Traditional Chinese medicine patch for conditioning qi depression constitution and preparation method of traditional Chinese medicine patch

Abstract

The invention relates to a traditional Chinese medicine patch for conditioning qi depression constitution and a preparation method thereof. The traditional Chinese medicine patch is prepared from multiple traditional Chinese medicines such as cortex albiziae, pericarpium citri reticulatae and ligusticum wallichii according to a specific ratio through raw material pretreatment, drying, grinding, mixing and stirring and packaging. The preparation process is scientific and can effectively retain active ingredients of the medicinal materials. The traditional Chinese medicine composition has the effects of soothing liver and regulating qi, and can be used for preparing medicines for treating various qi depression related diseases such as depression, anxiety, insomnia and the like. During use, 2-6 patches are applied to corresponding acupuncture points for about 6 hours every day, a course of treatment lasts for 5 days, and pungency is avoided to stimulate food and wine during the course of treatment. Clinical cases show that the traditional Chinese medicine composition can obviously improve symptoms such as impatience and poor sleep caused by qi depression constitution. The traditional Chinese medicine patch adopts an external application mode, is convenient to use and high in safety, avoids the defects of oral medicines, provides a new conditioning choice for people with qi depression constitution, and has a wide application prospect.

Description

Technical Field

[0001] The present invention relates to the technical field of Chinese medicine patches, and in particular to a Chinese medicine patch for regulating qi stagnation constitution and a preparation method thereof. Background Art

[0002] In the theory of constitution in traditional Chinese medicine, Qi-stagnation constitution is a relatively common type of biased constitution. According to relevant surveys and studies, the proportion of people with Qi-stagnation constitution in the population is about 10%-15%, and with the accelerated pace of life in modern society and the increase in competitive pressure, this proportion has a tendency to gradually increase. People with Qi-stagnation constitution often show a series of discomfort symptoms due to long-term emotional distress and stagnation of Qi. They are depressed, emotionally fragile, and unhappy. Their personalities are often introverted, unstable, sensitive, and suspicious. In terms of the body, they are prone to insomnia, flank pain, and fullness in the stomach. They are also prone to diseases such as zang-fu, plum pit qi, lily disease, and depression. They have poor adaptability to mental stimulation, and their discomfort symptoms may worsen when the environment changes such as rainy weather.

[0003] At present, there are various treatment methods for conditioning qi stagnation constitution and related diseases, but they all have certain limitations. In terms of drug treatment, although Western medicines such as antidepressants and anti-anxiety can relieve symptoms to a certain extent, they are often accompanied by more adverse reactions, such as dizziness, fatigue, nausea, drowsiness, etc. Some drugs are also addictive and dependent. Long-term use may cause damage to liver and kidney function, and patients' compliance is poor. Although Chinese medicine oral decoctions can regulate the body's qi and blood and viscera functions as a whole, they take a lot of time to boil and taste bitter. Many patients find it difficult to persist in taking them, especially children, the elderly, and people who are sensitive to taste. In addition, the formula adjustment of Chinese medicine decoctions requires professional Chinese medicine practitioners to be carried out according to the specific conditions of the patients, which is not convenient for patients.

[0004] In terms of psychological treatment, psychological counseling and psychotherapy can help with the psychological problems associated with Qi stagnation, but they require long-term, systematic intervention by professional psychological counselors or psychotherapists, which is expensive, and resources are unevenly distributed, making it difficult for many regions to obtain high-quality psychological treatment services. At the same time, psychotherapy alone has limited effect on some patients with Qi stagnation who have developed serious organic diseases, such as thyroid nodules and breast hyperplasia.

[0005] In terms of lifestyle intervention, exercise and dietary adjustment can improve Qi stagnation constitution to a certain extent, but these methods are relatively slow in effect and require long-term persistence by patients. For patients with more severe symptoms, it is difficult to relieve symptoms in a short period of time. Moreover, many patients are unable to effectively adhere to a healthy lifestyle due to busy work and difficulty in changing their living habits.

[0006] Most of the topical products available on the market are for the treatment of a single symptom, such as sleep aids for insomnia and pain relief patches for pain relief. There are relatively few topical patches specifically used to regulate qi stagnation constitution. Moreover, the formulations of these patches may not be scientific enough to effectively regulate the various symptoms of qi stagnation constitution. At the same time, some products have deficiencies in production technology and material selection, which may lead to slow drug release, poor absorption, or cause adverse reactions such as skin allergies.

[0007] In summary, it is urgent to develop a safe, effective, convenient and accurate product for regulating qi stagnation. The Chinese medicine patch for regulating qi stagnation is proposed based on solving the above problems, aiming to provide a more effective conditioning method for people with qi stagnation. Summary of the invention

[0008] The purpose of the present invention is to solve the shortcomings of the prior art, and to propose a Chinese medicine patch for regulating qi stagnation constitution. The drug composition of the Chinese medicine patch includes, by weight: 6g of Albizzia julibrissin peel, 4g of tangerine peel, 7g of Chuanxiong, 4g of clove, 6g of rose, 6g of Tribulus terrestris, 6g of mint, and 8g of lemon.

[0009] A method for preparing a Chinese medicine patch for regulating qi stagnation constitution comprises the following steps: S1. Raw material pretreatment: Select high-quality, mildew-free and impurity-free albizzia peel, tangerine peel, chuanxiong, cloves, rose, tribulus terrestris, mint and lemon. Wash and dry tangerine peel and lemon, and remove impurities from other medicinal materials; S2. Drying treatment: Place the pretreated raw materials in a drying device and dry them at 40-50°C for 5-8 hours to reduce the moisture content of the raw materials to less than 8%, which is convenient for subsequent grinding; S3, initial grinding: put the dried raw materials into a common grinder for initial grinding, set the grinding machine speed to 150-200 rpm, control the grinding time to 10-15 minutes, and grind to a particle size of 80-100 mesh; S4, fine grinding: the powder after the initial grinding is transferred to an ultrafine grinding machine, the frequency of the ultrafine grinding machine is set to 20-30 Hz, the grinding time is 20-30 minutes, and further ground to a particle size of 200-300 meshes to increase the surface area of ​​the drug and improve the release rate of the active ingredient; S5, mixing and stirring: pour the finely ground powders of each flavor into a mixing and stirring machine, and stir at a speed of 100-150 rpm for 15-20 minutes to ensure that the powders are fully mixed; S6. Packaging: Put the evenly mixed powder into a non-woven bag that has good air permeability and meets hygiene standards, and use an automatic quantitative packaging machine to seal and package the powder according to a certain weight standard for each bag to make a Qi Yu patch.

[0010] Preferably, the drying equipment in step S2 is a vacuum drying oven, and the vacuum degree is controlled at 0.05-0.08 MPa.

[0011] Preferably, in step S3, during the initial grinding process, the grinder is intermittently cooled for 5-10 minutes every 20-30 minutes to prevent the loss of drug components due to heat generated by grinding.

[0012] The invention discloses an application of a Chinese medicine patch for regulating qi stagnation constitution, which is used for treating depression, anxiety, neurosis, obsessive-compulsive disorder, insomnia, irritability, plum pit qi, lily disease, thyroid nodules, menopausal syndrome and breast hyperplasia.

[0013] A method for using a Chinese medicine patch for regulating qi stagnation constitution comprises the following steps: Preparation before use: Clean the skin of the area to be applied with warm water, make sure the skin is clean, dry and free of dirt, oil and sweat, then gently dry it with a soft towel; select acupuncture points that have the effect of soothing the liver and regulating qi for people with qi stagnation, and prepare 2-6 Chinese medicine patches according to personal constitution, severity of symptoms and instructions for use; Application: Open the patch package and carefully take out the patch to avoid spilling the powder. Gently peel off the anti-sticking paper of the patch and align the side with the powder accurately with the determined acupuncture point. Then gently press the edge of the patch to make it fit the skin tightly. Make sure there are no bubbles or wrinkles between the patch and the skin to ensure that the drug can fully contact the skin and promote absorption. Application time control: Apply for about 6 hours each time; during the application period, pay close attention to skin reactions. If you experience discomfort such as itching, tingling, redness, swelling, etc. during the application process, you should remove the patch immediately and wash the application area with clean water. If the symptoms persist or worsen, you need to seek medical attention in time. If there is no discomfort after 6 hours of application, you can remove the patch on time. When removing it, you should peel it off slowly along the direction of the skin to avoid damaging the skin due to excessive force.

[0014] Preferably, the acupoints are Tanzhong, Neiguan, Taichong and Qimen.

[0015] Preferably, the Qi-stagnation constitution is manifested as being mostly thin, depressed, emotionally fragile, irritable, pale red tongue, thin white fur, stringy pulse, introverted and unstable personality, sensitive and suspicious, prone to zang-fu, plum-pit qi, lily disease and depression, etc., poor adaptability to mental stimulation, and inability to adapt to one or more of rainy weather.

[0016] Preferably, the conditioning treatment course is 5 days.

[0017] Preferably, when using the Chinese medicine patch, one needs to avoid certain foods, including alcohol and spicy foods, and the diet needs to be light.

[0018] In the above Chinese medicine patch: Albizzia julibrissin: Traditional medicine believes that Albizzia julibrissin is sweet and mild in nature, enters the heart and liver meridians, and can relieve liver depression and calm the mind. Modern research has found that Albizzia julibrissin contains ingredients such as albizzia glycosides and tannins. Albizzia glycosides have sedative and hypnotic effects, can regulate the function of the nervous system, relieve anxiety and depression, and improve sleep quality. Tannins have certain anti-inflammatory and antioxidant effects, can reduce the body's inflammatory response, protect nerve cells, and help improve problems such as poor mental state caused by qi stagnation.

[0019] Tangerine peel: Tangerine peel is pungent, warm and fragrant. It is traditionally used to regulate qi and dispel cold, relieve stagnation and invigorate the stomach. Its main components include volatile oils and hesperidin. Volatile oils can promote the secretion of digestive juices, enhance gastrointestinal motility, help digestion, improve spleen and stomach function, and relieve gastrointestinal discomfort caused by qi stagnation. Hesperidin has anti-inflammatory, antioxidant, and blood lipid regulating effects. It can regulate the body's internal environment and enhance the body's resistance. It has a positive significance for the conditioning of qi stagnation constitution.

[0020] Chuanxiong: Chuanxiong is pungent and warm in nature, and enters the liver and gallbladder meridians. Traditional medicine uses it to promote qi and blood circulation, relieve depression and relieve pain. Modern pharmacological studies have shown that Chuanxiong contains ingredients such as ligustrazine and ferulic acid. Ligustrazine can dilate blood vessels, improve blood circulation, increase blood supply to the brain, and help relieve symptoms such as headaches and dizziness caused by qi stagnation. Ferulic acid has antioxidant and anti-platelet aggregation effects, can regulate cardiovascular system functions, reduce blood stasis in the body, and improve the poor flow of qi and blood caused by qi stagnation.

[0021] Clove: Clove is pungent, warm and aromatic. In traditional medicine, it is an important medicine for treating stomach cold and hiccups. Its main active ingredients, eugenol and clove oil, have antibacterial, anti-inflammatory and stomachic effects. Eugenol can inhibit the growth of harmful bacteria in the gastrointestinal tract, regulate gastrointestinal function, and relieve symptoms such as stomach discomfort and hiccups. The anti-inflammatory effect can reduce gastrointestinal inflammatory reactions, promote digestion and absorption, and improve digestive system symptoms associated with qi stagnation.

[0022] Rose: Rose is aromatic and can promote qi circulation, and its bitter taste can relieve qi. It is traditionally used to relieve qi depression in the liver and gallbladder, invigorate the spleen and stimulate appetite, and relieve pain. Modern research has found that rose contains volatile oils, flavonoids and other ingredients. Volatile oils have the effects of soothing emotions and anti-depression, can regulate the nervous system, and relieve negative emotions such as anxiety and depression. Flavonoids have antioxidant and anti-inflammatory effects, can protect body cells from oxidative damage, reduce inflammatory reactions, and have an improvement effect on emotional problems and body inflammation caused by qi stagnation constitution.

[0023] Tribulus terrestris: Tribulus terrestris can calm liver yang and has a mild effect. It contains steroidal saponins, flavonoids and other ingredients. Steroidal saponins have immune regulation and anti-inflammatory effects, can enhance the body's immunity and reduce inflammatory reactions. Flavonoids have antioxidant and anti-allergic effects, can scavenge free radicals, reduce allergic symptoms, and have a certain effect on alleviating mood swings and skin discomfort caused by qi stagnation.

[0024] Mint: Mint is spicy and fragrant, and enters the liver meridian. Traditional medicine uses it to regulate liver qi and relieve stagnation. Mint contains volatile oils, the main components of which are menthol and menthone. These volatile oils have cooling, analgesic, and anti-inflammatory effects, can stimulate nerve endings, produce a cooling sensation, and relieve symptoms such as headaches and dizziness. At the same time, mint volatile oil can also promote the secretion of digestive juices, enhance digestive function, and improve indigestion caused by qi stagnation.

[0025] Lemon: In traditional medicine, lemon has the effects of promoting qi, harmonizing the stomach, and relieving pain. Lemon is rich in vitamin C, limonene and other ingredients. Vitamin C has antioxidant and immune-enhancing effects, can promote collagen synthesis, and protect body cells. Limonene has the effects of regulating qi and harmonizing the stomach, can regulate gastrointestinal function, relieve stomach pain, bloating and other discomfort symptoms, and is helpful for regulating qi stagnation constitution.

[0026] Compared with the prior art, the present invention has the following beneficial effects: Significant conditioning effect: The Chinese medicine patch in this application has a scientific formula. The synergistic effect of multiple medicinal materials such as julibrissin peel, tangerine peel, and Chuanxiong can effectively soothe the liver and regulate qi, and has a significant conditioning effect on various symptoms and diseases caused by qi stagnation constitution; the julibrissin peel in the formula can relieve liver stagnation and calm the mind; the tangerine peel can regulate qi and dispel cold, and strengthen the stomach; Chuanxiong can promote qi and blood circulation, relieve depression and relieve pain. These medicinal materials are compatible with each other, which can comprehensively regulate human functions and improve qi stagnation constitution.

[0027] Scientific preparation technology: The preparation process covers steps such as raw material pretreatment, drying, grinding, mixing and packaging. Parameters are strictly controlled in each link to retain the effective ingredients of the medicinal materials to the greatest extent, ensuring the quality and stability of the Chinese medicine patch.

[0028] Convenient to use: It adopts the external application method, which avoids the bitterness and gastrointestinal irritation of oral medications and is suitable for all kinds of people. Users can apply it at any time during daily activities according to their own conditions, without complicated operations and professional guidance, which greatly improves the convenience and compliance of conditioning.

[0029] High safety: The medicinal materials used in the Chinese medicine patch, such as julibrissin peel, tangerine peel, and Chuanxiong, are all natural Chinese medicinal materials. While exerting therapeutic effects, they have fewer adverse reactions and less side effects on the human body than chemical synthetic drugs. Long-term use is not likely to cause damage to liver and kidney functions, etc., and it is especially suitable for people with weak constitutions who are not suitable for strong drug stimulation. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 The present invention is a schematic diagram of the production process of a Chinese medicine patch for regulating yang deficiency constitution. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0032] Referring to the figure, this embodiment provides a method for preparing a Chinese medicine patch for regulating qi stagnation constitution, comprising the following steps: S1. Raw material pretreatment: Select high-quality, mildew-free and impurity-free albizzia peel, tangerine peel, chuanxiong, cloves, rose, tribulus terrestris, mint and lemon. Wash and dry tangerine peel and lemon, and remove impurities from other medicinal materials; S2. Drying treatment: Place the pretreated raw materials in a drying device and dry them at 40-50°C for 5-8 hours to reduce the moisture content of the raw materials to less than 8%, which is convenient for subsequent grinding; S3, initial grinding: put the dried raw materials into a common grinder for initial grinding, set the grinding machine speed to 150-200 rpm, control the grinding time to 10-15 minutes, and grind to a particle size of 80-100 mesh; S4, fine grinding: the powder after the initial grinding is transferred to an ultrafine grinding machine, the frequency of the ultrafine grinding machine is set to 20-30 Hz, the grinding time is 20-30 minutes, and further ground to a particle size of 200-300 meshes to increase the surface area of ​​the drug and improve the release rate of the active ingredient; S5, mixing and stirring: pour the finely ground powders of each flavor into a mixing and stirring machine, and stir at a speed of 100-150 rpm for 15-20 minutes to ensure that the powders are fully mixed; S6. Packaging: Put the evenly mixed powder into a non-woven bag that has good air permeability and meets hygiene standards, and use an automatic quantitative packaging machine to seal and package the powder according to a certain weight standard for each bag to make a Qi Yu patch.

[0033] Furthermore, the drying equipment in step S2 is a vacuum drying oven, and the vacuum degree is controlled at 0.05-0.08 MPa.

[0034] Furthermore, in step S3, during the initial grinding process, the grinder is intermittently cooled for 5-10 minutes every 20-30 minutes to prevent the loss of drug components due to heat generated by grinding.

[0035] The invention discloses an application of a Chinese medicine patch for regulating qi stagnation constitution, which is used for treating depression, anxiety, neurosis, obsessive-compulsive disorder, insomnia, irritability, plum pit qi, lily disease, thyroid nodules, menopausal syndrome and breast hyperplasia.

[0036] A method for using a Chinese medicine patch for regulating qi stagnation constitution comprises the following steps: Preparation before use: Clean the skin of the area to be applied with warm water, make sure the skin is clean, dry and free of dirt, oil and sweat, then gently dry it with a soft towel; select acupuncture points that have the effect of soothing the liver and regulating qi for people with qi stagnation, and prepare 2-6 Chinese medicine patches according to personal constitution, severity of symptoms and instructions for use; Application: Open the patch package and carefully take out the patch to avoid spilling the powder. Gently peel off the anti-sticking paper of the patch and align the side with the powder accurately with the determined acupuncture point. Then gently press the edge of the patch to make it fit the skin tightly. Make sure there are no bubbles or wrinkles between the patch and the skin to ensure that the drug can fully contact the skin and promote absorption. Application time control: Apply for about 6 hours each time; during the application period, pay close attention to skin reactions. If you experience discomfort such as itching, tingling, redness, swelling, etc. during the application process, you should remove the patch immediately and wash the application area with clean water. If the symptoms persist or worsen, you need to seek medical attention in time. If there is no discomfort after 6 hours of application, you can remove the patch on time. When removing it, you should peel it off slowly along the direction of the skin to avoid damaging the skin due to excessive force.

[0037] Furthermore, the acupoints are Tanzhong, Neiguan, Taichong and Qimen.

[0038] Furthermore, the Qi-stagnation constitution is manifested as mostly thin body, depressed look, fragile emotions, irritability, pale red tongue, thin white fur, stringy pulse, introverted and unstable personality, sensitivity and suspicion, susceptibility to visceral agitation, plum pit qi, lily disease and depression, poor adaptability to mental stimulation, and inability to adapt to one or more of rainy weather.

[0039] Furthermore, a course of conditioning treatment is 5 days.

[0040] Furthermore, when using the Chinese medicine patch, you need to avoid certain foods, including alcohol and spicy foods, and your diet should be light. The Chinese medicine patch involved in the above embodiment needs to have the following steps in specific clinical applications: ① Preparation of Chinese medicine plaster Raw material pretreatment: Strictly select high-quality, mildew-free, and impurity-free albizzia peel, tangerine peel, chuanxiong, cloves, roses, tribulus terrestris, mint, and lemon. Wash tangerine peel and lemon with clean water, and then place them in a well-ventilated and cool place to dry. Carefully select other medicinal materials and remove residual sand, branches, leaves, and other impurities.

[0041] Drying treatment: Put the pretreated medicinal materials into a vacuum drying oven, set the temperature to 45°C, control the vacuum degree at 0.06MPa, and dry for 6 hours to make the moisture content of the medicinal materials less than 8%. This condition can speed up the drying process while retaining the effective ingredients of the medicinal materials to the greatest extent.

[0042] Initial grinding: Put the dried medicinal materials into a common grinder, set the speed to 180 rpm, grind for 12 minutes, and grind the medicinal materials to a particle size of 90 mesh. During the grinding process, the grinder is intermittently cooled for 7 minutes every 25 minutes to prevent the loss of medicinal material components due to heat generated by grinding.

[0043] Fine grinding: Transfer the powder after the initial grinding to an ultrafine grinder, set the frequency to 25 Hz, grind for 25 minutes, and further grind the powder to a particle size of 250 mesh to increase the surface area of ​​the drug and improve the release rate of the active ingredient.

[0044] Mixing and stirring: Pour the finely ground powders of each flavor into a mixing mixer and stir at 120 rpm for 18 minutes to ensure that the powders are fully mixed.

[0045] Packaging: Use non-woven bags with a weight of 35 g / m2, good air permeability and in compliance with hygiene standards, use an automatic quantitative packaging machine, and put the evenly mixed powder into the non-woven bag according to a certain weight per bag, and then seal and package it to make a Qiyu patch. After packaging, the product is quality tested to ensure that the packaging is complete and undamaged, and the weight of the powder meets the standard.

[0046] Apps for insomnia and irritability Patient's condition: Ms. Li, 38 years old, was diagnosed as having qi stagnation by traditional Chinese medicine. She had been troubled by insomnia and irritability for a long time. She had difficulty falling asleep, had shallow sleep, was easily awakened, had large mood swings during the day, and was prone to losing temper, which had a great impact on her daily life and work.

[0047] Directions: Preparation before use: Before applying the Chinese medicine patch, first gently clean the skin of the area to be applied (Tanzhong, Neiguan, Taichong, Shenmen) with warm water to ensure that the skin is clean, dry and free of dirt, grease and sweat, and then gently dry it with a soft towel. According to the human acupuncture point map or under the guidance of a Chinese medicine practitioner, accurately find the Tanzhong point (located on the chest, horizontally at the 4th intercostal space, on the anterior midline), Neiguan point (located in the anterior area of ​​the forearm, 2 inches above the distal transverse line on the palmar side of the wrist, between the palmaris longus tendon and the radial flexor carpi tendon), Taichong point (located on the dorsum of the foot, between the 1st and 2nd metatarsal bones, in the depression in front of the junction of the metatarsal base, or where the arterial pulsation is touched), and Shenmen point (located in the anterior area of ​​the wrist, at the ulnar end of the distal transverse line on the palmar side of the wrist, and in the depression of the radial edge of the ulnar flexor carpi tendon). Prepare 4 Qi Yu patches according to the severity of your own symptoms.

[0048] Application: Open the Qiyu patch package and carefully take out the patch to avoid spilling the powder. Gently peel off the anti-sticking paper of the patch, align the side with the powder accurately with the determined acupuncture point, and then gently press the edge of the patch with your fingers to make the patch fit tightly to the skin, making sure there are no bubbles or wrinkles between the patch and the skin to ensure that the drug can fully contact the skin and promote absorption.

[0049] Application time control: Apply for about 6 hours each time. During the application period, pay close attention to skin reactions. If you experience discomfort such as itching, stinging, redness, or swelling during the application process, remove the patch immediately and gently clean the application area with clean water to wash off the residual medicine. If the symptoms are mild, such as just slight itching or redness, you can shorten the next application time appropriately after the symptoms are relieved, and continue to observe the skin reaction. If the symptoms are severe, such as blisters, large areas of redness and swelling, etc., stop using it and seek medical attention in time, and treat it under the guidance of a doctor. If there is no discomfort after 6 hours of application, you can remove the patch on time. When removing it, it should be peeled off slowly along the direction of the skin to avoid damaging the skin due to excessive force.

[0050] Effect: After the first day of application, the time to fall asleep was shortened; on the third day, the quality of sleep was significantly improved, the number of awakenings at night was reduced, and the daytime impatience was also relieved; after one course of treatment, the insomnia symptoms were significantly improved, the impatience was significantly reduced, and the emotions were better controlled. After two courses of continuous use, sleep basically returned to normal and the mood became more stable.

[0051] Application for Qi-stagnation constitution with thyroid nodules Patient's condition: Zhang, male, 45 years old, was found to have thyroid nodules during physical examination and was diagnosed as having qi stagnation by traditional Chinese medicine. He often felt chest tightness, depression, and poor mental state.

[0052] Directions: Preparation before use: Clean the skin of the area to be applied (Tanzhong, Qimen, Neiguan, Taichong, and local Ashi points of thyroid nodules) with warm water, making sure the skin is clean, dry, and free of dirt, grease, and sweat, and then wipe it dry with a soft towel. With the help of a human acupuncture point map or with the help of a Chinese medicine practitioner, accurately find Tanzhong, Qimen (located on the chest, the 6th intercostal space, 4 inches away from the anterior midline), Neiguan, Taichong, and the local Ashi points corresponding to the thyroid nodules. Prepare 5 Qiyu patches.

[0053] Application: Open the patch package and carefully take out the patch to avoid spilling the powder. Gently peel off the anti-sticking paper, align the powdered side of the patch accurately with the selected acupoints, apply it to the corresponding acupoints in turn, and gently press the edge of the patch to make it fit the skin tightly, avoiding bubbles or wrinkles, to promote drug absorption.

[0054] Application time control: Apply for about 6 hours each time. Observe the skin condition closely. If skin discomfort occurs, follow the above treatment methods. If there is no discomfort after 6 hours of application, remove the patch on time, and peel it off slowly along the direction of the skin to prevent skin damage.

[0055] Effect: After one course of treatment, the symptoms of chest tightness and discomfort were alleviated, and the mood was improved compared to before; after three courses of treatment, the thyroid nodules tended to shrink, the depressed mood was significantly improved, and the mental state also improved.

[0056] In the above embodiments and specific applications, the Chinese medicine patch involved in this application has the following advantages: ① Significant conditioning effect: The Chinese medicine patch in this application has a scientific formula, and the synergistic effect of multiple medicinal materials such as Albizzia julibrissin, Tangerine peel, and Chuanxiong can effectively soothe the liver and regulate qi, and has a significant conditioning effect on various symptoms and diseases caused by qi stagnation constitution. In the prescription, Albizzia julibrissin can relieve liver depression and calm the mind; Tangerine peel can regulate qi and dispel cold, and strengthen the stomach and intestines; Chuanxiong can promote qi and blood circulation, relieve depression and relieve pain. These medicinal materials are compatible with each other, which can comprehensively regulate human functions and improve qi stagnation constitution. Clinical cases show that this Chinese medicine patch can significantly improve symptoms such as irritability and poor sleep quality, and can also be used as an auxiliary treatment for a variety of qi stagnation-related diseases.

[0057] ② Scientific preparation process: The preparation process covers raw material pretreatment, drying, grinding, mixing and packaging. The parameters are strictly controlled in each link to retain the effective ingredients of the medicinal materials to the greatest extent, ensuring the quality and stability of the Chinese medicine patch. For example, drying at a low temperature of 40-50°C for 5-8 hours can not only remove moisture for easy grinding, but also retain the effective ingredients of the medicinal materials to the greatest extent; after the initial grinding, ultra-fine grinding to 200-300 meshes greatly increases the surface area of ​​the drug, making it easier to release the effective ingredients, improving the utilization rate of the drug, and thus enhancing the conditioning effect.

[0058] ③Easy to use: It adopts the external application method to avoid the bitterness and gastrointestinal irritation of oral drugs, and is suitable for all kinds of people. Users can apply the patch at any time during daily activities according to their own conditions, without complicated operations and professional guidance, which greatly improves the convenience and compliance of conditioning. 2-6 patches per day, each application to the corresponding acupoint for about 6 hours, the operation is simple, and patients can use it by themselves.

[0059] ④ High safety: The medicinal materials used in the Chinese medicine patch, such as Albizzia julibrissin peel, dried tangerine peel, and Chuanxiong, are all natural Chinese medicinal materials. While exerting therapeutic effects, they have fewer adverse reactions and less side effects on the human body than chemical synthetic drugs. Long-term use is not likely to cause damage to liver and kidney functions, etc., and it is especially suitable for people with weak constitutions who are not suitable for strong drug stimulation.

[0060] ⑤ Wide range of applications: It is not only suitable for people with typical Qi stagnation constitution, but also can be used to treat a variety of diseases related to Qi stagnation, such as depression, anxiety, obsessive-compulsive disorder, thyroid nodules, menopausal syndrome, breast hyperplasia, etc., providing a new option for clinical treatment. The Chinese medicine patch can play a conditioning role by applying to the corresponding acupoints for different symptoms, providing an auxiliary means for the treatment of a variety of diseases.

[0061] The above specific embodiments further illustrate the purpose, technical solutions and beneficial effects of the present invention. It should be understood that the above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical solutions and inventive concepts of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

[0062] In addition, in the description of the present invention, it should be understood that the terms indicating orientation or positional relationships are based on the orientation or positional relationships shown in the drawings and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0063] Furthermore, in the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. A Chinese medicine patch for regulating qi stagnation constitution, characterized in that: By weight, the medicinal composition of the Chinese medicine patch includes: 6g of Albizzia julibrissin peel, 4g of dried tangerine peel, 7g of Ligusticum chuanxiong, 4g of clove, 6g of rose, 6g of Tribulus terrestris, 6g of mint, and 8g of lemon.

2. A method for preparing a Chinese medicine patch for regulating qi stagnation constitution as claimed in claim 1, characterized in that: The steps include: S1. Raw material pretreatment: Select high-quality, mildew-free and impurity-free albizzia peel, tangerine peel, chuanxiong, cloves, rose, tribulus terrestris, mint and lemon. Wash and dry tangerine peel and lemon, and remove impurities from other medicinal materials; S2. Drying treatment: Place the pretreated raw materials in a drying device and dry them at 40-50°C for 5-8 hours to reduce the moisture content of the raw materials to less than 8%, which is convenient for subsequent grinding; S3, initial grinding: put the dried raw materials into a common grinder for initial grinding, set the grinding machine speed to 150-200 rpm, control the grinding time to 10-15 minutes, and grind to a particle size of 80-100 mesh; S4, fine grinding: the powder after the initial grinding is transferred to an ultrafine grinding machine, the frequency of the ultrafine grinding machine is set to 20-30 Hz, the grinding time is 20-30 minutes, and further ground to a particle size of 200-300 meshes to increase the surface area of ​​the drug and improve the release rate of the active ingredient; S5, mixing and stirring: pour the finely ground powders of each flavor into a mixing and stirring machine, and stir at a speed of 100-150 rpm for 15-20 minutes to ensure that the powders are fully mixed; S6. Packaging: Put the evenly mixed powder into a non-woven bag that has good air permeability and meets hygiene standards, and use an automatic quantitative packaging machine to seal and package the powder according to a certain weight standard for each bag to make a Qi Yu patch.

3. The method for preparing a Chinese medicine patch for regulating qi stagnation constitution according to claim 2, characterized in that: The drying equipment in step S2 is a vacuum drying oven, and the vacuum degree is controlled at 0.05-0.08 MPa.

4. The method for preparing a Chinese medicine patch for regulating qi stagnation constitution according to claim 2, characterized in that: In step S3, during the initial grinding process, the grinder is intermittently cooled for 5-10 minutes every 20-30 minutes to prevent the loss of drug components due to heat generated by grinding.

5. An application of the Chinese medicine patch for regulating qi stagnation constitution as claimed in claim 1, characterized in that: Used to treat depression, anxiety, neurosis, obsessive-compulsive disorder, insomnia, mania, plum pit qi, lily disease, thyroid nodules, menopausal syndrome, and breast hyperplasia.

6. A method of using the Chinese medicine patch for regulating qi stagnation constitution as claimed in claim 1, characterized in that: The steps include: Preparation before use: Clean the skin of the area to be applied with warm water, make sure the skin is clean, dry and free of dirt, oil and sweat, then gently dry it with a soft towel; select acupuncture points that have the effect of soothing the liver and regulating qi for people with qi stagnation, and prepare 2-6 Chinese medicine patches according to personal constitution, severity of symptoms and instructions for use; Application: Open the patch package and carefully take out the patch to avoid spilling the powder. Gently peel off the anti-sticking paper of the patch and align the side with the powder accurately with the determined acupuncture point. Then gently press the edge of the patch to make it fit the skin tightly. Make sure there are no bubbles or wrinkles between the patch and the skin to ensure that the drug can fully contact the skin and promote absorption. Application time control: Apply for about 6 hours each time; during the application period, pay close attention to skin reactions. If you experience discomfort such as itching, tingling, redness, swelling, etc. during the application process, you should remove the patch immediately and wash the application area with clean water. If the symptoms persist or worsen, you need to seek medical attention in time. If there is no discomfort after 6 hours of application, you can remove the patch on time. When removing it, you should peel it off slowly along the direction of the skin to avoid damaging the skin due to excessive force.

7. The method for using the Chinese medicine patch for regulating qi stagnation constitution according to claim 6, characterized in that: The acupoints are Tanzhong, Neiguan, Taichong and Qimen.

8. The method for using the Chinese medicine patch for regulating qi stagnation constitution according to claim 6, characterized in that: The symptoms of Qi stagnation constitution are mostly thin body, depressed look, fragile emotions, irritability, pale red tongue, thin white fur, stringy pulse, introverted and unstable personality, sensitivity and suspicion, susceptibility to visceral agitation, plum pit qi, lily disease and depression, poor adaptability to mental stimulation, and inability to adapt to one or more of the following: cloudy and rainy weather.

9. The method for using the Chinese medicine patch for regulating qi stagnation constitution according to claim 6, characterized in that: The conditioning treatment course is 5 days.

10. The method for using the Chinese medicine patch for regulating qi stagnation constitution according to claim 6, characterized in that: When using the Chinese medicine patch, you need to avoid certain foods, including alcohol and spicy foods, and your diet should be light.

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