External ointment for treating burns and scalds and skin injury infection and preparation method thereof

Abstract

The invention relates to an external ointment for wound treatment, which is mainly used for treating burns and scalds and also used for treating skin soft tissue injury caused by other reasons such as acid-base corrosion, skin soft tissue injury and the like. The traditional Chinese medicine belongs to a wet bandaging therapy, and has the advantages of good effect, stable medicine property, no toxic or side effect, simplicity, feasibility, low price, no injury surface exposure, mobility of a patient during treatment, no obvious scar formation without skin grafting, easy acceptance by the patient and the like if the medicine needs to be carefully changed. Intravenous injection or intramuscular injection or oral administration of a critical patient such as replenishment liquid acid-base balance anti-infection and the like needs to be carried out simultaneously, so that the aim of curing can be achieved.

Description

Background Art

[0002] Some patients with burns, scalds, trauma or infections, and patients with small-area mild symptoms, can be cured with a little badger oil, erythromycin ointment or MEBO moisturizing ointment. However, for patients with larger areas or infected and suppurated, the effect is often unsatisfactory. Although antibiotics can be dripped intravenously and electrolytes and other fluids can be supplemented, more serious injuries are still difficult to heal or leave scars. Therefore, an external ointment for treating burns, scalds and skin injury infections has been developed. Summary of the invention

[0003] Prescription composition:

[0004] One part of hair, two parts of honeysuckle, two parts of Rhizoma Coptidis, two parts of Salvia miltiorrhiza, two parts of Polygonum cuspidatum, two parts of propolis, 6.5 parts of beeswax, and 40 parts of sesame oil.

[0005] Preparation method of burn quick healing spirit:

[0006] 1. Equipment used: an iron pot, an iron colander, an iron spoon, several stainless steel pots or enamel pots, several small glass bottles for packaging (the glass bottles need to be heated without exploding), all of which should be washed and dried for later use, and two pieces of medical gauze.

[0007] 3. Preparation method: First pour sesame oil into an iron pot without covering it, so that you can observe the cooking process and stir it at any time. Heat the bottom of the pot with firewood over high heat, then put hair in. Wait until the hair turns into charcoal, then add honeysuckle, coptis chinensis, salvia miltiorrhiza, knotweed and propolis. Continue to boil over high heat until it turns black and charcoal-like. When the propolis is completely melted, remove all the residue with a colander, and press with an iron spoon until no liquid leaks out. Keep the residue far away, especially in summer to prevent spontaneous combustion.

[0008] After the beeswax is completely dissolved, collect the paste, filter it through two layers of gauze into a stainless steel or enamel tank, cool it down slightly, divide it into small glass bottles and seal them for later use. (Divided into two sizes of glass bottles, 250g and 70g)

[0009] An unopened bottle of medicine can be kept for more than five years (it is best to store it in a cool and dry place). After opening, it should be used up within half a month and not more than one month.

[0010] Pharmacological action:

[0011] This group of drugs has the effects of clearing away heat and detoxifying, antibacterial and anti-inflammatory, promoting blood circulation, stopping bleeding and relieving pain, improving microcirculation, and promoting microcirculation regeneration in the lesion area, thereby improving the blood supply in the lesion area, promoting the removal of dead tissue and the regeneration of muscle, achieving the effects of muscle growth and skin growth, and tissue regeneration, thereby promoting the healing of the wound surface. At the same time, it also has the effect of relieving pain. Sesame oil, propolis, and beeswax provide nutrition to the wound surface and protect the wound surface. In addition, honeysuckle and Sichuan coptis have a strong bactericidal effect. Salvia miltiorrhiza and Polygonum cuspidatum can promote blood circulation, promote blood circulation and remove blood stasis, thereby preventing the aggravation of infection and promoting the recovery of the wound surface. The moist wound surface is conducive to the tissue absorbing nutrients and growing faster. It has a strong effect of removing dead tissue, regenerating muscle and skin, and a good effect of softening and dissolving scabs. Therefore, scab removal and scar prevention can be achieved without scab cutting, so that the wound surface can be well recovered without obvious scar formation.

[0012] Directions:

[0013] Once a patient has a burn, scald, skin defect or infection, the wound surface and the whole body should be checked immediately. In severe cases, supportive therapy should be given as soon as possible, fluid should be supplemented to maintain electrolyte balance, and anti-infection and other symptomatic treatments should be given. Blisters on the wound surface should be punctured after disinfection to release exudate, and the peeled epidermis and necrotic dermis and subcutaneous tissue should be cut off. However, the dermis and the soft tissue below are not required to be cut clean at one time, but the tissue that may survive should be preserved as much as possible. To ensure as many skin islands as possible to promote tissue regeneration and recovery. However, the necrotic scabs and tissues must be thoroughly cleaned. Generally, there is more secretion on a larger wound surface, and the dressing should be changed once or twice a day depending on the situation. Some even need to be changed three times, and each time the necrotic tissue and the pseudomembrane formed need to be removed. After the secretion decreases, it can be changed every day or every other day. However, the wound surface must be cleaned every time, and colored potions are prohibited on the wound surface. To avoid leaving pigment spots after healing. In the future, the dressing can be changed every three or four days. After basic healing, change the dressing two to five times depending on the situation until healing and prevent or reduce scar formation.

[0014] It should be noted that the ointment should be evenly applied on the dressing each time. The ointment should be applied thickly at the beginning and then thinned according to the condition of the patient, but no dead corners or gaps should be left. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a photo of the drug packaging. Figure 2 These are comparison photos of patients before and after treatment with this drug.

[0017] advantage:

[0018] 1. Easy to use, no special equipment or conditions are required, only sterile dressings and this ointment are needed.

[0019] 2. The cost is low, much lower than the cost of Western medicine treatment.

[0020] 3. The pain is small and the patients can easily accept it. Generally, most patients do not need to take painkillers. After using it, the patients feel better, the stress is reduced, and it is conducive to healing.

[0021] 4. It can prevent reinfection. Since it is a bandaging therapy, the patient can move more freely, which is conducive to recovery and prevention of joint stiffness.

[0022] 5. If used correctly, used early, and used several times after healing, skin grafting is generally not required and scars will not form.

[0023] 6. The medicine does not need special storage, so it can be used as a household emergency medicine for timely use after burns (scalds) and external wounds.

[0024] 7. This ointment is superior to other commonly used external ointments, liquid medicines and powders for treating burns.

[0025] 8. Some patients may have allergic reactions due to physical constitution and other reasons, such as rash and itching. Immediately use anti-allergic drugs for internal or external use. Those with severe symptoms should seek medical attention in time.

[0026] Typical medical history:

[0027] Case 1: Yang XX, female, 20 years old, an employee of a company, was carrying a basin of sulfuric acid to clean equipment, but she accidentally fell down, and her head, face, neck, chest, back, upper limbs and front thighs were corroded by sulfuric acid, with a depth of more than II° and an area of ​​more than 37%. The chest and upper limbs were III° and reached 10%. I immediately washed the wound with saline after receiving the patient. There were no blisters, all of which were eschars of varying degrees. The pain was severe. No eschar was removed. First, "Burn Quick Healing" ointment was applied externally. On the second day, part of the eschar softened and was removed. After that, the ointment dressing was changed once a day, and the remaining eschar was gradually removed and carefully retained. The skin island can survive until the necrotic tissue is completely removed. Part of the wound has reached the muscle layer. The ointment dressing is changed every two days. After ten days, new granulation tissue has been seen. After eighteen days, the ointment dressing is changed to be changed every three days and slightly pressure bandaged. After 40 days, new skin has grown on some wounds. Continue to apply the ointment dressing of the present invention until about 60 days, and the wounds are completely healed. It is required that the wound part should be protected from light, and continue to apply the ointment, and the wound is healed on the 68th day.

[0028] After treatment, in addition to applying this ointment dressing, the patient was given fluid replacement for the first sixty days to maintain acid-base electrolyte balance and to receive intravenous antibiotics and necessary hormone treatment (photos before and after treatment are attached).

[0029] Case 2: Liu XX, 12 years old, male, accidentally spilled porridge on his chest, abdomen, forearms and legs when he was cooking porridge. After removing his clothes, it was found that his forearms, chest, back, abdomen and front of both thighs were all burned. There were dense blisters of varying sizes, some of which had ruptured and tissue fluid was oozing out. The skin on the edge was red. The diagnosis was that the edge was shallow II°, accounting for about 7%, and the rest was deep II°, accounting for about 39%. In addition to immediate fluid replenishment and anti-infection. After the wound was rinsed with physiological saline, the necrotic skin on the surface of the blister was cut off, the exuded tissue fluid was removed, and the ointment dressing was applied. At the beginning, due to the large amount of exudation, the dressing was changed twice a day. On the fourth day, the exudation decreased, and the dressing was changed once a day. Each time the dressing was changed, a thin film of solidified exudate could be seen on the wound. After gently peeling it off, bright red new granulation tissue could be seen underneath. A small amount of necrotic tissue was excised, and then the ointment dressing was applied. After 15 days, all the granulation tissue was bright red, and the ointment dressing was changed every two days. On the 21st day, the wound was basically healed, and the fluid input was stopped. The ointment dressing was continued to be changed until the 28th day. The wound was completely healed without scar formation or functional impairment.

[0030] Case 3: Patient XX fell into a valley while fetching water. He suffered an open comminuted fracture of the distal tibia and fibula above the right ankle joint, with bone leakage. The wound and lower limbs were crawling with 2-3 cm long maggots, and the wound emitted a foul odor.

[0031] First, the wound and right lower limb were rinsed with physiological saline to completely remove the maggots. The wound was covered with the ointment dressing of the present invention, and antibiotics and anti-tetanus treatment were dripped. On the second day, the maggots that were not completely removed from the wound surface were still removed, the necrotic skin and soft tissue at the edge of the wound were cut off, and the free necrotic bone tissue was bitten off. The ointment dressing was exchanged once a day, and the necrotic soft tissue and bone tissue were cleaned at the same time. According to the condition, in order to protect life and prevent sepsis, amputation should be performed, which will bring great difficulties to life and even defecation. Therefore, I think that the foot should be kept as much as possible under the premise of ensuring the safety of the patient's life, because the dorsalis pedis artery still has pulsation. After cleaning the wound again, the fracture end was roughly reset, and the necrotic soft tissue and bone tissue were continued to be cleaned. The ointment dressing was exchanged once a day, and the blood circulation of the foot was closely observed. On the twelfth day, new granulation tissue gradually grew from the wound. The ointment dressing was continued to be exchanged to reduce the amount of liquid. By the 40th day, the wound surface was basically flat, and the fracture end was correctly repositioned again. The dressing of the wound continued to be changed every two days. By the 60th day, the wound was healed and fluid input was stopped. The ointment dressing was changed once every three days, and the affected limb was externally fixed with a plaster clamp. On the 80th day, the patient could walk with the help of crutches. On the 90th day, the wound was healed and the basic function of the foot was retained.

Claims

1. A medicine for treating burns and scalds and skin injuries. Burns and scalds include all skin and soft tissue injuries caused by heat, and skin and soft tissue injuries should include knife wounds, abrasions and infected wounds. The ointment of the present invention should include ingredients such as hair, honeysuckle, Sichuan coptis root, salvia miltiorrhiza, knotweed, propolis, yellow wax and sesame oil, and is named "Burns Quick Healing Spirit".

2. As described in 1, the proportion of the ointment of the present invention should be 1 part of hair, 2 parts each of honeysuckle, Sichuan coptis root, salvia miltiorrhiza, knotweed, and propolis, 6.5 parts of yellow wax, and 40 parts of sesame oil.

3. As described in 2, the matrix component of the present invention is sesame oil, and the whole process should be tracked by the pharmacist, from frying sesame, grinding sesame to the whole process of filling oil. Because sesame oil is highly volatile, it does not affect skin respiration, and its formulated medicine is easily soluble in oil, which is superior to other matrices such as rapeseed oil, soybean oil, vaseline lanolin.

4. According to the hair in claim 1, black hair should be selected and washed with alkaline water to remove impurities and oil, then washed with clean water, dried and set aside. Honeysuckle, Sichuan Coptis chinensis, Salvia miltiorrhiza, and Polygonum cuspidatum should also be authentic and high-quality products. After removing impurities, wash them clean, dry and set aside. Propolis and beeswax should be boiled and melted with clean water respectively, and the scum and bottom residue should be skimmed off to make them pure and then weighed for later use.

5. As claimed in claim 4, the present invention uses an iron pot for boiling, and uses iron spoons and iron colanders as utensils, because iron utensils are relatively stable and are not easily chemically changed by heat with the raw materials.

6. This ointment is made by boiling in an iron pot. Because it needs to be constantly stirred and monitored during boiling, it cannot be covered to prevent the oil from overflowing and catching fire. The heating process requires that as much area as possible on the bottom of the pot be heated evenly, so it requires burning with a high fire of wood.

7. After the ointment is successfully boiled, it is required to remove the residue and put it far away to prevent it from catching fire naturally, especially in summer. Then filter the liquid medicine, put it into a glass bottle or other container after it cools down a little, and seal it for later use.

8. The ointment of the present invention should be placed in a cool and dry place. The general shelf life is up to five years. If the surface becomes moldy, it cannot be used.

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