Closestool, urinalysis instrument and control method of urinalysis instrument

Abstract

The invention discloses a closestool, a urinalysis instrument and a control method thereof.The control method comprises the steps that S1, a water inlet three-way valve and an air inlet three-way valve are opened, a rotary-cut valve is switched to a sample flow channel, and a pump sucks a sample in a collection cavity into a transfer flow channel; s2, switching the rotary cutting valve to the reagent flow channel, and sucking the reagent in the reagent cavity into the transfer flow channel by the pump; s3, switching the rotary-cut valve to the detection flow channel, pushing the sample and the reagent in the transfer flow channel into the detection flow channel by the pump, and enabling the sample and the reagent to flow into the detection cavity; s4, the detector is used for detecting the sample in the detection flow channel; s5, after detection is finished, the water inlet three-way valve is closed, the pump sucks clear water into the water inlet three-way valve, then the water inlet three-way valve is opened, and the pump pushes the clear water in the water inlet three-way valve into the detection flow channel and the detection cavity and discharges the clear water from the detection cavity.

Description

Technical Field

[0001] The present invention relates to the technical field of urine testing instruments, and in particular to a toilet, a urine testing instrument and a control method thereof. Background Art

[0002] As human life expectancy increases, the importance of health care and maintenance has received more and more attention. Urine can reflect a person's health status to a certain extent. Quantitative analysis of urine components can help us understand diseases such as the pancreas and kidneys. Urinalysis is an important indicator for detecting a person's physical condition. It can usually detect pH, protein, occult blood, specific gravity, glucose, ketone bodies, urobilinogen, nitrates, white blood cells, bilirubin and vitamin C, reflecting a series of indicators of the body. Urine tests are usually conducted in hospitals. Due to the shortage of medical resources, the examinees often have to queue up to register, see a doctor, pay fees, collect urine, wait for batches of urine tests, and then queue up to get the results, which is time-consuming and laborious.

[0003] At present, urine testers for home use have appeared on the market. Urine testers for home use have realized functions such as flushing and urine collection. Usually, multiple pipelines and complicated flushing processes are set up. The toilet and the pipelines inside the toilet are difficult to clean, which can easily cause contamination to the urine sample that needs to be tested. Summary of the invention

[0004] The object of the present invention is to provide a toilet, a urine tester and a control method thereof to solve the problems of the prior art.

[0005] In order to solve the above technical problems, an embodiment of the present invention provides a urine test instrument, comprising: The rotary cutting valve comprises: A microfluidic chip, wherein the microfluidic chip is provided with a common flow channel, a plurality of reagent flow channels, a sample flow channel and a detection flow channel; A rotor, the rotor is rotatably connected to the microfluidic chip and is provided with a transfer channel, one end of the transfer channel is connected to the common channel, and the other end can rotate with the rotor and is connected to one of the plurality of reagent channels, the sample channel and the detection channel; A reagent kit, wherein the reagent kit is provided with a plurality of reagent chambers communicating with the plurality of reagent flow channels; A sampler, wherein the sampler is provided with a collection chamber, and the collection chamber is communicated with the outer end of the sample flow channel; A detection component, wherein the detection component is provided with a detector and a detection cavity, and the detection cavity is communicated with the detection flow channel; Pumps; a first pipeline, one end of which is in communication with the common flow channel; Second pipeline; a third pipeline, one end of which is connected to the pump; Water inlet pipe; Air intake duct; a water inlet three-way valve, the water inlet three-way valve being connected to the other end of the first pipeline, the water inlet pipeline and one end of the second pipeline respectively; and An air intake three-way valve is connected to the other end of the second pipeline, the other end of the third pipeline and the air intake pipeline respectively.

[0006] In one embodiment, the microfluidic chip includes a flow channel plate, and the flow channel plate is provided with: A central flow channel, wherein the central flow channel is formed by the bottom surface of the flow channel plate being recessed toward the top by a preset depth and is connected to the inner end of the common flow channel; A sample hole, a detection hole and a plurality of reagent holes, wherein the sample hole, the detection hole and the plurality of reagent holes are arranged at intervals around the central flow channel, the plurality of reagent holes penetrate the flow channel plate and are respectively connected to the inner ends of the plurality of reagent flow channels, and the outer ends of the plurality of reagent flow channels are connected to the plurality of reagent chambers; The sample hole is in communication with the inner end of the sample flow channel; The detection hole is communicated with the inner end of the detection flow channel.

[0007] In one embodiment, the rotary cutting valve further comprises: A first sealing gasket, which is stacked on the bottom surface of the flow channel plate and is provided with a first central hole and a plurality of first sealing holes, wherein the first central hole is connected to the central flow channel, and the plurality of first sealing holes are respectively aligned with and connected to the sample hole, the detection hole, and the plurality of reagent holes; and A first support plate, wherein the first support plate is located between the first sealing gasket and the rotor and is provided with a second center hole and a plurality of first circumferential holes, wherein the second center hole is connected with the first center hole and the inner end of the transfer channel; and the plurality of first circumferential holes are respectively aligned with and connected with the plurality of first sealing holes.

[0008] In one embodiment, the microfluidic chip further comprises: A second sealing gasket, which is stacked on the top surface of the flow channel plate and is provided with a plurality of second sealing holes, wherein the plurality of second sealing holes are respectively aligned with and communicated with the outer ends of the plurality of reagent flow channels; and A second support plate, the second support plate is located on the top surface of the plurality of second sealing pads and is provided with a plurality of second circumferential holes, the plurality of second circumferential holes are respectively aligned with and communicated with the plurality of second sealing holes; The plurality of reagent chambers are respectively communicated with the plurality of second circumferential holes.

[0009] In one embodiment, the reagent box is detachably connected to the second support plate.

[0010] In one embodiment, a plurality of threaded holes are further provided on the top surface of the second support plate, and the plurality of threaded holes are respectively connected to the plurality of second circumferential holes; The urine test instrument further comprises a plurality of insertion pins, the bottom ends of which are respectively located in the plurality of threaded holes and are threadedly connected to the second support plate; The bottom ends of the plurality of insertion pins are respectively connected with the plurality of the second circumferential holes, and the top ends are provided with needle tips, which can be inserted into the plurality of the reagent chambers.

[0011] In one embodiment, the urine testing instrument further comprises: A connecting plate, the connecting plate is located on the top surface of the second supporting plate and is provided with avoidance holes for avoiding the plurality of the pins; and A third sealing gasket is located on the top surface of the connecting plate and on the bottom surface of the reagent kit. The third sealing gasket is provided with a plurality of third sealing holes, and the plurality of third sealing holes are respectively interference-fitted with the plurality of pins.

[0012] In one embodiment, the plurality of reagent flow channels extend radially and have different lengths.

[0013] In one embodiment, outer ends of some of the reagent flow channels are on the same circumference, and outer ends of another part of the reagent flow channels are on another circumference.

[0014] In one embodiment, the urine test instrument further includes a leak-proof member, which is disposed in the reagent chamber and slidably disposed along the chamber wall of the reagent chamber to prevent the reagent from leaking out of the top opening of the reagent chamber; The leak-proof component has a through hole, and the through hole extends along the extension direction of the reagent chamber.

[0015] In one embodiment, a sealing film is sandwiched between the connecting plate and the third sealing gasket.

[0016] In one embodiment, the urine testing instrument further comprises a housing, wherein the flow channel plate, the reagent kit, the detection component, and the rotor are located in the housing; The top of the shell is provided with a mounting hole and a guide groove; The top end of the reagent box is located in the mounting hole and is provided with a positioning piece, and the positioning piece is located in the guide groove.

[0017] In one embodiment, a pull ring is provided at the top of the reagent box, and the pull ring is rotatably connected to the top of the reagent box.

[0018] In one embodiment, the detection component includes a detection plate and a detector, the detection plate is provided with the detection cavity and the mixing cavity which are connected to each other, the mixing cavity is connected to the detection flow channel and is used to mix the sample and the reagent, and the detection cavity is connected to the mixing cavity; The detection cavity detects the sample in the detection cavity.

[0019] In one embodiment, the urine test instrument further includes a sewage discharge pipe, one end of which is connected to the detection chamber and the other end of which is open to the housing; The detection component is provided with: a first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; and a second mixing bend, the second mixing bend being connected to the other end of the detection cavity; The present invention also relates to a toilet, comprising the above-mentioned urine tester, wherein the sampler is located on the inner wall of the toilet.

[0020] The present invention also relates to a control method of a urine tester, which uses the urine tester, comprising the steps of: S1: Open the water inlet three-way valve and the air inlet three-way valve, and switch the rotary cutting valve to the sample flow channel, so that the pump draws the sample in the collection chamber into the transfer flow channel; S2: Switch the rotary cutting valve to the reagent flow channel, and the pump draws the reagent in the reagent chamber into the transfer flow channel; S3: Switch the rotary cutting valve to the detection channel, and the pump pushes the sample and reagent in the transfer channel into the detection channel and into the detection chamber; S4: the detector detects the sample in the detection channel; S5: After the detection is completed, the water inlet three-way valve is closed, the pump draws clean water into the water inlet three-way valve, and then the water inlet three-way valve is opened, and the pump pushes the clean water in the water inlet three-way valve into the detection flow channel and the detection chamber, and discharges it from the detection chamber.

[0021] In one embodiment, before step S2, it is also necessary to determine the amount of extracted reagents, and according to the amount of extracted reagents, step S2 is repeated, each time the rotary cutting valve switches to a different reagent channel, and a different reagent is extracted into the transfer channel.

[0022] In one embodiment, the detection component is provided with: a first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; and a second mixing bend, the second mixing bend being connected to the other end of the detection cavity; Step S3 includes: S31: Switch the rotary cutting valve to the detection flow channel, close the air intake three-way valve, and the pump draws air into the third pipeline. Then, open the air intake three-way valve, and the pump pushes the sample and reagent in the transfer flow channel into the detection flow channel, and enters the first mixing bend from the detection flow channel, and then enters the detection chamber from the first mixing bend; S32: the pump rotates forward for a preset time and then reverses for a preset time, so that the sample and reagent in the detection chamber reciprocate in the first mixing curve, the detection chamber and the second mixing curve, and finally stay in the detection chamber.

[0023] In one embodiment, step S5 is followed by step S6: switching the rotary cutting valve to the sample flow channel, and closing the water inlet three-way valve, the pump draws clean water into the water inlet three-way valve, and then closes the water inlet three-way valve, and the pump pushes the clean water in the water inlet three-way valve into the first pipe. After repeating this for multiple times, the air inlet three-way valve is closed, the pump draws air into the third pipe, and then the air inlet three-way valve and the water inlet three-way valve are opened, and the pump pushes the water in the first pipe into the sample flow channel and the collection chamber, and discharges it.

[0024] In one embodiment, step S5 is followed by step S6: switching the rotary cutting valve to the detection flow channel, and closing the water inlet three-way valve, the pump draws clean water into the water inlet three-way valve, and then closes the water inlet three-way valve, and the pump pushes the clean water in the water inlet three-way valve into the first pipe. After repeating this for multiple times, the air inlet three-way valve is closed, the pump draws air into the third pipe, and then the air inlet three-way valve and the water inlet three-way valve are opened, and the pump pushes the water in the first pipe into the detection flow channel, and the water flows into the detection cavity from the detection flow channel and is then discharged.

[0025] In one embodiment, the step S1 further includes the following steps: The air inlet three-way valve is opened, and the water inlet three-way valve is closed, and the pump draws clean water into the water inlet pipe; Then, the water inlet three-way valve is opened, and the rotary cutting valve is switched to the sample flow channel; The air inlet three-way valve is opened, and the pump draws the sample in the collection chamber into the transfer flow channel; Switch the rotary cutting valve to the detection flow channel, close the water inlet three-way valve, open the air inlet three-way valve, and the pump draws the water from the water inlet pipe into the second pipe. Then open the water inlet three-way valve, and the pump draws the water from the second pipe and the sample from the transfer flow channel from the detection flow channel into the detection cavity and discharges them from the detection cavity.

[0026] In one embodiment, step S6 also includes step S7: resetting the rotary cutting valve, closing the air inlet three-way valve and the water inlet three-way valve, the pump sucking air, then opening the air inlet three-way valve, resetting the pump, and closing the water inlet three-way valve, thereby discharging the remaining water in the water inlet pipe from the water inlet pipe.

[0027] In one embodiment, after step S6, if the detection result is abnormal, the control module restarts steps S1 to S6; if the detection result is normal, the next detection item is performed.

[0028] In one embodiment, the urine test instrument further includes a warning light, and the warning light is connected to the control module; After step S6, if the detection results are abnormal for two consecutive times, the control module controls the warning light to send out a warning signal.

[0029] In one embodiment, the microfluidic chip is further provided with a washing channel; The urine test instrument also includes a washing liquid and a washing chamber containing the washing liquid; After the steps S1 to S5 are cycled for a preset number of times, the reagent kit needs to be replaced, and the control method further comprises the steps of: S01: Open the air inlet three-way valve and close the water inlet three-way valve, so that the pump draws clean water into the water inlet pipe, and then close the water inlet three-way valve, so that the pump quantitatively draws water from the water inlet pipe into the second pipe; S02: opening the water inlet three-way valve, and switching the rotary cut valve to the detection flow channel, and the pump pushes the water in the second pipeline into the detection flow channel; S03: switching the rotary cutting valve to the washing channel, and the pump sucking the washing liquid into the transfer channel; S04: the rotary cutting valve is switched to the detection flow channel, and the pump pushes the washing liquid in the transfer flow channel into the detection flow channel and mixes it with the water in the detection flow channel to form a diluted washing liquid; S05: the pump draws the diluted washing liquid in the detection channel back to the transfer channel; S06: switching the rotary cutting valve to a plurality of reagent flow channels in sequence, and after each switching, the pump pushes the dilution washing solution in the transfer flow channel into the reagent flow channel and into the reagent chamber; S07: closing the water inlet three-way valve, and the pump sucks the water from the second pipeline into the second pipeline; then opening the water inlet three-way valve, and the pump pushes the water from the second pipeline into the transfer channel; S08: The rotary cutting valve is switched to a plurality of reagent flow channels in sequence, and after each switching, the pump pushes the water in the transfer flow channel into the reagent flow channel and into the reagent chamber.

[0030] In one embodiment, the detection component further comprises: a first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; and a second mixing bend, the second mixing bend being connected to the other end of the detection cavity; Wherein, the control method comprises the steps of: S02: Open the water inlet three-way valve, and switch the rotary cutting valve to the detection flow channel, so that the pump pushes the water from the second pipeline into the detection flow channel, and then enters the detection cavity after entering the first mixing bend from the detection flow channel; S04: the pump pushes the washing liquid in the transfer channel into the detection channel and then into the detection chamber, and then the pump rotates forward for a preset time and then reverses for a preset time, so that the clean water and washing liquid in the detection chamber reciprocate in the first mixing bend, the detection chamber and the second mixing bend, and are mixed into a diluted washing liquid; S05: The pump sucks the diluted washing liquid in the detection chamber into the detection channel and then draws it back into the transfer channel.

[0031] In one embodiment, after step 08, step 09 is further included: switching the rotary cutting valve to the detection flow channel, and closing the water inlet three-way valve, the pump sucks the water from the water inlet pipe into the second pipe, and then opens the water inlet three-way valve, and resets the pump; The air inlet three-way valve is closed, the pump draws air into the third pipe, and then the air inlet three-way valve is opened, and the pump is reset. After repeating this process for multiple times, sufficient air is drawn into the transfer flow channel and the detection flow channel to discharge the remaining water from the detection flow channel.

[0032] In one embodiment, the microfluidic chip is further provided with a washing channel; The urine test instrument also includes a washing liquid and a washing chamber containing the washing liquid; After the steps S1 to S5 are cycled for a preset number of times, scheduled maintenance is required. The control method further includes the steps of: S001: Open the air inlet three-way valve and close the water inlet three-way valve, and the pump draws clean water into the water inlet pipe; S002: the pump draws a fixed amount of water from the water inlet pipe into the second pipe, opens the water inlet three-way valve, switches the rotary cut valve to the detection flow channel, and the pump pushes the water in the second pipe into the detection flow channel; S003: Switch the rotary cutting valve to the washing channel, and the pump draws the washing liquid in the washing chamber into the transfer channel; S004: Switch the rotary cutting valve to the detection flow channel, and the pump pushes the washing liquid in the transfer flow channel into the detection flow channel and mixes it with the water in the detection flow channel to dilute it into a diluted washing liquid; S005: the pump draws the diluted washing liquid in the detection channel back to the transfer channel; S006: Switch the rotary cutting valve to the sample flow channel, and the pump pushes the dilution washing solution in the transfer flow channel into the sample flow channel and the collection chamber; S007: repeating steps S002 to S004, the pump pushes the diluted washing liquid in the detection channel into the detection cavity; S008: After waiting for a preset time, the rotary cutting valve is switched to the sample flow channel; the water inlet three-way valve is closed, the pump draws the water from the water inlet pipe into the second pipe, and then the water inlet three-way valve is opened, the pump pushes the water from the second pipe into the sample flow channel, and discharges it from the collection chamber; S009: Switch the rotary cutting valve to the detection channel; close the water inlet three-way valve, and the pump draws the water from the water inlet pipe into the second pipe; then open the water inlet three-way valve, and the pump pushes the water from the second pipe into the detection channel and discharges it from the detection chamber.

[0033] In one embodiment, the detection component further comprises: a first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; and A second mixing bend, wherein two ends of the second mixing bend are respectively connected to one end of the sewage pipe and the other end of the detection chamber; In S002, the pump pumps a fixed amount of water in the water inlet pipe into the second pipe, opens the water inlet three-way valve, switches the rotary cut valve to the detection flow channel, and the pump pushes the water in the second pipe from the detection flow channel into the first mixing bend and then into the detection chamber; In S004, the pump pushes the washing liquid in the transfer channel into the detection channel and then into the detection chamber, and then the pump rotates forward for a preset time and then reverses for a preset time, so that the water and reagent in the detection chamber reciprocate in the first mixing bend, the detection chamber and the second mixing bend, and are mixed and diluted into diluted washing liquid; In S005, the pump draws the diluted washing liquid in the detection chamber into the detection channel, and then draws it back from the detection channel to the transfer channel.

[0034] The control method of the urine test instrument of the present invention can ensure that the internal pipelines are thoroughly cleaned, and can also perform regular maintenance to reduce pollution. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 It is a stereoscopic diagram of a urine testing instrument according to an embodiment of the present invention.

[0036] Figure 2 yes Figure 1 An exploded view of the urine testing instrument in the illustrated embodiment.

[0037] Figure 3 yes Figure 1 The assembly diagram of the embodiment shown is with the housing removed.

[0038] Figure 4 , Figure 5 and Figure 6 They are Figure 1 An exploded view of the embodiment shown in FIG. 1 after removing the housing, two three-way valves, the circuit board and the detection board.

[0039] Figure 7 , Figure 8 and Fig. 9 They are Figure 1 A three-dimensional view of the flow channel plate in the illustrated embodiment.

[0040] Fig.10 yes Fig. 9 A cross-sectional view of the flow channel plate along line AA in the illustrated embodiment.

[0041] Fig.11 yes Fig. 9 A cross-sectional view of the flow channel plate along line BB in the illustrated embodiment.

[0042] Fig.12 and Fig.13 They are Figure 1 A perspective view of the first sealing gasket in the illustrated embodiment.

[0043] Fig.14 and Fig.15 They are Figure 1 A perspective view of the second sealing gasket in the illustrated embodiment.

[0044] Fig.16 yes Figure 1 An exploded view of the embodiment shown in FIG. 1 after removing the housing, two three-way valves, the circuit board and the detection board.

[0045] Fig.17 yes Figure 1 Exploded view of the reagent cartridge, mounting base and pull ring in the illustrated embodiment.

[0046] Fig.18 It is a three-dimensional diagram of a detection board according to an embodiment of the present invention.

[0047] Fig.19 yes Fig.18 A perspective view of a detection plate of the illustrated embodiment.

[0048] Fig. 20 yes Fig.19 A cross-sectional view of the detection plate along line CC in the illustrated embodiment.

[0049] Fig.21 and Fig. 22 It is an exploded view of a reagent kit and a rotary cutting valve according to another embodiment of the present invention.

[0050] Fig.23 yes Fig.21 An exploded view of the reagent box and the leak-proof member in the illustrated embodiment.

[0051] Fig.24 yes Fig.21 A perspective view of the second sealing gasket in the illustrated embodiment.

[0052] Fig.25 yes Fig.21 A three-dimensional view of the flow channel plate in the illustrated embodiment.

[0053] Fig.26 yes Fig.21 An assembly diagram of the second support plate, the metal ring and the pins in the illustrated embodiment.

[0054] Fig. 27 It is a flow chart of a control method of a urine testing instrument according to an embodiment of the present invention.

[0055] Fig.28 It is a working fluid flow diagram of a urine testing instrument according to an embodiment of the present invention. DETAILED DESCRIPTION

[0056] In order to make the purpose, technical scheme and advantages of the present invention clearer, the following will be described in detail with reference to the accompanying drawings. However, it will be appreciated by those skilled in the art that in the various embodiments of the present invention, many technical details are provided in order to enable the reader to better understand the present application. However, even without these technical details and various changes and modifications based on the following embodiments, the technical scheme claimed for protection in the claims of the present application can be implemented.

[0057] Unless the context requires otherwise, throughout the specification and claims, the word "comprise" and variations such as "include" and "have" should be construed in an open, inclusive sense, ie, should be interpreted as "including, but not limited to."

[0058] The following will be described in detail with reference to the accompanying drawings to provide a clearer understanding of the purpose, features and advantages of the present invention. It should be understood that the embodiments shown in the accompanying drawings are not intended to limit the scope of the present invention, but are only intended to illustrate the essential spirit of the technical solution of the present invention.

[0059] References throughout the specification to "one embodiment" or "an embodiment" indicate that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of "in one embodiment" or "in an embodiment" in various places throughout the specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any manner in one or more embodiments.

[0060] As used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the context clearly dictates otherwise. It should be noted that the term "or" is generally employed in its sense including "and / or" unless the context clearly dictates otherwise.

[0061] In the following description, in order to clearly show the structure and working mode of the present invention, many directional words will be used for description, but the words "front", "back", "left", "right", "outside", "inside", "outward", "inward", "up", "down", etc. should be understood as convenient terms and should not be understood as restrictive terms.

[0062] The present invention relates to a toilet and a urine tester 100 thereof, wherein the urine tester 100 comprises a bracket 9, a rotary cutting valve, a reagent kit 2, a sampler, a detection component 3, a pump 6, two three-way valves, a plurality of pipelines, a control module and a housing 8, wherein the reagent kit 2, the detection component 3, the pump 6, the two three-way valves, a plurality of pipelines and the control module are located in the housing 8. The rotary cutting valve comprises a microfluidic chip, a rotor 4 and a driving member 5, and the microfluidic chip comprises a flow channel plate 1, a second sealing pad 44 and a second support plate 45.

[0063] The housing 8 can be installed in a water tank of a toilet, which is generally a smart toilet. A storage box is divided in the water tank of the smart toilet, and the storage box can be used to store various electrical components. Of course, in other embodiments, the urine tester 100 of the present invention can also be adapted to an ordinary toilet, and can also be set outside the water tank, and the specific installation position of the urine tester 100 is not limited.

[0064] The sampler (not shown) is located on the inner wall of the toilet and is provided with a sample collection cavity for collecting samples. A sensor is generally provided in the sample collection cavity for sensing whether a sample is collected in the collection cavity. The sensor may be an infrared sensor or other liquid level sensor, etc., and the specific type of the sensor is not limited.

[0065] The urine testing instrument of the present invention also comprises a water storage container for storing clean water. The water storage container is provided with a clean water collecting chamber for collecting clean water. A sensor for sensing liquid level is also provided in the clean water collecting chamber.

[0066] The reagent box 2 is used to hold a variety of reagents, and the microfluidic chip is used to receive samples and reagents. The rotary cutting valve cooperates with the pump 6 to push the samples and reagents into the detection chamber 32 of the detection component 3. The detection component 3 includes a detector and a detection plate 31, wherein the detection plate 31 is made of a transparent material and is provided with a detection chamber 32, and the detection chamber 32 is used to receive the samples and reagents in the microfluidic chip. The detector is used to detect the samples in the detection plate 31. The control module is used to control the operation of the driving member 5 and the pump 6, and can also receive information from the sensors in the detection component 3 and the sample collection chamber or the clean water collection chamber.

[0067] In a specific embodiment, Figure 7-9 As shown, the flow channel plate 1 is in the shape of a pancake formed around a vertical axis and is provided with a central flow channel 11, a plurality of reagent wells 12, a sample well 14, a detection well 13, a common flow channel 111, a sample flow channel 141 and a detection flow channel 131, wherein the central flow channel 11 is located at the center of the flow channel plate 1 and is formed by the bottom surface of the flow channel plate 1 being recessed toward the top by a preset depth, and the central flow channel 11 extends in the vertical direction and does not penetrate the flow channel plate 1.

[0068] The plurality of reagent holes 12 are arranged at intervals along a circle formed with the central flow channel 11 as the center and penetrate the flow channel plate 1, that is, each reagent hole 12 is at the same distance from the central flow channel 11. As a preferred embodiment, the plurality of reagent holes 12 are evenly spaced around the vertical axis. The top end of each reagent hole 12 is used to receive the reagent in the reagent box 2, and the bottom end is used for the reagent to flow into the common flow channel 111.

[0069] The sample hole 14 is formed by a depression at the bottom end of the flow channel plate 1 and is also located on the above-mentioned circumference, that is, the distance between the sample hole 14 and the central flow channel 11 is the same as the distance between any reagent hole 12 and the central flow channel 11, and is open toward the bottom surface of the flow channel plate 1.

[0070] The detection hole 13 is also formed by the bottom depression of the flow channel plate 1 and is also located on the above-mentioned circumference, that is, the distance between the detection hole 13 and the central flow channel 11 is the same as the distance between the sample hole 14 or the reagent hole 12 and the central flow channel 11, and is also open to the bottom surface of the flow channel plate 1.

[0071] The inner end of the sample flow channel 141 is connected to the sample hole 14, and the outer end extends radially to the radial outer side of the flow channel plate 1. The sample flow channel 141 is a flow channel extending radially along the flow channel plate 1 and is located inside the flow channel plate 1. The outer end of the sample flow channel is connected to the sample collection chamber through a pipeline.

[0072] The detection flow channel 131 is the same as the sample flow channel 141, and is also a flow channel extending in the radial direction of the flow channel plate 1, with its inner end communicating with the detection hole 13, and its outer end extending radially to the radial outer side of the flow channel plate 1, and the outer end opening of the detection flow channel 131 is adjacent to the outer end opening of the sample flow channel 141. A pipeline of the detection flow channel is connected to the detection cavity.

[0073] The common flow channel 111 is also a flow channel extending in the radial direction of the flow channel plate 1, but its inner end is connected to the central flow channel 11, and its outer end is also located radially outside the flow channel plate 1. The outer end of the common flow channel 111 is located above the detection flow channel 131 and the sample flow channel 141. The outer end of the common flow channel 111 is connected to the pump 6 through a pipe. After the pump 6 is started, the air in the common flow channel 111 can be pumped out to form a negative pressure state, so as to draw the reagent and the sample into the common flow channel 111. The pump 6 can also pump air into the common flow channel 111 and drive the reagent or sample in the common flow channel 111 to flow into the detection chamber 32 through the air.

[0074] The rotor 4 is connected to the driving member 5, such as Figure 5 As shown, the driving member 5 is a motor, which is mounted on a bracket 9 .

[0075] The bracket 9 is installed in the housing 8 and has an annular mounting ring 91 at the top. The output shaft of the motor extends in the vertical direction and has its top located in the mounting ring 91 .

[0076] The rotor 4 is connected to the output shaft of the motor and is also located in the mounting ring 91, while the flow channel plate 1 is located on the top surface of the rotor 4 and is fixedly connected to the mounting ring 91 by screws. When the motor is started, the rotor can be driven to rotate relative to the flow channel plate 1.

[0077] The rotor 4 is located on the bottom surface of the flow channel plate 1 and is provided with a transfer flow channel 41. The rotor 4 and the flow channel plate 1 are concentrically arranged, and the inner end 411 of the transfer flow channel 41 is located at the center of the rotor 4 and is open toward the top surface of the rotor 4. The inner end 411 of the transfer flow channel 41 is aligned with and connected to the bottom end of the central flow channel 11. The outer end 412 of the transfer flow channel 41 is also open toward the top surface of the rotor 4, and the projection of its outer end in the vertical direction is located on the projection of the circumference of the plurality of reagent wells 12 in the vertical direction. That is, as the rotor 4 rotates, the outer end 412 of the transfer flow channel 41 can be aligned with and connected to the bottom end of any reagent well 12, sample well 14 or detection well 13.

[0078] exist Figure 5In the illustrated embodiment, the transfer flow channel 41 is formed by a depression in the top surface of the rotor 4. It should be understood that in other embodiments, the transfer flow channel 41 may also be a flow channel located inside the rotor 4, with the outer end 412 and the inner end 411 both being arranged to be open toward the top surface of the rotor 4, the inner end 411 being connected to the central flow channel 11, and the outer end 412 being used to be connected to the reagent hole 12, the sample hole 14 or the detection hole 13. The present invention does not limit the specific implementation manner of the transfer flow channel 41.

[0079] The inner end 411 of the transfer channel 41 is connected to the central channel 11 and the common channel 111, and when the outer end 412 of the transfer channel 41 is aligned with the reagent hole 12, the common channel 111, the reagent hole 12 and the reagent chamber 21 are connected, and the pump 6 can extract the air in the common channel 111 and the reagent hole 12 to form a negative pressure, so as to draw the reagent in the reagent chamber 21 into the common channel 111. Of course, when the outer end 412 of the transfer channel 41 is aligned with the sample hole 14, the sample in the sample collection chamber can also be drawn into the common channel 111 in the same way.

[0080] In order to increase the sealing performance between the rotor 4 and the flow channel plate 1, a first sealing gasket 42 and a first supporting plate 43 are further provided between the rotor 4 and the flow channel plate 1. Figure 5 , Figure 6 , Fig.12 and Fig.13 As shown, the first sealing gasket 42 is stacked on the bottom surface of the flow channel plate 1 and is provided with a first center hole 421 and a plurality of first sealing holes 422. The first center hole 421 is a channel penetrating the first sealing gasket 42 and the top end is aligned with and connected to the center flow channel 11, and the plurality of first sealing holes 422 are also through holes and are respectively aligned with and connected to the sample hole 14, the detection hole 13 and the plurality of reagent holes 12.

[0081] The first support plate 43 is located between the first sealing gasket 42 and the rotor 4 and is provided with a second central hole 431 and a plurality of first circumferential holes 432. The second central hole 431 is a through hole penetrating the first support plate 43, and the top end is connected to the first central hole 421, and the bottom end is connected to the inner end of the transfer channel 41 of the rotor 4. The plurality of first circumferential holes 432 are also through holes and are aligned and connected to the plurality of first sealing holes 422 one by one.

[0082] The inner end 411 of the transfer channel 41 is connected to the common channel 111 through the first center hole 421 and the second center hole 431 , and the outer end 412 is connected to multiple reagent holes 12 , detection holes 13 or sample holes 14 through multiple first circumferential holes 432 and multiple first sealing holes 422 .

[0083] In addition, in order to increase the sealing effect, the bottom surface of the first sealing pad 42 is provided with a plurality of first bottom sealing rings 424, and the top surface is provided with a plurality of first top sealing rings 423. The plurality of first bottom sealing rings 424 and the plurality of first top sealing rings 423 are respectively arranged around the first center hole 421 and the plurality of first sealing holes 422, that is, one of the first bottom sealing rings 424 and one of the first top sealing rings 423 are arranged around the first center hole 421, and the remaining first top sealing rings 423 and the first bottom sealing rings 424 are all arranged around the first sealing hole 422. The first top sealing ring 423 and the first bottom sealing ring 424 have the same shape and size, and their projections in the vertical direction also overlap. After the rotor 4 and the flow channel plate 1 are fixed, the plurality of first top sealing rings 423 and the plurality of first bottom sealing rings 424 are squeezed by the rotor 4 and the flow channel plate 1, so as to increase the sealing effect between the rotor 4 and the flow channel plate 1 and prevent the sample or reagent from overflowing from between the first center hole 421 and the first sealing hole 422.

[0084] Of course, in other embodiments, the first top sealing ring 423 or the first bottom sealing ring 424 may be provided separately as long as the sealing effect can be ensured.

[0085] As a preferred solution, the bottom surface of the flow channel plate 1 is provided with a cylindrical receiving groove 15, such as Figure 8 As shown, the depth of the receiving groove 15 is just enough to accommodate the first sealing gasket 42 and the first supporting plate 43 , and the first supporting plate 43 and the first sealing gasket 42 are fixedly connected to the top wall of the receiving groove 15 by screws.

[0086] Furthermore, the side wall of the receiving groove 15 is further provided with a limiting groove 16 which is recessed toward the radial outside. Figure 6 and Figure 8 In the embodiment shown, there are four limit grooves 16, and the four limit grooves 16 are arranged at intervals. Four limit blocks located in the limit grooves 16 are respectively arranged on the radial outer sides of the first sealing gasket 42 and the first support plate 43, so as to limit the first support plate 43 and the first sealing gasket 42 from being driven by the rotor 4 to rotate.

[0087] The top surface of flow channel plate 1 is provided with multiple reagent flow channels 121, and the inner ends of multiple reagent flow channels 121 are respectively communicated with multiple reagent holes 12, and the outer ends diverge radially toward the outside. The outer end of reagent flow channel 121 is used to be communicated with reagent chamber 21, and the outer end of reagent flow channel 121 diverges radially toward the outside of flow channel plate 1, so that the outer ends of two adjacent reagent flow channels 121 are spaced apart from each other and increase, which is convenient to increase the radial dimension of each reagent chamber 21 and increase the reagent storage capacity. It should be understood that in other embodiments, one end of all reagent flow channels 121 needs to be on a circumference, communicated with reagent hole 12, and the other end can be located inside the circumference, or it can be arranged to diverge toward the outside of the circumference, or, in some embodiments, the top of reagent hole 12 is directly communicated with reagent chamber 21, and reagent flow channel 121 does not need to be arranged.

[0088] A second sealing gasket 44 is also stacked on the top surface of the flow channel plate 1. Figure 5 , Figure 6 , Fig.14 and Fig.15 As shown, the second support plate 45 is installed on the top surface of the second sealing gasket 44, and the second support plate 45 and the second sealing gasket 44 are both fixedly connected to the flow channel plate 1. Fig.14 and 15 In the illustrated embodiment, the second sealing gasket 44 and the second supporting plate 45 are fixed to the flow channel plate 1 by a plurality of screws.

[0089] The second sealing gasket 44 is located between the flow channel plate 1 and the second support plate 45 and is provided with a plurality of second sealing holes 441 . The plurality of second sealing holes 441 penetrate through the second sealing gasket 44 and are respectively aligned with and communicated with the outer ends of the plurality of reagent flow channels 121 .

[0090] The second support plate 45 is provided with a plurality of second circumferential holes 451 . The plurality of second circumferential holes 451 respectively penetrate the second support plate 45 and are respectively aligned with and communicated with the plurality of second sealing holes 441 .

[0091] The bottom surface of the second sealing pad 44 is provided with a plurality of second bottom sealing rings 443, and the top surface is provided with a plurality of second top sealing rings 442, wherein the second bottom sealing rings 443 and the second top sealing rings 442 are respectively annular and extend in the radial direction, and are respectively arranged around the second sealing hole 441. The plurality of second bottom sealing rings 443 and the plurality of second top sealing rings 442 have the same shape, and the projections of the plurality of second bottom sealing rings 443 and the plurality of second top sealing rings 442 in the vertical direction are respectively located outside the projections of the plurality of reagent flow channels 121 in the vertical direction, that is, the second bottom sealing rings 443 and the second top sealing rings 442 are used to prevent liquid from overflowing from the reagent flow channel 121.

[0092] In addition, in order to prevent the reagent from flowing radially in the second top sealing ring 442, a plurality of sealing rings 444 are further provided on the top surface of the second sealing gasket 44. The plurality of sealing rings 444 are respectively annular and extend around the plurality of second sealing holes 441, and the plurality of sealing rings 444 are located in the plurality of second top sealing rings 442. Each sealing ring 444 is divided into two parts along the circumferential direction, which are defined as an outer periphery and an inner periphery. The outer periphery is the part of the sealing ring 444 away from the center of the flow channel plate 1, and the inner periphery is the part close to the center. The outer periphery of each sealing ring 444 overlaps with the radial outer side of the second top sealing ring 442, and the inner periphery is located in the second top sealing ring 442.

[0093] The second sealing ring 444 is relatively small in shape to prevent the reagent from flowing radially in the second top sealing ring 442 .

[0094] The top surface of the second support plate 45 is also provided with a plurality of threaded holes 452, which are respectively connected to the plurality of second circumferential holes 451. A pin 46 is installed in each threaded hole 452, and the bottom end of the pin 46 is provided with a thread, which can be threadedly connected with the threaded hole 452. The top end is provided with a needle tip, which can be inserted into each reagent chamber 21.

[0095] The needle tip of each insertion needle 46 can be inserted into each reagent chamber 21 , with its top end communicating with the reagent chamber 21 , and its bottom end communicating with the outer end of the reagent flow channel 121 through the second circumferential hole 451 and the second sealing hole 441 .

[0096] The first sealing gasket and the second sealing gasket are both made of silicone or rubber, the second support plate 45 is made of plastic, and the flow channel plate 1 is made of stainless steel. In order to increase the sealing effect of the second sealing gasket and enhance the pressing force between the second support plate 45 and the flow channel plate 1, as a preferred solution, a concave ring 453 is provided on the top surface of the second support plate 45, and the concave ring 453 extends along the circumference of the second support plate 45 and is located at the edge of the second support plate 45. A metal ring 454 is installed in the concave ring 453, and the metal ring 454 is preferably made of stainless steel. The metal ring 454, the second support plate 45, and the second sealing gasket are fixed to the flow channel plate 1 by a plurality of screws. The metal ring 454 has a high hardness and can enhance the squeezing force on the second sealing gasket 44.

[0097] The plurality of pins 46 can be directly inserted into each reagent cavity 21 of the reagent box 2. However, as a preferred solution, a connecting plate 47 and another sealing gasket are provided between the second support plate 45 and the reagent box 2. The sealing gasket cooperates with the connecting plate 47 to increase the sealing performance between the second support plate 45 and the reagent box 2. The sealing gasket is defined as a third sealing gasket 48.

[0098] Specifically, the connecting plate 47 is annular and is provided with a plurality of avoidance holes 471, which are through holes penetrating the connecting plate 47. The plurality of pins 46 respectively pass through the plurality of avoidance holes 471 and are then inserted into the plurality of reagent chambers 21.

[0099] The third sealing pad 48 is also annular and has a plurality of third sealing holes 481. After the tops of the plurality of insertion pins 46 penetrate through the plurality of avoidance holes 471 and the plurality of third sealing holes 481, the needle tips thereof are respectively inserted into the plurality of reagent chambers 21. The tops of the plurality of insertion pins 46 and the plurality of third sealing holes 481 are interference-fitted to prevent the reagent in the reagent chamber 21 from leaking out from the insertion pins 46.

[0100] The inner diameter of the third sealing gasket 48 is larger than the inner diameter of the connecting plate 47 . The connecting plate 47 is connected to the bottom end of the reagent box 2 through a plurality of screws near the center, and squeezes the third sealing gasket 48 .

[0101] The connecting plate 47 , the third sealing gasket 48 and the reagent box 2 are fixedly assembled and can be removed from the housing 8 together.

[0102] The reagent kit 2 is cylindrical and is located on the top surface of the third sealing pad 48. The reagent kit 2 is provided with a plurality of reagent chambers 21 extending in the vertical direction, and the bottom end of the reagent chamber 21 is opened, and the needle tip of the insertion needle 46 can be inserted into the reagent chamber 21 from the opening.

[0103] The top wall of the housing 8 is provided with a circular mounting hole 81. Figure 2 As shown, after the reagent kit 2, connecting plate 47 and third sealing gasket 48 are assembled, they can be installed into the housing 8 through the mounting hole 81, and the needle tips of multiple pins 46 are inserted into multiple reagent chambers 21 through the avoidance hole 471 of the mounting plate and the third sealing hole 481 of the third sealing gasket 48.

[0104] A micro switch having a contact is also provided at the radial outer edge of the second support plate 45. The connecting plate 47 is also provided with a trigger block 24, such as Figure 4 As shown, the trigger block 24 is aligned with the contact point in the vertical direction. After the reagent box 2 and the connecting plate 47 are installed in the housing 8, the trigger block 24 on the connecting plate 47 will trigger the contact point. In other words, after the reagent box 2 is installed in place, the micro switch will be turned on.

[0105] The micro switch is signal-connected or electrically connected to the control module. When the contact of the micro switch is touched, a signal indicating that the reagent box 2 is installed in place is transmitted to the control module.

[0106] The inner wall of the mounting hole 81 is also provided with a guide groove 82, which is formed by the inner wall depression of the mounting hole 81. The radial outer side of the reagent box 2 is also provided with a positioning member 23 located in the guide groove 82, which is a long column and extends in the vertical direction of the reagent box 2.

[0107] When the reagent box 2 is installed, the positioning member 23 is matched with the guide groove 82 to facilitate the positioning and installation of the reagent box 2.

[0108] A pull ring 27 is provided at the top of the reagent box 2. Figure 1 , Fig.17 As shown, the pull ring 27 is annular and rotatably connected to the top of the reagent box 2. The pull ring 27 facilitates the removal of the reagent box 2 from the plurality of pins 46.

[0109] exist Fig.17 In the specific embodiment shown, a recessed installation groove 25 is provided on the top surface of the reagent box 2. The installation groove 25 may be a through groove extending in the vertical direction, or may be recessed in the vertical direction to a preset depth.

[0110] The mounting seat 22 is installed in the mounting groove 25. The mounting seat 22 is connected to the inner wall of the mounting groove 25 and is provided with a rotating shaft 26. The rotating shaft 26 is rotatably connected to the mounting seat 22. The pull ring 27 is annular and its two ends are respectively connected to the two ends of the rotating shaft 26. Of course, in other embodiments, the rotating shaft 26 can also be fixedly connected to the inner wall of the mounting groove 25, and the two ends of the pull ring 27 are respectively rotatably connected to the two ends of the rotating shaft 26.

[0111] Each reagent chamber of the reagent kit of the present invention is connected to the reagent flow channel of the rotary cutting valve. Through the rotation of a rotor, not only can a variety of reagents be driven into the flow channel plate, but also samples and clean water can be driven into the flow channel plate, which can not only complete the entire detection process, but also thoroughly clean the internal pipelines to improve the accuracy of the test. In addition, the reagent kit can hold more reagents, has a long use time, a large number of times, and requires less resources for detection. After the reagents in the reagent kit are used up, the reagent kit can be directly removed and replaced, and the operation method of replacing the reagent kit is simple.

[0112] The urine testing instrument 100 also includes a control module, which is connected to the micro switch, the driving member 5, the pump 6 and the detection component 3, and is used to receive signals from the micro switch and the detection component 3, and can also be used to control the operation of the driving member 5, the pump 6 and the detection component 3.

[0113] The pump 6 of the present invention is a plunger pump 6 , which is connected to the common flow channel 111 through a plurality of pipelines.

[0114] exist Fig.28 In the embodiment shown, the pump 6 is connected to the common flow channel 111 through three pipelines, namely the first pipeline 101, the second pipeline 102 and the third pipeline 103. Two three-way valves are arranged between the three pipelines, namely the water inlet three-way valve 71 and the air inlet three-way valve 72.

[0115] One end of the first pipeline 101 is connected to the common flow channel 111 , and one end of the third pipeline 103 is connected to the plunger pump 6 .

[0116] The water inlet three-way valve 71 is respectively connected to the other end of the first pipe 101, one end of the second pipe 102 and the water inlet pipe 104. The water inlet pipe 104 is used to receive water in the water tank to facilitate cleaning the flow channel and the detection cavity 32 in the flow channel plate 1.

[0117] The intake three-way valve 72 is respectively connected to the other end of the second pipeline 102, the other end of the third pipeline 103 and the intake pipeline 105. The intake pipeline 105 is used for exhausting or taking in air.

[0118] When it is necessary to extract a sample, the motor drives the rotor 4 to rotate so that the outer end of the transfer channel 41 is aligned with the sample hole 14, thereby connecting the common channel 111, the transfer channel 41 and the sample channel 141.

[0119] The air inlet three-way valve 72 and the water inlet three-way valve 71 are opened at the same time, so that the first pipeline 101, the second pipeline 102, and the third pipeline 103 are connected. At this time, the first pipeline 101, the second pipeline 102, the third pipeline 103, the common flow channel 111, the transfer flow channel 41, and the sample flow channel 141 are connected to each other. The pump 6 extracts the air in the common flow channel 111, the transfer flow channel 41, and the sample flow channel 141, and the common flow channel 111 and the sample flow channel 141 form a negative pressure, and the sample can enter the common flow channel 111 from the sample collection chamber.

[0120] When extracting the reagent, the rotor 4 is rotated and the rotary valve is switched so that the outer end of the transfer channel 41 is aligned with the reagent hole 12. The pump 6 draws the reagent in the reagent chamber 21 into the common channel 111.

[0121] The rotor 4 continues to rotate, so that the outer end of the transfer flow channel 41 is aligned with the detection hole 13. At this time, the common flow channel 111, the detection flow channel 131 and the detection cavity 32 are connected to each other.

[0122] Then close the air inlet three-way valve 72 and open the water inlet three-way valve 71 to draw the air in the air inlet pipe 105 into the third pipe 103. Then open the air inlet three-way valve 72 to connect the third pipe 103, the second pipe 102 and the first pipe 101, push the air into the common flow channel 111, and push the sample and reagent in the common flow channel 111 into the detection chamber 32.

[0123] The detection chamber 32 of the detection plate 31 is connected to the detection channel 131 through a pipeline, and the sample and reagent can flow from the common channel 111 into the detection channel 131 and the detection chamber 32 .

[0124] The outer shell 8 is also provided with a plurality of pipe holes 83 , which facilitate the air inlet pipe 105 , the water inlet pipe 104 , the pipe connected to the sample flow channel 141 , and the sewage discharge pipe to penetrate into the outer shell 8 .

[0125] As a preferred solution, a mixing chamber is further provided in the detection plate 31 , which is connected to the detection chamber 32 and has a width greater than that of the detection chamber 32 . The sample and reagent first enter the mixing chamber for mixing and then enter the detection chamber 32 for detection.

[0126] The mixing chamber 303 can be configured as a substantially circular chamber, or can be configured as a plurality of bends. Fig. 20 In the illustrated embodiment, the mixing chamber includes a first mixing bend 33 and a second mixing bend 34. The two ends of the first mixing bend 33 are respectively connected to the detection channel 131 and one end of the detection chamber 32, while the two ends of the second mixing bend 34 are respectively connected to one end of the sewage pipe and the other end of the detection chamber 32. The sewage pipe is connected to the second mixing bend 34, and the other end is located in the toilet.

[0127] The samples and reagents in the common flow channel 111 enter the detection chamber 32 from the first mixing bend 33, and then enter the second mixing bend 34. After staying for 1s-2s, the pump 6 operates in reverse to pump the samples and reagents in the second mixing bend 34 into the detection chamber 32. This process is repeated many times. The samples and reagents are repeatedly mixed in the first mixing bend 33, the detection chamber and the second mixing bend 34, and finally stay in the detection chamber 32 for detection.

[0128] After the detection, the pump 6 pushes the sample and reagent in the detection chamber 32 into the second mixing bend 34 in sequence and then into the sewage flow channel, and then enters the toilet from the sewage flow channel for discharge.

[0129] The present invention also relates to a control method of a urine test instrument 100, which is applied to the urine test instrument 100. Fig. 27 and Fig.28 As shown, the steps include: S1: Open the water inlet three-way valve 71 and the air inlet three-way valve 72, and switch the rotary cutting valve to the sample flow channel 141. The pump 6 rotates forward to suck the sample in the sample collection chamber into the transfer flow channel 41; When the water inlet three-way valve 71 is opened, the first pipeline 101 and the second pipeline 102 are connected; and when the air inlet three-way valve 72 is opened, the second pipeline 102 and the third pipeline 103 are connected.

[0130] S2: Switch the rotary cutting valve to the reagent flow channel 121, and the pump 6 rotates forward to absorb the reagent in the reagent chamber 21 into the transfer flow channel 41; S3: Switch the rotary cutting valve to the detection channel 131 , the pump 6 reverses and pushes the sample and reagent in the transfer channel 41 into the detection channel 131 and into the detection chamber 32 ; S4: the detector detects the sample in the detection channel 131; S5: After the detection is completed, the water inlet three-way valve 71 is closed, the pump 6 rotates forward to absorb clean water into the water inlet three-way valve 71, and then the water inlet three-way valve 71 is opened. The pump 6 is reset to push the clean water in the water inlet three-way valve 71 into the detection channel 131 and the detection chamber 32, and then discharged from the detection chamber 32.

[0131] In step S1 and step S2, samples and reagents are drawn into the transfer channel 41, respectively. After step S5, water is drawn from the water inlet pipe 104 into the transfer channel 41 and the detection chamber 32 for cleaning.

[0132] Optionally, before step S2, it is also necessary to determine the amount of extracted reagents, and repeat step S2 according to the amount of extracted reagents, each time the rotary cutting valve switches to a different reagent channel 121 to extract different reagents into the transfer channel 41.

[0133] As a preferred solution, a mixing chamber 303 is provided in the flow channel plate 1 . The mixing chamber 303 is located on the path of the detection flow channel 131 and is in communication with the detection flow channel 131 .

[0134] When the first mixing bend 33 and the second mixing bend 34 are provided in the detection plate 31, step S3 includes: S31: Switch the rotary cutting valve to the detection channel 131, reset the pump 6, close the air intake three-way valve 72, connect the third pipe and the air intake pipe 105, rotate the pump 6 forward to draw air into the third pipe, then open the air intake three-way valve 72, and reverse the pump 6 to push the sample and reagent in the transfer channel 41 into the detection channel 131, enter the first mixing bend 33 from the detection channel 131, and enter the detection chamber 32 from the first mixing bend 33; the plunger pump 6 is affected by the stroke and can draw external air from the air intake pipe into the transfer channel 41 multiple times to push the sample and reagent into the detection channel 131.

[0135] S32: the pump 6 rotates forward for a preset time and then reverses for a preset time, so that the sample and reagent in the detection chamber 32 reciprocate in the first mixing bend 33, the detection chamber 32 and the second mixing bend 34, and finally stays in the detection chamber 32.

[0136] Optionally, after step S5, step S6 is also included: switching the rotary cutting valve to the sample flow channel 141, and closing the water inlet three-way valve 71, the water inlet pipeline is connected to the second pipeline, the pump 6 rotates forward to absorb clean water into the water inlet three-way valve 71, and then closes the water inlet three-way valve 71, and the pump 6 resets to push the clean water in the water inlet three-way valve 71 into the first pipeline, after repeating multiple times, the air inlet three-way valve 72 is closed, the air inlet three-way valve 72 is connected to the third pipeline, the pump 6 rotates forward to absorb air into the third pipeline, and then opens the air inlet three-way valve 72 and the water inlet three-way valve 71, and the pump 6 reverses to push the water in the first pipeline into the sample flow channel 141 and the sample collection chamber, and discharges it. The plunger pump 6 needs to pump water into the first pipeline multiple times, and due to the stroke problem, it also needs to pump air into the third pipeline multiple times, and use air to push the water pumped into the first pipeline into the sample flow channel 141. The sample flows back to the sample collection chamber and is discharged from the sample collection chamber to clean the sample collection chamber.

[0137] Optionally, step S5 is followed by step S6: switching the rotary cutting valve to the detection channel 131, and closing the water inlet three-way valve 71, the pump 6 rotates forward to absorb clean water into the water inlet three-way valve 71, and then closes the water inlet three-way valve 71, and resets the pump 6 to push the clean water in the water inlet three-way valve 71 into the first pipe. After repeating this for many times, the air inlet three-way valve 72 is closed, the pump 6 rotates forward to absorb air into the third pipe, and then the air inlet three-way valve 72 and the water inlet three-way valve 71 are opened, the first pipe, the second pipe and the third pipe are connected, the pump 6 reverses the water in the first pipe and pushes it into the detection channel 131, which flows into the detection chamber 32 from the detection channel 131 and is then discharged. This step is a process for clearing the detection chamber 32.

[0138] Preferably, before step S1, the method further includes the following steps: opening the air inlet three-way valve 72 and closing the water inlet three-way valve 71, and rotating the pump 6 forward to suck clean water into the water inlet pipe; Then, the water inlet three-way valve 71 is opened, and the rotary cutting valve is switched to the sample flow channel 141; The air intake three-way valve 72 is opened, and the pump 6 rotates forward to absorb air. Then, the air intake three-way valve 72 is closed, and the pump 6 is reset to discharge air from the air intake pipe 105. Then, the air intake three-way valve 72 is opened, and the pump 6 absorbs air again until the sample in the sample collection chamber is sucked into the transfer flow channel 41. The pump 6 needs to evacuate air multiple times and exhaust air from the exhaust pipe to absorb the sample in the sample collection chamber into the transfer flow channel 41.

[0139] The rotary cutting valve is switched to the detection flow channel 131, and the water inlet three-way valve 71 is closed, the air inlet three-way valve 72 is opened, the pump 6 rotates forward to pump the water in the water inlet pipe into the second pipe, and then the water inlet three-way valve 71 is opened, and the pump 6 is reset.

[0140] The air inlet three-way valve 72 is closed, and the pump 6 rotates forward to suck air into the third pipe. The air inlet three-way valve 72 is closed, and the pump 6 is reset to push the air in the third pipe and the water in the second pipe into the transfer channel 41, and reverses to make the sample and water in the transfer channel 41 flow from the detection channel 131 into the detection chamber 32 and be discharged from the detection chamber 32. The sample is first drawn into the sample channel 141 and the transfer channel 41, and the sample in the transfer channel 41 is discharged from the detection chamber 32 with clean water, and part of the sample is retained in the sample channel 141 to facilitate the quantitative sample extraction in the following steps.

[0141] Furthermore, in general, it is necessary to test clean water as a reference first, so after the sample is drawn into the sample flow channel 141 and the clean water is drawn into the second pipe, it is necessary to close the water inlet three-way valve 71 to draw the water in the second pipe into the third pipe, and then switch the rotary valve to the detection flow channel 131, open the water inlet three-way valve 71 and the air inlet three-way valve 72, and push the water in the third pipe into the detection chamber 32 for detection. Of course, due to the stroke problem of the plunger pump 6, it is necessary to open the air inlet three-way valve 72 multiple times to draw external air into the transfer flow channel 41, first push the clean water into the detection chamber 32 for detection, and then test the sample.

[0142] Optionally, step S6 also includes step S7: resetting the rotary cutting valve, closing the air intake three-way valve 72 and the water intake three-way valve 71, connecting the third pipe to the air intake pipe, rotating the pump 6 forward to draw air from the air intake pipe into the third pipe, and then opening the air intake three-way valve 72, resetting the pump 6 to discharge the water in the water intake pipe in the reverse direction, and then closing the air intake three-way valve 72.

[0143] Optionally, after step S6, if the detection result is abnormal, the control module restarts steps S1 to S6; if the detection result is normal, the next detection item is performed.

[0144] Preferably, the urine test instrument 100 further includes a warning light. After step S6, if the detection results are abnormal for two consecutive times, the signal light will send out a warning signal.

[0145] The urine test instrument 100 also includes a sensing module or a fingerprint module, which is connected to the control module. After the sensing module senses the operator's corresponding action, it will send an instruction to the control module, or after the operator's fingerprint opens the fingerprint module, the fingerprint module will send an instruction to the control module, and the control module will then control the urine test instrument 100 to start.

[0146] Preferably, the microfluidic chip is further provided with a washing channel; the urine test instrument 100 further comprises a washing liquid and a washing chamber for containing the washing liquid; After the steps S1 to S5 are cycled for a preset number of times, the reagent kit 2 needs to be replaced, and the steps further include: S01: Open the air inlet three-way valve 72, close the water inlet three-way valve 71, rotate the pump 6 forward to suck clean water into the water inlet pipe, then close the water inlet three-way valve 71, and rotate the pump 6 forward to quantitatively extract water from the water inlet pipe 104 into the second pipe; S02: Open the water inlet three-way valve 71, and switch the rotary cut valve to the detection channel 131, and reset the pump 6 to push the water in the second pipeline into the detection channel 131; S03: Switch the rotary cutting valve to the washing channel, and the pump 6 rotates forward to suck the washing liquid into the transfer channel 41; S04: Switch the rotary cutting valve to the detection flow channel 131, and the pump 6 is reversed to push the washing liquid in the transfer flow channel 41 into the detection flow channel 131 and mix it with the water in the detection flow channel 131 to form a diluted washing liquid; S05: the pump 6 rotates forward to pump the diluted washing liquid in the detection channel 131 back to the transfer channel 41; S06: The rotary cutting valve is switched to a plurality of reagent flow channels 121 in sequence, and after each switching, the pump 6 is reversed to push the dilution washing solution in the transfer flow channel 41 into the reagent flow channel 121 and into the reagent chamber 21; S07: the water inlet three-way valve 71 is closed, the pump 6 rotates forward to suck the water in the second pipe into the second pipe, and then the water inlet three-way valve 71 is opened, and the pump 6 rotates reversely to push the water in the second pipe into the transfer channel 41; S08: The rotary cutting valve is switched to a plurality of reagent flow channels 121 in sequence, and after each switching, the pump 6 is reversed to push the water in the transfer flow channel 41 into the reagent flow channel 121 and into the reagent chamber 21 .

[0147] First dilute the water and washing liquid, then push them into multiple reagent flow channels 121 for washing and then flow into the reagent chamber 21, and then clean the reagent flow channels 121 with clean water and push them into the reagent chamber 21, that is, push the washing liquid and clean water into the old reagent chamber 2, and then disassemble the old reagent chamber 2 and replace it with a new reagent chamber 2.

[0148] Optionally, when the detection plate 31 is provided with a first mixing bend 33 and a second mixing bend 34, the clean water and the washing liquid can be fully mixed and diluted in the detection cavity 32 and the first mixing bend 33 and the second mixing bend 34, and the above steps S02, S04, and S05 are as follows: S02: Open the water inlet three-way valve 71, and switch the rotary cutting valve to the detection channel 131. The pump 6 is reset to push the water in the second pipeline into the detection channel 131, and then the water enters the first mixing bend 33 from the detection channel 131 and then enters the detection chamber 32; S04: the pump 6 is reversed to push the washing liquid in the transfer channel 41 into the detection channel 131 and then into the detection chamber 32. Then, the pump 6 is forward rotated for a preset time and then reversed for a preset time, so that the clean water and washing liquid in the detection chamber 32 flow back and forth in the first mixing bend 33, the detection chamber 32 and the second mixing bend 34, and are mixed into a diluted washing liquid. S05 : The pump 6 rotates forward to suck the diluted washing liquid in the detection chamber 32 into the detection channel 131 and then draws it back into the transfer channel 41 .

[0149] Preferably, after step 08, step 09 is further included: switching the rotary cutting valve to the detection flow channel 131, and closing the water inlet three-way valve 71, the pump 6 rotates forward to suck the water of the water inlet pipe into the second pipe, and then the water inlet three-way valve 71 is opened, and the pump 6 is reset; The air intake three-way valve 72 is closed, and the pump 6 rotates forward to inhale air into the third pipe. Then the air intake three-way valve 72 is opened, and the pump 6 is reset. After repeating this process for several times, sufficient air is drawn into the transfer channel 41 and the detection channel 131, and the remaining water is discharged from the detection channel 131.

[0150] If the diluted washing liquid in the detection channel 131 or the detection cavity 32 has not been used up, the remaining diluted washing liquid needs to be discharged from the detection channel 131. If it has been used up, the detection channel 131 can also be cleaned with water.

[0151] As a preferred solution, after steps S1 to S5 are cycled for a preset number of times, scheduled maintenance is required, and the steps further include: S001: Open the air inlet three-way valve 72, close the water inlet three-way valve 71, and rotate the pump 6 forward to suck clean water into the water inlet pipe; S002: the pump 6 rotates forward to pump a fixed amount of water in the water inlet pipe into the second pipe, the water inlet three-way valve 71 is opened, and the rotary cut valve is switched to the detection flow channel 131, and the pump 6 is reset to push the water in the second pipe into the detection flow channel 131; S003: Switch the rotary cutting valve to the washing channel, and the pump 6 rotates forward to pump the washing liquid in the washing chamber into the transfer channel 41; S004: Switch the rotary cutting valve to the detection channel 131, and the pump 6 is reversed to push the washing liquid in the transfer channel 41 into the detection channel 131 and mix it with the water in the detection channel 131 to dilute it into diluted washing liquid; S005: the pump 6 rotates forward to pump the diluted washing liquid in the detection channel 131 back to the transfer channel 41; S006: Switch the rotary cutting valve to the sample flow channel 141, and reset the pump 6 to push the dilution washing solution in the transfer flow channel 41 into the sample flow channel 141 and the sample collection chamber; S007: repeating steps S002 to S004, the pump 6 is reversed to push the diluted washing liquid in the detection channel 131 into the detection chamber 32; S008: After waiting for a preset time, the air intake three-way valve 72 is closed, and the pump 6 rotates forward to draw air into the third pipe, and then the air intake three-way valve 72 is opened. Due to the stroke problem of the plunger pump 6, it is necessary to draw air into the third pipe. Then the rotary cutting valve is switched to the sample flow channel 141; the water inlet three-way valve 71 is closed, and the pump 6 rotates forward to draw water from the water inlet pipe into the second pipe, and then the water inlet three-way valve 71 is opened, and the pump 6 is reset. The air intake three-way valve 72 is closed, and the pump 6 rotates forward to draw air into the third pipe, and then the air intake three-way valve 72 is opened, and part of the air is drawn into the third pipe to increase the driving stroke of the plunger pump 6, and then the pump 6 reverses to push the water through the second pipe into the sample flow channel 141 and discharge it from the sample collection chamber; S009: Switch the rotary cutting valve to the detection channel 131; close the water inlet three-way valve 71, rotate the pump 6 forward to draw the water from the water inlet pipe into the second pipe, then open the water inlet three-way valve 71, and reset the pump 6; close the air inlet three-way valve 72, rotate the pump 6 forward to draw air into the third pipe, then open the air inlet three-way valve 72, and reverse the pump 6 to push the water from the second pipe into the detection channel 131 and discharge it from the detection chamber 32.

[0152] If the detection plate 31 is provided with a first mixing bend 33 and a second mixing bend 34 , the first mixing bend 33 and the second mixing bend 34 can also be used to repeatedly dilute and mix the reagent and the clean water.

[0153] Specifically, in S002, the pump 6 rotates forward to pump the water in the water inlet pipe into the second pipe, opens the water inlet three-way valve 71, and switches the rotary cut valve to the detection channel 131. The pump 6 is reset to push the water in the second pipe from the detection channel 131 into the first mixing bend 33 and then into the detection chamber 32. In S004, the pump 6 is reversed to push the washing liquid in the transfer channel 41 into the detection channel 131 and then into the detection chamber 32, and then the pump 6 is forward rotated for a preset time, and then reversed for a preset time, so that the water and reagent in the detection chamber 32 reciprocate in the first mixing bend 33, the detection chamber 32 and the second mixing bend 34, and are mixed and diluted into diluted washing liquid; In S005 , the pump 6 rotates forward to pump the diluted washing liquid in the detection chamber 32 into the detection flow channel 131 , and then pumps the diluted washing liquid from the detection flow channel 131 back to the transfer flow channel 41 .

[0154] The urine tester of the present invention can accurately extract samples and reagents into the microfluidic chip through the cooperation of the rotary cutting valve, two three-way valves and the plunger pump, and the circuit structure is simple. A plunger pump can extract samples, clean water, reagents and air into the microfluidic chip, and can also cooperate with two three-way valves to complete the process of detecting flow channels, cleaning flow channels and regular maintenance. The flow channel plate of the microfluidic chip is disc-mounted, and more reagent flow channels can be set on it. The reagent box is installed on the top of the rotary cutting valve, and more reagent chambers can be set, and more reagents can be contained, thereby delaying the detection time.

[0155] The reagent kit and the microfluidic chip are detachably connected via pins, which eliminates the need for additional pipes, further reduces contamination issues, and facilitates disassembly and assembly of the reagent kit.

[0156] In another embodiment, the urine test instrument 100 also includes the above-mentioned rotary cutting valve, reagent kit 2, detection component 3 and plunger pump 6. The difference is that this embodiment does not need to set a three-way valve, but an air inlet hole and an air flow channel are set on the flow channel plate of the rotary cutting valve. The air inlet hole is located on the circumference formed by the multiple reagent holes and is formed by the bottom surface depression of the flow channel plate; the inner end of the air flow channel is connected to the air inlet hole, and the outer end is open to the outside of the flow channel plate, and the outer end is used to draw air into the rotary cutting valve. The implementation method of the air flow channel and the reagent flow channel is the same, and the transfer flow channel 41 can be switched with the rotary cutting valve and connected to the air flow channel.

[0157] In addition, in this embodiment, the common flow channel 111 is connected to the clean water collection chamber through a pipeline, and the pipeline includes a first section and a second section, the two ends of the first section are connected to the common flow channel 111 and the outlet of the pump 6, and the two ends of the second section are connected to the inlet of the pump 6 and the clean water collection chamber containing clean water. The first section is provided with a control valve, which is defined as the first valve. The second section is provided with another valve, which is defined as the second valve.

[0158] By controlling the first valve and the second valve, the water in the clean water collection chamber can flow into the common flow channel and clean each pipeline.

[0159] In addition, the urine tester 100 of the present invention can be applied to routine urine tests, such as 14 ascorbic acid tests, including vitamins (C, VC), white blood cells (WBC), urobilinogen (URO), bilirubin (BIL), occult blood (BLD), nitrite (NIT), pH, protein (PRO), urine specific gravity (SG), urine ketone bodies (KET), urine glucose (GLU), urine creatinine (CR), urine calcium (CA) and microalbumin (MA) + urine uric acid + UACR (urine microalbumin / creatinine ratio) + UPCR (urine protein / creatinine ratio) + urine uric acid comprehensive value (based on CKD-EPI algorithm). In order to be able to use more items for testing, a multi-ring reagent well group can also be set on the flow channel plate.

[0160] In one embodiment, Figure 22-Figure 26 As shown, the flow channel plate 1 is provided with a plurality of first reagent holes 122 and a plurality of second reagent holes 123 , and the plurality of first reagent holes 122 and the plurality of second reagent holes 123 are arranged at intervals around the middle flow channel and respectively penetrate the flow channel plate 1 .

[0161] The top surface of the flow channel plate 1 is provided with a first reagent flow channel 124 connected to the first reagent hole 122, and a second reagent flow channel 125 connected to the second reagent hole 123. The first reagent flow channel 124 and the second reagent flow channel 125 both extend radially, and the plurality of first reagent flow channels 124 and the plurality of second reagent flow channels 125 are at different diameters, so that the outer ends of the plurality of first reagent flow channels 124 and the outer ends of the plurality of second reagent flow channels 125 will not flow into the transfer flow channel 41 at the same time.

[0162] The outer ends of the plurality of first reagent flow channels 124 diverge radially outward to the edge of the flow channel plate 1, and the outer ends of the plurality of second reagent flow channels 125 also diverge radially outward. As a preferred embodiment, the plurality of first reagent holes 122 are evenly spaced along the circumferential direction, or the plurality of second reagent holes 123 are also evenly spaced along the circumferential direction. Alternatively, the plurality of first reagent holes 122 and the plurality of second reagent holes 123 are evenly spaced and arranged.

[0163] Preferably, the plurality of first reagent flow channels 124 and the plurality of second reagent flow channels 125 are also arranged at even intervals along the circumferential direction.

[0164] The outer ends of the first reagent flow channel 124 and the second reagent flow channel 125 are aligned with each reagent cavity of the reagent box 2, that is, the reagent box 2 is also provided with a plurality of first reagent cavities 211 and a second reagent cavity 212, the outer ends of the plurality of first reagent cavities 211 and the plurality of first reagent flow channels 124 are aligned one by one and connected, and the outer ends of the plurality of second reagent cavities 212 and the plurality of second reagent flow channels 125 are aligned one by one and connected. That is to say, the plurality of first reagent cavities 211 and the plurality of second reagent cavities 212 are also located on different circumferences.

[0165] In order to match the first reagent flow channel 124 and the second reagent flow channel 125, the second sealing hole 441 on the second sealing gasket needs to match the outer ends of the first reagent flow channel 124 and the second reagent flow channel 125, that is, part of the second sealing holes 441 are aligned with and connected to the outer ends of multiple first reagent flow channels 124, and another part of the second sealing holes 441 are aligned with and connected to the outer ends of multiple second reagent flow channels 125.

[0166] The second circumferential hole 451 on the second support plate 45, the positions of the plurality of pins 46, the avoidance hole 471 on the connecting plate 47 and the third sealing hole 481 of the third sealing pad 48 need to be arranged according to the position of the second sealing hole 441 and will not be described in detail.

[0167] In another embodiment, the plurality of first reagent holes 122 and the plurality of second reagent holes 123 are also arranged at intervals along the circumference formed with the central flow channel 11 as the center, and also penetrate the flow channel plate 1. However, the plurality of second reagent holes 123 and the plurality of first reagent holes 122 are located on different circumferences and on different diameters. The spacing between the plurality of second reagent holes 123 and the central flow channel 11 can be smaller or larger than the spacing between the plurality of first reagent holes 122 and the central flow channel 11.

[0168] The reagent kit 2 may also be provided with a plurality of first reagent chambers 211 and a plurality of second reagent chambers 212, wherein the plurality of first reagent chambers 211 and the plurality of first reagent holes 122 are respectively connected, and the plurality of second reagent chambers 212 and the plurality of second reagent holes 123 are respectively connected.

[0169] In addition, the top surface of the flow channel plate 1 may also be provided with a plurality of first reagent flow channels 124, the inner ends of the plurality of first reagent flow channels 124 are respectively connected to the plurality of first reagent holes 122, and the outer ends radially diverge to the edge of the flow channel plate 1. The inner ends are used for the plurality of first reagent holes 122, and the outer ends are used for communicating with the plurality of first reagent chambers 211.

[0170] Optionally, a plurality of second reagent flow channels 125 are provided on the top surface of the flow channel plate 1 , the inner ends of the plurality of second reagent flow channels 125 are respectively connected to the plurality of second reagent holes 123 , and the outer ends diverge toward the outside and are connected to the plurality of second reagent chambers 212 .

[0171] As a preferred solution, the plurality of first reagent holes 122 and the plurality of second reagent holes 123 are evenly spaced, so as to set the rotation angle of the rotor 4 according to the spacing between the plurality of reagent holes and control the rotation of the rotor 4. Of course, in some embodiments, the spacing between the plurality of first reagent holes 122 and the plurality of second reagent holes 123 can also be randomly set.

[0172] The transfer channel 41 on the rotor 4 is a channel formed by a depression on the top surface of the rotor 4. The outer end of the transfer channel 41 can be connected to multiple first reagent holes 122, and the middle part of the transfer channel 41 is also connected to any second reagent hole 123. With this design, more reagent chambers can be arranged in a limited space to detect more items.

[0173] A sealing film 28 is also provided between the connecting plate 47 and the third sealing pad 48. The sealing film 28 is not punctured before the reagent chamber is used, and the top opening of the reagent chamber is covered. After the reagent kit 2 is installed on the urine tester 100, the insertion pin 46 of the urine tester 100 punctures the sealing film 28 and is inserted into the reagent chamber. The sealing film 28 can be a plastic film or a thin film to prevent liquid from flowing out.

[0174] Preferably, the urine testing instrument 100 further includes: a leak-proof member 29 disposed in the reagent chamber, for preventing the reagent from leaking out from the top opening of the reagent chamber.

[0175] Furthermore, if Fig.23 As shown, the leak-proof member 29 has a through hole 291 , and the leak-proof member 29 is slidably arranged along the cavity wall of the reagent cavity, and the through hole 291 extends along the extension direction of the reagent cavity, that is, extends along the vertical direction.

[0176] There is also liquid sealing oil in the reagent chamber, and the liquid sealing oil is located at the top of the reagent for sealing the reagent. The leak-proof member 29 is inserted into the liquid sealing oil, and the aperture of the through hole 291 of the leak-proof member 29 is 4mm-5mm. Optionally, the aperture of the through hole 291 of the leak-proof member 29 is 4.5mm, 4.7mm or 4.8mm. When in use, the reagent is injected into the reagent chamber from the top entrance of the reagent chamber, and then the liquid sealing oil is injected, and the leak-proof member 29 is plugged into the liquid sealing oil, while ensuring the storage space in the reagent chamber, the inner diameter of the reagent chamber is reduced toward the top inlet area, so that when the urine test instrument 100 is transported and used, the reagent in the reagent chamber will not be shaken and leaked from the top opening. The outer diameter of the leak-proof member 29 is 0.5mm-2mm smaller than the inner diameter of the reagent chamber, and after the reagent is used, the leak-proof member 29 can drop with the liquid level.

[0177] Preferred embodiments of the present invention have been described above in detail, but it should be understood that aspects of the embodiments can be modified, if necessary, to employ aspects, features and concepts of the various patents, applications and publications to provide further embodiments.

[0178] These and other changes can be made to the embodiments in light of the above detailed description.In general, in the claims, the terms used should not be considered limited to the specific embodiments disclosed in the specification and the claims, but should be construed to include all possible embodiments along with the full scope of equivalents to which these claims are entitled.

[0179] Those skilled in the art will appreciate that the above-mentioned embodiments are specific examples for implementing the present invention, and in actual applications, various changes may be made thereto in form and detail without departing from the spirit and scope of the present invention.

Claims

1. A urine tester, characterized in that: include: The rotary cutting valve comprises: A microfluidic chip, wherein the microfluidic chip is provided with a common flow channel, a plurality of reagent flow channels, a sample flow channel and a detection flow channel; A rotor, the rotor is rotatably connected to the microfluidic chip and is provided with a transfer channel, one end of the transfer channel is connected to the common channel, and the other end can rotate with the rotor and is connected to one of the plurality of reagent channels, the sample channel and the detection channel; A reagent kit, wherein the reagent kit is provided with a plurality of reagent chambers communicating with the plurality of reagent flow channels; A sampler, wherein the sampler is provided with a collection chamber, and the collection chamber is communicated with the outer end of the sample flow channel; A detection component, wherein the detection component is provided with a detector and a detection cavity, and the detection cavity is communicated with the detection flow channel; Pumps; a first pipeline, one end of which is in communication with the common flow channel; Second pipeline; a third pipeline, one end of which is connected to the pump; Water inlet pipe; Air intake duct; a water inlet three-way valve, the water inlet three-way valve being connected to the other end of the first pipeline, the water inlet pipeline and one end of the second pipeline respectively; and An air intake three-way valve is connected to the other end of the second pipeline, the other end of the third pipeline and the air intake pipeline respectively.

2. The urine tester according to claim 1, characterized in that: The microfluidic chip comprises a flow channel plate, and the flow channel plate is provided with: A central flow channel, wherein the central flow channel is formed by the bottom surface of the flow channel plate being recessed toward the top by a preset depth and is connected to the inner end of the common flow channel; A sample hole, a detection hole and a plurality of reagent holes, wherein the sample hole, the detection hole and the plurality of reagent holes are arranged at intervals around the central flow channel, the plurality of reagent holes penetrate the flow channel plate and are respectively connected to the inner ends of the plurality of reagent flow channels, and the outer ends of the plurality of reagent flow channels are connected to the plurality of reagent chambers; The sample hole is in communication with the inner end of the sample flow channel; The detection hole is communicated with the inner end of the detection flow channel.

3. The urine tester according to claim 2, characterized in that: The rotary cutting valve also includes: A first sealing gasket, which is stacked on the bottom surface of the flow channel plate and is provided with a first central hole and a plurality of first sealing holes, wherein the first central hole is connected to the central flow channel, and the plurality of first sealing holes are respectively aligned with and connected to the sample hole, the detection hole, and the plurality of reagent holes; and A first support plate, wherein the first support plate is located between the first sealing gasket and the rotor and is provided with a second center hole and a plurality of first circumferential holes, wherein the second center hole is connected with the first center hole and the inner end of the transfer channel; and the plurality of first circumferential holes are respectively aligned with and connected with the plurality of first sealing holes.

4. The urine tester according to claim 3, characterized in that: The microfluidic chip also includes: A second sealing gasket, which is stacked on the top surface of the flow channel plate and is provided with a plurality of second sealing holes, wherein the plurality of second sealing holes are respectively aligned with and communicated with the outer ends of the plurality of reagent flow channels; and A second support plate, the second support plate is located on the top surface of the plurality of second sealing pads and is provided with a plurality of second circumferential holes, the plurality of second circumferential holes are respectively aligned with and communicated with the plurality of second sealing holes; The plurality of reagent chambers are respectively communicated with the plurality of second circumferential holes.

5. The urine tester according to claim 4, characterized in that: The reagent box is detachably connected to the second supporting plate.

6. The urine tester according to claim 5, characterized in that: The top surface of the second support plate is also provided with a plurality of threaded holes, and the plurality of threaded holes are respectively connected with the plurality of second circumferential holes; The urine test instrument further comprises a plurality of insertion pins, the bottom ends of which are respectively located in the plurality of threaded holes and are threadedly connected to the second support plate; The bottom ends of the plurality of insertion pins are respectively connected with the plurality of the second circumferential holes, and the top ends are provided with needle tips, which can be inserted into the plurality of the reagent chambers.

7. The urine tester according to claim 6, characterized in that: The urine tester also includes: A connecting plate, the connecting plate is located on the top surface of the second supporting plate and is provided with avoidance holes for avoiding the plurality of the pins; and A third sealing gasket is located on the top surface of the connecting plate and on the bottom surface of the reagent kit. The third sealing gasket is provided with a plurality of third sealing holes, and the plurality of third sealing holes are respectively interference-fitted with the plurality of pins.

8. The urine tester according to claim 3, characterized in that: The plurality of reagent flow channels extend radially and have different lengths.

9. The urine tester according to claim 8, characterized in that: The outer ends of some of the reagent flow channels are located on the same circumference, and the outer ends of another part of the reagent flow channels are located on another circumference.

10. The urine tester according to claim 8, characterized in that: The urine test instrument further includes a leak-proof member, which is disposed in the reagent chamber and slidably disposed along the chamber wall of the reagent chamber to prevent the reagent from leaking out of the top opening of the reagent chamber; The leak-proof component has a through hole, and the through hole extends along the extension direction of the reagent chamber.

11. The urine tester according to claim 7, characterized in that: A sealing film is sandwiched between the connecting plate and the third sealing gasket.

12. The urine tester according to claim 7, characterized in that: The urine test instrument further comprises a housing, wherein the flow channel plate, the reagent kit, the detection component and the rotor are located in the housing; The top of the shell is provided with a mounting hole and a guide groove; The top end of the reagent box is located in the mounting hole and is provided with a positioning piece, and the positioning piece is located in the guide groove.

13. The urine tester according to claim 8, characterized in that: A pull ring is provided at the top of the reagent box, and the pull ring is rotatably connected to the top of the reagent box.

14. The urine tester according to claim 8, characterized in that: The detection component comprises a detection plate and a detector, the detection plate is provided with the detection cavity and the mixing cavity which are communicated with each other, the mixing cavity is communicated with the detection flow channel and is used to mix the sample and the reagent, and the detection cavity is communicated with the mixing cavity; The detection cavity detects the sample in the detection cavity.

15. The urine tester according to claim 12, characterized in that: The urine test instrument further includes a sewage discharge pipe, one end of which is connected to the detection chamber and the other end of which is open to the housing; The detection component is provided with: a first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; and The second mixing bend has two ends which are respectively connected with one end of the sewage pipe and the other end of the detection chamber.

16. A toilet, characterized in that: The toilet includes the urine testing instrument according to claim 1, and the sampler is located on the inner wall of the toilet.

17. A method for controlling a urine tester, characterized in that: The urine tester according to claim 1 comprises the following steps: S1: Open the water inlet three-way valve and the air inlet three-way valve, and switch the rotary cutting valve to the sample flow channel, so that the pump draws the sample in the collection chamber into the transfer flow channel; S2: Switch the rotary cutting valve to the reagent flow channel, and the pump draws the reagent in the reagent chamber into the transfer flow channel; S3: Switch the rotary cutting valve to the detection channel, and the pump pushes the sample and reagent in the transfer channel into the detection channel and into the detection chamber; S4: the detector detects the sample in the detection channel; S5: After the detection is completed, the water inlet three-way valve is closed, the pump draws clean water into the water inlet three-way valve, and then the water inlet three-way valve is opened, and the pump pushes the clean water in the water inlet three-way valve into the detection flow channel and the detection chamber, and discharges it from the detection chamber.

18. The control method of the urine tester according to claim 17, characterized in that: Before step S2, it is also necessary to determine the amount of the extracted reagents, and repeat step S2 according to the amount of the extracted reagents, each time the rotary cutting valve switches to a different reagent flow channel, and a different reagent is extracted into the transfer flow channel.

19. The control method of the urine testing instrument according to claim 17, characterized in that: The detection component is provided with: A first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; as well as a second mixing bend, the second mixing bend being connected to the other end of the detection cavity; Step S3 includes: S31: Switch the rotary cutting valve to the detection flow channel, close the air intake three-way valve, and the pump draws air into the third pipeline. Then, open the air intake three-way valve, and the pump pushes the sample and reagent in the transfer flow channel into the detection flow channel, and enters the first mixing bend from the detection flow channel, and then enters the detection chamber from the first mixing bend; S32: the pump rotates forward for a preset time and then reverses for a preset time, so that the sample and reagent in the detection chamber reciprocate in the first mixing curve, the detection chamber and the second mixing curve, and finally stay in the detection chamber.

20. The control method of the urine testing instrument according to claim 17, characterized in that: Step S5 also includes step S6: switching the rotary cutting valve to the sample flow channel, and closing the water inlet three-way valve, the pump sucks clean water into the water inlet three-way valve, and then closing the water inlet three-way valve, the pump pushes the clean water in the water inlet three-way valve into the first pipe, after repeating multiple times, closing the air inlet three-way valve, the pump sucks air into the third pipe, and then opening the air inlet three-way valve and the water inlet three-way valve, the pump pushes the water in the first pipe into the sample flow channel and the collection chamber, and discharges it.

21. The control method of the urine testing instrument according to claim 17, characterized in that: Step S5 is followed by step S6: switching the rotary cutting valve to the detection flow channel, and closing the water inlet three-way valve, the pump sucks clean water into the water inlet three-way valve, and then closing the water inlet three-way valve, the pump pushes the clean water in the water inlet three-way valve into the first pipe, after repeating multiple times, closing the air inlet three-way valve, the pump sucks air into the third pipe, and then opening the air inlet three-way valve and the water inlet three-way valve, the pump pushes the water in the first pipe into the detection flow channel, and the water flows into the detection cavity from the detection flow channel and is then discharged.

22. The control method of the urine testing instrument according to claim 17, characterized in that: Before step S1, the method further includes the following steps: The air inlet three-way valve is opened, and the water inlet three-way valve is closed, and the pump draws clean water into the water inlet pipe; Then, the water inlet three-way valve is opened, and the rotary cutting valve is switched to the sample flow channel; The air inlet three-way valve is opened, and the pump draws the sample in the collection chamber into the transfer flow channel; Switch the rotary cutting valve to the detection flow channel, close the water inlet three-way valve, open the air inlet three-way valve, and the pump draws the water from the water inlet pipe into the second pipe. Then open the water inlet three-way valve, and the pump draws the water from the second pipe and the sample from the transfer flow channel from the detection flow channel into the detection cavity and discharges them from the detection cavity.

23. The control method of the urine testing instrument according to claim 22, characterized in that: Step S6 also includes step S7: resetting the rotary cutting valve, closing the air inlet three-way valve and the water inlet three-way valve, the pump sucking air, then opening the air inlet three-way valve, resetting the pump, and closing the water inlet three-way valve, thereby discharging the remaining water in the water inlet pipe from the water inlet pipe.

24. The control method of the urine test instrument according to claim 21, characterized in that: After step S6, if the detection result is abnormal, the control module restarts steps S1 to S6; if the detection result is normal, the next detection item is performed.

25. The control method of the urine test instrument according to claim 17, characterized in that: The urine test instrument also includes a warning light, which is connected to the control module; After step S6, if the detection results are abnormal for two consecutive times, the control module controls the warning light to send out a warning signal.

26. The control method of the urine testing instrument according to claim 17, characterized in that: The microfluidic chip is also provided with a washing channel; The urine test instrument also includes a washing liquid and a washing chamber containing the washing liquid; After the steps S1 to S5 are cycled for a preset number of times, the reagent kit needs to be replaced, and the control method further comprises the steps of: S01: Open the air inlet three-way valve and close the water inlet three-way valve, so that the pump draws clean water into the water inlet pipe, and then close the water inlet three-way valve, so that the pump quantitatively draws water from the water inlet pipe into the second pipe; S02: opening the water inlet three-way valve, and switching the rotary cut valve to the detection flow channel, and the pump pushes the water in the second pipeline into the detection flow channel; S03: switching the rotary cutting valve to the washing channel, and the pump sucking the washing liquid into the transfer channel; S04: the rotary cutting valve is switched to the detection flow channel, and the pump pushes the washing liquid in the transfer flow channel into the detection flow channel and mixes it with the water in the detection flow channel to form a diluted washing liquid; S05: the pump draws the diluted washing liquid in the detection channel back to the transfer channel; S06: switching the rotary cutting valve to a plurality of reagent flow channels in sequence, and after each switching, the pump pushes the dilution washing solution in the transfer flow channel into the reagent flow channel and into the reagent chamber; S07: closing the water inlet three-way valve, and the pump sucks the water from the second pipeline into the second pipeline; then opening the water inlet three-way valve, and the pump pushes the water from the second pipeline into the transfer channel; S08: The rotary cutting valve is switched to a plurality of reagent flow channels in sequence, and after each switching, the pump pushes the water in the transfer flow channel into the reagent flow channel and into the reagent chamber.

27. The control method of the urine testing instrument according to claim 26, characterized in that: The detection component also includes: a first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; and a second mixing bend, the second mixing bend being connected to the other end of the detection cavity; Wherein, the control method comprises the steps of: S02: Open the water inlet three-way valve, and switch the rotary cutting valve to the detection flow channel, so that the pump pushes the water from the second pipeline into the detection flow channel, and then enters the detection cavity after entering the first mixing bend from the detection flow channel; S04: the pump pushes the washing liquid in the transfer channel into the detection channel and then into the detection chamber, and then the pump rotates forward for a preset time and then reverses for a preset time, so that the clean water and washing liquid in the detection chamber reciprocate in the first mixing bend, the detection chamber and the second mixing bend, and are mixed into a diluted washing liquid; S05: The pump sucks the diluted washing liquid in the detection chamber into the detection channel and then draws it back into the transfer channel.

28. The control method of the urine testing instrument according to claim 26, characterized in that: Step 08 and step 09 are also included: switching the rotary cutting valve to the detection flow channel, closing the water inlet three-way valve, the pump sucking the water from the water inlet pipe into the second pipe, then opening the water inlet three-way valve, and resetting the pump; The air inlet three-way valve is closed, the pump draws air into the third pipe, and then the air inlet three-way valve is opened, and the pump is reset. After repeating this process for multiple times, sufficient air is drawn into the transfer flow channel and the detection flow channel to discharge the remaining water from the detection flow channel.

29. The control method of the urine testing instrument according to claim 17, characterized in that: The microfluidic chip is also provided with a washing channel; The urine test instrument also includes a washing liquid and a washing chamber containing the washing liquid; After the steps S1 to S5 are cycled for a preset number of times, scheduled maintenance is required. The control method further includes the steps of: S001: Open the air inlet three-way valve and close the water inlet three-way valve, and the pump draws clean water into the water inlet pipe; S002: the pump draws a fixed amount of water from the water inlet pipe into the second pipe, opens the water inlet three-way valve, switches the rotary cut valve to the detection flow channel, and the pump pushes the water in the second pipe into the detection flow channel; S003: Switch the rotary cutting valve to the washing channel, and the pump draws the washing liquid in the washing chamber into the transfer channel; S004: Switch the rotary cutting valve to the detection flow channel, and the pump pushes the washing liquid in the transfer flow channel into the detection flow channel and mixes it with the water in the detection flow channel to dilute it into a diluted washing liquid; S005: the pump draws the diluted washing liquid in the detection channel back to the transfer channel; S006: Switch the rotary cutting valve to the sample flow channel, and the pump pushes the dilution washing solution in the transfer flow channel into the sample flow channel and the collection chamber; S007: repeating steps S002 to S004, the pump pushes the diluted washing liquid in the detection channel into the detection cavity; S008: After waiting for a preset time, the rotary cutting valve is switched to the sample flow channel; the water inlet three-way valve is closed, the pump draws the water from the water inlet pipe into the second pipe, and then the water inlet three-way valve is opened, the pump pushes the water from the second pipe into the sample flow channel, and discharges it from the collection chamber; S009: Switch the rotary cutting valve to the detection channel; close the water inlet three-way valve, and the pump draws the water from the water inlet pipe into the second pipe; then open the water inlet three-way valve, and the pump pushes the water from the second pipe into the detection channel and discharges it from the detection chamber.

30. The control method of the urine testing instrument according to claim 29, characterized in that: The detection component also includes: a first mixing bend, wherein two ends of the first mixing bend are respectively connected to the detection flow channel and one end of the detection cavity; and a second mixing bend, the second mixing bend being connected to the other end of the detection cavity; In S002, the pump pumps a fixed amount of water in the water inlet pipe into the second pipe, opens the water inlet three-way valve, switches the rotary cut valve to the detection flow channel, and the pump pushes the water in the second pipe from the detection flow channel into the first mixing bend and then into the detection chamber; In S004, the pump pushes the washing liquid in the transfer channel into the detection channel and then into the detection chamber, and then the pump rotates forward for a preset time and then reverses for a preset time, so that the water and reagent in the detection chamber reciprocate in the first mixing bend, the detection chamber and the second mixing bend, and are mixed and diluted into diluted washing liquid; In S005, the pump draws the diluted washing liquid in the detection chamber into the detection channel, and then draws it back from the detection channel to the transfer channel.

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