Immunotherapy device and method for in-vivo individualized system

Abstract

The invention provides an immunotherapy device and method for an in-vivo individualized system.The immunotherapy device comprises a main bandage, a massage assembly is installed on the lower surface of the main bandage, and a magnetic therapy belt is installed on the portion, located on the outer side of the massage assembly, of the lower surface of the main bandage; a feeding structure capable of assisting in medicine coating is mounted on the main bandage; the feeding structure comprises a feeding port, the feeding port is fixedly installed in the center of the lower surface of the main binding belt, the upper end of the feeding port is fixedly installed and communicated with a feeding pipe, the upper end of the feeding pipe extends to the outer portion of the main binding belt, and the upper end of the feeding pipe is fixedly connected and communicated with an injection pipe. A piston is movably installed in the injection pipe, in the use process, liquid medicine and lubricating grease are put into the injection pipe, a piston handle can drive the piston to push the liquid medicine and the lubricating grease into the feeding pipe, the liquid medicine and the lubricating grease flow into the massage assembly on the lower surface of the main bandage through the feeding opening, and the liquid medicine is smeared through the massage assembly in a moving mode.

Description

Technical Field

[0001] The present invention relates to the technical field of colorectal immunotherapy, and in particular to an in vivo individualized system immunotherapy device and method. Background Art

[0002] According to global cancer statistics released in 2020, colorectal cancer ranks third in cancer incidence and second in cancer mortality. In terms of gender, colorectal cancer is the second most common cause of cancer death in both men and women. According to forecasts, by 2030, the number of new cases of colorectal cancer will reach more than 2.2 million and the number of deaths will reach 1.1 million. Colorectal cancer usually occurs in the inner wall of the colon or rectum. According to histological classification, colon adenocarcinoma is the main type of colorectal cancer. The transformation of normal colon epithelium to colon adenocarcinoma is mainly due to genetic and epigenetic changes. Massage adjuvant therapy after immunotherapy also plays a key role in the recovery of the disease.

[0003] After searching, in the prior art, there is a device for enhancing the efficacy of pancreatic immunotherapy with the authorization publication number CN112516459B, which includes a main belt, a magnetic therapy belt, a heating control box, a massage block, an electric heating wire, a first belt, a belt hole, a second belt, a belt buckle and a temperature sensor. The outline of the main belt is rectangular, and three groups of equidistant and mutually parallel first belts are sewn on the left side of the main belt, and the three groups of the first belts are provided with belt holes distributed in a linear array. Three groups of equidistant and mutually parallel second belts are sewn on the right side of the main belt, and the second belts are riveted with belt buckles at one end facing away from the main belt. The first belt and the second belt are twisted and fixed with the main belt through Kevlar fiber lines. The edges of both ends of the main belt are provided with magnetic therapy belts on the side in contact with the patient's body, and the magnetic therapy belts are provided with six groups. The device for enhancing the efficacy of pancreatic immunotherapy can promote the effect of pancreatic immunotherapy and is suitable for universal promotion and use.

[0004] In the above technical solution, auxiliary treatment equipment is required to perform massage auxiliary treatment on the patient during immunotherapy. During this process, it is impossible for medical staff to apply liquid medicine to the part. For this reason, we propose an immunotherapy device and method of an in vivo personalized system. Summary of the invention

[0005] 1. Technical issues to be resolved

[0006] In view of the deficiencies in the prior art, the present invention provides an in vivo personalized system immunotherapy device and method, which solves the technical problem that auxiliary treatment equipment is needed to perform massage auxiliary treatment on patients during immunotherapy, and medical staff cannot assist in applying liquid medicine to the part during this process.

[0007] (II) Technical solution

[0008] To achieve the above objectives, the present invention is implemented through the following technical solutions: an in vivo individualized system immunotherapy device, comprising a main strap, a massage component is installed on the lower surface of the main strap, a magnetic therapy belt is installed on the lower surface of the main strap outside the massage component, and a feeding structure capable of assisting in coating a drug is installed on the main strap;

[0009] The feeding structure includes a feeding port, which is fixedly installed at the center of the lower surface of the main strap, and the upper end of the feeding port is fixedly installed and connected to a feeding pipe, the upper end of the feeding pipe extends to the outside of the main strap, the upper end of the feeding pipe is fixedly connected and connected to an injection pipe, a piston is movably installed inside the injection pipe, and the end of the piston is fixedly connected to a piston handle.

[0010] Preferably, a sealing plug is movably installed at the top of the feed port, a return spring is fixedly installed at the lower end of the sealing plug, a mounting ring is fixedly installed at the lower end of the return spring, the mounting ring is fixedly installed inside the feed port, and a plurality of feed grooves are opened on the inner wall of the feed port, and the upper end of each feed groove is arranged on the lower side of the sealing plug.

[0011] Preferably, an external thread is provided on the outer wall of the piston handle, and the piston handle is movably connected to the internal thread of the injection pipe via the external thread.

[0012] Preferably, the left and right ends of the main strap are respectively fixedly connected with a first fixing strap and a second fixing strap, the lower surface of the first fixing strap is provided with Velcro, the upper surface of the second fixing strap is provided with Velcro, and one end of the lower surface of the main strap is provided with an air inlet structure.

[0013] Preferably, the air inlet structure includes an air inlet, which is fixedly mounted on one end of the lower surface of the main strap, the upper end of the air inlet is fixedly mounted and connected to an air inlet pipe, the upper end of the air inlet pipe extends to the outside of the main strap, the upper end of the air inlet pipe is fixedly mounted and connected to an installation channel, and a fan is installed inside the installation channel.

[0014] Preferably, a seal is movably mounted on the inner top of the air inlet, a support spring is fixedly connected to the lower end of the seal, a spring frame is fixedly mounted on the lower end of the support spring, and the spring frame is fixedly mounted on the inner wall of the air inlet.

[0015] Preferably, a plurality of air inlet slots are provided on the inner wall of the air inlet, and the upper end of each of the air inlet slots is arranged on the lower side of the sealing member.

[0016] Preferably, an air outlet duct is installed on the lower surface of the main strap, and the air outlet duct is arranged at an end of the lower surface of the main strap away from the air inlet, and the upper end of the air outlet duct extends to the upper surface of the main strap.

[0017] Preferably, a first sealing column is fixedly installed at the bottom of the air outlet duct, and a second sealing column is rotatably connected to the upper side of the first sealing column inside the air outlet duct. The upper end of the second sealing column movably extends to the upper side of the air outlet duct and is fixedly connected to a handle. The first sealing column and the second sealing column are in contact with each other at one end and are movably connected. The outer walls of the first sealing column and the second sealing column are both penetrated from top to bottom with side openings, and the positions of the two side openings are correspondingly arranged. An air outlet is opened on the outer wall of the upper end of the first sealing column, and the air outlet is connected to the side opening, and the side opening is arranged outside the air outlet duct.

[0018] At the same time, the present invention also discloses a method of an in vivo individualized system immunotherapy device, comprising the following steps:

[0019] S1, wrapping the first fixing strap and the second fixing strap around the patient's body, and fixing the two straps with Velcro;

[0020] S2, putting the liquid medicine into the injection tube, the piston handle drives the piston to push the liquid medicine into the feed tube, and the liquid medicine flows into the massage component part on the lower surface of the main strap through the feed port;

[0021] S3, the massage component vibrates to massage the patient's body parts and vibrates to apply the medicine liquid on the patient's body surface.

[0022] (III) Beneficial effects

[0023] The present invention provides an in vivo individualized system immunotherapy device and method, which has the following beneficial effects:

[0024] During use, the medicine liquid and lubricating grease are put into the injection tube, and the piston handle can drive the piston to push the medicine liquid and lubricating grease into the feed tube, and flow into the massage component part on the lower surface of the main strap through the feed port, and the medicine liquid is moved and applied through the massage component.

[0025] When the vibration motor of the massage component is working, it drives the massage block to vibrate and move at the lower end of the vibration spring, thereby performing massage work, massaging the patient's body parts, and vibrating and coating the medicine liquid on the patient's body surface.

[0026] During use, the fan can send air into the air inlet pipe and the inside of the air inlet, and then enter the lower part of the main strap to contact the patient's skin. This can improve the dryness of the patient's body when the equipment is used, avoid excessive moisture and heat in the patient's body during use, and improve air circulation. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0028] Figure 2 It is a schematic diagram of the overall structure of the present invention when viewed from above;

[0029] Figure 3 This is a schematic diagram of the top view of the injection pipe of the present invention;

[0030] Figure 4 for Figure 3 Schematic diagram of the structure of the cross section at AA in FIG.

[0031] Figure 5 It is a structural schematic diagram of the air inlet pipe of the present invention;

[0032] Figure 6 for Figure 5 A schematic diagram of the structure of the cross section at BB in FIG.

[0033] Figure 7 It is a schematic diagram of the structure of the air outlet pipe of the present invention from a top view;

[0034] Figure 8 for Figure 7 Schematic diagram of the structure of the cross section at CC.

[0035] Among them, 1. main strap; 2. first fixed strap; 3. second fixed strap; 4. Velcro; 5. connecting line; 6. air inlet structure; 61. air inlet; 62. air inlet pipe; 63. installation channel; 64. fan; 65. spring frame; 66. support spring; 67. seal; 68. air inlet slot; 7. air outlet pipe; 71. first sealing column; 72. second sealing column; 73. side port; 74. air outlet; 75. handle; 8. feeding structure; 81. feeding port; 82. feeding pipe; 83. injection pipe; 84. piston; 85. piston handle; 86. external thread; 87. sealing plug; 88. feeding slot; 89. reset spring; 90. installation ring; 9. massage component; 10. magnetic therapy belt. DETAILED DESCRIPTION

[0036] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0037] Embodiment 1:

[0038] like Figure 1-Figure 8As shown, an embodiment of the present invention provides an in vivo individualized system immunotherapy device, including a main strap 1, a massage component 9 is installed on the lower surface of the main strap 1, the massage component 9 includes a groove set on the lower surface of the main strap 1, and a massage block movably installed in the groove, a vibration motor is installed on the top of the massage block, a vibration spring is fixedly installed on the top of the massage block outside the vibration motor, and the top of the vibration spring is fixed inside the groove. When the vibration motor is working, the massage block is driven to vibrate at the lower end of the vibration spring to perform massage, and a magnetic therapy belt 10 is installed on the lower surface of the main strap 1 outside the massage component 9. , the magnetic therapy belt 10 is installed on the lower surface of the main strap 1 along the periphery of the massage component 9, and a sealing ring is installed along the inner edge of the magnetic therapy belt 10, which can prevent the drug solution and air from flowing out through the gap between the skin and the main strap 1. The main strap 1 is installed with a feeding structure 8 that can assist in coating the drug. The main strap 1 is connected to the host through a connecting line 5. The magnetic therapy belt 10 is composed of a leather belt and a magnet. The magnets are distributed in a linear array. There are two groups of leather belts, which are located at the upper and lower ends of the magnets. The two groups of leather belts are connected by suturing with Kevlar thread. The magnetic therapy belt 10 plays a role in magnetic therapy to assist recovery;

[0039] The feeding structure 8 includes a feeding port 81, which is fixedly installed at the center of the lower surface of the main strap 1. The upper end of the feeding port 81 is fixedly installed and connected with a feeding pipe 82. The upper end of the feeding pipe 82 extends to the outside of the main strap 1. The upper end of the feeding pipe 82 is fixedly connected and connected with an injection pipe 83. A piston 84 is movably installed inside the injection pipe 83, and a piston handle 85 is fixedly connected to the end of the piston 84. During use, the medicine and lubricating grease are added to the injection pipe 83, and the piston handle 85 can drive the piston 84 to push the medicine and lubricating grease into the feeding pipe 82, and flow into the massage component 9 on the lower surface of the main strap 1 through the feeding port 81, and the medicine is moved and applied through the massage component 9.

[0040] In this embodiment, a sealing plug 87 is movably installed on the top of the feed port 81, a return spring 89 is fixedly installed on the lower end of the sealing plug 87, a mounting ring 90 is fixedly installed on the lower end of the return spring 89, and the mounting ring 90 is fixedly installed inside the feed port 81. A plurality of feed grooves 88 are opened on the inner wall of the feed port 81, and the upper end of each feed groove 88 is arranged on the lower side of the sealing plug 87. In use, the medicine liquid enters the feed port 81 through the feed pipe 82 and pushes the sealing plug 87 to move downward. When the sealing plug 87 moves to the lower side of the upper end opening of the feed groove 88, the medicine liquid flows through the feed groove 88 to the outside of the feed port 81 to complete the feeding work. When not entering, the return spring 89 can drive the sealing plug 87 to move and reset to the upper side of the feed groove 88, thereby cutting off the connection state of the feed port 81 and preventing the medicine liquid or air from flowing back.

[0041] In this embodiment, an external thread 86 is provided on the outer wall of the piston handle 85, and the piston handle 85 is movably connected to the internal thread of the injection tube 83 through the external thread 86. During use, by setting it as a threaded connection, the thread can be rotated to drive the piston handle 85 and the piston 84 to accurately control the moving distance and accurately control the amount of medicine released.

[0042] In this embodiment, the left and right ends of the main strap 1 are respectively fixedly connected with the first fixing strap 2 and the second fixing strap 3, the lower surface of the first fixing strap 2 is provided with Velcro 4, the upper surface of the second fixing strap 3 is provided with Velcro 4, and one end of the lower surface of the main strap 1 is provided with an air inlet structure 6. The first fixing strap 2 and the second fixing strap 3 are wrapped around the patient's body, and the two straps are adhered and fixed by Velcro 4.

[0043] In this embodiment, the air inlet structure 6 includes an air inlet 61, which is fixedly installed at one end of the lower surface of the main strap 1, and the upper end of the air inlet 61 is fixedly installed and connected to an air inlet pipe 62. The upper end of the air inlet pipe 62 extends to the outside of the main strap 1, and the upper end of the air inlet pipe 62 is fixedly installed and connected to a mounting channel 63. A fan 64 is installed inside the mounting channel 63. During use, air can be sent into the air inlet pipe 62 and the inside of the air inlet 61 through the fan 64, thereby entering the lower part of the main strap 1 and contacting the patient's skin, which can improve the dryness of the patient's body part when the equipment is used, avoid excessive moisture and heat in the patient's body part during use, and improve air circulation.

[0044] In this embodiment, a seal 67 is movably installed on the inner top of the air inlet 61, and a support spring 66 is fixedly connected to the lower end of the seal 67. A spring frame 65 is fixedly installed on the lower end of the support spring 66. The spring frame 65 is fixedly installed on the inner wall of the air inlet 61. A plurality of air inlet grooves 68 are opened on the inner wall of the air inlet 61. The upper end of each air inlet groove 68 is arranged on the lower side of the seal 67. In use, the air inlet pipe 62 enters the air inlet 61 and pushes the seal 67 to move downward. When the seal 67 moves to the lower side of the upper end opening of the air inlet groove 68, the air flows through the air inlet groove 68 to the outside of the air inlet 61 to complete the feeding work. In the non-air-inlet state, the support spring 66 can drive the seal 67 to move and reset to the upper side of the air inlet groove 68, thereby cutting off the connection state of the air inlet 61 and preventing the backflow of medicine or air.

[0045] In this embodiment, an air outlet pipe 7 is installed on the lower surface of the main strap 1. The air outlet pipe 7 is arranged at one end of the lower surface of the main strap 1 away from the air inlet 61. The upper end of the air outlet pipe 7 extends to the upper surface of the main strap 1. A first sealing column 71 is fixedly installed on the bottom of the air outlet pipe 7. A second sealing column 72 is rotatably connected to the upper side of the first sealing column 71 inside the air outlet pipe 7. The upper end of the second sealing column 72 movably extends to the upper side of the air outlet pipe 7 and is fixedly connected to a handle 75. The ends of the first sealing column 71 and the second sealing column 72 that are close to each other are in contact and movably connected. The outer ends of the first sealing column 71 and the second sealing column 72 are connected to each other. The wall is penetrated from top to bottom with side openings 73, and the positions of the two side openings 73 are set correspondingly. An air outlet 74 is opened on the outer wall of the upper end of the first sealing column 71, and the air outlet 74 is connected with the side opening 73. The side opening 73 is set outside the air outlet pipe 7. During use, the handle 75 and the second sealing column 72 are rotated to make the two side openings 73 located on the first sealing column 71 and the second sealing column 72 in a connected state, so that the air is discharged through the two side openings 73 and the air outlet 74. In the non-connected state, the two side openings 73 are offset to disconnect the internal connection state of the air outlet pipe 7, which can prevent air and liquid medicine from flowing out.

[0046] At the same time, the present invention also discloses a method of an in vivo individualized system immunotherapy device, comprising the following steps:

[0047] S1, using a first fixing strap 2 and a second fixing strap 3 to wrap around the patient's body, and fixing the two straps with Velcro 4;

[0048] S2, the liquid medicine is put into the injection tube 83, the piston handle 85 drives the piston 84 to push the liquid medicine into the feed tube 82, and flows into the massage component 9 on the lower surface of the main strap 1 through the feed port 81;

[0049] S3, the massage component 9 vibrates to massage the patient's body parts and applies the medicine liquid to the patient's body surface through vibration.

[0050] Working principle:

[0051] During use, the medicine liquid and lubricating grease are put into the injection tube 83, and the piston handle 85 can drive the piston 84 to push the medicine liquid and lubricating grease into the feed tube 82, and flow into the massage component 9 on the lower surface of the main strap 1 through the feed port 81, and the medicine liquid is moved and applied through the massage component 9.

[0052] When the vibration motor of the massage component 9 is working, it drives the massage block to vibrate and move at the lower end of the vibration spring, thereby performing massage work, massaging the patient's body parts, and vibrating and coating the medicine liquid on the patient's body surface.

[0053] During use, the air can be sent into the air inlet pipe 62 and the air inlet 61 through the fan 64, and then enter the lower part of the main strap 1 to contact the patient's skin, which can improve the dryness of the patient's body when the equipment is used, avoid excessive moisture and heat in the patient's body during use, and improve air circulation.

[0054] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not limitations on the implementation modes of the present invention. For ordinary technicians in the relevant field, other different forms of changes or modifications can be made on the basis of the above description. It is impossible to list all the implementation modes here. All obvious changes or modifications derived from the technical solution of the present invention are still within the protection scope of the present invention.

Claims

1. An in vivo individualized system immunotherapy device, comprising a main strap (1), characterized in that: A massage component (9) is installed on the lower surface of the main strap (1); a magnetic therapy belt (10) is installed on the lower surface of the main strap (1) outside the massage component (9); and a feeding structure (8) capable of assisting in coating a drug is installed on the main strap (1); The feed structure (8) comprises a feed port (81), the feed port (81) is fixedly mounted at the center of the lower surface of the main strap (1), the upper end of the feed port (81) is fixedly mounted and connected to a feed pipe (82), the upper end of the feed pipe (82) extends to the outside of the main strap (1), the upper end of the feed pipe (82) is fixedly connected and connected to an injection pipe (83), a piston (84) is movably mounted inside the injection pipe (83), and the end of the piston (84) is fixedly connected to a piston handle (85).

2. The immunotherapy device of the in vivo personalized system according to claim 1, characterized in that: A sealing plug (87) is movably installed at the top of the feed port (81), a return spring (89) is fixedly installed at the lower end of the sealing plug (87), a mounting ring (90) is fixedly installed at the lower end of the return spring (89), and the mounting ring (90) is fixedly installed inside the feed port (81). A plurality of feed grooves (88) are provided on the inner wall of the feed port (81), and the upper end of each of the feed grooves (88) is arranged on the lower side of the sealing plug (87).

3. The immunotherapy device of the in vivo personalized system according to claim 2, characterized in that: An external thread (86) is provided on the outer wall of the piston handle (85), and the piston handle (85) is movably connected to the internal thread of the injection pipe (83) via the external thread (86).

4. The immunotherapy device of the in vivo personalized system according to claim 1, characterized in that: The left and right ends of the main strap (1) are respectively fixedly connected to a first fixing strap (2) and a second fixing strap (3); the lower surface of the first fixing strap (2) is provided with a Velcro (4); the upper surface of the second fixing strap (3) is provided with a Velcro (4); and one end of the lower surface of the main strap (1) is provided with an air inlet structure (6).

5. The immunotherapy device of the in vivo personalized system according to claim 4, characterized in that: The air inlet structure (6) comprises an air inlet (61), the air inlet (61) is fixedly mounted on one end of the lower surface of the main binding belt (1), the upper end of the air inlet (61) is fixedly mounted and connected to an air inlet pipe (62), the upper end of the air inlet pipe (62) extends to the outside of the main binding belt (1), the upper end of the air inlet pipe (62) is fixedly mounted and connected to an installation channel (63), and a fan (64) is installed inside the installation channel (63).

6. The immunotherapy device of the in vivo personalized system according to claim 5, characterized in that: A sealing member (67) is movably mounted on the inner top of the air inlet (61); a support spring (66) is fixedly connected to the lower end of the sealing member (67); a spring frame (65) is fixedly mounted on the lower end of the support spring (66); and the spring frame (65) is fixedly mounted on the inner wall of the air inlet (61).

7. The immunotherapy device of the in vivo personalized system according to claim 6, characterized in that: A plurality of air inlet grooves (68) are provided on the inner wall of the air inlet (61), and the upper end of each of the air inlet grooves (68) is arranged on the lower side of the sealing member (67).

8. The immunotherapy device of the in vivo personalized system according to claim 5, characterized in that: An air outlet pipe (7) is installed on the lower surface of the main binding belt (1), and the air outlet pipe (7) is arranged at an end of the lower surface of the main binding belt (1) away from the air inlet (61), and the upper end of the air outlet pipe (7) extends to the upper surface of the main binding belt (1).

9. The immunotherapy device of the in vivo personalized system according to claim 8, characterized in that: A first sealing column (71) is fixedly installed at the bottom of the air outlet pipe (7); a second sealing column (72) is rotatably connected to the upper side of the first sealing column (71) inside the air outlet pipe (7); the upper end of the second sealing column (72) movably extends to the upper side of the air outlet pipe (7) and is fixedly connected to a handle (75); the first sealing column (71) and the second sealing column (72) are in contact with each other at one end and are movably connected; the outer walls of the first sealing column (71) and the second sealing column (72) are both penetrated from top to bottom with side openings (73); the positions of the two side openings (73) are correspondingly arranged; an air outlet (74) is arranged on the outer wall of the upper end of the first sealing column (71); the air outlet (74) is connected to the side opening (73); and the side opening (73) is arranged outside the air outlet pipe (7).

10. The method of an in vivo personalized system immunotherapy device according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1, using the first fixing strap (2) and the second fixing strap (3) to wrap around the patient's body, and fixing the two straps by Velcro (4); S2, injecting the liquid medicine into the injection tube (83), the piston handle (85) drives the piston (84) to push the liquid medicine into the feed tube (82), and flows into the massage component (9) on the lower surface of the main strap (1) through the feed port (81); S3, the massage component (9) vibrates to massage the patient's body parts and applies the medicine liquid to the surface of the patient's body through vibration.

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