Optical fiber balloon catheter

Abstract

The invention discloses an optical fiber balloon catheter, and relates to the technical field of medical instruments. The optical fiber balloon catheter comprises a catheter main body, a balloon and a flow slowing component, the balloon is arranged at the far end of the catheter body, and medicine is arranged on the surface of the balloon. At least in the process of conveying the balloon to a target part, the flow slowing part is located on the receiving side, receiving fluid impact, of the balloon, and the flow slowing part is used for slowing down flushing of fluid to medicine on the surface of the balloon in the process; wherein when the optical fiber balloon catheter performs reverse motion relative to fluid, the welcoming side is the far-end side of the balloon; when the optical fiber balloon catheter moves in the same direction relative to fluid, the receiving side is the near-end side of the balloon. The structure of the optical fiber balloon catheter is improved, scouring of fluid to the balloon in the conveying process is relieved, and loss of the photosensitizer on the surface of the balloon in the conveying process is effectively reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a fiber optic balloon catheter. Background Art

[0002] Among many cardiovascular diseases, vascular stenosis is one of the more serious ones. Vascular interventional therapy is an important treatment method for revascularization of vascular stenosis.

[0003] Intravascular stenosis is usually treated with balloon angioplasty or stent implantation, but both methods have their own shortcomings: after balloon angioplasty, the endothelium of the dilated artery segment is damaged and the elastic fibers are broken, leading to thrombosis and intimal hyperplasia; the balloon has a short expansion time during use and lacks long-term support, resulting in elastic retraction and remodeling of the vessel wall; long-term placement of vascular stents will also act as foreign bodies and produce a proliferative response in the body, leading to restenosis within the vascular stent.

[0004] To address the above issues, a natural vascular stent has emerged. A photosensitizer is coated on the balloon. After the balloon is expanded, the photosensitizer is released to the inner wall of the blood vessel. The optical fiber emits light of a specific wavelength (400-500nm) to activate the photosensitizer, causing the amino acids on the inner wall of the blood vessel to form covalent cross-links, which supports the blood vessel and avoids the problem of vascular retraction.

[0005] In the prior art, for example, the patent with publication number CN119034087A discloses a drug balloon delivery catheter, including a catheter body, the catheter body is provided with a balloon body and a blocking balloon, and the surface of the balloon body is evenly distributed with drugs; the balloon body is in an olive-shaped structure, and after the balloon body reaches the target treatment area, the filling hole provided in the catheter body is filled with filling liquid to the balloon body to expand the balloon body, and the balloon body is fully fitted with the target inner wall after expansion; before the balloon body expands, the blocking balloon is filled to block the blood in the blood vessel. However, the prior art only considers forming a completely blocked area in the target treatment area during a short period of drug release to block the scouring of the balloon body by blood flow, and in the process of delivering the balloon to the lesion tissue, due to the large blood flow rate and flow rate, the photosensitizer on the balloon surface will lose part of itself with the scouring of the blood flow, so that only part of the photosensitizer can reach the lesion location. Summary of the invention

[0006] The main purpose of the present invention is to provide a fiber optic balloon catheter, which aims to slow down the scouring of the fiber optic balloon catheter by fluid during transportation and reduce the loss of drugs on the balloon surface during transportation.

[0007] To achieve the above object, the present invention provides a fiber optic balloon catheter, comprising: a catheter body; a balloon, disposed at the distal end of the catheter body, wherein medicine is disposed on the surface of the balloon; and A slow-flow component, at least in the process of delivering the balloon to the target site, the slow-flow component is located on the side of the balloon that meets the impact of the fluid, and the slow-flow component is used to slow down the scouring of the fluid on the drug on the surface of the balloon during this process; Wherein, when the fiber optic balloon catheter moves in the reverse direction relative to the fluid, the welcoming side is the distal side of the balloon; when the fiber optic balloon catheter moves in the same direction relative to the fluid, the welcoming side is the proximal side of the balloon.

[0008] Optionally, the radial dimension of the catheter body when the flow-slowing component is in the working state is defined as a, and the radial dimension of the catheter body when the balloon is in the folded state is defined as b, and the following relationship is satisfied: b≤a <c; Where c is the inner diameter of human blood vessels.

[0009] Optionally, the flow-slowing component is a fillable body, the catheter body is provided with a first channel and a second channel both for introducing liquid, the balloon is connected to the first channel, and the fillable body is provided at the distal end of the catheter body and connected to the second channel.

[0010] Optionally, the projection of the inflatable body in the radial direction of the catheter body is circular, elliptical, peanut-shaped, "T"-shaped, umbrella-shaped or conical.

[0011] Optionally, the flow-slowing component is a foldable structure, the catheter body is provided with a third channel for the passage of the flow-slowing guidewire, the third channel has an outlet located on the distal side of the balloon, the foldable structure is transported to the outside of the outlet of the third channel through the flow-slowing guidewire and automatically unfolds after detaching from the outlet of the third channel.

[0012] Optionally, the foldable structure is a metal woven basket, a crocheted basket, or a metal support wrapped with a polymer filter membrane basket.

[0013] Optionally, when the foldable structure is in a folded state, a radial dimension of the catheter body is smaller than a radial dimension of the third channel of the catheter body.

[0014] Optionally, the flow-decelerating component comprises a folding frame and a flow-blocking film wrapped on the folding frame, and the flow-blocking film is provided with a flow-blocking surface on a side thereof that meets the impact of the fluid.

[0015] Optionally, the catheter body is further provided with a fourth channel for the optical fiber to pass through, the fourth channel is communicated with the balloon, and the proximal end of the optical fiber is connected to an external laser generator; and / or The fiber optic balloon catheter also includes a catheter seat, which is arranged at the proximal end of the catheter body. The catheter seat is provided with a plurality of interfaces or inlets which are in one-to-one communication with the inner cavity of the catheter body.

[0016] Optionally, the drug includes a photosensitizer, which is a naphthalimide dimer and its derivatives; the drug also includes a drug for inhibiting vascular restenosis, which is a macrolide immunosuppressant, a macrolide antibiotic, rapamycin, a structural derivative and functional analogue of rapamycin, everolimus, a structural derivative and functional analogue of everolimus, paclitaxel, taxanes, zotarolimus, sirolimus, biolimus, tacrolimus or temsirolimus or a temsirolimus compound.

[0017] In the technical solution of the present invention, the fiber optic balloon catheter includes a catheter body, a balloon, and a flow-slowing component; the balloon is arranged at the distal end of the catheter body, and the surface of the balloon is provided with medicine; at least in the process of transporting the balloon to the target part, the flow-slowing component is located on the side of the balloon that meets the impact of the fluid, and the flow-slowing component is used to slow down the scouring of the medicine on the balloon surface by the fluid during this process; wherein, when the fiber optic balloon catheter moves in the opposite direction relative to the fluid, the scouring side is the distal side of the balloon; when the fiber optic balloon catheter moves in the same direction relative to the fluid, the scouring side is the proximal side of the balloon. It can be understood that the present invention improves the structure of the fiber optic balloon catheter, slows down the scouring of the balloon by the fluid during the transportation of the fiber optic balloon catheter, and effectively reduces the loss of medicine on the balloon surface during transportation. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.

[0019] Figure 1 A schematic diagram of the structure and application of a first embodiment of a fiber optic balloon catheter of the present invention; Figure 2 A schematic diagram of the structure and application of a second embodiment of a fiber optic balloon catheter of the present invention; Figure 3 A schematic diagram of the structure and application of another embodiment of the fiber optic balloon catheter of the present invention; Figure 4 This is a schematic diagram of the structure and application of another embodiment of the fiber optic balloon catheter of the present invention.

[0020] Description of Figure Numbers: Ve, blood vessel; 10, catheter body; 20, balloon; 31, inflatable body; 32, foldable structure; 321, slow-flow guidewire; 331, folding frame; 332, flow-blocking film; 333, storage sleeve; 40, optical fiber; 50, catheter seat; 50a, balloon filling port; 50b, guidewire outlet; 50c, optical fiber inlet; 50d, inflatable body filling port; 50e, foldable structure inlet.

[0021] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] It should be noted that all directional indications (such as up, down, left, right, front, back, etc.) in the embodiments of the present invention are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0024] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0025] In addition, the descriptions of "first", "second", etc. in the present invention are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. The meaning of "and / or" appearing in the full text is that it includes three parallel solutions. Taking "A and / or B" as an example, it includes solution A, or solution B, or a solution that satisfies both A and B. The technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in this field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0026] The present invention provides a fiber optic balloon catheter, which can be used to deliver photosensitizers in cases of intravascular stenosis, and can also be used in other situations where balloons are required to deliver drugs, but the present invention is not limited here.

[0027] Reference Figures 1 to 4 In some embodiments of the present invention, the fiber optic balloon catheter includes a catheter body 10, a balloon 20 and a flow-reducing component; the balloon 20 is disposed at the distal end of the catheter body 10, and a drug is disposed on the surface of the balloon 20; at least in the process of delivering the balloon 20 to the target site, the flow-reducing component is located on the side of the balloon 20 that meets the impact of the fluid, and the flow-reducing component is used to slow down the scouring of the drug on the surface of the balloon 20 by the fluid during this process; wherein, when the fiber optic balloon catheter moves in the opposite direction relative to the fluid, the facing side is the distal side of the balloon 20; when the fiber optic balloon catheter moves in the same direction relative to the fluid, the facing side is the proximal side of the balloon 20.

[0028] In this embodiment, the slow-flow component can adopt an inflatable structure similar to the balloon 20 or a structure that can be automatically folded and unfolded, etc., which is not limited here. The slow-flow component has a larger flow blocking surface after being filled or unfolded, which can achieve a better effect of slowing down blood flow scour, and will not completely block the blood vessel Ve and cause danger. The slow-flow component is smaller in size when not filled or folded, which is conducive to the withdrawal of the fiber optic balloon catheter and also helps to save the cost of product packaging materials.

[0029] In this embodiment, the drug can be a drug coating applied on the surface of the balloon 20, or drug particles filled in several grooves on the surface of the balloon 20, or drug powder or tablets sandwiched between the folded wings of the balloon 20. The drug can include a photosensitizer to achieve interventional treatment of the blood vessel Ve; after the balloon 20 is expanded, the photosensitizer is released to the inner wall of the blood vessel Ve, and the optical fiber 40 emits light of a specific wavelength (400-500nm) to activate the photosensitizer, causing the amino acids on the inner wall of the blood vessel Ve to form covalent cross-links, which has a supporting effect on the blood vessel Ve, thereby avoiding the problem of blood vessel Ve retraction. Specifically, the photosensitizer can be a naphthalene imide dimer and its derivatives, which are not limited here.

[0030] In addition, a coating of a drug for inhibiting restenosis of the blood vessel Ve may be provided on the surface of the balloon 20, and the drug for inhibiting restenosis of the blood vessel Ve may be used to treat stenosis and occlusion of the blood vessel Ve, which helps to further improve the treatment effect. The drug for inhibiting restenosis of the blood vessel Ve may be a macrolide immunosuppressant, a macrolide antibiotic, rapamycin, a structural derivative and functional analogue of rapamycin, everolimus, a structural derivative and functional analogue of everolimus, paclitaxel, taxanes, zotarolimus, sirolimus, biolimus, tacrolimus or temsirolimus or a temsirolimus compound, etc.

[0031] It can be understood that the present invention improves the structure of the fiber optic balloon catheter, slows down the scouring of the balloon 20 by the fluid during the transportation of the fiber optic balloon catheter, and effectively reduces the loss of the drug on the surface of the balloon 20 during the transportation process.

[0032] In order to further enhance the effect of the slow flow component in slowing down the scouring of the fluid on the balloon 20, refer to Figure 1-Figure 4 In some embodiments, the radial dimension of the catheter body 10 when the slow flow component is in the working state is defined as a, and the radial dimension of the catheter body 10 when the balloon 20 is in the folded state is defined as b, and the following relationship is satisfied: b≤a <c; Where c is the inner diameter of human blood vessel Ve.

[0033] The present invention effectively avoids long-term blockage of blood vessel Ve during the delivery of the fiber optic balloon catheter by setting the radial dimension of the catheter body 10 of the slow-flow component in the working state to be smaller than the inner diameter of the blood vessel Ve, which can effectively avoid long-term blockage of blood vessel Ve and cause adverse reactions, ensuring the safety of the operation; and the present invention achieves a better slow-flow effect by setting the radial dimension of the catheter body 10 of the slow-flow component in the working state to be greater than or equal to the radial dimension of the catheter body 10 of the balloon 20 in the folded state, thereby avoiding excessive loss of drugs on the surface of the balloon 20 by being washed away by blood, greatly enhancing the treatment effect. It should be noted that for the prior art mentioned in the background technology, in the treatment stage, the drug balloon releases drugs for a relatively short time, and the short-term blockage of blood vessel Ve has little effect on the normal circulation of human blood. Therefore, the prior art of blocking blood vessel Ve by blocking balloon can be applied to this stage. However, the delivery process of the fiber optic balloon catheter takes a long time. If the prior art solution is applied to the delivery stage of the fiber optic balloon catheter discussed in the present invention, the blood vessel Ve will be blocked for a long time, the blood supply will be continuously interrupted, and a series of serious consequences will be caused.

[0034] In one embodiment, referring to Figure 1 and Figure 2 The slow-flow component is a fillable body 31, the catheter body 10 is provided with a first channel and a second channel both for introducing liquid, the balloon 20 is connected to the first channel, and the fillable body 31 is provided at the distal end of the catheter body 10 and is connected to the second channel.

[0035] like Figure 1 and Figure 2 As shown, when the fiber optic balloon catheter is designed to move in the opposite direction relative to blood or other fluids during the operation, the inflatable body 31 should be arranged on the distal side of the balloon 20; when the fiber optic balloon catheter is designed to move in the same direction relative to blood or other fluids during the operation, the inflatable body 31 should be arranged on the proximal side of the balloon 20.

[0036] In this embodiment, the projection of the fillable body 31 in the radial direction of the catheter body 10 can be circular, elliptical, peanut-shaped, "T"-shaped, umbrella-shaped or conical, etc., which is not limited here.

[0037] During the operation, the balloon 20 and the inflatable body 31 enter the blood vessel Ve under the guidance of the guidewire (the catheter body 10 is provided with a guidewire cavity and a guidewire inlet and a guidewire outlet 50b respectively connected to the guidewire cavity, the guidewire inlet is located at the farthest end of the catheter body 10, and the guidewire outlet 50b is located at the proximal end of the catheter body 10; the specific guidance process is: after the guidewire is positioned, the proximal end of the guidewire exposed outside the body is passed through the guidewire inlet at the farthest end of the fiber optic balloon catheter into the guidewire cavity and out of the guidewire outlet 50b, and then the fiber optic balloon catheter is pushed forward to make the balloon 20 enter the blood vessel Ve). At this time, the balloon 20 is in a folded state, and the fluid passes through the filling cavity from the inflatable body filling port 50d at the proximal end of the catheter body 10 to reach the inflatable body 31 to fill it. After the inflatable body 31 is filled, the outer diameter is small. Due to the outer diameter of the blood vessel Ve, during the transportation process, the fillable body 31 has the effect of slowing down the blood flow, so that the photosensitizer and other drugs on the surface of the balloon 20 will not be lost due to excessive flushing of the blood flow; when the balloon 20 reaches the diseased tissue, the balloon 20 begins to be filled, and the fluid reaches the balloon 20 from the balloon filling port 50a through the filling cavity of the balloon 20, so that the balloon 20 is filled, and the balloon 20 is brought into contact with the diseased tissue, and the photosensitizer reaches the diseased tissue; then, the laser generator controls the optical fiber 40 to emit light with a wavelength of 400-500nm to activate the photosensitizer, thereby inducing cross-linking of proteins in the wall of the blood vessel Ve, forming a natural blood vessel Ve stent, so that the expanded blood vessel Ve can be maintained; finally, the balloon 20 and the fillable body 31 are depressurized, so that they shrink and are withdrawn from the body.

[0038] In another embodiment, referring to Figure 3 , the slow-flow component is a foldable structure 32, the catheter body 10 is provided with a third channel for the slow-flow guide wire 321 to pass through, the third channel has an outlet located at the distal side of the balloon 20, and the foldable structure 32 is transported to the outside of the outlet of the third channel through the slow-flow guide wire 321 and automatically unfolds after leaving the outlet of the third channel. Among them, when the foldable structure 32 is in a folded state, the radial dimension of the catheter body 10 can be set to be smaller than the radial dimension of the third channel of the catheter body 10. The present invention adopts a foldable structure 32, which can make the structure of the fiber optic balloon catheter more compact, and each component or assembly can be produced in a modular manner, which is more convenient to manufacture, and the operation is also relatively simple during the operation.

[0039] In this embodiment, the foldable structure 32 can be a metal woven basket, a crocheted basket, or a metal support wrapped with a polymer filter membrane basket, etc., which is not limited here.

[0040] At the beginning of the procedure, the foldable structure 32 is in a contracted state, and will automatically expand when it is delivered to the distal side of the balloon 20. During the delivery process, the foldable structure 32 has a slowing effect on the blood flow, so that the photosensitizer on the surface of the balloon 20 will not be lost due to excessive flushing of the blood flow. Specifically, when the foldable structure 32 is pushed out from the outlet of the third channel through the slow-flow guide wire 321, it can be automatically expanded; when the drug delivery is completed, when the foldable structure 32 is withdrawn to the outlet position of the third channel, it can be automatically contracted under its obstruction, restored to a folded state, and withdrawn through the third channel.

[0041] During the operation, the balloon 20 enters the blood vessel Ve under the guidance of the guidewire (the catheter body 10 is provided with a guidewire cavity and a guidewire inlet and a guidewire outlet 50b respectively connected to the guidewire cavity, the guidewire inlet is located at the farthest end of the catheter body 10, and the guidewire outlet 50b is located at the nearest end of the catheter body 10; the specific guidance process is: after the guidewire is positioned, the nearest end of the guidewire exposed outside the body is passed through the guidewire inlet at the farthest end of the fiber optic balloon catheter into the guidewire cavity and out of the guidewire outlet 50b, and then the fiber optic balloon catheter is pushed forward to make the balloon 20 enter the blood vessel Ve). At this time, the foldable structure 32 is in a contracted state, and the foldable structure 32 is transported to the distal side of the balloon 20 through the entrance of the third channel (i.e., the foldable structure entrance 50e shown in the figure) through the slow-flow guidewire 321. After leaving the outlet, the foldable structure 32 automatically unfolds. The foldable structure 32 has an effect on blood flow The effect of slowing down the speed prevents the photosensitizer on the surface of the balloon 20 from being lost due to excessive flushing of the blood flow; when the balloon 20 reaches the diseased tissue, the fluid passes through the balloon 20 filling cavity from the balloon filling port 50a to reach the balloon 20, filling the balloon 20, thereby making the balloon 20 contact with the diseased tissue and allowing the photosensitizer to reach the diseased tissue; then, the optical fiber 40 is controlled by an external laser generator to emit light with a wavelength of 400-500nm to activate the photosensitizer, thereby initiating cross-linking of proteins in the wall of the blood vessel Ve, forming a natural blood vessel Ve stent, so that the expanded blood vessel Ve can be maintained; finally, the slow-flow guide wire 321 is pulled back to retract the foldable structure 32, and the foldable structure 32 will automatically fold when it touches the outlet of the third channel until the foldable structure 32 is completely withdrawn from the body; finally, the balloon 20 is depressurized to shrink, and then the balloon 20 is withdrawn from the body.

[0042] In yet another embodiment, referring to Figure 4 The flow-slowing component may also be a structure including a folding frame 331 and a flow-blocking film 332 wrapped on the folding frame 331. The flow-blocking film 332 is provided with a flow-blocking surface on its side facing the fluid impact. The flow-blocking surface may preferably be arc-shaped, so as to achieve the flow-slowing effect while avoiding damage caused by a large impact locally, which helps to improve its service life.

[0043] Similar to the above-mentioned inflatable body 31 solution, the slow-flow component composed of the folding frame 331 and the flow-blocking film 332 of this embodiment can be set at a specific location according to the specific application scenario of the fiber optic balloon catheter. When the fiber optic balloon catheter is designed to move in the opposite direction relative to blood or other fluids during the operation, the slow-flow component should be set at the distal side of the balloon 20; when the fiber optic balloon catheter is designed to move in the same direction relative to blood or other fluids during the operation, the slow-flow component should be set at the proximal side of the balloon 20.

[0044] In this embodiment, the folding frame 331 can be made of medical shape memory metal or plastic material, and the flow-blocking film 332 can be made of polymer material, etc., without specific limitation.

[0045] It can be understood that the fiber optic balloon catheter of the present invention, by providing the above-mentioned slow flow component, can slow down the scouring of the balloon 20 by blood during a long period of delivery, while effectively improving the convenience of the fiber optic balloon catheter delivery operation and improving the efficiency of the operation.

[0046] Furthermore, in order to ensure the smoothness of the fiber optic balloon catheter entering the blood vessel and being withdrawn after the treatment, in this embodiment, a storage sleeve 333 movable along its axial direction is sleeved on the outer periphery of the catheter body 10 for releasing and recovering the slow-flow component. The storage sleeve 333 can be moved and switched between a first position and a second position; in the first position, the slow-flow component is folded and stored in the storage sleeve 333 as a whole. In this state, the fiber optic balloon catheter has a smaller overall diameter, is more convenient to withdraw, and has a smaller packaging volume; in the second position, the slow-flow component is completely separated from the storage sleeve 333, and the folding frame 331 is automatically unfolded. In this embodiment, the storage sleeve 333 can be set as a manual control structure that can be manually pushed and pulled for axial movement, or it can be set as an automatic control structure that can be moved axially by pressing a button on the operating handle, which is not limited here.

[0047] In addition, in order to activate the photosensitizer during surgery and induce the formation of covalent cross-links of amino acids on the inner wall of vascular Ve, which has a supporting effect on vascular Ve and thus avoids the problem of vascular Ve retraction, refer to Figures 1 to 4 In the aforementioned embodiments, the catheter body 10 of the fiber optic balloon catheter can be provided with a fourth channel for the optical fiber 40 to pass through, the fourth channel is connected to the balloon 20, the proximal end of the optical fiber 40 is connected to an external laser generator, the optical fiber 40 enters the fourth channel through the optical fiber entrance 50c, and the distal end of the optical fiber 40 is arranged at the balloon 20.

[0048] In order to facilitate the connection of the laser generator, guide the balloon 20 to the lesion location, fill the balloon 20, fill the inflatable body 31, guide the foldable structure 32 to the distal side of the balloon 20, etc., so as to achieve interventional treatment and improve the efficiency of the operation, in this embodiment, the fiber optic balloon catheter can include a catheter seat 50, which is arranged at the proximal end of the catheter body 10, and the catheter seat 50 is provided with a plurality of interfaces or inlets that are one-to-one connected to the inner cavity of the catheter body 10. The number and type of interfaces or inlets can be determined according to the number and type of specific cavities (including but not limited to the first channel, the second channel, the third channel and the fourth channel) of the inner cavity of the catheter body 10, and are not limited here.

[0049] The above descriptions are only optional embodiments of the present invention, and are not intended to limit the patent scope of the present invention. All equivalent structural changes made using the contents of the present invention's specification and drawings, or directly / indirectly applied in other related technical fields, are included in the patent protection scope of the present invention.

Claims

1. A fiber optic balloon catheter, characterized in that: include: a catheter body; A balloon is arranged at the distal end of the catheter body, and a drug is arranged on the surface of the balloon; as well as A slow-flow component, at least in the process of delivering the balloon to the target site, the slow-flow component is located on the side of the balloon that meets the impact of the fluid, and the slow-flow component is used to slow down the scouring of the fluid on the drug on the surface of the balloon during this process; The slow-flow component is a foldable structure, the catheter body is provided with a third channel for the slow-flow guide wire to pass through, the third channel has an outlet located at the distal end of the balloon, the foldable structure is transported to the outside of the outlet of the third channel by the slow-flow guide wire and automatically unfolds after leaving the outlet of the third channel; or, the slow-flow component includes a folding frame and a flow-blocking film coated on the folding frame, the flow-blocking film is provided with a flow-blocking surface on its side facing the impact of the fluid, and a storage sleeve movable along its axial direction is sleeved on the outer periphery of the catheter body, and the storage sleeve is used to release and recover the slow-flow component; The radial dimension of the catheter body when the flow-slowing component is in the working state is defined as a, and the radial dimension of the catheter body when the balloon is in the folded state is defined as b, which satisfies the following relationship: b≤a <c; Where c is the inner diameter of human blood vessels; Wherein, when the fiber optic balloon catheter moves in reverse direction relative to the fluid, the welcoming side is the distal end side of the balloon; When the fiber optic balloon catheter moves in the same direction relative to the fluid, the meeting side is the proximal side of the balloon.

2. The fiber optic balloon catheter according to claim 1, characterized in that: The foldable structure is a metal woven basket, a hooked basket or a metal support wrapped with a polymer filter membrane basket.

3. The fiber optic balloon catheter according to claim 1, characterized in that: When the foldable structure is in a folded state, a dimension of the diametrical direction of the catheter body is smaller than a dimension of the third channel in the diametrical direction of the catheter body.

4. The fiber optic balloon catheter according to claim 1, characterized in that: The catheter body is further provided with a fourth channel for the optical fiber to pass through, the fourth channel is communicated with the balloon, and the proximal end of the optical fiber is connected to an external laser generator; and / or The fiber optic balloon catheter also includes a catheter seat, which is arranged at the proximal end of the catheter body. The catheter seat is provided with a plurality of interfaces or inlets which are in one-to-one communication with the inner cavity of the catheter body.

5. The fiber optic balloon catheter according to claim 4, characterized in that: The drug includes a photosensitizer, and the photosensitizer is a naphthalimide dimer and its derivatives; The drugs also include drugs for inhibiting vascular restenosis, which are macrolide immunosuppressants, macrolide antibiotics, rapamycin, structural derivatives and functional analogs of rapamycin, everolimus, structural derivatives and functional analogs of everolimus, paclitaxel, taxanes, zotarolimus, sirolimus, biolimus, tacrolimus or temsirolimus or temsirolimus compounds.

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