Biotechnology reagent refrigeration and transfer device and method

Abstract

The invention belongs to the field of biotechnology, and particularly discloses a reagent refrigerating and transferring device and method for biotechnology, and the reagent refrigerating and transferring device comprises a refrigerating box, a placing mechanism and a heat preservation mechanism; the placing mechanism comprises a placing box movably arranged in the refrigerating box, a plurality of elastic frames are movably arranged in the placing box, and brackets are fixedly mounted at the bottoms of the elastic frames; when the placing box needs to be pulled out for taking out a test tube or putting in a new test tube, a threaded rod is rotated, the threaded rod can drive a movable shell to move front and back until a first through groove and a second through groove are staggered, the inner space and the outer space of the placing box are separated, and it is avoided that when the placing box is pulled out, the test tube is taken out or a new test tube is put in. Cold air in the refrigerating box drifts to the external environment through the first through groove, the situation that the follow-up refrigerating performance of the refrigerating box is reduced due to loss of the cold air is effectively avoided, meanwhile, the situation that the cold air blows to a user to cause frostbite and discomfort is avoided, and people can use the refrigerating box conveniently.

Description

Technical Field

[0001] The present invention belongs to the field of biotechnology, and in particular relates to a device and method for refrigerating and transporting reagents for biotechnology. Background Art

[0002] In modern biotechnology and pharmaceutical industries, many reagents (such as biological samples, antibodies, enzymes, etc.) are extremely sensitive to temperature and must be stored and transported within a specific temperature range. Therefore, refrigerated transport devices are required for the transportation of biological reagents.

[0003] However, traditional refrigerated transport devices need to be fully opened when biological reagents need to be placed or removed. At this time, the cold air in the device will quickly lose, affecting the subsequent refrigeration effect. At the same time, the cold air will directly affect the user, causing frostbite and discomfort, which is not conducive to personnel use. Summary of the invention

[0004] The purpose of the present invention is to provide a biotechnology reagent refrigeration and transportation device and method to solve the problem in the above-mentioned background technology that when the biological reagent needs to be placed or taken out, the device needs to be fully opened, and the cold air in the device will be lost quickly, affecting the subsequent refrigeration effect.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A refrigerated transport device for reagents used in biotechnology, comprising a cold storage box, a placement mechanism and a heat preservation mechanism; the placement mechanism comprises a placement box movably arranged in the cold storage box, a plurality of elastic frames movably arranged in the placement box, and a bracket is fixedly installed at the bottom of the elastic frame; the heat preservation mechanism comprises a plurality of through slots 1 arranged at the top and bottom of the placement box, a movable shell movably arranged in the placement box, a plurality of through slots 2 arranged at the top and bottom of the movable shell, the through slots 1 and 2 being matched, movable blocks are fixedly installed on both sides of the movable shell, a threaded rod is movably arranged on the placement box, and the threaded rod is threadedly connected to the movable block.

[0007] Preferably, slide bars are fixedly installed inside the refrigerators on both sides of the placement box, and an insulation plate is slidably arranged between the slide bars at the other end of the placement box.

[0008] Preferably, magnetic blocks are fixedly mounted on the rear end surface of the placement box and the front end surfaces of the insulation boards on both sides of the placement box.

[0009] Preferably, the reagent refrigeration and transport device also includes a cache mechanism, which includes a movable frame movably arranged between the placement box and the elastic frame, movable seats are fixedly installed at both ends of the movable frame, racks are arranged on both sides of the movable seat, and a gear is arranged at the internal front end of the placement box, and the gear is meshed with the rack.

[0010] Preferably, both ends of the placement box are provided with slide rails, and the slide rails are slidably connected to the movable seat.

[0011] Preferably, the front ends of the gear and the threaded rod penetrate through a placement box and are provided with rotating wheels, and a handle is fixedly provided at the front end of the placement box.

[0012] Preferably, a bearing is installed between the elastic frame and the movable frame, a fixed block is fixedly installed on the elastic frame, and a stopper is fixedly installed on the movable frame on the rotational movement path of the fixed block.

[0013] Preferably, a connecting rod is movably installed between the brackets of several of the elastic racks.

[0014] A method for refrigerating and transporting a biotech reagent, using the above-mentioned refrigerated transport device for biotech reagents, comprises:

[0015] S1. Insert the test tubes storing the biological reagents to be transported by refrigeration into the elastic rack, and then push the placement box into the refrigerator to refrigerate the reagents at low temperature;

[0016] S2, using the handle of the refrigerated box to lift it and move it to the transfer destination;

[0017] S3, rotating the threaded rod to control the movable shell to move forward and backward, so that the through slot 1 and the through slot 2 are staggered, separating the inside and outside environments of the placement box, and then pulling the placement box until the insulation board fits the opening of the refrigerator;

[0018] S4, determining whether to remove some or all of the test tubes in the placement box;

[0019] S5. When it is necessary to take out a part of the test tube, the threaded rod is rotated to make the through slot 1 overlap with the through slot 2, and the gear is rotated to control the elastic rack to move upward together with the test tube to protrude out of the placement box, and then the required test tube is taken out and moved to the refrigerator to complete the transportation of the part of the test tube;

[0020] S6. When it is determined that all the test tubes have been taken out, the insulation board is separated from the placement box, and then the placement box is pulled out as a whole and moved to a refrigerator, thereby completing the transportation of all the test tubes.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] The present invention rotates the threaded rod when the placement box needs to be pulled out to take out the test tube or put in a new test tube, and the threaded rod drives the movable shell to move forward and backward until the through slot one and the through slot two are staggered, thereby separating the space inside and outside the placement box, preventing the cold air inside the refrigerator from drifting into the external environment through the through slot one during the process of pulling the placement box out, effectively preventing the loss of cold air and reducing the subsequent refrigeration performance of the refrigerator, and preventing the cold air from blowing to the user to cause frostbite and discomfort, thereby facilitating use by personnel. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative labor. Among them:

[0024] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0025] Figure 2 It is a schematic diagram of the internal structure of the present invention;

[0026] Figure 3 It is a schematic diagram of the placement mechanism structure of the present invention;

[0027] Figure 4 It is a schematic diagram of the internal structure of the placement box of the present invention;

[0028] Figure 5 It is a schematic diagram of the unfolded structure of the placement box of the present invention;

[0029] Figure 6 It is a schematic diagram of the local structure of the elastic frame of the present invention;

[0030] Figure 7 The figure is a flowchart of the method steps of the present invention.

[0031] In the figure: 1. Refrigerator; 2. Placement mechanism; 201. Placement box; 202. Rotating wheel; 203. Handle; 204. Insulation board; 205. Slide bar; 206. Magnetic block; 207. Elastic frame; 208. Bracket; 2081. Bearing; 2082. Fixed block; 2083. Stop block; 2084. Connecting rod; 3. Insulation mechanism; 301. Through slot 1; 302. Through slot 2; 303. Movable shell; 304. Movable block; 305. Threaded rod; 4. Cache mechanism; 401. Movable seat; 402. Slide rail; 403. Gear; 404. Rack; 405. Movable frame. DETAILED DESCRIPTION

[0032] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0033] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0034] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0035] As attached Figure 1 , 2 , 3 and attached Figure 4 As shown:

[0036] Embodiment 1: This embodiment provides a biotechnology reagent refrigeration and transportation device, including a cold storage box 1, a placement mechanism 2 and an insulation mechanism 3; the placement mechanism 2 includes a placement box 201 movably arranged in the cold storage box 1, a plurality of elastic frames 207 are movably arranged in the placement box 201, and a bracket 208 is fixedly installed at the bottom of the elastic frame 207; the insulation mechanism 3 includes a plurality of through grooves 1 301 arranged at the top and bottom of the placement box 201, a movable shell 303 is movably arranged in the placement box 201, a plurality of through grooves 2 302 are arranged at the top and bottom of the movable shell 303, the through grooves 1 301 are adapted to the through grooves 2 302, movable blocks 304 are fixedly installed on both sides of the movable shell 303, a threaded rod 305 is movably arranged on the placement box 201, and the threaded rod 305 is threadedly connected to the movable block 304.

[0037] When in use, the placement box 201 is first pulled out, and then the test tubes storing the biological reagents to be refrigerated and transported are inserted into the elastic rack 207, and then the placement box 201 is pushed back into the refrigerator 1, and the handle of the refrigerator 1 is held and lifted to carry out the refrigeration and transportation of the reagents. The refrigerator 1 adopts the existing refrigerator 1, and its refrigeration principle belongs to the existing technology, so it will not be redundantly described;

[0038] The internal environment of the refrigerator 1 is connected to the internal environment of the placement box 201 through the through slot 1 301, and the cold air enters the placement box 201 through the through slot 1 301. The test tube is located between the upper and lower through slots 1 301 of the placement box 201, and thus directly and completely contacts the cold air, thereby ensuring the refrigeration effect;

[0039] When the placement box 201 needs to be pulled out to take out a test tube or put in a new test tube, the threaded rod 305 is first rotated, and the threaded rod 305 will drive it to move forward and backward through the threaded connection relationship with the movable block 304, and then drive the movable shell 303 to move forward and backward until the through slot 1 301 and the through slot 2 302 are staggered, separating the inner and outer spaces of the placement box 201, so as to prevent the cold air inside the refrigerator 1 from entering the placement box 201 through the through slot 1 301 during the process of pulling out the placement box 201, and then drifting to the external environment through the through slot 1 301 already located outside the refrigerator 1, effectively preventing the loss of cold air from reducing the subsequent refrigeration performance of the refrigerator 1, and preventing the cold air from blowing to the user to cause frostbite and discomfort, so as to facilitate the use of personnel;

[0040] Two threaded rods 305 are provided to avoid accidental touching of a single threaded rod, and both hands can be used to rotate the threaded rod at the same time during use, thereby dispersing resistance and reducing labor intensity.

[0041] As attached Figure 2 and attached Figure 3 As shown:

[0042] Specifically, slide bars 205 are fixedly installed inside the cold storage box 1 on both sides of the placement box 201, and a heat preservation plate 204 is slidably arranged between the slide bars 205 at the other end of the placement box 201.

[0043] Specifically, magnetic blocks 206 are fixedly mounted on the rear end surface of the placement box 201 and the front end surfaces of the insulation plates 204 on both sides of the placement box 201 .

[0044] As can be seen from the above, when the personnel pulls the placement box 201, the placement box 201 will drive the insulation board 204 to move synchronously through the magnetic block 206, and the insulation board 204 will slide on the slide bar 205 to limit the position of the insulation board 204 so that it can only slide horizontally forward and backward. When the placement box 201 is pulled to the end point, that is, all the through grooves 1 301 are exposed outside the cold storage box 1, the insulation board 204 will fit the front end surface of the interior of the cold storage box 1, which has a limiting effect, avoiding the placement box 201 from being completely pulled out, and at the same time blocking and sealing the opening of the cold storage box 1. At this time, the staff member reversely rotates the threaded rod 305 to make the through groove 1 301 overlap with the through groove 2 302 to place and take out the test tube. The internal and external environments of the cold storage box 1 are still isolated, avoiding cold air leakage and improving the insulation effect.

[0045] When there are many test tubes that need to be transported and taken out at the location, the placement box 201 can be directly completely pulled out from the cold storage box 1, and the insulation board 204 will be adsorbed and fixed in the cold storage box 1 through the magnetic suction block 206 located on the front end surface thereof, and the sealing and insulation effect is still maintained. Since the through groove 1 301 and the through groove 2 302 of the placement box 201 are staggered, the internal environment of the placement box 201 is isolated from the external environment, and the cold air remaining inside can still be used for a period of refrigeration. Then, the placement box 201 is moved to the refrigerator at the location, and the test tubes that need to be transported are completely taken out and returned to the cold storage box 1, and the magnetic suction block 206 at the rear end of the placement box 201 is used to connect with the insulation board 204 again to restore the initial state;

[0046] Alternatively, the placement box 201 can be left in the refrigerator, and a new placement box 201 can be connected to the insulation board 204 and pushed into the refrigerator 1. In this state, the staff can put the test tubes into the new placement box 201 in advance, and the assembly and replacement can be completed quickly when the refrigerator 1 arrives, thereby improving the transportation efficiency.

[0047] As attached Figure 4 and attached Figure 5 As shown:

[0048] Embodiment 2: This embodiment is basically the same as the previous embodiment, except that the reagent refrigeration and transportation device also includes a cache mechanism 4, the cache mechanism 4 includes a movable frame 405 movably arranged between the placement box 201 and the elastic frame 207, movable seats 401 are fixedly installed at both ends of the movable frame 405, racks 404 are arranged on both sides of the movable seat 401, and a gear 403 is arranged on the inner front end of the placement box 201, and the gear 403 is meshed with the rack 404.

[0049] Specifically, both ends of the placement box 201 are provided with slide rails 402 , and the slide rails 402 are slidably connected to the movable seat 401 .

[0050] Specifically, the front ends of the gear 403 and the threaded rod 305 penetrate the placement box 201 and are equipped with a rotating wheel 202. The front end of the placement box 201 is fixedly equipped with a handle 203. The gear 403 and the threaded rod 305 can be controlled by rotating the rotating wheel 202, which is convenient for personnel to control and use.

[0051] As attached Figure 6 As shown:

[0052] Specifically, a bearing 2081 is installed between the elastic frame 207 and the movable frame 405 , a fixed block 2082 is fixedly installed on the elastic frame 207 , and a stopper 2083 is fixedly installed on the movable frame 405 on the rotational movement path of the fixed block 2082 .

[0053] Specifically, a connecting rod 2084 is movably installed between the brackets 208 of the plurality of elastic frames 207 .

[0054] As can be seen from the above, when a person needs to place or take out a test tube, the through slot 1 301 and the through slot 2 302 are staggered, and then the gear 403 is rotated. The gear 403 will drive the movable seat 401 to move up and down by meshing with the rack 404. The slide rail 402 will limit the moving direction and moving range of the movable seat 401 to ensure stability. When the movable seat 401 moves, it will drive the elastic frame 207 and the test tube to move upward through the movable frame 405 until the test tube is protruded from the through slot 1 301 into the placement box 201, so that the person can take out the test tube and place a new test tube conveniently.

[0055] Two gears 403 are used to avoid accidental touching of a single gear, and both hands can be used to rotate at the same time during use, thereby dispersing resistance and reducing labor intensity;

[0056] The elastic frame 207 rotates on the movable frame 405 through the bearing 2081. When the elastic frame 207 rotates, it drives the fixed block 2082 to rotate synchronously. The stopper 2083 is located on the rotation path of the fixed block 2082. When the elastic frame 207 swings 45° back and forth, it contacts the stopper 2083 to stop the swinging under the obstruction of the stopper 2083, so as to avoid the situation that the reagent flows to the opening of the test tube due to excessive swinging amplitude.

[0057] The connecting rod 2084 connects all the elastic racks 207 together to make them rotate and swing synchronously, thereby preventing the test tubes from being damaged due to inconsistent swing amplitudes of adjacent elastic racks 207;

[0058] After the personnel completely takes out the placement box 201 from the cold storage box 1, the placement box 201 can be adjusted from the horizontal level to the vertical level. During the process, the test tube will shake due to the change in the center of gravity of the internal reagent until it is rotated 45°, so that the reagent is always located at the bottom of the test tube to ensure stability. The placement box 201 can be formed into a small suitcase-type refrigerated transport device, and the personnel can hold the handle 203 to pick it up and carry it, and the personnel can frequently switch the horizontal and vertical directions of the placement box 201 to make the test tube shake in the device to achieve a shaking effect, thereby avoiding the precipitation of reagents during transportation and affecting subsequent observations, which is convenient for personnel to use.

[0059] As attached Figure 7 As shown:

[0060] Embodiment 3: A method for refrigerating and transporting a biotechnology reagent, using the above-mentioned refrigerated transport device for biotechnology reagents, comprising:

[0061] S1, insert the test tubes storing the biological reagents to be refrigerated and transported into the elastic rack 207, and then push the placement box 201 into the refrigerator 1, and use the refrigerator 1 to refrigerate the reagents at low temperature;

[0062] S2, using the handle of the cold storage box 1 to lift it and move it to the transfer destination;

[0063] S3, rotating the threaded rod 305 to control the movable shell 303 to move forward and backward, so that the through slot 1 301 and the through slot 2 302 are staggered, separating the inside and outside environments of the placement box 201, and then pulling the placement box 201 until the insulation plate 204 fits the opening of the refrigerator 1;

[0064] S4, determining whether to take out some or all of the test tubes in the placement box 201;

[0065] S5. When it is necessary to take out a part of the test tube, the threaded rod 305 is rotated to make the through slot 1 301 overlap with the through slot 2 302, and the gear 403 is rotated to control the elastic frame 207 to move upward together with the test tube to protrude out of the placement box 201, and then the required test tube is taken out and moved to the refrigerator, completing the transportation of the part of the test tube;

[0066] S6. When it is determined that all the test tubes have been taken out, the heat preservation plate 204 is separated from the placement box 201, and then the placement box 201 is pulled out as a whole and moved to the refrigerator, thereby completing the transportation of all the test tubes.

[0067] Importantly, it should be noted that the construction and arrangement of the present application shown in a plurality of different exemplary embodiments are only exemplary. Although only a few embodiments are described in detail in this disclosure, it should be readily understood by those who refer to this disclosure that many modifications are possible (e.g., the size, scale, structure, shape and proportion of various elements, and parameter values ​​(e.g., temperature, pressure, etc.), installation arrangement, use of materials, color, directional changes, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in the application. For example, the element shown as integrally formed can be composed of multiple parts or elements, the position of the element can be inverted or otherwise changed, and the nature or number or position of the discrete element can be changed or changed. Therefore, all such modifications are intended to be included in the scope of the present invention. The order or sequence of any process or method steps can be changed or reordered according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure of performing the function described herein, and is not only structurally equivalent but also equivalent structure. Without departing from the scope of the present invention, other replacements, modifications, changes and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments. Therefore, the invention is not limited to a specific embodiment, but extends to several modifications still falling within the scope of the appended claims.

[0068] Additionally, in order to provide a concise description of exemplary embodiments, all features of an actual embodiment may not be described (ie, those features that are not relevant to the best mode presently contemplated for carrying out the invention or those that are not relevant to implementing the invention).

[0069] It will be appreciated that in the development of any actual implementation, as in any engineering or design project, numerous implementation-specific decisions may be made. Such a development effort may be complex and time-consuming, but will be a routine task of design, fabrication, and production for those of ordinary skill having the benefit of this disclosure without undue experimentation.

[0070] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A biotechnology reagent refrigeration and transportation device, characterized in that: It comprises a cold storage box (1), a placement mechanism (2) and a heat preservation mechanism (3); The placement mechanism (2) comprises a placement box (201) movably arranged in the refrigerator (1), a plurality of elastic frames (207) movably arranged in the placement box (201), and a bracket (208) is fixedly installed at the bottom of the elastic frame (207); The heat preservation mechanism (3) comprises a plurality of through slots (301) arranged at the top and bottom of the placement box (201); a movable shell (303) is movably arranged in the placement box (201); a plurality of through slots (302) are arranged at the top and bottom of the movable shell (303); the through slots (301) are matched with the through slots (302); movable blocks (304) are fixedly installed on both sides of the movable shell (303); a threaded rod (305) is movably arranged on the placement box (201); and the threaded rod (305) is threadedly connected to the movable block (304).

2. A biotechnology reagent refrigeration and transportation device according to claim 1, characterized in that: Sliding rods (205) are fixedly installed inside the cold storage box (1) on both sides of the placement box (201), and a heat preservation plate (204) is slidably arranged between the sliding rods (205) at the other end of the placement box (201).

3. A biotechnology reagent refrigeration and transportation device according to claim 2, characterized in that: Magnetic blocks (206) are fixedly mounted on the rear end surface of the placement box (201) and the front end surfaces of the insulation plates (204) on both sides of the placement box (201).

4. A biotechnology reagent refrigeration and transportation device according to claim 1, characterized in that: The reagent refrigeration and transportation device also includes a quick-access mechanism (4), which includes a movable frame (405) movably arranged between the placement box (201) and the elastic frame (207), and movable seats (401) are fixedly installed at both ends of the movable frame (405), and racks (404) are arranged on both sides of the movable seat (401), and a gear (403) is arranged at the internal front end of the placement box (201), and the gear (403) is meshed with the rack (404).

5. A biotechnology reagent refrigeration and transportation device according to claim 4, characterized in that: Slide rails (402) are provided at both ends of the placement box (201), and the slide rails (402) are slidably connected to the movable seat (401).

6. A biotechnology reagent refrigeration and transportation device according to claim 4, characterized in that: The front ends of the gear (403) and the threaded rod (305) both penetrate the placement box (201) and are equipped with a rotating wheel (202), and the front end of the placement box (201) is fixedly equipped with a handle (203).

7. A biotechnology reagent refrigeration and transportation device according to claim 4, characterized in that: A bearing (2081) is installed between the elastic frame (207) and the movable frame (405), a fixed block (2082) is fixedly installed on the elastic frame (207), and a stopper (2083) is fixedly installed on the movable frame (405) on the rotational movement path of the fixed block (2082).

8. The biotechnology reagent refrigeration and transportation device according to claim 1, characterized in that: A connecting rod (2084) is movably installed between the brackets (208) of the plurality of elastic frames (207).

9. A method for refrigerated transportation of biotechnology reagents, characterized in that: A biotechnology reagent refrigeration and transportation device according to any one of claims 1 to 8, comprising: S1, inserting the test tubes storing the biological reagents to be refrigerated and transported into the elastic rack (207), and then pushing the placement box (201) into the refrigerator (1), and using the refrigerator (1) to refrigerate the reagents at low temperature; S2, using the handle of the cold storage box (1) to lift it and move it to the transfer destination; S3, rotating the threaded rod (305) to control the movable shell (303) to move forward and backward, so that the through slot 1 (301) and the through slot 2 (302) are staggered, separating the inside and outside environments of the placement box (201), and then pulling the placement box (201) until the insulation plate (204) fits the opening of the refrigerator (1); S4, determining whether to take out some or all of the test tubes in the placement box (201); S5. When it is necessary to take out a part of the test tube, the threaded rod (305) is rotated to make the through slot 1 (301) overlap with the through slot 2 (302), and the gear (403) is rotated to control the elastic frame (207) to move upward together with the test tube to protrude out of the placement box (201), and then the required test tube is taken out and moved to the refrigerator, thereby completing the transportation of the part of the test tube; S6. When it is determined that all the test tubes have been taken out, the heat preservation plate (204) is separated from the placement box (201), and then the placement box (201) is pulled out as a whole and moved to a cold storage cabinet, thereby completing the transportation of all the test tubes.

Images