A magnetic levitation heart pump system based on nuclear battery power supply and a control method thereof

Abstract

The present application relates to the technical field of implantable artificial heart pump, in particular to a magnetic suspension heart pump system based on nuclear battery power supply and a control method thereof. The device breaks through the dependence of traditional artificial heart on external power supply by the fusion of nuclear energy-capacitor hybrid power supply system and intelligent control technology, and realizes lifelong physiological level circulation support. The core innovation includes: adopting beta radiation isotope diamond semiconductor packaging technology to construct a micro nuclear battery group, combining a super capacitor to form a dual-mode energy network, ensuring radiation safety while achieving dynamic balance of energy density and power output; based on the third generation centrifugal pump body optimized by magnetic suspension bearing and fluid mechanics, the personalized pump cavity structure is constructed by biocompatible materials to form a non-contact blood driving system; the pump body working state is dynamically optimized by real-time monitoring of hemodynamic parameters and metabolic indicators.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of implantable artificial heart pumps, in particular to a magnetic suspension heart pump system based on nuclear battery power supply and a control method thereof. BACKGROUND

[0002] As a long-life power supply device, nuclear batteries were early mainly applied to space exploration (such as radioisotope thermoelectric generator, RTG) and deep sea equipment. The core principle is to release energy through radioactive isotope decay and convert it into electrical energy. However, traditional nuclear batteries (such as RTG) are difficult to meet the stringent requirements of medical implant devices due to problems such as large size, complex radiation protection, and low energy density. For example, the typical power output of RTG is tens to hundreds of watts, but its heat management requirements result in a volume far exceeding the implantable range of the human body.

[0003] In recent years, Betavoltaic Battery has attracted attention due to its low radiation characteristics, which directly generates electrical energy using beta particles (such as nickel-63 decay). However, the power density of existing Betavoltaic Battery is generally insufficient (usually less than 1 milliwatt per cubic centimeter), which cannot meet the basic power requirements (5-15 watts) of medical devices such as heart pumps, and heart pumps need to adapt to the instantaneous changes in blood flow (such as 20-watt peak power during exercise), and existing nuclear batteries cannot independently support such requirements. In addition, the lack of radiation shielding technology further limits its safe application in the human body.

[0004] Since the first clinical implant by the Kolff team in 1964, artificial heart pumps (Ventricular Assist Devices, VAD) have undergone three generations of technological innovation: the first generation of pulsatile pumps (such as Novacor) simulate heart contraction through diaphragm mechanical compression, the second generation of axial flow pumps (such as HeartMate II) use impeller structure to significantly reduce volume, and the third generation of magnetic suspension centrifugal pumps (such as HeartMate 3) achieve non-contact bearing design. Although technological iteration has increased 5-year survival rate from 20% to 70%, there are still core bottlenecks:

[0005] Limited power supply mode: dependent on external lithium battery connected through percutaneous lead, leading to infection risk (incidence 10%-20%), and frequent battery replacement seriously affects patient quality of life.

[0006] Thrombosis and flow control accuracy problems: pump cavity flow channel design is not fully optimized, and turbulent flow exacerbates thrombosis risk; existing control algorithms cannot match patient physiological state (such as exercise or sleep) in real time, easily leading to insufficient blood supply or excessive pumping.

[0007] The development of nuclear-powered heart pumps is limited by the power supply technology, and the prototype of nuclear-powered heart pumps can be traced back to nuclear-powered pacemakers. In recent years, the research of nuclear-powered heart pumps focuses on combining miniature radioisotope thermoelectric generators (RTG) with ventricular assist devices (VAD), trying to achieve long-term maintenance-free operation through isotope decay power supply. The technical bottleneck mainly lies in that the power output of the miniature RTG is restricted by the isotope decay characteristics. In addition, the thermoelectric conversion efficiency of the RTG (usually 5%-12%) limits the power density, and the supercapacitor or flywheel energy storage system needs to be combined to buffer the instantaneous load demand, but the volume and weight of such hybrid energy systems still exceed the human body implantation limit.

[0008] The current technology faces the "energy-safety-volume" triple contradiction: isotope dilemma: high-energy isotopes require complex shielding, and low-risk isotopes are insufficient for power supply; heat management paradox: Stirling engine requires a temperature difference of >200℃ to maintain efficiency, but the heat tolerance threshold of human tissues is only 50℃. And the biological interface risk is highlighted. Breakthroughs need to build a "power-control-interface" collaborative system: integrate isotope physics (develop new beta radiation sources), AI algorithms (dynamic power regulation) and synthetic biology (radiation-resistant biological coatings), which is expected to achieve safe and reliable long-term implantation. SUMMARY

[0009] The purpose of the present application is to solve the problems in the background art, and to provide a magnetic suspension heart pump system based on nuclear battery power supply and a control method thereof.

[0010] The technical scheme of the present application is a magnetic suspension heart pump system based on nuclear battery power supply, which comprises a nuclear battery power supply module, a magnetic suspension blood pump, a supercapacitor energy storage module, a wireless communication module and a control module.

[0011] The nuclear battery power supply module uses nickel-63 as fuel, adopts a diamond packaging and a modular sandwich structure, and supplies power for the magnetic suspension blood pump.

[0012] The supercapacitor energy storage module is used for short-time release of peak power, and assists the power supply for the magnetic suspension blood pump.

[0013] The control module dynamically adjusts the blood pump operating parameters based on machine learning algorithms.

[0014] The magnetic suspension heart pump system is connected with an external terminal through the wireless communication module, and all implanted components are connected without transcutaneous lead, without the need for external cable to penetrate the skin.

[0015] Further, the nuclear battery power supply module specifically comprises: a single crystal diamond substrate, whose crystal face is etched by plasma to form a periodic microcolumn array.

[0016] A nickel-63 fuel layer is deposited on the substrate, and a nano-island structure is formed by a magnetron sputtering process.

[0017] a top diamond encapsulation layer, a carbon-12 isotope diamond film is grown by a microwave plasma chemical vapor deposition process, and a crystal face of the carbon-12 isotope diamond film is parallel to a surface of the substrate;

[0018] a charge collection enhancement structure, a periodic graphene interlayer is embedded at an interface between the substrate and the encapsulation layer.

[0019] Further, the units are bonded through a diamond-metal interface, stacked into a modular sandwich structure, a stacking layer spacing is controlled to be 5 μm-20 μm, and a zigzag electric field distribution structure is adopted.

[0020] Further, an outer layer of the modular sandwich structure is covered with a protective shell, the protective shell is made of a biocompatible material, and is specifically selected from aluminum nitride ceramic or titanium alloy; and a silicon rubber buffer layer is filled between the protective shell and the internal module.

[0021] Further, a pump cavity of the magnetic levitation blood pump is formed by a selective sintering technology 3D printing, and is made of a medical grade polyurethane or silicon rubber material; an impeller of the magnetic levitation blood pump is designed in a centrifugal type, and a surface of the impeller is coated with a phosphatidylcholine group biomimetic coating, a covalent bond heparin coating and a polysulfobetaine zwitterionic polymer coating in sequence.

[0022] Further, a driving system of the magnetic levitation blood pump includes a stator coil and a Hall sensor, a rotating magnetic field is generated by closed-loop feedback control to maintain the impeller levitation stable, the stator coil adopts a medical grade polyether ether ketone or polytetrafluoroethylene as a biocompatible insulation packaging material, or adopts a composite packaging structure formed by a polydopamine biomimetic coating and a chitosan-based composite material.

[0023] Further, a peak power output of the supercapacitor energy storage module is not less than 20 watts, and is used to supplement a basic power output of the nuclear battery when a flow of the blood pump suddenly changes.

[0024] Further, a total power output of the nuclear battery energy supply module is 1 watt-2 watts, and the supercapacitor energy storage module is used to realize a hybrid energy supply mode.

[0025] Further, the control module includes an embedded microprocessor and an adaptive control algorithm of a decision model.

[0026] Real-time collection of cardiac output, blood pressure, blood oxygen saturation and impeller position data, dynamic adjustment of pump speed through a deep reinforcement learning model, and precise matching with physiological needs of a patient are realized.

[0027] The control module is configured with a thrombosis risk prediction module, a time sequence convolutional neural network model, historical physiological data and real-time hemodynamic parameters are fused, key features are extracted through an attention mechanism, thrombosis probability is predicted, and multi-level warning signals are sent to a medical terminal.

[0028] A control method of a magnetic suspension heart pump based on a nuclear battery power supply controls the system, and comprises the following specific steps:

[0029] S1: multi-modal physiological signal acquisition and preprocessing

[0030] Real-time acquisition of the patient's cardiac output, arterial blood pressure, blood oxygen saturation, impeller speed and pump cavity shear stress signals; the original signals are filtered, normalized and feature extracted by an embedded microprocessor to generate a standardized physiological data set.

[0031] S2: dynamic pump speed regulation and energy distribution

[0032] The standardized physiological data set is input into a deep reinforcement learning (DRL) model, the DRL model is pre-trained for 500,000 steps based on a PPO algorithm, and the target pump speed adjustment amount is output; if the cardiac output demand increases, the pump speed is increased according to a predetermined program; if the blood oxygen saturation decreases (Delta SpO2 is less than or equal to 3%), an emergency mode is triggered, the pump speed is instantaneously increased to 4000 rpm, and the super capacitor energy storage module is activated to supplement energy; the impeller speed of the magnetic suspension blood pump is adjusted according to different physiological conditions, so that it is continuously adjusted within the range of 1800 rpm to 4000 rpm.

[0033] S3: thrombosis risk prediction and active warning

[0034] Real-time hemodynamic parameters (including pump cavity pressure, blood flow velocity, D-dimer concentration) are input into a time sequence convolutional neural network (TCN) model; the TCN model comprises 4 layers of dilated convolution and a multi-head attention mechanism, and outputs a thrombosis probability (P_thrombus); if P_thrombus is greater than or equal to 0.7, a three-level warning signal (low / medium / high risk) is sent to a medical terminal through a wireless communication module, and the pump speed is automatically adjusted to reduce the shear stress.

[0035] S4: wireless communication and remote collaborative control

[0036] The pump speed, energy state and warning information are transmitted to an external terminal through Bluetooth / Wi-Fi protocol; remote instruction is received to update the DRL model parameters or switch the control mode (such as sleep mode: fixed pump speed 1800 rpm; exercise mode: adaptive dynamic adjustment).

[0037] Compared with the prior art, the present application has the following beneficial technical effects:

[0038] By the innovative nuclear power-capacitor hybrid power supply system, the nickel-63 nuclear battery provides lifelong basic power supply (1-2 watts), combined with the super capacitor short-time release of not less than 20 watts of peak power, to realize the precise balance of energy density and dynamic demand, the overall endurance life of the system breaks through 50 years, and the pain points of traditional artificial heart relying on external power supply and frequent battery replacement are completely solved; the AI-driven adaptive control system deeply integrates machine learning algorithm and multi-modal physiological perception technology, collects cardiac output, blood oxygen and impeller state data in real time, dynamically optimizes pump speed and flow distribution, not only reduces the average energy consumption, but also accurately matches the physiological state changes such as patient exercise and sleep, and at the same time, through neural network prediction of thrombus risk and active warning, the treatment safety is greatly improved; in addition, the whole system adopts a leadless fully implanted design, realizes parameter calibration, remote upgrade and fault diagnosis through a wireless communication module, completely eliminates the risk of infection caused by percutaneous lead (traditional VAD infection rate 10%-20%), combined with 3D printing customized pump cavity and anticoagulant coating, significantly reduces the incidence of thrombosis and complications, and provides a safe, long-acting and intelligent treatment option for patients with end-stage heart failure. BRIEF DESCRIPTION OF DRAWINGS

[0039] Figure 1 It is a schematic diagram of the overall structure of the system according to the embodiment of the application.

[0040] Figure 2 It is a schematic diagram of the sandwich packaging structure of the nuclear battery module.

[0041] Figure 3 It is a periodic graphene interlayer.

[0042] Figure 4 It is a diamond substrate crystal face diagram.

[0043] Figure 5 It is a blood pump structure diagram.

[0044] Figure 6 It is a control flowchart of the control system.

[0045] Reference signs: 1, nuclear battery power supply module; 2, super capacitor energy storage module; 3, control module; 4, magnetic suspension blood pump; 5, wireless communication module; 6, protective layer; 7, upper electrode; 8, diamond semiconductor layer; 9, radioactive source layer; 10, lower electrode; 11, graphene interlayer; 12, periodic microcolumn array; 13, diamond substrate. DETAILED DESCRIPTION

[0046] Example 1

[0047] The nuclear battery-powered magnetic levitation heart pump system of the application comprises a magnetic levitation blood pump 4, a nuclear battery power supply module 1, a super capacitor energy storage module 2 and a control module 3. The magnetic levitation blood pump 4 drives a centrifugal impeller through a magnetic levitation bearing, and the surface of the impeller is coated with an anticoagulant coating, and the inner wall of the blood pump flow passage is polished to reduce the blood flow resistance, both of which cooperate to realize non-contact blood driving; the nuclear battery power supply module 1 is composed of a single crystal diamond substrate 13, a nickel-63 fuel layer and a top diamond packaging layer, each power generation unit is independently packaged and stacked into a modular sandwich structure, which cooperates with the super capacitor energy storage module 2 to form a dual-mode energy network; the adaptive intelligent control algorithm based on the DeepSeek-R1 framework and the OpenAI GPT-4o generative decision model of the control module 3 collects physiological data in real time and dynamically adjusts the pump speed, and dynamically adjusts the pump speed through the deep reinforcement learning (DRL) model to ensure that the blood flow dynamics and patient demand are accurately matched.

[0048] The nuclear battery power supply module 1 uses nickel-63 as fuel and adopts diamond packaging technology, and is composed of a single crystal diamond substrate 13, a radioactive source layer 9 and a top diamond packaging layer to form an independent power generation unit. Each unit is stacked into a modular sandwich structure, and the outer layer is covered with a protective layer 6 formed by a biocompatible aluminum nitride ceramic or titanium alloy protective shell. The total power output is 1-2 watts. The single crystal diamond substrate 13 has a crystal surface that is plasma etched to form a periodic microcolumn array 12. The working principle is as follows: the beta particles (maximum energy 66.9keV) released by the decay of nickel-63 penetrate the fuel layer and ionize to form electron-hole pairs in the diamond layer. The built-in electric field separates to form an electric current. The open-circuit voltage of a single power generation unit is 0.85V, and the energy conversion efficiency is ≥15%.

[0049] Each unit in the nuclear battery power supply module 1 is stacked into a modular sandwich structure (interlayer spacing 5-20μm) through diamond-metal (Ti / Pt / Au) bonding, as shown in Figure 2 From top to bottom, the sandwich structure is protective layer 6, upper electrode 7, diamond semiconductor layer 8, radioactive source layer 9, lower electrode 10 and graphene interlayer 11. Combined with the sawtooth-shaped electric field distribution design, the beta particle penetration rate is <0.1%, and the overall radiation dose rate is <0.05μSv / h, which meets the safety standards and ensures long-term implantation safety. This design realizes high-efficiency energy conversion and miniaturized integration through nanostructure optimization, diamond packaging and graphene enhancement technology, breaking through the power density and radiation safety bottleneck of traditional nuclear batteries. The modular sandwich structure solves the problem of large size (size ≤50×50×30mm 3);diamond package, single crystal substrate + top package layer, effectively reduce the radiation leakage rate; through the nickel-63 decay can continue to power more than 50 years, the realization of intelligent nuclear power heart pump system total power in 1 watt-2 watts, without replacing the battery.

[0050] The magnetic levitation blood pump 4 includes a centrifugal impeller, a magnetic levitation driving unit, and a 3D printed pump cavity. The impeller rotation speed range is 1800-4000 rpm, and the surface is coated with a heparin-polydopamine composite coating, an anticoagulant coating. The magnetic levitation driving unit adopts closed-loop control, controls the dielectric strength of the stator coil packaging material, and maintains the impeller in suspension and stability through closed-loop feedback electromagnetic force. The stator coil adopts biocompatible insulating material medical grade polyether ether ketone (PEEK) or polytetrafluoroethylene (PTFE), or a composite packaging structure formed by polydopamine biomimetic coating and chitosan-based composite material as packaging; the pump cavity flow channel is designed by fluid mechanics optimization, and is formed by selective laser sintering (SLS) technology 3D printing, the material is medical grade polyurethane or silicone rubber, SLS forming medical polyurethane pump cavity, the flow channel turbulence intensity is reduced to below 5%, much smaller than traditional pump cavity.

[0051] The supercapacitor energy storage module 2 has a peak power output of not less than 20 watts, which is used to supplement the basic power of the nuclear battery when the blood pump flow suddenly changes, to ensure the dynamic balance of energy density and power output. The supercapacitor energy storage module 2 used can dynamically balance the power of the nuclear battery through the instantaneous energy of the capacitor in motion, stress, etc., while the nuclear battery provides a basic power of 1-2 watts.

[0052] The control module 3 in the nuclear power heart pump includes an embedded microprocessor and a lightweight AI model, which collects cardiac output, blood pressure, blood oxygen saturation, and impeller position data in real time, dynamically adjusts the pump speed through machine learning algorithm, and learns the algorithm based on DRL dynamic regulation. Based on the DeepSeek-R1 framework and the adaptive intelligent control algorithm of the OpenAI GPT-4o generated decision model, the pump speed control error is less than 5%; at the same time, the thrombus risk prediction module-TCN thrombus prediction is configured, which fuses 17-dimensional real-time data (historical physiological data, real-time hemodynamic parameters, shear stress, D-dimer, and coagulation factor concentration) based on neural network model through attention mechanism to extract key features, predict thrombus formation probability, and send warning signal to medical terminal.

[0053] The design scheme of the artificial heart pump dynamic regulation system and the thrombus prediction module based on deep reinforcement learning (DRL) is as follows. The DRL algorithm constructs a state space through 12-dimensional real-time physiological and device parameters (such as cardiac output, blood oxygen saturation, impeller speed, etc.), adopts the PPO algorithm for 500,000-step offline pre-training, and combines federated learning to update the model every week, outputs the impeller speed adjustment (discrete three gears or continuous adjustment), and optimizes the control under the constraints of energy efficiency ratio ≥80% and turbulent intensity ≤5%; the thrombus risk prediction adopts a TCN model, inputs 17-dimensional time series data (including blood flow velocity, D-dimer concentration, etc.), calculates the probability through 4 layers of dilated convolution and multi-head attention mechanism, triggers an early warning when the threshold is 0.7, and realizes <50ms real-time inference on an FPGA accelerator. In actual application, the basic speed is set to 1800 rpm, adjusted linearly according to the cardiac output, and the patient's safety is ensured through safety thresholds (such as blood oxygen <90% for 10 seconds to enter emergency mode).

[0054] The nuclear battery powered magnetic suspension heart pump system needs to adopt a leadless implant design, all components are connected with the external terminal through the wireless communication module 5, supports postoperative parameter calibration, remote software upgrade and fault diagnosis, through wireless communication and leadless design to make the infection risk zero, completely eliminate the risk of percutaneous lead infection.

[0055] A specific case is provided below to introduce the scheme of the application in detail.

[0056] As shown in Figures 1-3 The nuclear power heart pump and its intelligent system of the application include a magnetic suspension blood pump 4, a nuclear battery power supply module 1, a super capacitor energy storage module 2, a control module 3 and a wireless communication module 5. Each component cooperates to realize lifelong power supply, dynamic power regulation and intelligent blood driving.

[0057] In the example of the application, the nuclear battery power supply module 1 uses nickel-63 as fuel, adopts diamond packaging technology Figure 2 As shown in the figure), the nuclear battery adopts a multi-layer diamond composite packaging technology, including a single crystal diamond substrate 13, a nickel-63 fuel layer and a diamond packaging layer to form an independent power generation unit, each unit is stacked into a modular sandwich structure (interlayer spacing 5-20 μm) through diamond-metal (Ti / Pt / Au) bonding, and the outer layer is covered with an aluminum nitride ceramic or titanium alloy protective shell to shield radiation, which can provide 1-2 watts of basic power.

[0058] The working principle is that the beta particles (maximum energy 66.9 keV) released by nickel-63 decay penetrate the fuel layer and ionize to generate electron-hole pairs in the diamond layer, and the current is formed by the separation of the built-in electric field. The open-circuit voltage of the single-layer unit is 0.85 V, and the energy conversion efficiency is greater than or equal to 15%; combined with the design of the sawtooth-shaped electric field distribution, the beta particle penetration rate is less than 0.1%, and the radiation dose rate is less than 0.05 μSv / h, which meets the safety standards and realizes efficient miniaturization power supply and lifelong safe implantation.

[0059] In the examples of the present application, the supercapacitor energy storage module 2 is connected in parallel with the nuclear battery, and the peak power output is not less than 20 watts, which is used to instantaneously supplement the power gap when the blood pump flow suddenly changes (such as when the patient is moving), and realizes the precise balance of energy density and dynamic demand. The dual-mode power supply system makes the overall endurance life of the system break through 50 years, and completely gets rid of the dependence on external power supply of traditional VAD.

[0060] In the examples of the present application, the control module 3 runs a lightweight machine learning model based on an embedded microprocessor, and collects cardiac output, blood pressure, blood oxygen saturation and impeller position data in real time, and dynamically optimizes the pump speed and flow distribution through an algorithm. For example, when the patient is moving, the pump speed is automatically increased to 4000 rpm, and when sleeping, the pump speed is reduced to 1800 rpm, which accurately matches the physiological demand. At the same time, the system integrates a thrombosis risk prediction module, which analyzes historical and real-time data (such as blood flow velocity and pump cavity pressure) based on the DeepSeek-R1 framework and the adaptive intelligent control algorithm of the time convolutional neural network (TCN) model generated by the OpenAI GPT-4o generative decision model, predicts the risk of thrombosis, and sends an early warning signal to the medical terminal through the wireless communication module 5, to realize active safety protection.

[0061] In the examples of the present application, the magnetic suspension blood pump 4 realizes non-contact blood driving through a centrifugal impeller (rotating speed 1800-4000 rpm). The impeller surface is coated with an anticoagulant coating (such as a phosphocholine group biomimetic coating, a covalent bond heparin coating and a polysulfobetaine zwitterionic polymer coating), combined with a 3D printed pump cavity (material is medical grade polyurethane or silicone rubber) optimized by fluid mechanics, which significantly reduces the risk of turbulence and thrombosis. The magnetic suspension driving unit is composed of a stator coil and a Hall sensor, which generates a rotating magnetic field through closed-loop feedback control to maintain the stability of the impeller suspension. The pump cavity is implanted between the left ventricle and the aorta through minimally invasive surgery, and directly participates in physiological level blood circulation support.

[0062] In the examples of the present application, all implanted components of the system (blood pump, nuclear battery, super capacitor, control module 3) are connected without percutaneous wires, and are encapsulated by biocompatible materials. The wireless communication module 5 supports Bluetooth / Wi-Fi protocols, and realizes postoperative parameter calibration (such as initial pump speed setting), remote software upgrade (optimizing AI algorithms), and real-time fault diagnosis (such as nuclear battery output anomaly alarm), completely eliminating the risk of infection caused by traditional VAD wires (reducing the incidence to 0%).

[0063] Taking an actual use scenario as an example: when the patient climbs a mountain, the cardiac output demand suddenly increases, through physiological sensing, the control module 3 will decrease the blood oxygen saturation, and the cardiac output demand will increase from 5 L / min to 12 L / min; the super capacitor releases power instantaneously, and the pump speed is rapidly increased in a short time; the 3D printing flow channel controls the turbulence intensity to avoid the risk of hemolysis; the TCN model predicts shear stress abnormalities, triggers a first-level warning and adjusts the pump speed; finally, according to the real-time data, the encrypted transmission is carried out to the patient's smart watch and the hospital monitoring platform.

[0064] Those skilled in the art can understand that the above only describes the preferred embodiments of the present application, and is not used to limit the present application, although the present application has been described in detail with reference to the foregoing embodiments, and for those skilled in the art, the technical solutions recorded in the foregoing embodiments can be modified, or some technical features can be replaced. Any modification, equivalent replacement, improvement, etc. within the spirit and principles of the present application shall be included in the protection scope of the present application.

[0065] The embodiments of the present application are described in detail above in combination with the drawings, but the present application is not limited thereto, and various changes can be made within the knowledge of those skilled in the art without departing from the purpose of the present application.

Claims

1. A magnetic levitation heart pump system powered based on a nuclear battery, characterized in that, The nuclear battery power supply module, the magnetic levitation blood pump, the super capacitor energy storage module, the wireless communication module and the control module are included. The nuclear battery power supply module uses nickel-63 as fuel, adopts a diamond packaging and a modular sandwich structure, and supplies power for the magnetic levitation blood pump. The nuclear battery power supply module specifically includes: a single crystal diamond substrate, the crystal surface of which is etched by plasma to form a periodic micro column array. A nickel-63 fuel layer is deposited on the substrate, and a nano-island structure is formed by a magnetron sputtering process. A top diamond packaging layer, a carbon-12 isotope diamond film is grown by a microwave plasma chemical vapor deposition process, and the crystal surface is parallel to the substrate surface. A charge collection enhancement structure is embedded with a periodic graphene interlayer at the interface between the substrate and the packaging layer. The super capacitor energy storage module is used for short-time release of peak power to assist the power supply of the magnetic levitation blood pump. The control module dynamically adjusts the blood pump operating parameters based on a machine learning algorithm. The magnetic levitation heart pump system is connected with an external terminal through a wireless communication module, and all implanted components are connected without a percutaneous lead, without the need for external cable penetration through the skin.

2. The nuclear battery powered magnetic levitation heart pump system of claim 1, wherein, Each unit is bonded through a diamond-metal interface and stacked into a modular sandwich structure, and the spacing between the stacked layers is controlled at 5-20 μm.

3. The nuclear battery powered magnetic levitation heart pump system according to claim 1 or 2, characterized in that The outer layer of the modular sandwich structure is covered with a protective shell made of biocompatible material, specifically selected from aluminum nitride ceramic or titanium alloy; the protective shell and the internal module are filled with a silicone rubber buffer layer.

4. The nuclear battery-based powered magnetic levitation heart pump system of claim 1, wherein, The pump cavity of the magnetic levitation blood pump is formed by 3D printing by selective sintering technology, and is made of medical grade polyurethane or silicone rubber material; the impeller of the magnetic levitation blood pump adopts a centrifugal design, and the surface of the impeller is coated with a phosphatidylcholine group biomimetic coating, a covalent bond heparin coating and a polysulfobetaine zwitterionic polymer coating in turn.

5. The nuclear battery powered magnetic levitation heart pump system of claim 4, wherein, The driving system of the magnetic levitation blood pump includes a stator coil and a Hall sensor, which generates a rotating magnetic field through closed-loop feedback control to maintain the suspension stability of the impeller, and the stator coil uses medical grade polyether ether ketone or polytetrafluoroethylene as a biocompatible insulation packaging material, or uses a composite packaging structure formed by a polydopamine biomimetic coating and a chitosan-based composite material.

6. The nuclear battery-based powered magnetic levitation heart pump system of claim 1, wherein, The peak power output of the super capacitor energy storage module is not less than 20 watts, which is used to supplement the basic power output of the nuclear battery when the blood pump flow suddenly changes.

7. The nuclear battery-based powered magnetic levitation heart pump system of claim 1, wherein, The total power output of the nuclear battery power supply module is 1-2 watts, which cooperates with the super capacitor energy storage module to realize a hybrid power supply mode.

8. The nuclear battery-based powered magnetic levitation heart pump system of claim 1, wherein, The control module includes an embedded microprocessor and an adaptive control algorithm of a decision model; Real-time acquisition of cardiac output, blood pressure, blood oxygen saturation and impeller position data, dynamic adjustment of pump speed through a deep reinforcement learning model, and precise matching with the physiological needs of the patient are realized. The control module is configured with a thrombosis risk prediction module and a time series convolutional neural network model, which integrates historical physiological data and real-time hemodynamic parameters, extracts key features through an attention mechanism, predicts the probability of thrombosis, and sends multi-level warning signals to a medical terminal.

9. The nuclear battery-based powered magnetic levitation heart pump system of claim 1, wherein, The system controls operation according to the following steps: S1: Multimodal physiological signal acquisition and preprocessing Real-time acquisition of patient's cardiac output, arterial blood pressure, oxygen saturation, impeller speed and pump cavity shear stress signals; through embedded microprocessor to filter, normalize and feature extraction of the original signal, generate standardized physiological data set; S2: Dynamic pump speed control and energy distribution Input the standardized physiological data set into the deep reinforcement learning model, the deep reinforcement learning DRL model is pre-trained for 500,000 steps based on PPO algorithm, and the output is the target pump speed adjustment; If the cardiac output demand increases, increase the pump speed according to the predetermined program; if the oxygen saturation decreases, trigger the emergency mode, instantaneously increase the pump speed to 4000 rpm, and activate the super capacitor energy storage module to supplement energy; adjust the impeller speed of the magnetic suspension blood pump according to different physiological conditions, so that it is continuously adjusted within the range of 1800 rpm to 4000 rpm; S3: Thrombus risk prediction and active warning Input the real-time hemodynamic parameters into the time series convolutional neural network TCN model; the TCN model contains 4 layers of dilated convolution and multi-head attention mechanism, and outputs the thrombus formation probability P_thrombus; if P_thrombus ≥ 0.7, send a three-level warning signal to the medical terminal through the wireless communication module, and automatically adjust the pump speed to reduce the shear stress; S4: Wireless communication and remote collaborative control Through Bluetooth / Wi-Fi protocol, the pump speed, energy state and warning information are transmitted to the external terminal; receive remote instruction to update DRL model parameters or switch control mode.

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