Cosmetic composition for improving skin condition containing wink body of magrice stains and
By performing specific treatment of Magli lees and beer lees, an efficient mixed extract is prepared, and a cosmetic composition for improving skin condition is solved, and the problem of low extraction efficiency of lees in the prior art is achieved, excellent moisturizing and itching reduction effects are achieved, and production costs are reduced.
Patent Information
- Application Number
- CN202410080023.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2023-12-04
- Filing Date
- 2024-01-19
- Publication Date
- 2025-06-06
AI Technical Summary
The prior art is difficult to effectively utilize useful ingredients in wine lees, resulting in low extraction efficiency and environmental pollution when it is developed as a product.
Magli lees and beer lees are processed by specific steps, including drying, grinding, mixing, impregnation, cooling, ultrasonication, fermentation and filtration, to prepare efficient mixed extracts for use in cosmetic compositions.
The excellent moisturizing effect of cosmetic compositions when applied to the human body and itching effect is achieved, which improves the skin condition, while recycling waste resources and reducing production costs.
Abstract
Description
Technical Field
[0001] A cosmetic composition for improving body skin condition containing Makgeolli lees and beer lees and a method for producing the same. Background Art
[0002] The skin protects the body's organs from external stimuli such as temperature and humidity changes, UV rays, and pollutants, and acts as a barrier to prevent the evaporation of water within the skin.
[0003] Skin ages gradually. Internal factors of skin aging include genetic mutations and tissue changes, and external factors include the effects of ultraviolet rays and humidity. As you age, dry skin or weakened immunity may cause itching. This itch robs you of the serenity of daily life, especially if you are an elderly person living alone, and it can be a depressive turn, just like not having someone to scratch your back.
[0004] At the same time, recent awareness of the harmful effects of synthetic chemicals and increased interest in sustainability and ethical consumption are increasing demand for the product.
[0005] TechCi Research is an international market research company headquartered in Burnaby, British Columbia, Canada. TechSci Research - The global organic cosmetics market is growing due to the growing demand for chemical-free personal care products and the changing lifestyles of consumers associated with organic care. The growth is expected to continue, and the eco-friendly (organic) body products market will increase from $9.83 billion in 2021 and $10.49 billion in 2022 to $21.16 billion in 2030 during the forecast period 2023-2030. The CAGR is expected to be 8.9%.
[0006] Wine lees refers to the residue left after filtering alcohol, adding water, and squeezing out the mother liquor. Wine lees, alcohol, runners, residence, it is also called alcoholic beverage.
[0007] Sake is usually disposed of, which may cause environmental pollution and disputes between local residents due to land reclamation, etc. However, since sake lees contain ingredients that are useful to the human body, it is necessary to give these waste resources different values (Re-value).
[0008] There have been various attempts to utilize distiller's grains in the past, but there are limitations in the extraction of useful components for extracts prepared from distiller's grains, and for this reason it remains difficult to find products developed using distiller's grains as the main raw material.
[0009] Therefore, by recycling the waste resource of sake lees, we can provide environmentally friendly and affordable products and reduce production costs. Creative reuse (upcycling) is very important for effectively extracting various components contained in sake lees and transforming them into new high-value-added products rich in ingredients useful to the human body. Summary of the invention
[0010] Problems to be solved by the invention
[0011] The present inventors recognized the problems of the prior art and found that a cosmetic composition containing a mixed extract of Makgeolli lees and beer lees extracted by a method including specific steps exhibits excellent moisturizing effect and itching reduction effect when applied to the human body. After confirming that it has the effect of improving skin conditions, the present invention was completed.
[0012] The present invention relates to a cosmetic composition for improving skin conditions, comprising a mixed extract of Makgeolli lees and beer lees, wherein the Makgeolli lees and beer lees extract are prepared by a method comprising the following steps.
[0013] S1) drying, grinding and mixing Makgeolli wine lees and beer lees;
[0014] S2) immersing the mixture in an aqueous solution of citric acid;
[0015] S3) cooling the immersed mixture;
[0016] S4) subjecting the cooled mixture to ultrasonic treatment;
[0017] S5) adding the bacterial strain to the ultrasonically treated mixture and fermenting;
[0018] S6) preparing an extract from the fermentation mixture; and
[0019] S7) Filter and concentrate the extract.
[0020] The present invention relates to a method for preparing a cosmetic composition for improving skin condition.
[0021] Methods used to solve problems
[0022] The following is explained in detail. All combinations of various components disclosed herein fall within the scope of the present invention. In addition, the scope of the present invention cannot be considered to be limited by the following specific description.
[0023] In addition, unless otherwise defined in the specification, all terms used in the specification should be understood to have the same meaning as commonly understood by those skilled in the art to which the present invention belongs.
[0024] In addition, a singular expression includes a plural expression unless the context clearly dictates otherwise.
[0025] In this specification, terms such as first and second may be used to distinguish or describe one component from another component, but the components should not be interpreted as being limited by these terms. For example, within the scope of the present invention, a first component may be named a second component, and vice versa.
[0026] In addition, in this specification, "degree" combined with a number represents Celsius (°C) and can be used interchangeably with "°C" (for example, "100 degrees" has the same meaning as "100°C").
[0027] The present invention provides a cosmetic composition for improving skin conditions, comprising a mixed extract of Makgeolli lees and beer lees.
[0028] In the present invention, "Makgeolli" is a Korean traditional liquor, Takju, density, skill, Huizhou, it is also called Baizhou. According to an embodiment of the present invention, it is preferred that Makgeolli is rice Makgeolli fermented by adding yeast to rice, but is not limited thereto.
[0029] In the present invention, "beer" refers to fermented malt made from grains, and refers to beer flavored with hops, a flavoring, as a main ingredient.
[0030] In the present invention, "sake" is the residue left after filtering alcohol and squeezing out the mother liquor and adding water to the residue, also known as sake lees, sake lees, sake lees, liquor, ethanol gourd, etc. Sake contains starch, in addition to protein, fiber, minerals, vitamins, enzymes, and it is well known that it contains a variety of nutrients, including yeast.
[0031] In the present invention, "mixed extract" refers to an extract prepared from a mixture of raw materials rather than from each raw material.
[0032] In the present invention, "extract" refers to the result of extraction using an appropriate extraction solvent, and the extract is a product obtained by extraction. It includes the extract itself and all preparations of the extract that can be formed using the extract, such as an extract, a diluted or concentrated extract, a dry product obtained by drying the extract, a crude product or purified product thereof, a fraction or a mixture thereof.
[0033] The extract of the present invention can be prepared and used in the form of dry powder after extraction, but is not limited thereto.
[0034] In the present invention, the extract can be prepared by an extraction method commonly used in the art, for example, boiling water extraction, hot water extraction, cold needle extraction, reflux cooling extraction, ultrasonic extraction, high temperature and high pressure extraction, and the like.
[0035] When preparing the extract of the present invention, water is used as the extraction solvent; lower alcohols having 1 to 4 carbon atoms such as methanol, ethanol, propanol, butanol; polyols such as glycerol, butylene glycol, propylene glycol; hydrocarbon solvents such as chloroform, methyl acetate, ethyl acetate, benzene, hexane, ether, petroleum ether, dichloromethane; or a mixture thereof can be used, but is not limited thereto.
[0036] In the present invention, the mixed extract of Makgeolli lees and beer lees can be prepared by a method comprising the following steps:
[0037] S1) drying, grinding and mixing Makgeolli wine lees and beer lees;
[0038] S2) immersing the mixture in an aqueous solution of citric acid;
[0039] S3) cooling the immersed mixture;
[0040] S4) subjecting the cooled mixture to ultrasonic treatment;
[0041] S5) adding the bacterial strain to the ultrasonically treated mixture and fermenting;
[0042] S6) preparing an extract from the fermentation mixture; and
[0043] S7) Filter and concentrate the extract.
[0044] In the present invention, the stages S1 to S4 are pretreatment stages before fermentation, which are used to increase the activity of useful components contained in Makgeolli lees and beer lees, in order to obtain an extract with a high extraction rate in the subsequent fermentation process.
[0045] The drying steps of Makgeolli lees and beer lees in S1 above include hot air drying, freeze drying, and any other known method such as room temperature drying. According to one embodiment of the present invention, room temperature drying may be required, but it is not limited thereto.
[0046] The grinding at the above stage S1 is intended to ensure that the subsequent stages have a larger surface area so that reactions or extractions can easily occur. This can be done by known methods.
[0047] According to the above steps S1, Makgeolli lees and beer lees can be mixed in a weight ratio of 2-1:1. According to one embodiment of the present invention, Makgeolli lees and beer lees can be mixed in a weight ratio of 1:1, but it is not limited thereto.
[0048] According to the above steps S2, the concentration of the citric acid aqueous solution can be 0.01% to 1% (v / v), preferably 0.01% to 0.3% (v / v), but not limited thereto. In addition, according to one embodiment of the present invention, the concentration of the citric acid aqueous solution is preferably 0.05% (v / v), but not limited thereto.
[0049] According to the above steps S2, 100 to 500 parts by weight of citric acid aqueous solution can be added based on 100 parts by weight of the mixture of Makgeolli lees and beer lees. According to one embodiment of the present invention, the added amount can be 200 to 400 parts by weight or 150 to 350 parts by weight based on 100 parts by weight of the mixture of Makgeolli lees and beer lees, but is not limited thereto.
[0050] According to the steps above S2, according to one embodiment of the present invention, the immersion using the citric acid aqueous solution can be performed at a temperature of 50 to 80° C. for 1 to 10 minutes, but is not limited thereto.
[0051] In the above steps S3, cooling may be to a temperature of 15 to 25°C, preferably, the temperature may be lowered to 20 to 25°C, but is not limited thereto.
[0052] According to the steps above S4, the ultrasonic wave can be a low-frequency ultrasonic wave, and the low frequency can be a frequency of 5 to 30 kHz. According to one embodiment of the present invention, the frequency can be 23 kHz, but it is not limited thereto.
[0053] According to the steps above S4, the ultrasonic irradiation time can be 3 to 7 hours. According to one embodiment of the present invention, the ultrasonic irradiation time can be 4 to 6 hours, but is not limited thereto.
[0054] According to one embodiment of the present invention, after S4 performs the following steps: S5 may further include the step of maturing the mixture of pretreated Makgeolli lees and beer lees at low temperature before performing this step. The maturation may be performed at a temperature of 1 to 5°C for 5 to 15 hours, but is not limited thereto.
[0055] In the present invention, step S5 is a step of fermenting the pre-treated Makgeolli lees and beer lees.
[0056] The strain used in the above step S5 can be lactic acid bacteria, specifically, it can be lactic acid bacteria, more specifically, lactic acid bacteria sakei (Lactobacillus sakei), Lactobacillus brevis or the lactobacillus may be Lactobacillus plantarum. According to one embodiment of the present invention, the lactic acid bacteria is lactic acid bacteria and it may be the short form (L.brevis), but it is not limited to this.
[0057] S6 is the step of extracting from the fermentation mixture. According to one embodiment of the present invention, the extraction can be carried out by a method comprising the following steps:
[0058] S6-1) subjecting the fermentation mixture to primary extraction at a temperature of 45 to 60° C.; and
[0059] S6-2) Ethanol is added to the primary extraction mixture, and a secondary extraction is performed at a temperature of 45 to 60°C.
[0060] According to an embodiment of the present invention, steps S6 - 1 and S6 - 2 may be performed for 1 to 5 hours, preferably, for 1 to 3 hours, but are not limited thereto.
[0061] According to an embodiment of the present invention, in step S6-2, the concentration of ethanol may be 60% (v / v); and in step S5, the amount added may be 30% of the volume of the result obtained in this step, but is not limited thereto.
[0062] The above step S7 is to finally filter the extract. In the process of focusing, filtering and concentrating can be carried out using conventional methods in the art, which are not limited.
[0063] According to one embodiment of the present invention, the step S7 or above may further include a freeze-drying step, but is not limited thereto.
[0064] In the present invention, the mixed extract of Makgeolli lees and beer lees is used as a cosmetic. Its content may be 0.1 to 20% by weight, preferably 1 to 10% by weight, more preferably 3 to 7% by weight, based on the total weight of the composition, but is not limited thereto.
[0065] In the present invention, the cosmetic composition can be used for body use. In the present invention, "for body use" means use on parts other than the face. This means the intended use.
[0066] In the present invention, "improvement of skin condition" refers to improvement of skin moisture content, itchy comfort, inflammation comfort and it may show more than one effect of improving skin color, but according to one embodiment of the present invention, it can improve skin moisture and relieve itching, but is not limited to this.
[0067] The ingredients contained in the cosmetic composition of the present invention may include ingredients commonly used in cosmetic compositions, such as preservatives, antioxidants, stabilizers, solubilizers, vitamins, conventional adjuvants such as pigments and fragrances, and carriers.
[0068] In the present invention, the composition may further contain a preservative. Preservatives are, for example, parabens, alcohols (an alcohol), organic acids and salts thereof; examples include isothiazole compounds, urea and triclosan, but are not limited thereto.
[0069] The cosmetic composition of the present invention includes, for example, solutions, suspensions, emulsions, pastes, gels, powders, creams, lotions, washes, which can be formulated into water-soluble liquids, essences, cleansers containing surfactants, oils, foundations, emulsion foundations, wax foundations, sprays, shampoos, conditioners, shower gels, soaps, etc., but is not limited to these. No, it can be produced in any formulation form commonly used in the cosmetics industry.
[0070] When the cosmetic composition of the present invention is formulated into a paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivatives, polyethylene glycol, silicone resin, bentonite, silicon dioxide, talc or zinc oxide can be used as a carrier component.
[0071] When the cosmetic composition of the present invention is formulated into a powder or spray, lactose, talc, silicon dioxide, aluminum hydroxide, calcium silicate or polyamide powder can be used as a carrier component. Especially in the case of spray, chlorofluorocarbons may also contain propellants such as hydrocarbons, propane / butane or dimethyl ether.
[0072] When the cosmetic composition of the present invention is formulated as a solution or emulsion, a solvent, solubilizer or emulsifier is used as a carrier component, such as water, ethanol, isopropyl alcohol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3-butylene glycol oil, aliphatic glycerol. It may include esters of sorbitan, polyethylene glycol or fatty acid esters.
[0073] When the cosmetic composition of the present invention is formulated as a suspension, a liquid diluent such as water, ethanol or propylene glycol is used as a carrier component, ethoxylated isostearyl alcohol, polyoxyethylene sorbitan esters and polyoxyethylene sorbitan esters may use a suspending agent, microcrystalline cellulose, aluminum metahydroxide, bentonite, agar or tracant.
[0074] When the cosmetic composition of the present invention is formulated as a surfactant-containing cleanser, as carrier components, fatty alcohol sulfates, fatty alcohol ether sulfates and sulfosuccinic acid, monoesters, isethionates, imidazolinium derivatives, taurine methyl esters, sarcosinates, fatty acid amide ether sulfates, alkylamide betaines, fatty alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glyceryl fatty acid esters can be used.
[0075] Ingredients other than the above-mentioned various moisturizing ingredients can be appropriately selected and mixed by those skilled in the art without difficulty according to the formulation or the purpose of use.
[0076] Another aspect of the present invention is a method for preparing a cosmetic composition comprising the steps of:
[0077] M1) preparing a mixed extract of Makgeolli wine lees and beer lees; and
[0078] M2) The mixed extract of Makgeolli lees and beer lees prepared above is mixed to 0.1% to 20% by weight of the total composition.
[0079] In the present invention, the mixed extract of Makgeolli lees and beer lees is used as a cosmetic. It can be mixed in a ratio of 0.1 to 20 weight %, preferably 1 to 10 weight %, more preferably 3 to 7 weight %, based on the total weight of the composition, but is not limited thereto.
[0080] In the present invention, the mixed extraction of Makgeolli lees and beer lees can be prepared by a method comprising the following steps:
[0081] S1) drying, grinding and mixing Makgeolli wine lees and beer lees;
[0082] S2) immersing the mixture in an aqueous solution of citric acid;
[0083] S3) cooling the immersed mixture;
[0084] S4) subjecting the cooled mixture to ultrasonic treatment;
[0085] S5) adding the bacterial strain to the ultrasonically treated mixture and fermenting;
[0086] S6) preparing an extract from the fermentation mixture; and
[0087] S7) Filter and concentrate the extract.
[0088] In this specification, unless otherwise specified, specific details related to the method for manufacturing the cosmetic composition are provided. The application described in the cosmetic composition is substantially the same and is omitted to avoid unnecessary repetition.
[0089] Effects of the Invention
[0090] The cosmetic composition for improving body skin condition of the present invention exhibits excellent moisturizing effect and itching reducing effect when applied to the human body, and can be effectively used to improve skin condition.
[0091] The cosmetic composition for improving the skin condition of the body of the present invention recycles the discarded waste resource lees, and can produce environmentally friendly and price-favorable products by reducing production costs.
[0092] Effects obtainable from the embodiments are not limited to the above-mentioned effects, and other effects not mentioned can be clearly derived and understood by those skilled in the art based on the following detailed description. DETAILED DESCRIPTION
[0093] The present invention is described in more detail below by embodiment. However, these embodiments are only for illustrative purposes, and the scope of the present invention is not limited to these embodiments. Also, unless otherwise clearly stated, each component or feature can be considered as optional. Each component or feature can be realized in a form that is not combined with other components or features. In addition, various embodiments can be configured by combining some components and / or features. Some features or characteristics of an embodiment can be included in another embodiment or can be replaced by the corresponding features or characteristics of another embodiment. In addition, the terms that are not specifically defined in this specification should be understood to have the meaning commonly used in the technical field to which the present invention belongs.
[0094] Example
[0095] First, Makgeolli (main ingredient: rice), sake lees, and beer (main ingredient: malt) lees are completely dried using a room temperature dryer and then finely ground.
[0096] Then, the crushed Makgeolli lees and beer lees are mixed evenly at a weight ratio of about 1:1.
[0097] About 3 times by weight of a 0.05% (w / v) citric acid aqueous solution is added to the ground lees mixture and allowed to stand (soak) at a temperature of 50 to 80° C. for about 5 minutes.
[0098] Next, the soaked ground beef mixture was cooled to 20 to 25° C., and while maintaining the temperature, ultrasonic waves (frequency: 23 kHz) were irradiated for about 5 hours using an ultrasonic device. At this time, the container was constantly stirred.
[0099] Then, the sonicated mixture was cooled to a temperature of 1 to 5° C. and aged for about 10 hours while maintaining the temperature.
[0100] Then, lactobacillus (a type of lactic acid bacteria) was added to the ultrasonically treated mixture. Lactobacillus brevis was added and fermented. Specifically, the lactobacillus was cultured in MRS broth for 20 hours. Brevis B3-18 (Lactobacillus brevis B3-18) was inoculated to 10 8 cfu / g and cultured at 27°C for 24 hours.
[0101] Next, the fermented lees mixture was stirred at 50±5°C for about 2 hours for primary extraction, and 60% (v / v) ethanol was added to 30% ethanol equivalent to the volume of the content. Then, it was added to a container, stirred for about 2 hours, and secondary extraction was performed, filtered, and concentrated under reduced pressure. The extract was freeze-dried to obtain the extract.
[0102] Next, 5.00% of the extract prepared above, the cosmetic composition of Example 1 was prepared with the remaining amounts of propylene glycol 6.00%, glycerin 5.00%, betaine 0.50%, polyglyceryl-10 laurate 0.40%, carbomer 0.35%, arginine 0.30%, butylene glycol 0.5% and purified water.
[0103] Comparative Example
[0104] First, Makgeolli lees and beer lees are completely dried using a room temperature dryer and then finely ground.
[0105] Then, the crushed Makgeolli lees and beer lees are mixed evenly at a weight ratio of about 1:1.
[0106] Next, Lactobacillus brevis was added to the lactic acid bacteria in the mixture and fermented. Specifically, the lactic acid bacteria were cultured in MRS broth for 18 hours. Brevis B3-18 (Lactobacillus brevis B3-18) was inoculated to 10 8 cfu / g and cultured at 27°C for 24 hours.
[0107] Next, the fermented sake lees mixture was stirred at a temperature of 50±5° C. for about 4 hours for extraction, and then filtered and concentrated to obtain an extract.
[0108] Next, 5.00% of the extract prepared above, 6.00% of propylene glycol, 5.00% of glycerol, 0.50% of betaine, 0.40% of polyglyceryl-10 laurate, 0.35% of carbomer, 0.30% of arginine, 0.5% of butylene glycol, and the balance of purified water were used to prepare the cosmetic composition of 1.
[0109] Experimental example
[0110] 1. Criteria for selecting test subjects
[0111] 1) A person who voluntarily writes and signs a consent form after receiving a detailed explanation of the matters that the test subject should be informed by the test leader or a person entrusted by the test leader.
[0112] 2) People who experience itching due to dryness of the test site
[0113] 3) Adult men and women aged 65 and above (n=20), healthy people with no acute or chronic physical diseases, including skin diseases
[0114] 4) People who can be tracked during the test
[0115] 2. Exclusion criteria
[0116] 1) Pregnant or breastfeeding women or women who may become pregnant
[0117] 2) People who have used topical skin preparations containing steroids to treat skin diseases for more than 1 month
[0118] 3) Those who have taken the same test within 6 months
[0119] 4) People with sensitive skin or allergies
[0120] 5) People with skin abnormalities such as moles, acne, erythema, telangiectasia, etc. in the test area
[0121] 6) Those who have undergone surgery in the trial area within 6 months before the start of the study
[0122] 7) Other persons who the examination administrator deems unsuitable to take the examination
[0123] 3. Withdrawal criteria
[0124] 1) If adverse reactions such as itching and erythema occur at the test site
[0125] 2) If the test subject has problems with the result evaluation due to excessive exposure to ultraviolet rays in the test area, excessive drinking, smoking, etc.
[0126] 3) It is difficult to follow up during the self-examination due to personal circumstances
[0127] 4) If the subject violates the usage method or schedule without special reasons
[0128] 4. Test Methods
[0129] It is a device that indirectly measures moisture content by using the property that skin capacitance increases in proportion to moisture content. The measurement unit is expressed in arbitrary units (AU), which is a relative, arbitrary value of skin moisture content.
[0130] The test subjects washed their upper arms with the same body cleanser, patted the water off with a paper towel, and stabilized them in a constant temperature and humidity chamber (temperature: 22±2°C, humidity: 50±5%) for 30 minutes. The keratometer was used to perform 5 measurements each time, and the average value was used as the measured value.
[0131] The test subjects were educated on precautions and methods of use, composition distribution of Examples (n=10) and Comparative Examples (n=10), and the test subjects were tested every morning and evening for 4 weeks. It was to be used twice.
[0132] Instrumental measurements were taken on the same area before application of the test substance, immediately after one application, 2 weeks after application and 4 weeks after application.
[0133] 5. Test results (1)
[0134] The test results of the effect related to improving skin moisture are shown in the following table.
[0135]
Table 1
[0136] distribute Before use Immediately after one use After 2 weeks of use After 4 weeks of use example 35.23±5.11 53.33±5.10 55.12±5.27 57.12±5.11 Comparative Example 35.25±5.10 45.72±6.06 47.26±5.45 48.03±5.27
[0137] From the above results, it can be seen that compared with before using the test substance, the skin moisture content increased by 51.38% after 1 use, the skin moisture content increased by 56.46% after 2 weeks of use, and the skin moisture content increased by 62.13% after 4 weeks of use.
[0138] In contrast, in the case of the comparative example, the moisture content increased by 29.70% immediately after one use, increased by 34.07% after two weeks of use, and increased by 36.26% after four weeks of use.
[0139] The above results confirm that the cosmetic composition of the present invention can exhibit excellent moisturizing effect. It can also be confirmed that a better moisturizing effect can be obtained in the production of the extract compared with the comparative example in which some steps are omitted.
[0140] 8. Test results (2)
[0141] Pruritus relief assessment (itch sensation assessment) was performed on subjects at visits before, 2 weeks after, and 4 weeks after the test.
[0142] The evaluation criteria were divided into 0 to 4 points according to the degree of itching, as shown in Table 2 below.
[0143] <Evaluation Criteria>
[0144] 4: Itching is very severe
[0145] 3: Severe itching
[0146] 2: Severe itching.
[0147] 1: A little itchy
[0148] 0: No itching
[0149]
Table 2
[0150] distribute Before use After 2 weeks of use After 4 weeks of use example 2.21 1.12 0.09
[0151] It can be seen from the above results that the average value of the itch relief degree of the subjects decreased significantly compared with that before use, confirming that the composition of the present invention can have a significant improvement effect on itch when applied to the skin. Skin.
[0152] The various embodiments described above may be implemented in other specific forms without departing from the technical ideas and basic features. Therefore, the above detailed description should not be interpreted as being restrictive in all aspects, but should be regarded as illustrative. The scope of each embodiment should be determined by a reasonable interpretation of the attached claims, and all changes within the equivalent range of each embodiment are included in the scope of each embodiment. In addition, claims that do not have a clear reference relationship in the patent claims can be combined to form an embodiment, or included as a new claim through post-submission amendments.
Claims
1. A cosmetic composition for improving skin condition, wherein: The cosmetic composition for improving skin condition comprises a mixed extract of Makgeolli lees and beer lees, and the preparation method of the Makgeolli lees and beer lees extract comprises the following steps: S1) drying, grinding and mixing Makgeolli wine lees and beer lees; S2) immersing the mixture in an aqueous solution of citric acid; S3) cooling the immersed mixture; S4) subjecting the cooled mixture to ultrasonic treatment; S5) adding the bacterial strain to the ultrasonically treated mixture and fermenting; S6) preparing an extract from the fermentation mixture; and S7) Filter and concentrate the extract.
2. The cosmetic composition for improving skin condition according to claim 1, wherein: In step S1, Makgeolli lees and beer lees are mixed in a weight ratio of 1:1 to prepare a cosmetic for improving skin conditions.
3. The cosmetic composition for improving skin condition according to claim 1, wherein: In step S2, the citric acid aqueous solution is a cosmetic for improving skin conditions, and its concentration is 0.01-1% (v / v).
4. The cosmetic composition for improving skin condition according to claim 1, wherein: The ultrasonic wave in step S4 is performed at a frequency of 5 to 30 kHz for 3 to 7 hours.
5. The cosmetic composition for improving skin condition according to claim 1, wherein: In step S6, the extract is produced by a method comprising the following steps: S6-1) subjecting the fermentation mixture to primary extraction at a temperature of 45 to 60° C.; and S6-2) Ethanol is added to the primary extraction mixture, and a secondary extraction is performed at a temperature of 45 to 60°C.