out the air in the common flow channel 33, the transfer channel, the upper sample flow channel 341 and the sample burette.

[0381] Then the rotor 6 rotates, aligns the outer end 62 of the transfer channel with the circumferential hole 32 communicating with the lower sample flow channel 342, and pumps the sample in the sample collection chamber from the lower sample flow channel 342 to the common flow channel 33.

[0382] A sample burette is provided to reduce the inflow of air bubbles in the sample collection chamber into the sample flow channel.

[0383] Optionally, the flow channel plate 3 is further provided with a clear water flow channel, and the clear water flow channel communicates with one circumferential hole 32.

[0384] After step S13, there is further step S14: the rotor 6 rotates, the transfer channel communicates with the clear water flow channel through one circumferential hole 32, the pump drives the water in the clear water flow channel into the common flow channel 33, then drives the water in the common flow channel 33 into the detection flow channel 38, then enters the mixing chamber 39 from the inlet of the mixing chamber 39, and then enters the detection flow channel 38 again from the outlet of the mixing chamber 39 and is discharged from the detection flow channel 38.

[0385] Preferably, the flow channel plate 3 is provided with an upper clear water flow channel 351 and a lower clear water flow channel 352. The inner ends of the upper clear water flow channel 351 and the lower clear water flow channel 352 are respectively communicated with two circumferential holes 32. The lower clear water flow channel is communicated with a clear water collection chamber for holding water through a lower clear water pipe, and a clear water burette is provided on the lower clear water pipe. The upper clear water flow channel 351 is communicated with the clear water burette through an upper clear water pipe.

[0386] After step S13, there is further step S14: the rotor 6 rotates, aligns the outer end 62 of the transfer channel with the circumferential hole 32 communicating with the upper clear water flow channel 351, and the pump pumps the air in the common flow channel 33, the transfer channel, the upper clear water flow channel 351 and the clear water burette to the outside;

[0387] Then the rotor 6 rotates, aligns the outer end 62 of the transfer channel with the circumferential hole 32 communicating with the lower clear water flow channel 352, pumps the sample in the sample collection chamber from the lower clear water flow channel 352 to the common flow channel 33, the rotor 6 rotates, aligns the common flow channel 33 with the circumferential hole 32 of the detection flow channel 38, and discharges the water in the common flow channel 33 through the detection flow channel 38 in sequence.

[0388] Optionally, the flow channel plate 3 is further provided with an air flow channel 36, and the inner end of the air flow channel 36 communicates with another circumferential hole 32.

[0389] In step S3, before the rotor 6 rotates and the transfer channel communicates with the detection flow channel 38 through one circumferential hole 32; the rotor 6 rotates so that the transfer channel aligns with the circumferential hole 32 communicating with the air, so that the common flow channel 33 communicates with the air flow channel 36, and the pump extracts air from the air flow channel 36 into the common flow channel 33.

[0390] Then the rotor 6 rotates, and the middle transfer channel communicates with the detection channel 38 through one of the circumferential holes 32; the sample and reagent in the pump-driven common channel 33 enter the inlet of the mixing chamber 39 from the detection channel 38, enter the mixing bend 392 from the inlet of the mixing chamber 39 and then flow into the mixing chamber 391 to form a mixed liquid, and then drive the mixed liquid to flow into the detection channel 38 again from the outlet of the mixing chamber 39 and flow out from the detection channel 38.

[0391] The flow channel plate 3 of the present invention can also be adapted to other urine analyzers 100. By configuring the above-mentioned pump or rotor 6, the sample and reagent can be mixed in the flow channel plate 3 to reduce bubbles and increase the detection accuracy.

[0392] The preferred embodiments of the present invention have been described in detail above. However, it should be understood that if necessary, aspects of the embodiments can be modified to adopt aspects, features, and concepts of various patents, applications, and publications to provide additional embodiments.

[0393] In view of the above detailed description, these and other changes can be made to the embodiments. Generally speaking, in the claims, the terms used should not be construed as being limited to the specific embodiments disclosed in the specification and claims, but should be understood to include all possible embodiments and the entire equivalent scope enjoyed by these claims.

[0394] Those of ordinary skill in the art can understand that the above embodiments are specific embodiments for implementing the present invention. In actual applications, various changes can be made in form and details without departing from the spirit and scope of the present invention.

Claims

1. A method for controlling a urine tester, characterized in that: The urine tester comprises: A reagent kit, wherein the reagent kit is provided with a plurality of reagent chambers, and reagents are placed in the reagent chambers; A collector, wherein the collector is provided with a sample collection chamber and a clean water collection chamber; A rotary shear valve, wherein the rotary shear valve is provided with a common flow channel, a sample flow channel, a plurality of reagent flow channels, a detection flow channel, an air flow channel and a transfer channel; the sample flow channel is connected to the sample collection chamber through a lower sample pipe; the outer end of the common flow channel is connected to the clean water collection chamber through a driving pipe; the plurality of reagent flow channels are respectively connected to the plurality of reagent chambers; one end of the transfer channel is connected to the inner end of the common flow channel, and the other end is operably connected to the sample flow channel, the plurality of reagent flow channels, the detection flow channel and the air flow channel; A detection mechanism, wherein a detector and a detection cavity are provided in the detection mechanism, and the detection cavity is communicated with the detection flow channel; The sample flow channel comprises: a lower sample flow channel, the lower sample flow channel being connected to the sample collection chamber through a lower sample pipe, the lower sample pipe being provided with a sample burette; and an upper sample flow channel, the upper sample flow channel being in communication with the upper portion of the sample burette; Includes steps: S1: comprising step S1.1: the rotary cutting valve is switched to the upper sample flow channel, the transfer channel is connected to the upper sample flow channel, the air in the upper sample flow channel and the sample burette is extracted, a negative pressure is formed in the sample burette, and the sample in the sample collection chamber flows into the sample burette; S1.2: Switch the rotary cutting valve to connect the transfer channel with the lower sample flow channel, and drive the sample in the sample burette to flow into the transfer channel; S2: the rotary cutting valve is switched to the detection flow channel, the transfer channel is connected to the detection flow channel, the water in the clean water collection chamber is driven to flow into the common flow channel and the transfer channel, and the water in the transfer channel is mixed with the sample in the transfer channel; S3: the rotary cutting valve switches to the detection channel to discharge the mixed sample and water in the transfer channel; S4: Pushing the water in the common flow channel into the detection chamber for detection; S5: The common flow channel and the driving pipeline are first filled with water, the rotary cutting valve switches the air flow channel, and the air is quantitatively sucked into the transfer channel. Then, the rotary cutting valve switches to the lower sample flow channel, and the sample is quantitatively drawn into the transfer channel. S6: the rotary cutting valve is switched to the reagent flow channel, the transfer channel is connected to the reagent flow channel, and the reagent in the reagent chamber is quantitatively sucked into the transfer channel; S7: the rotary cutting valve switches to the detection channel to push the reagent and sample in the transfer channel into the detection cavity; S8: the detector starts detecting; S9: Push the water in the common flow channel into the detection flow channel and discharge it from the detection cavity.

2. The control method of the urine tester according to claim 1, characterized in that: The urine tester also includes: A first pump, the first pump is connected to two pipes, one of which is in communication with the clean water collection chamber; and a second pump, the second pump being connected to another of the pipelines and a drive pipeline, the drive pipeline being in communication with the common flow channel; In step S1.1, the first pump is started to extract air from the upper sample flow channel and the sample burette; In step S1.2, the first pump is started to suck the sample in the sample burette into the transfer channel; In step S2, the first pump is started to pump water in the clean water collection chamber into the common flow channel and the transfer channel; In step S3: the rotary cutting valve is switched to the air flow channel, the transfer channel is connected to the air flow channel, the control module controls the second pump to start to absorb air, the rotary cutting valve is switched to the detection flow channel, the second pump is started, and the mixed sample and water in the transfer channel are discharged from the detection flow channel and the detection chamber; In step S4, the first pump is started to push the water in the common flow channel into the detection flow channel; then the rotary cut valve is switched to the air flow channel, the second pump is started to suck a certain amount of air into the transfer channel, the rotary cut valve is switched to the detection flow channel again, the second pump is started to push the water in the detection flow channel into the detection chamber for detection; In step S5, the second pump is started to quantitatively extract the sample into the transfer channel; In step S6, the second pump is started to quantitatively draw the reagent in the reagent chamber into the transfer channel; In step S7, the second pump is started and pushes the reagent and sample in the transfer channel into the detection chamber; In step S9, the rotary cutting valve is switched to the detection flow channel, the first pump is started and pushes the water in the common flow channel into the detection flow channel, and then discharges the water from the detection cavity.

3. The control method of the urine tester according to claim 2, characterized in that: Determine whether it is necessary to extract multiple reagents. If one reagent needs to be extracted, perform step S7 after step S6; if multiple reagents need to be extracted, repeat step S6 multiple times. After each reagent extraction, the rotary cutting valve needs to be switched to the detection channel, and after the reagent is pushed into the detection channel, the rotary cutting valve is switched to a different reagent channel to extract the reagent again.

4. The control method of the urine tester according to claim 2, characterized in that: The rotary cutting valve is provided with a mixing chamber, and the mixing chamber is located on the path of the detection flow channel and is connected with the detection flow channel; In step S7, after the rotary cutting valve is switched to the detection channel, the second pump is started to push the reagent and sample in the transfer channel into the mixing chamber to mix into a mixed liquid, and then the second pump is started to push the mixed liquid into the detection chamber.

5. The control method of the urine tester according to claim 4, characterized in that: In step S7, the second pump starts for a preset time, then resets the preset time, mixes the reagent and sample in the mixing chamber into the mixed liquid, and then the second pump pushes the mixed liquid into the detection chamber.

6. The control method of the urine tester according to claim 5, characterized in that: The mixing cavity comprises a mixing bend and at least one mixing chamber which are connected to each other, and the mixing bend is a curved flow channel; In step S7, the second pump is started for a preset time, and then resets the preset time. After the reagent and the sample are continuously mixed in the mixing curve and the mixing chamber to form a mixed liquid, the second pump is started to push the mixed liquid into the detection cavity.

7. The control method of the urine tester according to claim 6, characterized in that: In step S7, the second pump is reset, and after the reagents and samples in the transfer channel are pushed into the mixing chamber to be mixed into the mixed liquid, the rotary cutting valve is switched to the air flow channel, the second pump is started and quantitatively draws air into the transfer channel, and then the rotary cutting valve is switched to the detection flow channel again, and the second pump is reset to push the mixed liquid in the mixing chamber into the detection chamber.

8. The control method of the urine tester according to claim 7, characterized in that: In step S9, the first pump starts and pushes the water in the common flow channel into the detection flow channel, and mixes with the sample and reagent in the detection chamber to form waste liquid; the rotary cutting valve switches to the air flow channel, the second pump starts, draws air into the transfer channel, and then the rotary cutting valve switches to the detection flow channel again, the second pump resets and discharges the waste liquid from the detection chamber.

9. The control method of the urine tester according to claim 7, characterized in that: The step S10 is also included: the rotary cutting valve is switched to the lower sample flow channel, the first pump is started, and the water in the common flow channel is pushed from the lower sample flow channel into the sample collection cavity, and discharged from the sample collection cavity; or Before step S9, the method further includes the following steps: the rotary cutting valve is switched to the lower sample flow channel, the first pump is started, and the water in the common flow channel is pushed from the lower sample flow channel into the sample collection cavity and discharged from the sample collection cavity.

10. The control method of the urine tester according to claim 9, characterized in that: Afterwards, the method further includes step S11: the rotary cutting valve is switched to the detection flow channel, the first pump is started, and all the remaining water in the common flow channel is pushed into the detection flow channel and discharged from the detection cavity.

11. The control method of the urine tester according to claim 2, characterized in that: A first sensor is disposed in the sample burette; The urine test instrument further comprises a control module, wherein the control module is connected to the first pump, the second pump, the rotary cutting valve and the first sensor; Before step S2, the method further includes the following steps: the first sensor sends the sample volume information in the sample burette sensed by the first sensor to the control module. If the sample volume information does not meet the requirements, the process is terminated. If the sample volume information meets the requirements, step S2 is executed. In step S8, the detector sends the detection result to the control module after detection.

12. The control method of the urine tester according to claim 11, characterized in that: After step S9, if the test result is abnormal, steps S1 to S9 are repeated; if the test result is normal, the next test item is performed.

13. The control method of the urine tester according to claim 11, characterized in that: The urine test instrument further comprises a warning light, and the warning light is electrically connected to the control module; After step S9, if the detection results are abnormal for two consecutive times, the control module controls the warning light to give a warning.

14. The control method of the urine tester according to claim 11, characterized in that: A second sensor connected to the control module is provided in the clean water collection chamber; The method before step S3 also includes the following steps: the second sensor detects the amount of clean water in the clean water collection chamber and sends it to the control module. If the amount does not meet the requirements, the control module controls the process to end. If the requirements are met, proceed to step S4.

15. The control method of the urine tester according to claim 2, characterized in that: The rotary cutting valve is also provided with a washing flow channel; The urine test instrument also includes a washing liquid and a washing chamber containing the washing liquid; After the steps S1 to S9 are cycled for a preset number of times, the reagent kit needs to be replaced, and the steps further include: S01: the rotary cutting valve is switched to the detection flow channel, the first pump is started, and the water in the clean water collection chamber is pushed into the common flow channel, the transfer channel and the detection flow channel in sequence; S02: the rotary cutting valve is switched to the air flow channel, the second pump or the first pump is started, and absorbs air into the transfer channel; S03: the rotary cutting valve is switched to the washing flow channel, the second pump is started, and a quantitative washing liquid is sucked into the transfer channel; S04: the rotary cutting valve switches to the detection channel again, the second pump is reset and pushes the washing liquid in the transfer channel into the detection channel and mixes the water in the detection channel into a diluted washing liquid, then the first pump is started and draws the diluted washing liquid in the detection channel into the transfer channel; S05: the rotary cutting valve switches to one of the reagent flow channels, the first pump starts, and pushes the diluted washing solution in the transfer channel into the reagent flow channel and the reagent chamber; the rotary cutting valve switches multiple reagent flow channels in sequence, the first pump starts, and pushes the diluted washing solution in the transfer channel into multiple reagent chambers in sequence; S06: the rotary cutting valve switches to the plurality of reagent flow channels in sequence, the first pump starts, and pushes the clean water in the common flow channel into the plurality of reagent flow channels and the plurality of reagent chambers in sequence; S07: Replace the reagent kit with a new one.

16. The control method of the urine tester according to claim 15, characterized in that: The rotary cutting valve is provided with a mixing chamber, and the mixing chamber is located on the path of the detection flow channel and is connected with the detection flow channel; Step S01: the rotary cutting valve is switched to the detection flow channel, the first pump is started, and the water in the clean water collection chamber is pushed into the common flow channel, the transfer channel and the mixing chamber in sequence; Step S04: the rotary cutting valve switches to the detection channel again, the second pump is reset and pushes the washing liquid in the transfer channel into the detection channel and then into the mixing chamber, the first pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid, and then the first pump starts to draw the diluted washing liquid in the detection channel into the transfer channel.

17. The control method of the urine tester according to claim 2, characterized in that: The rotary cutting valve is also provided with a washing flow channel; The urine test instrument also includes a washing liquid and a washing chamber containing the washing liquid; After the steps S1 to S9 are cycled for a preset number of times, the urine test instrument is cleaned regularly, including the steps of: S001: the rotary cutting valve is switched to the detection flow channel, the first pump is started, and the water in the clean water collection chamber is pushed into the common flow channel, the transfer channel and the detection flow channel in sequence; S002: the rotary cutting valve is switched to the air flow channel, the second pump or the first pump is started, and absorbs air into the transfer channel; S003: the rotary cutting valve is switched to the washing flow channel, the second pump is started, and a quantitative washing liquid is sucked into the transfer channel; S004: the rotary cutting valve switches to the detection flow channel again, the second pump is reset and pushes the washing liquid in the transfer channel into the detection flow channel and mixes the water in the detection flow channel into a diluted washing liquid; S005: The first pump is started to pump the diluted washing liquid in the detection channel into the transfer channel; The rotary cutting valve is switched to the lower sample flow channel, the first pump is started, and the dilution washing solution in the transfer channel is pushed into the sample collection chamber; S006: repeating steps S001 to S004, the first pump is started, and the diluted washing liquid in the detection channel is pushed into the detection cavity; S007: After waiting for a preset time, the rotary cutting valve is first switched to the lower sample flow channel, the first pump is started, and the water in the common flow channel is pushed into the sample collection cavity and then discharged, and then the rotary cutting valve is switched to the detection flow channel, the first pump is started, and the water in the common flow channel is pushed into the detection cavity and then discharged; or After waiting for a preset time, the rotary cutting valve switches to the detection flow channel, the first pump starts, and pushes the water in the common flow channel into the detection cavity and then discharges it. Then, the rotary cutting valve switches to the lower sample flow channel, the first pump starts, and pushes the water in the common flow channel into the sample collection cavity and then discharges it.

18. The control method of the urine tester according to claim 17, characterized in that: The rotary cutting valve is provided with a mixing chamber, and the mixing chamber is located on the path of the detection flow channel and is connected with the detection flow channel; Step S001: the rotary cutting valve is switched to the detection flow channel, the first pump is started, and the water in the clean water collection chamber is pushed into the common flow channel, the transfer channel and the mixing chamber in sequence; Step S004: the rotary cutting valve switches to the detection channel again, the second pump is reset and pushes the washing liquid in the transfer channel into the mixing chamber, the first pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid, and then the first pump starts and draws the diluted washing liquid in the detection channel into the transfer channel.

19. The control method of the urine test instrument according to claim 2, characterized in that: The rotary cutting valve comprises: A microfluidic chip, wherein the microfluidic chip is provided with the common flow channel, the lower sample flow channel, the upper sample flow channel, a plurality of the reagent flow channels, the detection flow channel, and the air flow channel; and A rotor is rotatably connected to the microfluidic chip and is provided with the transfer channel, the inner end of the transfer channel is connected to the common flow channel, and the outer end rotates with the rotor and is connected to the lower sample flow channel, the upper sample flow channel, a plurality of the reagent flow channels, the detection flow channel and the air flow channel.

20. The control method of the urine testing instrument according to claim 19, characterized in that: The microfluidic chip comprises: The flow channel plate has the following features on its front side: a central hole, the central hole penetrating the flow channel plate and communicating with the inner end of the common flow channel; and a plurality of circumferential holes, the plurality of circumferential holes being arranged around the central hole; and A cover plate, the cover plate being stacked between the front side of the flow channel plate and the rear side of the reagent box; The lower sample flow channel, the upper sample flow channel, the plurality of reagent flow channels, the detection flow channel, and the air flow channel are respectively connected to the plurality of circumferential holes.

21. The control method of the urine testing instrument according to claim 19, characterized in that: The urine tester also includes a housing, The housing comprises a detachable first shell and a detachable second shell; The detection mechanism comprises a detection plate, and the detection plate is provided with the detection cavity; The test kit, the microfluidic chip, and the detection board are located in the first housing; The first pump, the second pump, the rotor, and the detector are located in the second housing.

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