Cooperative layer-by-layer anti-aging component based on Tri-cell active encapsulation

Abstract

The invention relates to the field of cosmetics, and particularly discloses a synergistic layer-by-layer anti-aging component based on Tri-cell active packaging. According to the cosmetic, the anti-aging plant extract and the cell metabolism activator are prepared to form a synergistic layer-by-layer anti-aging component, and after the cosmetic containing the component is used, the anti-aging plant extract and the cell metabolism activator in the cosmetic can permeate the cuticle and directly wrap cells acting on the epidermal layer and the corium layer, so that the anti-aging effect is achieved. The anti-aging plant extract can directly act on aging cells, block the cell aging process and prevent aging cell diffusion, and the cell metabolism activator accelerates irreversible aging cell apoptosis on one hand and promotes accelerated growth of newborn cells from multiple angles on the other hand, so that the aging cells in the skin layer gradually disappear, and the anti-aging effect is achieved. The proportion of newborn cells in the skin layer is increased, the whole skin anti-aging effect is truly achieved from the cellular level, and the anti-aging effect is efficient, safe and stable.

Description

Technical Field

[0001] The invention belongs to the technical field of cosmetics, and in particular relates to a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation. Background Art

[0002] With the aging of the population and the growing demand for health and beauty, anti-aging research has become a hot topic in the fields of cosmetics and medicine. Skin aging is a complex biological process, which is mainly caused by the combined action of endogenous and exogenous factors. Endogenous factors include genes, metabolism, etc., and exogenous factors include ultraviolet rays, pollution, etc. These factors lead to the decline of skin cell function, collagen loss, elastic fiber breakage and weakened antioxidant capacity, which leads to wrinkles, sagging, pigmentation and other aging phenomena.

[0003] At present, anti-aging cosmetics mainly work in the following ways: (1) anti-oxidation and scavenging free radicals; (2) promoting collagen synthesis; (3) inhibiting the activity of matrix metalloproteinases (MMPs); (4) enhancing skin barrier function. However, existing anti-aging products often have problems such as single effect, poor permeability, and insufficient stability. In addition, existing cosmetics can often only delay aging. Overall, it is still difficult to effectively prevent the overall aging process of the skin, unable to achieve true anti-aging, and difficult to meet consumers' demand for efficient, safe, and long-lasting anti-aging.

[0004] In summary, developing an efficient, safe and stable anti-aging composition and cosmetics thereof has important market value and social significance. Summary of the invention

[0005] In order to overcome the deficiencies of the prior art, the purpose of the present invention is to provide a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation to solve the problem that existing cosmetics can only delay the cellular aging process but cannot effectively prevent the overall aging of the skin.

[0006] To achieve the above object, the present invention provides the following technical solutions:

[0007] A synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation, including anti-aging plant extracts and cell metabolism activators.

[0008] Preferably, the anti-aging plant extract comprises Lithospermum officinale stem cell extract.

[0009] Preferably, the method for obtaining the lithospermum officinale stem cell extract is:

[0010] Take the root tissue of Lithospermum officinale and disinfect it for later use;

[0011] forming a wound on the disinfected lithospermum root tissue, thereby inducing the production of callus tissue on the lithospermum root tissue;

[0012] A stable cell population was isolated from callus tissue as R. chinensis stem cells;

[0013] Cultivating and propagating comfrey stem cells on a culture medium;

[0014] Transferring the lithospermum stem cells that have been propagated for several generations into a liquid medium suspension and continuing to culture them to obtain a large number of lithospermum stem cells;

[0015] Take lithospermum stem cells and homogenize them under high pressure to extract the oil-soluble and water-soluble components in the lithospermum stem cell homogenate, stabilize them in the liposome bilayer to form liposomes, and use them as lithospermum stem cell extract.

[0016] Preferably, the cell metabolism promoter includes NMN and fibronectin.

[0017] A preparation method of a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation is applied to a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation, comprising the following steps:

[0018] preparing comfrey stem cell extract into an anti-aging plant extract;

[0019] NMN and fibronectin are mixed to prepare a cell metabolism promoter;

[0020] Premixing the anti-aging plant extract and the cell metabolism promoter to form a premix;

[0021] The premix is ​​placed in a microfluidizer and homogenized at a pressure of 100-120 MPa to obtain an anti-aging composition.

[0022] A use of a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation in the preparation of skin care products or cosmetics, and an application in skin care products or cosmetics.

[0023] Preferably, the skin care product or cosmetic is an aqueous solution, emulsion, cream, essence, facial mask or gel.

[0024] An anti-aging cosmetic comprises a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation.

[0025] Compared with the prior art, the present invention has the following beneficial effects:

[0026] The present invention configures anti-aging plant extracts and cell metabolism promoters to form a synergistic layer-by-layer anti-aging component. After using cosmetics containing the component, the user's skin can quickly absorb the composition in the cosmetics, and the composition helps multiple ingredients in the cosmetics to play a greater role. The anti-aging plant extracts and cell metabolism promoters in the cosmetics can penetrate the stratum corneum and directly wrap the cells acting on the epidermis and dermis, and enhance the absorption of active ingredients by deconstructing different skin layers. The anti-aging plant extracts can directly act on senescent cells, block the cell aging process, and prevent the spread of senescent cells. The cell metabolism promoter accelerates the irreversible apoptosis of senescent cells on the one hand, and promotes the accelerated growth of new cells from multiple angles on the other hand, thereby causing the senescent cells in the skin layer to gradually disappear, and increasing the proportion of new cells in the skin layer, thereby achieving true overall skin anti-aging at the cellular level, and the anti-aging effect is efficient, safe, and stable.

[0027] The synergistic layer-by-layer anti-aging components integrate orientation, stimulation, penetration, empowerment and revitalization, helping the active ingredients and multiple anti-aging ingredients in cosmetics to directly reach different skin layers to act, fundamentally achieving skin rejuvenation and anti-aging. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 A block diagram of a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation disclosed in the present invention;

[0029] Figure 2 A flowchart of the method for obtaining the lithospermum officinale stem cell extract disclosed in the present invention;

[0030] Figure 3 This is a flowchart of a method for preparing a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation disclosed in the present invention. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] Example:

[0033] See also Figure 1 - Figure 3 As shown, a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation, including anti-aging plant extracts and cell metabolism activators.

[0034] From the above, it can be seen that by configuring anti-aging plant extracts and cell metabolism promoters to form a synergistic layer-by-layer anti-aging component, after using cosmetics containing this component, the anti-aging plant extracts and cell metabolism promoters in the cosmetics can penetrate the stratum corneum, directly wrap and act on the cells of the epidermis and dermis, and the anti-aging plant extracts can directly act on senescent cells, block the cell aging process, and prevent the spread of senescent cells. On the one hand, the cell metabolism promoter accelerates the irreversible apoptosis of senescent cells, and on the other hand, promotes the accelerated growth of new cells from multiple angles, thereby making the senescent cells in the skin layer gradually disappear and increasing the proportion of new cells in the skin layer, thereby achieving true overall skin anti-aging at the cellular level, and the anti-aging effect is efficient, safe and stable.

[0035] The anti-aging plant extract includes comfrey stem cell extract.

[0036] Lithospermum is a perennial herb that has long been used as a medicine for treating wounds, eczema, inflammation, ulcers and many other problems. Lithospermum extract has the ability to stimulate cell proliferation, accelerate wound healing, and promote tissue formation. Lithospermum is rich in mucopolysaccharides and has extraordinary water storage efficiency. It also has anti-inflammatory, analgesic and vasoconstrictor effects. Extracting lithospermum stem cell extract as an active ingredient can enhance the vitality of skin stem cells, significantly restore the proliferation ability of epidermal stem cells, promote young skin stem cells to differentiate into new skin cells, replace aging and damaged skin cells, form an effective skin barrier, maintain skin smoothness, and protect skin stem cells against negative environmental influences.

[0037] The method for obtaining the lithospermum officinale stem cell extract is as follows:

[0038] Take the root tissue of Lithospermum officinale and disinfect it for later use;

[0039] forming a wound on the disinfected lithospermum root tissue, thereby inducing the production of callus tissue on the lithospermum root tissue;

[0040] A stable cell population was isolated from callus tissue as R. chinensis stem cells;

[0041] Cultivating and propagating comfrey stem cells on a culture medium;

[0042] Transferring the lithospermum stem cells that have been propagated for several generations into a liquid medium suspension and continuing to culture them to obtain a large number of lithospermum stem cells;

[0043] Take lithospermum stem cells and homogenize them under high pressure to extract the oil-soluble and water-soluble components in the lithospermum stem cell homogenate, stabilize them in the liposome bilayer to form liposomes, and use them as lithospermum stem cell extract.

[0044] The cell metabolism promoters include NMN and fibronectin.

[0045] NMN is an EX cell communication factor that can enable aging cells to metabolize in time and revitalize new cells. It can work with NAD+ on cells to induce apoptosis of aging cells, accelerate cell regeneration and replication, stimulate collagen production, and realize the cell life cycle. Fibronectin can maintain the integrity of skin tissue by mediating adhesion between cells and cells, and between cells and matrix, highly coordinate skin tissue behavior, maintain healthy skin metabolism, promote dermal tissue regeneration, enhance skin barrier function, maintain healthy skin structure, and relieve skin inflammation.

[0046] A method for preparing a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation comprises the following steps:

[0047] preparing comfrey stem cell extract into an anti-aging plant extract;

[0048] NMN and fibronectin are mixed to prepare a cell metabolism promoter;

[0049] Premixing the anti-aging plant extract and the cell metabolism promoter to form a premix;

[0050] The premix is ​​placed in a microfluidizer and homogenized at a pressure of 100-120 MPa to obtain an anti-aging composition.

[0051] When using this anti-aging composition, the anti-aging plant extracts and cell metabolism promoters can penetrate the stratum corneum into the epidermis and dermis to wrap around the cells and act on them. The comfrey stem cell extract acts on senescent cells to block the spread of senescent cells. NMN and intercellular NAD+ work together to induce apoptosis of senescent cells, accelerate cell regeneration and replication, stimulate collagen production, and then realize the cell life cycle, so that the senescent cells in the skin gradually disappear, and the proportion of new cells in skin cells is increased, achieving true skin cell renewal, thereby meeting the anti-aging needs of users.

[0052] A use of a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation in the preparation of skin care products or cosmetics.

[0053] The skin care products or cosmetics are aqueous solutions, emulsions, creams, essences, facial masks or gels.

[0054] An anti-aging cosmetic comprises a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation.

[0055] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, unless they are contradictory.

[0056] In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other.

Claims

1. A synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation, characterized in that: Includes anti-aging plant extracts and cell metabolism activators.

2. A synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation according to claim 1, characterized in that: The anti-aging plant extract includes comfrey stem cell extract.

3. A synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation according to claim 2, characterized in that: The method for obtaining the lithospermum officinale stem cell extract is as follows: Take the root tissue of Lithospermum officinale and disinfect it for later use; forming a wound on the disinfected lithospermum root tissue, thereby inducing the production of callus tissue on the lithospermum root tissue; A stable cell population was isolated from callus tissue as R. chinensis stem cells; Cultivating and propagating comfrey stem cells on a culture medium; Transferring the lithospermum stem cells that have been propagated for several generations into a liquid medium suspension and continuing to culture them to obtain a large number of lithospermum stem cells; Take lithospermum stem cells and homogenize them under high pressure to extract the oil-soluble and water-soluble components in the lithospermum stem cell homogenate, stabilize them in the liposome bilayer to form liposomes, and use them as lithospermum stem cell extract.

4. The synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation according to claim 1, characterized in that: The cell metabolism promoters include NMN and fibronectin.

5. A method for preparing a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation, characterized in that: A synergistic layer-by-layer anti-aging component based on Tri-cel active encapsulation as described in any one of claims 1 to 4, comprising the following steps: preparing comfrey stem cell extract into an anti-aging plant extract; NMN and fibronectin are mixed to prepare a cell metabolism promoter; Premixing the anti-aging plant extract and the cell metabolism promoter to form a premix; The premix is ​​placed in a microfluidizer and homogenized at a pressure of 100-120 MPa to obtain an anti-aging composition.

6. An application of a synergistic layer-by-layer anti-aging component based on Tri-cel active encapsulation in the preparation of skin care products or cosmetics, characterized in that: Application in skin care products or cosmetics.

7. The use of a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation in the preparation of skin care products or cosmetics according to claim 6, characterized in that: The skin care products or cosmetics are aqueous solutions, emulsions, creams, essences, facial masks or gels.

8. An anti-aging cosmetic, characterized in that: It comprises a synergistic layer-by-layer anti-aging component based on Tri-cell active encapsulation as described in any one of claims 1 to 4.

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