An antibody detection device

Abstract

The present application discloses an antibody detection device, which relates to the field of antibody detection technology, and includes a box body, in which a feed chamber, a detection chamber and a discharge chamber are sequentially formed, the box body is located in the detection chamber, and a carrier is provided in the feed chamber and the discharge chamber, a tray is placed on the carrier, and a sample box, a pipette tip box, a test kit and a test carrier are placed on the tray, a vibration component, a moving mechanism and a conveying mechanism are provided in the box body, and the moving end of the moving mechanism is provided with two pipettes, and the conveying mechanism is used to drive the tray in the feed chamber to move into the detection chamber, and the conveying mechanism is used to drive the tray in the detection chamber to move into the discharge chamber. The present application utilizes a conveying mechanism, and when the detection is completed, the conveying mechanism transfers the tray in the detection chamber to the carrier of the discharge chamber, and transfers the tray in the feed chamber to the carrier of the detection chamber, reducing the replacement time of the sample box, the pipette tip box, the test kit and the test carrier, thereby improving the detection efficiency of the antibody detection device.

Description

Technical Field

[0001] The present application relates to the technical field of antibody detection, and in particular to an antibody detection device. Background Art

[0002] Antibody testing equipment is used to detect specific antibodies in organisms. By collecting samples such as blood and serum, antibody testing equipment can quickly and accurately identify and quantify antibody levels using immunological principles. This equipment is widely used in disease diagnosis, epidemic monitoring, and immune response assessment.

[0003] At present, the antibody detection equipment includes a detection box, a carrier, a pipetting arm, a pipette, an oscillation module and a waste tank. After the box door is opened, the sample box, the tip box and the reagent kit are placed on the carrier. The pipetting arm drives the pipette to move, and the pipette will move into the tip box and drive the tips in the tip box to move. The tips move and absorb the samples and reagents in the sample box and the reagent kit respectively. The pipetting arm then drives the pipette to move above the oscillation module, and the pipette squeezes the samples and reagents in the tips into the detection carrier on the oscillation module. The oscillation module drives the detection carrier to vibrate and display the final test results.

[0004] After the test is completed, the staff opens the box door and needs to take out the sample box, tip box, reagent kit and test carrier in turn, and then put the replaced sample box, tip box, reagent kit and test carrier back into the box before conducting the test again, which will reduce the detection efficiency. Summary of the Invention

[0005] In order to improve the detection efficiency of an antibody detection device, the present application provides an antibody detection device.

[0006] The antibody detection device provided in this application adopts the following technical solution:

[0007] An antibody detection device includes a box body, a detection cavity is formed in the middle of the box body, a feed cavity and a discharge cavity are respectively formed on both sides of the box body located in the detection cavity, the box body is located in the detection cavity, and carriers are provided in the feed cavity and the discharge cavity, a tray is placed on the carrier, and a sample box, a tip box, a reagent kit and a detection carrier are placed on the tray, the box body is located in the detection cavity and a vibration component is provided, the box body is located in the detection cavity and a moving mechanism is provided, the moving end of the moving mechanism is provided with two pipettes, and a conveying mechanism is provided in the box body, the conveying mechanism is used to drive the tray in the feed cavity to move into the detection cavity, and the conveying mechanism is used to drive the tray in the detection cavity to move into the discharge cavity.

[0008] By adopting the above technical solution, the moving mechanism drives the pipette to move, and after the pipette is loaded with a pipette tip, it sucks up the sample and reagent, and transfers the sample and reagent to the detection carrier. The vibration component drives the detection carrier to vibrate and presents the test results. During the antibody detection process, the sample box, pipette tip box, reagent kit and detection carrier that need to be replaced are placed on the tray of the carrier in the feed chamber. When the test is completed, the transport mechanism transfers the tray in the detection chamber to the carrier of the discharge chamber, and transfers the tray in the feed chamber to the carrier of the detection chamber, reducing the replacement time of the sample box, pipette tip box, reagent kit and detection carrier, thereby improving the detection efficiency of the antibody detection equipment.

[0009] Preferably, the transport mechanism includes an X-axis moving assembly, a Y-axis moving assembly, a Z-axis moving assembly and a bracket, the Z-axis moving assembly is arranged in the detection cavity of the box, the X-axis moving assembly is arranged at the lifting end of the Z-axis moving assembly, the Y-axis moving assembly is arranged at the translation end of the X-axis moving assembly, the bracket is arranged at the translation end of the Y-axis moving assembly, and the bracket moves to lift the tray.

[0010] By adopting the above technical solution, the X-axis moving assembly and the Y-axis moving assembly drive the bracket to move under the pallet, and the Z-axis moving assembly drives the bracket to move upward so that the bracket lifts the pallet. After the bracket drives the pallet to move to the designated location, the Z-axis moving assembly drives the pallet to move downward and places the pallet on the carrier, thereby completing the transportation and movement of the pallet.

[0011] Preferably, a storage opening is provided in the bracket, the detection carrier is arranged in the storage opening of the bracket, a hook is provided on the detection carrier for sliding along its own thickness direction, the top of the hook is detachably inserted into the top wall of the bracket, a plurality of first limiting holes are provided on the bottom wall of the detection carrier, a vibration plate is provided on the top of the vibration assembly, a plurality of first limiting rods are provided on the top wall of the vibration plate, and the plurality of first limiting rods are inserted into the plurality of first limiting holes.

[0012] By adopting the above technical solution, the detection carrier is driven to move by the hook during the movement of the pallet. When the pallet is placed on the carrier in the detection chamber, the pallet drives the detection carrier to move to the vibration plate of the vibration assembly. The first limit rod on the vibration plate is inserted into the first limit hole of the detection carrier, so that the detection carrier is placed on the vibration plate more stably. After the detection carrier is placed on the vibration plate, the pallet continues to move downward and is placed on the carrier. At this time, the top of the hook will be separated from the pallet, so that the detection carrier is not connected to the pallet, which makes it easier for the vibration assembly to drive the detection carrier to vibrate stably.

[0013] Preferably, the first limit rod is rotatably arranged on the vibration plate, and an elastic reset member is provided at the rotation connection between the first limit rod and the vibration plate for driving the first limit rod to rotate and reset; a locking block is provided on the outer wall of the first limit rod, and the detection carrier is located on the inner wall of the first limit hole and is obliquely provided with a rotation groove; the detection carrier is located on one side of the top of the rotation groove and is provided with a locking groove connected to the rotation groove, and the locking block is slidably arranged in the rotation groove, and when the locking block slides to the top of the rotation groove, the elastic reset member drives the locking block to move into the locking groove through the first limit rod and locks the detection carrier.

[0014] By adopting the above technical solution, when the first limit rod on the vibration plate is inserted into the first limit hole of the detection carrier plate, the locking block on the first limit rod enters the rotation groove and slides. Since the rotation groove is inclined, the locking block will drive the first limit rod to rotate during the sliding process in the rotation groove. When the detection carrier plate is placed on the vibration plate, the locking block moves to the top of the rotation groove, and the elastic reset part drives the first limit rod to rotate and reset. The first limit rod drives the locking block to rotate into the locking groove, so that the locking block can lock the detection carrier plate on the vibration plate, thereby making the vibration plate drive the detection carrier plate to vibrate more stably.

[0015] Preferably, a guide ring is fixedly provided at the bottom of the outer wall of the hook, and a slide groove is provided in the detection carrier, and the guide ring is slidably arranged in the slide groove along the thickness direction of the detection carrier, and the detection carrier is slidably installed with a pull ring in the slide groove, and the pull ring is sleeved on the hook and located above the guide ring, and a pull rod is slidably installed in the detection carrier along its own thickness direction, and the top of the pull ring is fixedly connected to the pull ring, and the bottom end of the pull rod is formed with a chamfer on one side close to the locking block. When the tray moves upward, the top of the hook is inserted into the tray, and the tray drives the guide ring to rise through the hook, and the guide ring drives the pull rod to rise through the pull ring, and the pull rod enters the lock groove and pushes the lock block to slide out of the lock groove through the chamfer.

[0016] By adopting the above technical solution, when the inspection carrier is placed on the vibration plate, the hook is driven downward by gravity to drive the guide ring, and the pull ring and the pull rod are also driven downward by gravity to move, and the bottom end of the pull rod slides out of the lock slot, allowing the locking block to enter the lock slot. When the transport mechanism drives the pallet to move, the pallet moves upward, and the top end of the hook is inserted into the pallet. The pallet drives the guide ring upward through the hook, and the guide ring drives the pull rod upward through the pull ring. The pull rod enters the lock slot and pushes the locking block out of the lock slot through the chamfer, thereby unlocking the inspection carrier, allowing the pallet to drive the inspection carrier to move through the hook.

[0017] Preferably, an elastic member is provided in the detection carrier plate, a push plate is fixedly provided on the top end of the pull rod, the top end of the elastic member abuts against the inner wall of the detection carrier plate, and the bottom end abuts against the top wall of the push plate.

[0018] By adopting the above technical solution, when the detection carrier is placed on the vibration plate, the elastic member pushes the push plate to move, and the push plate drives the pull rod and the pull ring to move downward, so that the bottom end of the pull ring quickly moves out of the lock slot, thereby facilitating the locking block to enter the lock slot and lock the detection carrier.

[0019] Preferably, a plurality of second limiting rods are fixedly provided on the top wall of the bracket, a plurality of second limiting holes are opened on the bottom wall of the tray, and the plurality of second limiting rods are inserted into the plurality of second limiting holes.

[0020] By adopting the above technical solution, when the bracket lifts the pallet, the multiple second limiting rods on the bracket are inserted into the multiple second limiting holes on the bottom wall of the pallet, thereby limiting the pallet on the bracket, so that when the bracket drives the pallet to move, the pallet is not easily offset.

[0021] Preferably, a plurality of third limiting rods are fixedly provided on the top wall of the carrier, a plurality of third limiting holes are opened on the bottom wall of the tray, and the plurality of third limiting rods are inserted into the plurality of third limiting holes.

[0022] By adopting the above technical solution, when the pallet is placed on the carrier, the multiple third limiting rods on the carrier are inserted into the multiple third limiting holes on the bottom wall of the pallet, thereby limiting the pallet on the carrier, so that the pallet is not easily offset during the inspection process of the inspection equipment.

[0023] In summary, this application includes at least one of the following beneficial technical effects:

[0024] 1. Utilizing a transport mechanism, upon completion of testing, the transport mechanism transfers the tray in the testing chamber to the carrier of the discharge chamber, and the tray in the feed chamber to the carrier of the testing chamber, thereby reducing the time required to replace sample boxes, tip boxes, reagent kits, and test carriers, thereby improving the testing efficiency of the antibody testing equipment.

[0025] 2. With the help of the first limiting rod and the hook, when the pallet is placed on the carrier in the detection chamber, the pallet drives the detection carrier to move to the vibration plate of the vibration assembly. The first limiting rod on the vibration plate is inserted into the first limiting hole of the detection carrier, so that the detection carrier is placed on the vibration plate more stably. After the detection carrier is placed on the vibration plate, the pallet continues to move downward and is placed on the carrier. At this time, the top of the hook will be separated from the pallet, so that the detection carrier is not connected to the pallet, thereby facilitating the vibration assembly to drive the detection carrier to vibrate stably.

[0026] 3. Through the locking block, when the first limit rod on the vibration plate is inserted into the first limit hole of the detection carrier plate, the locking block on the first limit rod enters the rotation groove and slides. Since the rotation groove is inclined, the locking block will drive the first limit rod to rotate during the sliding process in the rotation groove. When the detection carrier plate is placed on the vibration plate, the locking block moves to the top of the rotation groove, and the elastic reset member drives the first limit rod to rotate and reset. The first limit rod drives the locking block to rotate into the locking groove, so that the locking block can lock the detection carrier plate on the vibration plate, thereby making the vibration plate more stable when driving the detection carrier plate to vibrate. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic diagram of the overall structure of the antibody detection device of this application;

[0028] Figure 2 This is a cross-sectional view of the overall structure of the antibody detection device of this application;

[0029] Figure 3 This is an exploded cross-sectional view of part of the structure of the antibody detection equipment of this application, highlighting the display tray;

[0030] Figure 4 This is an exploded cross-sectional view of part of the structure of the antibody detection device of this application, highlighting the detection carrier;

[0031] Figure 5 For this application Figure 2 A in the middle is an enlarged schematic diagram;

[0032] Figure 6 This is a partial structural cross-sectional view of the antibody detection device of this application, highlighting the transport mechanism;

[0033] Figure 7 For this application Figure 3 The enlarged schematic diagram of point B in the middle;

[0034] Figure 8 This is an exploded view of part of the structure of the antibody detection equipment in this application, to highlight the hook;

[0035] Figure 9 This is a partial structural cross-sectional view of the antibody detection device of the present application, highlighting the rotating tank;

[0036] Figure 10 This is a partial structural diagram of the antibody detection device of this application, highlighting the pull rod;

[0037] Figure 11 This is a partial structural diagram of the antibody detection device of this application, which highlights the positional relationship between the retractor hook and the locking block.

[0038] Figure 1: Box; 2: Detection chamber; 3: Feed chamber; 4: Discharge chamber; 5: Carrier; 6: Tray; 7: Transport mechanism; 71: X-axis moving assembly; 72: Y-axis moving assembly; 73: Z-axis moving assembly; 74: Bracket; 8: Sample box; 9: Tip box; 10: Reagent box; 11: Detection carrier; 12: Vibration assembly; 13: Pipette; 14: Storage port; 15: Hook; 16: First limiting hole; 17: Vibration plate; 18: First limiting rod; 19: Elastic reset member; 20: Lock block; 21: , rotating groove; 22, locking groove; 23, guide ring; 25, pull ring; 26, pull rod; 28, elastic part; 29, push plate; 30, second limiting rod; 31, second limiting hole; 32, third limiting rod; 33, third limiting hole; 34, first door body; 35, second door body; 36, third door body; 37, fourth door body; 38, fifth door body; 39, purification air supply mechanism; 40, air outlet; 41, waste box; 42, pull hook; 43, moving mechanism; 44, lifting assembly; 45, chamfer; 46, guide block. DETAILED DESCRIPTION

[0039] The following is combined with Figures 1-11 This application is described in further detail.

[0040] The embodiments of the present application disclose an antibody detection device.

[0041] Reference Figure 1 and Figure 2 An antibody detection device includes a box body 1, a detection chamber 2 is formed in the middle of the box body 1, a feed chamber 3 and a discharge chamber 4 connected to the detection chamber 2 are respectively formed on both sides of the box body 1 in the horizontal direction, and a first door body 34, a second door body 35 and a third door body 36 are rotatably installed at the detection chamber 2, the feed chamber 3 and the discharge chamber 4 of the box body 1.

[0042] Reference Figure 2 、 Figure 3 and Figure 4 The box body 1 is fixedly mounted with a carrier 5 in each of the feed chamber 3, the detection chamber 2, and the discharge chamber 4. A tray 6 is detachably placed on the carrier 5. Four third limiting rods 32 are fixedly mounted on the top wall of the carrier 5. Four third limiting holes 33 are formed on the bottom wall of the tray 6. The four third limiting rods 32 are respectively inserted into the four third limiting holes 33, ensuring that the tray 6 is stably placed on the carrier 5.

[0043] A test carrier 11, multiple reagent kits 10, a sample box 8, and a tip box 9 are placed on the tray 6. A vibration assembly 12 is installed in the carrier 5 of the detection chamber 2 of the box body 1. The vibration assembly 12 is located directly below the test carrier 11. A vibration plate 17 is fixedly mounted on the top of the vibration assembly 12, and four first limiting rods 18 are fixedly mounted on the vibration plate 17. Four first limiting holes 16 are opened on the bottom wall of the test carrier 11. The four first limiting rods 18 are respectively inserted into the four first limiting holes 16, so that the test carrier 11 is stably placed on the vibration plate 17. In this application, the vibration assembly 12 can be optionally used as an oscillator.

[0044] Reference Figure 2 and Figure 5 The box 1 is located in the detection chamber 2 and is equipped with a moving mechanism 43. Two lifting assemblies 44 are installed on the moving end of the moving mechanism 43. The lifting ends of the two lifting assemblies 44 are fixedly mounted with a pipette 13. In this application, the moving mechanism 43 can be selected as a three-axis slide, and the moving mechanism 43 can drive the pipette 13 to move freely in the XYZ axis direction. The lifting assembly 44 can be selected as a linear module, and the lifting assembly 44 can drive the pipette 13 to move up and down.

[0045] Reference Figure 2 、 Figure 3 and Figure 5 When performing antibody testing on a sample, the moving mechanism 43 first drives the pipette 13 to the top of the tip box 9. The lifting assembly 44 then drives the pipette 13 downward, so that the tips in the tip box 9 are mounted on the bottom of the two pipettes 13. The lifting assembly 44 then drives the pipette 13 upward to reset. The moving mechanism 43 then drives the pipette 13 to the top of the sample box 8. One lifting assembly 44 drives the pipette 13 up and down, and the pipette 13 draws the sample liquid in the sample box 8 into one tip. The moving mechanism 43 then drives the pipette 13 to the top of the test box. The other lifting assembly 44 drives the other pipette 13 up and down, and the other pipette 13 draws the reagent in the test kit 10 into the other tip.

[0046] Finally, the moving mechanism 43 drives the pipette 13 to move above the test carrier 11. The pipette 13 squeezes the sample liquid and reagent into the test carrier 11. The vibration component 12 then drives the test carrier 11 to vibrate through the vibration plate 17, thereby displaying the antibody test results. A waste box 41 is placed in the test chamber 2 of the casing 1, and the top of the waste box 41 is opened. After the pipette 13 squeezes out the sample liquid and reagent, the moving mechanism 43 drives the pipette 13 to move above the waste box 41. The pipette 13 pushes the two tips into the waste box 41, and the above steps can be repeated to perform antibody testing again.

[0047] Reference Figure 2 and Figure 6A transport mechanism 7 is installed in the box 1. The transport mechanism 7 includes an X-axis moving assembly 71, a Y-axis moving assembly 72, a Z-axis moving assembly 73, and a bracket 74. The Z-axis moving assembly 73 is installed in the bottom wall of the box 1 located in the detection chamber 2. The X-axis moving assembly 71 is installed at the lifting end of the Z-axis moving assembly 73 and is slidably installed in the bottom wall of the box 1. The Y-axis moving assembly 72 is installed at the translation end of the X-axis moving assembly 71, and the bracket 74 is fixedly installed at the translation end of the Y-axis moving assembly 72. In this application, both the X-axis moving assembly 71 and the Y-axis moving assembly 72 can be selected as linear modules, and the Z-axis moving assembly 73 can be selected as two hydraulic cylinders.

[0048] The X-axis moving assembly 71 and the Y-axis moving assembly 72 can drive the bracket 74 to move freely on the horizontal plane, and the Z-axis moving assembly 73 can drive the bracket 74 to move up and down, so that the two ends of the bracket 74 can simultaneously hold up the tray 6 in the feed chamber 3 and the detection chamber 2, and transport the tray 6 to the carrier 5 of the detection chamber 2 and the discharge chamber 4. When the test is completed, the transport mechanism 7 transfers the tray 6 in the detection chamber 2 to the carrier 5 of the discharge chamber 4, and simultaneously transfers the tray 6 in the feed chamber 3 to the carrier 5 of the detection chamber 2, thereby reducing the replacement time of the sample box 8, the pipette tip box 9, the reagent box 10 and the detection carrier plate 11, thereby improving the detection efficiency of the antibody detection device.

[0049] Reference Figure 4 and Figure 6 Eight second limiting rods 30 are fixedly mounted on both ends of the top wall of the bracket 74 in the longitudinal direction, and four second limiting holes 31 are formed on the bottom wall of the tray 6. When the bracket 74 lifts the tray 6, the four second limiting rods 30 are inserted into the four second limiting holes 31 on the bottom wall of the tray 6, thereby limiting the position of the tray 6 and making the movement of the tray 6 driven by the bracket 74 more stable.

[0050] Reference Figure 1 and Figure 2 A fourth door 37 is installed in the housing 1, which is positioned between the detection chamber 2 and the feed chamber 3 and is thereby lifted and slidably mounted. A fifth door 38 is installed in the housing 1, which is positioned between the detection chamber 2 and the discharge chamber 4 and is thereby lifted and slidably mounted. A purification air supply mechanism 39 is installed at the top of the housing 1, above the detection chamber 2. In this application, the purification air supply mechanism 39 may be an FFU laminar flow air supply unit. Multiple air outlets 40 are spaced apart on the side walls of the housing 1, which are located away from each other at the feed chamber 3 and the discharge chamber 4.

[0051] During the antibody test, the fourth door 37 is closed, the fifth door 38 is opened, and the bracket 74 is located within the test chamber 2 and the discharge chamber 4. The purified air supply mechanism 39 delivers purified air into the test chamber 2, which is then discharged from the air outlet 40 at the bottom of the discharge chamber 4. At this point, the second door 35 can be opened, and the next set of sample boxes 8, pipette tip boxes 9, reagent cartridges 10, and test carrier plates 11 to be tested can be placed on the tray 6, which is then placed on the carrier 5 of the feed chamber 3.

[0052] Then, the second door 35 is closed, the fourth door 37 is opened, the bracket 74 is moved into the feed chamber 3 and the detection chamber 2, and the fifth door 38 is closed. The third door 36 is opened, and the tray 6 on the carrier 5 in the discharge chamber 4 is removed. During the antibody detection process, the tray 6 in the feed chamber 3 and the discharge chamber 4 can be replaced, further improving the efficiency of the antibody detection. At the same time, during the replacement of the tray 6, the purification air supply mechanism 39 sends the purified air into the detection chamber 2. By alternating the opening and closing of the fourth door 37 and the fifth door 38, the detection chamber 2 is always isolated from the outside air, thereby making the detection environment less susceptible to contamination.

[0053] Reference Figure 8 、 Figure 9 and Figure 10 A rectangular storage opening 14 is provided in the tray 6, and the detection carrier 11 is located in the storage opening 14 of the tray 6. Four hooks 15 are slidably mounted on the detection carrier 11 along its thickness direction, and the tops of the four hooks 15 are removably inserted into the top wall of the tray 6. Two guide blocks 46 are symmetrically fixedly mounted on the outer side wall of the hook 15. The guide blocks 46 are slidably mounted in the detection carrier 11 and prevent the hook 15 from rotating when it is raised or lowered. A guide ring 23 is fixedly mounted on the side wall of the hook 15 located in the detection carrier 11. A slide groove is provided in the detection carrier 11. The guide ring 23 is slidably mounted in the slide groove along the thickness direction of the detection carrier 11, so that the hook 15 will not slip out of the detection carrier 11.

[0054] Reference Figure 3 、 Figure 8 、 Figure 9 and Figure 10During the movement, the tray 6 can drive the detection carrier 11 to move through the four hooks 15. When the bracket 74 drives the tray 6 to be placed on the carrier 5 in the detection chamber 2, the tray 6 drives the detection carrier 11 to move downward. The detection carrier 11 first moves to contact the vibration plate 17 and stops moving. Then the tray 6 continues to move downward and drives the hook 15 to move downward. The hook 15 drives the guide ring 23 to move downward in the chute. When the guide ring 23 moves to the bottom of the chute, the hook 15 can no longer move downward. Finally, the tray 6 continues to move downward to contact the carrier 5 and stop moving. The top of the hook 15 will detach from the tray 6, so that the detection carrier 11 is not connected to the tray 6, so that the vibration component 12 drives the detection carrier 11 to vibrate. The vibration of the detection carrier 11 will not be transmitted to the tray 6, thereby facilitating the stable vibration of the detection carrier 11.

[0055] Reference Figure 7 The first limiting rod 18 is rotatably mounted on the vibration plate 17. An elastic return member 19 is installed at the rotational connection between the first limiting rod 18 and the vibration plate 17. In this application, the elastic return member 19 can be a torsion spring. Two locking blocks 20 are symmetrically fixedly mounted on the outer wall of the first limiting rod 18 along its own diameter.

[0056] Reference Figure 7 and Figure 9 The detection carrier plate 11 is located on the inner wall of the first limiting hole 16 and has two rotation slots 21 symmetrically defined along the diameter of the first limiting hole 16. The lower half of the rotation slots 21 are inclined. A locking slot 22 is defined at the top of the rotation slot 21 of the detection carrier plate 11. The locking slot 22 is located on the side of the top of the rotation slot 21 away from the inclined direction and communicates with the rotation slot 21. Two locking blocks 20 are slidably mounted within the two rotation slots 21 and the locking slot 22.

[0057] When the test carrier 11 is placed on the vibration plate 17, the first limiting rod 18 enters the first limiting hole 16, and the two locking blocks 20 enter the two rotation slots 21. As the test carrier 11 descends, the locking blocks 20 slide in the rotation slots 21, and the rotation slots 21 drive the first limiting rod 18 to rotate through the locking blocks 20, causing the first limiting rod 18 to deform the elastic return member 19. After the test carrier 11 is placed on the vibration plate 17, the locking blocks 20 slide to the top of the rotation slot 21, and the elastic return member 19 drives the first limiting rod 18 to rotate and reset. The first limiting rod 18 drives the two locking blocks 20 to rotate and enter the two locking slots 22, thereby locking the test carrier 11 on the vibration plate 17, making the test carrier 11 more stable when vibrating.

[0058] Reference Figure 9 、 Figure 10 and Figure 11A pull ring 25 is slidably mounted on the hook 15. The pull ring 25 is slidably mounted in the slide groove of the detection carrier 11, and the pull ring 25 is located above the guide ring 23. Pull rods 26 are slidably mounted on both sides of the pull ring 25 in the diameter direction of the detection carrier 11. The pull rods 26 slide in the detection carrier 11 along the thickness direction of the detection carrier 11. A push plate 29 is fixedly mounted on the top of the pull rods 26, and the push plate 29 is fixedly connected to the pull ring 25. An elastic member 28 is installed in the detection carrier 11. The top end of the elastic member 28 abuts the inner wall of the detection carrier 11, and the bottom end of the elastic member 28 abuts the top wall of the push plate 29. In this application, the elastic member 28 can be optionally used as a spring.

[0059] Reference Figure 10 and Figure 11 A hook 42 is formed at the bottom of the pull rod 26, and the hook 42 is located below the lock slot 22. The pull rod 26 can slide into and out of the lock slot 22 in the vertical direction, and a chamfer 45 is formed on one side of the hook 42 close to the locking block 20.

[0060] When the inspection carrier 11 is suspended in the tray 6 by the hook 15, the push plate 29 moves upward and presses the elastic member 28, and the push plate 29 drives the hook 42 to move into the lock slot 22 through the pull rod 26. When the inspection carrier 11 is placed on the vibration plate 17, the elastic member 28 pushes the push plate 29 downward, and the push plate 29 drives the pull rod 26 and the pull ring 25 downward. The pull ring 25 drives the hook 42 downward, so that the hook 42 quickly moves out of the lock slot 22, thereby facilitating the locking block 20 to enter the lock slot 22 and lock the inspection carrier 11.

[0061] When the transport mechanism 7 drives the pallet 6 to move, the pallet 6 moves upward, and the top end of the hook 15 is first inserted into the pallet 6. The pallet 6 drives the guide ring 23 to rise through the hook 15. The guide ring 23 drives the pull rod 26 to rise through the pull ring 25. The pull rod 26 then drives the hook 42 to move upward into the lock slot 22. The hook 42 pushes the locking block 20 to slide out of the lock slot 22 through the chamfer 45, thereby unlocking the detection carrier 11, so that the pallet 6 can drive the detection carrier 11 to move upward through the hook 15.

[0062] The implementation principle of an antibody detection device according to an embodiment of the present application is as follows: when performing antibody detection on a sample, the moving mechanism 43 first drives the pipette 13 to move above the tip box 9, and the lifting assembly 44 then drives the pipette 13 to move downward, so that the tips in the tip box 9 are installed at the bottom of the two pipettes 13, and then the lifting assembly 44 drives the pipette 13 to rise and reset. The moving mechanism 43 then drives the pipette 13 to move above the sample box 8, and one lifting assembly 44 drives the pipette 13 to move up and down, and the pipette 13 absorbs the sample liquid in the sample box 8 into one tip. The moving mechanism 43 then drives the pipette 13 to move above the test box, and another lifting assembly 44 drives another pipette 13 to move up and down, and the other pipette 13 absorbs the reagent in the reagent box 10 into another tip. Finally, the moving mechanism 43 drives the pipette 13 to move above the test carrier 11. The pipette 13 squeezes the sample liquid and reagent into the test carrier 11. The vibration component 12 then drives the test carrier 11 to vibrate via the vibration plate 17, thereby displaying the antibody test results. After the test is completed, the transport mechanism 7 transfers the tray 6 in the test chamber 2 to the carrier 5 of the discharge chamber 4. At the same time, the tray 6 in the feed chamber 3 is transferred to the carrier 5 of the test chamber 2. This reduces the replacement time of the sample box 8, the pipette tip box 9, the reagent box 10, and the test carrier 11, thereby improving the detection efficiency of the antibody detection equipment.

[0063] The above are merely optional embodiments of the present disclosure and are not intended to limit the present disclosure. Those skilled in the art will readily appreciate that the present disclosure may be modified and varied in various ways. Any modifications, equivalent substitutions, improvements, and the like made within the spirit and principles of the present disclosure shall be included within the scope of protection of the present disclosure.

Claims

1. An antibody detection device, characterized in that: The invention comprises a box body (1), wherein a detection chamber (2) is formed in the middle of the box body (1), and a feeding chamber (3) and a discharging chamber (4) are respectively formed on both sides of the box body (1) located at the detection chamber (2), the feeding chamber (3) and the discharging chamber (4), wherein a carrier (5) is provided in the box body (1) and the detection chamber (2), the feeding chamber (3) and the discharging chamber (4), and a tray (6) is placed on the carrier (5), and a sample box (8), a suction head box (9), a reagent box (10) and a detection carrier plate (11) are placed on the tray (6), and the box body (1 ) is provided with a vibration component (12) in the detection chamber (2), the box (1) is provided with a moving mechanism (43) in the detection chamber (2), the moving end of the moving mechanism (43) is provided with two pipettes (13), the box (1) is provided with a transport mechanism (7), the transport mechanism (7) is used to drive the tray (6) in the feed chamber (3) to move into the detection chamber (2), and the transport mechanism (7) is used to drive the tray (6) in the detection chamber (2) to move into the discharge chamber (4); The transport mechanism (7) includes an X-axis moving assembly (71), a Y-axis moving assembly (72), a Z-axis moving assembly (73) and a bracket (74); the Z-axis moving assembly (73) is arranged in the detection chamber (2) of the box (1); the X-axis moving assembly (71) is arranged at the lifting end of the Z-axis moving assembly (73); the Y-axis moving assembly (72) is arranged at the translation end of the X-axis moving assembly (71); the bracket (74) is arranged at the translation end of the Y-axis moving assembly (72); and the bracket (74) moves to lift the tray (6); A storage opening (14) is provided in the bracket (74), the detection carrier (11) is arranged in the storage opening (14) of the bracket (74), a hook (15) is provided on the detection carrier (11) so as to slide along its thickness direction, the top of the hook (15) is detachably inserted into the top wall of the bracket (74), a plurality of first limiting holes (16) are provided on the bottom wall of the detection carrier (11), a vibration plate (17) is provided on the top of the vibration assembly (12), a plurality of first limiting rods (18) are provided on the top wall of the vibration plate (17), and the plurality of first limiting rods (18) are inserted into the plurality of first limiting holes (16); The first limiting rod (18) is rotatably arranged on the vibration plate (17); an elastic reset member (19) for driving the first limiting rod (18) to rotate and reset is arranged at the rotation connection between the first limiting rod (18) and the vibration plate (17); a locking block (20) is arranged on the outer side wall of the first limiting rod (18); a rotation groove (21) is obliquely opened on the inner side wall of the first limiting hole (16); a locking groove (22) is opened on one side of the detection carrier (11) located at the top of the rotation groove (21) and connected to the rotation groove (21); the locking block (20) is slidably arranged in the rotation groove (21); when the locking block (20) slides to the top of the rotation groove (21), the elastic reset member (19) drives the locking block (20) to move into the locking groove (22) through the first limiting rod (18) and locks the detection carrier (11).

2. An antibody detection device according to claim 1, characterized in that: A guide ring (23) is fixedly provided at the bottom of the outer wall of the hook (15), a slide groove is provided in the detection carrier (11), the guide ring (23) is slidably provided in the slide groove along the thickness direction of the detection carrier (11), the detection carrier (11) is located in the slide groove and is slidably provided with a pull ring (25), the pull ring (25) is sleeved on the hook (15) and is located above the guide ring (23), a pull rod (26) is slidably provided in the detection carrier (11) along its own thickness direction, the pull ring (25) is slidably provided in the detection carrier (11) ) is fixedly connected to the pull ring (25), and the bottom end of the pull rod (26) is formed with a chamfer (45) on one side close to the locking block (20). When the tray (6) moves upward, the top end of the hook (15) is inserted into the tray (6), and the tray (6) drives the guide ring (23) to rise through the hook (15), and the guide ring (23) drives the pull rod (26) to rise through the pull ring (25), and the bottom end of the pull rod (26) enters the locking groove (22) and pushes the locking block (20) to slide out of the locking groove (22) through the chamfer (45).

3. An antibody detection device according to claim 2, characterized in that: An elastic member (28) is provided in the detection carrier plate (11), and a push plate (29) is fixedly provided at the top end of the pull rod (26). The top end of the elastic member (28) abuts against the inner wall of the detection carrier plate (11), and the bottom end abuts against the top wall of the push plate (29).

4. The antibody detection device according to claim 1, characterized in that: A plurality of second limiting rods (30) are fixedly provided on the top wall of the bracket (74), a plurality of second limiting holes (31) are opened on the bottom wall of the tray (6), and the plurality of second limiting rods (30) are inserted into the plurality of second limiting holes (31).

5. The antibody detection device according to claim 1, characterized in that: A plurality of third limiting rods (32) are fixedly provided on the top wall of the carrier (5), a plurality of third limiting holes (33) are opened on the bottom wall of the tray (6), and the plurality of third limiting rods (32) are inserted into the plurality of third limiting holes (33).

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