Detection equipment and liquid drop generation system

Abstract

The invention relates to a detection device and a droplet generation system. The detection equipment and the liquid drop generation system respectively comprise a liquid supply device, wherein the liquid supply device comprises a container, a liquid nozzle which can be driven to move along a preset path and is provided with a first position and a second position, and a locking device for keeping the liquid nozzle at the first position; the liquid supply device has a first state and a second state; in the first state, the liquid nozzle is located at a first position and is tightly connected with the container, and an internal channel of the liquid nozzle is communicated with the liquid outlet part of the container; in the second state, the liquid nozzle is located at the second position, the liquid nozzle is separated from the container, the internal channel of the liquid nozzle is disconnected from the liquid outlet part of the container, specifically, the detection equipment can be PCR equipment, and the liquid supply device is an oil supply device. According to the detection equipment and the liquid drop generation system, the liquid container can be conveniently dismounted and mounted, meanwhile, liquid scattering during replacement can be avoided, and the detection efficiency is effectively improved.

Description

Technical Field

[0001] The present invention relates to detection devices such as PCR devices, and particularly to a liquid supply device and a droplet generation system for detection devices. Background Art

[0002] In detection devices such as digital PCR devices, in order to generate droplets and the like, a liquid supply device is provided to supply liquids (such as formulation oil). Taking a digital PCR device as an example, the liquid supply device of the prior art generally includes a container having a liquid accommodation space, a lid that can be detached from the container, and an infusion tube. The infusion tube penetrates from inside the container to the outside of the container and is used to connect to a backend mechanism outside the container. With this structural arrangement, when replacing the container and disassembling it, the lid needs to be opened and the infusion tube needs to be drawn out of the container. During this process, the drawn-out infusion tube will carry some liquid out of the container and cause the liquid to spill and contaminate the working area. At the same time, the installation of this structure requires inserting the infusion tube into the container, making it difficult to achieve quick and convenient assembly. Summary of the Invention

[0003] The technical problem to be solved by the present invention is to provide an improved detection device, the liquid supply device of which can be replaced conveniently and liquid spillage can be avoided.

[0004] To solve the above technical problems, a technical solution adopted by the present invention is: A detection device has a liquid passage and a liquid supply device for supplying liquid to the liquid passage. The liquid supply device includes a container having a liquid accommodation space and a liquid outlet portion, a liquid nozzle that can be driven to move along a preset path and has a first position and a second position, and a locking device for keeping the liquid nozzle in the first position. The liquid nozzle has an internal passage; the liquid supply device has a first state and a second state; when in the first state, the liquid nozzle is in the first position, the liquid nozzle is tightly connected to the container, and the internal passage of the liquid nozzle communicates with the liquid outlet portion of the container; when in the second state, the liquid nozzle is in the second position, the liquid nozzle is separated from the container, and the internal passage of the liquid nozzle is disconnected from the liquid outlet portion of the container.

[0005] According to a specific embodiment of the present invention, the detection device includes a support. The support has a first mounting portion, and the liquid nozzle is disposed on the first mounting portion. In another specific embodiment, the support has both a first mounting portion and a second mounting portion. Similarly, the liquid nozzle is disposed on the first mounting portion, and the second mounting portion is used to accommodate and / or support the container.

[0006] According to a preferred embodiment of the present invention, the preset path extends in the up-and-down direction, particularly vertically; when the liquid nozzle is in the first position, the liquid nozzle can be located above or below the container. Correspondingly, the liquid outlet part is arranged at the top or bottom of the container; preferably, when the liquid nozzle is located above the container, a conduit is also provided in the container, and one end of the conduit communicates with the liquid outlet part, and the other end extends to near the bottom of the container.

[0007] Preferably, the liquid supply device further includes a driving device for driving the liquid nozzle to move along the preset path between the first position and the second position. The driving device can be a manual driving device, an electric driving device, or a driving device that can be both manual and electric.

[0008] In the present invention, the locking device is not particularly limited and can adopt those conventional in the art. However, according to a preferred embodiment of the present invention, the locking device is arranged between the driving device and the container. In a specific and preferred embodiment, the locking device includes a clamping groove provided on the container and a clamping head connected to the driving device. When in the first state, the clamping head is inserted into the clamping groove.

[0009] Furthermore, the driving device includes a driving member rotatably arranged and a touch ring formed on the outer periphery of the liquid nozzle. When the driving member rotates, it drives the liquid nozzle to move linearly by abutting against the touch ring.

[0010] Furthermore, the detection device includes a support. The support has a first mounting portion. The liquid nozzle is arranged on the first mounting portion. The driving member has a driving arm and a connecting portion rotatably connected to the first mounting portion. The touch ring includes an upper touch ring and a lower touch ring arranged at intervals and located on both sides of the driving arm respectively.

[0011] Preferably, the driving device further includes an operating handle connected to the driving member. The locking device includes a clamping groove provided on the container and a clamping head formed at one end of the operating handle. When in the first state, the clamping head is inserted into the clamping groove.

[0012] When the driving device is an electric driving device or a driving device that can be both manual and electric, the driving device further includes an electric push rod connected to the driving member.

[0013] According to a specific embodiment of the present invention, the liquid outlet part includes a liquid outlet hole and a sealing ring arranged on the hole wall of the liquid outlet hole.

[0014] Preferably, the liquid nozzle includes a liquid pipe having the internal channel. The liquid pipe faces the sealing ring, and one end of the liquid pipe facing the sealing ring has an inclined surface; the end face of the sealing ring facing the liquid pipe also has an inclined surface; when in the first state, the inclined surface of the liquid pipe is pressed against the inclined surface of the sealing ring.

[0015] Furthermore, an installation hole is provided on the container, a container cover is fixedly provided in the installation hole, and a liquid outlet hole is provided on the container cover.

[0016] Preferably, a ventilation hole is further provided on the container cover.

[0017] Preferably, an edge of the installation hole is provided with a hole wall located outside the container, and an outer periphery of the container cover is provided with a convex edge that abuts against an end face of the hole wall.

[0018] Preferably, the detection device further includes a guiding seat for guiding the movement of the liquid nozzle along a preset path, and the guiding seat is arranged around the liquid nozzle.

[0019] Preferably, the detection device is a PCR device, and the liquid supply device is an oil supply device.

[0020] On the other hand, the present invention provides a droplet generation system, which includes the liquid supply device as described above.

[0021] Due to the application of the above technical solutions, the present invention has the following advantages compared with the prior art: The present invention adopts an improved liquid supply device, which can not only facilitate the disassembly and installation of the container for providing liquid during the container replacement process, but also avoid problems such as liquid spillage during disassembly and replacement, which helps to ensure the smooth progress of detection and improve work efficiency. Description of the Drawings

[0022] Attached Figure 1 Overall structural schematic diagram of the digital PCR device.

[0023] Attached Figure 2 Partial front view schematic diagram of the detection device of the present invention.

[0024] Attached Figure 3 A-A sectional view schematic diagram of the detection device of the present invention in the first state.

[0025] Attached Figure 4 Enlarged schematic diagram of part B of the detection device of the present invention.

[0026] Attached Figure 5 A-A sectional view schematic diagram of the detection device of the present invention in the second state.

[0027] Attached Figure 6 Enlarged schematic diagram of part C of the detection device of the present invention.

[0028] In the above drawings: 1. container; 2. liquid nozzle; 3. support; 4. first mounting part; 5. second mounting part; 6. conduit; 7. liquid outlet; 8. driving member; 9. upper trigger ring; 10. lower trigger ring; 11. operating handle; 12. snap-in groove; 13. snap joint; 14. sealing ring; 15. liquid outlet; 16. container cover; 17. guide seat; 18. X-axis slide rail; 19. Y-axis slide rail; 20. base; 21. mobile detection platform; 22. micro-droplet generation unit; 23. optical detection unit; 24. mobile bearing platform; 25. thermal cycle unit; 26. driving device; 27. driving screw; 28. oil supply device; 29. ​​steady flow injection device. DETAILED DESCRIPTION

[0029] In order to enable those skilled in the art to better understand the scheme of the present invention, the technical scheme in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention.

[0030] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0031] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0032] As attached Figure 1The digital PCR device shown includes a base 20 having an X-axis slide rail 18 and a Y-axis slide rail 19, a moving detection platform 21 slidably disposed on the base 20 via the X-axis slide rail 18, a driving device 26 for driving the movement of the moving detection platform 21, a micro-droplet generation unit 22 disposed on the moving detection platform 21, an optical detection unit 23 disposed on the moving detection platform 21, a moving bearing platform 24 disposed in the base 20 via the Y-axis slide rail 19, a driving lead screw 27 for driving the moving bearing platform 24, and a plurality of thermal cycling units 25 disposed on the moving bearing platform 24. The micro-droplet generation unit 22 for performing micro-droplet treatment on a sample includes an oil supply device 28 for providing formulation oil and a steady-flow sample injection device 29 for sucking the sample and injecting the sample into the formulation oil to form micro-droplets. The oil supply device 28 and the injection micro-tube in the steady-flow sample injection device 29 are connected by a pipeline, so as to introduce the formulation oil into the injection micro-tube to evacuate the gas therein.

[0033] In the above digital PCR device, the oil supply device 28 adopts the following with a liquid passage and a liquid supply device for supplying liquid to the liquid passage.

[0034] As shown in the appendix Figure 2 to the appendix Figure 6 shown, the liquid supply device includes a container 1, which has a liquid accommodation space and a liquid outlet part 7. The liquid accommodation space contains the liquid to be provided, such as oil. The liquid outlet part 7 communicates the inside and outside of the container 1, and the liquid in the container 1 can be led out of the container 1 through the liquid outlet part 7. The liquid supply device further includes a liquid nozzle 2, which has an internal channel. The liquid nozzle 2 is movably disposed outside the container 1, and it can be driven to move along a preset path. Moreover, the liquid nozzle 2 also has a first position and a second position. When the liquid nozzle 2 moves along the preset path, it can switch between the first position and the second position. At the same time, the liquid supply device further includes a locking device, which is used to keep the liquid nozzle 2 in the first position when the liquid nozzle 2 moves to the first position. The liquid nozzle 2 is used to connect the rear-end liquid path system to transport oil.

[0035] This liquid supply device has the first state as shown in the appendix Figure 3 and the appendix Figure 4 shown and the second state as shown in the appendix Figure 5 and the appendix Figure 6 shown. When in the first state, the liquid nozzle 2 is in the first position, the liquid nozzle 2 is tightly connected to the container 1, and the internal channel of the liquid nozzle 2 communicates with the liquid outlet part 7 of the container 1. When in the second state, the liquid nozzle 2 is in the second position, the liquid nozzle 2 is separated from the container 1, and the internal channel of the liquid nozzle 2 is disconnected from the liquid outlet part 7 of the container 1.

[0036] The locking device includes a mating clamping groove 12 and a clamping head 13. The clamping groove 12 is provided on the container 1, and the clamping head 13 is connected to the driving device. When the liquid supply device is in the first state, the clamping head 13 is inserted into the clamping groove 12, and at this time, the driving device cannot move freely, so as to keep the liquid nozzle 2 in the first position by restricting the driving device.

[0037] The detection device includes a support 3 for supporting and installing each component. The support 3 has a first mounting portion 4, and the liquid nozzle 2 is arranged on the first mounting portion 4 and can move relative to the first mounting portion 4. The first mounting portion 4 can be in the shape of a plate, with a through hole opened thereon, and the liquid nozzle 2 is passed through the through hole. The support 3 can also have a second mounting portion 5 while having the above-mentioned first mounting portion 4, and the second mounting portion 5 is used to accommodate and / or support the container 1.

[0038] The preset path of the movement of the liquid nozzle 2 extends in the up and down direction, that is, the liquid nozzle 2 can move in the up and down direction. The liquid nozzle 2 includes a liquid pipe with an internal channel, and the axial direction of the liquid pipe is set along the movement direction of the liquid nozzle 2, that is, the up and down direction. When the liquid nozzle 2 is in the first position, the liquid nozzle 2 is located above or below the container 1. Correspondingly, the liquid outlet portion 7 is arranged at the top or bottom of the container 1. In this embodiment, the scheme that the liquid nozzle 2 is located above the container 1 is adopted. At this time, a conduit 6 is also arranged in the container 1. One end (upper end) of the conduit 6 is communicated with the liquid outlet portion 7 of the container 1, and the other end (lower end) extends to the lower half of the container 1, close to the bottom of the container 1, and is preferably set as an inclined end face and contacts the bottom of the container 1. The lower end of the liquid nozzle 2 is used to connect the container 1, and the upper end is used to connect the rear liquid path system. For example, a connection bayonet is arranged at the upper end of the liquid nozzle 2, and the connection bayonet can be connected to the rear liquid path system through a flexible hose.

[0039] The liquid nozzle 2 can move between the first position and the second position along the preset path. To facilitate the stable and controllable movement of the liquid nozzle, the liquid supply device further includes a driving device to drive the liquid nozzle 2. The driving device can be a manual driving device, an electric driving device, or a driving device that can be both manual and electric.

[0040] In this embodiment, the driving device includes a driving member 8, a touch ring, and an operating handle 11. The driving member 8 is movably arranged and drives the liquid nozzle 2 to move when it moves. In this embodiment, the driving member 8 is rotatably connected to the first mounting portion 4 of the support 3 through a rotating shaft. The driving member 8 includes a connecting portion rotatably connected to the first mounting portion 4 at one end and a driving arm connected to the other end of the connecting portion. The axis of the connecting portion forms a certain angle with the axis of the driving arm. In this embodiment, the axis of the connecting portion is substantially perpendicular to the axis of the driving arm, thus forming a bent arm. The rotating shaft and the connecting portion are located on one side of the liquid nozzle 2, and the driving arm extends from both sides of the middle of the liquid nozzle 2 to the other side of the liquid nozzle 2. Two parallel rib plates can be arranged on the first mounting portion 4 for mounting the rotating shaft to enable the driving member 8 to be rotatably mounted. The touch ring is arranged on the outer periphery of the liquid nozzle 2 and can be in contact with the driving member 8, specifically in contact with the driving arm of the driving member 8. Thus, when the driving member 8 rotates, it can push the touch ring and then drive the liquid nozzle 2 to move. The touch ring includes an upper touch ring 9 arranged on one side of the driving member 8 and a lower touch ring 10 arranged on the other side of the driving member 8. The two touch rings 9 and 10 are arranged at intervals to respectively enable the liquid nozzle 2 to move in two moving directions, up and down. When the driving member 8 rotates upward, it pushes the upper touch ring 9 from below to drive the liquid nozzle 2 to move upward; when the driving member 8 rotates downward, it pushes the lower touch ring 10 from above to drive the liquid nozzle 2 to move downward. The movement of the driving member 8 can be manually driven by a person or electrically driven. In this embodiment, the driving device is a manually driven device, and it further includes an operating handle 11. The operating handle 11 is connected to the driving arm of the driving member 8, and the operation of the driving member 8 can be realized by operating the operating handle 11. One end of the operating handle 11 is fixedly connected to the driving member 8, and a protrusion for a person to apply a force can be arranged in the middle of the operating handle 11. Based on the solution including the operating handle 11, the clamping joint 13 in the locking device is formed at one end of the operating handle 11. When in the first state, the operating handle 11 rotates towards the direction of the container 1, and the clamping joint 13 at one end of it is embedded into the clamping groove 12 on the container 1. The surface of the clamping groove 12 in contact with the clamping joint 13 is an inclined surface, so that the clamping joint 13 is not easily slid out of the clamping groove 12 freely under the action of this inclined surface, but needs to apply a certain magnitude of external force to be able to slide out of the clamping groove 12 to achieve unlocking.

[0041] In order to ensure that the liquid nozzle 2 moves along a preset path and reduce deviation, the detection device further includes a guiding seat 17 for guiding the movement of the liquid nozzle 2 along the preset path. The guiding seat 17 is arranged around the liquid nozzle 2 and can be installed on the first mounting portion 4.

[0042] When the driving device is an electric driving device or a driving device that can be manual or electric, the driving device further includes an electric push rod connected to the driving member 8. The two ends of the electric push rod can be respectively hinged to the first mounting portion 4 and the driving member 8. When the electric push rod extends or contracts, it can drive the driving member 8 to rotate.

[0043] The liquid outlet portion 7 of the container 1 includes a liquid outlet hole 15 and a sealing ring 14, and the sealing ring 14 is arranged on the hole wall of the liquid outlet hole 15. In this embodiment, a mounting hole is formed in the container 1, and a container cover 16 is fixedly arranged at the mounting hole, and the liquid outlet hole 15 is formed in the container cover 16. More specifically, a hole wall located outside the container 1 is provided at the edge of the mounting hole, and a convex edge that abuts against the end face of the hole wall is provided on the outer periphery of the container cover 16, so that the container cover 16 is mounted through the cooperation of the convex edge and the end face of the hole wall. The container cover 16 has a relatively large thickness, and the axial length of the liquid outlet hole 15 formed therein is greater than the axial length of the sealing ring 14. The sealing ring 14 is fixed on the hole wall in the middle of the liquid outlet hole 15 through a stepped structure. Above the liquid outlet hole 15 and the sealing ring 14, the end of the liquid pipe of the liquid nozzle 2 facing the sealing ring 14 of the container 1 has an inclined surface, and the end face of the sealing ring 14 facing the liquid nozzle 2 also has an inclined surface. When in the first state, the inclined surface of the liquid pipe presses against the inclined surface of the sealing ring 14, causing the sealing ring 14 to undergo elastic deformation to achieve axial and circumferential sealed connection. A ventilation hole is also formed in the container cover 16 to communicate the inside and outside of the container 1, and a pair of ventilation holes can be formed on both sides opposite to the liquid outlet hole 15. For the unused container 1, a sealing film covering the liquid outlet hole 15 and the ventilation hole is provided on the container cover 16 to ensure the sealing of the unused container 1 during transportation and prevent liquid leakage.

[0044] The process of replacing the container 1 of the above liquid supply device is as follows: Unlock the locking device, and manually or electrically rotate the driving member 8 upward. During this process, drive the liquid nozzle 2 to move upward under the guiding action of the guiding seat 17 through the upper trigger ring 9, so that the lower end of the liquid nozzle 2 disengages from the liquid outlet part 7 of the container 1. Peel off the sealing film on the container cover 16 of the unused container 1 and place the container 1 at the designated position on the support 3. Manually or electrically rotate the driving member 8 downward. During this process, drive the liquid nozzle 2 to move downward until the limit position under the guiding action of the guiding seat 17 through the lower trigger ring 10, so that the lower end of the liquid nozzle 2 is in close contact with the sealing ring 14 by entering the liquid outlet hole 15 to achieve a tight connection with the container 1. At this time, the internal channel of the liquid nozzle 2 is communicated with the liquid outlet hole 15 of the liquid outlet part 7 of the container 1, and the clamping head 13 at the end of the operating handle 11 is inserted into the clamping groove 12 to lock the position of the liquid nozzle 2. At this time, the gas in the liquid nozzle 2 and the internal conduit 6 of the container 1 can be emptied into the inner side of the container 1 through the rear-end liquid path system, and then oil is injected into the rear end. The air vent hole on the container 1 can timely replenish the pressure in the container 1 to make the internal and external pressures of the container 1 equal. During the process of replacing the container 1, the liquid in the container 1 will not spill and pollute the detection environment, and this process is convenient to operate and takes less time.

[0045] In the above liquid supply device, the conduit 6 that touches the bottom is built in the container 1, which can maximize the utilization of the liquid and reduce liquid residue and waste. The sealing ring 14 is embedded in the pore wall of the liquid outlet hole 15 on the container cover 16 or is secondarily injection molded in the liquid outlet hole 15. Through the cooperation between the inclined surface on the sealing ring 14 and the inclined surface on the liquid nozzle 2, the sealed connection between the liquid nozzle 2 and the container 1 is realized.

[0046] Multiple sets (for example, two sets) of the above liquid supply devices can be set on the same detection device to realize the supply function of different liquids or the supply and standby supply functions of the same liquid.

[0047] The above liquid supply device is not limited to being applied to digital PCR equipment, and can also be applied to other detection equipment that needs to set up a liquid supply device.

[0048] The above embodiments are only used to illustrate the technical concept and characteristics of the present invention, and their purpose is to enable those who are familiar with this technology to understand the content of the present invention and implement it accordingly, and cannot be used to limit the protection scope of the present invention. All equivalent changes or modifications made according to the spirit and essence of the present invention should be covered within the protection scope of the present invention.

Claims

1. A detection device, comprising a liquid passage and a liquid supply device for supplying liquid to the liquid passage, wherein the liquid supply device comprises a container having a liquid accommodating space and a liquid outlet, characterized in that: The liquid supply device further comprises a liquid nozzle which can be driven to move along a preset path and has a first position and a second position, and a locking device for keeping the liquid nozzle in the first position, the liquid nozzle having an internal passage; the liquid supply device has a first state and a second state; When in the first state, the liquid nozzle is in the first position, the liquid nozzle is tightly connected to the container, and the internal channel of the liquid nozzle is connected to the liquid outlet of the container; when in the second state, the liquid nozzle is in the second position, the liquid nozzle is separated from the container, and the internal channel of the liquid nozzle is disconnected from the liquid outlet of the container.

2. The detection device according to claim 1, characterized in that: The detection device comprises a support, the support has a first mounting portion, the liquid nozzle is arranged on the first mounting portion, or the support has both the first mounting portion and a second mounting portion, the second mounting portion is used to accommodate and / or support the container.

3. The detection device according to claim 1, characterized in that: The preset path extends in the up-down direction; when the liquid nozzle is in the first position, the liquid nozzle is located above or below the container, and correspondingly, the liquid outlet is arranged at the top or bottom of the container; when the liquid nozzle is located above the container, the container also has a conduit, one end of the conduit is connected to the liquid outlet, and the other end extends to near the bottom of the container.

4. The detection device according to claim 1, characterized in that: The liquid supply device further comprises a driving device for driving the liquid nozzle to move along the preset path between the first position and the second position. The driving device is a manual driving device or an electric driving device or a driving device that can be both manual and electric.

5. The detection device according to claim 4, characterized in that: The locking device comprises a clamping groove arranged on the container and a clamping joint connected to the liquid nozzle or the driving device. When in the first state, the clamping joint is embedded in the clamping groove.

6. The detection device according to claim 4, characterized in that: The driving device comprises a rotatably arranged driving member and an actuating ring formed on the outer periphery of the liquid nozzle. When the driving member rotates, it drives the liquid nozzle to perform linear motion by contacting the actuating ring.

7. The detection device according to claim 6, characterized in that: The detection device includes a support, the support has a first mounting portion, the liquid nozzle is arranged on the first mounting portion, the driving member has a driving arm and a connecting portion rotatably connected to the first mounting portion, and the trigger ring includes an upper trigger ring and a lower trigger ring which are arranged at intervals and respectively located on both sides of the driving arm.

8. The detection device according to claim 6, characterized in that: The driving device also includes an operating handle connected to the driving member, and the locking device includes a clamping groove arranged on the container and a clamping joint formed at one end of the operating handle. When in the first state, the clamping joint is embedded in the clamping groove.

9. The detection device according to claim 1, characterized in that: The liquid outlet portion comprises a liquid outlet hole and a sealing ring arranged on the hole wall of the liquid outlet hole.

10. The detection device according to claim 9, characterized in that: The liquid nozzle includes a liquid tube having the internal channel, the liquid tube is opposite to the sealing ring, and one end of the liquid tube facing the sealing ring has a slope; the end surface of the sealing ring facing the liquid tube also has a slope; when in the first state, the slope of the liquid tube is pressed against the slope of the sealing ring.

11. The detection device according to claim 9, characterized in that: The container is provided with a mounting hole, a container cover is fixedly arranged in the mounting hole, and the liquid outlet is provided on the container cover.

12. The detection device according to claim 11, characterized in that: The container cover is also provided with an air hole; and / or, the edge of the mounting hole is provided with a hole wall located outside the container, and the outer periphery of the container cover is provided with a convex edge that abuts against the end surface of the hole wall.

13. The detection device according to claim 1, characterized in that: The detection device also includes a guide seat for guiding the liquid nozzle to move along a preset path, and the guide seat is arranged around the liquid nozzle.

14. The detection device according to claim 1, characterized in that: The detection equipment is a PCR equipment, and the liquid supply device is an oil supply device.

15. A droplet generation system, comprising a liquid supply device, characterized in that: The liquid supply device is as described in any one of claims 1 to 13.

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