Endoscope imaging system and light source host thereof

Abstract

The invention relates to an endoscope imaging system and a light source host thereof, the light source host is used for outputting imaging visible light for exciting a fluorescent dye and generating a visible light image, and the imaging visible light does not comprise visible light of a first wave band and comprises visible light of a second wave band and a third wave band; wherein the first wave band is at least partial wave band in an emission wave band interval of the fluorescent dye, the second wave band is at least partial wave band in an excitation wave band interval of the fluorescent dye, and the third wave band is different from the first wave band and the second wave band; the endoscope is used for transmitting imaging visible light to a target object, receiving reflected light and visible light fluorescence from the target object and generating a first electric signal; the camera host is used for separating the reflected light signal and the visible light fluorescence signal from the first electric signal, generating a visible light image based on the reflected light signal, and generating a visible light fluorescence image based on the visible light fluorescence signal. The system can ensure the imaging effect of reflected light imaging while performing visible light fluorescence imaging.

Description

Technical Field

[0001] The present invention relates to the field of medical equipment, and more particularly to an endoscopic imaging system and a light source host thereof. Background Art

[0002] Fluorescence endoscopic imaging systems have been widely used in minimally invasive surgery. They use exogenous fluorescent dyes to mark specific tumors, lymphatic and vascular basins, etc., which greatly improves the accuracy and efficiency of minimally invasive surgery. However, most of the current fluorescence endoscopic imaging systems only support fluorescence imaging in the near-infrared band such as indocyanine green (ICG), but have not been able to support and popularize visible light fluorescence imaging. One of the main reasons is that unlike near-infrared fluorescence imaging, visible light fluorescence and white light are in the same band, and it is basically difficult to achieve simultaneous white light wide-spectrum imaging and visible light fluorescence imaging. At present, most endoscopic imaging systems that support visible light fluorescence imaging need to sacrifice the color and brightness of the tissue in the non-fluorescent area image, and it is almost impossible to see the texture structure of the tissue surface. Doctors can only confirm the diagnosis results by frequently switching the lighting mode to obtain fluorescence and white light images respectively, which makes it difficult for visible light fluorescence to meet the needs of guiding doctors to perform surgical operations during surgery. Summary of the invention

[0003] A series of simplified concepts are introduced in the Summary of the Invention, which will be further described in detail in the Detailed Description of the Invention. The Summary of the Invention does not mean to attempt to define the key features and essential technical features of the claimed technical solution, nor does it mean to attempt to determine the scope of protection of the claimed technical solution.

[0004] A first aspect of an embodiment of the present invention provides an endoscope imaging system, including a light source host, an endoscope, a camera host and a display, wherein:

[0005] The light source host is used to output imaging visible light, and the imaging visible light is used to excite the fluorescent dye excited by the visible light and generate a reflected light image, and the imaging visible light does not include visible light in the first band, and includes visible light in the second band and visible light in the third band; wherein the first band is at least a part of the band within the emission band interval of the fluorescent dye, the second band is at least a part of the band within the excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band;

[0006] The endoscope is used to transmit the imaging visible light output by the light source host to the target object containing the fluorescent dye excited by the visible light, receive the reflected light and visible light fluorescence from the target object, and generate a first electrical signal;

[0007] The camera host is connected to the endoscope and is used to separate the reflected light signal and the visible light fluorescence signal from the first electrical signal, and the camera host generates a reflected light image based on the reflected light signal and generates a visible light fluorescence image based on the visible light fluorescence signal;

[0008] The display is used for displaying the reflected light image and / or the visible light fluorescent image.

[0009] In one embodiment, the light source host includes a visible light source and a first filter component, wherein the first filter component is used to filter out the imaging visible light of the first band in the imaging visible light output by the visible light source, and to transmit the imaging visible light of the second band and the imaging visible light of the third band.

[0010] In one embodiment, the light source host includes a first visible light source, a second visible light source and a first filter assembly, wherein the first filter assembly is used to filter out the imaging visible light of the first wavelength band output by the first visible light source and transmit the imaging visible light of the second wavelength band, and the second visible light source is used to output the imaging visible light of the third wavelength band;

[0011] Alternatively, the first filter assembly is used to filter out imaging visible light of the first band in the imaging visible light output by the first visible light light source, and to transmit imaging visible light of the third band, and the second visible light light source is used to output imaging visible light of the second band.

[0012] In one embodiment, the light source host includes a first visible light source and a second visible light source, the first visible light source is used to output imaging visible light in the second band to excite fluorescent dye, and the second visible light source is used to output imaging visible light in the third band.

[0013] In one embodiment, the fluorescent dye includes sodium fluorescein, the first waveband is at least a portion of the emission waveband range of sodium fluorescein, the second waveband is at least a portion of the excitation waveband range of sodium fluorescein, and the wavelength of the third waveband is greater than the wavelength of the emission waveband of sodium fluorescein.

[0014] In one embodiment, the fluorescent dye includes protoporphyrin, the first waveband is at least a partial waveband within the emission waveband range of protoporphyrin, the second waveband is at least a partial waveband within the excitation waveband range of protoporphyrin, and the wavelength of the third waveband is greater than the wavelength of the excitation waveband of protoporphyrin and less than the wavelength of the emission waveband of protoporphyrin.

[0015] In one embodiment, the fluorescent dye excited by visible light includes a first fluorescent dye and a second fluorescent dye; the light source host further includes a second filter assembly, the first filter assembly and the second filter assembly are movable filter assemblies, and the light source host further includes a driving device, the driving device is used to drive the first filter assembly and the second filter assembly to move, so as to enter and exit the light path;

[0016] Among them, the second filter component is used to filter out the imaging visible light of the fourth band in the visible light, and transmit the imaging visible light of the fifth band and the imaging visible light of the sixth band; the first band is at least a part of the band within the emission band range of the first fluorescent dye, the second band is at least a part of the band within the excitation band range of the first fluorescent dye, the fourth band is at least a part of the band within the emission band range of the second fluorescent dye, the fifth band is at least a part of the band within the excitation band range of the second fluorescent dye, and the sixth band is different from the fifth band and the fourth band.

[0017] In one embodiment, the first fluorescent dye includes sodium fluorescein, the first waveband is at least a portion of the emission waveband of sodium fluorescein, the second waveband is at least a portion of the excitation waveband of sodium fluorescein, and the wavelength of the third waveband is greater than the wavelength of the emission waveband of sodium fluorescein;

[0018] The second fluorescent dye includes protoporphyrin, the fourth band is at least a partial band within the emission band range of protoporphyrin, the fifth band is at least a partial band within the excitation band range of protoporphyrin, and the wavelength of the sixth band is greater than the wavelength of the excitation band of protoporphyrin and less than the wavelength of the emission band of protoporphyrin.

[0019] In one embodiment, the emission band of the sodium fluorescein is 500nm-600nm, and the excitation band of the sodium fluorescein is below 500nm.

[0020] In one embodiment, the emission band of the protoporphyrin is above 600 nm, and the excitation band of the protoporphyrin is below 450 nm.

[0021] In one embodiment, the visible light source includes a white light source and a monochromatic light source, and the imaging visible light includes at least a portion of white light output by the white light source and monochromatic light output by the monochromatic light source.

[0022] In one embodiment, the fluorescent dye includes protoporphyrin, and the monochromatic light source includes a blue light source.

[0023] In one embodiment, the light source host further includes a first light combining device, and the first optical filter assembly is disposed between the white light source and the first light combining device.

[0024] In one embodiment, the endoscope further comprises a third filter component for filtering out at least a portion of the excitation wavelength band from reflected light and fluorescence from the target object.

[0025] In one embodiment, the light source host further includes a near-infrared light source, which is used to output near-infrared light to excite fluorescent dyes excited by near-infrared light, and the light source host is used to output visible light and near-infrared light;

[0026] The light source host further includes a second light combining device for combining the near-infrared light and outputting the combined light to the endoscope;

[0027] The endoscope is also used to transmit the near-infrared light to a target object containing a fluorescent dye excited by the near-infrared light, receive near-infrared fluorescence from the target object, and generate a second electrical signal;

[0028] The camera host is also used to generate a near-infrared fluorescent image based on the second electrical signal;

[0029] The display is also used to display the near-infrared fluorescent image.

[0030] In one embodiment, the endoscope includes a first image sensor and a second image sensor, wherein the first image sensor is used to receive reflected light from the target object and visible light fluorescence emitted by a fluorescent dye excited by visible light, and generate the first electrical signal, and the second image sensor is used to receive near-infrared fluorescence emitted by a fluorescent dye excited by near-infrared light, and generate the second electrical signal;

[0031] The endoscope also includes a spectroscopic device for dividing the light from the target object into a first light path and a second light path, wherein the first light path includes reflected light from the target object and visible light fluorescence emitted by a fluorescent dye excited by visible light, and the second light path includes near-infrared fluorescence emitted by a fluorescent dye excited by near-infrared light.

[0032] In one embodiment, the third wavelength band is all wavelength bands in the white light wavelength band except the first wavelength band and the second wavelength band.

[0033] According to a second aspect of an embodiment of the present invention, there is provided a light source host of an endoscope imaging system, the light source host being used to output imaging visible light, the imaging visible light being used to excite a fluorescent dye excited by visible light, the imaging visible light excluding imaging visible light of a first band, and including imaging visible light of a second band and imaging visible light of a third band; wherein the first band is at least a portion of a band within an emission band interval of the fluorescent dye, the second band is at least a portion of a band within an excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band;

[0034] The light source host includes a visible light source and a first filter component, wherein the first filter component is used to filter out the imaging visible light of the first band output by the visible light source and transmit the imaging visible light of the second band and the imaging visible light of the third band.

[0035] In one embodiment, the fluorescent dye excited by visible light includes a first fluorescent dye and a second fluorescent dye; the light source host further includes a second filter assembly, the first filter assembly and the second filter assembly are movable filter assemblies, and the light source host further includes a driving device, the driving device is used to drive the first filter assembly and the second filter assembly to move, so as to enter and exit the light path;

[0036] Wherein, the second filter component is used to filter out the imaging visible light of the fourth band in the imaging visible light, and transmit the imaging visible light of the fifth band and the imaging visible light of the sixth band; wherein, the fourth band is the emission band of the second fluorescent dye, the fifth band is the excitation band of the second fluorescent dye, and the sixth band is different from the fifth band and the sixth band.

[0037] In one embodiment, the visible light source includes a white light source and a monochromatic light source, and the imaging visible light includes at least a portion of white light output by the white light source and monochromatic light output by the monochromatic light source.

[0038] In one embodiment, the light source host further includes a first light combining device, and the first optical filter assembly is disposed between the white light source and the first light combining device.

[0039] In one embodiment, the light source host further includes a near-infrared light source, which is used to output near-infrared light to excite fluorescent dyes excited by near-infrared light, and the light source host is used to output visible light and near-infrared light;

[0040] The light source host also includes a second light combining device for combining the visible light and the near-infrared light.

[0041] In one embodiment, the third wavelength band is all wavelength bands in the white light wavelength band except the first wavelength band and the second wavelength band.

[0042] According to a third aspect of an embodiment of the present invention, there is provided a light source host of an endoscope imaging system, the light source host being used to output imaging visible light to excite a fluorescent dye excited by the visible light, the imaging visible light comprising imaging visible light of a second band and imaging visible light of a third band, and excluding imaging visible light of a first band; wherein the first band is at least a portion of a band within an emission band interval of the fluorescent dye, the second band is at least a portion of a band within an excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band;

[0043] The light source host includes a first visible light source, a second visible light source and a first filter assembly, wherein the first filter assembly is used to filter out imaging visible light of a first band in the visible light output by the first visible light source, and transmit imaging visible light of a second band, and the second visible light source is used to output imaging visible light of a third band; or, the first filter assembly is used to filter out imaging visible light of a first band in the imaging visible light output by the first visible light source, and transmit imaging visible light of a third band, and the second visible light source is used to output imaging visible light of a second band.

[0044] A fourth aspect of an embodiment of the present invention provides a light source host of an endoscope imaging system, the light source host is used to output imaging visible light to excite a fluorescent dye excited by the visible light, the imaging visible light includes imaging visible light of a second band and imaging visible light of a third band, and does not include imaging visible light of the first band; wherein the first band is at least a portion of a band within an emission band interval of the fluorescent dye, the second band is at least a portion of a band within an excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band;

[0045] The light source host includes a first visible light source and a second visible light source, the first visible light source is used to output imaging visible light in the second wavelength band to excite fluorescent dye, and the second visible light source is used to output imaging visible light in the third wavelength band.

[0046] According to the embodiment of the present invention, the endoscopic imaging system and its light source host output visible light of the second band to excite fluorescent dyes, output visible light of the third band to improve the imaging effect of reflected light imaging, and do not output visible light of the first band to avoid crosstalk with the excitation light of the fluorescent dye. It is possible to realize visible light fluorescence imaging and reflected light imaging, and ensure the imaging effect of reflected light imaging. BRIEF DESCRIPTION OF THE DRAWINGS

[0047] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings in the following description are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative labor.

[0048] In the attached picture:

[0049] Figure 1 is a schematic block diagram of an endoscopic imaging system according to an embodiment of the present invention;

[0050] Figure 2 is a schematic diagram of a light source host according to an embodiment of the present invention;

[0051] Figure 3 is a schematic diagram of an endoscope according to an embodiment of the present invention;

[0052] Figure 4 shows a spectrum of sodium fluorescein according to an embodiment of the present invention;

[0053] Figure 5 shows a spectrum of protoporphyrin according to an embodiment of the present invention;

[0054] Figure 6 A schematic diagram of a light source host according to another embodiment of the present invention;

[0055] Figure 7 is a schematic diagram of an endoscope according to another embodiment of the present invention;

[0056] Figure 8 Spectra of sodium fluorescein and indocyanine green according to an embodiment of the present invention are shown;

[0057] Fig. 9 The spectrum of protoporphyrin and indocyanine green according to one embodiment of the present invention is shown. DETAILED DESCRIPTION

[0058] In order to make the purpose, technical scheme and advantages of the present invention more obvious, the exemplary embodiments according to the present invention will be described in detail with reference to the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments of the present invention, and it should be understood that the present invention is not limited to the exemplary embodiments described herein. Based on the embodiments of the present invention described in the present invention, all other embodiments obtained by those skilled in the art without creative work should fall within the protection scope of the present invention.

[0059] In the following description, a large number of specific details are provided to provide a more thorough understanding of the present invention. However, it is apparent to those skilled in the art that the present invention can be implemented without one or more of these details. In other examples, in order to avoid confusion with the present invention, some technical features well known in the art are not described.

[0060] It should be understood that the present invention can be implemented in different forms and should not be interpreted as limited to the embodiments set forth herein. On the contrary, these embodiments are provided to make the disclosure thorough and complete and to fully convey the scope of the present invention to those skilled in the art.

[0061] The purpose of the terms used herein is only to describe specific embodiments and is not intended to be limiting of the present invention. When used herein, the singular forms "one", "an" and "said / the" are also intended to include plural forms, unless the context clearly indicates otherwise. It should also be understood that the terms "consisting of" and / or "comprising", when used in this specification, determine the presence of the features, integers, steps, operations, elements and / or parts, but do not exclude the presence or addition of one or more other features, integers, steps, operations, elements, parts and / or groups. When used herein, the term "and / or" includes any and all combinations of the relevant listed items.

[0062] In order to fully understand the present invention, a detailed structure will be proposed in the following description to illustrate the technical solution proposed by the present invention. The optional embodiments of the present invention are described in detail as follows, but in addition to these detailed descriptions, the present invention may also have other implementations.

[0063] Below, reference Figures 1 to 9 An endoscopic imaging system according to an embodiment of the present invention is described. Figure 1As shown, the endoscopic imaging system 100 includes a light source host 110 , an endoscope 120 , a camera host 130 and a display 140 . Among them, the light source host 110 is used to output imaging visible light, and the imaging visible light is used to excite the fluorescent dye excited by the visible light and generate a reflected light image. The visible light does not include visible light in the first band, and includes visible light in the second band and visible light in the third band; wherein the first band is at least a part of the band within the emission band interval of the fluorescent dye, the second band is at least a part of the band within the excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band; the endoscope 120 is used to transmit the imaging visible light output by the light source host 110 to the target object containing the fluorescent dye excited by the visible light, receive the reflected light and visible light fluorescence from the target object, and generate a first electrical signal; the camera host 130 is connected to the endoscope 120, and is used to separate the reflected light signal and the visible light fluorescence signal from the first electrical signal, and the camera host 130 generates a reflected light image based on the reflected light signal, and generates a visible light fluorescence image based on the visible light fluorescence signal; the display 140 is used to display the reflected light image and / or the visible light fluorescence image.

[0064] The light source host 110 of the endoscopic imaging system 100 of the embodiment of the present invention outputs imaging visible light with a wider band, which includes at least part of the band within the excitation band range of the fluorescent dye, which is used to excite the fluorescent dye excited by the visible light, and does not include at least part of the band within the emission band range of the fluorescent dye, which can avoid crosstalk to the fluorescence generated by the excited fluorescent dye; the imaging visible light output by the light source host 110 also includes an additional third band, which can ensure the tissue structure and color of the reflected light image; the camera host 130 separates the reflected light signal and the visible light fluorescence signal from the first electrical signal generated by the endoscope 120, so that reflected light imaging and visible light fluorescence imaging can be performed simultaneously.

[0065] In one embodiment, the third band is all the bands in the white light band except the first band and the second band. The white light band is all the visible light bands, for example, the white light band is the 400nm-760nm band. Different from the existing designs that only retain narrow-band light as the excitation light for fluorescent dyes, the embodiment of the present invention only removes the third band in the white light band corresponding to the visible light fluorescent dye excitation band interval, retaining most of the broadband white light band, which can maximize the brightness and color of the non-fluorescent area, making it easier for users to see the texture structure of the tissue surface, without the need to frequently switch the lighting mode to obtain fluorescence and white light images to confirm the diagnosis results.

[0066] In one embodiment, the light source host 110 includes a visible light source and a first filter assembly 112, wherein the first filter assembly is used to filter out the imaging visible light of the first band in the imaging visible light output by the visible light source, and transmit the imaging visible light of the second band and the imaging visible light of the third band. The visible light source may be a white light source, which is a full-spectrum visible light source. Exemplarily, the white light source outputs visible light in the 400nm-760nm band. The white light source may include a white light LED. The first filter assembly is disposed at the front end of the visible light source, and is used to filter out the imaging visible light of the first band therefrom, so as to avoid crosstalk to the fluorescence emitted by the fluorescent dye.

[0067] In another embodiment, the light source host 110 includes a first visible light source, a second visible light source, and a first filter assembly. The first filter assembly is used to filter out the imaging visible light of the first band output by the first visible light source, and transmit the imaging visible light of the second band, and the second visible light source is used to output the imaging visible light of the third band. Alternatively, the first filter assembly is used to filter out the imaging visible light of the first band in the imaging visible light output by the first visible light source, and transmit the imaging visible light of the third band, and the second visible light source is used to output the imaging visible light of the second band. In this embodiment, the first visible light source is a visible light source with a wider band, the first filter assembly is used to filter it to filter out the imaging visible light of the first band, the second filter assembly is used to supplement the imaging visible light of the third band to improve the color and brightness of the reflected light image and enrich the tissue details therein, or the second filter assembly is used to supplement the imaging visible light of the second band to excite the visible light fluorescent dye.

[0068] In another embodiment, the light source host 110 includes a first visible light source and a second visible light source, wherein the first visible light source is used to output imaging visible light of a second wavelength band to excite fluorescent dyes, and the second visible light source is used to output imaging visible light of a third wavelength band. In this embodiment, the first visible light source and the second visible light source are used to excite fluorescent dyes and fill light, respectively, and there is no need to set a filter component, which is conducive to reducing the size of the device and reducing costs.

[0069] The imaging visible light output by the light source host 110 is transmitted by the endoscope 120 to the patient's part to be observed. The endoscope 120 is also used to receive light returned from the part to be observed, including visible light fluorescence generated by the excitation of the visible light fluorescent dye and reflected light of the imaging visible light. The endoscope 120 includes an insertion portion and an operating portion, the insertion portion is used to be inserted into the patient's part to be observed, and the operating portion is used for handheld operation by the user, and the insertion portion and the operating portion can be an integrated structure or a detachable structure. The endoscope 120 also includes at least one image sensor for generating a first electrical signal based on the visible light fluorescence and the reflected light.

[0070] The other end of the endoscope 120 is connected to the camera host 130 through a cable, and the first electrical signal is transmitted to the camera host 130 through the cable for processing. In some embodiments, the endoscope 120 can also send the first electrical signal to the camera host 130 by wireless transmission. The camera host 130 generates a reflected light image and a visible light fluorescence image based on the first electrical signal, wherein the reflected light image is generated by the reflected light of the imaging visible light with a missing part of the wavelength band, and the visible light fluorescence image is generated by the fluorescence generated by the excitation of the visible light fluorescent dye.

[0071] For example, Figure 3 As shown, the endoscope 120 can receive visible light fluorescence and reflected light based on the same first image sensor 121, and the first electrical signal contains visible light fluorescence components and reflected light components, that is, the endoscope 120 does not need to distinguish between visible light fluorescence and reflected light, so there is no need to set up a spectroscopic device. In this example, the camera host 130 separates the visible light fluorescence signal and the visible light signal through an algorithm after receiving the first electrical signal. Optionally, the endoscope 120 can also generate visible light signals and visible light fluorescence signals based on different image sensors, that is, the electrical signal contains visible light fluorescence signals and visible light signals, and the camera host 130 does not need to decouple through an algorithm.

[0072] The display 140 is connected to the camera host 130, and is used to display the visible light fluorescence image and / or the reflected light image generated by the camera host 130. Specifically, the camera host 130 can be connected to the display 140 via a video connection line, and is used to send the visible light fluorescence image and / or the reflected light image to the display 140 for display. The display 140 can display the visible light fluorescence image and the reflected light image in a superimposed or fused manner; or the display 140 can display the visible light fluorescence image and the reflected light image separately. Optionally, the display 140 can also display only the visible light fluorescence image or only the reflected light image.

[0073] In a specific example, the fluorescent dye excited by visible light includes sodium fluoresceinsodium (FLS), and the second band in the imaging visible light output by the light source host 110 is at least part of the band within the excitation band interval of sodium fluorescein, which is used to excite sodium fluorescein, and the wavelength of the third band other than the second band is greater than the wavelength of the emission band of sodium fluorescein. The imaging visible light does not include at least part of the band (i.e., the first band) within the emission band interval of sodium fluorescein to avoid crosstalk with the emission light of sodium fluorescein.

[0074] See also Figure 4 , which shows the emission spectrum, excitation spectrum and corresponding light transmission band of the first filter component of fluorescein sodium. Figure 4As shown, the emission band of sodium fluorescein is the 500nm-600nm band, and the excitation band of sodium fluorescein is the band below 500nm. Therefore, when imaging sodium fluorescein, the imaging visible light output by the light source host 110 does not include the 500nm-600nm band (i.e., the first band), and in addition to the band below 500nm (i.e., the second band) required to excite sodium fluorescein, it also includes an additional 600nm-750nm band (i.e., the third band). In general, when imaging sodium fluorescein, the imaging visible light output by the light source host 110 includes the 400nm-500nm band and the 600nm-750nm band. Since the light source host 110 does not filter out all light outside the 400nm-500nm band, the brightness and color of the reflected light imaging are improved.

[0075] In another example, the fluorescent dye includes protoporphyrin (Protoporphyrin IX, PPIX), and the imaging visible light includes visible light of at least a portion of the wavelength band (i.e., the second wavelength band) within the excitation wavelength band of protoporphyrin, which is used to excite protoporphyrin, and in addition to the visible light of the second wavelength band, it also includes visible light of a third wavelength band, and the wavelength of the third wavelength band is greater than the wavelength of the excitation wavelength band of protoporphyrin and less than the wavelength of the emission wavelength band of protoporphyrin. The imaging visible light does not include visible light of the first wavelength band to avoid crosstalk with the emission light of protoporphyrin, and the first wavelength band is at least a portion of the wavelength band within the emission wavelength band of protoporphyrin.

[0076] See also Figure 5 , which shows the emission spectrum, excitation spectrum and corresponding light transmission band of the first filter component of protoporphyrin. Figure 5 As shown, the emission band of protoporphyrin is a band above 600nm, specifically a band of 600nm-750nm; the excitation band of protoporphyrin is a band below 450nm, specifically a band of 400nm-450nm. Therefore, when protoporphyrin is imaged, the imaging visible light output by the light source host 110 does not include the 600nm-750nm band (i.e., the first band), and in addition to the 400nm-450nm band (i.e., the second band) required for exciting protoporphyrin, it also includes an additional 450nm-600nm band (i.e., the third band). In general, when protoporphyrin is imaged, the imaging visible light output by the light source host 110 includes the 400nm-600nm band. Since the light source host 110 does not filter out all the light outside the 400nm-450nm band, the brightness and color of the reflected light imaging are improved.

[0077] It should be noted that the emission band and excitation band of the fluorescent dye generally present a normal distribution curve, the first band can be the entire band of the emission band or cover most of the emission band, the second band can be the entire band of the excitation band or cover most of the excitation band. The third band does not overlap with the first band and the second band at all or may overlap partially.

[0078] In some embodiments, the first filter assembly may completely filter out the imaging visible light of the first band from the white light to avoid crosstalk, or the first filter assembly may also transmit a partial proportion of the imaging visible light of the first band to ensure the color of the reflected light image. For example, in the sodium fluorescein imaging mode, the first filter assembly may not completely filter out the visible light of the sodium fluorescein emission band (500nm to 600nm), but transmit a partial proportion (e.g., 1 / 1000) of the visible light of this band. In the protoporphyrin imaging mode, the first filter assembly may not completely filter out the visible light of the protoporphyrin emission band (600nm to 750nm), but transmit a partial proportion (e.g., 1 / 1000) of the visible light of this band.

[0079] In some embodiments, reference Figure 2 The visible light source 110 includes a white light source 111 and a monochromatic light source 113, and the imaging visible light 111 includes at least part of the white light output by the white light source and the monochromatic light output by the monochromatic light source 113. A first filter assembly 112 is provided at the front end of the white light source 111 to filter out the visible light of the first wavelength band. The monochromatic light output by the monochromatic light source 113 corresponds to the second wavelength band, i.e., at least part of the wavelength band within the excitation wavelength band of the fluorescent dye, and is used to improve the excitation effect of the fluorescent dye.

[0080] For example, when the fluorescent dye is protoporphyrin, since its excitation band is 400nm-450nm, ie, blue light band, the monochromatic light source 113 includes a blue light source for providing monochromatic light in the 400nm-450nm band.

[0081] The light source host 110 also includes a first light combining device 114, and a first filter assembly 112 is disposed between the white light source 111 and the first light combining device 114. After the visible light of the first band is filtered out by the first filter assembly 112, the white light output by the white light source 111 is combined with the monochromatic light output by the monochromatic light source 113 through the first light combining device 114. Exemplarily, the first light combining device 114 can be a dichroic mirror obliquely disposed between the white light source 111 and the monochromatic light source 113, and the optical path direction of the monochromatic light irradiated onto the surface of the first light combining device 114 changes; while the optical path direction of the white light does not change; therefore, the monochromatic light reflected by the first light combining device 114 and the transmitted white light change to the same direction, thereby forming a composite light beam.

[0082] In some embodiments, the endoscope 120 further includes a third filter assembly 122 for filtering out at least a portion of the wavelength band within the excitation wavelength band from the reflected light and fluorescence from the target object. When the light source host 110 further includes a monochromatic light source 113, the third filter assembly 122 can filter out a portion of the visible light of the wavelength band corresponding to the monochromatic light source 113 to prevent the monochromatic light source 113 from excessively affecting the color of the reflected light image.

[0083] Exemplarily, the third filter assembly 122 may completely filter out the light within the excitation wavelength range, or may retain a partial proportion (eg, 1 / 10) of the light within the wavelength range to improve the imaging effect of reflected light imaging.

[0084] In some embodiments, the endoscopic imaging system can also support fluorescent imaging of at least two fluorescent dyes excited by visible light. Among them, the fluorescent dyes excited by visible light include a first fluorescent dye and a second fluorescent dye. In this embodiment, the light source host 110 includes a first filter assembly and a second filter assembly, and the first filter assembly and the second filter assembly are movable filter assemblies. The light source host 110 also includes a driving device, which is used to drive the first filter assembly and the second filter assembly to move in and out of the light path. When the first filter assembly enters the light path, the second filter assembly leaves the light path, and the imaging visible light is filtered by the first filter assembly; when the second filter assembly enters the light path, the first filter assembly leaves the light path, and the imaging visible light is filtered by the second filter assembly.

[0085] The first filter assembly is used to filter out the imaging visible light of the first wavelength band in the imaging visible light output by the visible light source, and transmit the imaging visible light of the second wavelength band and the imaging visible light of the third wavelength band. The first wavelength band is at least a portion of the wavelength band within the emission wavelength band interval of the first fluorescent dye, the second wavelength band is at least a portion of the wavelength band within the excitation wavelength band interval of the first fluorescent dye, and the third wavelength band is different from the first wavelength band and the second wavelength band. That is, when imaging the first fluorescent dye, the first filter assembly enters the optical path and filters out at least a portion of the wavelength band within the emission wavelength band interval of the first fluorescent dye in the imaging visible light output by the visible light source.

[0086] The second filter assembly is used to filter out the imaging visible light in the fourth wavelength band of the visible light, and transmit the imaging visible light in the fifth wavelength band and the imaging visible light in the sixth wavelength band. The fourth wavelength band is at least a portion of the wavelength band within the emission wavelength band of the second fluorescent dye, the fifth wavelength band is at least a portion of the wavelength band within the excitation wavelength band of the second fluorescent dye, and the sixth wavelength band is different from the fifth wavelength band and the fourth wavelength band. That is, when imaging the second fluorescent dye, the second filter assembly enters the optical path and filters out at least a portion of the wavelength band within the emission wavelength band of the second fluorescent dye in the imaging visible light output by the visible light source.

[0087] Exemplarily, the first fluorescent dye and the second fluorescent dye are sodium fluorescein and protoporphyrin, respectively. The first band filtered by the first filter assembly is at least part of the band within the emission band of sodium fluorescein, the second band passed is at least part of the band within the excitation band of sodium fluorescein, and the wavelength of the third band is greater than the wavelength of the emission band of sodium fluorescein. The fourth band filtered by the second filter assembly is at least part of the band within the emission band of protoporphyrin, the fifth band passed is at least part of the band within the excitation band of protoporphyrin, and the wavelength of the sixth band is greater than the wavelength of the excitation band of protoporphyrin and less than the wavelength of the emission band of protoporphyrin. Exemplarily, when the visible light source is a white light source, the stop band of the first filter assembly is the 500nm-600nm band, and the stop band of the second filter assembly is the 600nm-750nm band.

[0088] In some embodiments, Figure 6 As shown, the light source host 110 also includes a near-infrared light source 115, which is used to output near-infrared light to excite the fluorescent dye excited by the near-infrared light. The light source host 110 can output visible light and near-infrared light in a time-sharing or simultaneous manner; the light source host 110 also includes a second light combining device 116, which is used to combine the near-infrared light and output it to the endoscope 120; the endoscope 120 is also used to transmit the near-infrared light to a target object containing a fluorescent dye excited by the near-infrared light, receive the near-infrared fluorescence from the target object, and generate a second electrical signal; the camera host 130 is also used to generate a near-infrared fluorescence image based on the second electrical signal; the display 140 is also used to display the near-infrared fluorescence image.

[0089] exist Figure 6 In the example, the white light output by the white light source 111 is filtered by the first filter assembly 112 and then combined with the monochromatic light output by the monochromatic light source 113 to obtain synthetic visible light; the synthetic visible light is combined with the near-infrared light output by the near-infrared light source 115 through the second light combining device 116 and then output to the endoscope.

[0090] For example, when visible light imaging and near infrared light imaging are supported, different image sensors may be used to perform visible light imaging and near infrared light imaging, respectively. Figure 7, the endoscope may include a first image sensor 121 and a second image sensor 123, wherein the first image sensor 121 is used to receive reflected light from the target object and visible light fluorescence emitted by the fluorescent dye excited by visible light, and generate a first electrical signal, and the second image sensor is used to receive near-infrared fluorescence emitted by the fluorescent dye excited by near-infrared light, and generate a second electrical signal. After receiving the first electrical signal, the camera host 130 decouples it to separate the reflected light signal and the visible light fluorescence signal, and generates a reflected light image and a visible light fluorescence image respectively, and generates a near-infrared fluorescence image based on the second electrical signal. The display 140 can simultaneously output a superimposed image of the reflected light image and the visible light fluorescence and a superimposed image of the reflected light image and the near-infrared fluorescence image.

[0091] The endoscope 120 further includes a spectroscopic device 124 for dividing the light from the target object into a first light path and a second light path, wherein the first light path includes reflected light from the target object and visible light fluorescence emitted by a fluorescent dye excited by visible light, and the second light path includes near-infrared fluorescence emitted by a fluorescent substance excited by near-infrared light. By setting the first image sensor 121 and the second image sensor 123 to collect different image signals respectively, the endoscope imaging system of the embodiment of the present invention can simultaneously perform visible light imaging and near-infrared light imaging.

[0092] In one embodiment, the fluorescent dye excited by near infrared light includes indocyanine green. Figure 8 The spectrum diagram when imaging sodium fluorescein and indocyanine green simultaneously is shown; Fig. 9 The spectra of protoporphyrin and indocyanine green were simultaneously imaged.

[0093] like Figure 8 As shown, when imaging sodium fluorescein and indocyanine green at the same time, the emission band of sodium fluorescein is filtered out in the visible light band and the remaining bands are transmitted to excite sodium fluorescein and perform reflected light imaging; while the emission band of indocyanine green is filtered out in the near-infrared band, the excitation band of indocyanine green is transmitted to excite indocyanine green.

[0094] like Fig. 9 As shown, when imaging protoporphyrin and indocyanine green at the same time, the emission band of protoporphyrin is filtered out in the visible light band and the remaining bands are transmitted, and the blue light source emits blue light to excite protoporphyrin and perform reflected light imaging; the emission band of indocyanine green is filtered out in the near-infrared band, and the excitation band of indocyanine green is transmitted to excite indocyanine green.

[0095] It should be noted that the embodiment of the present invention is described by taking an endoscope imaging system as an example, but it also includes an exoscopic system.

[0096] To summarize, the endoscopic imaging system of the embodiment of the present invention outputs visible light of the second band through the light source host to excite fluorescent dyes, outputs visible light of the third band to improve the imaging effect of reflected light imaging, and does not output visible light of the first band to avoid crosstalk with the excitation light of the fluorescent dye. It can realize visible light fluorescence imaging and reflected light imaging, and ensure the imaging effect of reflected light imaging.

[0097] On the other hand, an embodiment of the present invention provides a light source host of an endoscope imaging system, which is used to output imaging visible light, and the imaging visible light is used to excite fluorescent dyes excited by visible light. The imaging visible light does not include imaging visible light in a first band, and includes imaging visible light in a second band and imaging visible light in a third band; wherein the first band is at least a portion of the band within the emission band range of the fluorescent dye, the second band is at least a portion of the band within the excitation band range of the fluorescent dye, and the third band is different from the first band and the second band.

[0098] As an implementation method, the light source host includes a visible light source and a first filter component, wherein the first filter component is used to filter out the imaging visible light of the first band output by the visible light source, and transmit the imaging visible light of the second band and the imaging visible light of the third band. The visible light source may be a white light source, and the third band may be all bands of the white light band except the first band and the second band.

[0099] In another implementation, the light source host includes a first visible light light source, a second visible light light source and a first filter assembly, the first filter assembly is used to filter out imaging visible light of a first band in the visible light output by the first visible light light source, and transmit imaging visible light of a second band, and the second visible light light source is used to output imaging visible light of a third band; or, the first filter assembly is used to filter out imaging visible light of a first band in the imaging visible light output by the first visible light light source, and transmit imaging visible light of a third band, and the second visible light light source is used to output imaging visible light of a second band.

[0100] In a third implementation, the light source host is used to output imaging visible light to excite fluorescent dyes excited by visible light, and the imaging visible light includes imaging visible light of a second band and imaging visible light of a third band, and does not include imaging visible light of the first band; wherein the first band is at least a portion of a band within an emission band range of the fluorescent dye, the second band is at least a portion of a band within an excitation band range of the fluorescent dye, and the third band is different from the first band and the second band; the light source host includes a first visible light source and a second visible light source, the first visible light source is used to output imaging visible light of the second band to excite the fluorescent dye, and the second visible light source is used to output imaging visible light of the third band.

[0101] Exemplarily, the fluorescent dye excited by visible light includes a first fluorescent dye and a second fluorescent dye; the light source host also includes a second filter assembly, the first filter assembly and the second filter assembly are movable filter assemblies, and the light source host also includes a driving device, the driving device is used to drive the first filter assembly and the second filter assembly to move in and out of the light path; wherein, the second filter assembly is used to filter out the imaging visible light in the fourth band of the imaging visible light, and pass the imaging visible light in the fifth band and the imaging visible light in the sixth band; wherein, the fourth band is the emission band of the second fluorescent dye, the fifth band is the excitation band of the second fluorescent dye, and the sixth band is different from the fifth band and the sixth band.

[0102] Exemplarily, the visible light source includes a white light source and a monochromatic light source, and the imaged visible light includes at least a portion of the white light output by the white light source and the monochromatic light output by the monochromatic light source.

[0103] Exemplarily, the light source host further includes a first light combining device, the first filter assembly is arranged between the white light source and the first light combining device, and the first light combining device is used to combine the filtered white light and the monochromatic light.

[0104] Furthermore, the light source host may also include a near-infrared light source, which is used to output near-infrared light to excite fluorescent dyes excited by near-infrared light, and the light source host is used to output visible light and near-infrared light; the light source host also includes a second light combining device, which is used to combine visible light and near-infrared light.

[0105] The light source host of the embodiment of the present invention outputs visible light in the excitation band of the fluorescent dye, and does not output visible light in the emission band of the fluorescent dye, and the imaging visible light output by the light source host also includes an additional visible light in the third band, which can simultaneously realize reflected light imaging and visible light imaging, and ensure the color and brightness of reflected light imaging.

[0106] Although example embodiments have been described herein with reference to the accompanying drawings, it should be understood that the above example embodiments are merely exemplary and are not intended to limit the scope of the present invention thereto. Various changes and modifications may be made therein by one of ordinary skill in the art without departing from the scope and spirit of the present invention. All such changes and modifications are intended to be included within the scope of the present invention as required by the appended claims.

[0107] Those skilled in the art will appreciate that the units and algorithm steps of each example described in conjunction with the embodiments disclosed herein can be implemented in electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Professional and technical personnel can use different methods to implement the described functions for each specific application, but such implementation should not be considered to be beyond the scope of the present invention.

[0108] In the several embodiments provided by the present invention, it should be understood that the disclosed devices and methods can be implemented in other ways. For example, the device embodiments described above are only schematic, for example, the division of units is only a logical function division, and there may be other division methods in actual implementation, such as multiple units or components can be combined or integrated into another device, or some features can be ignored or not executed.

[0109] In the description provided herein, a large number of specific details are described. However, it is understood that embodiments of the present invention can be practiced without these specific details. In some instances, well-known methods, structures and techniques are not shown in detail so as not to obscure the understanding of this description.

[0110] Similarly, it should be understood that in order to streamline the present invention and help understand one or more of the various inventive aspects, in the description of the exemplary embodiments of the present invention, the various features of the present invention are sometimes grouped together into a single embodiment, figure, or description thereof. However, the method of the present invention should not be interpreted as reflecting the following intention: the claimed invention requires more features than the features explicitly stated in each claim. More specifically, as reflected in the corresponding claims, the inventive point is that the corresponding technical problem can be solved with less than all the features of a single disclosed embodiment. Therefore, the claims following the specific embodiment are hereby expressly incorporated into the specific embodiment, wherein each claim itself serves as a separate embodiment of the present invention.

[0111] It will be understood by those skilled in the art that, except for mutually exclusive features, all features disclosed in this specification (including the accompanying claims, abstracts and drawings) and all processes or units of any method or device disclosed in this specification may be combined in any combination. Unless otherwise expressly stated, each feature disclosed in this specification (including the accompanying claims, abstracts and drawings) may be replaced by an alternative feature that provides the same, equivalent or similar purpose.

[0112] In addition, those skilled in the art will appreciate that, although some embodiments herein include certain features included in other embodiments but not other features, the combination of features of different embodiments is meant to be within the scope of the present invention and form different embodiments. For example, in the claims, any one of the claimed embodiments may be used in any combination.

[0113] The various component embodiments of the present invention can be implemented in hardware, or in software modules running on one or more processors, or in a combination thereof. It should be understood by those skilled in the art that a microprocessor or digital signal processor (DSP) can be used in practice to implement some or all of the functions of some modules according to embodiments of the present invention. The present invention can also be implemented as a device program (e.g., a computer program and a computer program product) for executing part or all of the methods described herein. Such a program implementing the present invention can be stored on a computer-readable medium, or can have the form of one or more signals. Such a signal can be downloaded from an Internet website, or provided on a carrier signal, or provided in any other form.

[0114] It should be noted that the above embodiments illustrate rather than limit the invention, and that those skilled in the art may devise alternative embodiments without departing from the scope of the appended claims. In the claims, any reference symbol between brackets shall not be construed as a limitation on the claims. The invention may be implemented by means of hardware comprising a number of different elements and by means of a suitably programmed computer. In a unit claim enumerating a number of means, several of these means may be embodied by the same hardware item. The use of the words first, second, and third, etc., does not indicate any order. These words may be interpreted as names.

[0115] The above is only a specific embodiment or description of a specific embodiment of the present invention, and the protection scope of the present invention is not limited thereto. Any person skilled in the art who is familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. The protection scope of the present invention shall be based on the protection scope of the claims.

Claims

1. An endoscopic imaging system, characterized in that: It includes a light source host, an endoscope, a camera host and a display, among which: The light source host is used to output imaging visible light, and the imaging visible light is used to excite the fluorescent dye excited by the visible light and generate a reflected light image, and the imaging visible light does not include visible light in the first band, and includes visible light in the second band and visible light in the third band; wherein the first band is at least a part of the band within the emission band interval of the fluorescent dye, the second band is at least a part of the band within the excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band; The endoscope is used to transmit the imaging visible light output by the light source host to the target object containing the fluorescent dye excited by the visible light, receive the reflected light and visible light fluorescence from the target object, and generate a first electrical signal; The camera host is connected to the endoscope and is used to separate the reflected light signal and the visible light fluorescence signal from the first electrical signal, and the camera host generates a reflected light image based on the reflected light signal and generates a visible light fluorescence image based on the visible light fluorescence signal; The display is used for displaying the reflected light image and / or the visible light fluorescent image.

2. The endoscopic imaging system according to claim 1, characterized in that: The light source host includes a visible light source and a first filter component, wherein the first filter component is used to filter out imaging visible light of the first band in the imaging visible light output by the visible light source, and to transmit imaging visible light of the second band and imaging visible light of the third band.

3. The endoscopic imaging system according to claim 1, characterized in that: The light source host comprises a first visible light source, a second visible light source and a first filter assembly, wherein the first filter assembly is used to filter out the imaging visible light of the first wavelength band output by the first visible light source and transmit the imaging visible light of the second wavelength band, and the second visible light source is used to output the imaging visible light of the third wavelength band; Alternatively, the first filter assembly is used to filter out imaging visible light of the first band in the imaging visible light output by the first visible light light source, and to transmit imaging visible light of the third band, and the second visible light light source is used to output imaging visible light of the second band.

4. The endoscopic imaging system according to claim 1, characterized in that: The light source host includes a first visible light source and a second visible light source, the first visible light source is used to output imaging visible light in the second wavelength band to excite fluorescent dye, and the second visible light source is used to output imaging visible light in the third wavelength band.

5. The endoscopic imaging system according to claim 1, characterized in that: The fluorescent dye includes sodium fluorescein, the first waveband is at least a part of the emission waveband of sodium fluorescein, the second waveband is at least a part of the excitation waveband of sodium fluorescein, and the wavelength of the third waveband is greater than the wavelength of the emission waveband of sodium fluorescein.

6. The endoscopic imaging system according to claim 1, characterized in that: The fluorescent dye includes protoporphyrin, the first waveband is at least a part of the waveband within the emission waveband range of protoporphyrin, the second waveband is at least a part of the waveband within the excitation waveband range of protoporphyrin, and the wavelength of the third waveband is greater than the wavelength of the excitation waveband of protoporphyrin and less than the wavelength of the emission waveband of protoporphyrin.

7. The endoscopic imaging system according to claim 2, characterized in that: The fluorescent dye excited by visible light includes a first fluorescent dye and a second fluorescent dye; the light source host also includes a second filter assembly, the first filter assembly and the second filter assembly are movable filter assemblies, and the light source host also includes a driving device, the driving device is used to drive the first filter assembly and the second filter assembly to move, so as to enter and exit the light path; Among them, the second filter component is used to filter out the imaging visible light of the fourth band in the visible light, and transmit the imaging visible light of the fifth band and the imaging visible light of the sixth band; the first band is at least a part of the band within the emission band range of the first fluorescent dye, the second band is at least a part of the band within the excitation band range of the first fluorescent dye, the fourth band is at least a part of the band within the emission band range of the second fluorescent dye, the fifth band is at least a part of the band within the excitation band range of the second fluorescent dye, and the sixth band is different from the fifth band and the fourth band.

8. The endoscopic imaging system according to claim 7, characterized in that: The first fluorescent dye includes sodium fluorescein, the first waveband is at least a portion of the emission waveband of sodium fluorescein, the second waveband is at least a portion of the excitation waveband of sodium fluorescein, and the wavelength of the third waveband is greater than the wavelength of the emission waveband of sodium fluorescein; The second fluorescent dye includes protoporphyrin, the fourth band is at least a partial band within the emission band range of protoporphyrin, the fifth band is at least a partial band within the excitation band range of protoporphyrin, and the wavelength of the sixth band is greater than the wavelength of the excitation band of protoporphyrin and less than the wavelength of the emission band of protoporphyrin.

9. The endoscopic imaging system according to claim 5 or 8, characterized in that: The emission band of the sodium fluorescein is 500nm-600nm, and the excitation band of the sodium fluorescein is below 500nm.

10. The endoscopic imaging system according to claim 6 or 8, characterized in that: The emission band of the protoporphyrin is above 600nm, and the excitation band of the protoporphyrin is below 450nm.

11. The endoscopic imaging system according to claim 2, characterized in that: The visible light source includes a white light source and a monochromatic light source, and the imaging visible light includes at least a portion of white light output by the white light source and monochromatic light output by the monochromatic light source.

12. The endoscopic imaging system according to claim 11, characterized in that: The fluorescent dye includes protoporphyrin, and the monochromatic light source includes a blue light source.

13. The endoscopic imaging system according to claim 11, characterized in that: The light source host further includes a first light combining device, and the first optical filter assembly is arranged between the white light source and the first light combining device.

14. The endoscopic imaging system according to claim 11, characterized in that: The endoscope further comprises a third filter component for filtering out at least a portion of the excitation wavelength band from reflected light and fluorescence from the target object.

15. The endoscopic imaging system according to claim 1, characterized in that: The light source host also includes a near-infrared light source, which is used to output near-infrared light to excite the fluorescent dye excited by the near-infrared light, and the light source host is used to output visible light and near-infrared light; The light source host further includes a second light combining device for combining the near-infrared light and outputting the combined light to the endoscope; The endoscope is also used to transmit the near-infrared light to a target object containing a fluorescent dye excited by the near-infrared light, receive near-infrared fluorescence from the target object, and generate a second electrical signal; The camera host is also used to generate a near-infrared fluorescent image based on the second electrical signal; The display is also used to display the near-infrared fluorescent image.

16. The endoscopic imaging system according to claim 15, characterized in that: The endoscope comprises a first image sensor and a second image sensor, wherein the first image sensor is used to receive reflected light from the target object and visible light fluorescence emitted by a fluorescent dye excited by visible light, and generate the first electrical signal, and the second image sensor is used to receive near-infrared fluorescence emitted by a fluorescent dye excited by near-infrared light, and generate the second electrical signal; The endoscope also includes a spectroscopic device for dividing the light from the target object into a first light path and a second light path, wherein the first light path includes reflected light from the target object and visible light fluorescence emitted by a fluorescent dye excited by visible light, and the second light path includes near-infrared fluorescence emitted by a fluorescent dye excited by near-infrared light.

17. The endoscopic imaging system according to claim 1, characterized in that: The third wavelength band is all wavelength bands in the white light wavelength band except the first wavelength band and the second wavelength band.

18. A light source host of an endoscope imaging system, characterized in that: The light source host is used to output imaging visible light, and the imaging visible light is used to excite the fluorescent dye excited by the visible light, and the imaging visible light does not include the imaging visible light of the first band, and includes the imaging visible light of the second band and the imaging visible light of the third band; wherein the first band is at least a part of the band within the emission band interval of the fluorescent dye, the second band is at least a part of the band within the excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band; The light source host includes a visible light source and a first filter component, wherein the first filter component is used to filter out the imaging visible light of the first band output by the visible light source and transmit the imaging visible light of the second band and the imaging visible light of the third band.

19. The light source host according to claim 18, characterized in that: The fluorescent dye excited by visible light includes a first fluorescent dye and a second fluorescent dye; the light source host also includes a second filter assembly, the first filter assembly and the second filter assembly are movable filter assemblies, and the light source host also includes a driving device, the driving device is used to drive the first filter assembly and the second filter assembly to move, so as to enter and exit the light path; Wherein, the second filter component is used to filter out the imaging visible light of the fourth band in the imaging visible light, and transmit the imaging visible light of the fifth band and the imaging visible light of the sixth band; wherein, the fourth band is the emission band of the second fluorescent dye, the fifth band is the excitation band of the second fluorescent dye, and the sixth band is different from the fifth band and the sixth band.

20. The light source host according to claim 18, characterized in that: The visible light source includes a white light source and a monochromatic light source, and the imaging visible light includes at least a portion of white light output by the white light source and monochromatic light output by the monochromatic light source.

21. The light source host according to claim 20, characterized in that: The light source host further includes a first light combining device, and the first optical filter assembly is arranged between the white light source and the first light combining device.

22. The light source host according to claim 18, characterized in that: The light source host also includes a near-infrared light source, which is used to output near-infrared light to excite the fluorescent dye excited by the near-infrared light, and the light source host is used to output visible light and near-infrared light; The light source host also includes a second light combining device for combining the visible light and the near-infrared light.

23. The light source host according to claim 18, characterized in that: The third wavelength band is all wavelength bands in the white light wavelength band except the first wavelength band and the second wavelength band.

24. A light source host of an endoscope imaging system, characterized in that: The light source host is used to output imaging visible light to excite the fluorescent dye excited by the visible light, and the imaging visible light includes imaging visible light of the second band and imaging visible light of the third band, and does not include imaging visible light of the first band; wherein the first band is at least a part of the band within the emission band interval of the fluorescent dye, the second band is at least a part of the band within the excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band; The light source host includes a first visible light source, a second visible light source and a first filter assembly, wherein the first filter assembly is used to filter out imaging visible light of a first band in the visible light output by the first visible light source, and transmit imaging visible light of a second band, and the second visible light source is used to output imaging visible light of a third band; or, the first filter assembly is used to filter out imaging visible light of a first band in the imaging visible light output by the first visible light source, and transmit imaging visible light of a third band, and the second visible light source is used to output imaging visible light of a second band.

25. A light source host of an endoscope imaging system, characterized in that: The light source host is used to output imaging visible light to excite the fluorescent dye excited by the visible light, and the imaging visible light includes imaging visible light of the second band and imaging visible light of the third band, and does not include imaging visible light of the first band; wherein the first band is at least a part of the band within the emission band interval of the fluorescent dye, the second band is at least a part of the band within the excitation band interval of the fluorescent dye, and the third band is different from the first band and the second band; The light source host includes a first visible light source and a second visible light source, the first visible light source is used to output imaging visible light in the second wavelength band to excite fluorescent dye, and the second visible light source is used to output imaging visible light in the third wavelength band.

Images