Multifunctional constant-temperature mixing instrument for molecular diagnosis of clinical laboratory

Abstract

The invention relates to the technical field of medical apparatus and instruments, in particular to a multifunctional constant-temperature mixing instrument for molecular diagnosis in a clinical laboratory, which comprises a constant-temperature box, a liquid storage box is fixedly mounted at the inner end of the constant-temperature box, an isolating ring is arranged above the liquid storage box and fixedly connected with the constant-temperature box, and a grid plate is fixedly clamped at the inner end of the isolating ring. A plurality of holes are formed in the outer surface of the grid plate, test tubes are arranged in the holes in a penetrating mode, a swinging device is arranged below the grid plate and used for driving the test tubes to swing, a central tube is fixedly installed at the bottom end of the inner side of the constant-temperature box and located below the liquid storage box, and a stirring device is arranged between the liquid storage box and the central tube. The stirring device is arranged in the liquid storage tank and used for stirring liquid in the liquid storage tank, the test tube is driven to shake through undulation of water, reagents in the test tube can be uniformly mixed, the problem of non-uniformity caused by single mixing direction possibly occurring in a traditional uniform mixing mode is avoided, and the accuracy and reliability of experiments are improved.

Description

Technical Field

[0001] The invention relates to the technical field of medical instruments, in particular to a multifunctional constant temperature mixer for molecular diagnosis in a laboratory. Background Art

[0002] The constant temperature mixer uses a brushless DC motor and microprocessor technology combined with intelligent PID. It can quickly maintain stability after reaching the target temperature, saving waiting time and perfectly combining the two functions of constant temperature and oscillation, greatly shortening the experimental operation time and improving the efficiency of the staff. It is an ideal automation tool for sample incubation, catalysis, mixing and storage reaction processes. The constant temperature mixer has multi-purpose functions such as heating and oscillation.

[0003] After searching, it was found that the prior art publication number is CN218422384U, which discloses a constant temperature mixer. The constant temperature mixer includes: a chassis; a constant temperature seat, embedded in the top of the chassis; a reagent bottle, used to contain a solution; a carrying bottle, arranged on the constant temperature seat, the carrying bottle includes a containing part, a guide part and an overflow part connected in sequence from bottom to top, the containing part is adapted to the size of the reagent bottle and is used to contain the reagent bottle, the inner height of the containing part is equal to the height of the reagent bottle, the inner diameter of the overflow part is larger than the inner diameter of the containing part, and the guide part can drain the liquid in the overflow part to the reagent bottle located in the containing part. This solution can prevent the liquid in the reagent bottle from overflowing during the oscillation and mixing of the constant temperature mixer.

[0004] Therefore, based on the above search and in combination with existing technologies, when multiple test tubes are mixed together, there is a problem of uneven temperature distribution due to the limitations of the mixing device. The existing technology makes it difficult to ensure the consistency of the temperature of each test tube. The temperature of some test tubes may be too high or too low, and it is difficult to maintain a constant temperature for each test tube, resulting in the inability to flexibly meet diverse experimental needs. For this reason, we propose a multifunctional constant temperature mixer for molecular diagnosis in the laboratory. Summary of the invention

[0005] The purpose of the present invention is to provide a multifunctional constant temperature mixer for molecular diagnosis in laboratory to solve the problems raised in the above background technology.

[0006] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a multifunctional constant temperature mixer for molecular diagnosis in a laboratory, comprising a constant temperature box, a liquid storage tank is fixedly installed at the inner end of the constant temperature box, an isolation ring is arranged above the liquid storage tank, and the isolation ring is fixedly connected to the constant temperature box, a grid plate is fixedly clamped at the inner end of the isolation ring, and a plurality of holes are opened on the outer surface of the grid plate, test tubes are passed through the holes, a swing device is arranged below the grid plate for driving the test tube to swing, the liquid storage tank is filled with water, a heating tube is arranged inside the constant temperature box for heating the water in the liquid storage tank, and constant temperature control of the test tube is achieved through heat transfer of the water, a central tube is fixedly installed at the inner bottom end of the constant temperature box, the central tube is located below the liquid storage tank, a stirring device is arranged between the liquid storage tank and the central tube for stirring the liquid inside the liquid storage tank.

[0007] As a further solution of the present invention, the swing device includes an inner sleeve, a plurality of movable rings are arranged inside the inner sleeve, and the movable rings correspond to the holes on the outer surface of the grid plate. The movable rings are grouped in a horizontal arrangement, and two adjacent movable rings are rotationally connected by a connecting shaft.

[0008] As a further solution of the present invention, a movable sleeve is rotatably installed on the inner end of the movable ring, and the rotation direction of the movable sleeve is vertically staggered with the rotation direction of two adjacent movable rings. The test tube is inserted into the interior of the movable sleeve, and the staggered rotation of the movable ring and the movable sleeve can achieve the effect of the test tube being able to rotate in any direction inside the liquid storage tank.

[0009] As a further solution of the present invention, the bottom end of the movable sleeve is rotatably connected to a plurality of clamping plates via a rotating shaft, the plurality of clamping plates are arranged in a ring shape, and the outer surfaces of the clamping plates are fixedly connected with plate blades, the clamping plates and the movable sleeve are clamped by a torsion spring, the inner end fixed sleeve of the movable sleeve is provided with a wiper ring, the wiper ring contacts the outer surface of the test tube, and the plurality of clamping plates rotatably connected via a rotating shaft are arranged in a ring shape, which can firmly clamp the test tube to prevent the test tube from falling off or shifting during the mixing process.

[0010] As a further solution of the present invention, the stirring device includes four expansion bags, which are respectively located at four corners inside the liquid storage tank. When the expansion bags are expanded, the water surface inside the liquid storage tank begins to fluctuate. A plurality of power storage cylinders are fixedly installed at the bottom end of the liquid storage tank, and the power storage cylinders correspond to the expansion bags. The power storage cylinders and the expansion bags are connected through an air duct.

[0011] As a further solution of the present invention, an air pipe is provided inside the power storage cylinder, the output end of the central pipe is connected to the air pipe via an output pipe, a sealing plate is fixedly sleeved on the outer surface of the air pipe, and a piston is sleeved on the outer surface of the air pipe. By arranging the air pipe inside the power storage cylinder and combining the design of the sealing plate and the piston, this structure not only realizes efficient and stable transmission of gas, but also improves the sealing performance and control flexibility of the system, and has significant advantages such as compact structure, high reliability, and easy maintenance.

[0012] As a further solution of the present invention, the piston and the sealing plate are connected by a return spring, a ventilation block is penetrated inside the air duct, and a plurality of ventilation grooves are opened on the outer surface of the ventilation block. After the ventilation block moves to the right, the ventilation grooves are exposed inside the power storage cylinder, and the piston and the sealing plate are connected by a return spring, so that the piston can automatically reset after completing the action, thereby improving the automation degree and operation efficiency of the system.

[0013] As a further solution of the present invention, an end of the ventilation block close to the piston is fixedly connected to an extrusion ring, the air supply pipe corresponds to the extrusion ring, and an end of the air supply pipe close to the extrusion ring is fixedly installed with a limiting ring for limiting the movable space of the piston, and the piston and the extrusion ring are connected by a traction line.

[0014] As a further solution of the present invention, a stabilizing plate is fixedly installed on the inner bottom end of the central tube, a driving shaft is arranged below the stabilizing plate, the driving shaft is rotatably connected to the inner bottom end of the constant temperature box, a driving motor is fixedly installed on the inner bottom end of the constant temperature box, the output shaft of the driving motor is fixedly connected to a crown gear, a passive gear is fixedly sleeved on the outer surface of the driving shaft, and the passive gear is meshed with the crown gear.

[0015] As a further solution of the present invention, a limit plate is fixedly installed on the inner end of the central tube, the limit plate is located above the stabilizing plate, and a movable shaft is passed through the center of the limit plate, the outer surface of the movable shaft is sleeved with a sealing plug, the bottom end of the movable shaft is fixedly connected with a corrugated sleeve, and the corrugated sleeve and the limit plate are connected by a trigger spring, two driving wheels are rotatably installed on the upper end of the driving shaft, and the driving wheels are located at the trough of the corrugated sleeve, and a switch plate is fixedly installed on the outer surface of the movable shaft, and the switch plate is located below the sealing plug.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] 1. When the present invention is used, the test tube is shaken by the undulation of water, so that the reagents inside the test tube can be evenly mixed, avoiding the problem of uneven mixing due to a single mixing direction that may occur in the traditional mixing method, thereby improving the accuracy and reliability of the experiment;

[0018] 2. When the present invention is used, during the mixing process, by heating the water, the reagent in the test tube can be kept at a constant temperature, thereby avoiding experimental errors caused by temperature fluctuations. The present invention is suitable for molecular diagnostic experiments that are sensitive to temperature. The heating of the water not only provides a heat preservation effect, but also can adjust the temperature according to the experimental requirements, thereby ensuring that the reagent reacts under the optimal temperature conditions, thereby improving the success rate and efficiency of the experiment.

[0019] 3. The present invention uses the fluctuation of water to drive the test tube to shake, which reduces the use of mechanical parts, reduces the wear and failure rate of the equipment, and prolongs the service life of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 This is a schematic diagram of the structure of a multifunctional constant temperature mixer for molecular diagnosis in laboratory;

[0021] Figure 2 This is a disassembled diagram of the interior of the thermostat;

[0022] Figure 3 is a schematic diagram of the structure of the swing device;

[0023] Figure 4 It is a schematic diagram of the structure inside the movable sleeve;

[0024] Figure 5 is a schematic diagram of the structure of the stirring device;

[0025] Figure 6 It is a schematic diagram of the structure inside the power storage cylinder;

[0026] Figure 7 It is a position relationship diagram between the gas transmission pipe and the partition sleeve;

[0027] Figure 8 Schematic diagram of the structure inside the central tube;

[0028] Fig. 9 This is a diagram showing the position relationship between the driving wheel and the corrugated sleeve.

[0029] In the figure: 1. Constant temperature box; 2. Test tube; 3. Insulation cover; 4. Isolation ring;

[0030] 101, grid plate; 102, movable sleeve; 103, inner sleeve; 104, clamping plate; 105, movable ring; 106, connecting shaft; 107, extrusion block; 108, passive rod; 109, wiper ring;

[0031] 201, liquid storage tank; 202, expansion bag; 203, power storage cylinder; 204, drive motor; 205, center tube; 206, air guide tube;

[0032] 301, ventilation block; 302, extrusion ring; 303, air pipe; 304, synchronization rod; 305, partition sleeve; 306, output pipe; 307, return spring; 308, piston; 309, traction line; 310, sealing plate; 311, partition block;

[0033] 401, crown gear; 402, driving shaft; 403, passive gear; 404, trigger spring; 405, movable shaft; 406, sealing plug; 407, limit plate; 408, stabilizing plate; 409, driving wheel; 410, corrugated sleeve; 411, on-off plate. DETAILED DESCRIPTION

[0034] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0035] Example 1: Please refer to Figure 1 - Figure 4 A multifunctional constant temperature mixer for molecular diagnosis in a laboratory comprises a constant temperature box 1, a liquid storage tank 201 is fixedly installed at the inner end of the constant temperature box 1, an isolation ring 4 is arranged above the liquid storage tank 201, and the isolation ring 4 is fixedly connected to the constant temperature box 1 by bolts, and a grid plate 101 is fixedly connected to the inner end of the isolation ring 4 by a buckle, and a plurality of holes are opened on the outer surface of the grid plate 101, and test tubes 2 are inserted into the holes, and a swing device is arranged below the grid plate 101 for driving the test tube 2 to swing, the liquid storage tank 201 is filled with water, and a heating pipe is arranged in the constant temperature box 1 for heating the water in the liquid storage tank 201, and the constant temperature control of the test tube 2 is realized through the heat transfer of the water;

[0036] A control terminal is provided at the left end of the thermostat 1, which is used to control the operation of the internal device of the thermostat 1. The liquid storage tank 201 is made of metal and has good thermal conductivity. A temperature sensor is installed inside it. The temperature sensor is connected to the control terminal through a wire, so that the control terminal can monitor the temperature of the liquid inside the liquid storage tank 201 in real time. The control terminal is an existing mature technology, and its specific working principle is not repeated here. An ultraviolet lamp is installed at the bottom end of the isolation ring 4. Through the irradiation of the ultraviolet lamp, the inside of the liquid storage tank 201 and the test tube 2 are disinfected in real time. A heat preservation cover 3 is provided above the thermostat 1, which is covered on the top of the thermostat 1 to achieve a warming effect;

[0037] A central tube 205 is fixedly installed at the inner bottom end of the thermostatic box 1 , and the central tube 205 is located below the liquid storage tank 201 . Specifically, a stirring device is provided between the liquid storage tank 201 and the central tube 205 for stirring the liquid inside the liquid storage tank 201 .

[0038] like Figure 3 , Figure 4 As shown, the swing device includes an inner sleeve 103, a plurality of movable rings 105 are arranged inside the inner sleeve 103, and the movable rings 105 correspond to the holes on the outer surface of the grid plate 101, and the movable rings 105 are arranged in groups in a transverse manner, and two adjacent movable rings 105 are rotatably connected by a connecting shaft 106, and the movable ring 105 close to the inner sleeve 103 is also rotatably connected to the inner sleeve 103 by the connecting shaft 106, and the inner end of the movable ring 105 is rotatably mounted with a movable sleeve 102 through a rotating shaft, and the rotation direction of the movable sleeve 102 is vertically staggered with the rotation direction of the two adjacent movable rings 105, and the test tube 2 is inserted into the movable sleeve 102, and the staggered rotation of the movable ring 105 and the movable sleeve 102 realizes the effect that the test tube 2 can rotate in any direction inside the liquid storage tank 201;

[0039] The bottom end of the movable sleeve 102 is rotatably connected to a plurality of clamping plates 104 through a rotating shaft. The plurality of clamping plates 104 are arranged in a ring shape, and the outer surfaces of the clamping plates 104 are fixedly connected with plate blades. When the water flow inside the liquid storage tank 201 is agitated, the plate blades increase the contact area with the water. Under the action of the continuous agitation of the water flow, the test tube 2 is driven to shake through the movable sleeve 102, thereby achieving the shaking of the reagent inside. At the same time, under the blocking of the plate blades, the test tubes 2 can be prevented from colliding with each other. The clamping plate 104 and the movable sleeve 102 are connected by a torsion spring to increase the clamping force of the clamping plate 104 on the test tube 2 and make it more stable. The outer surface of the clamping plate 104 is covered with a rubber pad to avoid scratching the outer surface of the test tube 2. The inner end of the movable sleeve 102 is fixedly covered with a wiper ring 109, which contacts the outer surface of the test tube 2. When the test tube 2 is drawn out, the water on the test tube 2 passing through the liquid storage tank 201 will be scraped off by the wiper ring 109.

[0040] Specifically, a plurality of passive rods 108 are rotatably mounted on the outer surface of the movable sleeve 102. The passive rods 108 correspond to the clamping plate 104 and are located above the clamping plate 104. The bottom ends of the passive rods 108 are in contact with the outer surface of the clamping plate 104. A plurality of rectangular holes are provided on the outer surface of the movable sleeve 102. The rectangular holes correspond to the passive rods 108. The upper ends of the passive rods 108 are slidably connected with extrusion blocks 107. The extrusion blocks 107 are inserted into the rectangular holes. The extrusion blocks 107 and the passive rods 108 are connected by springs. When the test tube After being inserted into the movable sleeve 102, its outer surface contacts the clamping plate 104, causing the clamping plate 104 to rotate, and then the outer surface of the clamping plate 104 pushes the passive rod 108 to rotate, causing the extrusion block 107 to move toward the test tube 2 and contact the outer surface of the test tube 2. The outer surface of the extrusion block 107 is covered with a rubber pad to avoid scratching the test tube 2. The test tube 2 is clamped by the clamping plate 104 and the extrusion block 107, respectively, to achieve two-point fixation of the test tube 2, further preventing the test tube 2 from shaking inside the movable sleeve 102.

[0041] Example 2: Please refer to Figure 5 , Figure 6 , Figure 7 , a multifunctional constant temperature mixer for molecular diagnosis in a laboratory, which is different from Example 1 in that the stirring device includes four expansion capsules 202, which are respectively located at four corners inside a liquid storage tank 201, and the expansion capsules 202 are made of silicone rubber, and have good corrosion resistance, high temperature resistance, and fatigue resistance. When the expansion capsules 202 expand, the water surface inside the liquid storage tank 201 begins to fluctuate, and a plurality of power storage cylinders 203 are fixedly installed at the bottom end of the liquid storage tank 201 through a clamp, and the power storage cylinders 203 correspond to the expansion capsules 202, and the power storage cylinders 203 and the expansion capsules 202 are connected through an air guide tube 206. Specifically, the power storage cylinders 203 are located on the left and right sides of a central tube 205, and the input ends of two adjacent power storage cylinders 203 correspond to each other;

[0042] The inside of the power storage cylinder 203 is penetrated by an air pipe 303, and the output end of the central tube 205 is connected to the air pipe 303 through an output pipe 306, and the output pipe 306 is made of soft silicone rubber. The outer surface of the air pipe 303 is fixedly sleeved with a sealing plate 310, wherein the air pipe 303 on the left side is slidably connected to the sealing plate 310, and the air pipe 303 on the right side is fixedly connected to the sealing plate 310 on the right side. Specifically, the left air pipe 303 is connected to the sealing plate 310 through a sealing rubber ring. In order to increase the air tightness, a piston 308 is sleeved on the outer surface of the air delivery pipe 303, and a sealing rubber ring is sleeved on the outer surface of the piston 308, and it fits with the inner wall of the power storage cylinder 203 to achieve the effect of increasing the air tightness. The piston 308 is connected to the sealing plate 310 by a return spring 307. A ventilation block 301 is penetrated inside the air guide pipe 206, and a plurality of ventilation grooves are opened on the outer surface of the ventilation block 301, and the ventilation grooves are arranged in a ring shape. After the ventilation block 301 moves to the right, the ventilation grooves are exposed inside the power storage cylinder 203.

[0043] The end of the vent block 301 close to the piston 308 is fixedly connected with the extrusion ring 302 by bolts, the air supply pipe 303 corresponds to the extrusion ring 302, and the end of the air supply pipe 303 close to the extrusion ring 302 is fixedly installed with a limit ring for limiting the activity space of the piston 308. The piston 308 and the extrusion ring 302 are connected by a traction line 309. When the piston 308 moves to the right, the traction line 309 gradually tends to be straightened. When the piston 308 is completely located on the right side inside the force storage cylinder 203, the traction line 309 is completely straightened, and with the further movement of the piston 308, the extrusion ring 302 is driven to move through the traction line 309, so that the vent groove is exposed inside the force storage cylinder 203. The end of the force storage cylinder 203 away from the sealing plate 310 is installed with a relief valve. When the vent block 301 moves to the left, the relief valve is in an open state, and when the vent block 301 moves to the right, the relief valve is in a closed state.

[0044] Specifically, a partition sleeve 305 is passed through the inside of the air pipe 303 on the right side, and the partition sleeve 305 is connected to the air pipe 303 on the left side through a synchronization rod 304. A plurality of rectangular holes are provided on the outer surface of the partition sleeve 305, and the rectangular holes are arranged in a ring shape. Partition blocks 311 for squeezing the output pipe 306 are passed through the rectangular holes. The side of the partition block 311 away from the partition sleeve 305 is arc-shaped and contacts the edge of the right air pipe 303. When the partition sleeve 305 moves toward the right side, the partition block 311 is squeezed by the arc surface and the edge of the air pipe 303, so that the output pipe 306 is flattened, so that air cannot pass through, thereby staggering the inflation time of the power storage cylinder 203 and avoiding synchronous inflation of the four expansion bags 202.

[0045] like Figure 8 , Fig. 9As shown, a stabilizing plate 408 is fixedly welded to the inner bottom end of the central tube 205, a driving shaft 402 is arranged below the stabilizing plate 408, the driving shaft 402 is rotatably connected to the inner bottom end of the thermostatic box 1, a driving motor 204 is fixedly installed on the inner bottom end of the thermostatic box 1 through a clamp, the output shaft of the driving motor 204 is fixedly connected to a crown gear 401, a driven gear 403 is fixedly sleeved on the outer surface of the driving shaft 402, and the driven gear 403 is meshed with the crown gear 401;

[0046] A limit plate 407 is fixedly installed on the inner end of the central tube 205, and the limit plate 407 is located above the stabilizing plate 408, and a movable shaft 405 is passed through the center of the limit plate 407, and a sealing plug 406 is sleeved on the outer surface of the movable shaft 405. The outer surface of the sealing plug 406 and the inner wall of the central tube 205 are both smooth surfaces, and the two fit each other to increase air tightness and reduce friction. A corrugated sleeve 410 is fixedly welded to the bottom end of the movable shaft 405, and the corrugated sleeve 410 is connected to the limit plate 407 by a trigger spring 404. Two driving wheels 409 are rotatably installed on the upper end of the driving shaft 402 through a rotating shaft, and the driving wheels 409 are located at the trough of the corrugated sleeve 410. When the driving shaft 402 rotates, it drives the two driving wheels 409 to revolve. Since the driving shaft 402 cannot be moved upward When the driving wheel 409 rotates from the trough of the corrugated sleeve 410 to the crest, the corrugated sleeve 410 moves upward under the action of the extrusion force, and then moves from the crest to the trough. Under the elastic force of the trigger spring 404, the corrugated sleeve 410 moves downward again, and the outer surface of the movable shaft 405 is installed with a switch plate 411, and the switch plate 411 is located below the sealing plug 406. Specifically, the upper end of the switch plate 411 is fixedly sleeved with a sealing rubber ring, and the center of the sealing plug 406 is provided with a plurality of vents. When the switch plate 411 contacts the bottom of the sealing plug 406, the vents are sealed by the switch plate 411, and a limit block is fixedly installed on the upper end of the movable shaft 405, and the sealing plug 406 is located between the limit block and the switch plate 411;

[0047] When the movable shaft 405 moves upward, the on-off plate 411 blocks the vent hole at the center of the sealing plug 406, and then squeezes the air between the sealing plug 406 and the center tube 205. Then, when the movable shaft 405 moves downward, the on-off plate 411 no longer seals the vent hole, and drives the sealing plug 406 to move downward through the limit block, so that air re-enters the chamber between the sealing plug 406 and the center tube 205, and the cycle continues.

[0048] The working principle of the present invention is:

[0049] When in use, the test tube 2 containing the reagent is inserted into the interior of the movable sleeve 102, and its outer surface contacts the clamping plate 104, so that the clamping plate 104 rotates, and then the outer surface of the clamping plate 104 pushes the passive rod 108 to rotate, so that the extrusion block 107 moves toward the test tube 2 and contacts the outer surface of the test tube 2, and then the test tube 2 is clamped by the clamping plate 104 and the extrusion block 107, and the two-point fixation is implemented on the test tube 2, which further prevents the test tube 2 from shaking inside the movable sleeve 102;

[0050] At this time, the output end of the driving motor 204 drives the crown gear 401 to rotate, and the driven gear 403 drives the driving shaft 402 to rotate under the meshing action with the crown gear 401. Then, the driving shaft 402 drives the driving wheel 409 to rotate, so that the corrugated sleeve 410 moves up and down. Then, the corrugated sleeve 410 drives the sealing plug 406 to move up and down continuously through the movable shaft 405, repeatedly squeezing the air inside the central tube 205, and squeezing it into the inside of the gas delivery pipe 303 through the output pipe 306;

[0051] The air delivery pipe 303 transports air to the left chamber of the piston 308, so that the piston 308 moves away from the air guide pipe 206. When the piston 308 moves, the return spring 307 is compressed, and the traction line 309 gradually tends to be straightened. When the piston 308 is completely located on the right side of the storage cylinder 203, the traction line 309 is completely straightened, and as the piston 308 moves further, the extrusion ring 302 is driven to move through the traction line 309, so that the ventilation groove is exposed inside the storage cylinder 203. At this time, the air release valve is in a closed state;

[0052] At the same time, when the piston 308 is completely moved to the rightmost side of the power storage cylinder 203, the extrusion ring 302 pushes the left air delivery pipe 303 to move, and when the partition sleeve 305 moves to the right, the partition block 311 is squeezed by the arc surface and the edge of the air delivery pipe 303 to flatten the output pipe 306, so that the air cannot flow into the right power storage cylinder 203;

[0053] Then, the return spring 307 releases its elastic force, pushing the piston 308 toward the extrusion ring 302, and delivering the air inside the power storage cylinder 203 to the inside of the expansion bag 202 through the air guide tube 206, so that the expansion bag 202 expands, and then the water inside the liquid storage tank 201 begins to fluctuate under the action of the expansion bag 202. Since the test tube 2 is immersed in the water, the test tube 2 begins to shake in the fluctuating water, so as to achieve the shaking of the reagent inside the test tube 2. When the piston 308 pushes the extrusion ring 302 to move, it also drives the air delivery tube 303 to move, so that the air supply inside the power storage cylinder 203 on the right side is restored, so as to achieve the expansion process of multiple expansion bags 202 that are staggered.

[0054] At the same time, the extrusion ring 302 moves, causing the venting groove to retract into the interior of the air guide tube 206. The deflation valve is now in an open state, and the internally inflated expansion bag 202 begins to deflate.

[0055] When the reagent inside the test tube 2 is shaken and moved to a certain extent, the test tube 2 can be directly drawn out. During the drawing out process, the water on the outer surface of the test tube 2 is scraped off by the scraper ring 109.

[0056] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed in the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A multifunctional constant temperature mixer for molecular diagnosis in a laboratory, comprising a constant temperature box (1), characterized in that: A liquid storage box (201) is fixedly mounted on the inner end of the thermostatic box (1); an isolation ring (4) is arranged above the liquid storage box (201), and the isolation ring (4) is fixedly connected to the thermostatic box (1); a grid plate (101) is fixedly clamped on the inner end of the isolation ring (4); a plurality of holes are provided on the outer surface of the grid plate (101), and test tubes (2) are inserted into the holes; a swing device is provided below the grid plate (101) for driving the test tubes (2) to swing; and the liquid storage box (201) is fixedly mounted on the inner end of the isolation ring (4). The interior of the box (201) is filled with water. A heating pipe is arranged in the thermostatic box (1) for heating the water in the liquid storage box (201). The constant temperature control of the test tube (2) is achieved through the heat transfer of the water. A central tube (205) is fixedly installed at the inner bottom end of the thermostatic box (1). The central tube (205) is located below the liquid storage box (201). A stirring device is arranged between the liquid storage box (201) and the central tube (205) for stirring the liquid inside the liquid storage box (201).

2. A multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 1, characterized in that: The swing device comprises an inner sleeve (103), a plurality of movable rings (105) are arranged inside the inner sleeve (103), and the movable rings (105) correspond to the holes on the outer surface of the grid plate (101), the movable rings (105) are arranged in groups in a transverse manner, and two adjacent movable rings (105) are rotationally connected via a connecting shaft (106).

3. A multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 2, characterized in that: A movable sleeve (102) is rotatably mounted on the inner end of the movable ring (105); the rotation direction of the movable sleeve (102) is perpendicularly staggered with the rotation direction of two adjacent movable rings (105); the test tube (2) is inserted into the inside of the movable sleeve (102); and the test tube (2) can be rotated in any direction inside the liquid storage tank (201) through the staggered rotation of the movable ring (105) and the movable sleeve (102).

4. A multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 3, characterized in that: The bottom end of the movable sleeve (102) is rotatably connected to a plurality of clamping plates (104) via a rotating shaft. The plurality of clamping plates (104) are arranged in a ring shape, and the outer surfaces of the clamping plates (104) are fixedly connected to plate blades. The clamping plates (104) and the movable sleeve (102) are clamped by torsion springs. The inner end fixed sleeve of the movable sleeve (102) is provided with a wiper ring (109), and the wiper ring (109) is in contact with the outer surface of the test tube (2).

5. The multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 1, characterized in that: The stirring device comprises four expansion bags (202), and the four expansion bags (202) are respectively located at four corners inside the liquid storage tank (201). When the expansion bags (202) expand, the water surface inside the liquid storage tank (201) begins to fluctuate. A plurality of power storage cylinders (203) are fixedly installed at the bottom end of the liquid storage tank (201), and the power storage cylinders (203) correspond to the expansion bags (202). The power storage cylinders (203) and the expansion bags (202) are connected via an air guide tube (206).

6. A multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 5, characterized in that: An air delivery pipe (303) is provided inside the power storage cylinder (203), the output end of the central pipe (205) is connected to the air delivery pipe (303) via an output pipe (306), a sealing plate (310) is fixedly sleeved on the outer surface of the air delivery pipe (303), and a piston (308) is sleeved on the outer surface of the air delivery pipe (303).

7. The multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 6, characterized in that: The piston (308) and the sealing plate (310) are connected via a return spring (307); a ventilation block (301) is provided inside the air guide tube (206); a plurality of ventilation grooves are provided on the outer surface of the ventilation block (301); and when the ventilation block (301) moves to the right, the ventilation grooves are exposed inside the power storage cylinder (203).

8. The multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 7, characterized in that: An end of the vent block (301) close to the piston (308) is fixedly connected to an extrusion ring (302), the air supply pipe (303) corresponds to the extrusion ring (302), and an end of the air supply pipe (303) close to the extrusion ring (302) is fixedly installed with a limiting ring for limiting the movable space of the piston (308), and the piston (308) and the extrusion ring (302) are connected via a traction line (309).

9. The multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 1, characterized in that: A stabilizing plate (408) is fixedly mounted on the inner bottom end of the central tube (205); a driving shaft (402) is arranged below the stabilizing plate (408); the driving shaft (402) is rotatably connected to the inner bottom end of the thermostatic box (1); a driving motor (204) is fixedly mounted on the inner bottom end of the thermostatic box (1); an output shaft of the driving motor (204) is fixedly connected to a crown gear (401); a driven gear (403) is fixedly sleeved on the outer surface of the driving shaft (402); and the driven gear (403) is meshed with the crown gear (401).

10. The multifunctional constant temperature mixer for molecular diagnosis in laboratory according to claim 9, characterized in that: A limit plate (407) is fixedly installed on the inner end of the central tube (205), and the limit plate (407) is located above the stabilizing plate (408). A movable shaft (405) is passed through the center of the limit plate (407), and a sealing plug (406) is sleeved on the outer surface of the movable shaft (405). A corrugated sleeve (410) is fixedly connected to the bottom end of the movable shaft (405), and the corrugated sleeve (410) is connected to the limit plate (407) via a trigger spring (404). Two drive wheels (409) are rotatably installed on the upper end of the drive shaft (402).

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