Solid fermentation feed additive for veterinary drugs and preparation method of solid fermentation feed additive

Abstract

The invention discloses a solid fermentation feed additive for veterinary drugs and a preparation method of the solid fermentation feed additive, and belongs to the technical field of veterinary drugs. 18-30 parts of a fermentation auxiliary material; 8 to 12 parts of compound probiotics; 3-8 parts of a biological enzyme; the traditional Chinese medicine mixture is obtained by mixing radix isatidis, pseudo-ginseng, dandelion, radix bupleuri, honeysuckle, liquorice, artemisia capillaris and fructus forsythiae in proportion, and the feed has the beneficial effects that the digestion performance of the feed can be improved through the Chinese herbal medicine components and probiotics, the utilization rate of the feed is increased, and the feed is suitable for being eaten by people. According to the present invention, the feed is added with the probiotics, such that the nutritional components in the feed can be well released and converted, the nutrition waste is reduced so as to improve the use value of the feed, and the Chinese herbal medicine components and the probiotics can stimulate the immune system of animals, enhance the immunity of animals, effectively prevent and control various diseases, and improve the immunity of animals. Death and loss of animals caused by diseases are reduced, and healthy development of the breeding industry is guaranteed.

Description

Technical Field

[0001] The present invention relates to the technical field of veterinary drugs. More specifically, it relates to a solid fermentation feed additive for veterinary drugs and a preparation method thereof. Background Art

[0002] Veterinary drugs refer to substances used for preventing, treating, or diagnosing animal diseases or purposefully regulating the physiological functions of animals. Currently, with the improvement of living standards, the number of farmed livestock and poultry is increasing. Therefore, the demand for veterinary drug solutions is also increasing. Generally, they are prepared by mixing serum products, antibiotics, biochemical drugs, traditional Chinese herbs, etc. in certain specifications. China is the largest poultry farming country in the world. The healthy and sustainable development of the livestock and poultry breeding industry is related to the national economy and people's livelihood. With the development of technology, high-density and large-scale farming have led to frequent poultry diseases, the problems of abuse and misuse of antibiotics, and thus drug resistance, resulting in longer treatment processes, stronger pathogens, and worse treatment effects, forming a vicious cycle. Summary of the Invention

[0003] (1) Technical Problems to be Solved

[0004] Aiming at the deficiencies of the existing technology, the purpose of the present invention is to provide a solid fermentation feed additive for veterinary drugs and a preparation method thereof, which have the characteristics of improving the utilization rate of feed and enhancing the immunity of animals.

[0005] (2) Technical Solutions

[0006] To achieve the above purpose, the present invention provides a solid fermentation feed additive for veterinary drugs, which comprises the following component raw materials in parts by weight: 32 - 48 parts of traditional Chinese medicine mixture; 18 - 30 parts of fermentation auxiliary materials; 8 - 12 parts of compound probiotics; 3 - 8 parts of biological enzymes; 15 - 23 parts of sterile pure water. The traditional Chinese medicine mixture is obtained by mixing Isatis indigotica, Panax notoginseng, Taraxacum mongolicum, Bupleurum chinense, Lonicera japonica, Glycyrrhiza uralensis, Artemisia capillaris, and Forsythia suspensa in proportion. The fermentation auxiliary materials are obtained by mixing soybean meal, corncob, peanut shell, and sucrose in proportion. The compound probiotics are obtained by mixing Saccharomyces cerevisiae, Bifidobacterium, Bacillus subtilis, and Lactobacillus plantarum in proportion. The biological enzymes are obtained by mixing cellulase, pectin, xylanase, glucanase, and mannanase in proportion.

[0007] As a further scheme of the present invention: the ratio of Isatis indigotica, Panax notoginseng, Taraxacum mongolicum, Bupleurum chinense, Lonicera japonica, Glycyrrhiza uralensis, Artemisia capillaris, and Forsythia suspensa in the traditional Chinese medicine mixture is 1.8:0.3:1.5:0.5:1.2:0.7:1.2:0.8.

[0008] As a further scheme of the present invention: the ratio of soybean meal, corncob, peanut shell, and sucrose in the fermentation auxiliary materials is 1.8:1.2:1:0.4.

[0009] As a further solution of the present invention: the ratio of yeast, Bifidobacterium, Bacillus subtilis and Lactobacillus plantarum in the compound probiotics is 0.8:0.7:1.2:0.5.

[0010] As a further solution of the present invention: the ratio of cellulase, pectin, xylanase, glucanase and mannanase in the bio-enzyme is 1.8:1.2:0.5:0.7:0.8.

[0011] A veterinary solid fermentation feed additive and its preparation method, comprising the following steps:

[0012] Step 1: Wash the selected Isatis root, Panax notoginseng, dandelion, Bupleurum chinense, honeysuckle, liquorice, Artemisia capillaris, forsythia, soybean meal, corncob and peanut shell respectively, and then dry them in the air for 2 - 3 days;

[0013] Step 2: Crush the dried Isatis root, Panax notoginseng, dandelion, Bupleurum chinense, honeysuckle, liquorice, Artemisia capillaris and forsythia respectively, pass them through a 60-mesh sieve, and mix them in proportion to obtain a traditional Chinese medicine mixture;

[0014] Step 3: Crush the dried soybean meal, corncob and peanut shell respectively, pass them through a 60-mesh sieve, and add an appropriate amount of sucrose and mix them in proportion to obtain a fermentation auxiliary material;

[0015] Step 4: Mix the prepared traditional Chinese medicine mixture and fermentation auxiliary material evenly in proportion, sterilize them at 110 - 135°C for 30 minutes, and then dry the prepared material for standby;

[0016] Step 5: Respectively expose the refrigerated yeast, Bifidobacterium, Bacillus subtilis and Lactobacillus plantarum to room temperature in a sterile environment, and then mix them in proportion to obtain compound probiotics;

[0017] Step 6: Respectively expose the refrigerated cellulase, pectin, xylanase, glucanase and mannanase to room temperature in a sterile environment, and then mix them in proportion to obtain a bio-enzyme;

[0018] Step 7: Mix the prepared material, compound probiotics and bio-enzyme evenly in proportion, put them into the sterilized fermentation tank, and inject an appropriate amount of sterile pure water for uniform stirring;

[0019] Step 8: Aerobically ferment the mixture in the fermentation tank for 1 - 3 days and anaerobically ferment it for 3 - 5 days, and then spray-dry the fermented product to obtain the veterinary solid fermentation feed additive.

[0020] (3) Beneficial effects

[0021] In summary, the present invention has the following beneficial effects: The Chinese herbal medicine components and probiotics in the present invention can improve the digestive performance of feed, increase the utilization rate of feed, enable better release and conversion of the nutritional components in the feed, reduce nutritional waste, thereby improving the use value of the feed, and can stimulate the immune system of animals and enhance the immunity of animals through the Chinese herbal medicine components and probiotics, effectively preventing and controlling the occurrence of various diseases, reducing the death and losses caused by diseases to animals, and ensuring the healthy development of the aquaculture industry. Detailed implementation manners

[0022] To make the technical means, creative features, achieved purposes and functions of the present invention easy to understand, the technical solutions in the detailed implementation manners of the present invention are clearly and completely described below to further elaborate the present invention. Obviously, the described detailed implementation manners are only a part of the implementation manners of the present invention, rather than all the styles.

[0023] Example:

[0024] The present invention provides the following technical solutions: A veterinary solid fermentation feed additive, comprising the following components in parts by weight: 32 - 48 parts of a Chinese medicine mixture; 18 - 30 parts of a fermentation auxiliary material; 8 - 12 parts of a compound probiotic; 3 - 8 parts of a biological enzyme; 15 - 23 parts of sterile pure water. The Chinese medicine mixture is obtained by mixing Isatis root, Notoginseng, Dandelion, Bupleurum, Honeysuckle, Licorice, Artemisia capillaris and Forsythia suspensa in proportion. The fermentation auxiliary material is obtained by mixing soybean meal, corncob, peanut shell and sucrose in proportion. The compound probiotic is obtained by mixing yeast, Bifidobacterium, Bacillus subtilis and Lactobacillus plantarum in proportion. The biological enzyme is obtained by mixing cellulase, pectin, xylanase, glucanase and mannanase in proportion.

[0025] Specifically, the ratio of Isatis root, Notoginseng, Dandelion, Bupleurum, Honeysuckle, Licorice, Artemisia capillaris and Forsythia suspensa in the Chinese medicine mixture is 1.8:0.3:1.5:0.5:1.2:0.7:1.2:0.8.

[0026] Specifically, the ratio of soybean meal, corncob, peanut shell and sucrose in the fermentation auxiliary material is 1.8:1.2:1:0.4.

[0027] Specifically, the ratio of yeast, Bifidobacterium, Bacillus subtilis and Lactobacillus plantarum in the compound probiotic is 0.8:0.7:1.2:0.5.

[0028] Specifically, the ratio of cellulase, pectin, xylanase, glucanase and mannanase in the biological enzyme is 1.8:1.2:0.5:0.7:0.8.

[0029] A veterinary solid fermentation feed additive and its preparation method, comprising the following steps:

[0030] Step 1: Wash the selected Radix Isatidis, Radix Notoginseng, Taraxaci, Radix Bupleuri, Flos Lonicerae, Flos Licoricees, Artemisia Capillaris, Fructus Forsythiae, soybean meal, corn cobs and peanut shells respectively and dry them for 2-3 days;

[0031] Step 2: Grind the dried Radix Isatidis, Radix Notoginseng, Herba Taraxaci, Radix Bupleuri, Flos Lonicerae, Radix Glycyrrhizae, Artemisia Capillaris and Fructus Forsythiae respectively, pass through a 60-mesh sieve, and mix them according to proportion to obtain a Chinese medicine mixture;

[0032] Step 3: Grind the dried soybean meal, corn cobs and peanut shells respectively, pass them through a 60-mesh sieve, and add an appropriate amount of sucrose in proportion to obtain fermentation auxiliary materials;

[0033] Step 4: Mix the prepared Chinese medicine mixture and fermentation auxiliary materials in proportion and stir evenly, sterilize at 110-135° C. for 30 minutes, and then dry the prepared materials for later use;

[0034] Step 5: respectively drying the refrigerated yeast, bifidobacterium, bacillus subtilis and lactobacillus plantarum to room temperature in a sterile environment and then mixing them in proportion to obtain a composite probiotic;

[0035] Step 6: respectively drying the refrigerated cellulase, pectin, xylanase, glucanase and mannanase in a sterile environment to room temperature and then mixing them in proportion to obtain biological enzymes;

[0036] Step 7: Mix the prepared materials, compound probiotics and biological enzymes in proportion and stir them evenly, then put them into the sterilized fermentation tank, and inject an appropriate amount of sterile pure water for even stirring;

[0037] Step 8: aerobically ferment the mixture in the fermentation tank for 1-3 days and anaerobic fermentation for 3-5 days, and spray-dry the fermented product to obtain the veterinary solid fermented feed additive.

[0038] The working principle of the present invention is as follows: When the present invention is in use, first, the selected isatis root, notoginseng, dandelion, bupleurum, honeysuckle, liquorice, artemisia capillaris, forsythia, soybean meal, corncob and peanut shell are respectively washed and then dried for 2 - 3 days. And the dried isatis root, notoginseng, dandelion, bupleurum, honeysuckle, liquorice, artemisia capillaris and forsythia are respectively pulverized and then passed through a 60 - mesh sieve, and then mixed in proportion to obtain a traditional Chinese medicine mixture. At the same time, the dried soybean meal, corncob and peanut shell are respectively pulverized and then passed through a 60 - mesh sieve, and an appropriate amount of sucrose is added and mixed in proportion to obtain a fermentation auxiliary material. Then, the prepared traditional Chinese medicine mixture and fermentation auxiliary material are mixed and stirred evenly and then sterilized at 110 - 135 °C for 30 minutes. Then, the prepared material is dried and reserved. And the refrigerated yeast, bifidobacterium, bacillus subtilis and lactobacillus plantarum are respectively dried in a sterile environment to room temperature and then mixed in proportion to obtain a compound probiotic. At the same time, the refrigerated cellulase, pectin, xylanase, glucanase and mannanase are respectively dried in a sterile environment to room temperature and then mixed in proportion to obtain a biological enzyme. Then, the prepared material, compound probiotic and biological enzyme are mixed and stirred evenly and then put into the sterilized fermentation tank, and an appropriate amount of sterile pure water is injected for uniform stirring. Finally, the mixture in the fermentation tank is subjected to aerobic fermentation for 1 - 3 days and anaerobic fermentation for 3 - 5 days, and the fermented product after fermentation is spray - dried to obtain a veterinary drug solid - state fermentation feed additive.

[0039] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent substitution on some of the technical features. Any modification, equivalent substitution, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A solid fermented feed additive for veterinary medicine, characterized in that: The invention comprises the following raw materials in parts by weight: 32-48 parts of a Chinese medicine mixture; 18-30 parts of fermentation auxiliary materials; 8-12 parts of compound probiotics; 3-8 parts of biological enzymes; and 15-23 parts of sterile pure water. The Chinese medicine mixture comprises Radix Isatidis, Radix Notoginseng, Herba Taraxaci, Radix Bupleuri, Flos Lonicerae, Radix Glycyrrhizae, Artemisia Capillaris and Fructus Forsythiae, which are mixed in proportion; the fermentation auxiliary materials comprise soybean meal, corn cob, peanut shell and sucrose, which are mixed in proportion; the compound probiotics comprise yeast, Bifidobacterium, Bacillus subtilis and Lactobacillus plantarum, which are mixed in proportion; and the biological enzymes comprise cellulase, pectin, xylanase, glucanase and mannanase, which are mixed in proportion.

2. The solid fermentation feed additive for veterinary medicine according to claim 1, characterized in that: The ratio of Radix Isatidis, Radix Notoginseng, Herba Taraxaci, Radix Bupleuri, Flos Lonicerae, Flos Licorices, Artemisia Capillaris and Fructus Forsythiae in the Chinese medicine mixture is 1.8:0.3:1.5:0.5:1.2:0.7:1.2:0.

8.

3. The solid fermentation feed additive for veterinary medicine according to claim 1, characterized in that: The ratio of soybean meal, corn cobs, peanut shells and sucrose in the fermentation auxiliary materials is 1.8:1.2:1:0.

4.

4. The solid fermentation feed additive for veterinary medicine according to claim 1, characterized in that: The ratio of yeast, bifidobacterium, bacillus subtilis and lactobacillus plantarum in the composite probiotics is 0.8:0.7:1.2:0.

5.

5. The solid fermentation feed additive for veterinary medicine according to claim 1, characterized in that: The ratio of cellulase, pectinase, xylanase, glucanase and mannanase in the biological enzymes is 1.8:1.2:0.5:0.7:0.

8.

6. A method for preparing a solid fermented feed additive for veterinary medicine according to any one of claims 1 to 6, characterized in that: The steps include: Step 1: Wash the selected Radix Isatidis, Radix Notoginseng, Taraxaci, Radix Bupleuri, Flos Lonicerae, Flos Licoricees, Artemisia Capillaris, Fructus Forsythiae, soybean meal, corn cobs and peanut shells respectively and dry them for 2-3 days; Step 2: Grind the dried Radix Isatidis, Radix Notoginseng, Herba Taraxaci, Radix Bupleuri, Flos Lonicerae, Radix Glycyrrhizae, Artemisia Capillaris and Fructus Forsythiae respectively, pass through a 60-mesh sieve, and mix them according to proportion to obtain a Chinese medicine mixture; Step 3: Grind the dried soybean meal, corn cobs and peanut shells respectively, pass them through a 60-mesh sieve, and add an appropriate amount of sucrose in proportion to obtain fermentation auxiliary materials; Step 4: Mix the prepared Chinese medicine mixture and fermentation auxiliary materials in proportion and stir evenly, sterilize at 110-135° C. for 30 minutes, and then dry the prepared materials for later use; Step 5: respectively drying the refrigerated yeast, bifidobacterium, bacillus subtilis and lactobacillus plantarum in a sterile environment to room temperature and then mixing them in proportion to obtain composite probiotics; Step 6: respectively drying the refrigerated cellulase, pectin, xylanase, glucanase and mannanase in a sterile environment to room temperature and then mixing them in proportion to obtain biological enzymes; Step 7: Mix the prepared materials, compound probiotics and biological enzymes in proportion and stir them evenly, then put them into the sterilized fermentation tank, and inject an appropriate amount of sterile pure water for even stirring; Step 8: aerobically ferment the mixture in the fermentation tank for 1-3 days and anaerobic fermentation for 3-5 days, and spray-dry the fermented product to obtain the veterinary solid fermented feed additive.