Hemoperfusion device supporting device and dialysis machine with combination of hemoperfusion and hemodialysis thereof

Abstract

The invention discloses a hemoperfusion device supporting device and a dialysis machine with combination of hemoperfusion and hemodialysis. The hemoperfusion device supporting device comprises a mounting base, a right telescopic air cylinder I, an L-shaped support, a hemoperfusion device support rotating motor, a dialyzer support rotating motor, a hemoperfusion device support and a dialyzer support. The L-shaped support is fixedly connected to the right telescopic air cylinder I. The dialyzer support rotating motor is fixedly installed on the top of the L-shaped support, the dialyzer support is installed on a power output shaft of the dialyzer support rotating motor, and the perfusion device support rotating motor is fixedly installed at the right end of the bottom of the L-shaped support. According to the hemoperfusion device supporting device and the dialysis machine, automatic overturning, inclination and vibration are achieved, then automatic air exhausting and impurity discharging in a hemoperfusion device and a dialyzer are achieved, manual operation is not needed, the hemoperfusion device and the dialyzer can synchronously conduct pre-flushing air exhausting and impurity discharging, time is saved, dependence on medical staff is reduced, and the working efficiency is improved. And the infection risk caused by subsequent connection of a human arteriovenous puncture needle connector through manual operation is also reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of hemodialysis, and in particular to a hemoperfusion device supporting device and a hemoperfusion combined hemodialysis dialysis machine thereof. Background Art

[0002] Hemoperfusion devices are mainly used for the adsorption of medium-molecular toxins in acute and chronic drug poisoning and uremia, and the adsorption of pathogenic factors in the fields of liver disease and immunity. The main application modes include single hemoperfusion mode, hemodialysis combined with hemoperfusion mode, and plasma separation and adsorption mode. Hemodialysis combined with hemoperfusion mode makes up for the deficiency of simple hemodialysis that cannot effectively remove medium- and large-molecular toxins, protein-bound toxins, and various inflammatory mediators. However, the overall structure, connection method, and pre-flushing method of the combined artificial kidney extracorporeal circulation are more complicated than those of simple dialysis, resulting in an increased risk of infection and coagulation in patients.

[0003] When performing hemoperfusion combined with hemodialysis, install the dialyzer on the bracket tube clamp, and then install the perfusion device on another bracket tube clamp, with the venous end of the perfusion device facing upwards, connect the arteriovenous line of the perfusion device, and the venous end of the dialyzer facing upwards, connect the dialysis venous line to the venous end of the dialyzer, manually rotate the bracket, and then connect the dialysis arterial line to the arterial end of the dialyzer, and then manually reverse the bracket to return the venous end of the dialyzer to the top again. Pre-flush the perfusion device, and follow the quick exhaust guide to fully exhaust the air and particles in the perfusion device. Step 1: Manually remove the perfusion device, open the pre-flush liquid, exhaust the air and particles from the arterial end and the column, manually tilt the perfusion device, and the horizontal angle is about 30 to 60 degrees. The other hand holds the exhaust hammer and continuously hits the bottom of the perfusion device; Step 2: Exhaust the venous end, hold it vertically, and exhaust the bubbles. After the perfusion device is vented and particles are removed, the dialyzer is pre-flushed. When the dialyzer is pre-flushed and vented, the pre-flushing liquid enters the dialyzer from the arterial end at the bottom of the dialyzer and is discharged from the venous end at the top, thereby expelling the gas and impurities in the dialyzer membrane. In order to better discharge the gas and impurities in the dialyzer membrane, the operator needs to pat the dialyzer or remove the dialyzer for rubbing. After the gas in the dialyzer membrane is discharged, the bypass interface on the side wall of the dialyzer is connected to the bypass line, and the bracket is manually rotated again to make the arterial end of the dialyzer higher than the venous end. The dialyzer enters the dialyzer from the bypass line at the bottom and is discharged from the bypass line at the top, thereby flushing the outside of the dialyzer membrane. After the pre-washing is completed, the other ends of the dialysis arterial line and the dialysis venous line are connected to the patient's arteriovenous puncture needle, and hemoperfusion dialysis can begin.

[0004] It can be seen from the existing pre-flushing of the perfusion device and dialyzer that the flipping, tilting and patting of the perfusion device and dialyzer are all manual operations. The entire operation needs to be done manually to exhaust the gas and particles in the perfusion device, the impurities in the dialyzer, and the gas inside and outside the dialyzer membrane. This depends entirely on whether the medical staff's operation is standardized and serious. If the operation is sloppy or interrupted in the middle, the gas and particles in the perfusion device, the impurities in the dialyzer, and the gas inside and outside the dialyzer membrane cannot be completely exhausted, and there is a risk of embolism. At the same time, manual flipping, tilting and patting require the hands to contact different parts of the perfusion device, dialyzer and bracket and different time periods, which brings infection risks to the subsequent connection of the human arterial and venous puncture needle connector. When operating, medical staff must first pre-flushed and exhaust the perfusion device, and then pre-flushed and exhaust the dialyzer, which cannot be done synchronously, so the operation time is increased. Summary of the invention

[0005] In view of the deficiencies in the above-mentioned prior art, the present invention provides a blood perfusion device support device and a hemoperfusion combined with hemodialysis dialysis machine which can reduce manual operations and automatically realize flipping, tilting and vibration of the perfusion device and dialyzer.

[0006] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0007] The blood perfusion device support device comprises a mounting base, a right telescopic cylinder I, an L-shaped bracket, a perfusion device bracket rotating motor, a dialyzer bracket rotating motor, a perfusion device bracket and a dialyzer bracket; the right telescopic cylinder I is fixedly connected to the mounting base, the piston rod of the right telescopic cylinder I extends horizontally to the right, the L-shaped bracket is fixedly connected to the piston rod of the right telescopic cylinder I, the dialyzer bracket rotating motor is fixedly installed on the top of the L-shaped bracket, the power output shaft of the dialyzer bracket rotating motor extends to the right, and the dialyzer bracket is installed on the dialyzer bracket rotating motor. The bottom of the L-shaped bracket extends to the right from the bottom of the dialyzer bracket, the perfusion bracket rotating motor is fixedly installed on the bottom right end of the L-shaped bracket, the power output shaft of the perfusion bracket rotating motor extends to the right, and the perfusion bracket is installed on the power output shaft of the perfusion bracket rotating motor; the perfusion bracket includes a U-shaped frame, a perfusion left support frame and a perfusion right support frame; the left middle part of the U-shaped frame is fixedly connected to the power output shaft of the perfusion bracket rotating motor, and the perfusion left support frame is installed on the U-shaped frame The left top end of the U-shaped frame, the right support frame of the irrigator is installed on the right top end of the U-shaped frame, and the left support frame of the irrigator and the right support frame of the irrigator are symmetrically arranged on the left and right sides of the U-shaped frame; the left support frame of the irrigator includes a left guide sleeve, a left cylinder II, a left guide plate, a left sliding sleeve, a left spring, a left clamp, a left pull rope and a left vibration motor of the irrigator; the left guide sleeve is fixed on the left top end of the U-shaped frame, the open end of the left guide sleeve faces right, the left cylinder II is installed on the left side of the left guide sleeve, the left guide plate is fixedly arranged on the cross section of the left guide sleeve, and the left sliding sleeve passes through The left end of the left sliding sleeve is fixedly connected to the piston rod of the left cylinder II through a through hole set in the middle part of the left guide plate and slidingly cooperates with the left guide plate. The left spring is sleeved on the left sliding sleeve, and the left end of the left spring is fixed on the left guide plate. The right end of the left spring extends out of the right end of the left guide sleeve and is fixedly connected to the left clamping plate. The left pull rope passes through the left sliding sleeve, and the left end of the left pull rope is fixedly connected to the piston rod of the left cylinder II. The right end of the left pull rope is fixedly connected to the left side of the left clamping plate. The left vibration motor of the irrigation device is fixedly installed on the left side of the left clamping plate near the bottom or near the top.

[0008] As a preferred embodiment of the present invention, the right support frame of the irrigator includes a right guide sleeve, a right cylinder III, a right guide plate, a right sliding sleeve, a right spring, a right clamp, a right pull rope and a right vibration motor of the irrigator; the right guide sleeve is fixed on the top right side of the U-shaped frame, the open end of the right guide sleeve faces left, the right cylinder III is installed on the right side of the right guide sleeve, the right guide plate is fixedly arranged on the cross section of the right guide sleeve, the right sliding sleeve passes through the through hole arranged in the middle of the right guide plate and slides with the right guide plate, and the right end of the right sliding sleeve is in contact with the piston of the right cylinder III The rod is fixedly connected, the right spring is sleeved on the right sliding sleeve, the right end of the right spring is fixed on the right guide plate, the left end of the right spring extends out of the left end of the right guide sleeve and is fixedly connected to the right clamping plate, the right pull rope passes through the right sliding sleeve, the right end of the right pull rope is fixedly connected to the piston rod of the right cylinder III, the left end of the right pull rope is fixedly connected to the right side of the right clamping plate, and the right vibration motor of the irrigation device is fixedly installed on the right side of the right clamping plate near the bottom or near the top; the left clamping plate and the right clamping plate are both arc-shaped plates, and the concave arc-shaped surfaces of the left clamping plate and the right clamping plate correspond to each other.

[0009] As a preferred solution of the present invention, the right end of the left sliding sleeve is provided with an inwardly concave arc end which can be fitted with the left outer wall of the left splint, and the left end of the right sliding sleeve is provided with an inwardly concave arc end which can be fitted with the right outer wall of the right splint; a semicircular frame bent backwards is provided near the middle of the bottom of the U-shaped frame.

[0010] As a preferred embodiment of the present invention, the dialyzer support includes a left support plate and a right support plate; the left support plate and the right support plate are both arc-shaped plates, the concave arc-shaped surfaces of the left support plate and the right support plate correspond to each other, the rear ends of the left support plate and the right support plate are hinged to each other, and the clamping end of the dialyzer is formed between the front ends of the left support plate and the right support plate, and the power output shaft of the dialyzer support rotating motor is fixedly connected to the left side surface of the left support plate; the left support plate and the right support plate are provided with a clamping mechanism for clamping the dialyzer and a vibration mechanism for vibrating the dialyzer.

[0011] As a preferred embodiment of the present invention, the vibration mechanism includes a left vibration mechanism installed in the middle of the inner side of the left support plate and a right vibration mechanism installed in the middle of the inner side of the right support plate. The left vibration mechanism and the right vibration mechanism both include a cylinder IV, a guide cylinder with an open end, a vibration spring, a vibration clamp and a dialyzer vibration motor. The middle of the left support plate and the right support plate are both provided with a cylinder IV mounting hole. The left cylinder IV is fixedly installed in the cylinder IV mounting hole of the left support plate, and the right cylinder IV is fixedly installed in the cylinder IV mounting hole of the right support plate. The piston rod of the cylinder IV faces inward, and the guide cylinder is fixedly connected On the piston rod of cylinder IV, one end of the vibration spring is fixedly connected to the inner end wall of the guide cylinder, and the other end of the vibration spring extends out of the open end of the guide cylinder and is fixedly connected to the vibration clamping plate. The outer diameter of the guide cylinder is smaller than the inner diameter of the mounting hole of cylinder IV. The vibration clamping plate is an arc-shaped plate. The concave arc-shaped surfaces of the left vibration clamping plate and the right vibration clamping plate correspond to each other, and the left vibration clamping plate and the right vibration clamping plate are used to clamp the dialyzer during vibration. The dialyzer vibration motor on the left is installed at the left bottom of the left vibration clamping plate, and the dialyzer vibration motor on the right is installed at the right top of the right vibration clamping plate.

[0012] As a preferred embodiment of the present invention, a clamping mechanism is installed on the inner side of the left support plate near the upper and lower sides and the inner side of the right support plate near the upper and lower sides, the clamping mechanism includes a clamping cylinder V and a clamping plate, the inner side of the left support plate near the upper and lower sides and the inner side of the right support plate near the upper and lower sides are provided with cylinder V mounting holes, a clamping cylinder V is installed in each cylinder V mounting hole, the piston rod of the clamping cylinder V faces inward, and the piston rod of the clamping cylinder V is fixedly connected with a clamping plate, the clamping plate is an arc-shaped plate, the clamping plate on the inner side of the left support plate near the upper side and the clamping plate on the inner side of the right support plate near the upper side form a group of dialyzer clamping plates, and the clamping plate on the inner side of the left support plate near the lower side and the clamping plate on the inner side of the right support plate near the lower side form another group of dialyzer clamping plates.

[0013] As a preferred solution of the present invention, the rear ends of the left support plate and the right support plate are hinged to each other through a positioning and rotating mechanism, the positioning and rotating mechanism includes a positioning shaft and a torque spring, the rear end of the left support plate is provided with at least two inner grooves near the inner side, the rear end of the right support plate is provided with an outer convex rotating arm whose number is equal to the inner grooves and cooperates with each other, the rear end of the left support plate and the outer convex rotating arm are both provided with a through hole I, the outer convex rotating arm on the rear end of the right support plate is located in the inner groove on the corresponding rear end of the left support plate, the positioning shaft passes through the through hole I on the rear end of the left support plate and the through hole I on the outer convex rotating arm, and a torque spring is sleeved on the positioning shaft in each inner groove and at both ends of the corresponding outer convex rotating arm, one end of the torque spring is fixedly connected to the corresponding inner groove side wall, and the other end of the torque spring is fixedly connected to the corresponding outer convex rotating arm. When the torque spring is in a natural state, the snap-in ends of the front ends of the left support plate and the right support plate are close to each other.

[0014] As a preferred solution of the present invention, rubber pads are arranged on the inner sides of the left clamping plate, the right clamping plate, the vibration clamping plate and the clamping plate, and a pressure sensor and an inclination sensor are installed on the inner side of each rubber pad.

[0015] A dialysis machine for hemoperfusion combined with hemodialysis comprises a dialysis machine body and the above-mentioned hemoperfusion device support device; the mounting base comprises a snap-in section and an external connection section, the cross section of the snap-in section is a rectangular structure, and the four faces of the snap-in section are provided with snap-in slots; a snap-in hole with a rectangular cross section is provided on the front side of the dialysis machine body and close to the right side, and a mounting hole corresponding to the snap-in slot is provided on each face of the inner wall of the snap-in hole, the mounting hole is composed of a circular hole section I with a small diameter close to the inner side and a circular hole section II with a large diameter close to the outer side, and a locking mechanism is installed in each mounting hole; the locking mechanism comprises a cylinder VI, a fixing plate, a guide locking sleeve, a locking pin, a locking spring and a locking rope; the cylinder VI is installed in the circular hole section I, the fixing plate is clamped in the circular hole section II and is close to the step formed between the circular hole section I and the circular hole section II, and the fixing plate is fixed to the circular hole section II and is fixed to the step formed between the circular hole section I and the circular hole section II. A guide hole is set in the middle of the fixed plate, the guide locking sleeve passes through the guide hole and slides with the guide hole, the locking pin is set in the circular hole section II and slides with the inner wall of the circular hole section II, the inner end of the locking pin is fixedly connected to the outer end of the guide locking sleeve, the piston rod of the cylinder VI extends to the inner end of the guide locking sleeve, the locking spring is sleeved outside the guide locking sleeve and is located between the locking pin and the fixed plate, one end of the locking spring is fixed to the inner end of the locking pin, and the other end of the locking spring is fixed to the fixed plate, the locking rope passes through the guide locking sleeve, one end of the locking rope is fixedly connected to the inner end of the locking pin, and the other end of the locking rope is fixedly connected to the piston rod of the cylinder VI; the snap-in section is inserted into the snap-in hole, and the outer end of the locking pin is inserted into the corresponding slot; the right telescopic cylinder I is fixedly connected to the front end of the external section.

[0016] Furthermore, the pressure sensor and the tilt sensor are both electrically connected to the controller in the dialyzer body, and the right telescopic cylinder I, the perfusion device support rotating motor, the dialyzer bracket rotating motor, the left cylinder II, the right cylinder III, the perfusion device left vibration motor, the perfusion device right vibration motor, the cylinder IV, the dialyzer vibration motor, the clamping cylinder V and the cylinder VI are all controlled by the controller in the dialyzer body.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] 1. The hemoperfusion device support device and its hemoperfusion combined with hemodialysis dialysis machine realize automatic flipping of the perfusion device and dialyzer, automatic tilting of the perfusion device and dialyzer, and automatic vibration of the perfusion device and dialyzer, thereby realizing automatic exhaust and impurity removal in the perfusion device and dialyzer, without manual operation. Medical personnel only need to connect the venous end, arterial end and bypass interface, which greatly reduces manual operation, thereby reducing the chance of contact with the instrument and reducing the risk of infection caused by manual operation and subsequent connection of the human arterial and venous puncture needle connector. At the same time, through automatic control, the perfusion device and dialyzer can be pre-flushed to exhaust and remove impurities simultaneously, which not only saves time, but also avoids the risk of embolism caused by the improper operation of medical personnel affecting the impurities in the perfusion device and the dialyzer and the gas inside and outside the dialyzer membrane cannot be completely discharged, greatly reducing the dependence on medical personnel, so that the pre-flushing of the perfusion device and the exhaust of gas and impurities inside and outside the dialyzer membrane are better guaranteed.

[0019] 2. When the blood perfusion combined with hemodialysis is used to pre-flushing exhaust and remove particles from the perfusion device, the piston rods of the left cylinder II and the right cylinder III are retracted a short distance, so that the left sliding sleeve leaves the left clamping plate, the right sliding sleeve leaves the right clamping plate, and the left and right pull ropes are in a relaxed state, so that the perfusion device is suspended on the U-shaped frame by the left spring and the right spring. The left vibration motor and the right vibration motor of the perfusion device are turned on, and the pre-flushing liquid is injected, and the motor on the perfusion device bracket is rotated to drive the perfusion device bracket to tilt forward or backward, so that the perfusion device is in multi-dimensional vibration, so that the gas in the perfusion device, including the gas and particles between the solid adsorbents in the perfusion device, on the solid adsorbents and on the inner wall of the perfusion device, moves upward in multiple dimensions and is discharged from the top of the perfusion device, so that the gas and particles in the perfusion device can be discharged efficiently and completely in a short time.

[0020] 3. When the hemoperfusion combined with hemodialysis is used to pre-flushed the dialyzer for exhaust and impurities, the dialyzer is clamped between the left support plate and the right support plate, and the controller controls the piston rod of cylinder IV to extend, and the piston rod drives the guide cylinder to move toward the middle, thereby driving the vibration spring and the vibration clamp plate to approach the dialyzer together, and the elastic pads on the inner side of the left and right vibration clamp plates are pressed on the left and right sides of the dialyzer and clamp the dialyzer, and the dialyzer vibration motors on the left and right sides are turned on. At the same time, the dialyzer bracket rotates the motor to drive the dialyzer to tilt, and the inclination angle sensor on the inner elastic pad of the vibration clamp plate is used to transmit the dialyzer to the dialyzer. The sensor detects the tilt angle of the dialyzer, which is convenient for accurately controlling the tilt angle of the dialyzer; when the priming liquid passes through the dialyzer, the dialyzer vibration motors on the left support plate and the right support plate are at one high and one low, and under the synergistic effect of the dialyzer support rotating motor driving the dialyzer to tilt, the dialyzer moves in multiple dimensions. Driven by the priming liquid, the air and impurities attached to the inner wall of the dialyzer and the fiber membrane in the dialyzer can be separated and discharged as soon as possible, and after the dialyzer is tilted, it is also beneficial for the gas and impurities attached to the top of the dialyzer to be discharged through the venous end or the bypass pipeline. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 is a schematic diagram of the main structure of the hemoperfusion device support device;

[0022] Figure 2 is a schematic diagram of the top view of the structure of the hemoperfusion device support device;

[0023] Figure 3 It is a schematic diagram of the structure in which the hemoperfusion device and the dialyzer are installed on the hemoperfusion device support device;

[0024] Figure 4 It is a schematic diagram of the structure of the installation base;

[0025] Figure 5 is a schematic diagram of the structure of the perfusion device support;

[0026] Figure 6 It is a structural diagram of the U-shaped frame;

[0027] Figure 7 It is a structural schematic diagram of a left sliding sleeve or a right sliding sleeve;

[0028] Figure 8 It is a structural schematic diagram of a clamping mechanism and a vibrating mechanism arranged in the left support plate and the right support plate;

[0029] Fig. 9 is a structural schematic diagram of the left support plate;

[0030] Fig.10 is a structural schematic diagram of the right support plate;

[0031] Fig.11It is a structural schematic diagram of the cooperation between the positioning rotation mechanism and the right support plate;

[0032] Fig.12 It is a schematic diagram of the structure in which a pressure sensor and an inclination sensor are arranged on the rubber pad;

[0033] Fig.13 It is a structural schematic diagram of a blood perfusion device support device installed on a dialysis machine body;

[0034] Fig.14 It is a structural schematic diagram of the card connection holes and the mounting holes provided on the dialysis machine body;

[0035] Fig.15 It is a schematic cross-sectional structure diagram of the insertion section of the mounting base being inserted into the clamping hole on the dialysis machine body;

[0036] Fig.16 yes Fig.15 The enlarged structural diagram at A in the middle;

[0037] Fig.17 It is a schematic diagram of the structure of the perfusion device and dialyzer installed on the dialysis machine.

[0038] In the figure: 1—mounting base; 101—snapping section; 102—external section; 103—slot; 2—right telescopic cylinder I; 3—L-shaped bracket; 4—rotating motor of perfusion device bracket; 5—rotating motor of dialyzer bracket; 6—perfusion device bracket; 61—U-shaped bracket; 611—semicircular bracket; 62—left guide sleeve; 63—left cylinder II; 64—left guide plate; 65—left sliding sleeve; 66—left spring; 67—left clamping plate; 68—left pull rope; 69—left vibration motor of perfusion device; 70—right guide sleeve; 71—right cylinder III; 72—right guide plate; 73—right sliding sleeve; 74—right spring; 75—right clamping plate; 76—right pull rope; 77—right vibration motor of perfusion device; 78—arc end; 8—dialyzer bracket; 81—left support plate; 82—right support plate; 83—clamping mechanism; 831— Clamping cylinder V; 832—clamping plate; 833—mounting hole of cylinder V; 84—vibration mechanism; 841—cylinder IV; 842—guide cylinder; 843—vibration spring; 844—vibration clamping plate; 845—dialyzer vibration motor; 846—mounting hole of cylinder IV; 85—positioning shaft; 86—torque spring; 87—inner groove; 88—outer convex rotating arm; 89—through hole I; 90—rubber pad; 91—pressure sensor; 92—tilt sensor; 10—perfusion device; 11—dialyzer; 12—dialysis machine body; 13—clamping hole; 14—mounting hole; 15—locking mechanism; 151—cylinder IV; 152—fixing plate; 153—guide locking sleeve; 154—locking pin; 155—locking spring; 156—locking rope; 16—base; 17—support arm; 18—support rod. DETAILED DESCRIPTION

[0039] The present invention is described in detail below in conjunction with embodiments and drawings.

[0040] like Figure 1-Figure 3 As shown, the blood perfusion device support device includes a mounting base 1, a right telescopic cylinder I2, an L-shaped bracket 3, a perfusion device bracket rotating motor 4, a dialyzer bracket rotating motor 5, a perfusion device bracket 6 and a dialyzer bracket 8. The right telescopic cylinder I2 is fixedly connected to the mounting base 1. In this embodiment, the mounting base 1 includes a snap-in section 101 and an external section 102. The cross section of the snap-in section 101 is a rectangular structure. The four surfaces of the snap-in section 101 are provided with snap-in grooves 103, as shown in FIG. Figure 4 As shown, the right telescopic cylinder Ⅰ2 is fixedly connected to the front end of the external section 102. The piston rod of the right telescopic cylinder Ⅰ2 extends horizontally to the right, and the left side of the L-shaped bracket 3 is fixedly connected to the piston rod of the right telescopic cylinder Ⅰ2. The dialyzer support rotating motor 5 is fixedly installed on the top of the L-shaped bracket 3, the power output shaft of the dialyzer support rotating motor 5 extends to the right, and the dialyzer support 8 is installed on the power output shaft of the dialyzer support rotating motor 5. The bottom of the L-shaped bracket 3 extends to the right from the bottom of the dialyzer support 8, the irrigator support rotating motor 4 is fixedly installed on the bottom right end of the L-shaped bracket 3, the power output shaft of the irrigator support rotating motor 4 extends to the right, and the irrigator support 6 is installed on the power output shaft of the irrigator support rotating motor 4. The irrigator support 6 is located at the right side of the dialyzer support 8.

[0041] The perfusion device support 6 includes a U-shaped frame 61, a left perfusion device support frame and a right perfusion device support frame. Figure 5 A semicircular frame 611 is disposed near the middle of the bottom of the U-shaped frame 61, and is bent backwards. Figure 6 As shown, the design of the semicircular frame 611 plays a guiding role in the insertion of the cartridge 10 between the left and right cartridge support frames. The cartridge 10 can be placed between the left and right cartridge support frames when the bottom of the cartridge 10 faces the semicircular frame 611, while also avoiding blocking the cartridge 10 from being inserted and hindering the vibration and exhaust of the cartridge 10. The left middle part of the U-shaped frame 61 is fixedly connected to the power output shaft of the cartridge support rotating motor 4, the cartridge left support frame is mounted on the left top end of the U-shaped frame 61, and the cartridge right support frame is mounted on the right top end of the U-shaped frame 61, and the cartridge left support frame and the cartridge right support frame are symmetrically arranged on the U-shaped frame 61.

[0042] The left support frame of the irrigator includes a left guide sleeve 62, a left cylinder II 63, a left guide plate 64, a left sliding sleeve 65, a left spring 66, a left clamping plate 67, a left pull rope 68 and a left vibration motor 69 of the irrigator. Figure 5The left guide sleeve 62 is fixed on the top left side of the U-shaped frame 61, the open end of the left guide sleeve 62 faces right, the left cylinder II 63 is installed on the left side of the left guide sleeve 62, the piston rod of the left cylinder II 63 faces right, the left guide plate 64 is fixedly arranged on the cross section of the left guide sleeve 62, the left sliding sleeve 65 passes through the through hole arranged in the middle of the left guide plate 64 and slides with the left guide plate 64, the left end of the left sliding sleeve 65 is fixedly connected with the piston rod of the left cylinder II 63, the left spring 66 is sleeved outside the left sliding sleeve 65, and the left end of the left spring 66 is fixedly connected with the piston rod of the left cylinder II 63. The left end of the left spring 66 is fixed on the left guide plate 64, the right end of the left spring 66 extends out of the right end of the left guide sleeve 62 and is fixedly connected to the left clamping plate 67, the left pull rope 68 passes through the left sliding sleeve 65, the left end of the left pull rope 68 is fixedly connected to the piston rod of the left cylinder II 63, the right end of the left pull rope 68 is fixedly connected to the left side of the left clamping plate 67, and the left vibration motor 69 of the irrigator is fixedly installed on the left side of the left clamping plate 67 near the bottom or near the top. In this embodiment, the left vibration motor 69 of the irrigator is fixedly installed on the left side of the left clamping plate 67 near the bottom. The right support frame of the irrigator includes a right guide sleeve 70, a right cylinder III 71, a right guide plate 72, a right sliding sleeve 73, a right spring 74, a right clamping plate 75, a right pull rope 76 and a right vibration motor 77 of the irrigator, as shown in FIG. Figure 5 As shown; the right guide sleeve 70 is fixed on the top right side of the U-shaped frame 61, the open end of the right guide sleeve 70 faces left, the left guide sleeve 62 and the right guide sleeve 70 are on the same horizontal axis, the right cylinder III 71 is installed on the right side of the right guide sleeve 70, the piston rod of the right cylinder III 71 faces left, the right guide plate 72 is fixedly arranged on the cross section of the right guide sleeve 70, the right sliding sleeve 73 passes through the through hole set in the middle of the right guide plate 72 and slides with the right guide plate 72, the right end of the right sliding sleeve 73 is fixedly connected to the piston rod of the right cylinder III 71, and the right spring 74 is sleeved on the right sliding sleeve 7 3, the right end of the right spring 74 is fixed on the right guide plate 72, the left end of the right spring 74 extends out of the left end of the right guide sleeve 70 and is fixedly connected to the right clamping plate 75, the right pull rope 76 passes through the right sliding sleeve 73, the right end of the right pull rope 76 is fixedly connected to the piston rod of the right cylinder III 71, the left end of the right pull rope 76 is fixedly connected to the right side of the right clamping plate 75, and the right vibration motor 77 of the irrigation device is fixedly installed on the right side of the right clamping plate 75 near the bottom or near the top; the left clamping plate 67 and the right clamping plate 75 are both arc-shaped plates, and the concave arc surfaces of the left clamping plate 67 and the right clamping plate 75 correspond to each other. The right end of the left sliding sleeve 65 is provided with a concave arc end 78 that can fit with the left outer wall of the left clamping plate 67, and the left end of the right sliding sleeve 73 is provided with a concave arc end 78 that can fit with the right outer wall of the right clamping plate 75, as shown in FIG. Figure 7 As shown, the piston rod of the left cylinder II 63 extends to drive the left sliding sleeve 65 to approach the left outer wall of the left clamping plate 67 and fit it. At the same time, the piston rod of the right cylinder III 71 extends to drive the right sliding sleeve 73 to approach the right outer wall of the right clamping plate 75 and fit it. The arc-shaped end 78 can better fit with the left outer wall of the left clamping plate 67 and the right outer wall of the right clamping plate 75, so that the perfusion device 10 can be better clamped and the clamping is more stable.

[0043] When the irrigation device support 6 is used, the piston rod of the left cylinder II 63 retracts to drive the left sliding sleeve 65 to move to the left, and the left clamping plate 67 is driven to move to the left together through the left pull rope 68, and the left spring 66 is compressed. At the same time, the piston rod of the right cylinder III 71 retracts to drive the right sliding sleeve 73 to move to the right, and the right clamping plate 75 is driven to move to the right together through the right pull rope 76, and the right spring 74 is compressed, and the left clamping plate 67 and the right clamping plate 75 move away from each other. At this time, the irrigation device 10 is placed between the left clamping plate 67 and the right clamping plate 75, and the piston rods of the left cylinder II 63 and the right cylinder III 71 extend. The piston rod of the left cylinder II 63 extends to drive the left sliding sleeve 65 to squeeze the left clamping plate 67, so that the left clamping plate 67 is pressed more firmly on the left side of the irrigation device 10, and the piston rod of the right cylinder III 71 extends to drive the right sliding sleeve 73 to squeeze the right clamping plate 75, so that the right clamping plate 75 is pressed more firmly on the right side of the irrigation device 10. Figure 3 When the cartridge 10 needs to be pre-charged and exhausted, the piston rods of the left cylinder II 63 and the right cylinder III 71 are retracted a short distance, so that the left sliding sleeve 65 leaves the left clamping plate 67, the right sliding sleeve 73 leaves the right clamping plate 75, and the left pull rope 68 and the right pull rope 76 are in a relaxed state, the left clamping plate 67 presses the left side of the cartridge 10 by the driving force of the left spring 66, and the right clamping plate 75 presses the right side of the cartridge 10 by the driving force of the right spring 74. The cartridge 10 is suspended on the U-shaped frame 61 by means of the left spring 66 and the right spring 74. The left vibration motor 69 and the right vibration motor 77 of the cartridge are turned on. Under the injection of the priming liquid, the motor 5 on the cartridge support drives the cartridge support 6 to tilt forward or backward, so that the cartridge 10 is in multi-dimensional vibration, so that the gas in the cartridge 10, including the gas between the solid adsorbents in the cartridge 10, on the solid adsorbents and on the inner wall of the cartridge 10, moves upward in multiple dimensions and is discharged from the top of the cartridge 10, so that the gas in the cartridge 10 can be discharged efficiently and completely in a short time. After the gas and impurities in the cartridge 10 are discharged, the cartridge support rotating motor 5 rotates to drive the cartridge support 6 to be in a vertical state, that is, the cartridge 10 is in a vertical state, and the piston rods of the left cylinder II 63 and the right cylinder III 71 extend. The piston rod of the left cylinder II 63 extends to drive the left sliding sleeve 65 to press against the left outer wall of the left clamping plate 67, and the piston rod of the right cylinder III 71 extends to drive the right sliding sleeve 73 to press against the right outer wall of the right clamping plate 75. At this time, the cartridge 10 further relies on the clamping force of the left sliding sleeve 65 pushed by the left cylinder II 63 and the right sliding sleeve 73 pushed by the right cylinder III 71, so that the cartridge 10 can be more stably clamped between the left clamping plate 67 and the right clamping plate 75 during the hemodialysis process.

[0044] The dialyzer support 8 includes a left support plate 81 and a right support plate 82. Figure 1-Figure 3As shown, the left support plate 81 and the right support plate 82 are both arc plates, and the concave arc surfaces of the left support plate 81 and the right support plate 82 correspond, and the left support plate 81 and the right support plate 82 form an outer support ring. The rear ends of the left support plate 81 and the right support plate 82 are hinged to each other, and the card-in end of the dialyzer 11 is formed between the front ends of the left support plate 81 and the right support plate 82, and the card-in end is an eight-character structure opened to both sides of the front, which is conducive to the dialyzer 11 being carded between the left support plate 81 and the right support plate 82, and the power output shaft of the dialyzer support rotating motor 5 is fixedly connected to the left side of the left support plate 81. A clamping mechanism 83 that can clamp the dialyzer 11 and a vibrating mechanism 84 that can vibrate the dialyzer 11 are provided in the left support plate 81 and the right support plate 82. When the dialyzer 11 is inserted into the outer support ring formed by the left support plate 81 and the right support plate 82 through the insertion end, the clamping mechanism 83 in the left support plate 81 and the right support plate 82 can clamp the dialyzer 11. Figure 3 As shown, at this time, the dialyzer support rotating motor 5 rotates, which can drive the left support plate 81 and the right support plate 82 and the clamping mechanism 83, the vibration mechanism 84 and the dialyzer 11 therein to flip and tilt. When flipping, the venous end of the dialyzer 11 can be flipped to the bottom, and the arterial end of the dialyzer 11 can be flipped to the top, which is convenient for arteriovenous catheter connection. When the vibration mechanism 84 clamps the dialyzer 11, the vibration mechanism 84 is turned on, and under the synergistic effect of the dialyzer support rotating motor 5 driving the dialyzer 11 to tilt, the air and impurities in the dialyzer 11 can be completely and effectively exhausted.

[0045] The vibration mechanism 84 includes a left vibration mechanism installed at the middle of the inner side of the left support plate 81 and a right vibration mechanism installed at the middle of the inner side of the right support plate 82. Figure 8 As shown, the left vibration mechanism and the right vibration mechanism each include a cylinder IV 841, a guide cylinder 842 with one end open, a vibration spring 843, a vibration clamping plate 844 and a dialyzer vibration motor 845. The middle of the left support plate 81 and the right support plate 82 are both provided with a cylinder IV mounting hole 846, as shown in FIG. Fig. 9 and Fig.10As shown, the left cylinder IV 841 is fixedly mounted in the cylinder IV mounting hole 846 of the left support plate 81, and the right cylinder IV 841 is fixedly mounted in the cylinder IV mounting hole 846 of the right support plate 82, and the piston rod of cylinder IV 841 faces inward (i.e., the piston rod of cylinder IV 841 faces toward the middle between the left support plate 81 and the right support plate 82). The guide cylinder 842 is fixedly connected to the piston rod of the cylinder IV 841, one end of the vibration spring 843 is fixedly connected to the inner end wall of the guide cylinder 842, the other end of the vibration spring 843 extends out of the open end of the guide cylinder 842 and is fixedly connected to the vibration clamping plate 844, the outer diameter of the guide cylinder 842 is smaller than the inner diameter of the mounting hole 846 of the cylinder IV, the vibration clamping plate 844 is an arc plate, the concave arc surfaces of the left vibration clamping plate 844 and the right vibration clamping plate 844 correspond to each other, and the left vibration clamping plate 844 and the right vibration clamping plate 844 are used to clamp the dialyzer 11 during vibration, the left dialyzer vibration motor 845 is installed at the left bottom of the left vibration clamping plate 844, and the right dialyzer vibration motor 845 is installed at the right top of the right vibration clamping plate 844. When the dialyzer 11 is placed between the left support plate 81 and the right support plate 82, the piston rods of the cylinder IV 841 on the left support plate 81 and the right support plate 82 extend, driving the guide cylinder 842 to move toward the middle, thereby driving the vibration spring 843 and the vibration clamping plate 844 to approach the dialyzer 11 together, and the vibration clamping plates 844 on the left and right sides are pressed on the left and right sides of the dialyzer 11 and clamp the dialyzer 11. At this time, the dialyzer vibration motors 845 on the left and right sides are turned on. At the same time, the dialyzer support rotation motor 5 drives the dialyzer 11 to tilt, and the dialyzer 11 is tilted. When the flushing liquid passes through the dialyzer 11, the dialyzer vibration motors 845 on the left support plate 81 and the right support plate 82 are in a high and low position, and the dialyzer support rotating motor 5 rotates to drive the dialyzer 11 to tilt, so that the dialyzer 11 moves in multiple dimensions. Driven by the pre-flushing liquid, the air and impurities attached to the inner wall of the dialyzer 11 and the fibers in the dialyzer 11 can be separated and discharged as soon as possible. After the dialyzer 11 is tilted, it is also beneficial for the gas and impurities attached to the top of the dialyzer 11 to be discharged through the venous end or the arterial end.

[0046] A clamping mechanism 83 is installed on the inner side of the left support plate 81 near the upper and lower sides and the inner side of the right support plate 82 near the upper and lower sides. The clamping mechanism 83 includes a clamping cylinder V 831 and a clamping plate 832. Figure 8 Cylinder V mounting holes 833 are provided on the inner side of the left support plate 81 near the upper and lower sides and on the inner side of the right support plate 82 near the upper and lower sides. Fig. 9 and Fig.10As shown, a clamping cylinder V 831 is installed in each cylinder V mounting hole 833, and the piston rod of the clamping cylinder V 831 faces inward (that is, the piston rod of the clamping cylinder V 831 faces the middle part between the left support plate 81 and the right support plate 82), and the piston rod of the clamping cylinder V 831 is fixedly connected with a clamping plate 832, and the clamping plate 832 is an arc-shaped plate, and the clamping plate 832 on the inner side of the left support plate 81 close to the upper side and the clamping plate 832 on the inner side of the right support plate 82 close to the upper side form a group of dialyzer clamping plates, and the clamping plate 832 on the inner side of the left support plate 81 close to the lower side and the clamping plate 832 on the inner side of the right support plate 82 close to the lower side form another group of dialyzer clamping plates. Before the priming begins, when the dialyzer 11 needs to be turned or tilted, the piston rods of the clamping cylinders V831 on the left support plate 81 and the right support plate 82 extend to drive the clamping plates 832 on the left and right sides to approach the dialyzer 11 and clamp the dialyzer 11. The dialyzer 11 is clamped more stably by the upper and lower sets of dialyzer clamping plates. When the dialyzer 11 is in the formal dialysis, the dialyzer 11 is also clamped by the two sets of dialyzer clamping plates.

[0047] The rear ends of the left support plate 81 and the right support plate 82 are hinged to each other through a positioning rotation mechanism, and the positioning rotation mechanism includes a positioning shaft 85 and a torque spring 86. Fig.11 As shown. At least two inner grooves 87 are provided near the inner side of the rear end of the left support plate 81, and outer convex rotating arms 88 are provided near the inner side of the rear end of the right support plate 82, which are equal to the number of the inner grooves 87 and cooperate with each other. In this embodiment, the number of the inner grooves 87 and the outer convex rotating arms 88 are both two. Through holes Ⅰ89 are provided on the rear end of the left support plate 81 and the outer convex rotating arms 88. The outer convex rotating arms 88 on the rear end of the right support plate 82 are located in the inner groove 87 on the rear end of the corresponding left support plate 81. The positioning shaft 85 passes through the through hole Ⅰ89 on the rear end of the left support plate 81 and the through hole Ⅰ89 on the outer convex rotating arms 88. Torque springs 86 are sleeved on the positioning shaft 85 in each inner groove 87 and at both ends of the corresponding outer convex rotating arms 88. One end of the torque spring 86 is fixedly connected to the side wall of the corresponding inner groove 87, and the other end of the torque spring 86 is fixedly connected to the corresponding outer convex rotating arm 88. When the torque spring 86 is in a natural state, the front end snap-in ends of the left support plate 81 and the right support plate 82 are close to each other. When the dialyzer 11 is installed on the dialyzer support 8, the dialyzer 11 is pressed against the front end snap-in ends of the left support plate 81 and the right support plate 82. After the snap-in end on the right side is pressed, the right support plate 82 rotates to the right rear side around the positioning shaft 85, and the torque spring 86 is deformed. After the dialyzer 11 is placed between the left support plate 81 and the right support plate 82, the restoring force of the torque spring 86 drives the left support plate 81 and the right support plate 82 close to the dialyzer 11, and the clamping mechanism 83 or the vibration mechanism 84 clamps the dialyzer 11.

[0048] The inner sides of the left clamping plate 67, the right clamping plate 75, the vibration clamping plate 844 and the clamping plate 832 are all provided with rubber pads 90, and the inner side surface of each rubber pad 90 is installed with a pressure sensor 91 and an inclination sensor 92, such as Fig.12 As shown. When the left clamping plate 67 and the right clamping plate 75 clamp the cartridge 10, and the clamping plate 832 or the vibrating clamping plate 844 clamps the dialyzer 11, the pressure sensor 91 can monitor the clamping force to prevent the cartridge 10 and the dialyzer 11 from being damaged by excessive clamping force, and to prevent the cartridge 10 from slipping off the left clamping plate 67 and the right clamping plate 75 due to too light clamping force, and to prevent the dialyzer 11 from slipping off the left and right vibrating clamping plates 844 or the left and right clamping plates 832 due to too light clamping force. The tilt sensor 92 can monitor the tilt angle of the cartridge 10 and the dialyzer 11, so that the cartridge 10 and the dialyzer 11 are tilted to the optimal position, which is beneficial for the gas and impurities attached to the top of the cartridge 10 and the dialyzer 11 to move upward and discharge further, and also makes the venous end or arterial end of the cartridge 10 and the dialyzer 11 in the optimal position for discharge.

[0049] The hemoperfusion combined with hemodialysis dialysis machine comprises a dialysis machine body 12 and the above-mentioned hemoperfusion device support device, such as Fig.13 A rectangular cross-sectional snap-in hole 13 is provided on the front side of the dialysis machine body 12 and close to the right side. Fig.14 As shown, each surface of the inner wall of the card hole 13 is provided with a mounting hole 14 corresponding to the card slot 103, and the mounting hole 14 is composed of a circular hole section I with a small diameter close to the inner side and a circular hole section II with a large diameter close to the outer side. A locking mechanism 15 is installed in each mounting hole 14, as shown in FIG. Fig.15 The locking mechanism 15 includes a cylinder VI 151, a fixing plate 152, a guide locking sleeve 153, a locking pin 154, a locking spring 155 and a locking pull rope 156. Fig.16As shown, the cylinder VI 151 is installed in the circular hole segment I, the fixing plate 152 is stuck in the circular hole segment II and is close to the step formed between the circular hole segment I and the circular hole segment II, a guide hole is set in the middle of the fixing plate 152, the guide locking sleeve 153 passes through the guide hole and slides with the guide hole wall, the locking pin 154 is set in the circular hole segment II and slides with the inner wall of the circular hole segment II, the inner side end of the locking pin 154 is fixedly connected with the outer end of the guide locking sleeve 153, and the piston rod of the cylinder VI 151 extends toward the guide locking sleeve 153. The inner end of the sleeve 153, the locking spring 155 is sleeved outside the guide locking sleeve 153 and is located between the locking pin 154 and the fixing plate 152, one end of the locking spring 155 is fixed to the inner end of the locking pin 154, and the other end of the locking spring 155 is fixed to the fixing plate 152, the locking pull rope 156 passes through the guide locking sleeve 153, one end of the locking pull rope 156 is fixedly connected to the inner end of the locking pin 154, and the other end of the locking pull rope 156 is fixedly connected to the piston rod of the cylinder VI 151. The snap-in section 101 is inserted into the snap-in hole 13, and the outer end of the locking pin 154 is inserted into the corresponding snap-in groove 103, as shown in FIG. Fig.15 As shown. The cylinder VI 151 is controlled by the controller in the dialyzer body 12. Before the dialysis pre-flushing machine is installed, the blood perfusion device support device needs to be installed on the dialyzer body 12. The controller in the dialyzer body 12 controls the piston rod of the cylinder VI 151 to retract, and pulls the locking pin 154 to move into the mounting hole 14 through the locking rope 156. The guide locking sleeve 153 slides toward one side of the cylinder VI 151, and the locking spring 155 is compressed. Then, the snap-in section 101 of the mounting base 1 is inserted into the snap-in hole 13. After the insertion, the controller controls the piston rod of the cylinder VI 151 to extend, and the locking rope 156 is loosened. At the same time, under the restoring force of the locking spring 155, the locking spring 155 drives the locking pin 154 to move outward in the mounting hole 14 and insert it into the corresponding card slot 103, so that the blood perfusion device support device is installed on the dialyzer body 12.

[0050] The pressure sensor 91 and the inclination sensor 92 are both electrically connected to the controller in the dialyzer body 12. The right telescopic cylinder I2, the perfusion device support rotating motor 4, the dialyzer bracket rotating motor 5, the left cylinder II 63, the right cylinder III 71, the perfusion device left vibration motor 69, the perfusion device right vibration motor 77, the cylinder IV 841, the dialyzer vibration motor 845, the clamping cylinder V 831 and the cylinder VI 151 are all controlled by the controller in the dialyzer body 12.

[0051] A base 16 is provided on the right side wall of the dialysis machine body 12 near the lower part, and a support arm 17 is provided on the right side wall of the dialysis machine body 12 near the upper part. The base 16 is provided with a socket, and the support arm 17 is provided with a through hole II. The support rod 18 of the infusion stand passes through the through hole II on the support arm 17, and the bottom of the support rod 18 is inserted into the socket on the base 16. Fig.13 and Fig.17The distance between the support center formed by the left support plate 81 and the right support plate 82 and the support rod 18 is greater than half the length of the dialyzer 11, which can prevent the ends of the cartridge 10 and the dialyzer 11 from contacting the support rod 18 and affecting the flipping of the cartridge 10 and the dialyzer 11 when the cartridge support rotating motor 4 drives the cartridge 10 to flip and the dialyzer support rotating motor 5 drives the dialyzer 11 to flip. The piston rod of the right telescopic cylinder I2, the power output shafts of the cartridge support rotating motor 4 and the dialyzer support rotating motor 5 are all facing the right side of the dialyzer body 12. After the piston rod of the right telescopic cylinder I2 is extended, the entire L-shaped bracket 3, the cartridge support rotating motor 4, the dialyzer support rotating motor 5, the cartridge support 6 and the dialyzer support 8 can be driven to be located outside the right side of the dialyzer body 12. This arrangement is beneficial to the L-shaped bracket 3, the cartridge support rotating motor 4, the dialyzer support rotating motor 5, the cartridge support 6, the dialyzer support 8, the cartridge 10 clamped between the left clamping plate 67 and the right clamping plate 75, and the dialyzer 11 clamped between the left and right clamping plates 832 or the left and right vibrating clamping plates 844 to flip or tilt, and can also make the connector on the dialyzer 11 connected to the bypass pipeline always located on the right side of the dialyzer 11, so as to be conveniently connected to the bypass pipeline.

[0052] The left spring 66, the right spring 74 and the vibration spring 843 are all hollow springs. After the power cord passes through the hollow cavity of the left spring 66, one end of the power cord is connected to the power supply in the dialyzer body 12, and the other end of the power cord is connected to the left vibration motor 69 of the perfusion device; after the power cord passes through the hollow cavity of the right spring 74, one end of the power cord is connected to the power supply in the dialyzer body 12, and the other end of the power cord is connected to the right vibration motor 77 of the perfusion device; the power cord passes through the hollow cavity of the vibration spring 843, one end of the power cord is connected to the power supply in the dialyzer body 12, and the other end of the power cord is connected to the dialyzer vibration motor 845 on the corresponding side. The left spring 66, the right spring 74 and the vibration spring 843 with hollow structures are used, and the corresponding power cords are arranged in the hollow structures of the left spring 66, the right spring 74 and the vibration spring 843 to prevent the power cords from being exposed and affecting the clamping and vibration of the perfusion device 10 and the dialyzer 11.

[0053] When using the hemoperfusion combined with hemodialysis dialysis machine, before the dialysis machine is put on, the hemoperfusion device support device needs to be installed on the dialysis machine body 12, and the controller controls the piston rod of the right telescopic cylinder I2 to extend to the right side of the dialysis machine body 12, driving the L-shaped bracket 3, the perfusion device bracket rotating motor 4, the dialyzer bracket rotating motor 5, the perfusion device bracket 6 and the dialyzer bracket 8 to move rightward together, so that the perfusion device bracket 6 and the dialyzer bracket 8 are outside the right side of the dialysis machine body 12; then the dialyzer 11 and the perfusion device 10 are installed on the hemoperfusion device support device, and the installation method is as follows:

[0054] Installation of the dialyzer 11: Insert the dialyzer 11 between the left support plate 81 and the right support plate 82, so that the bypass interface end on the dialyzer 11 faces right, so that it just corresponds to the bypass pipeline on the right side wall of the dialyzer body 12, which is convenient for connecting with the bypass pipeline; the controller controls the piston rod of the clamping cylinder V831 to extend, drive the clamping plate 832 to approach the dialyzer body 12, so that the rubber pads 90 on the inner sides of the clamping plates 832 on the left and right sides are pressed on the left and right sides of the dialyzer 11, and the dialyzer 11 is clamped by the upper and lower sets of dialyzer clamping plates, and the pressure sensor on the rubber pad 90 on the inner side of the clamping plate 832 The device 91 detects the clamping force of the clamping plate 832 on the dialyzer 11, and the size of the clamping force can be controlled; the venous line is then connected to the venous end of the dialyzer 11. After the venous end of the dialyzer 11 is connected, the controller controls the dialyzer bracket rotating motor 5 to rotate, driving the dialyzer 11 to flip, and the venous end of the dialyzer 11 flips forward until the venous end of the dialyzer 11 is located at the bottom of the dialyzer 11, and then the arterial line is connected to the arterial end of the dialyzer 11, and then the dialyzer 11 is driven to rotate by the dialyzer bracket rotating motor 5, so that the venous end of the dialyzer 11 returns to the top.

[0055] Installation of the cartridge 10: The cartridge 10 is placed between the left clamping plate 67 and the right clamping plate 75, and the piston rods of the left cylinder II 63 and the right cylinder III 71 are extended. The piston rod of the left cylinder II 63 extends to drive the left sliding sleeve 65 to drive the left clamping plate 67 to press on the left side of the cartridge 10, and the piston rod of the right cylinder III 71 extends to drive the right sliding sleeve 73 to drive the right clamping plate 75 to press on the right side of the cartridge 10. The venous end of the cartridge 10 faces upward, and the venous line is connected to the venous end of the cartridge 10. After the venous end of the cartridge 10 is connected, the controller controls the cartridge bracket rotating motor 4 to rotate, driving the cartridge 10 to rotate until the arterial end of the cartridge 10 is in a position convenient for installation, and then the arterial line is connected to the arterial end of the cartridge 10, and then the cartridge 10 is driven to rotate by the cartridge bracket rotating motor 4, so that the venous end of the cartridge 10 returns to the top.

[0056] Start pre-flushing the perfusion device 10 and the dialyzer 11 to exhaust gas and remove impurities:

[0057] The irrigator 10 is pre-charged: the piston rods of the left cylinder II 63 and the right cylinder III 71 are retracted a short distance, so that the left sliding sleeve 65 leaves the left clamping plate 67, the right sliding sleeve 73 leaves the right clamping plate 75, and the left pull rope 68 and the right pull rope 76 are in a relaxed state. The left clamping plate 67 presses the left side of the irrigator 10 by the driving force of the left spring 66, and the right clamping plate 75 presses the right side of the irrigator 10 by the driving force of the right spring 74, so that the irrigator 10 is suspended on the U-shaped frame 61 by the left spring 66 and the right spring 74. The left vibration motor 69 and the right vibration motor 77 of the cartridge are turned on, and the priming liquid is poured in. The motor 5 on the cartridge holder drives the cartridge holder 6 to tilt forward or backward, so that the cartridge 10 is in multi-dimensional vibration, so that the gas in the cartridge 10, including the gas and impurities between the solid adsorbents in the cartridge 10, on the solid adsorbents and on the inner wall of the cartridge 10, moves upward in multiple dimensions and is discharged from the top of the cartridge 10, so that the gas and impurities in the cartridge 10 can be discharged efficiently and completely in a short time.

[0058] Pre-flushing the dialyzer 11: the controller controls the piston rod of the cylinder IV 841 to extend, and the piston rod drives the guide cylinder 842 to move toward the middle, thereby driving the vibration spring 843 and the vibration clamp 844 to move closer together, and the rubber pads 90 on the inner side of the left and right vibration clamps 844 are pressed on the left and right sides of the dialyzer 11 and clamp the dialyzer 11. At this time, the controller controls the piston rod of the clamping cylinder V 831 to retract, driving the clamping plate 832 and the rubber pad 90 on its inner side away from the dialyzer 11, and releasing the constraint of the clamping mechanism 83 on the dialyzer 11. The dialyzer vibration motors 845 on the left and right sides are turned on. At the same time, the dialyzer support rotating motor 5 drives the dialyzer 11 to tilt. The tilt angle of the dialyzer 11 is detected by the inclination sensor 92 on the rubber pad 90 on the inner side of the vibration clamp 844, so as to accurately control the tilt angle of the dialyzer 11. When the priming liquid passes through the dialyzer 11, the dialyzer vibration motors 845 of the left support plate 81 and the right support plate 82 are in a high and low position, and the dialyzer support rotating motor 5 rotates to drive the dialyzer 11 to tilt, so that the dialyzer 11 is in a multi-dimensional mixed motion. Driven by the priming liquid, the inner wall of the dialyzer 11 and the fibers in the dialyzer 11 are attached to the dialyzer 11. Air and impurities can be separated and discharged as quickly as possible, and after the dialyzer 11 is tilted, it is also convenient for the gas and impurities attached to the top of the dialyzer 11 to be discharged through the venous end. After the gas and impurities in the dialyzer 11 membrane are discharged, the bypass interface on the dialyzer 11 is connected to the bypass pipeline accordingly, and the controller controls the dialyzer bracket rotation motor 5 to drive the dialyzer 11 to flip, so that the arterial end of the dialyzer 11 is higher than the venous end, and the bypass pipeline is opened to flush the outside of the dialyzer 11 membrane. At the same time, the two dialyzer vibration motors 845 are turned on, and the dialyzer bracket rotation motor 5 drives the dialyzer 11 to swing up and down slightly, so that the gas and impurities outside the dialyzer 11 membrane can be quickly discharged.

[0059] The hemoperfusion combined with hemodialysis dialysis machine realizes automatic flipping of the perfusion device 10 and the dialyzer 11, automatic tilting of the perfusion device 10 and the dialyzer 11, and automatic vibration of the perfusion device 10 and the dialyzer 11, thereby realizing automatic exhaust and impurity removal in the perfusion device 10 and the dialyzer 11, without manual operation, and the medical staff only needs to connect the venous end, the arterial end and the bypass interface, which greatly reduces the manual operation, thereby reducing the probability of contact with the instrument, and reducing the risk of infection caused by the subsequent manual operation of the arteriovenous puncture needle connector of the human body. At the same time, through automatic control, the perfusion device 10 and the dialyzer 11 can be pre-flushed to exhaust and remove impurities synchronously, which not only saves time, but also avoids the risk of embolism caused by the improper operation of the medical staff, which affects the impurities in the perfusion device 10 and the dialyzer and the gas inside and outside the dialyzer membrane cannot be completely exhausted, greatly reducing the dependence on medical staff, so that the exhaustion of gas and impurities in the pre-flushing perfusion device 10 and inside and outside the membrane of the dialyzer 3 is better guaranteed.

[0060] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the purpose and scope of the technical solution of the present invention, which should be included in the scope of the claims of the present invention.

Claims

1. A blood perfusion device support device, characterized in that: The device comprises a mounting base (1), a right telescopic cylinder I (2), an L-shaped bracket (3), a perfusion device bracket rotating motor (4), a dialyzer bracket rotating motor (5), a perfusion device bracket (6) and a dialyzer bracket (8); the right telescopic cylinder I (2) is fixedly connected to the mounting base (1), the piston rod of the right telescopic cylinder I (2) extends horizontally to the right, the L-shaped bracket (3) is fixedly connected to the piston rod of the right telescopic cylinder I (2), and the dialyzer bracket rotating motor (5) is fixedly installed on the top of the L-shaped bracket (3). The power output shaft of the dialyzer support rotating motor (5) extends to the right, the dialyzer support (8) is mounted on the power output shaft of the dialyzer support rotating motor (5), the bottom of the L-shaped support (3) extends to the right from the bottom of the dialyzer support (8), the cartridge support rotating motor (4) is fixedly mounted on the right end of the bottom of the L-shaped support (3), the power output shaft of the cartridge support rotating motor (4) extends to the right, and the cartridge support (6) is mounted on the power output shaft of the cartridge support rotating motor (4); The perfusion device support (6) comprises a U-shaped frame (61), a left perfusion device support frame and a right perfusion device support frame; the left middle portion of the U-shaped frame (61) is fixedly connected to the power output shaft of the perfusion device support rotating motor (4); the left perfusion device support frame is mounted on the left top end of the U-shaped frame (61); the right perfusion device support frame is mounted on the right top end of the U-shaped frame (61); and the left perfusion device support frame and the right perfusion device support frame are symmetrically arranged on the U-shaped frame (61); The left support frame of the irrigator comprises a left guide sleeve (62), a left cylinder II (63), a left guide plate (64), a left sliding sleeve (65), a left spring (66), a left clamping plate (67), a left pull rope (68) and a left vibration motor (69) of the irrigator; the left guide sleeve (62) is fixed on the left top end of the U-shaped frame (61), the open end of the left guide sleeve (62) faces right, the left cylinder II (63) is installed on the left side of the left guide sleeve (62), the left guide plate (64) is fixedly arranged on the cross section of the left guide sleeve (62), the left sliding sleeve (65) passes through the through hole arranged in the middle of the left guide plate (64) and is slidably matched with the left guide plate (64), and the left The left end of the sliding sleeve (65) is fixedly connected to the piston rod of the left cylinder II (63), the left spring (66) is sleeved on the left sliding sleeve (65), the left end of the left spring (66) is fixed on the left guide plate (64), the right end of the left spring (66) extends out of the right end of the left guide sleeve (62) and is fixedly connected to the left clamping plate (67), the left pull rope (68) passes through the left sliding sleeve (65), the left end of the left pull rope (68) is fixedly connected to the piston rod of the left cylinder II (63), the right end of the left pull rope (68) is fixedly connected to the left side of the left clamping plate (67), and the left vibration motor (69) of the irrigator is fixedly installed on the left side of the left clamping plate (67) near the bottom or near the top.

2. The blood perfusion device support device according to claim 1, characterized in that: The right support frame of the irrigator comprises a right guide sleeve (70), a right cylinder III (71), a right guide plate (72), a right sliding sleeve (73), a right spring (74), a right clamping plate (75), a right pull rope (76) and a right vibration motor (77) of the irrigator; the right guide sleeve (70) is fixed on the top right side of the U-shaped frame (61), the open end of the right guide sleeve (70) faces left, the right cylinder III (71) is installed on the right side of the right guide sleeve (70), the right guide plate (72) is fixedly arranged on the cross section of the right guide sleeve (70), the right sliding sleeve (73) passes through the through hole arranged in the middle of the right guide plate (72) and is slidably matched with the right guide plate (72), and the right end of the right sliding sleeve (73) is fixedly connected to the piston rod of the right cylinder III (71). The right spring (74) is sleeved on the right sliding sleeve (73), the right end of the right spring (74) is fixed on the right guide plate (72), the left end of the right spring (74) extends out of the left end of the right guide sleeve (70) and is fixedly connected to the right clamping plate (75), the right pull rope (76) passes through the right sliding sleeve (73), the right end of the right pull rope (76) is fixedly connected to the piston rod of the right cylinder III (71), the left end of the right pull rope (76) is fixedly connected to the right side of the right clamping plate (75), and the right vibration motor (77) of the irrigator is fixedly installed on the right side of the right clamping plate (75) near the bottom or near the top; the left clamping plate (67) and the right clamping plate (75) are both arc-shaped plates, and the concave arc-shaped surfaces of the left clamping plate (67) and the right clamping plate (75) correspond to each other.

3. The blood perfusion device support device according to claim 2, characterized in that: The right end of the left sliding sleeve (65) is provided with an inwardly concave arc-shaped end (78) which can be fitted with the left outer wall of the left clamping plate (67), and the left end of the right sliding sleeve (73) is provided with an inwardly concave arc-shaped end (78) which can be fitted with the right outer wall of the right clamping plate (75); and a semicircular frame (611) bent backward is provided near the middle of the bottom of the U-shaped frame (61).

4. The blood perfusion device support device according to claim 3, characterized in that: The dialyzer support (8) comprises a left support plate (81) and a right support plate (82); the left support plate (81) and the right support plate (82) are both arc-shaped plates, the inner concave arc-shaped surfaces of the left support plate (81) and the right support plate (82) correspond to each other, the rear ends of the left support plate (81) and the right support plate (82) are hinged to each other, the front ends of the left support plate (81) and the right support plate (82) form a clamping end of the dialyzer (11), and the power output shaft of the dialyzer support rotating motor (5) is fixedly connected to the left side surface of the left support plate (81); the left support plate (81) and the right support plate (82) are provided with a clamping mechanism (83) for clamping the dialyzer (11) and a vibration mechanism (84) for vibrating the dialyzer (11).

5. The blood perfusion device support device according to claim 4, characterized in that: The vibration mechanism (84) comprises a left vibration mechanism installed at the middle of the inner side of the left support plate (81) and a right vibration mechanism installed at the middle of the inner side of the right support plate (82). The left vibration mechanism and the right vibration mechanism both comprise a cylinder IV (841), a guide tube (842) with an open end, a vibration spring (843), a vibration clamp (844) and a dialyzer vibration motor (845). The middle of the left support plate (81) and the right support plate (82) are both provided with a cylinder IV mounting hole (846). The left cylinder IV (841) is fixedly installed in the cylinder IV mounting hole (846) of the left support plate (81), and the right cylinder IV (841) is fixedly installed in the cylinder IV mounting hole (846) of the right support plate (82). The piston rod of the cylinder IV (841) faces inward, and the guide tube (842) is fixedly connected to the cylinder IV (841). 1), one end of the vibration spring (843) is fixedly connected to the inner end wall of the guide cylinder (842), the other end of the vibration spring (843) extends out of the open end of the guide cylinder (842) and is fixedly connected to the vibration clamping plate (844), the outer diameter of the guide cylinder (842) is smaller than the inner diameter of the cylinder IV mounting hole (846), the vibration clamping plate (844) is an arc-shaped plate, the concave arc-shaped surfaces of the left vibration clamping plate (844) and the right vibration clamping plate (844) correspond to each other, and the left vibration clamping plate (844) and the right vibration clamping plate (844) are used to clamp the dialyzer (11) during vibration, the left dialyzer vibration motor (845) is installed at the left bottom of the left vibration clamping plate (844), and the right dialyzer vibration motor (845) is installed at the right top of the right vibration clamping plate (844).

6. The blood perfusion device support device according to claim 5, characterized in that: A clamping mechanism (83) is installed on the inner side of the left support plate (81) near the upper and lower sides and on the inner side of the right support plate (82) near the upper and lower sides. The clamping mechanism (83) includes a clamping cylinder V (831) and a clamping plate (832). Cylinder V mounting holes (833) are provided on the inner side of the left support plate (81) near the upper and lower sides and on the inner side of the right support plate (82) near the upper and lower sides. A clamping cylinder V (831) is installed in each cylinder V mounting hole (833). The clamping cylinder V (831) ) faces inward, and the piston rod of the clamping cylinder V (831) is fixedly connected with a clamping plate (832), wherein the clamping plate (832) is an arc-shaped plate. The inner side of the left support plate (81) close to the upper clamping plate (832) and the inner side of the right support plate (82) close to the upper clamping plate (832) form a group of dialyzer clamping plates, and the inner side of the left support plate (81) close to the lower clamping plate (832) and the inner side of the right support plate (82) close to the lower clamping plate (832) form another group of dialyzer clamping plates.

7. The blood perfusion device support device according to claim 6, characterized in that: The rear ends of the left support plate (81) and the right support plate (82) are hinged to each other through a positioning and rotating mechanism, and the positioning and rotating mechanism includes a positioning shaft (85) and a torque spring (86). The rear end of the left support plate (81) is provided with at least two inner grooves (87) near the inner side, and the rear end of the right support plate (82) is provided with an outer convex rotating arm (88) whose number is equal to the inner grooves (87) and which cooperates with each other. The rear end of the left support plate (81) and the outer convex rotating arm (88) are both provided with a through hole I (89). The outer convex rotating arm (88) on the rear end of the right support plate (82) is located on the rear end of the corresponding left support plate (81). In the inner groove (87), the positioning shaft (85) passes through the through hole I (89) on the rear end of the left support plate (81) and the through hole I (89) on the outer convex rotating arm (88). Torque springs (86) are sleeved on the positioning shaft (85) in each inner groove (87) and at both ends of the corresponding outer convex rotating arm (88). One end of the torque spring (86) is fixedly connected to the side wall of the corresponding inner groove (87), and the other end of the torque spring (86) is fixedly connected to the corresponding outer convex rotating arm (88). When the torque spring (86) is in a natural state, the snap-in ends of the front ends of the left support plate (81) and the right support plate (82) are close to each other.

8. The blood perfusion device support device according to claim 7, characterized in that: The inner sides of the left clamping plate (67), the right clamping plate (75), the vibration clamping plate (844) and the clamping plate (832) are all provided with rubber pads (90), and the inner side surface of each rubber pad (90) is installed with a pressure sensor (91) and an inclination sensor (92).

9. A hemoperfusion combined with hemodialysis dialysis machine, comprising a dialysis machine body (12), characterized in that: It also includes the blood perfusion device support device according to claim 8; the mounting base (1) includes a snap-in section (101) and an external section (102), the cross section of the snap-in section (101) is a rectangular structure, and the four faces of the snap-in section (101) are provided with snap-in slots (103); a snap-in hole (13) with a rectangular cross section is provided on the front side and close to the right side of the dialysis machine body (12), and each face of the inner wall of the snap-in hole (13) is provided with a mounting hole (14) corresponding to the snap-in slot (103), and the mounting hole (14) is formed by the snap-in hole (13) close to the inner side. The mounting hole (14) is composed of a circular hole section I with a small diameter and a circular hole section II with a large diameter close to the outside, and a locking mechanism (15) is installed in each mounting hole (14); the locking mechanism (15) comprises a cylinder VI (151), a fixing plate (152), a guide locking sleeve (153), a locking pin (154), a locking spring (155) and a locking pull rope (156); the cylinder VI (151) is installed in the circular hole section I, the fixing plate (152) is stuck in the circular hole section II and is close to the step formed between the circular hole section I and the circular hole section II, and the fixing plate (152) A guide hole is provided in the middle of the guide locking sleeve (153), the guide locking sleeve (153) passes through the guide hole and slides with the guide hole, the locking pin (154) is provided in the circular hole section II and slides with the inner wall of the circular hole section II, the inner end of the locking pin (154) is fixedly connected to the outer end of the guide locking sleeve (153), the piston rod of the cylinder VI (151) extends to the inner end of the guide locking sleeve (153), the locking spring (155) is sleeved outside the guide locking sleeve (153) and is located between the locking pin (154) and the fixing plate (152), the locking spring (155) is sleeved outside the guide locking sleeve (153) and is located between the locking pin (154) and the fixing plate (152), and the locking spring (15 5) is fixed to the inner end of the locking pin (154), the other end of the locking spring (155) is fixed to the fixing plate (152), the locking rope (156) passes through the guide locking sleeve (153), one end of the locking rope (156) is fixedly connected to the inner end of the locking pin (154), and the other end of the locking rope (156) is fixedly connected to the piston rod of the cylinder VI (151); the snap-in section (101) is inserted into the snap-in hole (13), and the outer end of the locking pin (154) is inserted into the corresponding snap-in groove (103).

10. The hemoperfusion combined with hemodialysis dialysis machine according to claim 9, characterized in that: The pressure sensor (91) and the tilt sensor (92) are both electrically connected to the controller in the dialyzer body (12); the right telescopic cylinder I (2), the perfusion device support rotating motor (4), the dialyzer bracket rotating motor (5), the left cylinder II (63), the right cylinder III (71), the perfusion device left vibration motor (69), the perfusion device right vibration motor (77), the cylinder IV (841), the dialyzer vibration motor (845), the clamping cylinder V (831) and the cylinder VI (151) are all controlled by the controller in the dialyzer body (12).

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