Traditional Chinese medicine composition and traditional Chinese medicine preparation for preventing stroke and pulmonary nodule as well as preparation method and application of traditional Chinese medicine composition and traditional Chinese medicine preparation
Through scientifically compatible traditional Chinese medicine compositions, combined with the "qi-blood-phlegm-colony" co-treatment strategy, the existing drugs focus on a single target and lack of coordinated intervention in the pathological core of "phlegm-stasis joint tumors", and achieved a multi-target effect in preventing stroke and lung nodules.
Patent Information
- Application Number
- CN202510334422.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-20
- Publication Date
- 2025-05-13
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing drugs to prevent stroke or lung nodules mostly focus on a single target, which is prone to drug resistance or side effects. Traditional Chinese medicine compound prescriptions lack synergistic intervention in the pathological core of "phlegm and blood stasis", and the prevention effect is poor.
Through scientific compatibility and combined with the "qi-blood-phlegm-colony" treatment strategy, a traditional Chinese medicine composition is provided, including saffron, Gastrodia elata, tangerine peel, mustard seeds, peach kernels, Cistanche, cinnamon, angelica, cooked Rehmannia, Astragalus, Polygonatum and dried ginger, forming a complementary and mutually beneficial drug combination, regulating Th1/Th2 immune balance, and inhibiting NF-κB inflammation pathway.
This traditional Chinese medicine composition can prevent stroke, reduce blood viscosity, inhibit platelet aggregation, dissipate lung nodules, reduce TNF-α secretion of alveolar macrophages, inhibit fibroblast proliferation, and improve human immunity.
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Figure CN119970981A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of Chinese medicine preparations, and in particular relates to a Chinese medicine composition for preventing stroke and pulmonary nodules, a Chinese medicine preparation, and a preparation method and application thereof. Background Art
[0002] Stroke, also known as cerebral infarction or cerebrovascular accident, is a sudden onset of cerebral blood circulation disorder. It refers to acute cerebral blood circulation disorder caused by various inducing factors in patients with cerebrovascular diseases, which is clinically manifested as symptoms and signs of one-time or permanent brain dysfunction. Stroke is divided into ischemic stroke and hemorrhagic stroke.
[0003] Sarcoidosis is a multi-system and multi-organ granulomatous disease of unknown etiology, which often invades the lungs, bilateral hilar lymph nodes, eyes, skin and other organs. The chest invasion rate is as high as 80% to 90%. The disease is distributed worldwide, with a higher incidence in Europe and the United States, and is rare in oriental ethnic groups. Pulmonary nodules are a common and difficult-to-diagnose disease in thoracic surgery. Its diagnosis and treatment have always been a difficult point in clinical practice and a hot topic of discussion. Its etiology is complex, the clinical manifestations lack specificity, and the diagnosis is difficult, and it is easy to misdiagnose and miss.
[0004] Existing drugs for preventing stroke or lung nodules mostly focus on a single target, such as anticoagulants and anti-inflammatories, and long-term use can easily lead to drug resistance or side effects. Although traditional Chinese medicine compound prescriptions emphasize overall conditioning, they lack synergistic intervention on the core pathological condition of "mutual accumulation of phlegm and blood stasis", and have little effect on preventing stroke or lung nodules. Summary of the invention
[0005] Based on the above technical background, the present invention fills the gap in the prior art by combining scientific compatibility with the "Qi-Blood-Phlegm-Network" co-treatment strategy. The main purpose of the present invention is to provide a Chinese medicine composition, Chinese medicine preparation and its preparation method and application for preventing stroke and pulmonary nodules, so as to overcome the deficiencies in the prior art.
[0006] In order to achieve the above-mentioned invention object, the technical solution adopted by the present invention includes:
[0007] The first aspect of the present invention is to provide a traditional Chinese medicine composition for preventing stroke and pulmonary nodules. The traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 2 to 15 parts by weight of saffron, 8 to 17 parts by weight of gastrodia elata, 8 to 17 parts by weight of tangerine peel, 8 to 17 parts by weight of platycodon grandiflorum, 3 to 12 parts by weight of mustard seeds, 3 to 17 parts by weight of peach kernels, 3 to 17 parts by weight of cistanche deserticola, 2 to 12 parts by weight of cinnamon, 3 to 17 parts by weight of angelica sinensis, 3 to 17 parts by weight of prepared rehmannia, 3 to 17 parts by weight of astragalus, 3 to 17 parts by weight of polygonatum, and 2 to 15 parts by weight of dried ginger.
[0008] Preferably, the traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 3-9 parts by weight of saffron, 10-15 parts by weight of Gastrodia elata, 10-15 parts by weight of Citrus aurantium, 10-15 parts by weight of Platycodon grandiflorum, 5-10 parts by weight of mustard, 5-15 parts by weight of peach kernel, 5-15 parts by weight of Cistanche deserticola, 3-10 parts by weight of cinnamon, 5-15 parts by weight of Angelica sinensis, 5-15 parts by weight of Rehmannia glutinosa, 5-15 parts by weight of Astragalus membranaceus, 5-15 parts by weight of Polygonatum sibiricum, and 3-12 parts by weight of dried ginger.
[0009] More preferably, the traditional Chinese medicine composition for preventing stroke and lung nodules comprises: 3 parts by weight of saffron, 15 parts by weight of Gastrodia elata, 15 parts by weight of Citrus aurantium, 10 parts by weight of Platycodon grandiflorum, 9 parts by weight of mustard, 6 parts by weight of peach kernel, 10 parts by weight of Cistanche deserticola, 6 parts by weight of cinnamon, 10 parts by weight of Angelica sinensis, 10 parts by weight of Rehmannia glutinosa, 10 parts by weight of Astragalus membranaceus, 10 parts by weight of Polygonatum sibiricum, and 6 parts by weight of dried ginger.
[0010] The second aspect of the present invention is to provide a Chinese medicine preparation for preventing stroke and pulmonary nodules, wherein the Chinese medicine preparation is prepared from the Chinese medicine composition for preventing stroke and pulmonary nodules described in the first aspect of the present invention.
[0011] Preferably, the Chinese medicine preparation is an oral liquid or an ointment.
[0012] The third aspect of the present invention is to provide a method for preparing the Chinese medicine preparation according to the second aspect of the present invention, the preparation method comprising the following steps:
[0013] Step 1, adding water to the Chinese medicine composition and boiling it, and combining the filtrate;
[0014] Step 2, concentrating the filtrate under reduced pressure to obtain a concentrated solution;
[0015] Step 3: add auxiliary materials to the concentrated solution, sterilize, and obtain the Chinese medicine preparation.
[0016] In step 1,
[0017] Preferably, water is added to the traditional Chinese medicine composition and boiled for 1 to 5 times, and the amount of water added is 6 to 8 times the mass of the traditional Chinese medicine composition.
[0018] In step 2,
[0019] Preferably, the temperature is raised to 50-70° C., and the reduced pressure is used for concentration until the relative density is 1.10-1.30.
[0020] In step 3,
[0021] Preferably, the auxiliary material is honey or syrup;
[0022] Preferably, the mass ratio of the concentrate to the auxiliary material is (1-3):1.
[0023] The fourth aspect of the present invention is to provide a use of the Chinese medicine composition for preventing stroke and pulmonary nodules according to the first aspect of the present invention in the preparation of a medicine for preventing stroke and pulmonary nodules.
[0024] The beneficial effects of the present invention are:
[0025] (1) The Chinese medicine composition for preventing stroke and pulmonary nodules of the present invention comprises: saffron, gastrodia, tangerine peel, platycodon, mustard, peach kernel, Cistanche, cinnamon, angelica, prepared rehmannia, astragalus, polygonatum and dried ginger. Among them, saffron or safflower is the main drug, gastrodia, tangerine peel and platycodon are the auxiliary drugs, mustard, peach kernel, Cistanche, cinnamon, angelica, prepared rehmannia, astragalus, polygonatum and dried ginger are the adjuvant drugs.
[0026] (2) In the Chinese medicine composition, saffron can promote blood circulation, dissipate stasis, relieve depression and unblock knots, Gastrodia elata can dispel wind and unblock the meridians, Cistanche deserticola has the effect of nourishing the kidney and benefiting essence, Rehmannia glutinosa can nourish blood and nourish yin, benefit essence and fill marrow, Angelica sinensis can nourish blood and promote blood circulation, Cinnamon bark has the effect of nourishing fire and yang, warming the meridians and unblocking the meridians, Dry ginger has the effect of restoring yang and unblocking the meridians, warming the lungs and removing phlegm, Citrus aurantium can regulate qi and relieve fullness, dry dampness and resolve phlegm, Peach kernel can promote blood circulation and dissipate stasis, moisten the intestines and relieve constipation, relieve cough and relieve asthma, Platycodon grandiflorum has the effect of promoting lung and relieving throat, removing phlegm and expelling pus, Mustard can warm the lungs and resolve phlegm, promote qi and dissipate knots and unblock the meridians, Polygonatum sibiricum has the effect of nourishing qi and nourishing yin, strengthening the spleen and moistening the lungs, and Astragalus can nourish qi and raise yang, relieve stagnation and relieve numbness. The various medicinal materials in the Chinese medicine composition complement each other and can play the role of invigorating qi and promoting blood circulation, unblocking the meridians, promoting blood circulation and removing stasis, warming the meridians and unblocking the meridians, moistening the lungs and relieving cough, and resolving phlegm and dissipating knots. It is suitable for people with stroke and lung nodules to take.
[0027] (3) The Chinese medicine composition of the present invention can inhibit the NF-κB inflammatory pathway by regulating the Th1 / Th2 immune balance. The Chinese medicine composition and the Chinese medicine preparation prepared from the Chinese medicine composition can prevent stroke, reduce blood viscosity (whole blood viscosity decreases by ≥15%), and inhibit platelet aggregation (ADP-induced inhibition rate ≥30%); the Chinese medicine composition and the Chinese medicine preparation can also dissipate lung nodules, reduce TNF-α secretion of alveolar macrophages (downregulation ≥40%), inhibit fibroblast proliferation, and improve human immunity.
[0028] (4) The Chinese medicine composition of the present invention uses Chinese medicinal materials that are both medicinal and edible, and is both a Chinese medicine and a food. The Chinese medicine composition can be used to prepare medicines for preventing stroke and lung nodules, and is suitable for all kinds of people to take. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] Figure 1 A flow chart showing the method for preparing the Chinese medicine preparation of the present invention is shown. DETAILED DESCRIPTION
[0030] The present invention will be described in detail below, and the characteristics and advantages of the present invention will become clearer and more distinct with the description.
[0031] The first aspect of the present invention is to provide a traditional Chinese medicine composition for preventing stroke and pulmonary nodules. The traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 2 to 15 parts by weight of saffron, 8 to 17 parts by weight of gastrodia elata, 8 to 17 parts by weight of tangerine peel, 8 to 17 parts by weight of platycodon grandiflorum, 3 to 12 parts by weight of mustard seeds, 3 to 17 parts by weight of peach kernels, 3 to 17 parts by weight of cistanche deserticola, 2 to 12 parts by weight of cinnamon, 3 to 17 parts by weight of angelica sinensis, 3 to 17 parts by weight of prepared rehmannia, 3 to 17 parts by weight of astragalus, 3 to 17 parts by weight of polygonatum, and 2 to 15 parts by weight of dried ginger.
[0032] Preferably, the traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 3-9 parts by weight of saffron, 10-15 parts by weight of Gastrodia elata, 10-15 parts by weight of Citrus aurantium, 10-15 parts by weight of Platycodon grandiflorum, 5-10 parts by weight of mustard, 5-15 parts by weight of peach kernel, 5-15 parts by weight of Cistanche deserticola, 3-10 parts by weight of cinnamon, 5-15 parts by weight of Angelica sinensis, 5-15 parts by weight of Rehmannia glutinosa, 5-15 parts by weight of Astragalus membranaceus, 5-15 parts by weight of Polygonatum sibiricum, and 3-12 parts by weight of dried ginger.
[0033] More preferably, the traditional Chinese medicine composition for preventing stroke and lung nodules comprises: 3 parts by weight of saffron, 15 parts by weight of Gastrodia elata, 15 parts by weight of Citrus aurantium, 10 parts by weight of Platycodon grandiflorum, 9 parts by weight of mustard, 6 parts by weight of peach kernel, 10 parts by weight of Cistanche deserticola, 6 parts by weight of cinnamon, 10 parts by weight of Angelica sinensis, 10 parts by weight of Rehmannia glutinosa, 10 parts by weight of Astragalus membranaceus, 10 parts by weight of Polygonatum sibiricum, and 6 parts by weight of dried ginger.
[0034] In the Chinese medicine composition of the present invention: the maximum daily dosage of saffron is 3 grams. This formula is configured based on a daily dosage of 1 to 3 grams, an optimal dosage of 2 to 3 grams, and a maximum dosage of 3 grams.
[0035] The saffron in the traditional Chinese medicine composition for preventing stroke and lung nodules can be replaced by safflower.
[0036] According to a preferred embodiment of the present invention, the traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 15 parts by weight of safflower, 15 parts by weight of gastrodia elata, 15 parts by weight of tangerine peel, 10 parts by weight of platycodon, 9 parts by weight of mustard, 6 parts by weight of peach kernel, 10 parts by weight of cistanche, 6 parts by weight of cinnamon, 10 parts by weight of angelica, 10 parts by weight of rehmannia prepared, 10 parts by weight of astragalus, 10 parts by weight of polygonatum, and 6 parts by weight of dried ginger.
[0037] In the traditional Chinese medicine composition of the present invention, saffron or safflower is the main drug, gastrodia elata, tangerine peel and platycodon are the assistant drugs, mustard seed, peach kernel, cistanche deserticola, cinnamon bark, angelica, rehmannia glutinosa, astragalus, polygonatum and dried ginger are the adjuvant drugs.
[0038] In the Chinese medicine composition of the present invention, saffron or safflower has the effects of promoting blood circulation, removing blood stasis, relieving depression and opening knots, Gastrodia elata can dispel wind and dredge the meridians, Citrus aurantium and Platycodon grandiflorum can resolve phlegm and disperse knots, mustard has the effects of warming the lungs and resolving phlegm, promoting qi and dispersing knots, and dredge the meridians, peach kernel can promote blood circulation and remove blood stasis, Cistanche deserticola and cinnamon can warm yang and dredge meridians, Angelica sinensis and Rehmannia glutinosa have the effects of nourishing yin and blood, Astragalus membranaceus can replenish qi and strengthen the exterior and regulate immunity, and Polygonatum sibiricum and dried ginger have the effects of warming the middle and strengthening the spleen.
[0039] Optionally, the Chinese medicine composition for preventing stroke and pulmonary nodules further comprises: 5-10 parts by weight of Codonopsis pilosula, preferably, the Chinese medicine composition further comprises: 7 parts by weight of Codonopsis pilosula. Dangsheng has the effect of enhancing blood circulation.
[0040] Optionally, the Chinese medicinal composition for preventing stroke and pulmonary nodules further comprises: 5 to 10 parts by weight of almonds and 5 to 10 parts by weight of selfheal.
[0041] Preferably, the Chinese medicine composition for preventing stroke and pulmonary nodules further comprises: 7 parts by weight of almonds and 7 parts by weight of selfheal.
[0042] Almonds and Prunella Vulgaris have enhanced cough-relieving and knot-dispersing effects.
[0043] Optionally, the Chinese medicinal composition for preventing stroke and pulmonary nodules further comprises: 5 to 10 parts by weight of Eucommia ulmoides leaves.
[0044] Preferably, the Chinese medicinal composition for preventing stroke and pulmonary nodules further comprises: 8 parts by weight of Eucommia ulmoides leaves.
[0045] The second aspect of the present invention is to provide a Chinese medicine preparation for preventing stroke and pulmonary nodules, wherein the Chinese medicine preparation is prepared from the Chinese medicine composition for preventing stroke and pulmonary nodules described in the first aspect of the present invention.
[0046] Preferably, the Chinese medicine preparation is an oral liquid or an ointment.
[0047] The third aspect of the present invention is to provide a method for preparing the Chinese medicine preparation according to the second aspect of the present invention, such as Figure 1 As shown, the preparation method comprises the following steps:
[0048] Step 1, adding water to the Chinese medicine composition and boiling it, and combining the filtrate;
[0049] Step 2, concentrating the filtrate under reduced pressure to obtain a concentrated solution;
[0050] Step 3: add auxiliary materials to the concentrated solution, sterilize, and obtain the Chinese medicine preparation.
[0051] The following is a detailed description of the above steps:
[0052] In step 1, water is added to the traditional Chinese medicine composition and boiled for 1 to 5 times, and the amount of water added is 6 to 8 times the mass of the traditional Chinese medicine composition.
[0053] Preferably, water is added to the traditional Chinese medicine composition for decoction three times, the amount of water added for the first time is 8 times the mass of the traditional Chinese medicine composition, the amount of water added for the second time is 6 times the mass of the traditional Chinese medicine composition, and the amount of water added for the third time is 6 times the mass of the traditional Chinese medicine composition, and the filtrate of each decoction is combined.
[0054] In step 2, the temperature is raised to 50-70° C., and the mixture is concentrated under reduced pressure to a relative density of 1.10-1.30.
[0055] Preferably, the temperature is raised to 60° C. and the reduced pressure is used for concentration until the relative density is 1.10 to 1.15.
[0056] Or, preferably, the temperature is raised to 60° C., and the reduced pressure is used for concentration until the relative density is 1.25 to 1.30.
[0057] In step 3, auxiliary materials are added to adjust the taste of the Chinese medicine preparation.
[0058] The auxiliary material is honey or syrup, preferably, the auxiliary material is honey or xylitol.
[0059] The mass ratio of the concentrated solution to the auxiliary material is (1-3):1. Preferably, the mass ratio of the concentrated solution to the auxiliary material is 2:1.
[0060] After adding auxiliary materials, sterilizing by high pressure, and filling, the Chinese medicine oral liquid is obtained.
[0061] Alternatively, after adding auxiliary materials, simmer until it becomes "hanging flag" (viscous), then sterilize it under high pressure, and then fill it to obtain the Chinese medicine ointment.
[0062] The fourth aspect of the present invention is to provide a use of the Chinese medicine composition for preventing stroke and pulmonary nodules according to the first aspect of the present invention in the preparation of a medicine for preventing stroke and pulmonary nodules.
[0063] Example
[0064] The present invention is further described below by specific examples, which are limited to illustrating the present invention but not to limiting the scope of the present invention. The raw materials used in the examples of the present invention were all purchased.
[0065] Example 1
[0066] A traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 3 parts by weight of saffron, 15 parts by weight of gastrodia elata, 15 parts by weight of tangerine peel, 10 parts by weight of platycodon grandiflorum, 9 parts by weight of mustard seeds, 6 parts by weight of peach kernels, 10 parts by weight of cistanche deserticola, 6 parts by weight of cinnamon bark, 10 parts by weight of angelica sinensis, 10 parts by weight of prepared rehmannia, 10 parts by weight of astragalus, 10 parts by weight of polygonatum, and 6 parts by weight of dried ginger.
[0067] Example 2
[0068] A traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 15 parts by weight of safflower, 15 parts by weight of gastrodia elata, 15 parts by weight of tangerine peel, 10 parts by weight of platycodon grandiflorum, 9 parts by weight of mustard seeds, 6 parts by weight of peach kernels, 10 parts by weight of cistanche deserticola, 6 parts by weight of cinnamon bark, 10 parts by weight of angelica sinensis, 10 parts by weight of rehmannia glutinosa, 10 parts by weight of astragalus, 10 parts by weight of polygonatum, and 6 parts by weight of dried ginger.
[0069] Example 3
[0070] A traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 3 parts by weight of saffron, 10 parts by weight of gastrodia elata, 10 parts by weight of tangerine peel, 10 parts by weight of platycodon grandiflorum, 5 parts by weight of mustard seeds, 5 parts by weight of peach kernels, 5 parts by weight of cistanche deserticola, 3 parts by weight of cinnamon bark, 5 parts by weight of angelica sinensis, 5 parts by weight of rehmannia glutinosa, 5 parts by weight of astragalus, 5 parts by weight of polygonatum, and 3 parts by weight of dried ginger.
[0071] Example 4
[0072] A traditional Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 9 parts by weight of saffron, 15 parts by weight of gastrodia elata, 15 parts by weight of tangerine peel, 15 parts by weight of platycodon grandiflorum, 10 parts by weight of mustard seeds, 15 parts by weight of peach kernels, 15 parts by weight of cistanche deserticola, 10 parts by weight of cinnamon bark, 15 parts by weight of angelica sinensis, 15 parts by weight of rehmannia glutinosa, 15 parts by weight of astragalus, 15 parts by weight of polygonatum, and 12 parts by weight of dried ginger.
[0073] Example 5
[0074] An oral liquid for preventing stroke and pulmonary nodules, the preparation method of the oral liquid comprising the following steps:
[0075] Add water to the traditional Chinese medicine composition described in Example 1 and boil it three times, the amount of water added in the first time is 8 times the mass of the traditional Chinese medicine composition, the amount of water added in the second time is 6 times the mass of the traditional Chinese medicine composition, and the amount of water added in the third time is 6 times the mass of the traditional Chinese medicine composition, and combine the filtrate of each decoction.
[0076] The temperature was raised to 60°C, and the filtrate was concentrated under reduced pressure to a relative density of 1.10-1.15 to obtain a concentrated solution.
[0077] Add auxiliary materials such as honey or xylitol to the concentrate to adjust the taste of the Chinese medicine preparation. The mass ratio of the concentrate to the auxiliary materials is 2:1. Then sterilize by high pressure and package into 10mL / tube of Chinese medicine oral liquid.
[0078] Example 6
[0079] An ointment for preventing stroke and pulmonary nodules, the preparation method of the ointment comprising the following steps:
[0080] Add water to the traditional Chinese medicine composition described in Example 1 and boil it three times, the amount of water added in the first time is 8 times the mass of the traditional Chinese medicine composition, the amount of water added in the second time is 6 times the mass of the traditional Chinese medicine composition, and the amount of water added in the third time is 6 times the mass of the traditional Chinese medicine composition, and combine the filtrate of each decoction.
[0081] The temperature was raised to 60°C, and the filtrate was concentrated under reduced pressure to a relative density of 1.25-1.30 to obtain a concentrated solution.
[0082] Add auxiliary materials such as honey or xylitol to the concentrate to adjust the taste of the Chinese medicine preparation. The mass ratio of the concentrate to the auxiliary materials is 2:1. Simmer until it becomes a "hanging flag" (viscous) state, then sterilize it under high pressure, fill it while hot, seal it and refrigerate it after cooling, and obtain the Chinese medicine paste after filling.
[0083] Typical Cases
[0084] Typical Case 1: Resident Wang took the Chinese medicine oral liquid prepared in Example 5, 20 ml per day, for 30 consecutive days. After 30 days, he felt energetic, walked easily, and his dizziness symptoms were alleviated.
[0085] Typical Case 2: Resident Mr. Li took the Chinese medicine oral liquid prepared in Example 5, 20 ml per day, for 30 consecutive days. After 30 days, his asthma was relieved, he no longer coughed at night, he was energetic during the day, and his fatigue was reduced.
[0086] The present invention has been described in detail above in conjunction with specific implementations and exemplary examples, but these descriptions cannot be understood as limiting the present invention. Those skilled in the art understand that, without departing from the spirit and scope of the present invention, a variety of equivalent substitutions, modifications or improvements may be made to the technical solution of the present invention and its implementation methods, all of which fall within the scope of the present invention. The scope of protection of the present invention shall be subject to the attached claims.
Claims
1. A Chinese medicine composition for preventing stroke and pulmonary nodules, characterized in that: The Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 2-15 parts by weight of saffron, 8-17 parts by weight of gastrodia elata, 8-17 parts by weight of tangerine peel, 8-17 parts by weight of platycodon grandiflorum, 3-12 parts by weight of mustard seeds, 3-17 parts by weight of peach kernels, 3-17 parts by weight of cistanche deserticola, 2-12 parts by weight of cinnamon bark, 3-17 parts by weight of angelica sinensis, 3-17 parts by weight of rehmannia glutinosa, 3-17 parts by weight of astragalus, 3-17 parts by weight of polygonatum, and 2-15 parts by weight of dried ginger.
2. The Chinese medicine composition for preventing stroke and pulmonary nodules according to claim 1, characterized in that: The Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 3-9 parts by weight of saffron, 10-15 parts by weight of gastrodia elata, 10-15 parts by weight of tangerine peel, 10-15 parts by weight of platycodon grandiflorum, 5-10 parts by weight of mustard seeds, 5-15 parts by weight of peach kernels, 5-15 parts by weight of cistanche deserticola, 3-10 parts by weight of cinnamon bark, 5-15 parts by weight of angelica sinensis, 5-15 parts by weight of rehmannia glutinosa, 5-15 parts by weight of astragalus, 5-15 parts by weight of polygonatum, and 3-12 parts by weight of dried ginger.
3. The Chinese medicine composition for preventing stroke and pulmonary nodules according to claim 2, characterized in that: The Chinese medicine composition for preventing stroke and pulmonary nodules comprises: 3 parts by weight of saffron, 15 parts by weight of gastrodia elata, 15 parts by weight of tangerine peel, 10 parts by weight of platycodon grandiflorum, 9 parts by weight of mustard seeds, 6 parts by weight of peach kernels, 10 parts by weight of cistanche deserticola, 6 parts by weight of cinnamon bark, 10 parts by weight of angelica sinensis, 10 parts by weight of prepared rehmannia, 10 parts by weight of astragalus, 10 parts by weight of polygonatum, and 6 parts by weight of dried ginger.
4. A Chinese medicine preparation for preventing stroke and pulmonary nodules, characterized in that: The Chinese medicine preparation is prepared from the Chinese medicine composition for preventing stroke and pulmonary nodules according to any one of claims 1 to 3.
5. The Chinese medicine preparation according to claim 4, characterized in that: The Chinese medicine preparation is an oral liquid or an ointment.
6. A method for preparing the Chinese medicine preparation according to claim 4 or 5, characterized in that: The preparation method comprises the following steps: Step 1, adding water to the Chinese medicine composition and boiling it, and combining the filtrate; Step 2, concentrating the filtrate under reduced pressure to obtain a concentrated solution; Step 3: add auxiliary materials to the concentrated solution, sterilize, and obtain the Chinese medicine preparation.
7. The preparation method according to claim 6, characterized in that: In step 1, Add water to the traditional Chinese medicine composition and boil it for 1 to 5 times, wherein the amount of water added is 6 to 8 times the mass of the traditional Chinese medicine composition.
8. The preparation method according to claim 6, characterized in that: In step 2, Raise the temperature to 50-70°C and concentrate under reduced pressure to a relative density of 1.10-1.
30.
9. The preparation method according to claim 6, characterized in that: In step 3, The auxiliary material is honey or syrup; The mass ratio of the concentrated solution to the auxiliary material is (1-3):
1.
10. Use of the traditional Chinese medicine composition for preventing stroke and pulmonary nodules according to any one of claims 1 to 3 in the preparation of medicines for preventing stroke and pulmonary nodules.