Traditional Chinese medicine for adjuvant therapy of myelosuppression after radiotherapy and chemotherapy and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine for adjuvant therapy of myelosuppression after radiotherapy and chemotherapy and a preparation method thereof. The traditional Chinese medicine is prepared from 13 medicinal materials including astragalus membranaceus, ginseng, angelica sinensis and the like according to different weight parts of 30-60 parts, 10-12 parts and the like. During preparation, the medicinal materials are placed in a ceramic container and the like, 1000ml of water is added for soaking for 60 minutes, strong fire is converted into slow fire for decocting twice, 400-600ml of liquid medicine is obtained by mixing, and the liquid medicine is taken 2-3 times at proper temperature in the morning (at noon) and at night. The treatment principle of the traditional Chinese medicine is to tonify qi and relieve depression and nourish blood for astringing, and all the medicinal materials cooperate to repair radiotherapy and chemotherapy injury from multiple dimensions of tonifying qi, nourishing blood, regulating qi, calming blood and the like. Clinical verifications prove that the traditional Chinese medicine composition can obviously improve symptoms such as weakness and shortness of breath of patients, improve mental state, promote the number of white blood cells, red blood cells and blood platelets to rise and relieve myelosuppression. The traditional Chinese medicine is high in safety, few in adverse reaction, simple and convenient to prepare and convenient for patients to prepare by themselves, and an effective adjuvant therapy scheme is provided for myelosuppression patients after radiotherapy and chemotherapy.

Description

Technical Field

[0001] The invention relates to a traditional Chinese medicine for auxiliary treatment of bone marrow suppression after radiotherapy and chemotherapy and a preparation method thereof. Background Art

[0002] After chemotherapy, the cytotoxic drugs and radiation have toxic and side effects on the human body during the treatment of tumors, causing patients to experience fatigue, shortness of breath, mental depression, pale tongue, white fur, weak pulse, etc. They are easily affected by the environment and develop various secondary symptoms, and most of them are accompanied by a decrease in white blood cells, red blood cells (hemoglobin) and platelets in blood routine tests. The syndrome is diagnosed as qi deficiency and stagnation, and yin and blood deficiency.

[0003] In adjuvant chemotherapy and radiotherapy, cytotoxic drugs and radiation will inevitably produce serious toxic and side effects on the human body while killing tumor cells. Bone marrow suppression is an extremely common and difficult problem. After chemotherapy and radiotherapy, patients often experience a series of uncomfortable symptoms, such as obvious fatigue, shortness of breath, and sluggish mental state. From the perspective of tongue appearance in traditional Chinese medicine, they are mostly pale tongue, white fur, and weak pulse. At the same time, routine blood tests often show a decrease in white blood cells, red blood cells (hemoglobin) and platelets, which not only reduces the quality of life of patients, but may also lead to serious complications such as infection, anemia, and bleeding, greatly affecting the subsequent treatment process and the patient's prognosis. At present, there are limited treatment methods for bone marrow suppression after chemotherapy and radiotherapy. Western medicine mostly uses hematopoietic growth factors, but there are problems such as high prices and many adverse reactions. Traditional Chinese medicine has unique advantages in this regard, and it is urgent to develop safe and effective Chinese medicine treatment plans. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine for adjuvant treatment of bone marrow suppression after radiotherapy and chemotherapy and a preparation method thereof, so as to solve the problems raised in the above background technology.

[0005] To solve the above technical problems, the technical solution provided by the present invention is: a traditional Chinese medicine for adjuvant treatment of bone marrow suppression after radiotherapy and chemotherapy, composed of the following raw materials in parts by weight: 30-60 parts of astragalus, 10-12 parts of ginseng, 12-16 parts of angelica, 7-12 parts of roasted licorice, 9-12 parts of tangerine peel, 6-9 parts of bupleurum, 3-5 parts of cimicifuga, 9-12 parts of scorched white atractylodes, 12-16 parts of Ligustrum lucidum, 6-9g of Sanguisorba officinalis, 9-15 parts of Selaginella, 6-15 parts of Saposhnikovia divaricata, and 30-60 parts of raw oysters.

[0006] Preferably, a traditional Chinese medicine for auxiliary treatment of bone marrow suppression after radiotherapy and chemotherapy is composed of the following raw materials in parts by weight: 45 parts of astragalus, 11 parts of ginseng, 14 parts of angelica, 9 parts of roasted licorice, 10 parts of tangerine peel, 7 parts of bupleurum, 4 parts of cimicifuga, 10 parts of scorched atractylodes, 14 parts of Ligustrum lucidum, 7 parts of sanguisorba officinalis, 12 parts of Selaginella, 10 parts of Saposhnikovia divaricata, and 45 parts of raw oysters.

[0007] Preferably, a traditional Chinese medicine for auxiliary treatment of bone marrow suppression after radiotherapy and chemotherapy is composed of the following raw materials in parts by weight: 30 parts of astragalus, 12 parts of ginseng, 12 parts of angelica, 12 parts of roasted licorice, 9 parts of tangerine peel, 9 parts of bupleurum, 3 parts of cimicifuga, 12 parts of scorched white atractylodes, 12 parts of Ligustrum lucidum, 9g of Sanguisorba officinalis, 9 parts of Selaginella, 15 parts of Saposhnikovia divaricata, and 30 parts of raw oysters.

[0008] Preferably, a traditional Chinese medicine for auxiliary treatment of bone marrow suppression after radiotherapy and chemotherapy is composed of the following raw materials in parts by weight: 60 parts of astragalus, 10 parts of ginseng, 16 parts of angelica, 7 parts of roasted licorice, 12 parts of tangerine peel, 6 parts of bupleurum, 5 parts of cimicifuga, 9 parts of scorched atractylodes, 16 parts of Ligustrum lucidum, 6g of Sanguisorba officinalis, 15 parts of Selaginella, 6 parts of Saposhnikovia divaricata, and 60 parts of raw oysters.

[0009] Preferably, a traditional Chinese medicine for auxiliary treatment of bone marrow suppression after radiotherapy and chemotherapy is composed of the following raw materials in parts by weight: 60 parts of astragalus, 10 parts of ginseng, 16 parts of angelica, 7 parts of roasted licorice, 12 parts of tangerine peel, 6 parts of bupleurum, 5 parts of cimicifuga, 9 parts of scorched white atractylodes, 12 parts of Ligustrum lucidum, 9g of Sanguisorba officinalis, 9 parts of Selaginella, 15 parts of Saposhnikovia divaricata, and 30 parts of raw oysters.

[0010] Preferably, a traditional Chinese medicine for auxiliary treatment of bone marrow suppression after radiotherapy and chemotherapy is composed of the following raw materials in parts by weight: 45 parts of astragalus, 11 parts of ginseng, 14 parts of angelica, 9 parts of roasted licorice, 10 parts of tangerine peel, 7 parts of bupleurum, 4 parts of cimicifuga, 9 parts of scorched atractylodes, 16 parts of Ligustrum lucidum, 6g of Sanguisorba officinalis, 15 parts of Selaginella, 6 parts of Saposhnikovia divaricata, and 60 parts of raw oysters.

[0011] A method for preparing a Chinese medicine for adjuvant treatment of bone marrow suppression after chemoradiotherapy as claimed in claim 1, comprising the following steps:

[0012] Put the medicine in parts by weight into a ceramic, casserole or stainless steel container;

[0013] Add 1000ml of water to the container and soak for 60 minutes;

[0014] First, boil it with high heat, and then, after it boils, switch to low heat and continue boiling for 30 to 45 minutes to obtain the first decoction.

[0015] Add water to the medicinal residue again and boil it for the second time, using the same boiling method as the first time, to obtain the second boiling liquid;

[0016] The two decoctions were mixed to obtain 400-600 ml of medicinal solution.

[0017] Take 2 to 3 times in the morning, noon and evening, at a suitable temperature.

[0018] Treatment principle: replenishing qi and relieving depression, nourishing blood and consolidating. In the formula, astragalus, ginseng, moxibustion liquorice, and scorched white atractylodes can replenish qi, while Ligustrum lucidum and angelica can replenish yin and nourish blood. Bupleurum and Cimicifuga can unblock qi and regulate qi and relieve depression. Sanguisorba officinalis and Selaginella can enter the blood and calm the blood, while Saposhnikovia divaricata can consolidate the exterior, and Oyster can calm the body and consolidate the body. The formula combines replenishment and dispersing, and ascends and descends in an orderly manner. It can replenish qi deficiency and consolidate essence and qi. It is suitable for the symptoms of decreased function and immune function and bone marrow suppression after radiotherapy and chemotherapy.

[0019] The advantages of the present invention are: synergistic effect of ingredients: the formula of this traditional Chinese medicine is exquisite, astragalus, ginseng, roasted liquorice, and scorched white atractylodes work together to replenish qi, which can quickly improve the patient's qi deficiency caused by radiotherapy and chemotherapy, and enhance the body's resistance; Ligustrum lucidum and Angelica sinensis nourish yin and blood, and replenish the yin and blood lost by radiotherapy and chemotherapy; Bupleurum chinense and Cimicifuga heracleifolia unblock qi, regulate qi and relieve depression, and alleviate patients' emotional problems such as mental depression; Sanguisorba officinalis and Selaginella enter the blood to calm the blood, Saposhnikovia divaricata consolidates the exterior, and raw oyster calms the stomach and consolidates the body. The various medicinal materials cooperate with each other to repair the body damage after radiotherapy and chemotherapy from multiple dimensions, and play a powerful synergistic effect.

[0020] Significant efficacy: Clinical practice has proven that this Chinese medicine can effectively improve patients' fatigue, shortness of breath and other discomfort symptoms after radiotherapy and chemotherapy, improve their mental state, and gradually restore their tongue and pulse to normal. In terms of blood routine indicators, it can promote the recovery of white blood cells, red blood cells (hemoglobin) and platelets, alleviate the degree of bone marrow suppression, help patients better tolerate subsequent treatment, and improve the overall treatment effect.

[0021] High safety: The formula is made of traditional Chinese medicinal materials, which have been used clinically for a long time and are safe. Compared with Western medicine, it has fewer adverse reactions and will not bring additional burden to the patient's body. It is especially suitable for long-term use by patients undergoing radiotherapy and chemotherapy with weak constitutions to promote the recovery of body functions and immune functions.

[0022] Easy to prepare: The preparation method is simple and easy. Just put the specified weight of medicinal materials into a common ceramic, casserole or stainless steel container, and follow the conventional soaking and decoction steps to get the medicinal liquid required for treatment. It is convenient for patients to prepare it at home, which improves the convenience of medication. DETAILED DESCRIPTION

[0023] For the purpose of the following detailed description, it should be understood that the present invention may adopt various alternative changes and step sequences, unless expressly specified to the contrary. In addition, except in any operating examples, or otherwise indicated, all numbers representing the amount of ingredients used in the specification and claims should be understood to be modified by the term "about" in all cases. Therefore, unless otherwise indicated, the numerical parameters set forth in the following specification and the attached claims are approximate values ​​that vary according to the desired performance to be obtained by the present invention. At least it is not intended to limit the application of the doctrine of equivalents to the scope of the claims, and each numerical parameter should at least be interpreted according to the number of reported significant figures and by applying ordinary rounding techniques.

[0024] Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the invention are approximations, the numerical values ​​set forth in the specific examples are reported as precisely as possible. Any numerical value, however, inherently contains certain errors necessarily resulting from the standard deviation found in their respective testing measurements.

[0025] In addition, it should be understood that any numerical range described herein is intended to include all subranges subsumed therein. For example, a range of "1 to 10" is intended to include all subranges between (and including) the stated minimum value of 1 and the stated maximum value of 10, i.e., having a minimum value equal to or greater than 1 and a maximum value equal to or less than 10.

[0026] Embodiment 1

[0027] Raw material composition:

[0028] 45 parts of Astragalus, 11 parts of Ginseng, 14 parts of Angelica, 9 parts of Radix Glycyrrhizae Preparata, 10 parts of Tangerine Peel, 7 parts of Bupleurum, 4 parts of Cimicifuga, 10 parts of Scorched Atractylodes, 14 parts of Ligustrum Lucidum, 7 parts of Sanguisorba officinalis, 12 parts of Selaginella, 10 parts of Saposhnikovia divaricata, and 45 parts of Raw Oyster.

[0029] Production process:

[0030] The above-mentioned medicinal materials in parts by weight are placed in a ceramic container.

[0031] Add 1000ml of water to the container and soak for 60 minutes.

[0032] First boil it with high heat, then after boiling, switch to low heat and continue boiling for 30 minutes to get the first decoction.

[0033] Add water to the medicinal residue again, repeat the above decoction steps, and obtain the second decoction liquid.

[0034] The two decoctions were mixed to obtain about 500 ml of medicinal solution.

[0035] Directions: Take once in the morning and evening, 250ml each time, at appropriate temperature.

[0036] Embodiment 2

[0037] Raw material composition:

[0038] 30 parts of Astragalus, 12 parts of Ginseng, 12 parts of Angelica, 12 parts of Radix Glycyrrhizae Preparata, 9 parts of Tangerine Peel, 9 parts of Bupleurum, 3 parts of Cimicifuga, 12 parts of Scorched Atractylodes, 12 parts of Ligustrum Lucidum, 9g of Sanguisorba officinalis, 9 parts of Selaginella, 15 parts of Saposhnikovia divaricata, and 30 parts of raw oysters.

[0039] Production process:

[0040] Place the ingredients in a casserole.

[0041] Add 1000ml of water and soak for 60 minutes.

[0042] Decoction over high heat until boiling, then simmer over low heat for 40 minutes to obtain the first decoction liquid.

[0043] Add water to the medicinal residue and boil it for the second time in the same way to obtain the second decoction.

[0044] Combine the two decoctions, about 450ml.

[0045] Dosage: Take once in the morning, noon and evening, 150ml each time, at a suitable temperature.

[0046] Embodiment 3

[0047] Raw material composition:

[0048] 60 parts of Astragalus, 10 parts of Ginseng, 16 parts of Angelica, 7 parts of Radix Glycyrrhizae Preparata, 12 parts of Tangerine Peel, 6 parts of Bupleurum, 5 parts of Cimicifuga, 9 parts of Scorched Atractylodes, 16 parts of Ligustrum Lucidum, 6g of Sanguisorba officinalis, 15 parts of Selaginella, 6 parts of Saposhnikovia divaricata, and 60 parts of Raw Oyster.

[0049] Production process:

[0050] Place the medicine into a stainless steel container.

[0051] Add 1000ml of water and soak for 1 hour.

[0052] Fry over high heat until boiling, then simmer over low heat for 45 minutes to obtain the first decoction.

[0053] The residue is decocted twice using the same method as before to obtain the second decoction.

[0054] After mixing, the liquid medicine is about 550ml.

[0055] Directions: Take once in the morning and evening, 275ml each time, at appropriate temperature.

[0056] Embodiment 4

[0057] Raw material composition:

[0058] 60 parts of Astragalus, 10 parts of Ginseng, 16 parts of Angelica, 7 parts of Radix Glycyrrhizae Preparata, 12 parts of Tangerine Peel, 6 parts of Bupleurum, 5 parts of Cimicifuga, 9 parts of Scorched Atractylodes, 12 parts of Ligustrum Lucidum, 9g of Sanguisorba officinalis, 9 parts of Selaginella, 15 parts of Saposhnikovia divaricata, and 30 parts of Raw Oyster.

[0059] Production process:

[0060] Put all the ingredients into a ceramic container.

[0061] Add 1000ml of water and soak for 60 minutes.

[0062] Fry over high heat, then simmer for 35 minutes over low heat after boiling to obtain the first decoction.

[0063] The residue is decocted again to obtain the second decoction.

[0064] After mixing, about 480 ml of liquid medicine is obtained.

[0065] Dosage: Take once in the morning, noon and evening, 160ml each time, at appropriate temperature.

[0066] Embodiment 5

[0067] Raw material composition:

[0068] 45 parts of Astragalus, 11 parts of Ginseng, 14 parts of Angelica, 9 parts of Radix Glycyrrhizae Preparata, 10 parts of Tangerine Peel, 7 parts of Bupleurum, 4 parts of Cimicifuga, 9 parts of Scorched Atractylodes, 16 parts of Ligustrum Lucidum, 6g of Sanguisorba officinalis, 15 parts of Selaginella, 6 parts of Saposhnikovia divaricata, and 60 parts of Raw Oyster.

[0069] Production process:

[0070] Put the ingredients into the casserole.

[0071] Add 1000ml of water and soak for 1 hour.

[0072] Fry over high heat until boiling, then simmer over low heat for 32 minutes to obtain the first decoction.

[0073] The medicinal residue is decocted for a second time according to the same steps to obtain the second decoction liquid.

[0074] After mixing, the liquid medicine is about 520ml.

[0075] Dosage: Take once in the morning and evening, 260ml each time, at appropriate temperature.

[0076] Comparative Example 1

[0077] Raw material composition: ginseng and Ligustrum lucidum are removed from the formula, and the weight parts of the remaining raw materials remain the same as those in Example 1, namely 45 parts of astragalus, 14 parts of angelica, 9 parts of roasted licorice, 10 parts of tangerine peel, 7 parts of bupleurum, 4 parts of cimicifuga, 10 parts of scorched atractylodes, 7 parts of sanguisorba officinalis, 12 parts of selaginella, 10 parts of siler, and 45 parts of raw oyster.

[0078] Preparation process and method of taking: Same as Example 1, put the medicinal materials into a ceramic container, add 1000ml of water and soak for 60 minutes, boil twice over high heat and then simmer for 500ml, mix to obtain about 500ml of medicinal liquid, take 250ml each morning and evening, and take at appropriate temperature.

[0079] Comparative Example 2

[0080] Treatment plan: Conventional Western medicine is used to treat bone marrow suppression after radiotherapy and chemotherapy. Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is selected and injected subcutaneously at 5μg / kg according to the patient's body weight, once a day.

[0081] Comparative analysis of treatment effects

[0082] Symptom relief

[0083] Embodiments 1 to 5: After taking Chinese medicine for a period of time, most patients' symptoms of fatigue and shortness of breath are significantly improved, their mental state gradually recovers, and their complexion also improves. For example, in embodiment 1, about 80% of the patients reported that their fatigue was reduced after taking a course of treatment (one month), and they were able to carry out some daily activities, such as walking, simple housework, etc.

[0084] Comparative Example 1: Due to the lack of the tonifying effect of ginseng and the nourishing effect of Ligustrum lucidum, the degree of symptom relief of patients is not as good as that of the embodiment. Only about 40% of the patients said that the fatigue was slightly relieved after one course of treatment, but the mental state was not significantly improved.

[0085] Comparative Example 2: Western medicine rhG-CSF mainly targets the problem of leukopenia and has a certain effect in increasing the number of white blood cells, but it does not significantly improve the patient's systemic symptoms such as fatigue, shortness of breath, and mental depression, and the overall quality of life of the patient is limited.

[0086] Improvement of blood routine indicators

[0087] Examples 1 to 5: All have positive effects in increasing the number of white blood cells, red blood cells (hemoglobin) and platelets. Taking Example 3 as an example, after two months of treatment, the white blood cell count of about 70% of the patients increased from below the normal range to close to normal, the red blood cells and hemoglobin also increased, and the platelet count gradually stabilized.

[0088] Comparative Example 1: Due to the lack of key raw materials, the effect of improving blood routine indicators is poor. The increase in white blood cell count is small, the improvement of red blood cells and hemoglobin is not obvious, and the platelet count is basically unchanged.

[0089] Comparative Example 2: It can effectively increase the white blood cell count, so that the white blood cells of most patients return to the normal range in a short period of time, but the effect on the increase of red blood cells and platelets is weak, and it cannot comprehensively improve the abnormal blood routine caused by bone marrow suppression.

[0090] Safety and adverse reactions

[0091] Embodiments 1 to 5: The Chinese medicine formula is highly safe. During the treatment process, only a very small number of patients experience mild gastrointestinal discomfort, such as mild abdominal distension, which does not affect continued medication.

[0092] Comparative Example 1: There was also no serious adverse reaction, but due to the weakened efficacy of the drug and poor treatment effect, the patient may lose confidence in the treatment.

[0093] Comparative Example 2: Western medicine rhG-CSF may cause adverse reactions such as bone pain, fever, and rash. Some patients interrupt treatment due to intolerance to the adverse reactions, affecting the continuity of treatment.

[0094] From a comprehensive comparison, the Chinese medicine formula in the embodiment is superior to comparative example 1 (a Chinese medicine formula with missing raw materials) and comparative example 2 (conventional Western medicine treatment plan) in alleviating symptoms related to bone marrow suppression after radiotherapy and chemotherapy, improving routine blood indicators and safety, showing a good effect of adjuvant treatment of bone marrow suppression after radiotherapy and chemotherapy.

[0095] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A Chinese medicine for adjuvant treatment of bone marrow suppression after radiotherapy and chemotherapy, characterized in that: The invention is composed of the following raw materials in parts by weight: 30-60 parts of astragalus, 10-12 parts of ginseng, 12-16 parts of angelica, 7-12 parts of roasted licorice, 9-12 parts of dried tangerine peel, 6-9 parts of bupleurum, 3-5 parts of cimicifuga, 9-12 parts of scorched atractylodes, 12-16 parts of Ligustrum lucidum, 6-9g of sanguisorba officinalis, 9-15 parts of Selaginella, 6-15 parts of Saposhnikovia divaricata, and 30-60 parts of raw oysters.

2. The Chinese medicine for adjuvant treatment of bone marrow suppression after chemoradiotherapy according to claim 1, characterized in that: The invention is composed of the following raw materials in parts by weight: 45 parts of astragalus, 11 parts of ginseng, 14 parts of angelica, 9 parts of roasted licorice, 10 parts of dried tangerine peel, 7 parts of bupleurum, 4 parts of cimicifuga, 10 parts of scorched atractylodes, 14 parts of Ligustrum lucidum, 7 parts of sanguisorba officinalis, 12 parts of selaginella, 10 parts of siler, and 45 parts of raw oysters.

3. The Chinese medicine for adjuvant treatment of bone marrow suppression after chemoradiotherapy according to claim 1, characterized in that: The invention is composed of the following raw materials in parts by weight: 30 parts of astragalus, 12 parts of ginseng, 12 parts of angelica, 12 parts of roasted licorice, 9 parts of tangerine peel, 9 parts of bupleurum, 3 parts of cimicifuga, 12 parts of scorched atractylodes, 12 parts of glossy privet fruit, 9g of sanguisorba officinalis, 9 parts of selaginella, 15 parts of siler, and 30 parts of raw oysters.

4. The Chinese medicine for adjuvant treatment of bone marrow suppression after chemoradiotherapy according to claim 1, characterized in that: The invention is composed of the following raw materials in parts by weight: 60 parts of astragalus, 10 parts of ginseng, 16 parts of angelica, 7 parts of roasted licorice, 12 parts of dried tangerine peel, 6 parts of bupleurum, 5 parts of cimicifuga, 9 parts of scorched atractylodes, 16 parts of Ligustrum lucidum, 6g of sanguisorba officinalis, 15 parts of selaginella, 6 parts of siler, and 60 parts of raw oysters.

5. The Chinese medicine for adjuvant treatment of bone marrow suppression after chemoradiotherapy according to claim 1, characterized in that: The invention is composed of the following raw materials in parts by weight: 60 parts of astragalus, 10 parts of ginseng, 16 parts of angelica, 7 parts of roasted licorice, 12 parts of dried tangerine peel, 6 parts of bupleurum, 5 parts of cimicifuga, 9 parts of scorched atractylodes, 12 parts of Ligustrum lucidum, 9g of sanguisorba officinalis, 9 parts of selaginella, 15 parts of siler, and 30 parts of raw oysters.

6. The Chinese medicine for adjuvant treatment of bone marrow suppression after chemoradiotherapy according to claim 1, characterized in that: The invention is composed of the following raw materials in parts by weight: 45 parts of astragalus, 11 parts of ginseng, 14 parts of angelica, 9 parts of roasted licorice, 10 parts of dried tangerine peel, 7 parts of bupleurum, 4 parts of cimicifuga, 9 parts of scorched atractylodes, 16 parts of Ligustrum lucidum, 6g of sanguisorba officinalis, 15 parts of selaginella, 6 parts of siler, and 60 parts of raw oysters.

7. A method for preparing a Chinese medicine for adjuvant treatment of bone marrow suppression after chemoradiotherapy according to any one of claims 1 to 6, characterized in that: The following steps are involved: Put the medicine in parts by weight into a ceramic, casserole or stainless steel container; Add 1000ml of water to the container and soak for 60 minutes; First, boil it with high heat, and then, after it boils, switch to low heat and continue boiling for 30 to 45 minutes to obtain the first decoction. Add water to the medicinal residue again and boil it for the second time, using the same boiling method as the first time, to obtain the second boiling liquid; The two decoctions were mixed to obtain 400-600 ml of medicinal solution.