Methods, equipment, and systems for determining the extraction electrode voltage

Abstract

This disclosure relates to a method, device, and system for determining the voltage of an extraction electrode. The continuous glucose monitoring device includes an extraction electrode attached to the surface of a user's skin. The method includes: obtaining a first applied voltage for the extraction electrode; determining the current value of a first current flowing through the surface of the user's skin when the first applied voltage is applied to the extraction electrode; and determining the first applied voltage as the applied voltage for the extraction electrode to extract the corresponding user's tissue fluid when the current value of the first current is within a preset current value range.

Description

Technical Field

[0001] This disclosure relates to blood glucose monitoring technology, and more specifically, to a method, device, and system for determining the voltage of an extraction electrode. Background Technology

[0002] Traditional continuous glucose monitoring devices are typically invasive methods for measuring blood glucose. This not only causes patient discomfort but also poses a risk of infection. Therefore, non-invasive continuous glucose monitoring (CGM) devices are being used by an increasing number of users.

[0003] Currently, non-invasive CGM devices use reverse iontophoresis extraction technology to extract tissue fluid. This technology generates an electric field by applying a certain voltage to the extraction electrodes, thereby extracting tissue fluid containing glucose. However, significant differences exist in skin impedance and conductivity among individual users, resulting in varying current magnitudes on different users' skin surfaces at the same voltage. This affects tissue fluid extraction and ultimately impacts the accuracy and stability of CGM devices in detecting blood glucose concentrations. Summary of the Invention

[0004] One object of the present invention is to provide a new technical solution for determining the extraction electrode voltage.

[0005] According to a first aspect of the present invention, a method for determining the voltage of an extraction electrode is provided, applied to a continuous glucose monitoring device, the continuous glucose monitoring device including an extraction electrode attached to the surface of a user's skin, the method comprising:

[0006] Obtain the first applied voltage for the extraction electrode;

[0007] When the first loading voltage is applied to the extraction electrode, the current value of the first current flowing through the surface of the user's skin is determined;

[0008] If the current value of the first current is within the preset current value range, the first applied voltage is determined as the applied voltage for the extraction electrode to extract the corresponding user tissue fluid.

[0009] Optionally, the method further includes:

[0010] If the value of the first current is not within the preset current value range, adjust the first loading voltage of the extraction electrode to obtain the second loading voltage of the extraction electrode;

[0011] When the extraction electrode is subjected to the second loading voltage, the current value of the second current flowing through the surface of the user's skin is determined;

[0012] If the current value of the second current is not within the preset current value range, continue to adjust the second loading voltage of the extraction electrode until the current value of the current flowing through the user's skin surface is within the preset current value range.

[0013] Optionally, the continuous glucose monitoring device locally stores a first applied voltage corresponding to different physiological characteristic information, wherein obtaining the first applied voltage for electrode extraction includes:

[0014] Obtain physiological characteristic information input by the user;

[0015] The first applied voltage for extracting the electrode is determined based on the physiological characteristic information input by the user and the first applied voltage corresponding to the different physiological characteristic information.

[0016] Optionally, the cloud server stores first applied voltages corresponding to different physiological characteristic information, wherein obtaining the first applied voltage for the extraction electrode includes:

[0017] Send a request to the terminal device to obtain the first applied voltage of the extraction electrode, so that the terminal device sends the request to the cloud server, wherein the request includes physiological characteristic information input by the user;

[0018] The cloud server receives the first applied voltage of the extraction electrode, wherein the first applied voltage of the extraction electrode is determined by the cloud server based on the physiological characteristic information input by the user and the first applied voltage corresponding to the different physiological characteristic information.

[0019] Optionally, the continuous glucose monitoring device further includes a sampling resistor through which the first current can flow, wherein determining the current value of the first current flowing through the user's skin surface includes:

[0020] Obtain the voltage value across the sampling resistor and the resistance value of the sampling resistor;

[0021] The current value of the first current flowing through the user's skin surface is determined based on the voltage value across the sampling resistor and the resistance value of the sampling resistor.

[0022] Optionally, the method further includes:

[0023] Obtain the user's identity information;

[0024] Establish a correspondence between the user's identity information and the applied voltage of the extraction electrode when extracting the corresponding user's tissue fluid, and store the correspondence.

[0025] Optionally, the method further includes:

[0026] The loading voltage for extracting the corresponding user's tissue fluid using the extraction electrode is sent to the terminal device, so that the terminal device sends the obtained user identification information and the loading voltage for extracting the corresponding user's tissue fluid using the extraction electrode to the cloud server. This allows the cloud server to establish a correspondence between the user's identification information and the loading voltage for extracting the corresponding user's tissue fluid using the extraction electrode, and to store the correspondence.

[0027] Optionally, the method further includes:

[0028] Determine whether the user is using the continuous glucose monitoring device for the first time to monitor blood glucose;

[0029] The process of obtaining the first applied voltage for the extraction electrode is only performed if it is determined that the user is using the continuous glucose monitoring device for the first time to monitor blood glucose.

[0030] If it is determined that the user is not using the continuous glucose monitoring device for the first time to monitor blood glucose, the applied voltage for the extraction electrode to extract tissue fluid for the user is obtained.

[0031] Tissue fluid is extracted using the applied voltage applied to the extraction electrode corresponding to the user.

[0032] According to a second aspect of the present invention, a continuous glucose monitoring device is provided, comprising a control unit and an extractable electrode, wherein the extractable electrode is attached to the surface of a user's skin, wherein...

[0033] The control unit is configured to: obtain a first loading voltage for the extraction electrode; determine the current value of a first current flowing through the user's skin surface when the extraction electrode is loaded with the first loading voltage; and determine the first loading voltage as the loading voltage for the extraction electrode to extract the corresponding user's tissue fluid when the current value of the first current is within a preset current value range.

[0034] According to a third aspect of the present invention, a continuous glucose monitoring system is provided, comprising: a continuous glucose monitoring device as described in the second aspect, a terminal device, and a cloud server, wherein...

[0035] The continuous glucose monitoring device establishes a communication connection with the terminal device, the terminal device establishes a communication connection with the cloud server, and the terminal device has an app corresponding to continuous glucose monitoring installed.

[0036] The continuous glucose monitoring device interacts with the cloud server through the terminal device.

[0037] The method for determining the extraction electrode voltage provided by this invention can obtain the loading voltage for extracting tissue fluid for different users, solving the problem of inconsistent tissue fluid extraction caused by differences in individual skin impedance and conductivity among different users, thereby improving the accuracy and stability of continuous glucose monitoring devices in detecting blood glucose concentration.

[0038] The features and advantages of the embodiments of this specification will become clear from the following detailed description of exemplary embodiments with reference to the accompanying drawings. Attached Figure Description

[0039] The accompanying drawings, which are incorporated in and form a part of this specification, illustrate embodiments of this specification and, together with their description, serve to explain the principles of these embodiments.

[0040] Figure 1 This is a schematic diagram of a continuous blood glucose monitoring system according to an embodiment of the present invention.

[0041] Figure 2 This is a schematic flowchart of a method for determining the extraction electrode voltage according to an embodiment of the present invention.

[0042] Figure 3 This is a schematic diagram of a continuous blood glucose monitoring device according to an embodiment of the present invention. Detailed Implementation

[0043] Various exemplary embodiments of this specification will now be described in detail with reference to the accompanying drawings.

[0044] The following description of at least one exemplary embodiment is merely illustrative and is in no way intended to limit the embodiments of this specification or their application or use.

[0045] It should be noted that similar labels and letters in the following figures indicate similar items; therefore, once an item is defined in one figure, it does not need to be discussed further in subsequent figures.

[0046] In one embodiment of the present invention, a method for determining the voltage of an extraction electrode is provided. This method is applied to a continuous glucose monitoring device. The continuous glucose monitoring device includes a control unit, an extraction electrode, and an electrochemical sensor. The extraction electrode is attached to the user's skin surface. The control unit controls the extraction electrode to apply a preset voltage to extract the user's tissue fluid. Glucose in the tissue fluid extracted by the extraction electrode can undergo an electrochemical reaction with a reactive enzyme in the electrochemical sensor. The control unit determines the user's blood glucose level based on the current generated by the electrochemical reaction.

[0047] according to Figure 1As shown, the continuous glucose monitoring device establishes a communication connection with the terminal device. This communication connection is wireless, such as via Bluetooth or Wi-Fi. The terminal device has a corresponding app installed. The continuous glucose monitoring device interacts with the cloud server through this app. For example, the continuous glucose monitoring device sends its monitored blood glucose values ​​to the cloud server through the app, and the cloud server sends pre-stored device parameters to the corresponding continuous glucose monitoring device through the app.

[0048] according to Figure 2 As shown, the method for determining the continuous extraction electrode voltage in this embodiment includes the following steps S210 to S230.

[0049] Step S210: Obtain the first applied voltage for the extraction electrode.

[0050] In some embodiments, the continuous glucose monitoring device locally stores first applied voltages corresponding to different physiological characteristic information. Step S210 specifically includes: obtaining physiological characteristic information input by the user; determining the first applied voltage for extracting the electrode based on the physiological characteristic information input by the user and the first applied voltages corresponding to different physiological characteristic information.

[0051] The physiological information input by the user refers to the input operations performed directly by the user on the continuous glucose monitoring device. Alternatively, the physiological information input by the user refers to the input operations performed by the user on the terminal device. According to... Figure 1 As shown, the continuous glucose monitoring device obtains the physiological characteristic information input by the user through a communication connection established with the terminal device. The user's physiological characteristic information includes gender and age.

[0052] In this embodiment, the first applied voltage of the extraction electrode is not a randomly obtained voltage, but a voltage obtained based on the user's physiological characteristic information. This makes the first applied voltage of the extraction electrode closer to the applied voltage of the extraction electrode when extracting the corresponding user's tissue fluid. This can reduce the number of subsequent operation steps to determine the applied voltage of the extraction electrode when extracting the corresponding user's tissue fluid, and improve the efficiency of determining the applied voltage of the extraction electrode when extracting the corresponding user's tissue fluid.

[0053] In some embodiments, the cloud server stores first loading voltages corresponding to different physiological characteristic information. Step S210 specifically includes: sending a request to the terminal device to obtain the first loading voltage of the extraction electrode, so that the terminal device sends the request to the cloud server, wherein the request includes physiological characteristic information input by the user; receiving the first loading voltage of the extraction electrode returned by the cloud server, wherein the first loading voltage of the extraction electrode is determined by the cloud server based on the physiological characteristic information input by the user and the first loading voltages corresponding to different physiological characteristic information.

[0054] The physiological characteristic information input by the user is the information entered by the user on the continuous glucose monitoring device. According to... Figure 1 As shown, the continuous glucose monitoring device sends a request to acquire physiological characteristic information input by the user to the terminal device, which then forwards the request to the cloud server. Upon receiving the request, the cloud server determines the first applied voltage for electrode extraction based on the user-input physiological characteristic information and the first applied voltage corresponding to different physiological characteristic information, and then sends the first applied voltage for electrode extraction to the terminal device. The terminal device then sends the first applied voltage for electrode extraction to the continuous glucose monitoring device.

[0055] The physiological characteristic information input by the user refers to the information entered by the user on the terminal device. According to... Figure 1 As shown, the continuous glucose monitoring device sends a request to acquire the first applied voltage for electrode extraction to the terminal device. Upon receiving the request, the terminal device adds the user-inputted physiological characteristic information to the request and sends the request, including the user-inputted physiological characteristic information, to the cloud server. Upon receiving the request, the cloud server determines the first applied voltage for electrode extraction based on the user-inputted physiological characteristic information and the first applied voltage corresponding to different physiological characteristic information, and then sends the first applied voltage for electrode extraction to the terminal device. The terminal device then sends the first applied voltage for electrode extraction to the continuous glucose monitoring device.

[0056] In this embodiment, the first applied voltage of the extraction electrode is not a randomly obtained voltage, but a voltage obtained based on the user's physiological characteristic information. This makes the first applied voltage of the extraction electrode closer to the applied voltage of the extraction electrode when extracting the corresponding user's tissue fluid. This can reduce the number of subsequent operation steps to determine the applied voltage of the extraction electrode when extracting the corresponding user's tissue fluid, and improve the efficiency of determining the applied voltage of the extraction electrode when extracting the corresponding user's tissue fluid.

[0057] Step S220: Under the condition of applying a first loading voltage to the extracted electrode, determine the current value of the first current flowing through the user's skin surface.

[0058] In some embodiments, the continuous glucose monitoring device further includes a sampling resistor through which a first current can flow. Step S220 specifically includes: obtaining the voltage value across the sampling resistor and the resistance value of the sampling resistor; and determining the current value of the first current flowing through the user's skin surface based on the voltage value across the sampling resistor and the resistance value of the sampling resistor.

[0059] The sampling resistor is a high-precision sampling resistor. The control unit of the continuous glucose monitoring device has the resistance value of the sampling resistor pre-stored. After the control unit obtains the voltage value across the sampling resistor through the analog-to-digital converter (ADC) unit, it determines the current value of the first current flowing through the user's skin surface based on the voltage value across the sampling resistor and the resistance value of the sampling resistor.

[0060] Step S230: If the current value of the first current is within the preset current value range, the first loading voltage is determined as the loading voltage for the extraction electrode to extract the corresponding user tissue fluid.

[0061] If the value of the first current is not within the preset current value range, adjust the first loading voltage of the extraction electrode to obtain the second loading voltage of the extraction electrode; with the second loading voltage applied to the extraction electrode, determine the value of the second current flowing through the user's skin surface; if the value of the second current is not within the preset current value range, continue to adjust the second loading voltage of the extraction electrode until the value of the current flowing through the user's skin surface is within the preset current value range.

[0062] The preset current value range is a pre-stored value range that can be set according to the needs of tissue fluid extraction.

[0063] If the value of the first current is not within the preset current range and is less than the lower limit of the preset current range, the first applied voltage of the extraction electrode is increased to obtain a second applied voltage of the extraction electrode. If the value of the first current is not within the preset current range and is greater than the upper limit of the preset current range, the first applied voltage of the extraction electrode is decreased to obtain a second applied voltage of the extraction electrode.

[0064] The method for determining the extraction electrode voltage provided by this invention can obtain the loading voltage for extracting tissue fluid for different users, solving the problem of inconsistent tissue fluid extraction caused by differences in individual skin impedance and conductivity among different users, thereby improving the accuracy and stability of continuous glucose monitoring devices in detecting blood glucose concentration.

[0065] In some embodiments, the method further includes: obtaining user identification information; establishing a correspondence between the user identification information and the applied voltage for extracting the corresponding user tissue fluid using the extraction electrode, and storing the correspondence.

[0066] The user's identification information is the information entered by the user on the continuous glucose monitoring device. Storing the correspondence between the user's identification information and the applied voltage for extracting the corresponding tissue fluid using the extraction electrode on the continuous glucose monitoring device allows the corresponding applied voltage for extracting tissue fluid to be obtained directly based on the user's identification information.

[0067] The user's identification information is the information entered by the user on the terminal device. The terminal device sends the user's identification information to the continuous glucose monitoring device, so that the continuous glucose monitoring device can establish a correspondence between the user's identification information and the applied voltage for extracting the corresponding tissue fluid using the extraction electrodes, and store this correspondence. This allows the application voltage for extracting tissue fluid using the corresponding extraction electrodes to be obtained directly based on the user's identification information.

[0068] In some embodiments, the method further includes: sending the loading voltage of the extraction electrode to extract the corresponding user tissue fluid to a terminal device, so that the terminal device sends the obtained user identification information and the loading voltage of the extraction electrode to extract the corresponding user tissue fluid to a cloud server, thereby enabling the cloud server to establish a correspondence between the user identification information and the loading voltage of the extraction electrode to extract the corresponding user tissue fluid, and store the correspondence.

[0069] The user's identification information is the information entered by the user on the continuous glucose monitoring device. The continuous glucose monitoring device sends the user's identification information and the applied voltage for extracting the corresponding tissue fluid to the terminal device, so that the terminal device can send the obtained user identification information and the applied voltage for extracting the corresponding tissue fluid to the cloud server.

[0070] The user's identification information is the information entered by the user on the terminal device. After receiving the applied voltage for the extraction electrode to extract the corresponding user's tissue fluid from the continuous glucose monitoring device, the terminal device sends the obtained user identification information and the applied voltage for the extraction electrode to extract the corresponding user's tissue fluid to the cloud server.

[0071] In some embodiments, the method further includes: determining whether the user is using the continuous glucose monitoring device for the first time to monitor blood glucose; obtaining a first applied voltage for the extraction electrode only if it is determined that the user is using the continuous glucose monitoring device for the first time to monitor blood glucose; obtaining an applied voltage for the extraction electrode to extract tissue fluid if it is determined that the user is not using the continuous glucose monitoring device for the first time to monitor blood glucose; and performing tissue fluid extraction using the applied voltage for the extraction electrode to extract tissue fluid.

[0072] If it is determined that the user is using a continuous glucose monitoring device for the first time, it can be determined that the continuous glucose monitoring device or the cloud server does not store the loading voltage for the corresponding user's extraction electrode to extract tissue fluid. Therefore, the above steps S210 to S230 need to be performed.

[0073] If it is determined that the user is not using a continuous glucose monitoring device for the first time, it can be determined that the continuous glucose monitoring device or cloud server does not store the loading voltage for extracting the corresponding user's tissue fluid with the extraction electrode. In this case, the loading voltage for extracting the corresponding user's tissue fluid with the extraction electrode can be obtained directly from the loading voltages for extracting each user's tissue fluid with the extraction electrode stored in the continuous glucose monitoring device or cloud server.

[0074] In this embodiment, by determining whether the user is using the continuous glucose monitoring device for the first time, and performing different operations accordingly to obtain the applied voltage for the extraction electrode to extract the corresponding user's tissue fluid, the user experience can be improved and the device performance optimized.

[0075] One embodiment of the present invention provides a continuous glucose monitoring device. According to... Figure 3 As shown, the continuous glucose monitoring device includes a control unit and an extraction electrode. The extraction electrode is attached to the user's skin surface. The control unit is used to: obtain a first applied voltage to the extraction electrode; determine the current value of a first current flowing through the user's skin surface when the extraction electrode is subjected to the first applied voltage; and determine the first applied voltage as the applied voltage for the extraction electrode to extract the corresponding user's tissue fluid when the first current value is within a preset current value range.

[0076] The control unit is an MCU (Microcontroller Unit).

[0077] according to Figure 3 As shown, the continuous glucose monitoring device also includes a DC / DC converter. The DC / DC converter is connected to the control unit via an IIC interface.

[0078] according to Figure 3 As shown, the continuous glucose monitoring device also includes a sampling resistor through which a first current can flow. The control unit is also used to obtain the voltage value across the sampling resistor and the resistance value of the sampling resistor; based on the voltage value across the sampling resistor and the resistance value of the sampling resistor, it determines the current value of the first current flowing through the user's skin surface.

[0079] One embodiment of the present invention provides a continuous blood glucose monitoring system. According to... Figure 1 As shown, the system includes a continuous glucose monitoring device, a terminal device, and a cloud server. The continuous glucose monitoring device establishes a communication connection with the terminal device, and the terminal device establishes a communication connection with the cloud server. The terminal device has a corresponding APP for continuous glucose monitoring installed.

[0080] Continuous glucose monitoring (CGM) devices interact with the cloud server via this app. For example, the CGM device sends its monitored blood glucose value to the cloud server through the app, and the cloud server sends pre-stored device parameters to the corresponding CGM device through the app. By storing and processing data on the cloud server, data integration and intelligent management are achieved, facilitating the analysis and optimization of large amounts of device and user data, and further enhancing the intelligence level of the monitoring system.

[0081] The various embodiments in this specification are described in a progressive manner. The same or similar parts between the various embodiments can be referred to each other. Each embodiment focuses on describing the differences from other embodiments.

[0082] The foregoing has described specific embodiments of this specification. Other embodiments are within the scope of the appended claims. In some cases, the actions or steps recited in the claims may be performed in a different order than that shown in the embodiments and may still achieve the desired result. Furthermore, the processes depicted in the drawings do not necessarily require the specific or sequential order shown to achieve the desired result. In some embodiments, multitasking and parallel processing are possible or may be advantageous.

[0083] Embodiments of this specification may be systems, methods, and / or computer program products. A computer program product may include a computer-readable storage medium having computer instructions stored thereon for causing a processor to implement various aspects of the embodiments of this specification.

[0084] Computer-readable storage media can be tangible devices capable of holding and storing computer instructions for use by computer instruction execution devices. Computer-readable storage media can be, for example—but not limited to—electrical storage devices, magnetic storage devices, optical storage devices, electromagnetic storage devices, semiconductor storage devices, or any suitable combination thereof. More specific examples (a non-exhaustive list) of computer-readable storage media include: portable computer disks, hard disks, random access memory (RAM), read-only memory (ROM), erasable programmable read-only memory (EPROM or flash memory), static random access memory (SRAM), portable compact disc read-only memory (CD-ROM), digital multifunction disc (DVD), memory sticks, floppy disks, mechanical encoding devices, such as punch cards or recessed protrusions storing computer instructions thereon, and any suitable combination thereof. The computer-readable storage media used herein are not to be construed as transient signals themselves, such as radio waves or other freely propagating electromagnetic waves, electromagnetic waves propagating through waveguides or other transmission media (e.g., light pulses through fiber optic cables), or electrical signals transmitted through wires.

[0085] The computer instructions described herein can be downloaded from computer-readable storage media to various computing / processing devices, or downloaded via a network, such as the Internet, local area network, wide area network, and / or wireless network, to an external computer or external storage device. The network may include copper cables, fiber optic cables, wireless transmission, routers, firewalls, switches, gateway computers, and / or edge servers. A network adapter card or network interface in each computing / processing device receives computer instructions from the network and forwards them to computer-readable storage media within the respective computing / processing device.

[0086] The flowcharts and block diagrams in the accompanying drawings illustrate the architecture, functionality, and operation of possible implementations of systems, methods, and computer program products according to various embodiments of this specification. In this regard, each block in a flowchart or block diagram may represent a module, segment, or portion of computer instructions, which contains one or more executable computer instructions for implementing a specified logical function. In some alternative implementations, the functions indicated in the blocks may occur in a different order than those indicated in the drawings. For example, two consecutive blocks may actually be executed substantially in parallel, and they may sometimes be executed in reverse order, depending on the functions involved. It should also be noted that each block in the block diagrams and / or flowcharts, and combinations of blocks in the block diagrams and / or flowcharts, may be implemented using a dedicated hardware-based system that performs the specified function or action, or using a combination of dedicated hardware and computer instructions. It will be known to those skilled in the art that implementation in hardware, implementation in software, and implementation using a combination of software and hardware are equivalent.

[0087] Various embodiments of this specification have been described above. These descriptions are exemplary and not exhaustive, nor are they limited to the disclosed embodiments. Many modifications and variations will be apparent to those skilled in the art without departing from the scope of the described embodiments. The terminology used herein is chosen to best explain the principles, practical application, or improvement of the technology in the market, or to enable others skilled in the art to understand the embodiments disclosed herein.

Claims

1. A method of determining an extracted electrode voltage, characterized by, The method is applied to a continuous blood glucose monitoring device, the continuous blood glucose monitoring device comprises a sampling electrode attached to a skin surface of a user, and the continuous blood glucose monitoring device locally stores first loading voltages corresponding to different physiological characteristic information, and the method comprises the following steps: obtaining the first loading voltage of the sampling electrode, comprising: obtaining user-input physiological characteristic information; determining the first loading voltage of the sampling electrode according to the user-input physiological characteristic information and the first loading voltages corresponding to the different physiological characteristic information; determining a current value of a first current flowing through the skin surface of the user when the sampling electrode is loaded with the first loading voltage; determining the first loading voltage as a loading voltage of the sampling electrode for sampling tissue fluid of a corresponding user when the current value of the first current is within a preset current value range.

2. The method of claim 1, wherein, The method further comprises: adjusting the first loading voltage of the sampling electrode to obtain a second loading voltage of the sampling electrode when the current value of the first current is not within the preset current value range; determining a current value of a second current flowing through the skin surface of the user when the sampling electrode is loaded with the second loading voltage; continuing to adjust the second loading voltage of the sampling electrode until the current value of the current flowing through the skin surface of the user is within the preset current value range when the current value of the second current is not within the preset current value range.

3. The method of claim 1, wherein, The cloud server stores first loading voltages corresponding to different physiological characteristic information, wherein the method further comprises: sending a request for obtaining the first loading voltage of the sampling electrode to a terminal device, so that the terminal device sends the request to the cloud server, wherein the request comprises user-input physiological characteristic information; receiving the first loading voltage of the sampling electrode returned by the cloud server, wherein the first loading voltage of the sampling electrode is determined by the cloud server according to the user-input physiological characteristic information and the first loading voltages corresponding to the different physiological characteristic information.

4. The method of claim 1, wherein, The continuous blood glucose monitoring device further comprises a sampling resistor, and the first current can flow through the sampling resistor, wherein the method further comprises: obtaining a voltage value across the sampling resistor and a resistance value of the sampling resistor; determining the current value of the first current flowing through the skin surface of the user according to the voltage value across the sampling resistor and the resistance value of the sampling resistor.

5. The method of claim 1, wherein, The method further comprises: obtaining identity information of the user; establishing a corresponding relationship between the identity information of the user and the loading voltage of the sampling electrode for sampling tissue fluid of a corresponding user, and storing the corresponding relationship.

6. The method of claim 1, wherein, The method further comprises: sending the loading voltage of the sampling electrode for sampling tissue fluid of a corresponding user to a terminal device, so that the terminal device sends the obtained identity information of the user and the loading voltage of the sampling electrode for sampling tissue fluid of a corresponding user to a cloud server, and then the cloud server establishes a corresponding relationship between the identity information of the user and the loading voltage of the sampling electrode for sampling tissue fluid of a corresponding user, and stores the corresponding relationship.

7. The method according to any one of claims 1 to 6, characterized in that, The method further comprises: determining whether the user is using the continuous glucose monitoring device to monitor blood glucose for the first time; only when it is determined that the user is using the continuous glucose monitoring device to monitor blood glucose for the first time, the first loading voltage of the extraction electrode is obtained; when it is determined that the user is not using the continuous glucose monitoring device to monitor blood glucose for the first time, the loading voltage of the extraction electrode corresponding to the user for extracting tissue fluid is obtained; tissue fluid extraction is performed using the loading voltage of the extraction electrode corresponding to the user for extracting tissue fluid.

8. A continuous glucose monitoring device, characterized by, The continuous glucose monitoring device locally stores first loading voltages corresponding to different physiological characteristic information, comprises a control unit and an extraction electrode, wherein the extraction electrode is attached to the skin surface of a user, and the control unit is configured to: obtain the first loading voltage of the extraction electrode, comprising: obtaining the physiological characteristic information input by the user; determining the first loading voltage of the extraction electrode according to the physiological characteristic information input by the user and the first loading voltages corresponding to the different physiological characteristic information; determining the current value of the first current flowing through the skin surface of the user when the extraction electrode is loaded with the first loading voltage; and determining the first loading voltage as the loading voltage of the extraction electrode for extracting tissue fluid of the corresponding user when the current value of the first current is within a preset current value range.

9. A continuous glucose monitoring system, characterized by comprise: The continuous glucose monitoring device, the terminal device and the cloud server of claim 8, wherein the continuous glucose monitoring device establishes a communication connection with the terminal device, the terminal device establishes a communication connection with the cloud server, and the terminal device is installed with an APP corresponding to continuous glucose monitoring, and the continuous glucose monitoring device performs data interaction with the cloud server through the terminal device.

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