Polypeptide purification equipment for food production

By designing a polypeptide purification device including a spoiler, a flip part, a vibrating spring and a cleaning mechanism, the problem of impurity accumulation in existing equipment affecting purification efficiency is solved, and more efficient polypeptide purification and automated cleaning are achieved.

CN119951333AInactive Publication Date: 2025-05-09YANTAI UNIV
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Patent Information

Application Number
CN202510439960.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-09
Publication Date
2025-05-09
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

After long-term use of existing peptide purification equipment, impurities accumulate on the ultrafiltration membrane and nanofiltration membrane, affecting the purification efficiency of the peptide.

Method used

A polypeptide purification device for food production is designed, including a separation tank, a control device, a spoiler, a driving part, a flip part, an auxiliary part, a separation part and a cleaning mechanism. By setting up a spoiler to increase the contact area between the polypeptide solution and the membrane, the flipped part and vibrating spring are used to achieve vibration and cleaning of the membrane, and the cleaning mechanism automatically sprays the cleaning liquid to clean the membrane.

Benefits of technology

It improves the purification efficiency of the peptide purification equipment, reduces the need for manual cleaning, and enhances the automation and efficiency of the equipment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses polypeptide purification equipment for food production, and relates to the technical field of separation and purification, the polypeptide purification equipment comprises a separation tank and a control device, a partition plate is arranged in the separation tank and divides the interior of the separation tank into a first separation chamber and a second separation chamber, a liquid inlet pipe is arranged on the separation tank, and a first liquid feeding hopper is arranged on the liquid inlet pipe; a communicating pipe is fixedly arranged on the partition plate, a first liquid receiving hopper is arranged on the communicating pipe, a second liquid feeding hopper is arranged on the communicating pipe, and a second liquid receiving hopper is arranged on the liquid outlet pipe; the device further comprises a spoiler, a driving part arranged on the separation tank, an overturning part arranged on the driving part, auxiliary parts arranged in the first separation chamber and the second separation chamber, a separation part arranged on the overturning part and a cleaning mechanism arranged on the separation tank. According to the device, the cleaning mechanism is arranged, so that the device can clean an ultrafiltration membrane, workers do not need to manually clean the ultrafiltration membrane, and the polypeptide purification efficiency of the device is improved to a certain extent.
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Description

Technical Field

[0001] The invention relates to the technical field of separation and purification, and in particular to a polypeptide purification device for food production. Background Art

[0002] As people's demand for healthy food increases, the market for functional food and health products is developing rapidly. Among them, peptides, as an important bioactive ingredient, play a significant role in enhancing immunity and promoting metabolism. However, after a long period of operation, the impurities filtered out by the ultrafiltration membrane and nanofiltration membrane in the current peptide purification equipment accumulate on the surface of the ultrafiltration membrane and nanofiltration membrane, which greatly affects the purification efficiency of the purification equipment for peptides in peptide solutions. Therefore, improvement is urgently needed. Summary of the invention

[0003] In view of the shortcomings of the prior art, the purpose of the present invention is to provide a polypeptide purification device for food production, aiming to solve the above technical problems.

[0004] In order to achieve the above object, the present invention adopts the following technical solutions: A polypeptide purification device for food production, comprising a separation tank and a control device, wherein a partition is fixedly arranged in the separation tank, and the partition divides the interior of the separation tank into a first separation chamber and a second separation chamber, and a liquid inlet pipe connected to the interior of the first separation chamber is fixedly arranged on the separation tank, and a first liquid feeding hopper is fixedly arranged at one end of the liquid inlet pipe located in the first separation chamber, and a first valve body for controlling the opening and closing of the liquid inlet pipe is arranged on the liquid inlet pipe, and the first valve body is electrically connected to the control device, and a connecting pipe is fixedly arranged on the partition, and the connecting pipe is located at the first separation chamber. A first liquid receiving hopper is fixedly arranged at one end, the axis of the first liquid receiving hopper coincides with the axis of the first liquid delivery hopper, a sealing sleeve is provided on the outside of the connecting pipe for preventing the liquid in the first separation chamber from entering the second separation chamber, a second liquid delivery hopper is fixedly arranged at one end of the connecting pipe located in the second separation chamber, a liquid outlet pipe communicating with the interior of the second separation chamber is fixedly arranged on the separation tank, a second liquid receiving hopper is fixedly arranged at one end of the liquid outlet pipe located in the second separation chamber, and the axis of the second liquid receiving hopper coincides with the axis of the second liquid delivery hopper, the polypeptide purification equipment for food production also includes: There are two groups of spoilers, and the two groups of spoilers are respectively arranged on the inner surface of the first liquid feeding hopper and the inner surface of the second liquid feeding hopper, and the spoilers are evenly spaced on the inner surface of the first liquid feeding hopper and the inner surface of the second liquid feeding hopper; A driving part, comprising two groups, and the two groups of driving parts are symmetrically arranged on the separation tank, and the driving part is electrically connected to the control device; The turning part is arranged on the driving part, and the driving part is provided with four groups of turning parts, and the four groups of turning parts are evenly distributed on the driving part; The auxiliary parts have two groups, and the two groups of auxiliary parts are respectively arranged in the first separation chamber and the second separation chamber; A separation portion, disposed on the flip portion; The cleaning mechanism is arranged on the separation tank, and the cleaning mechanism is electrically connected to the control device.

[0005] Preferably, the driving unit comprises: A rotating motor is fixedly mounted on the separation tank and electrically connected to the control device; A rotating shaft is rotatably disposed on the separation tank, and one end of the rotating shaft close to the rotating motor is fixedly connected to the output end of the rotating motor; A rotating seat, fixedly arranged at one end of the rotating shaft away from the rotating motor; The connecting plate is fixedly arranged on the rotating seat, and the rotating seat is provided with four evenly distributed connecting plates.

[0006] Preferably, the turning portion comprises: A turning shaft, rotatably disposed on the connecting plate; A rotating gear is fixedly arranged on the flip shaft; A connecting seat, fixedly arranged at one end of the flip shaft away from the connecting plate; A connecting frame, fixedly arranged on the connecting seat; A longitudinal rod, fixedly disposed in the connecting frame; A vibration spring is sleeved on the longitudinal rod, and two vibration springs are sleeved on the longitudinal rod, and ends of the two vibration springs that are away from each other are fixedly connected to the connection frame.

[0007] Preferably, the auxiliary part comprises: The vertical block located in the first separation chamber is fixedly connected to the partition, and two symmetrically arranged vertical blocks are arranged in the first separation chamber, and the vertical block located in the second separation chamber is fixedly connected to the separation tank, and two symmetrically arranged vertical blocks are arranged in the second separation chamber; The arc-shaped tooth plate is fixedly arranged on the vertical block, and the circumference of the arc-shaped tooth plate is equal to half of the circumference of the rotating gear. The arc-shaped tooth plate is used to mesh with the adjacent rotating gear to drive the flip shaft to rotate half a circle.

[0008] Preferably, the separation unit comprises: A vibration block is slidably disposed on the longitudinal rod, and the vibration block is fixedly connected to an adjacent vibration spring, and the vibration spring is in a compressed state; The separation cover is fixedly arranged on the vibration block, and the height of the separation cover is equal to the distance between the first liquid feeding hopper and the first liquid receiving hopper, and the distance between the first liquid feeding hopper and the first liquid receiving hopper is equal to the distance between the second liquid feeding hopper and the second liquid receiving hopper.

[0009] Preferably, an ultrafiltration membrane for removing macromolecular impurities is fixedly installed on the separation cover in the first separation chamber, and a nanofiltration membrane for concentrating the polypeptide solution is fixedly installed on the separation cover in the second separation chamber.

[0010] Preferably, the cleaning mechanism comprises: There are two main pipelines, and the two main pipelines are respectively connected with the interior of the first separation chamber and the interior of the second separation chamber; A second valve body, disposed on the main pipeline and electrically connected to the control device, the second valve body being used to control the opening and closing of the main pipeline; A branch pipeline is arranged on the main pipeline and communicated with the main pipeline; The liquid spraying parts have three groups, and one group of liquid spraying parts is arranged on the main pipeline, and the other two groups are symmetrically arranged on the branch pipelines.

[0011] Preferably, the liquid spraying portion comprises: A liquid spray pipe, the liquid spray pipe arranged in the liquid spray part on the branch pipe is connected to the branch pipe, and the liquid spray pipe arranged in the liquid spray part on the main pipe is connected to the main pipe; A spray head is arranged on the spray pipe and is connected with the spray pipe. The spray head is used for spraying cleaning liquid downward to clean the ultrafiltration membrane and the nanofiltration membrane.

[0012] Preferably, infrared sensors are provided in the first separation chamber and the second separation chamber, the infrared sensors are electrically connected to the control device, and the infrared sensors are used to locate whether the separation cover is rotated to directly below the spray head.

[0013] Preferably, the separation tank is provided with two sets of drainage parts, and the drainage parts include: A liquid discharge pipe is arranged on the separation tank, and the liquid discharge pipes in the two groups of liquid discharge parts are respectively connected with the interior of the first separation chamber and the interior of the second separation chamber; The third valve body is arranged on the liquid discharge pipe and is electrically connected to the control device. The third valve body is used to control the opening and closing of the liquid discharge pipe.

[0014] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are: 1. The device is provided with a cleaning mechanism, so that the device can clean the ultrafiltration membrane, thereby eliminating the need for staff to manually clean the ultrafiltration membrane, thereby improving the purification efficiency of the device for polypeptides to a certain extent.

[0015] 2. By providing a vibration spring, when the cleaning liquid is sprayed from the nozzle and falls on the ultrafiltration membrane below, the impact of the cleaning liquid on the ultrafiltration membrane causes the separation cover to vibrate, thereby facilitating the removal of large molecular impurities from the ultrafiltration membrane, thereby further improving the cleaning effect of the device on the ultrafiltration membrane, and thus improving the subsequent filtration and purification effect of the ultrafiltration membrane to a certain extent.

[0016] 3. By providing a turning part, the ultrafiltration membrane to be cleaned can be rotated 180 degrees during the process of being transferred to the bottom of the nozzle, so that the subsequent cleaning mechanism can remove the macromolecular impurities on the ultrafiltration membrane.

[0017] 4. The device is provided with a spoiler, so that when the polypeptide solution in the first liquid feeding hopper flows into the first liquid receiving hopper and the polypeptide solution in the second liquid feeding hopper flows into the second liquid receiving hopper, the polypeptide solution can collide with the spoiler, so that the polypeptide solution is dispersed and scattered in the ultrafiltration membrane and nanofiltration membrane below, thereby increasing the contact area between the polypeptide solution and the ultrafiltration membrane and the nanofiltration membrane, thereby improving the purification efficiency of the polypeptide solution of the device to a certain extent. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0019] Figure 1 The present invention shows a three-dimensional structural schematic diagram of a polypeptide purification device for food production.

[0020] Figure 2 A front view of a polypeptide purification device for food production is shown.

[0021] Figure 3 Shows Figure 2 Sectional view of AA.

[0022] Figure 4 A right side view of a polypeptide purification device for food production is shown.

[0023] Figure 5 Shows Figure 4 Cross-sectional view of BB.

[0024] Figure 6 The figure shows the internal structure of a polypeptide purification device for food production.

[0025] Figure 7A partial structural schematic diagram of a polypeptide purification device for food production is shown.

[0026] Figure 8 An exploded view of a part of the structure of a polypeptide purification device for food production is shown.

[0027] Fig. 9 A partial structural schematic diagram of the turning part and the cleaning mechanism is shown.

[0028] Fig.10 An exploded view of the turning part, the auxiliary part and the separating part is shown.

[0029] Legend: 1. Separation tank; 2. Control device; 3. Partition plate; 4. First separation chamber; 5. Second separation chamber; 6. Liquid inlet pipe; 7. First liquid delivery hopper; 8. First valve body; 9. Connecting pipe; 10. First liquid receiving hopper; 11. Sealing sleeve; 12. Second liquid delivery hopper; 13. Liquid outlet pipe; 14. Second liquid receiving hopper; 15. Spoiler; 16. Rotating motor; 17. Rotating shaft; 18. Rotating seat; 19. Connecting plate; 20. Flip shaft; 21. Rotating gear; 22. Connecting seat; 23. Connecting frame; 24. Longitudinal rod; 25. Vibration spring; 26. Vertical block; 27. Arc tooth plate; 28. Vibration block; 29. ​​Separation cover; 30. Ultrafiltration membrane; 31. Nanofiltration membrane; 32. Main pipeline; 33. Second valve body; 34. Branch pipeline; 35. Spray pipe; 36. Spray head; 37. Infrared sensor; 38. Drain pipe; 39. Third valve body. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] In the description of the present invention, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside" and "outside" etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0032] It should be noted that when a component is referred to as being "fixed to" another component, it may be directly on the other component or there may also be a component centered. When a component is considered to be "connected to" another component, it may be directly connected to the other component or there may also be a component centered. When a component is considered to be "set on" another component, it may be directly set on the other component or there may also be a component centered. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are for illustrative purposes only.

[0033] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0034] Reference Figures 1 to 10 The present invention further describes an embodiment of a polypeptide purification device for food production.

[0035] A polypeptide purification device for food production, comprising a separation tank 1 and a control device 2, wherein a partition 3 is fixedly arranged inside the separation tank 1, and the partition 3 divides the interior of the separation tank 1 into a first separation chamber 4 and a second separation chamber 5, and a liquid inlet pipe 6 connected to the interior of the first separation chamber 4 is fixedly arranged on the separation tank 1, and a first liquid feeding hopper 7 is fixedly arranged at one end of the liquid inlet pipe 6 located at the first separation chamber 4, and a first valve body 8 for controlling the opening and closing of the liquid inlet pipe 6 is arranged on the liquid inlet pipe 6, and the first valve body 8 is electrically connected to the control device 2, and a connecting pipe 9 is fixedly arranged on the partition 3, and the connecting pipe 9 is located at one end of the first separation chamber 4. A first liquid receiving hopper 10 is fixedly provided, and the axis of the first liquid receiving hopper 10 coincides with the axis of the first liquid delivery hopper 7. A sealing sleeve 11 is provided on the outside of the connecting pipe 9 for preventing the liquid in the first separation chamber 4 from entering the second separation chamber 5. A second liquid delivery hopper 12 is fixedly provided at one end of the connecting pipe 9 located in the second separation chamber 5. A liquid outlet pipe 13 communicating with the inside of the second separation chamber 5 is fixedly provided on the separation tank 1. A second liquid receiving hopper 14 is fixedly provided at one end of the liquid outlet pipe 13 located in the second separation chamber 5. The axis of the second liquid receiving hopper 14 coincides with the axis of the second liquid delivery hopper 12. The polypeptide purification device for food production also includes: There are two groups of spoilers 15, and the two groups of spoilers 15 are respectively arranged on the inner surface of the first liquid feeding hopper 7 and the inner surface of the second liquid feeding hopper 12, and the spoilers 15 are evenly spaced on the inner surface of the first liquid feeding hopper 7 and the inner surface of the second liquid feeding hopper 12; It should be noted that the device is provided with a spoiler 15, so that when the polypeptide solution in the first liquid feeding hopper 7 flows into the first liquid receiving hopper 10 and the polypeptide solution in the second liquid feeding hopper 12 flows into the second liquid receiving hopper 14, the polypeptide solution can collide with the spoiler 15, so that the polypeptide solution is dispersed and scattered in the ultrafiltration membrane 30 and the nanofiltration membrane 31 below, thereby increasing the contact area between the polypeptide solution and the ultrafiltration membrane 30 and the nanofiltration membrane 31, thereby improving the purification efficiency of the polypeptide solution of the device to a certain extent.

[0036] Reference Figures 1 to 10 , a driving part, having two groups, and the two groups of driving parts are symmetrically arranged on the separation tank 1, and the driving part is electrically connected to the control device 2; The driving unit comprises: A rotating motor 16 is fixedly mounted on the separation tank 1 and electrically connected to the control device 2; A rotating shaft 17 is rotatably disposed on the separation tank 1, and one end of the rotating shaft 17 close to the rotating motor 16 is fixedly connected to the output end of the rotating motor 16; The rotating seat 18 is fixedly disposed at one end of the rotating shaft 17 away from the rotating motor 16; The connecting plate 19 is fixedly disposed on the rotating seat 18 , and the rotating seat 18 is provided with four evenly distributed connecting plates 19 .

[0037] The turning part is arranged on the driving part, and the driving part is provided with four groups of turning parts, and the four groups of turning parts are evenly distributed on the driving part; The turning part comprises: A turning shaft 20 is rotatably disposed on the connecting plate 19; A rotating gear 21 is fixedly disposed on the flip shaft 20; A connecting seat 22, fixedly disposed at one end of the flip shaft 20 away from the connecting plate 19; A connecting frame 23 is fixedly disposed on the connecting seat 22; A longitudinal rod 24, fixedly disposed in the connecting frame 23; The vibration spring 25 is sleeved on the longitudinal rod 24 , and two vibration springs 25 are sleeved on the longitudinal rod 24 , and ends of the two vibration springs 25 that are away from each other are fixedly connected to the connection frame 23 .

[0038] Reference Figures 1 to 10, when the cleaning liquid sprayed by the nozzle 36 falls on the ultrafiltration membrane 30 below, due to the impact of the cleaning liquid on the ultrafiltration membrane 30, the vibration block 28 fixedly connected to the separation cover 29 slides on the longitudinal rod 24, and the setting of the vibration spring 25 enables the vibration block 28 to slide back and forth on the longitudinal rod 24, thereby realizing that the separation cover 29 fixedly connected to the vibration block 28 drives the ultrafiltration membrane 30 to vibrate, thereby facilitating the large molecular impurities to fall off from the ultrafiltration membrane 30; it should be noted that, by providing the vibration spring 25, when the cleaning liquid is sprayed from the nozzle 36 and falls on the ultrafiltration membrane 30 below, the impact of the cleaning liquid on the ultrafiltration membrane 30 enables the separation cover 29 to vibrate, thereby facilitating the large molecular impurities to fall off from the ultrafiltration membrane 30, thereby further improving the cleaning effect of the device on the ultrafiltration membrane 30, and then to a certain extent improving the subsequent filtration and purification effect of the ultrafiltration membrane 30.

[0039] Reference Figures 1 to 10 , the auxiliary part has two groups, and the two groups of auxiliary parts are respectively arranged in the first separation chamber 4 and the second separation chamber 5; The auxiliary part includes: The vertical block 26, the vertical block 26 located in the first separation chamber 4 is fixedly connected to the partition 3, and two symmetrically arranged vertical blocks 26 are provided in the first separation chamber 4, and the vertical block 26 located in the second separation chamber 5 is fixedly connected to the separation tank 1, and two symmetrically arranged vertical blocks 26 are provided in the second separation chamber 5; The arc-shaped tooth plate 27 is fixedly disposed on the vertical block 26 , and the circumference of the arc-shaped tooth plate 27 is equal to half the circumference of the rotating gear 21 . The arc-shaped tooth plate 27 is used to mesh with the adjacent rotating gear 21 to drive the flip shaft 20 to rotate half a circle.

[0040] A separation portion, disposed on the flip portion; The separation unit comprises: A vibration block 28 is slidably disposed on the longitudinal rod 24, and the vibration block 28 is fixedly connected to an adjacent vibration spring 25, and the vibration spring 25 is in a compressed state; The separation cover 29 is fixedly mounted on the vibration block 28, and the height of the separation cover 29 is equal to the distance between the first liquid feeding hopper 7 and the first liquid receiving hopper 10, and the distance between the first liquid feeding hopper 7 and the first liquid receiving hopper 10 is equal to the distance between the second liquid feeding hopper 12 and the second liquid receiving hopper 14.

[0041] An ultrafiltration membrane 30 for removing macromolecular impurities is fixedly disposed on the separation cover 29 in the first separation chamber 4 , and a nanofiltration membrane 31 for concentrating the polypeptide solution is fixedly disposed on the separation cover 29 in the second separation chamber 5 .

[0042] Reference Figures 1 to 10When the ultrafiltration membrane 30 needs to be replaced and cleaned after being used for a period of time, the process is as follows: the first valve body 8 is controlled to be closed by the control device 2, and then the rotary motor 16 close to the first valve body 8 is controlled to start by the control device 2, so that the rotating shaft 17 fixedly connected to the output end of the rotary motor 16 rotates, so that the rotating seat 18 fixedly connected to the rotating shaft 17 rotates, and then the connecting plate 19 arranged on the rotating seat 18 rotates around the axis of the rotating seat 18, thereby driving the flip shaft 20 rotatably connected to the connecting plate 19 Rotating around the axis of the rotating seat 18, the connecting seat 22 fixedly connected to the flip shaft 20 rotates around the axis of the rotating seat 18, driving the connecting frame 23 fixedly connected to the connecting seat 22 to rotate around the axis of the rotating seat 18, so that the longitudinal rod 24 arranged in the connecting frame 23 rotates around the axis of the rotating seat 18, driving the vibration block 28 slidably connected to the longitudinal rod 24 to rotate around the axis of the rotating seat 18, so that the separation cover 29 fixedly connected to the vibration block 28 rotates around the axis of the rotating seat 18, so that the ultrafiltration membrane 30 to be cleaned is rotated out; In the process of the ultrafiltration membrane 30 to be cleaned rotating toward the bottom of the nozzle 36, in the process of the rotating gear 21 meshing with the arc-shaped toothed plate 27, the rotating gear 21 is rotated, and then the flip shaft 20 fixedly connected to the rotating gear 21 rotates around the axis of the rotating seat 18 and also rotates, so that the connecting seat 22 fixedly connected to the flip shaft 20 rotates around the axis of the rotating seat 18 and also rotates, and then the connecting frame 23 fixedly connected to the connecting seat 22 rotates around the axis of the rotating seat 18 and also rotates, driving the longitudinal rod 24 arranged in the connecting frame 23 to rotate around the axis of the rotating seat 18 and also rotate, so that the vibration block 28 slidably connected to the longitudinal rod 24 drives the separation cover 29 to rotate around the axis of the rotating seat 18 and also rotates, when the rotating gear 21 is disengaged from the arc-shaped toothed plate 27, the ultrafiltration membrane 30 to be cleaned also rotates 180° at this time, until the infrared sensor 37 detects that the ultrafiltration membrane 30 flipped 180° rotates to the bottom of the nozzle 36; It should be noted that, by providing the turning portion, the ultrafiltration membrane 30 to be cleaned can be rotated 180° during the process of being transferred to the bottom of the nozzle 36, so that the subsequent cleaning mechanism can remove the macromolecular impurities on the ultrafiltration membrane 30.

[0043] Reference Figures 1 to 10 , a cleaning mechanism is disposed on the separation tank 1, and the cleaning mechanism is electrically connected to the control device 2; The cleaning mechanism comprises: There are two main pipes 32, and the two main pipes 32 are respectively connected to the inside of the first separation chamber 4 and the inside of the second separation chamber 5; A second valve body 33 is disposed on the main pipeline 32 and is electrically connected to the control device 2. The second valve body 33 is used to control the opening and closing of the main pipeline 32; A branch pipe 34 is disposed on the main pipe 32 and communicated with the main pipe 32; The liquid spraying parts have three groups, and one group of the liquid spraying parts is arranged on the main pipe 32, and the other two groups are symmetrically arranged on the branch pipe 34; The liquid spraying part comprises: The liquid spraying pipe 35, which is arranged in the liquid spraying part on the branch pipe 34 and communicates with the branch pipe 34, and the liquid spraying pipe 35 which is arranged in the liquid spraying part on the main pipe 32 and communicates with the main pipe 32; The nozzle 36 is disposed on the liquid spraying pipe 35 and is connected to the liquid spraying pipe 35 . The nozzle 36 is used to spray cleaning liquid downward to clean the ultrafiltration membrane 30 and the nanofiltration membrane 31 .

[0044] Infrared sensors 37 are provided in the first separation chamber 4 and the second separation chamber 5 . The infrared sensors 37 are electrically connected to the control device 2 . The infrared sensors 37 are used to locate whether the separation cover 29 is rotated to be directly below the spray head 36 .

[0045] The separation tank 1 is provided with two sets of drainage parts, and the drainage parts include: The drain pipe 38 is arranged on the separation tank 1, and the drain pipes 38 in the two sets of drain parts are respectively connected with the inside of the first separation chamber 4 and the inside of the second separation chamber 5; The third valve body 39 is disposed on the drain pipe 38 and is electrically connected to the control device 2 . The third valve body 39 is used to control the opening and closing of the drain pipe 38 .

[0046] Reference Figures 1 to 10 When the ultrafiltration membrane 30 flipped 180° rotates to the bottom of the nozzle 36, the control device 2 controls the second valve body 33 to open so that the cleaning liquid enters the main pipeline 32, and the cleaning liquid in the main pipeline 32 enters the branch pipeline 34, and finally enters the nozzle 36 through the liquid spraying pipe 35. The nozzle 36 sprays the cleaning liquid on the ultrafiltration membrane 30 below, so as to wash away the macromolecular impurities removed from the ultrafiltration membrane 30, thereby completing the cleaning of the ultrafiltration membrane 30; It should be noted that the device is provided with a cleaning mechanism, so that the device can clean the ultrafiltration membrane 30, thereby eliminating the need for staff to manually clean the ultrafiltration membrane 30, thereby improving the purification efficiency of the device for polypeptides to a certain extent.

[0047] Working principle: Refer to Figures 1 to 10The first valve body 8 is controlled to open by the control device 2, and then the polypeptide solution that has been preliminarily purified is transported through the liquid inlet pipe 6. The polypeptide solution in the liquid inlet pipe 6 enters the first liquid feeding bucket 7. The polypeptide solution entering the first liquid feeding bucket 7 collides with the spoiler 15 arranged on the first liquid feeding bucket 7, so that the polypeptide solution is scattered on the ultrafiltration membrane 30. The ultrafiltration membrane 30 filters out the macromolecular impurities in the polypeptide solution. The polypeptide solution passing through the ultrafiltration membrane 30 falls on the first liquid receiving bucket 10. The polypeptide solution on the inner surface of the first liquid receiving bucket 10 converges toward the axial direction of the first liquid receiving bucket 10, so that the flow The polypeptide solution flowing into the connecting pipe 9 enters the second liquid feeding bucket 12 and collides with the spoiler 15 in the second liquid feeding bucket 12, so that the polypeptide solution is scattered on the nanofiltration membrane 31. The polypeptide solution passing through the nanofiltration membrane 31 is further concentrated and purified and falls on the second liquid receiving bucket 14. The polypeptide solution on the inner surface of the second liquid receiving bucket 14 converges toward the axis direction of the second liquid receiving bucket 14, and thus flows into the liquid outlet pipe 13. Finally, the concentrated and purified polypeptide solution is transported to the subsequent freeze-drying equipment through the liquid outlet pipe 13, thereby completing the concentration and purification of the polypeptide solution. When the ultrafiltration membrane 30 needs to be replaced and cleaned after being used for a period of time, the replacement and cleaning of the ultrafiltration membrane 30 is achieved through the following process: the first valve body 8 is controlled to be closed by the control device 2, and then the rotating motor 16 close to the first valve body 8 is controlled to start by the control device 2, so that the rotating shaft 17 fixedly connected to the output end of the rotating motor 16 rotates, so that the rotating seat 18 fixedly connected to the rotating shaft 17 rotates, and then the connecting plate 19 arranged on the rotating seat 18 rotates around the axis of the rotating seat 18, thereby driving the flip shaft 20 rotatably connected to the connecting plate 19 to rotate around the axis of the rotating seat 18. Rotate around the axis of the rotating seat 18, so that the connecting seat 22 fixedly connected to the flip shaft 20 rotates around the axis of the rotating seat 18, driving the connecting frame 23 fixedly connected to the connecting seat 22 to rotate around the axis of the rotating seat 18, so that the longitudinal rod 24 arranged in the connecting frame 23 rotates around the axis of the rotating seat 18, driving the vibration block 28 slidably connected to the longitudinal rod 24 to rotate around the axis of the rotating seat 18, so that the separation cover 29 fixedly connected to the vibration block 28 rotates around the axis of the rotating seat 18, so that the ultrafiltration membrane 30 to be cleaned is rotated out; In the process of the ultrafiltration membrane 30 to be cleaned rotating toward the bottom of the nozzle 36, in the process of the rotating gear 21 meshing with the arc-shaped toothed plate 27, the rotating gear 21 is rotated, and then the flip shaft 20 fixedly connected to the rotating gear 21 rotates around the axis of the rotating seat 18 and also rotates, so that the connecting seat 22 fixedly connected to the flip shaft 20 rotates around the axis of the rotating seat 18 and also rotates, and then the connecting frame 23 fixedly connected to the connecting seat 22 rotates around the axis of the rotating seat 18 and also rotates, driving the longitudinal rod 24 arranged in the connecting frame 23 to rotate around the axis of the rotating seat 18 and also rotate, so that the vibration block 28 slidably connected to the longitudinal rod 24 drives the separation cover 29 to rotate around the axis of the rotating seat 18 and also rotates, when the rotating gear 21 is disengaged from the arc-shaped toothed plate 27, the ultrafiltration membrane 30 to be cleaned also rotates 180° at this time, until the infrared sensor 37 detects that the ultrafiltration membrane 30 flipped 180° rotates to the bottom of the nozzle 36; When the ultrafiltration membrane 30 flipped 180° rotates to the position directly below the nozzle 36, the second valve body 33 is opened by the control device 2 to allow the cleaning liquid to enter the main pipe 32, and the cleaning liquid in the main pipe 32 enters the branch pipe 34, and finally enters the nozzle 36 through the liquid spraying pipe 35. The nozzle 36 sprays the cleaning liquid on the ultrafiltration membrane 30 below, so as to wash away the macromolecular impurities removed from the ultrafiltration membrane 30, thereby completing the cleaning of the ultrafiltration membrane 30; When the cleaning liquid sprayed by the nozzle 36 falls on the ultrafiltration membrane 30 below, the cleaning liquid impacts the ultrafiltration membrane 30, so that the vibration block 28 fixedly connected to the separation cover 29 slides on the longitudinal rod 24. The setting of the vibration spring 25 enables the vibration block 28 to slide back and forth on the longitudinal rod 24, so that the separation cover 29 fixedly connected to the vibration block 28 drives the ultrafiltration membrane 30 to vibrate, so as to facilitate the fall of macromolecular impurities from the ultrafiltration membrane 30. When the nanofiltration membrane 31 needs to be cleaned, the control device 2 controls the rotation motor 16 away from the first valve body 8 to start, thereby rotating the rotation shaft 17 fixedly connected to the output end of the rotation motor 16, so that the rotation seat 18 fixedly connected to the rotation shaft 17 rotates, and then the connecting plate 19 arranged on the rotating seat 18 rotates around the axis of the rotating seat 18, thereby driving the flip shaft 20 rotatably connected to the connecting plate 19 to rotate around the axis of the rotating seat 18, so that the connecting seat 22 fixedly connected to the flip shaft 20 rotates around the axis of the rotating seat 18, and drives the connecting frame 23 fixedly connected to the connecting seat 22 to rotate around the axis of the rotating seat 18, so that the longitudinal rod 24 arranged in the connecting frame 23 rotates around the axis of the rotating seat 18, and drives the vibration block 28 slidably connected to the longitudinal rod 24 to rotate around the axis of the rotating seat 18, so that the separation cover 29 fixedly connected to the vibration block 28 rotates around the axis of the rotating seat 18, so that the nanofiltration membrane 31 to be cleaned is rotated out; In the process of the nanofiltration membrane 31 to be cleaned rotating toward the bottom of the nozzle 36, in the process of the rotating gear 21 meshing with the arc-shaped toothed plate 27, the rotating gear 21 rotates, and then the flip shaft 20 fixedly connected to the rotating gear 21 rotates around the axis of the rotating seat 18 and also rotates, so that the connecting seat 22 fixedly connected to the flip shaft 20 rotates around the axis of the rotating seat 18 and also rotates, and then the connecting frame 23 fixedly connected to the connecting seat 22 rotates around the axis of the rotating seat 18 and also rotates, driving the longitudinal rod 24 arranged in the connecting frame 23 to rotate around the axis of the rotating seat 18 and also rotate, so that the vibration block 28 slidably connected to the longitudinal rod 24 drives the separation cover 29 to rotate around the axis of the rotating seat 18. The wire rotates while rotating. When the rotating gear 21 is disengaged from the arc-shaped tooth plate 27, the nanofiltration membrane 31 to be cleaned also rotates 180° until the infrared sensor 37 detects that the nanofiltration membrane 31 flipped 180° rotates to the bottom of the nozzle 36. When the nanofiltration membrane 31 flipped 180° rotates to the bottom of the nozzle 36, the control device 2 controls the second valve body 33 to open so that the cleaning liquid enters the main pipeline 32. The cleaning liquid in the main pipeline 32 enters the branch pipeline 34 and finally enters the nozzle 36 through the liquid spraying pipe 35. The nozzle 36 sprays the cleaning liquid on the nanofiltration membrane 31 below, thereby washing away the macromolecular impurities removed from the nanofiltration membrane 31 from the nanofiltration membrane 31, thereby completing the cleaning of the nanofiltration membrane 31.

[0048] The above description of the embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A polypeptide purification device for food production, comprising a separation tank (1) and a control device (2), characterized in that: A partition (3) is fixedly arranged inside the separation tank (1), and the partition (3) divides the interior of the separation tank (1) into a first separation chamber (4) and a second separation chamber (5). A liquid inlet pipe (6) communicating with the interior of the first separation chamber (4) is fixedly arranged on the separation tank (1), and a first liquid feeding hopper (7) is fixedly arranged at one end of the liquid inlet pipe (6) located in the first separation chamber (4). A first valve body (8) for controlling the opening and closing of the liquid inlet pipe (6) is arranged on the liquid inlet pipe (6), and the first valve body (8) is electrically connected to the control device (2). A connecting pipe (9) is fixedly arranged on the partition (3), and a first liquid receiving hopper (7) is fixedly arranged at one end of the connecting pipe (9) located in the first separation chamber (4). 10), the axis of the first liquid receiving hopper (10) coincides with the axis of the first liquid delivery hopper (7), the outer portion of the connecting pipe (9) is provided with a sealing sleeve (11) for preventing the liquid in the first separation chamber (4) from entering the second separation chamber (5), the connecting pipe (9) is fixedly provided with a second liquid delivery hopper (12) at one end thereof located in the second separation chamber (5), the separation tank (1) is fixedly provided with a liquid outlet pipe (13) communicating with the interior of the second separation chamber (5), the liquid outlet pipe (13) is fixedly provided with a second liquid receiving hopper (14) at one end thereof located in the second separation chamber (5), the axis of the second liquid receiving hopper (14) coincides with the axis of the second liquid delivery hopper (12), and the polypeptide purification device for food production further comprises: Two groups of spoilers (15) are provided, and the two groups of spoilers (15) are respectively arranged on the inner surface of the first liquid feeding hopper (7) and the inner surface of the second liquid feeding hopper (12), and the spoilers (15) are evenly spaced on the inner surface of the first liquid feeding hopper (7) and the inner surface of the second liquid feeding hopper (12); A driving unit, comprising two groups, and the two groups of driving units are symmetrically arranged on the separation tank (1), and the driving unit is electrically connected to the control device (2); The turning part is arranged on the driving part, and the driving part is provided with four groups of turning parts, and the four groups of turning parts are evenly distributed on the driving part; The auxiliary parts have two groups, and the two groups of auxiliary parts are respectively arranged in the first separation chamber (4) and the second separation chamber (5); A separation portion, disposed on the flip portion; A cleaning mechanism is arranged on the separation tank (1), and the cleaning mechanism is electrically connected to the control device (2).

2. A polypeptide purification device for food production according to claim 1, characterized in that: The driving unit comprises: A rotating motor (16) is fixedly mounted on the separation tank (1) and is electrically connected to the control device (2); A rotating shaft (17) is rotatably disposed on the separation tank (1), and one end of the rotating shaft (17) close to the rotating motor (16) is fixedly connected to an output end of the rotating motor (16); A rotating seat (18) is fixedly arranged at an end of the rotating shaft (17) away from the rotating motor (16); The connecting plate (19) is fixedly arranged on the rotating seat (18), and four evenly distributed connecting plates (19) are arranged on the rotating seat (18).

3. A polypeptide purification device for food production according to claim 2, characterized in that: The turning part comprises: A turning shaft (20) rotatably disposed on the connecting plate (19); A rotating gear (21) fixedly disposed on the flip shaft (20); A connecting seat (22) fixedly disposed on an end of the flip shaft (20) away from the connecting plate (19); A connecting frame (23) fixedly disposed on the connecting seat (22); A longitudinal rod (24) fixedly disposed in the connecting frame (23); A vibration spring (25) is sleeved on the longitudinal rod (24), and two vibration springs (25) are sleeved on the longitudinal rod (24), and ends of the two vibration springs (25) that are away from each other are fixedly connected to the connection frame (23).

4. A polypeptide purification device for food production according to claim 3, characterized in that: The auxiliary part includes: A vertical block (26), the vertical block (26) located in the first separation chamber (4) is fixedly connected to the partition plate (3), and two symmetrically arranged vertical blocks (26) are provided in the first separation chamber (4); the vertical block (26) located in the second separation chamber (5) is fixedly connected to the separation tank (1), and two symmetrically arranged vertical blocks (26) are provided in the second separation chamber (5); The arc-shaped tooth plate (27) is fixedly arranged on the upright block (26), and the circumference of the arc-shaped tooth plate (27) is equal to half the circumference of the rotating gear (21). The arc-shaped tooth plate (27) is used to mesh with the adjacent rotating gear (21) to drive the flip shaft (20) to rotate half a circle.

5. A polypeptide purification device for food production according to claim 4, characterized in that: The separation unit comprises: A vibration block (28) is slidably disposed on the longitudinal rod (24), and the vibration block (28) is fixedly connected to an adjacent vibration spring (25), wherein the vibration spring (25) is in a compressed state; A separation cover (29) is fixedly mounted on the vibration block (28), and the height of the separation cover (29) is equal to the distance between the first liquid feeding hopper (7) and the first liquid receiving hopper (10), and the distance between the first liquid feeding hopper (7) and the first liquid receiving hopper (10) is equal to the distance between the second liquid feeding hopper (12) and the second liquid receiving hopper (14).

6. A polypeptide purification device for food production according to claim 5, characterized in that: An ultrafiltration membrane (30) for removing macromolecular impurities is fixedly disposed on the separation cover (29) in the first separation chamber (4), and a nanofiltration membrane (31) for concentrating the polypeptide solution is fixedly disposed on the separation cover (29) in the second separation chamber (5).

7. A polypeptide purification device for food production according to claim 6, characterized in that: The cleaning mechanism comprises: There are two main pipes (32), and the two main pipes (32) are respectively connected to the interior of the first separation chamber (4) and the interior of the second separation chamber (5); a second valve body (33), which is arranged on the main pipeline (32) and is electrically connected to the control device (2), and the second valve body (33) is used to control the opening and closing of the main pipeline (32); a branch pipeline (34) disposed on the main pipeline (32) and communicating with the main pipeline (32); The liquid spraying parts have three groups, one of which is arranged on the main pipeline (32), and the other two are symmetrically arranged on the branch pipeline (34).

8. A polypeptide purification device for food production according to claim 7, characterized in that: The liquid spraying part comprises: a liquid spraying pipe (35), the liquid spraying pipe (35) arranged in the liquid spraying portion on the branch pipe (34) being in communication with the branch pipe (34), and the liquid spraying pipe (35) arranged in the liquid spraying portion on the main pipe (32) being in communication with the main pipe (32); A spray head (36) is disposed on the liquid spray pipe (35) and is in communication with the liquid spray pipe (35). The spray head (36) is used to spray a cleaning liquid downward to clean the ultrafiltration membrane (30) and the nanofiltration membrane (31).

9. A polypeptide purification device for food production according to claim 8, characterized in that: Infrared sensors (37) are provided in the first separation chamber (4) and the second separation chamber (5). The infrared sensors (37) are electrically connected to the control device (2). The infrared sensors (37) are used to determine whether the separation cover (29) is rotated to directly below the spray head (36).

10. A polypeptide purification device for food production according to claim 9, characterized in that: The separation tank (1) is provided with two sets of liquid discharge parts, and the liquid discharge parts include: a liquid discharge pipe (38) disposed on the separation tank (1), wherein the liquid discharge pipes (38) in the two groups of liquid discharge parts are respectively connected to the interior of the first separation chamber (4) and the interior of the second separation chamber (5); The third valve body (39) is arranged on the liquid discharge pipe (38) and is electrically connected to the control device (2). The third valve body (39) is used to control the opening and closing of the liquid discharge pipe (38).

Citation Information

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