Non-contact cardiopulmonary monitor for experimental animal in anesthetic state

Abstract

The invention particularly relates to a non-contact cardiopulmonary monitor for an experimental animal in an anesthetic state, which comprises the following steps: placing an anesthetized animal to be monitored on the cardiopulmonary monitor, and generating a thermodynamic diagram for early warning in real time through an infrared thermal imaging sensor; infrared laser irradiates a reflection patch attached to the chest or the heart of the experimental animal, and a camera collects emitted laser and analyzes the emitted laser in real time to generate a breathing oscillogram; the final vital sign parameters of the animal in the experiment are judged based on the thermodynamic diagram and the respiratory oscillogram parameters so as to monitor whether the animal has life danger or not; according to the system, non-contact monitoring can be carried out when heart and lung monitoring is carried out on an animal, the infrared laser tube irradiates on the reflective sticker to form an incidence light path and a reflection light path, the infrared photosensitive camera receives the reflection light path, a breathing oscillogram is obtained through analysis and serves as breathing early warning, and the infrared thermal imaging sensor generates thermodynamic diagram early warning in real time; and judging the final vital sign parameters of the animal in the experiment based on the thermodynamic diagram and the respiratory oscillogram parameters so as to monitor whether the animal has life danger or not.

Description

Technical Field

[0001] The present invention relates to the technical field of animal experiments, and particularly to a non-contact cardiopulmonary monitor for experimental animals under anesthesia. Background Art

[0002] With the in-depth development of life science research and drug development, the cardiopulmonary function monitoring of experimental animals has become an indispensable part. Traditional cardiopulmonary monitoring methods mostly rely on physical contact, such as directly contacting the animal through sensors or electrodes for monitoring. Although these contact monitoring methods can provide real-time data, they may cause unnecessary stress responses to experimental animals, affecting the accuracy and reliability of experimental results. At the same time, frequent physical contact also increases the physiological burden on animals and may interfere with their normal physiological state, further affecting the authenticity of experimental data. Therefore, how to reduce the interference to experimental animals and adopt more accurate and efficient monitoring technologies has become a major challenge in current animal experiments.

[0003] In animal experiments, anesthesia is a commonly used means to ensure that animals remain stable during the experiment. However, due to improper anesthesia depth or individual tolerance differences in animals, animal deaths often occur during the anesthesia process or the recovery stage. Therefore, there is an urgent need for a device that can monitor the cardiopulmonary function of animals in real time and give early warnings, so that experimenters can perform early intervention and rescue when the vital signs are abnormal. In addition, traditional contact monitoring methods will increase the interference factors in the experiment and affect the reliability of experimental results. Therefore, the development of a non-contact monitoring device that can not only effectively eliminate external interference but also achieve accurate vital sign monitoring without affecting the experimental environment has become the demand of current technological development.

[0004] To solve this problem, in recent years, non-contact cardiopulmonary monitoring technologies have gradually attracted attention. Such technologies use non-contact means such as infrared, laser, and optical sensing to monitor the cardiopulmonary function of animals, and realize the real-time monitoring of animal vital signs by obtaining information such as reflected signals, thermodynamic changes, and respiratory waveforms on the animal body surface. In particular, infrared light sensing technology and infrared thermal imaging technology have shown good application prospects in non-contact monitoring. Compared with traditional methods, non-contact monitoring can not only reduce the interference to experimental animals but also improve the accuracy and efficiency of monitoring. However, most of the existing non-contact cardiopulmonary monitoring devices have problems such as single function, low adjustment accuracy, and limited monitoring range, and have not been able to fully meet the requirements under complex experimental conditions.

[0005] For example, a novel EPR animal experiment platform with the patent number CN117653488A and its usage method. A novel EPR animal experiment platform includes a peristaltic pump, a membrane oxygenator, and a variable-temperature water tank. It also includes a constant-temperature box and a heat exchanger. The constant-temperature box includes a housing, a base, and a refrigeration system. At the top inside the housing, there is an air circulation fan. On the front of the housing, there is an operation window. Above the operation window, there is an observation window. On one side of the housing, there is an oxygen inlet. On the base, there is an animal fixation table that can be heated. The present invention also discloses a usage method of a novel EPR animal experiment platform. By adopting the above novel EPR animal experiment platform and its usage method, high-quality cardiopulmonary support, rapid cooling, and controllable rewarming are achieved, which helps to improve the treatment rate, survival rate, and good neurological recovery of traumatic cardiac arrest. The above device does not have a cardiopulmonary detection function when conducting experiments on animals, so it cannot give early warnings in a timely manner and cannot intervene and rescue the warned animals.

[0006] Therefore, we provide a non-contact cardiopulmonary monitor for experimental animals under anesthesia that can achieve non-contact monitoring of the cardiopulmonary function of experimental animals. Summary of the Invention

[0007] The purpose of the present invention is to overcome the deficiencies in the prior art and provide a non-contact cardiopulmonary monitor for experimental animals under anesthesia.

[0008] The purpose of the present invention is achieved as follows: A non-contact cardiopulmonary monitor for experimental animals under anesthesia includes a bottom plate. On the bottom plate, there is a placement plate. An arc-shaped frame is movably arranged on the bottom plate in the front-back direction. There are three slider mechanisms on the arc-shaped frame, and the slider mechanisms can move along the arc-shaped frame. From left to right on the slider mechanisms, there are an infrared photosensitive camera, an infrared thermal imaging sensor, and an infrared laser tube respectively. On the bottom plate, there are an indicator light mechanism one and an indicator light mechanism two. The indicator light mechanism one can move left and right along the bottom plate, and the indicator light mechanism two can move back and forth along the bottom plate. The indicator light mechanism one and the indicator light mechanism two have the same structure. The indicator light mechanism one includes a lifting rod. At the upper end of the lifting rod, there is an indicator light, and the lifting rod can drive the indicator light to move up and down.

[0009] Furthermore, a lifting mechanism and a translation mechanism are arranged between the placement plate and the bottom plate. The lifting mechanism is arranged on the bottom plate, and the translation mechanism is arranged above the lifting mechanism. The lifting mechanism drives the translation mechanism to move up and down, and the placement plate is arranged on the translation mechanism. The translation mechanism drives the placement plate to move horizontally.

[0010] Furthermore, a lifting mechanism is arranged between the arc-shaped frame and the bottom plate. There is one lifting mechanism at the bottom of each of the left and right sides of the arc-shaped frame, and the lifting mechanism drives the arc-shaped frame to move up and down.

[0011] Further, the lifting mechanism includes a fixed cylinder, in which a lifting cylinder is arranged to be movable up and down. The upper end of the lifting cylinder is connected to the bottom of the arc-shaped frame. A first lifting electric cylinder is arranged between the lifting cylinder and the fixed cylinder, and the first lifting electric cylinder drives the lifting cylinder to move up and down.

[0012] When the present invention is used, the animal to be monitored after anesthesia is placed on the cardiopulmonary monitor, and the reflective sticker is pasted on the heart or chest of the experimental animal and kept horizontally placed to prevent the reflected light irradiated on the reflective sticker from not being received by the infrared sensitive camera.

[0013] The reflective sticker on the detection part of the animal to be detected is marked by the position determination mechanism.

[0014] The position is measured by the position determination mechanism, that is, the position of the reflective sticker is cross-marked by the first indicator light mechanism and the second indicator light mechanism. At the same time, the first indicator light mechanism and the second indicator light mechanism can move up and down to enable the indicator lights to move up and down, so as to realize the correspondence of the height of the upper and lower positions of the reflective sticker. The indicator lights emitted by the indicator light mechanism are horizontal light rays. At the same time, move the first indicator light mechanism and the second indicator light mechanism to realize the vertical cross-marking of the position of the reflective sticker. The up and down height of the reflective sticker relative to the bottom plate is recorded by the up and down movement of the indicator light mechanism, and the horizontal position information of the reflective sticker on the bottom plate can be obtained through the horizontal movement positions of the two indicator light mechanisms.

[0015] The position determination mechanism transmits the measured position information to the controller. After obtaining the position information, the controller controls the translation mechanism to move, and positions the marked position at the middle position of the bottom plate, that is, the movement of the marked position is realized by controlling the first driving mechanism and the second driving mechanism in the translation mechanism.

[0016] That is, when the translation mechanism drives the marked position to move horizontally, by controlling the first driving mechanism to drive the longitudinal guide rail to move left and right along the transverse guide rail, and controlling the second driving mechanism to drive the placement plate to move back and forth along the longitudinal guide rail, the horizontal movement of the marked position is realized, so as to position the marked position at the middle position of the bottom plate, which is convenient for the subsequent infrared laser tube and infrared sensitive camera to always keep the irradiation position and the receiving position unchanged when moving on the arc-shaped frame.

[0017] At the same time, the controller controls the lifting mechanism to lift the height of the marked position, and at the same time cooperates with the lifting mechanism to drive the arc-shaped frame to move up and down, and adjusts the height of the marked position to the central position of the arc-shaped frame, which is convenient for the infrared laser tube and infrared sensitive camera to always keep the irradiation position and the receiving position unchanged when moving on the arc-shaped frame.

[0018] That is, when the lifting mechanism drives the marked position to move up and down, the telescopic movement of the second lifting electric cylinder is controlled to drive the folding plate to unfold and fold, thereby driving the lifting plate to move up and down, and then realizing the up and down movement of the marked position on the placement plate; when the lifting mechanism moves up and down, the telescopic movement of the first lifting electric cylinder is controlled to drive the lifting cylinder to move up and down, and then realizing the up and down movement of the arc-shaped frame.

[0019] Then, the third driving mechanism is controlled to drive the lifting mechanism to move back and forth, that is, the third driving mechanism drives the guide rod to rotate, and then drives the fixed cylinder to move back and forth, realizing the back and forth movement of the lifting mechanism, so that the irradiation and receiving positions of the infrared laser tube and the infrared photosensitive camera correspond to the reflective sticker.

[0020] The controller controls the infrared photosensitive camera, the infrared thermal imaging sensor, and the infrared laser tube to move to the specified position, realizing the formation of incident and reflected light paths by irradiating the reflective sticker with the infrared laser tube, the infrared photosensitive camera receiving the reflected light path, and obtaining the respiratory waveform diagram through analysis as a respiratory warning. The lens of the infrared thermal imaging sensor is perpendicular to the reflective sticker to photograph the whole body of the animal or the heart or chest of the animal. The infrared thermal imaging sensor generates a thermal diagram warning in real time; based on the parameters of the thermal diagram and the respiratory waveform diagram, the final vital sign parameters of the animal in the experiment are judged to monitor whether the animal is in life danger. The determination of the parameters of the thermal diagram and the respiratory waveform diagram is the prior art and will not be described in detail technically. As long as the functions required by this application can be realized, when it is monitored that the animal is in life danger, other warning signals can be fed back to the operator in time (for example, through an alarm bell, etc.).

[0021] When it is necessary to change the irradiation angle or the light receiving angle of the infrared laser tube and the infrared photosensitive camera on the reflective sticker, the fourth driving mechanism arranged on the slider is used to drive the slider to move along the arc-shaped frame. Specifically, the technical solution of the fourth driving mechanism for driving the slider to move is not technically limited, and as long as the movement can be realized, it is the prior art.

[0022] When it is necessary to adjust or finely adjust the positions of the infrared laser tube, the infrared photosensitive camera, and the infrared thermal imaging sensor, the rotation of the support frame can be realized by rotating the rotating plate, and then the rotating block is driven to rotate. Moreover, the rotating block can be rotated to adjust the angle of the rotating block relative to the slider, and then the rotation angles of the infrared laser tube, the infrared photosensitive camera, and the infrared thermal imaging sensor are adjusted, and then the position adjustment of them is realized. The driving method and the connection structure of the rotation of the rotating block and the support frame are not technically limited, and as long as the position adjustment function required by this application can be realized, it is the prior art. The infrared laser tube, the infrared photosensitive camera, and the infrared thermal imaging sensor are the prior art and will not be described in detail technically, and the realization of the functions of the above infrared laser tube, infrared photosensitive camera, and infrared thermal imaging sensor is the prior art and will not be described in detail technically.

[0023] In addition, when the left semiconductor infrared laser emitter emits a beam of light, the light is focused through the emitter lens to make the light become concentrated and form a dot, and finally irradiates on the reflective sticker attached to the animal. The up-and-down undulation of the reflective sticker will change the change of the light spot captured by the infrared sensitive camera, form a position difference into a data difference and transmit it to the controller. The controller analyzes the change amplitude of the up-and-down position of the reflective sticker to control the infrared sensitive camera to move along the arc frame (or infrared laser tube) to ensure that the emission and reception of light by the infrared laser tube and the infrared sensitive camera reach the best effect; or adjust the up-and-down height of the arc frame through the controller, adjust it through the lifting mechanism, or adjust the height of the placement board, and adjust the lifting position of the placement board through the lifting mechanism; the beam emitted by the semiconductor laser irradiates on the target, and the receiver lens gathers the light reflected by the target and focuses it on the photosensitive element. When the distance from the target changes, the angle of the reflected light passing through the infrared sensitive camera will also change accordingly, and the light is focused at the position on the infrared sensitive camera.

[0024] The above functions of controlling and timely adjusting each electrical component through the controller are prior arts and will not be described in detail in terms of technology. As long as the functions required by this application can be achieved; what this application mainly protects is this application of the device and the non-contact monitoring method for automatically realizing the cardiopulmonary monitoring of animals by this device.

[0025] The innovative functions of the technical solution of the present invention are as follows: High-precision positioning and monitoring: Through the cooperation of the indicator light mechanism and the position determination system, the position of the reflective sticker of the experimental animal can be accurately calibrated, ensuring that the infrared sensitive camera, the infrared thermal imaging sensor and the infrared laser tube are always aligned with the marked position, greatly improving the accuracy of monitoring. Flexible adjustment function: By using the lifting, translation and lifting mechanisms, the position of the reflective sticker and the monitoring area can be flexibly adjusted in terms of height, position and angle according to needs, so as to ensure that the device can always maintain the best monitoring effect under different experimental conditions. Real-time vital sign monitoring and early warning: Combining the infrared thermal imaging sensor and the infrared sensitive camera, the device can generate a thermal map and a respiratory waveform map in real time. By analyzing these images and data, the changes in the vital signs of the animal can be detected in time, providing early warning and helping the operator to quickly respond to potential life risks.

[0026] Automated Operation and Precise Control: Through an intelligent controller, the device can automatically adjust the position, angle, and status of each component, reducing the errors caused by manual operation, improving the convenience and efficiency of operation, and ensuring a high degree of precision during the monitoring process. Non-contact Monitoring: Different from traditional contact monitoring methods, the device uses a non-contact method for cardiopulmonary monitoring, avoiding the animal stress response and physiological burden brought by contact, thus improving the reliability of the experiment and animal welfare. Multi-sensor Collaborative Work: The device integrates a variety of advanced technologies such as infrared laser tubes, infrared sensitive cameras, and infrared thermal imaging sensors, and can monitor the vital signs of animals from multiple dimensions, providing more comprehensive and accurate monitoring data for experimenters.

[0027] Intelligent Regulation and Optimization: The controller can adjust in real time according to the monitoring data and automatically optimize various parameters of the device, such as the irradiation and reception angles of the infrared laser tube and the sensitive camera, to ensure the best quality and accuracy of the data. Enhancing the Safety and Ethics of Animal Experiments: The non-contact design significantly reduces the interference to experimental animals and the stress response of animals, thus enhancing the safety and ethics of the experiment and meeting the high standards of modern experimental animal management. Fast Response and Data Processing: The control system can quickly respond to changes in animal vital signs and process the monitoring data in real time to ensure timely feedback in case of abnormalities, guaranteeing the effectiveness of the experiment and the safety of animals.

[0028] Easy to Maintain and Operate: The device adopts a modular design, which is convenient for maintaining and replacing each sensor module. At the same time, the intelligent operation interface enables operators to easily adjust the monitoring parameters, improving the usability and maintenance efficiency of the device. Reducing Human Errors: The automated adjustment system can eliminate the errors caused by manual operation, ensuring the stability and accuracy during the monitoring process, and providing more reliable experimental data for researchers. Wide Application Prospects: This technical solution is applicable to the monitoring of a variety of experimental animals, has strong adaptability, and can be flexibly expanded according to different experimental needs to meet the requirements of various scientific research and clinical experiments.

[0029] · Beneficial effects: The device can perform non-contact cardiopulmonary monitoring on animals. Simply place the animal on the placement board, and through the position determination mechanism, determine the position of the part of the animal to be detected. Then, it can automatically position the part of the animal to be detected with the central axis position of the arc-shaped rod, and automatically focus the irradiation positions of the infrared laser tube, the infrared sensitive camera, and the infrared thermal imaging sensor on the part of the animal to be detected. The infrared laser tube irradiates on the reflective sticker to form incident and reflected light paths, and the infrared sensitive camera receives the reflected light path. By analyzing, a respiratory waveform diagram is obtained as a respiratory warning. The lens of the infrared thermal imaging sensor is perpendicular to the reflective sticker to photograph the entire body of the animal or the heart or chest of the animal. The infrared thermal imaging sensor generates a thermal map warning in real time; based on the parameters of the thermal map and the respiratory waveform diagram, the final vital sign parameters of the animal in the experiment are judged to monitor whether the animal is in life danger. And when it is necessary to adjust or fine-tune the positions of the infrared laser tube, the infrared sensitive camera, and the infrared thermal imaging sensor, the rotation of the support frame can be achieved by rotating the rotating plate, and then the rotating block is driven to rotate. And the rotating block can be rotated to adjust the angle of the rotating block relative to the slider, and then adjust the rotation angles of the infrared laser tube, the infrared sensitive camera, and the infrared thermal imaging sensor, so as to achieve the adjustment of their positions.

[0030] Through the cooperation of the high-precision positioning of the device and the position determination system, the position of the reflective sticker of the experimental animal is accurately marked, ensuring that the infrared sensitive sensor, the infrared thermal imaging sensor, and the infrared sensitive laser tube are all aligned with the position mark, thus realizing the positioning of the heart and lungs and ensuring accurate monitoring results. Description of the Drawings

[0031] Figure 1 It is a schematic structural diagram of the invention.

[0032] Figure 2 It is a schematic upper structure diagram of the invention.

[0033] Figure 3 It is a partial structural cross-sectional view of the invention.

[0034] Figure 4 It is a schematic structural diagram of the first lifting electric cylinder of the invention.

[0035] Figure 5 It is a flow chart of the usage method of the invention.

[0036] Figure 6 It is a schematic diagram of information processing of the invention.

[0037] Explanation of the Reference Numerals:

[0038] 1. Bottom plate, 2. Fixed cylinder, 3. Guide rod, 4. Lifting plate, 5. Indicator mechanism II, 6. Horizontal guide rail, 7. Longitudinal guide rail, 8. Indicator mechanism I, 9. Placing plate, 10. Lifting cylinder, 11. Arc-shaped frame, 12. Slide block, 13. Infrared laser tube, 14. Infrared thermal imaging sensor, 15. Infrared sensitive camera, 16. Rotating plate, 17. Support frame, 18. Rotating block, 19. Lifting electric cylinder II, 20. Connecting plate, 21. Folding plate, 22. Lifting electric cylinder I. Detailed implementation mode

[0039] Example 1, as Figures 1-6 shown, the object of the present invention is achieved as follows: A non-contact cardiopulmonary monitor for experimental animals under anesthesia includes a bottom plate 1, a placing plate 9 is arranged on the bottom plate 1, an arc-shaped frame 11 is movably arranged on the bottom plate 1 in the front-back direction, three slide block mechanisms are arranged on the arc-shaped frame 11, the slide block mechanisms can move along the arc-shaped frame 11, and an infrared sensitive camera 15 (infrared laser image collector), an infrared thermal imaging sensor 14, and an infrared laser tube 13 (infrared laser emitter) are respectively arranged on the slide block mechanisms from left to right; an indicator mechanism I 8 and an indicator mechanism II 5 are arranged on the bottom plate 1, the indicator mechanism I 8 can move left and right along the bottom plate 1, the indicator mechanism II 5 can move back and forth along the bottom plate 1, the indicator mechanism I 8 and the indicator mechanism II 5 have the same structure, the indicator mechanism I 8 includes a lifting rod, an indicator is arranged at the upper end of the lifting rod, and the lifting rod can drive the indicator to move up and down; the lights emitted by the indicators in the indicator mechanism I 8 and the indicator mechanism II 5 are vertically cross-emitted, and the emitted lights are horizontal rays.

[0040] A lifting mechanism and a translation mechanism are arranged between the placing plate 9 and the bottom plate 1. The lifting mechanism is arranged on the bottom plate 1, the translation mechanism is arranged above the lifting mechanism, the lifting mechanism drives the translation mechanism to move up and down, and the placing plate is arranged on the translation mechanism, and the translation mechanism drives the placing plate 9 to move horizontally.

[0041] A lifting mechanism is arranged between the arc-shaped frame 11 and the bottom plate 1. A lifting mechanism is respectively arranged at the bottom of the left and right sides of the arc-shaped frame 11, and the lifting mechanism drives the arc-shaped frame 11 to move up and down. The lifting mechanism includes a fixed cylinder 2, a lifting cylinder 10 is movably arranged up and down in the fixed cylinder 2, the upper end of the lifting cylinder 10 is connected to the bottom of the arc-shaped frame 11, a lifting electric cylinder I 22 is arranged between the lifting cylinder 10 and the fixed cylinder 2, and the lifting electric cylinder I 22 drives the lifting cylinder 10 to move up and down. Two guide rods 3 are symmetrically arranged left and right between the lifting mechanism and the bottom plate 1. The guide rods 3 are rotatably arranged on the bottom plate 1, the lower part of the fixed cylinder 2 is movably arranged on the guide rods 3 in the front-back direction, the fixed cylinder 2 and the guide rods 3 are in threaded connection, and a driving mechanism III is arranged on the bottom plate 1 at one end of each guide rod 3, and the driving mechanism III drives the guide rods 3 to rotate.

[0042] The lifting mechanism includes a lifting plate 4, two lifting electric cylinders II 19 symmetrically arranged at the front and rear below the lifting plate 4. Connecting plates 20 are fixedly arranged at both ends of the lifting electric cylinders II 19. Folding plates 21 are rotatably arranged at the upper and lower ends of the connecting plates 20 respectively. The upper folding plate 21 is rotatably connected to the lifting plate 4, and the lower folding plate 21 is rotatably connected to the bottom plate 1. The upper and lower folding plates 21 are driven by the lifting electric cylinders II 19 to open and close, and the lifting electric cylinders II 19 drive the lifting plate 4 to move up and down.

[0043] The translation mechanism includes a transverse guide rail 6 and a longitudinal guide rail 7. The transverse guide rail 6 is fixed on the lifting plate 4. The longitudinal guide rail 7 is movably located on the transverse guide rail 6 in the left-right direction. The placing plate 9 is movably located on the longitudinal guide rail 7 in the front-rear direction. A driving mechanism I is arranged on the lifting plate 4. The driving mechanism I drives the longitudinal guide rail 7 to move left and right along the transverse guide rail 6. A driving mechanism II is arranged on the longitudinal guide rail 7. The driving mechanism II drives the placing plate 9 to move back and forth along the longitudinal guide rail 7.

[0044] The slider 12 mechanism includes a slider 12. The slider 12 moves along the arc-shaped frame 11. A rotating plate 16 is arranged on the front side of the slider 12. The rotating plate 16 can rotate relative to the slider 12. A support frame 17 is arranged on the rotating plate 16. A rotating block 18 is rotatably arranged on the support frame 17. An infrared light-sensitive camera 15 is arranged on the rotating block 18.

[0045] A method for cardiopulmonary monitoring. The method for using the cardiopulmonary monitor is based on the non-contact cardiopulmonary monitor for experimental animals under anesthesia.

[0046] Including step S1: Place the animal to be monitored after anesthesia on the cardiopulmonary monitor, and stick the reflective sticker on the heart or chest part of the experimental animal, and keep the reflective sticker placed horizontally.

[0047] S11: Mark the reflective sticker on the detection part of the animal to be detected through the position determination mechanism.

[0048] S12: The position determination mechanism transmits the measured position information to the controller. The controller controls the infrared light-sensitive camera 15, the infrared thermal imaging sensor 14, and the infrared laser tube 13 to move to the specified position, so as to realize that the infrared laser tube 13 irradiates on the reflective sticker to form an incident and reflected light path, and the infrared light-sensitive camera 15 receives the reflected light path.

[0049] S2: Generate a thermal map warning in real time through the infrared thermal imaging sensor.

[0050] S3: Infrared laser irradiates the reflective sticker attached to the chest or heart of the experimental animal, and the camera collects the emitted laser to generate a respiratory waveform diagram in real-time analysis; the respiratory waveform diagram obtained through analysis is used as a respiratory warning. The lens of the infrared thermal imaging sensor 14 is perpendicular to the reflective sticker to photograph the whole body of the animal or the heart or chest of the animal, and the infrared thermal imaging sensor 14 generates a heat map warning in real-time;

[0051] S4: Based on the parameters of the heat map and the respiratory waveform diagram, judge the final vital sign parameters of the animal in the experiment to monitor whether the animal is in life danger.

[0052] The position determination mechanism is the indicator light mechanism 1 8 and the indicator light mechanism 2 5. The initial positions of the indicator light mechanism 1 8, the indicator light mechanism 2 5 and the lifting plate arc-shaped frame are set in advance, and the controller calculates them. Furthermore, the position information of the part to be detected of the animal and the overall equipment can be adjusted by the change of the position measured by the position determination mechanism, and automatic position monitoring, etc. can be realized.

[0053] When the present invention is used, the anesthetized animal to be monitored is placed on the cardiopulmonary monitor, and the reflective sticker is attached to the heart or chest of the experimental animal and kept horizontally placed to prevent the reflected light irradiated on the reflective sticker from not being received by the infrared sensitive camera 15.

[0054] The reflective sticker on the part to be detected of the animal is marked by the position determination mechanism.

[0055] The position is measured by the position determination mechanism, that is, the position of the reflective sticker is cross-marked by the indicator light mechanism 1 8 and the indicator light mechanism 2 5. At the same time, the indicator light mechanism 1 8 and the indicator light mechanism 2 5 can move up and down to realize the up and down movement of the indicator light, and the corresponding height of the up and down position of the reflective sticker can be realized. The indicator light emitted by the indicator light mechanism is a horizontal light. At the same time, move the indicator light mechanism 1 8 and the indicator light mechanism 2 5 to realize the vertical cross-marking of the position of the reflective sticker. The up and down height of the position of the reflective sticker relative to the bottom plate 1 is recorded by the up and down movement of the indicator light mechanism, and the horizontal position information of the reflective sticker on the bottom plate 1 can be obtained through the horizontal movement positions of the two indicator light mechanisms.

[0056] The position determination mechanism transmits the measured position information to the controller. After the controller obtains the position information, it controls the translation mechanism to move and place the marked position at the middle position of the bottom plate 1, that is, the movement of the marked position is realized by controlling the drive mechanism 1 and the drive mechanism 2 in the translation mechanism.

[0057] That is, when the translation mechanism drives the marked position to move horizontally, the driving mechanism 1 is controlled to drive the longitudinal guide rail 7 to move left and right along the transverse guide rail 6, and the driving mechanism 2 is controlled to drive the placement plate 9 to move back and forth along the longitudinal guide rail 7, so as to realize the horizontal movement of the marked position, and place the marked position in the middle of the bottom plate 1, which is convenient for the subsequent movement of the infrared laser tube 13 and the infrared sensitive camera 15 on the arc-shaped frame 11 to always keep the irradiation position and the receiving position unchanged.

[0058] At the same time, the controller controls the lifting mechanism to lift the height of the marked position, and at the same time cooperates with the lifting mechanism to drive the arc-shaped frame 11 to move up and down, and adjusts the height of the marked position to the center position of the arc-shaped frame 11, which is convenient for the infrared laser tube 13 and the infrared sensitive camera 15 to always keep the irradiation position and the receiving position unchanged when moving on the arc-shaped frame 11.

[0059] That is, when the lifting mechanism drives the marked position to move up and down, the telescopic movement of the lifting electric cylinder 2 is controlled to drive the folding plate 21 to expand and fold, and then drive the lifting plate 4 to move up and down, so as to realize the up and down movement of the marked position on the placement plate 9; when the lifting mechanism moves up and down, the telescopic movement of the lifting electric cylinder 1 is controlled to drive the lifting cylinder 10 to move up and down, so as to realize the up and down movement of the arc-shaped frame 11.

[0060] Then, the driving mechanism 3 is controlled to drive the lifting mechanism to move back and forth, that is, the driving mechanism 3 drives the guide rod 3 to rotate, and then drives the fixed cylinder 2 to move back and forth, so as to realize the back and forth movement of the lifting mechanism, so that the irradiation and receiving positions of the infrared laser tube 13 and the infrared sensitive camera 15 correspond to the reflective stickers.

[0061] The controller controls the infrared sensitive camera 15, the infrared thermal imaging sensor 14, and the infrared laser tube 13 to move to the specified positions, so as to realize the formation of incident and reflected light paths by irradiating the reflective stickers with the infrared laser tube 13, the infrared sensitive camera 15 receives the reflected light path, and the breathing waveform diagram is obtained through analysis as a breathing warning. The lens of the infrared thermal imaging sensor 14 is perpendicular to the reflective sticker to photograph the whole body of the animal or the heart or chest of the animal. The infrared thermal imaging sensor 14 generates a thermal map warning in real time; based on the thermal map and the breathing waveform diagram parameters, the final vital sign parameters of the animal in the experiment are judged to monitor whether the animal is in life danger. The determination of the thermal map and the breathing waveform diagram parameters is the prior art and will not be described in detail technically. As long as the functions required by this application can be realized.

[0062] When it is necessary to change the irradiation angle or the light receiving angle of the infrared laser tube 13 and the infrared sensitive camera 15 on the reflective sticker, the driving mechanism 4 arranged on the slider 12 is used to drive the slider 12 to move along the arc-shaped frame 11. Specifically, the technical solution of the driving mechanism 4 and driving the slider 12 to move is not technically limited. As long as the movement can be realized, it is the prior art.

[0063] When it is necessary to adjust or finely adjust the positions of the infrared laser tube 13, the infrared sensitive camera 15, and the infrared thermal imaging sensor 14, the rotation of the support frame 17 can be achieved by rotating the rotating plate 16, thereby driving the rotating block 18 to rotate. Moreover, the rotating block 18 can be rotated to adjust the angle of the rotating block 18 relative to the slider 12, and then the rotation angles of the infrared laser tube 13, the infrared sensitive camera 15, and the infrared thermal imaging sensor 14 can be adjusted, so as to achieve the adjustment of their positions. The driving method and connection structure of the rotation of the rotating block 18 and the support frame 17 are not technically limited, as long as the position adjustment function required by this application can be achieved, which is the prior art. The infrared laser tube 13, the infrared sensitive camera 15, and the infrared thermal imaging sensor 14 are the prior art and will not be described in detail technically. Moreover, the realization of the functions of the above-mentioned infrared laser tube 13, infrared sensitive camera 15, and infrared thermal imaging sensor 14 is the prior art and will not be described in detail technically.

[0064] In addition, when the left semiconductor infrared laser emitter emits a beam of light, the light is focused through the emitter lens to make the light become concentrated and form a dot, and finally irradiates on the reflective sticker attached to the animal. The up and down fluctuations of the reflective sticker will change the change of the light spot captured by the infrared sensitive camera 15, forming a position difference into a data difference and transmitting it to the controller. The controller analyzes the change amplitude of the up and down position of the reflective sticker to control the infrared sensitive camera 15 to move along the arc-shaped frame 11 (or the infrared laser tube 13) to ensure that the emission and reception of light by the infrared laser tube 13 and the infrared sensitive camera 15 reach the best effect; or the controller adjusts the up and down height of the arc-shaped frame 11 or adjusts the height of the placement plate 9 through the lifting mechanism or adjusts the lifting position of the placement plate 9 through the lifting and lowering mechanism; the beam emitted by the semiconductor laser irradiates on the target, and the receiver lens gathers the light reflected by the target and focuses it on the photosensitive element. When the distance from the target changes, the angle of the reflected light passing through the infrared sensitive camera 15 will also change accordingly, and the light is focused at a position on the infrared sensitive camera 15.

[0065] The above functions of controlling and timely adjusting each electrical component through the controller are the prior art and will not be described in detail technically, as long as the functions required by this application can be achieved; what this application mainly protects is this application of the device and the non-contact monitoring method for automatically realizing the cardiopulmonary monitoring of animals by this device.

[0066] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention.

[0067] The above are only the preferred embodiments of the present invention, and are not intended to limit the present invention. For those skilled in the art, the present invention may have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A contactless cardiopulmonary monitor for experimental animals under anesthesia, comprising a bottom plate, characterized in that: A placing plate is arranged on the bottom plate, an arc frame is arranged on the bottom plate and can be moved forward and backward, three slider mechanisms are arranged on the arc frame, the slider mechanisms can move along the arc frame, and an infrared photosensitive camera, an infrared thermal imaging sensor, and an infrared laser tube are arranged on the slider mechanisms from left to right respectively; an indicator light mechanism 1 and an indicator light mechanism 2 are arranged on the bottom plate, the indicator light mechanism 1 can move left and right along the bottom plate, the indicator light mechanism 2 can move forward and backward along the bottom plate, the indicator light mechanism 1 and the indicator light mechanism 2 have the same structure, the indicator light mechanism 1 includes a lifting rod, an indicator light is arranged on the upper end of the lifting rod, and the lifting rod can drive the indicator light to move up and down.

2. According to claim 1, a non-contact cardiopulmonary monitor for experimental animals under anesthesia, characterized in that: A lifting mechanism and a translation mechanism are arranged between the placement plate and the bottom plate. The lifting mechanism is arranged on the bottom plate, and a translation mechanism is arranged above the lifting mechanism. The lifting mechanism drives the translation mechanism to move up and down. The prevention plate is arranged on the translation mechanism, and the translation mechanism drives the placement plate to move horizontally.

3. According to claim 1, a non-contact cardiopulmonary monitor for experimental animals under anesthesia, characterized in that: A lifting mechanism is arranged between the arc frame and the bottom plate, and a lifting mechanism is arranged at the bottom of the left and right sides of the arc frame respectively, and the lifting mechanism drives the arc frame to move up and down.

4. A contactless cardiopulmonary monitor for experimental animals under anesthesia according to claim 3, characterized in that: The lifting mechanism includes a fixed cylinder, a lifting cylinder is arranged in the fixed cylinder and can move up and down, the upper end of the lifting cylinder is connected to the bottom of the arc frame, a lifting electric cylinder is arranged between the lifting cylinder and the fixed cylinder, and the lifting electric cylinder drives the lifting cylinder to move up and down.

5. A contactless cardiopulmonary monitor for experimental animals under anesthesia according to claim 4, characterized in that: Two guide rods are symmetrically arranged between the lifting mechanism and the base plate. The guide rods are rotatably arranged on the base plate. The lower part of the fixed cylinder is movably arranged on the guide rods. The fixed cylinder and the guide rods are threadedly connected. A driving mechanism three is arranged on the base plate at one end of each guide rod, and the driving mechanism three drives the guide rod to rotate.

6. A cardiopulmonary monitoring method, characterized in that: The method for using the cardiopulmonary monitor is based on the contactless cardiopulmonary monitor for experimental animals under anesthesia as described in any one of claims 1 to 5, The method comprises step S1: placing the anesthetized animal to be monitored on a cardiopulmonary monitor, attaching a reflective sticker to the heart or chest of the experimental animal, and keeping the reflective sticker horizontally; S2: Generates thermal map warning in real time through infrared thermal imaging sensor; S3: infrared laser irradiates the reflective sticker attached to the chest or heart of the experimental animal, and the camera collects the emitted laser for real-time analysis to generate a respiratory waveform; S4: Based on the parameters of the thermogram and respiratory waveform, the final vital sign parameters of the animals in the experiment are determined to monitor whether the animals are in danger of life.

7. A cardiopulmonary monitoring method according to claim 6, characterized in that: The step S1 comprises: S11: The reflective stickers of the detection parts of the animal to be detected are marked by a position determination mechanism; S12: The position measuring mechanism transmits the measured position information to the controller, and the controller controls the infrared camera, the infrared thermal imaging sensor, and the infrared laser tube to move to the specified position, so that the infrared laser tube irradiates the reflective tape to form an incident and reflected light path, and the infrared camera receives the reflected light path.

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