Tumor examination sampling and inspection device

Abstract

The invention relates to the technical field of medical instruments, in particular to a tumor examination sampling and inspection device which comprises a positioning shell and a supporting frame, the positioning shell is detachably connected with the supporting frame, a pushing thorn barrel is arranged in the positioning shell, a driving assembly is arranged at the top in the positioning shell, and the driving assembly is in signal connection with a control system. A fixed cylinder is fixedly connected to the bottom of the inner wall of the pushing cylinder, a sampling displacement block is slidably connected to the inner wall of the fixed cylinder, a first air bag is further arranged in the pushing cylinder and communicates with a first air pipe, one end of the first air pipe communicates with an air pressure exchange assembly, and the bottom of the air pressure exchange assembly communicates with a pressure storage assembly; a mechanical piercing mechanism is combined with ultrasonic feedback, accurate piercing depth control is achieved, the automation of a tumor cell sampling mechanism and a sample pushing mechanism is designed, the sampling and piercing process serves as a driving source of all the mechanisms, the operation complexity is reduced, and the operation efficiency is improved. And convenience is provided for follow-up inspection work of tumor cells.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a tumor testing sampling and inspection device. Background Art

[0002] Tumor testing and sampling is an indispensable part of tumor diagnosis and treatment. By sampling and analyzing tumor tissue, doctors can understand the type of tumor, the degree of malignancy, and whether there are gene mutations, so as to develop personalized treatment plans for patients.

[0003] Existing sampling and inspection devices are usually designed to be fixedly connected to the mechanism for loading the sampling needle and the operating frame that serves as a support, so as to achieve stable sampling puncture by the fixing effect of the operating frame. However, due to the lack of an accurate depth control mechanism, it is difficult for the operator to accurately grasp the insertion depth of the needle. If the insertion is too shallow, the tumor tissue cannot be fully obtained; on the contrary, if the insertion is too deep, the surrounding normal tissue may be damaged. In addition, after the cytological examination sampling, if the process of removing the sample requires an additional step to push the syringe to squeeze out the tumor cells, it adds complexity to the operation. In the process of pushing the syringe to expel the tumor cells inside the syringe, due to the relatively fragile physical properties of the tumor cells and the uneven pressure on the cells caused by the small space inside the syringe, the tumor cells are easily mechanically compressed and broken.

[0004] Therefore, it is necessary to propose a tumor detection sampling and inspection device, which is provided with a puncture mechanism to accurately control the puncture depth, and to increase the protection of the sample to improve the rationality of the detection and increase the accuracy of the tumor detection. Summary of the invention

[0005] To solve the above problems, the present invention provides a tumor inspection sampling and delivery device, which combines a mechanized insertion mechanism with ultrasonic feedback to achieve precise control of the insertion depth, and designs an automated mechanism for tumor cell sampling and sample ejection. The sampling and insertion process is used as the driving source for each mechanism, which reduces the complexity of the operation and facilitates the subsequent inspection of tumor cells.

[0006] In order to achieve the above-mentioned purpose, the technical scheme of the present invention is as follows: a tumor inspection sampling and delivery device, comprising a positioning shell and a support frame, the support frame comprising a vertical rod and a rotating arm, the positioning shell and the rotating arm are detachably connected at one end away from the vertical rod, an angle adjustment component for adjusting the sampling insertion angle is provided at the connection between the positioning shell and the rotating arm, a piercing cylinder with a bottom opening is provided in the positioning shell, a gap is provided between the outer wall of the piercing cylinder and the inner wall of the positioning shell, a connecting seat is fixedly connected to the top wall of the positioning shell, a driving component for driving the vertical displacement of the piercing cylinder is provided on the connecting seat, and the driving component signal is connected to a control system for presetting and controlling the piercing depth;

[0007] The bottom of the inner wall of the pushing and stabbing cylinder is fixedly connected to a fixed cylinder, and the bottom of the pushing and stabbing cylinder is detachably connected to a symmetrical fixed block, which is used to clamp the cylinder of the sampling needle, and the inner wall of the fixed cylinder is slidably connected to a sampling displacement block, and the gap between the sampling displacement block and the inner top wall of the fixed cylinder is a push-pull cavity, and the gap between the outer top wall of the fixed cylinder and the inner top wall of the pushing and stabbing cylinder is a compression cavity, and a first air bag with an annular structure is arranged in the compression cavity, and the outer wall of the first air bag is fixedly connected to the inner side wall of the fixed cylinder, and the side wall of the first air bag is connected to a first air pipe, and the first air pipe is connected to an air pressure exchange component for utilizing the displacement of the pushing and stabbing cylinder to drive work for energy conversion, and a pressure storage component is connected to the bottom of the air pressure exchange component, and when the pushing and stabbing cylinder is vertically displaced, the air pressure exchange component and the pressure storage component respectively store the elastic potential energy for absorbing tumor cells and the air pressure for pushing out tumor cells, and the side wall of the push-pull cavity is provided with an electromagnetic valve for controlling its connection state with each component, and the electromagnetic valve is connected with a control system signal.

[0008] The technical principle of the above scheme is as follows: multi-angle rotation positioning is achieved through the support frame; the sampling insertion angle is adjusted through the design of the angle adjustment component; the driving component that drives the vertical displacement of the piercing cylinder is driven by the design of the driving component and the control system, and the vertical displacement of the piercing cylinder is controlled by the control system that presets and controls the piercing depth, so as to achieve precise control of the sampling depth; the pushing support and fixation of the sampling needle are achieved through the design of the piercing cylinder and the fixed cylinder; the bottom of the air pressure exchange component is connected to a pressure storage component for storing air pressure used to push out tumor cells; when the piercing cylinder is vertically displaced, the first airbag will deform, thereby storing or releasing elastic potential energy; when the first airbag releases elastic potential energy, the air pressure can be transmitted to the pressure storage component through the air pressure exchange component to provide power for pushing out tumor cells; the solenoid valve is connected to the control system signal, and the opening and closing of the solenoid valve can be controlled according to the preset program and instructions.

[0009] The above scheme has the following beneficial effects:

[0010] 1. In this solution, the combination of the drive component and the control system achieves precise control of the insertion depth. Medical staff can preset the insertion depth, and the control system automatically controls the operation of the drive component to ensure that each sampling can reach the predetermined depth. This not only improves the efficiency of sampling, but also avoids the problem of insufficient sampling or damage to surrounding normal tissues due to shallow or deep insertion.

[0011] 2. In this solution, the design of the pushing cylinder and the fixed cylinder is that during the sampling process, the vertical displacement of the pushing cylinder will squeeze the first airbag, thereby driving the air pressure exchange component to convert energy, respectively storing the elastic potential energy for absorbing tumor cells and the air pressure for pushing out tumor cells, which not only simplifies the sampling process, but also improves the efficiency and quality of sampling.

[0012] 3. In this solution, the solenoid valve is set so that medical staff can control the connection status between the push-pull chamber and each component according to actual needs. This flexibility enables the device to adapt to different sampling needs, further improves the accuracy and efficiency of sampling, and realizes the operation mode of completing sampling and sample pushing with one button.

[0013] Furthermore, the driving assembly includes a driving groove opened on the connecting seat, a servo motor is fixedly connected in the driving groove, a threaded rod is coaxially fixedly connected to the output shaft of the servo motor, the threaded rod is away from the connecting seat and penetrates the top wall of the pushing cylinder to extend into the compression chamber, the connecting seat bottom wall is fixedly connected to the connecting cylinder, the threaded rod is close to the connecting seat and is rotatably connected to the bottom end of the connecting cylinder, the top wall of the pushing cylinder is provided with a ball nut located at the point where the threaded rod penetrates, the outer wall of the ball nut is fixedly connected to the pushing cylinder, and the pushing cylinder is threadedly connected to the threaded rod through the ball nut.

[0014] Beneficial effects: This solution uses a servo motor to drive the puncture cylinder to perform vertical displacement, and the control system presets and controls the penetration depth, which solves the problem of inaccurate penetration depth caused by manual operation in existing sampling and inspection devices, improves and ensures that the needle can accurately penetrate the tumor tissue and fully obtain tumor samples, while avoiding the risk of damaging surrounding normal tissues, thereby improving the safety and reliability of sampling.

[0015] Furthermore, the bottom end of the threaded rod is fixedly connected to a limiting block.

[0016] Beneficial effect: Through the design of the limit block, on the one hand, it prevents the threaded rod and the piercing cylinder from falling off each other and causing the drive to fail. On the other hand, the distance between the limit block and the top of the threaded rod, that is, the threshold of the insertion depth, helps medical staff to judge the model of the sampling needle and realizes precise control of the vertical displacement of the piercing cylinder.

[0017] Furthermore, the air pressure exchange component includes a sealing ring connected to the first air pipe, the sealing ring is sleeved on the middle part of the outer wall of the piercing cylinder, a piston is provided inside the sealing ring, the piston and the inner wall of the sealing ring are slidably matched, the piston separates the chamber in the sealing ring into a first chamber and a second chamber from top to bottom, the connection point between the first air pipe and the sealing ring is located in the first chamber, the bottom wall of the second chamber is connected to the second air pipe, and the second air pipe is connected to the pressure storage component at one end away from the second chamber.

[0018] Beneficial effect: When the thrust cylinder moves vertically downward, the first airbag is compressed, and the air pressure is released to the first chamber through the first air tube, pushing the piston downward, thereby transferring the air pressure in the first chamber to the second chamber and storing it in the pressure storage component through the second air tube. When it is necessary to push out tumor cells, the pressure storage component releases the air pressure, pushing the piston upward through the second air tube, thereby using the air pressure difference in the first chamber to push out the tumor cells, achieving efficient conversion and utilization of energy.

[0019] Furthermore, the pressure storage assembly includes a pressure storage ring connected to the second air pipe, a one-way air valve is provided in the second air pipe, the one-way air valve allows gas to flow from the second chamber to the pressure storage ring, the pressure storage ring is also sleeved on the outside of the pushing cylinder and is located below the sealing ring, a plurality of first springs are provided in the pressure storage ring, both ends of the first springs are respectively fixedly connected to the inner top wall and the inner bottom wall of the pressure storage ring, a side wall of the pressure storage ring close to the pushing cylinder is connected to a third air pipe, the end of the third air pipe away from the pressure storage ring passes through the side walls of the pushing cylinder and the fixed cylinder and extends into the push-pull cavity, and the connection state of the third air pipe is controlled by the solenoid valve.

[0020] Beneficial effects: The setting of the one-way air valve avoids air pressure backflow and leakage, and improves the efficiency and stability of air pressure storage; in addition, the design of the first spring can absorb and release energy during the air pressure storage and release process, making the air pressure change more stable and continuous, and reducing the impact of air pressure fluctuations on the sampling process.

[0021] Furthermore, a plurality of second springs are provided in the second chamber, and the two ends of the second springs are fixedly connected to the bottom wall of the piston and the inner bottom wall of the sealing ring respectively. The side wall of the second chamber close to the piercing cylinder is also connected to a fourth air pipe, and the end of the fourth air pipe away from the second chamber is connected to the solenoid valve.

[0022] Beneficial effect: The design of the second spring provides additional buffering and reset force for the piston during the vertical displacement process. When sucking tumor cells, the second spring releases elastic potential energy to push the piston upward, generating negative pressure in the push-pull cavity, so that the sampling displacement block drives the pull rod of the sampling needle to rise, realizing an automated sampling process and reducing the complexity of manual sampling operation by medical staff.

[0023] Furthermore, a third spring is provided in the push-pull cavity, and two ends of the third spring are respectively fixedly connected to the top wall of the fixed cylinder and the top wall of the sampling displacement block.

[0024] Beneficial effects: The design of the third spring allows the sampling displacement block to absorb and release energy when it encounters resistance from tumor tissue, reducing damage to the tumor tissue caused by sudden stops or accelerations of the sampling displacement block, helping to protect the tumor tissue and improve the quality of sampling and the accuracy of cytological tests. In addition, since the hardness of tumor tissue may vary from individual to individual, the third spring can provide more buffering and reset force to reduce damage to the tumor tissue when encountering harder tumor tissue; and when encountering softer tumor tissue, the third spring can maintain the stable movement of the sampling displacement block to ensure the accuracy of sampling.

[0025] Furthermore, a buffer layer is fixedly connected inside the positioning shell, and a temperature sensor is also fixedly connected inside the positioning shell, and the temperature sensor is connected to the control system signal.

[0026] Beneficial effects: The buffer layer can absorb and disperse impact forces, reduce wear and damage between components, as well as the effects of external forces, extend the service life of the device, and help maintain the stability and accuracy of the sampling process; the temperature sensor can transmit real-time monitored temperature data to the control system, and doctors can adjust the sampling strategy or conduct further analysis based on this data.

[0027] Furthermore, an ultrasonic probe is detachably connected to the bottom end of the positioning shell, and the ultrasonic probe is connected to the control system signal.

[0028] Beneficial effects: The ultrasonic probe can scan and display the location, shape and size of tumor tissue in real time, providing doctors with intuitive visual feedback. Doctors can accurately adjust the position and depth of the sampling displacement block according to the scanning results of the ultrasonic probe to ensure that the sampling process is accurate.

[0029] Further, the control system includes an ultrasonic image feedback unit, a depth preset and control unit, a gas valve driving module and a test temperature monitoring module;

[0030] An ultrasonic image feedback unit, used for receiving signals transmitted by the ultrasonic probe and converting these signals into digital data to generate a two-dimensional image of the sampling needle under the patient's skin;

[0031] The depth preset and control unit is used to receive the preset insertion depth value input by the medical staff through the operation interface, convert it into the driving power of the servo motor, and send a corresponding control signal to the servo motor;

[0032] The air valve driving module is used to receive instructions from the depth preset and control unit, and when the sampling needle reaches the target sampling depth, sends a driving signal to the solenoid valve to control the connection with the fourth airway, and when tumor cells need to be removed, sends a driving signal to control the solenoid valve to connect with the third airway;

[0033] The sample temperature monitoring module is used to receive the temperature signal collected by the temperature sensor, monitor the temperature inside the positioning shell, and monitor the sample inspection environment temperature within 18-25°C. When the temperature exceeds the preset range, the sample temperature monitoring module triggers an alarm to notify medical staff.

[0034] Beneficial effects: The intelligent and automated control system simplifies the operating process, reduces the workload of medical staff, improves the accuracy and safety of the sampling process, enhances the confidence and job satisfaction of medical staff, ensures high-quality collection and storage of samples, and provides a reliable basis for subsequent cytological testing.

[0035] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 This is a schematic diagram of the overall structure of an embodiment of a tumor detection sampling and delivery device of the present invention;

[0037] Figure 2 It is an axonometric cross-sectional view of the positioning shell of the embodiment of the tumor detection sampling and delivery device of the present invention;

[0038] Figure 3 The present invention is a tumor detection sampling and inspection device embodiment Figure 2 The enlarged view of the connection relationship between the chambers at A in the middle;

[0039] Figure 4 This is a schematic diagram of the position of the fixed block in the embodiment of the tumor detection sampling and delivery device of the present invention;

[0040] Figure 5 This is a schematic diagram of the operation of the control system in the embodiment of the tumor detection sampling and delivery device of the present invention.

[0041] The figure marks in the drawings of the specification include: 1, positioning shell; 2, support frame; 201, vertical rod; 202, rotating arm; 3, pushing cylinder; 4, connecting seat; 5, fixed cylinder; 6, sampling displacement block; 7, push-pull chamber; 8, compression chamber; 9, first air bag; 10, first air pipe; 11, solenoid valve; 12, driving groove; 13, servo motor; 14, threaded rod; 15, connecting cylinder; 16, ball nut; 17, limit block; 18, ultrasonic probe; 19, sealing ring; 1901, first chamber; 1902, second chamber; 20, piston; 21, second air pipe; 22, pressure storage ring; 23, one-way air valve; 24, first spring; 25, third air pipe; 26, second spring; 27, fourth air pipe; 28, third spring; 29, buffer layer; 30, fixed block. DETAILED DESCRIPTION

[0042] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0043] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0044] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0045] The following is further described in detail through specific implementation methods:

[0046] Embodiment 1:

[0047] As attached Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown: a tumor inspection sampling and delivery device, including a positioning shell 1 and a support frame 2, the support frame 2 includes a vertical rod 201 and a rotating arm 202, the bottom end of the rotating arm 202 is spherically jointed with the top end of the vertical rod 201, and the rotating arm 202 can achieve 360° rotation and positioning, the positioning shell 1 is detachably connected to the rotating arm 202 at one end away from the vertical rod 201 through a snap structure, because the patient's tumor position and tumor direction cannot be determined, through the design of the rotating arm 202, the medical staff can adjust the rotating arm 202 to align with the patient's tumor by rotating, and the other end of the vertical rod 201 can be connected to the ground counterweight, and can also be designed as a clamping structure fixed to the bed armrest or other position, so that the vertical rod 201 plays a fixing role, thereby providing force support for subsequent sampling operations in the positioning shell 1.

[0048] The positioning shell 1 is provided with a push-thrust cylinder 3 with an opening at the bottom, and a symmetrical fixing block 30 is detachably connected to the bottom of the push-thrust cylinder 3. Figure 4As shown, before sampling, the medical staff aligns the barrel handle of the sampling needle with the bottom of the pushing cylinder 3, and fixes the sampling needle to the bottom of the pushing cylinder 3 through the detachable connection of the fixing block 30, so that the vertical displacement of the pushing cylinder 3 can drive the sampling needle to move as a whole, and a gap is provided between the outer wall of the pushing cylinder 3 and the inner wall of the positioning shell 1, and a connecting seat 4 is welded on the inner top wall of the positioning shell 1, and a driving component for driving the vertical displacement of the pushing cylinder 3 is provided on the connecting seat 4, and a fixed cylinder 5 is welded on the bottom of the inner wall of the pushing cylinder 3, and the inner wall of the fixed cylinder 5 is connected by a slider groove structure. A sampling displacement block 6 is slidably connected, and a plurality of elastic clamping blocks are welded along the circumference of the bottom end of the sampling displacement block 6. Before sampling, the medical staff pushes the sampling needle to the sampling state, and then installs the top end of the sampling needle in the plurality of clamping blocks. During the sampling process, the driving assembly drives the puncture cylinder 3 toward the patient's tumor, so as to achieve the effect of piercing the patient's skin and pushing the sampling needle to the tumor during the sampling process. Mechanical push replaces manual operation, so as to achieve the effect of the sampling needle accurately and efficiently piercing the patient's skin and reaching the tumor for sampling.

[0049] For the drive in this process, the control of the penetration depth is particularly important. For this purpose, a driving component is designed to include a driving groove 12 opened on the connecting seat 4, in which a servo motor 13 is fixedly connected by screws. The servo motor 13 signal is connected to a control system for presetting and controlling the penetration depth. The output shaft of the servo motor 13 is coaxially fixedly connected to a threaded rod 14 through a coupling. A connecting tube 15 is welded to the bottom wall of the connecting seat 4. One end of the threaded rod 14 close to the connecting seat 4 is rotatably connected to the bottom end of the connecting tube 15 through a bearing. One end of the threaded rod 14 away from the connecting seat 4 passes through the top wall of the pushing and stabbing cylinder 3 and extends to the inside of the pushing and stabbing cylinder 3 where a limiting block 17 is welded. The top wall of the pushing and stabbing cylinder 3 is provided with a ball nut 16 located at the point where the threaded rod 14 passes through. The outer wall of the ball nut 16 is welded to the pushing and stabbing cylinder 3, and the pushing and stabbing cylinder 3 is threadedly connected to the threaded rod 14 through the ball nut 16. First, the medical staff presets the insertion depth according to the patient's tumor condition, and then converts the insertion depth into the driving power of the servo motor 13 through processing by the control system, and then transmits the driving signal to the servo motor 13 to drive the threaded rod 14 to rotate. Through the thread cooperation of the ball nut 16 and the threaded rod 14, the work of the rotation of the threaded rod 14 is converted into the work of the vertical displacement of the pushing and piercing cylinder 3, thereby achieving the vertical driving effect of the pushing and piercing cylinder 3. The servo motor 13 has the advantages of high precision, high stability and easy programming control. Through the design of the servo motor 13, the insertion depth can be accurately controlled to ensure that the movement of the pushing and piercing cylinder 3 is both stable and accurate during the sampling process.

[0050] In particular, combined Figure 2 and Figure 3As shown, by utilizing the work done by the vertical driving of the stabbing cylinder 3 in the process, that is, the change in the distance between the top wall of the limit block 17 and the inner top wall of the stabbing cylinder 3, the gap between the outer top wall of the fixed cylinder 5 and the inner top wall of the stabbing cylinder 3 is designed to be a compression chamber 8, and a first air bag 9 with an annular structure is arranged in the compression chamber 8. The outer bottom wall of the first air bag 9 is adhered and fixed to the top wall of the limit block 17, and the outer wall of the first air bag 9 close to the threaded rod 14 is a folded structure. The folded structure is conducive to compression deformation to squeeze out the air inside it, and the side wall of the first air bag 9 is connected to the first air pipe 10, and the first air pipe 10 is far A sealing ring 19 is connected to one end of the first airbag 9, and the sealing ring 19 is welded and fixed to the middle part of the outer wall of the piercing cylinder 3. A piston 20 is arranged in the sealing ring 19, and the piston 20 slides with the inner wall of the sealing ring 19. The piston 20 divides the chamber in the sealing ring 19 into a first chamber 1901 and a second chamber 1902 from top to bottom. The connection point between the first air pipe 10 and the sealing ring 19 is located in the first chamber 1901, and the bottom wall of the second chamber 1902 is connected to a second air pipe 21. The second air pipe 21 is connected to an elastic pressure storage ring 22 at one end away from the second chamber 1902. A one-way valve 23 is provided in the second air pipe 21, and the one-way valve 23 allows the gas to flow from the sealing ring 19 to the pressure storage ring 22. The pressure storage ring 22 is also welded and fixed to the outside of the piercing cylinder 3 and is located below the sealing ring 19. A first spring 24 is provided in the pressure storage ring 22, and the two ends of the first spring 24 are respectively welded to the inner top wall and the inner bottom wall of the pressure storage ring 22; in the process of displacement of the piercing cylinder 3 to the patient's tumor, the distance between the top wall of the limit block 17 and the inner top wall of the piercing cylinder 3 gradually decreases, that is, the volume of the first airbag 9 is gradually compressed. At this time, part of the first airbag 9 The gas is pressed into the first chamber 1901 of the sealing ring 19. As the volume of the gas in the first chamber 1901 increases, that is, the air pressure in the first chamber 1901 increases, the piston 20 is pushed to move toward the second chamber 1902. The gas originally in the second chamber 1902 enters the pressure storage ring 22 through the one-way air valve 23, and the volume of the elastic pressure storage ring 22 increases accordingly. Due to the existence of the one-way air valve 23, the pressure storage ring 22 has the effect of storing the air pressure force, that is, the pressure storage ring 22 can store the work used to push the sampling needle into the patient's body.

[0051] For the release of stored energy, the side wall of the pressure storage ring 22 is designed to be connected with a third air pipe 25. The end of the third air pipe 25 away from the pressure storage ring 22 passes through the side walls of the push cylinder 3 and the fixed cylinder 5 and extends to the fixed cylinder 5 to be connected with a push-pull cavity 7. The push-pull cavity 7 is located between the top wall of the sampling displacement block 6 and the inner top wall of the fixed cylinder 5. The joint between the sampling displacement block 6 and the side wall of the fixed cylinder 5 is provided with a sealing strip for ensuring the airtightness of the push-pull cavity 7. The connection between the third air pipe 25 and the push-pull cavity 7 is provided with an electromagnetic valve 11. The electromagnetic valve 11 is connected to the control system signal. The electromagnetic valve 11 makes the connection between the push-pull cavity 7 and the pressure storage ring 22 normally closed. When the tumor cells in the sampling needle need to be discharged after sampling is completed, the control system sends a driving signal to the solenoid valve 11, so that the solenoid valve 11 connects the push-pull chamber 7 with the pressure storage ring 22. At this time, the air pressure stored in the pressure storage ring 22 due to the increase in volume is released into the push-pull chamber 7. At this time, the gas volume in the push-pull chamber 7 increases, that is, the air pressure increases, so that the sampling displacement block 6 will move away from the top wall of the fixed cylinder 5, thereby realizing the movement of the tumor cells in the sampling needle. On the one hand, it eliminates the need for medical staff to press the sampling syringe by themselves when removing tumor cells, simplifies the operating steps, and improves the efficiency of sampling. On the other hand, this process utilizes the work of driving the vertical displacement of the push-pull cylinder 3 to achieve efficient conversion and recycling of energy.

[0052] In addition, it is designed that a plurality of second springs 26 are provided in the second chamber 1902, and the two ends of the second springs 26 are respectively welded to the bottom wall of the piston 20 and the inner bottom wall of the sealing ring 19, and the side wall of the second chamber 1902 close to the pushing cylinder 3 is also connected to a fourth air pipe 27, and the end of the fourth air pipe 27 away from the second chamber 1902 is connected to the electromagnetic valve 11. When the sampling needle reaches the specified depth, the control system sends a driving signal to the electromagnetic valve 11 to drive the electromagnetic valve 11 to connect the second chamber 1902 and the push-pull chamber 7. Since the plurality of second springs 26 are compressed by the displacement of the piston 20 during the insertion of the sampling needle, and the second chamber 1902 is always closed in combination with the one-way air valve 23 and the electromagnetic valve 11, the plurality of second springs 26 are in a compressed energy storage state. After the second chamber 1902 and the push-pull chamber 7 are connected, the second chamber 1 The air pressure in 902 changes towards restoring the equilibrium state, that is, the second spring 26 releases the stored pressure, causing the piston 20 to move toward the first chamber 1901 and absorb the gas in the push-pull chamber 7 into the second chamber 1902. At this time, the volume of gas in the push-pull chamber 7 is reduced, and a pulling force is generated on the sampling displacement block 6 close to the inner top wall of the fixed cylinder 5, simulating the behavior of medical staff manually extracting tumor cells, eliminating the manual sampling operation of medical staff. At the same time, the deeper the sampling needle penetrates into the patient's skin, the greater the extraction force required for sampling. The design adjusts the negative pressure suction force in the push-pull chamber 7 according to the compression degree of the first airbag 9 (that is, the penetration depth of the sampling needle). The less the first airbag 9 is compressed, the greater the negative pressure suction force of the push-pull chamber 7, thereby increasing the probability of successful suction and improving the sampling efficiency.

[0053] Since tumor cells have relatively fragile physical properties, excessive suction force or squeezing force during the suction and discharge process will damage the tumor cells. For this reason, a third spring 28 is designed to be provided in the push-pull cavity 7. The two ends of the third spring 28 are respectively welded to the top wall of the fixed cylinder 5 and the top wall of the sampling displacement block 6. During the suction and discharge of tumor cells, due to the elastic characteristics of the third spring 28, when the volume of the push-pull cavity 7 is reduced, the third spring 28 will apply a reverse elastic supporting force. Conversely, the third spring 28 will also apply a reverse elastic pulling force to reduce the damage to the patient caused by the sudden change of air pressure (excessive suction force), as well as the damage to the tumor cells caused by the excessive pushing force.

[0054] In addition, due to the existence of the solenoid valve 11, when the control system controls the signal of the solenoid valve 11 and controls the solenoid valve 11 to connect the two chambers, the size of the air pressure force (the force that drives the sampling displacement block 6 to move) can also be controlled by controlling the flow area (opening size) of the solenoid valve 11.

[0055] Embodiment 2:

[0056] As attached Figure 2As shown, the difference from Example 1 is that the bottom end of the positioning shell 1 is detachably connected to an ultrasonic probe 18 through a snap-on structure, and the ultrasonic probe 18 is connected to the control system signal. During the insertion of the sampling needle, the ultrasonic probe 18 transmits ultrasonic waves and receives the reflected signals, and transmits them to the control system. The control system generates an image of the sampling needle under the patient's skin, and realizes depth feedback of the sampling needle, which helps medical staff observe the insertion depth of the sampling needle and is more conducive to medical staff to formulate corresponding treatment strategies to deal with sudden or unknown diseases.

[0057] Embodiment 3:

[0058] As attached Figure 2 As shown, the difference from Example 2 is that, for the inspection of tumor cells, since the samples may be affected by mechanical squeezing or temperature changes during storage and transportation, resulting in cell rupture or biomolecule degradation, a buffer layer 29 is designed to be adhered and fixed in the positioning shell 1, and the buffer layer 29 is made of biocompatible silicone. In addition, a temperature sensor is fixedly connected to the positioning shell 1 by screws, and the temperature sensor is connected to the control system signal.

[0059] Embodiment 4:

[0060] As attached Figure 1 As shown, the difference from Example 3 is that due to the different tumor growth positions, it is impossible to confirm the insertion angle of the sampling needle by fixing a certain direction. Therefore, an angle adjustment component for adjusting the insertion angle of the sampling needle is designed at the connection between the positioning shell 1 and the rotating arm 202. The angle adjustment component includes a limit ring welded to the rotating arm 202, a limit rod welded to the inner side of the limit ring, and the limit rod is hinged to the limit ring at one end away from the limit ring. The bottom end of the positioning shell 1 can fit with the inner wall of the limit ring, a rotating ring is provided above the limit ring, and a number of connecting rods are provided between the rotating ring and the limit ring. The two ends of the connecting rods are respectively welded to the bottom end of the rotating ring and the top end of the limiting ring. The ball joint on the inner wall of the rotating ring has two asymmetric electric control cylinders, and the electric control cylinders are both connected to the control The signal of the control system is connected, and the output shaft of the electric control cylinder is fixedly connected to the limit block 17 through a coupling. The limit blocks 17 are all fitted to the side wall of the positioning shell 1. After the patient's tumor is detected by means of CT or ultrasound, the sampling puncture point position and the puncture angle can be preliminarily determined. When the puncture point position and the puncture angle are determined, the limit circle is framed to frame the patient's puncture point, and the position of the limit circle is aligned with the puncture point position, which ensures that the sampling needle pushed out from the bottom end of the positioning shell 1 can be accurately aligned with the puncture point position. As for the adjustment of the puncture angle, the control system is based on the puncture angle and the patient's tumor position, which is converted into the output power of the two electric control cylinders, and the inclination angle of the positioning shell 1 is effectively controlled by the two electric control cylinders to achieve the control of the puncture angle.

[0061] Embodiment 5:

[0062] As attached Figure 5 As shown, the difference from Example 4 is that the control system includes an ultrasonic image feedback unit, a depth preset and control unit, a gas valve driving module and a test temperature monitoring module.

[0063] The ultrasonic image feedback unit is responsible for receiving the signals transmitted by the ultrasonic probe 18. When the probe emits ultrasonic waves and receives reflected signals, these signals are converted into digital data and transmitted to the control system. The image processing algorithm in the control system processes these data to generate a two-dimensional image of the sampling needle under the patient's skin, which helps medical staff to intuitively observe the penetration depth, position and relative relationship of the sampling needle with the surrounding tissues.

[0064] The depth preset and control unit is responsible for receiving the preset insertion depth value input by the medical staff through the operation interface, and converting and calculating it into the driving power of the servo motor 13, and then sending a corresponding control signal to the servo motor 13 to drive the vertical displacement of the puncture cylinder 3 to ensure that the sampling needle can accurately reach the predetermined depth.

[0065] The air valve driving module is responsible for receiving instructions from the depth preset and control unit. When the sampling needle reaches the target sampling depth, it sends a driving signal to the solenoid valve 11 to control the connection to the fourth airway 27. When tumor cells need to be removed, it sends a driving signal to control the solenoid valve 11 to connect to the third airway 25.

[0066] The sample temperature monitoring module is responsible for receiving the temperature signal collected by the temperature sensor, monitoring the temperature inside the positioning shell 1, and ensuring that the sample is kept within the temperature range of 18-25°C during storage and transportation to prevent cell rupture or biomolecule degradation. When the temperature exceeds the preset range, the sample temperature monitoring module triggers an alarm and notifies the medical staff through the operation interface.

[0067] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection of the invention.

Claims

1. A tumor inspection sampling and delivery device, comprising a positioning shell (1) and a support frame (2), the support frame (2) comprising a vertical rod (201) and a rotating arm (202), the positioning shell (1) and the rotating arm (202) are detachably connected at one end away from the vertical rod (201), characterized in that: An angle adjustment component for adjusting the sampling insertion angle is provided at the connection between the positioning shell (1) and the rotating arm (202); a piercing cylinder (3) with a bottom opening is provided inside the positioning shell (1); a gap is provided between the outer wall of the piercing cylinder (3) and the inner wall of the positioning shell (1); a connecting seat (4) is fixedly connected to the top wall of the positioning shell (1); a driving component for driving the piercing cylinder (3) to move vertically is provided on the connecting seat (4); and a control system for presetting and controlling the piercing depth is connected to the signal of the driving component; The bottom of the inner wall of the piercing cylinder (3) is fixedly connected to a fixed cylinder (5), and the bottom of the piercing cylinder (3) is detachably connected to a symmetrical fixed block (30), which is used to clamp the cylinder of the sampling needle. The inner wall of the fixed cylinder (5) is slidably connected to a sampling displacement block (6), and the gap between the sampling displacement block (6) and the inner top wall of the fixed cylinder (5) is a push-pull cavity (7), and the gap between the outer top wall of the fixed cylinder (5) and the inner top wall of the piercing cylinder (3) is a compression cavity (8), and a first airbag (9) of an annular structure is arranged in the compression cavity (8), and the outer wall of the first airbag (9) is fixed to the inner side wall of the fixed cylinder (5). The first airbag (9) is connected to a first air tube (10) on the side wall thereof; an end of the first air tube (10) away from the first airbag (9) is connected to an air pressure exchange component for converting energy by driving the displacement of the thrust cylinder (3); a pressure storage component is connected to the bottom of the air pressure exchange component; when the thrust cylinder (3) is vertically displaced, the air pressure exchange component and the pressure storage component respectively store elastic potential energy for absorbing tumor cells and air pressure for pushing out tumor cells; a solenoid valve (11) for controlling the connection state between the thrust cylinder (7) and each component is provided on the side wall of the thrust chamber (7); and the solenoid valve (11) is connected to a control system signal.

2. The tumor detection sampling and inspection device according to claim 1, characterized in that: The driving assembly comprises a driving groove (12) provided on the connecting seat (4), a servo motor (13) being fixedly connected in the driving groove (12), a threaded rod (14) being coaxially fixedly connected to the output shaft of the servo motor (13), an end of the threaded rod (14) away from the connecting seat (4) passing through the top wall of the thrust cylinder (3) and extending into the compression chamber (8), a connecting cylinder (15) being fixedly connected to the bottom wall of the connecting seat (4), an end of the threaded rod (14) close to the connecting seat (4) being rotatably connected to the bottom end of the connecting cylinder (15), a ball nut (16) being located at the penetration point of the threaded rod (14) being provided on the top wall of the thrust cylinder (3), an outer wall of the ball nut (16) being fixedly connected to the thrust cylinder (3), and the thrust cylinder (3) being threadably connected to the threaded rod (14) through the ball nut (16).

3. The tumor detection sampling and inspection device according to claim 2, characterized in that: The bottom end of the threaded rod (14) is fixedly connected to a limiting block (17).

4. The tumor inspection sampling and delivery device according to claim 3, characterized in that: The air pressure exchange component comprises a sealing ring (19) connected to a first air pipe (10), the sealing ring (19) being sleeved on the middle part of the outer wall of the thrust cylinder (3), a piston (20) being arranged inside the sealing ring (19), the piston (20) being slidably matched with the inner wall of the sealing ring (19), the piston (20) dividing the chamber inside the sealing ring (19) into a first chamber (1901) and a second chamber (1902) from top to bottom, the connection point between the first air pipe (10) and the sealing ring (19) being located in the first chamber (1901), the bottom wall of the second chamber (1902) being connected to a second air pipe (21), and the end of the second air pipe (21) away from the second chamber (1902) being connected to the pressure storage component.

5. The tumor inspection sampling and delivery device according to claim 4, characterized in that: The pressure storage assembly comprises a pressure storage ring (22) connected to a second air pipe (21). A one-way air valve (23) is arranged in the second air pipe (21). The one-way air valve (23) allows gas to flow from the second chamber (1902) to the pressure storage ring (22). The pressure storage ring (22) is also sleeved on the outside of the thrust cylinder (3) and is located below the sealing ring (19). A plurality of first springs (24) are arranged in the pressure storage ring (22). Both ends of the first springs (24) are respectively fixedly connected to the inner top wall and the inner bottom wall of the pressure storage ring (22). A side wall of the pressure storage ring (22) close to the thrust cylinder (3) is connected to a third air pipe (25). The end of the third air pipe (25) away from the pressure storage ring (22) penetrates through the side walls of the thrust cylinder (3) and the fixed cylinder (5) and extends into the push-pull cavity (7). The connection state of the third air pipe (25) is controlled by the solenoid valve (11).

6. The tumor inspection sampling and delivery device according to claim 5, characterized in that: A plurality of second springs (26) are arranged in the second chamber (1902), and the two ends of the second springs (26) are fixedly connected to the bottom wall of the piston (20) and the inner bottom wall of the sealing ring (19) respectively. The side wall of the second chamber (1902) close to the thrust cylinder (3) is also connected to a fourth air pipe (27), and the end of the fourth air pipe (27) away from the second chamber (1902) is also connected to the push-pull chamber (7). The connection state of the fourth air pipe (27) is controlled by the electromagnetic valve (11).

7. The tumor detection sampling and delivery device according to claim 6, characterized in that: A third spring (28) is arranged in the push-pull cavity (7), and two ends of the third spring (28) are respectively fixedly connected to the inner top wall of the fixed cylinder (5) and the top wall of the sampling displacement block (6).

8. The tumor inspection sampling and delivery device according to claim 7, characterized in that: A buffer layer (29) is fixedly connected inside the positioning shell (1), and a temperature sensor connected to a control system signal is also fixedly connected inside the positioning shell (1).

9. The tumor inspection sampling and delivery device according to claim 8, characterized in that: An ultrasonic probe (18) connected to a control system signal is detachably connected to the bottom end of the positioning shell (1).

10. The tumor inspection sampling and delivery device according to claim 9, characterized in that: The control system includes an ultrasonic image feedback unit, a depth preset and control unit, a gas valve drive module and a test temperature monitoring module; An ultrasonic image feedback unit, used for receiving signals transmitted by the ultrasonic probe (18), and converting these signals into digital data to generate a two-dimensional image of the sampling needle under the patient's skin; A depth preset and control unit, used to receive a preset insertion depth value input by a medical staff through an operation interface, convert and calculate it into a driving power of a servo motor (13), and send a corresponding control signal to the servo motor (13); The air valve driving module is used to receive instructions from the depth preset and control unit, and when the sampling needle reaches the target sampling depth, sends a driving signal to the electromagnetic valve (11) to control the connection with the fourth airway (27), and when it is necessary to remove tumor cells, sends a driving signal to control the electromagnetic valve (11) to connect with the third airway (25); The sample delivery temperature monitoring module is used to receive the temperature signal collected by the temperature sensor, monitor the temperature inside the positioning shell (1), and monitor the sample delivery environment temperature within 18-25° C. When the temperature exceeds the preset range, the sample delivery temperature monitoring module triggers an alarm to notify medical staff.

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