Preparation method of folic acid antioxidant microcapsule

Abstract

The invention aims to provide a preparation method of folic acid antioxidant microcapsules, and aims to solve the problem that folic acid is easy to oxidize in the prior art. Relates to a preparation method of folic acid antioxidant microcapsules, and belongs to the technical field of medicines, health care and foods. The preparation method comprises the following steps: dissolving folic acid in water containing an antioxidant and gelatin, emulsifying the water-soluble mixture, and dissolving in vegetable oil; a microcapsule structure of gelatin, vegetable oil, an antioxidant and folic acid is formed. The core material of the microcapsule is folic acid, the capsule material is vegetable oil, and the wall material is gelatin, so that the problem of rapid oxidation of folic acid in the processing process of 100 DEG C is effectively solved.

Description

1. Technical Field

[0001] The invention relates to a method for preparing folic acid antioxidant microcapsules, belonging to the technical fields of medicine, health care and food. 2. Technical Background

[0002] Folic acid is an essential nutrient for the human body, especially for pregnant women and fetuses. However, folic acid is easily oxidized during storage and cooking, thus losing its nutritional value. Therefore, it is of great significance to develop a microencapsulation solution that can protect folic acid from oxidation. 3. Summary of the invention

[0003] The purpose of the present invention is to provide a method for preparing folic acid antioxidant microcapsules, aiming to solve the problem that folic acid is easily oxidized in the prior art.

[0004] 4. Technical solution

[0005] The preparation method of a folic acid antioxidant microcapsule of the present invention comprises the following steps:

[0006] (1) dissolving folic acid powder in water containing a water-soluble antioxidant and 1% gelatin to form a mixture (A); heating the mixture to 85 degrees Celsius;

[0007] (2) mixing vegetable oil, soybean lecithin and glyceryl monostearate together to form a mixture (B); heating the mixture to 85 degrees Celsius; the amount of vegetable oil and emulsifier used is twice that of the folic acid aqueous solution mixture;

[0008] (3) mixing (1) and (2) at 85 degrees Celsius, emulsifying and mixing by a colloid mill or a vacuum emulsifier, and cooling to room temperature to form microcapsules;

[0009] (4) Cooling the microcapsules to room temperature to obtain folic acid antioxidant oil-soluble microcapsules.

[0010] (5) The microcapsules prepared in (4) can also be mixed with twice the amount of aqueous solution containing 10% to 30% maltodextrin, and spray-dried to obtain water-soluble antioxidant dry powder of folic acid microcapsules.

[0011] In the present invention, the antioxidant may be vitamin C, vitamin E or a mixture thereof. In addition, one or more emulsifiers may be added in step (2), wherein the HLB value of the emulsifier is 1 to 20, so as to improve the stability of the microcapsules.

[0012] 5. Invention Advantages

[0013] The method for preparing the folic acid antioxidant microcapsules of the present invention can effectively protect folic acid from the influence of oxidation and heating, improve the stability of folic acid, and prolong its storage time. In addition, the scheme is simple to operate and can be industrially produced.

[0014] 6. Implementation Method

[0015] The present invention is described in detail below with reference to examples.

[0016] (1) 100 g of folic acid powder, 50 g of vitamin C and 1 g of gelatin aqueous solution were mixed to form a mixture (A); and the mixture was heated to 85° C.;

[0017] (2) adding an emulsifier to a total of 302 g of vegetable oil, wherein the vegetable oil is 300 g, and the emulsifier is 1 g of glyceryl monostearate and 1 g of soybean lecithin, to obtain a mixture (B); heating the mixture to 85° C. and maintaining the mixture for 5 minutes;

[0018] (3) emulsifying the mixture (A) and (B) prepared in (1) and (2) by using a colloid mill or by using a vacuum emulsifier for emulsification at 85° C. for 40 minutes to obtain folic acid oil-soluble microcapsules;

[0019] (4) Cooling the microcapsules to room temperature to obtain folic acid antioxidant oil-soluble microcapsules, which are then bagged and set aside for use.

[0020] (5) The folic acid oil-soluble microcapsules prepared in (4) and 2 kg of a 30% maltodextrin aqueous solution were mixed at room temperature, and then spray-dried at an inlet air temperature of 200° C. and an exhaust air temperature of 60° C. to obtain folic acid water-soluble microcapsule dry powder. 7. Specific embodiments

[0021] The preparation method of the folic acid antioxidant microcapsules of the present invention can be applied to various foods, health products and medicines, and will be described below in conjunction with specific embodiments.

[0022] Example 1: The folic acid antioxidant microcapsules prepared in (5) above were added to milk powder for pregnant women, and the production and packaging were carried out according to conventional methods.

[0023] Example 2: The folic acid antioxidant microcapsules prepared in (4) above were added to biscuits as food additives and produced and packaged according to conventional methods.

[0024] Example 3: The folic acid antioxidant microcapsules prepared in (5) above were added as drug ingredients to an anti-anemia drug, and the drug was produced and packaged according to conventional methods.

[0025] Example 4: The folic acid antioxidant microcapsules prepared in (5) above are added to the fermented wheat flour as a nutritional enhancer, and the flour is produced and packaged according to conventional production methods to obtain folic acid steamed bread.

[0026] Example 5: The folic acid antioxidant microcapsules prepared in (4) above are added to wheat flour as a nutritional enhancer, and the wheat flour is produced and packaged according to conventional methods. Thus, folic acid-enriched wheat flour can be obtained, and people can consume it in their daily diet after conventional processing.

Claims

1. A method for preparing folic acid antioxidant microcapsules Features The following steps are involved: (1) dissolving folic acid powder in water containing a water-soluble antioxidant and 1% gelatin to form a mixture (A); heating the mixture to 85 degrees Celsius; (2) mixing vegetable oil, soybean lecithin and glyceryl monostearate together to form a mixture (B); heating the mixture to 85 degrees Celsius; The amount of vegetable oil and emulsifier used is twice that of the folic acid aqueous solution mixture; (3) mixing (1) and (2) at 85 degrees Celsius, emulsifying and mixing by a colloid mill or a vacuum emulsifier, and cooling to room temperature to form microcapsules; (4) Cooling the microcapsules to room temperature to obtain folic acid antioxidant oil-soluble microcapsules. (5) The microcapsules prepared in step (4) and twice the amount of aqueous solution containing 10% to 30% maltodextrin can also be spray-dried to obtain water-soluble antioxidant dry powder of folic acid microcapsules.