Chinese herbal medicine formula for preventing diarrhea of rabbits and preparation method of Chinese herbal medicine formula

Abstract

The invention belongs to the technical field of rabbit diarrhea treatment, and particularly relates to a Chinese herbal medicine formula for preventing rabbit diarrhea and a preparation method thereof, the Chinese herbal medicine formula comprises 10-15 parts of plantain herb, 5-10 parts of dandelion, 15-20 parts of mugwort, 10-15 parts of artemisia scoparia, 9-12 parts of oriental wormwood, 5-10 parts of wild chrysanthemum, 10-20 parts of purslane, 5-10 parts of isatis root, 6-12 parts of polygonum aviculare, 15-25 parts of poria cocos, and 5-15 parts of licorice. The traditional Chinese medicine composition is prepared according to the principle of monarch, minister, assistant and guide and is combined with a modern method, so that the traditional Chinese medicine composition is better in effect, is a pure traditional Chinese medicine product, is natural and free of medicine residues, ensures the medicine safety, is healthily taken by rabbits, has the effect of treating diarrhea and the effect of expelling parasites, and is suitable for being taken by rabbits. The practicability of the medicine is further enhanced.

Description

Technical Field

[0001] The present invention relates to the technical field of treating rabbit diarrhea, and specifically to a traditional Chinese medicine formula for preventing rabbit diarrhea and its preparation method. Background Art

[0002] Rabbit diarrhea is one of the common diseases in rabbit breeding, which seriously affects the health and production performance of rabbits. Traditional treatment methods mostly use chemical drugs, but long-term use is likely to produce drug resistance and there may be problems of drug residues. Therefore, developing a safe, efficient and drug-resistant traditional Chinese medicine formula and its preparation method is of great significance for preventing rabbit diarrhea.

[0003] Publication No. CN103356781A discloses a traditional Chinese medicine composition for treating coccidial diarrhea in rabbits and its preparation method. Among them, the two traditional Chinese medicine materials, Coptis chinensis and Phellodendron amurense, although they are traditional Chinese medicines, contain a large amount of pigments and alkaloids, and are likely to produce drug residues when used, thus affecting the health of rabbits. Summary of the Invention

[0004] In view of the deficiencies of the prior art, the present invention provides a traditional Chinese medicine formula for preventing rabbit diarrhea and its preparation method to solve the problems raised in the above background art.

[0005] To achieve the above object, the present invention provides the following technical solution: A traditional Chinese medicine formula for preventing rabbit diarrhea and its preparation method, which is composed of the following components in parts by weight: Plantago asiatica: 10 - 15 parts, Taraxacum mongolicum: 5 - 10 parts, Artemisia argyi: 15 - 20 parts, Artemisia scoparia: 10 - 15 parts, Artemisia capillaris: 9 - 12 parts, Chrysanthemum indicum: 5 - 10 parts, Portulaca oleracea: 10 - 20 parts, Isatis indigotica: 5 - 10 parts, Polygonum aviculare: 6 - 12 parts, Poria cocos: 15 - 25 parts, Glycyrrhiza uralensis: 5 - 15 parts; The preparation method of the traditional Chinese medicine at least includes the following steps:

[0006] Step 1: Wash Plantago asiatica, Taraxacum mongolicum, Artemisia argyi, Artemisia scoparia, Artemisia capillaris, Chrysanthemum indicum, Isatis indigotica, Polygonum aviculare, Poria cocos and Glycyrrhiza uralensis, dry or bake them and then crush them into fine powder;

[0007] Step 2: Weigh the crushed traditional Chinese medicine fine powder according to the ratio and mix it evenly;

[0008] Step 3: Decoct the mixed medicinal materials with slow fire for 0.7 - 1.2 hours to obtain a decoction;

[0009] Step 4: Package the decoction, 30 ml per bag, and give one bag to the rabbit each time, twice a day.

[0010] As a preferred technical solution of the present invention, it is composed of the following components in parts by weight: Plantain: 13 parts, Dandelion: 7 parts, Mugwort: 17 parts, Artemisia scoparia Waldst. & Kit.: 15 parts, Artemisia capillaris Thunb.: 10 parts, Wild Chrysanthemum: 7 parts, Purslane: 15 parts, Isatis root: 7 parts, Polygonum aviculare L.: 7 parts, Poria cocos (Schw.) Wolf: 18 parts, Licorice: 12 parts.

[0011] As a preferred technical solution of the present invention, the purslane can be directly ground into powder and mixed into the decoction, or the fresh purslane can be chopped and directly fed to rabbits.

[0012] As a preferred technical solution of the present invention, the grinding in step 1 is to grind to pass through an 80-100 mesh sieve.

[0013] The medicinal properties of the traditional Chinese medicine raw materials used in the present invention are as follows:

[0014] Plantain: Cold in nature, sweet in taste, belonging to the liver, kidney, lung, and small intestine meridians, having the effects of clearing heat and promoting diuresis, promoting dampness and relieving diarrhea, improving eyesight, and resolving phlegm.

[0015] Dandelion: Cold in nature, sweet and bitter in taste, belonging to the liver and stomach meridians, having the effects of clearing heat and detoxifying, dissipating swelling and nodules, and promoting diuresis and relieving stranguria.

[0016] Mugwort: Warm in nature, pungent and bitter in taste, belonging to the liver, spleen, and kidney meridians, having the effects of warming the meridian and stopping bleeding, dispelling cold and relieving pain, and removing dampness and relieving itching.

[0017] Artemisia scoparia Waldst. & Kit.: Cold in nature, bitter in taste, belonging to the liver and gallbladder meridians, having the effects of clearing heat and relieving summer heat, intercepting malaria, and cooling blood. However, it should be noted that there is a difference in cold and warm properties between Artemisia scoparia Waldst. & Kit. and Mugwort. If they need to be used simultaneously, they should be carefully combined according to the patient's constitution and condition.

[0018] Artemisia capillaris Thunb.: Slightly cold in nature, bitter and pungent in taste, belonging to the spleen, stomach, liver, and gallbladder meridians, having the effects of clearing and promoting dampness-heat, and promoting bile drainage and relieving jaundice.

[0019] Wild Chrysanthemum: Slightly cold in nature, bitter and pungent in taste, belonging to the liver and heart meridians, having the effects of clearing heat and detoxifying, and purging fire and calming the liver.

[0020] Isatis root: Cold in nature, bitter in taste, belonging to the heart and stomach meridians, having the effects of clearing heat and detoxifying, and cooling blood and relieving sore throat.

[0021] Polygonum aviculare L.: Slightly cold in nature, bitter in taste, belonging to the bladder meridian, having the effects of promoting diuresis and relieving stranguria, and killing parasites and relieving itching.

[0022] Poria cocos (Schw.) Wolf: Neutral in nature, sweet and light in taste, belonging to the heart, lung, spleen, and kidney meridians, having the effects of promoting diuresis and percolating dampness, strengthening the spleen and calming the heart.

[0023] Licorice: Neutral in nature, sweet in taste, belonging to the heart, lung, spleen, and stomach meridians, having the effects of invigorating the spleen and replenishing qi, clearing heat and detoxifying, resolving phlegm and relieving cough, relieving spasm and pain, and coordinating the properties of various drugs.

[0024] Compared with the prior art, the present invention provides a traditional Chinese medicine formula for preventing rabbit diarrhea and its preparation method, which has the following beneficial effects:

[0025] In this invention, the formula is made according to the principle of monarch, minister, assistant and envoy, and combined with modern methods, making the product of the present invention have better effects. The product of the present invention is a pure traditional Chinese medicine product, which is natural, drug residue-free, ensures drug safety, allows rabbits to take it healthily. At the same time, the present invention not only has the effect of treating diarrhea, but also has the function of expelling worms, further enhancing the practicability of the drug. Specific Embodiments

[0026] The following will combine the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.

[0027] Embodiment

[0028] The present invention provides the following technical solutions: a traditional Chinese medicine formula for preventing rabbit diarrhea and its preparation method, which is composed of the following components in parts by weight: Plantago asiatica: 10 - 15 parts, Taraxacum mongolicum: 5 - 10 parts, Artemisia argyi: 15 - 20 parts, Artemisia scoparia: 10 - 15 parts, Artemisia capillaris: 9 - 12 parts, Chrysanthemum indicum: 5 - 10 parts, Portulaca oleracea: 10 - 20 parts, Isatis indigotica: 5 - 10 parts, Polygonum aviculare: 6 - 12 parts, Poria cocos: 15 - 25 parts, Glycyrrhiza uralensis: 5 - 15 parts; The preparation method of the traditional Chinese medicine at least includes the following steps:

[0029] Step 1: Wash Plantago asiatica, Taraxacum mongolicum, Artemisia argyi, Artemisia scoparia, Artemisia capillaris, Chrysanthemum indicum, Isatis indigotica, Polygonum aviculare, Poria cocos and Glycyrrhiza uralensis, dry or bake them and then crush them into fine powder;

[0030] Step 2: Weigh the crushed traditional Chinese medicine fine powder according to the ratio and mix it evenly;

[0031] Step 3: Decoct the mixed medicinal materials with slow fire for 0.7 - 1.2 hours to obtain a decoction;

[0032] Step 4: Package the decoction, 30 ml per bag, and give one bag to the rabbit each time, twice a day.

[0033] Specifically, it is composed of the following components in parts by weight: Plantago asiatica: 13 parts, Taraxacum mongolicum: 7 parts, Artemisia argyi: 17 parts, Artemisia scoparia: 15 parts, Artemisia capillaris: 10 parts, Chrysanthemum indicum: 7 parts, Portulaca oleracea: 15 parts, Isatis indigotica: 7 parts, Polygonum aviculare: 7 parts, Poria cocos: 18 parts, Glycyrrhiza uralensis: 12 parts.

[0034] Specifically, the purslane is directly crushed into dry powder and then mixed into the decoction, or the fresh purslane is chopped and directly fed to rabbits.

[0035] Specifically, the crushing in step 1 is to crush to pass through an 80-100 mesh sieve.

[0036] Example 1: A traditional Chinese medicine formula for preventing diarrhea in rabbits, and its preparation method is as follows:

[0037] (1) Plantain: 12 parts, Dandelion: 8 parts, Wormwood: 15 parts, Artemisia scoparia: 15 parts, Artemisia capillaris:

[0038] 9 parts, Wild chrysanthemum: 8 parts, Purslane: 12 parts, Isatis root: 6 parts, Polygonum aviculare: 9 parts, Poria: 19 parts, Licorice: 8 parts.

[0039] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, artemisia capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria and licorice, dry or bake them and then crush them into fine powder. Weigh the crushed traditional Chinese medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 0.9 hours to obtain a decoction.

[0040] Example 2: A traditional Chinese medicine formula for preventing diarrhea in rabbits, and its preparation method is as follows:

[0041] (1) Plantain: 11 parts, Dandelion: 10 parts, Wormwood: 20 parts, Artemisia scoparia: 12 parts, Artemisia capillaris:

[0042] 12 parts, Wild chrysanthemum: 8 parts, Purslane: 15 parts, Isatis root: 8 parts, Polygonum aviculare: 7 parts, Poria: 15 parts, Licorice: 13 parts.

[0043] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, artemisia capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria and licorice, dry or bake them and then crush them into fine powder. Weigh the crushed traditional Chinese medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 1 hour to obtain a decoction.

[0044] Example 3: A traditional Chinese medicine formula for preventing diarrhea in rabbits, and its preparation method is as follows:

[0045] (1) Plantain: 13 parts, Dandelion: 7 parts, Wormwood: 17 parts, Artemisia scoparia: 13 parts, Artemisia capillaris:

[0046] 10 parts, Wild chrysanthemum: 8 parts, Purslane: 11 parts, Isatis root: 8 parts, Polygonum aviculare: 9 parts, Poria: 16 parts, Licorice: 12 parts.

[0047] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria cocos and liquorice, dry them in the sun or by baking, then crush them into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 1.2 hours to obtain the decoction.

[0048] Example 4: A Chinese herbal medicine formula for preventing rabbit diarrhea, and its preparation method is as follows:

[0049] (1) Plantain: 15 parts, dandelion: 9 parts, wormwood: 18 parts, artemisia scoparia: 12 parts, capillaris: 10 parts, wild chrysanthemum: 8 parts, purslane: 13 parts, isatis root: 8 parts, polygonum aviculare: 11 parts, poria cocos 21 parts, liquorice 9 parts.

[0050] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria cocos and liquorice, dry them in the sun or by baking, then crush them into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 1.1 hours to obtain the decoction.

[0051] Example 5: A Chinese herbal medicine formula for preventing rabbit diarrhea, and its preparation method is as follows:

[0052] (1) Plantain: 13 parts, dandelion: 7 parts, wormwood: 17 parts, artemisia scoparia: 13 parts, capillaris: 10 parts, wild chrysanthemum: 8 parts, purslane: 16 parts, isatis root: 8 parts, polygonum aviculare: 11 parts, poria cocos 19 parts, liquorice 11 parts.

[0053] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria cocos and liquorice, dry them in the sun or by baking, then crush them into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 0.85 hours to obtain the decoction.

[0054] Example 6: A Chinese herbal medicine formula for preventing rabbit diarrhea, and its preparation method is as follows:

[0055] (1) Plantain: 15 parts, dandelion: 10 parts, wormwood: 15 parts, artemisia scoparia: 15 parts, capillaris: 11 parts, wild chrysanthemum: 8 parts, purslane: 13 parts, isatis root: 7 parts, polygonum aviculare: 10 parts, poria cocos 21 parts, liquorice 7 parts.

[0056] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria cocos and liquorice, dry them in the sun or by baking, then crush them into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 1.15 hours to obtain the decoction.

[0057] Example 7: A Chinese herbal medicine formula for preventing rabbit diarrhea, and its preparation method is as follows:

[0058] (1) Plantain: 13 parts, Dandelion: 7 parts, Wormwood: 17 parts, Artemisia scoparia: 13 parts, Capillary Wormwood: 10 parts, Wild Chrysanthemum: 8 parts, Purslane: 13 parts, Isatis Root: 5 parts, Awnless Bristlegrass: 8 parts, Poria: 19 parts, Licorice: 14 parts.

[0059] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, capillary wormwood, wild chrysanthemum, isatis root, awnless bristlegrass, poria and licorice, dry them in the sun or by baking, then crush them into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed herbs with slow fire for 0.8 hours to obtain the decoction.

[0060] Example 8: A Chinese herbal medicine formula for preventing rabbit diarrhea, and its preparation method is as follows:

[0061] (1) Plantain: 12 parts, Dandelion: 8 parts, Wormwood: 18 parts, Artemisia scoparia: 10 parts, Capillary Wormwood: 13 parts, Wild Chrysanthemum: 10 parts, Purslane: 20 parts, Isatis Root: 7 parts, Awnless Bristlegrass: 6 parts, Poria: 19 parts, Licorice: 10 parts.

[0062] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, capillary wormwood, wild chrysanthemum, isatis root, awnless bristlegrass, poria and licorice, dry them in the sun or by baking, then crush them into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed herbs with slow fire for 1.2 hours to obtain the decoction.

[0063] Example 9: A Chinese herbal medicine formula for preventing rabbit diarrhea, and its preparation method is as follows:

[0064] (1) Plantain: 10 parts, Dandelion: 7 parts, Wormwood: 16 parts, Artemisia scoparia: 11 parts, Capillary Wormwood: 9 parts, Wild Chrysanthemum: 5 parts, Purslane: 15 parts, Isatis Root: 7 parts, Awnless Bristlegrass: 9 parts, Poria: 20 parts, Licorice: 12 parts.

[0065] (2) Wash the plantain, dandelion, wormwood, artemisia scoparia, capillary wormwood, wild chrysanthemum, isatis root, awnless bristlegrass, poria and licorice, dry them in the sun or by baking, then crush them into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed herbs with slow fire for 0.78 hours to obtain the decoction.

[0066] Example 10: A Chinese herbal medicine formula for preventing rabbit diarrhea, and its preparation method is as follows:

[0067] (1) Plantain: 13 parts, Dandelion: 8 parts, Wormwood: 16 parts, Artemisia scoparia: 13 parts, Capillary Wormwood: 11 parts, Wild Chrysanthemum: 8 parts, Purslane: 13 parts, Isatis Root: 7 parts, Awnless Bristlegrass: 9 parts, Poria: 18 parts, Licorice: 12 parts.

[0068] (2) Wash plantain, dandelion, wormwood, artemisia scoparia, capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria cocos and liquorice, dry in the sun or by baking and then crush into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 1.05 hours to obtain the decoction.

[0069] Example 11: A Chinese herbal medicine formula for preventing diarrhea in rabbits, and its preparation method is as follows:

[0070] (1) Plantain: 15 parts, dandelion: 5 parts, wormwood: 20 parts, artemisia scoparia: 15 parts, capillaris: 9 parts, wild chrysanthemum: 10 parts, purslane: 10 parts, isatis root: 10 parts, polygonum aviculare: 12 parts, poria cocos 25 parts, liquorice 15 parts.

[0071] (2) Wash plantain, dandelion, wormwood, artemisia scoparia, capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria cocos and liquorice, dry in the sun or by baking and then crush into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 0.85 hours to obtain the decoction.

[0072] Example 12: A Chinese herbal medicine formula for preventing diarrhea in rabbits, and its preparation method is as follows:

[0073] (1) Plantain: 11 parts, dandelion: 8 parts, wormwood: 15 parts, artemisia scoparia: 13 parts, capillaris: 11 parts, wild chrysanthemum: 8 parts, purslane: 13 parts, isatis root: 8 parts, polygonum aviculare: 9 parts, poria cocos 25 parts, liquorice 14 parts.

[0074] (2) Wash plantain, dandelion, wormwood, artemisia scoparia, capillaris, wild chrysanthemum, isatis root, polygonum aviculare, poria cocos and liquorice, dry in the sun or by baking and then crush into fine powder. Weigh the crushed Chinese herbal medicine fine powder according to the ratio, mix evenly, and decoct the mixed medicinal materials with slow fire for 0.95 hours to obtain the decoction.

[0075] Experimental Example

[0076] (1) Materials and methods (1.1) Materials

[0077] The drugs of Example 1, Example 2, Example 3, Example 4, Example 5, Example 6, Example 7, Example 8, Example 9, Example 10, Example 11, and Example 12 of the present invention.

[0078] (1.2) Experimental animals and their grouping (1.2.1) A total of 120 rabbits, 40 to 50 days old and showing diarrhea symptoms, were selected as the research subjects. These rabbits were listless, preferred to be alone and were reluctant to eat. In severe cases, they completely lost their appetite. Their feces were soft, thin, in a thin paste or watery state, with a foul smell, and their abdomens were significantly distended. In addition, the body temperature of the rabbits increased, their fur became rough and lost its luster, and cyanosis or jaundice might appear in the conjunctiva. These rabbits were evenly divided into 4 groups, with 30 rabbits in each group. The drug was administered by mixing it into the feed and continuously fed for 5 days. The daily feeding amount was equivalent to 100 grams of the original medicinal material.

[0079] (1.2.2) Evaluation of treatment effect

[0080] Recovery: The diarrhea symptoms disappeared and the rabbits ate normally.

[0081] Effective: The diarrhea effect was alleviated.

[0082] Ineffective: The symptoms did not improve or the rabbits died.

[0083] (2) Experimental results

[0084] The following table shows the treatment effect of the present invention on rabbit diarrhea

[0085]

[0086] Experimental results: Compared with the blank control group, the groups of Examples 1 - 3 of the present invention could effectively treat rabbit diarrhea and had good treatment effects.

[0087] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A Chinese herbal medicine formula for preventing diarrhea in rabbits and a preparation method thereof, characterized in that: The Chinese herbal medicine is composed of the following components in parts by weight: 10-15 parts of plantain, 5-10 parts of dandelion, 15-20 parts of mugwort, 10-15 parts of artemisia annua, 9-12 parts of capillaris, 5-10 parts of wild chrysanthemum, 10-20 parts of purslane, 5-10 parts of isatis root, 6-12 parts of scutellaria baicalensis, 15-25 parts of tuckahoe, and 5-15 parts of licorice. The preparation method of the Chinese herbal medicine comprises at least the following steps: Step 1: Wash plantain, dandelion, mugwort, wormwood, capillaris, wild chrysanthemum, isatis root, radix polygoni multiflori, poria and licorice, dry them in the sun or in the oven, and then grind them into fine powder; Step 2: Weigh the crushed Chinese herbal medicine powder according to the ratio and mix them evenly; Step 3: decocting the mixed medicinal materials over a slow fire for 0.7-1.2 hours to prepare a decoction; Step 4: Divide the decoction into 30 ml bags and give one bag to the rabbit twice a day.

2. A Chinese herbal medicine prescription for preventing diarrhea in rabbits and a preparation method thereof according to claim 3, characterized in that: The invention is composed of the following components in parts by weight: 13 parts of plantain, 7 parts of dandelion, 17 parts of mugwort, 15 parts of wormwood, 10 parts of capillaris, 7 parts of wild chrysanthemum, 15 parts of purslane, 7 parts of isatis root, 7 parts of polypore, 18 parts of tuckahoe and 12 parts of liquorice.

3. A Chinese herbal medicine prescription for preventing diarrhea in rabbits according to claim 1 and a preparation method thereof, characterized in that: The dry product of purslane is directly ground into powder and then mixed into the water decoction.

4. A Chinese herbal medicine prescription for preventing diarrhea in rabbits and a preparation method thereof according to claim 2, characterized in that: The pulverization in step 1 is pulverizing until it passes through a 80-100 mesh sieve.

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