Ethnic medicine composition for detoxifying and relieving itching as well as preparation method and application of ethnic medicine composition
Through an ethnic pharmaceutical composition containing a variety of traditional Chinese medicine ingredients, the adverse reactions and drug resistance of biological agents in the treatment of skin diseases are solved, and the effects of detoxification and anti-itchiness and reducing recurrence are achieved, and the safety and effectiveness of treatment are improved.
Patent Information
- Application Number
- CN202510354396.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-25
- Publication Date
- 2025-06-17
AI Technical Summary
When existing biological agents are used to treat skin diseases, adverse reactions such as local allergies, inflammation, drug resistance often occur, and the long-term use risk is high, making it difficult to effectively solve the recurrence of skin diseases.
A national medicinal composition is adopted to detoxify and relieve itching, including Astragalus, Angelica, Honeysuckle, Licorice, Black Plum, Schisandra chinensis, White Fresh Broth, Ganoderma lucidum, Wind-proof, Purple Grass, Curcuma zedo, White Peony, Bupleurum, Rhodiola, Rhodiola, Saffron, and Ole Glycyrrhiza. Through the treatment method of internal and external combination, the yin and yang balance of the human body is regulated, the physique is improved, and the lesions are directly applied to reduce systemic side effects.
This ethnic medicine composition has multiple functions of invigorating Qi and supporting toxicity, clearing heat and detoxifying, drying dampness and relieving itching, relieving wind and dispersing evil, significantly improving patients' discomfort symptoms, reducing the risk of recurrence of skin diseases, and improving treatment experience and compliance.
Abstract
Description
Technical Field
[0001] The present invention belongs to the field of ethnic medicine preparations, and relates to an ethnic medicine composition for detoxifying and relieving itching, and specifically relates to an ethnic medicine composition for detoxifying and relieving itching, a preparation method and an application thereof. Background Art
[0002] Skin diseases pose multiple harms to patients. They not only affect skin health, but may also involve multiple systems and organs throughout the body, and even endanger life. Therefore, sufficient attention and timely treatment should be given to patients with skin diseases. Currently, the commonly used clinical agents are biological agents, and there are often many adverse reactions to biological agents: local allergies, inflammation, drug resistance, etc. These include erythema, itching, pain, swelling, etc. In severe cases, it will lead to a decline in the body's immune ability, increase the risk of infection, cause inflammatory reactions in patients, and cause obvious side effects to the body. When using biological agents to treat skin diseases, the problem of drug resistance in patients will occur, which is generally more obvious after 1-2 years of treatment.
[0003] Ethnic medicine has unique advantages and characteristics in the treatment of skin diseases. Combining traditional theories and clinical practices, its advantages are mainly reflected in the following aspects:
[0004] 1. Overall conditioning, treating both the symptoms and the root causes: Ethnic medicine emphasizes the concept of wholism. Skin diseases are not only local problems, but are often related to disorders of internal organ functions, disharmony of qi and blood, or invasion of exogenous pathogens. Ethnic medicine reduces the recurrence of skin diseases from the root by regulating the balance of yin and yang in the human body and improving the physique, and at the same time improves the internal environment rather than simply suppressing surface symptoms.
[0005] 2. Fewer side effects and higher safety: Natural medicines, mild effects: Most ethnic medicines are composed of natural plant, mineral or animal ingredients. Compared with hormonal or immunosuppressive agents, they have less irritation and lower risks for long-term use.
[0006] 3. Treating both internally and externally, multi-pathway intervention: Combining internal administration and external application: Internal administration can regulate the physique, and external applications such as paints, medicated baths, ointments, and lotions can directly reduce inflammation and relieve itching, and promote the repair of skin lesions.
[0007] 4. Multi-target effects: Ethnic medicine compounds often contain multiple active ingredients (such as flavonoids, polysaccharides), and have comprehensive effects such as antibacterial, anti-inflammatory, and immunomodulatory effects.
[0008] 5. Outstanding advantages for chronic and recurrent diseases: Reducing recurrence: For diseases such as psoriasis, chronic eczema, and atopic dermatitis that recur frequently, ethnic medicine can prolong the remission period by regulating the immune system and improving microcirculation.
[0009] 6. Assisting in repairing the skin barrier: Promoting self-healing ability: For example, licorice and astragalus can enhance the skin's moisturizing function, repair the barrier, and reduce dryness and desquamation.
[0010] In summary, the core of ethnic medicine in treating skin diseases is "regulating the inside and treating the outside", and it has an absolute advantage in treating skin diseases. Ethnic medicine should be explored in depth to develop more promising innovative drugs. The present invention proposes an ethnic medicine composition for detoxification and antipruritic and its application, which has the comprehensive effects of invigorating qi and detoxifying, clearing away heat and detoxifying, drying dampness and relieving itching, and dispersing wind and evil. At the same time, it directly acts on the lesions through external application, reduces systemic side effects, and improves the patient's treatment experience and compliance. Summary of the invention
[0011] The object of the present invention is to provide a detoxifying and antipruritic ethnic medicine composition and its application, with Astragalus as the main ingredient, and Qi-invigorating, detoxifying, regenerating muscles and astringing sores as the core; in addition to the well-known effects of "tonifying blood and activating blood circulation, regulating menstruation and relieving pain, and moistening the intestines and relieving constipation", Angelica sinensis also treats carbuncle and ulcer; "Essentials of Herbal Medicine" records that honeysuckle can eliminate carbuncle and furuncle toxins, wash scurvy, and remove skin blood heat; the three act synergistically to play the role of Qi-invigorating and carbuncle-eliminating. Smilax glabra detoxifies, removes dampness, and benefits joints. Dictamni: dispels wind, dries dampness, clears heat, and detoxifies; treats wind-heat sores, scabies, skin pruritus, etc. Lithospermum officinale cools blood, activates blood circulation, clears heat, and detoxifies. Treats warm-heat macules, damp-heat jaundice, purpura, burns, eczema, erysipelas, and carbuncle. The three act synergistically to play the role of clearing heat and detoxifying, drying dampness and relieving itching. "Essentials of Herbal Medicine" records that Curcuma can be applied to sores to reduce swelling, dissipate blood stasis and relieve pain, and can also stop bleeding and treat trauma. Rhodiola rosea can invigorate qi, promote blood circulation and stop bleeding, and can be used externally to treat trauma, burns and scalds. Safflower can promote blood circulation and dredge menstruation, remove blood stasis and relieve pain, and is mainly used to treat pain caused by blood stasis and carbuncle. The three can be used together to promote blood circulation, remove blood stasis, stop bleeding and relieve pain. Ganoderma lucidum can invigorate qi and blood, calm the mind, and strengthen the spleen and stomach. White peony root nourishes blood and softens the liver, relieves pain, and restrains yin and sweat. The two work synergistically to play the role of replenishing qi and blood. Bupleurum harmonizes the exterior and interior, soothes the liver, and raises yang. "Ben Jing" records that black plum can reduce qi, remove heat and fullness, calm the mind, treat limb pain, hemiplegia, dead muscle, and remove blue and black moles and bad flesh. "New Compendium of Materia Medica" records that Schisandra chinensis can treat sores and ulcers, and those whose skin and flesh are about to fall off can be preserved by applying it. The two can be used together to improve symptoms. Saposhnikovia divaricata is a wind-dispelling and antipyretic drug, with a pungent and sweet taste and a slightly warm nature. It enters the spleen, liver, and bladder meridians, is good at dispelling wind and dampness, relieving itching and detoxifying, and can especially relieve local itching and skin allergic reactions of ulcers, relieve evil poison from the surface, and at the same time, as a meridian-guiding drug, it improves the overall synergy of the drug effects of the whole prescription. Licorice is in harmony with the middle to relieve urgency, moisten the lungs, detoxify, and harmonize various drugs. Phyllanthus emblica is sweet, pungent, and flat in nature, and is mainly used to treat edema, skin eczema and other diseases. The compatibility of the present invention embodies the traditional Chinese medical concept of "positive energy is stored inside, and evil cannot be done", clears heat while invigorating qi, supports poison on the basis of clearing heat, supports poison with drying dampness and astringes, dispels wind and dissipates heat in the process of removing dampness, takes both the symptoms and the root cause into consideration, and treats both inside and outside. The whole folk medicine compound as a whole has achieved the multiple effects of invigorating qi and supporting poison, clearing heat and detoxifying, drying dampness and stopping itching, and dispersing wind and dispersing evil.
[0012] In order to achieve the above technical objectives and the above technical effects, the present invention is implemented through the following technical solutions:
[0013] A traditional ethnic medicine composition for detoxification and relieving itching, comprising: Astragalus membranaceus, Angelica sinensis, Lonicera japonica, Glycyrrhiza uralensis, Prunus mume, Schisandra chinensis, Smilax glabra, Dictamnus dasycarpus Turcz., Ganoderma lucidum, Saposhnikovia divaricata, Lithospermum erythrorhizon, Curcuma zedoaria, Paeonia lactiflora, Bupleurum chinense, Rhodiola rosea, Carthamus tinctorius, Phyllanthus emblica.
[0014] Further, the raw material dosage ratio of the traditional ethnic medicine composition is: 10 - 20 parts of Astragalus membranaceus, 9 - 18 parts of Angelica sinensis, 9 - 18 parts of Lonicera japonica, 1 - 10 parts of Glycyrrhiza uralensis, 1 - 10 parts of Prunus mume, 1 - 10 parts of Schisandra chinensis, 5 - 15 parts of Smilax glabra, 1 - 10 parts of Dictamnus dasycarpus Turcz., 1 - 10 parts of Ganoderma lucidum, 1 - 10 parts of Saposhnikovia divaricata, 1 - 10 parts of Lithospermum erythrorhizon, 1 - 10 parts of Curcuma zedoaria, 1 - 5 parts of Paeonia lactiflora, 1 - 10 parts of Bupleurum chinense, 0.5 - 1.5 parts of Rhodiola rosea, 0.5 - 1.5 parts of Carthamus tinctorius, 0.5 - 1.5 parts of Phyllanthus emblica.
[0015] The dosage is in weight parts.
[0016] Further, the preparation method of the traditional ethnic medicine composition is characterized by comprising the following steps:
[0017] 1) Decoct the components of the traditional ethnic medicine to obtain a decoction, and concentrate the decoction;
[0018] 2) Centrifuge, sterilize, and subpackage the obtained concentrated liquid to obtain the pharmaceutical composition.
[0019] Further, the preparation method is characterized by adding 6 - 8 times the amount of water and soaking for 35 - 60 minutes.
[0020] Further, the preparation method is characterized by decocting for 1 - 2 hours and filtering with a gauze.
[0021] Further, it is characterized by decocting again, adding 4 - 6 times the amount of water, and decocting again for 25 - 45 minutes.
[0022] Further, it is characterized by concentrating to 1000 - 2000 ml.
[0023] Further, the centrifugation speed is 500g / 10min, 2000g / 20min, 3000g / 30min, 5000g / 30min.
[0024] Further, each time, select the original decoction close to body temperature for wet compress for 20 - 30 minutes, and give it two to three times a day according to the severity of skin reaction.
[0025] On the other hand, the present invention provides a traditional ethnic medicine product for detoxification and relieving itching, and the traditional ethnic medicine product is prepared from the above-mentioned traditional ethnic medicine composition.
[0026] Further, the medicine includes but is not limited to liniments, decoctions, ointments, tinctures, sprays and dressings.
[0027] On the other hand, the present invention provides the use of the above ethnic medicine composition in the preparation of an antidote and antipruritic drug.
[0028] Advantages of the present invention:
[0029] The present invention uses the ethnic medicine components Astragalus membranaceus, Angelica sinensis, Lonicera japonica, Glycyrrhiza uralensis, Prunus mume, Schisandra chinensis, Smilax glabra, Dictamnus dasycarpus, Ganoderma lucidum, Saposhnikovia divaricata, Lithospermum erythrorhizon, Curcuma zedoaria, Paeonia lactiflora, Bupleurum chinense, Rhodiola rosea, Carthamus tinctorius, Phyllanthus emblica to act together. The multi-components cooperate synergistically to enhance the efficacy of detoxifying and relieving itching, can significantly improve the discomfort symptoms of patients, and at the same time can improve the body function and pathology, tonify qi and blood, and take into account strengthening the healthy qi while dispelling pathogenic factors, providing a basis for the clinical use of the ethnic medicine composition. Specific embodiments
[0030] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without making creative efforts shall fall within the protection scope of the present invention.
[0031] Example 1
[0032] An ethnic medicine composition for detoxifying and relieving itching as described in this example includes: Astragalus membranaceus, Angelica sinensis, Lonicera japonica, Glycyrrhiza uralensis, Prunus mume, Schisandra chinensis, Smilax glabra, Dictamnus dasycarpus, Ganoderma lucidum, Saposhnikovia divaricata, Lithospermum erythrorhizon, Curcuma zedoaria, Paeonia lactiflora, Bupleurum chinense, Rhodiola rosea, Carthamus tinctorius, Phyllanthus emblica.
[0033] In this example, the raw materials of the ethnic medicine composition include: 15 parts of Astragalus membranaceus, 10 parts of Angelica sinensis, 10 parts of Lonicera japonica, 5 parts of Glycyrrhiza uralensis, 5 parts of Prunus mume, 5 parts of Schisandra chinensis, 7 parts of Smilax glabra, 5 parts of Dictamnus dasycarpus, 5 parts of Ganoderma lucidum, 5 parts of Saposhnikovia divaricata, 5 parts of Lithospermum erythrorhizon, 5 parts of Curcuma zedoaria, 1 part of Paeonia lactiflora, 5 parts of Bupleurum chinense, 1 part of Rhodiola rosea, 1 part of Carthamus tinctorius, 1 part of Phyllanthus emblica
[0034] The above raw materials are decocted for 1 hour, and the decoction stock solution at 35 - 40 °C is selected each time for wet compress for 20 - 30 minutes, and wet compress is given two to three times a day according to the severity of skin reaction.
[0035] Example 2
[0036] The ethnic medicine composition for treating chronic diseases described in this embodiment, the raw material dosage ratio of the ethnic medicine composition is: 10-20 parts of Astragalus membranaceus, 9-18 parts of Angelica sinensis, 9-18 parts of Lonicera japonica, 1-10 parts of Glycyrrhiza uralensis, 1-10 parts of Prunus mume, 1-10 parts of Schisandra chinensis, 5-15 parts of Smilax glabra, 1-10 parts of Dictamnus dasycarpus, 1-10 parts of Ganoderma lucidum, 1-10 parts of Saposhnikovia divaricata, 1-10 parts of Lithospermum erythrorhizon, 1-10 parts of Curcuma zedoaria, 1-5 parts of Paeonia lactiflora, 1-10 parts of Bupleurum chinense, 0.5-1.5 parts of Rhodiola rosea, 0.5-1.5 parts of Carthamus tinctorius, 0.5-1.5 parts of Phyllanthus emblica.
[0037] Example 3
[0038] This embodiment is for patients mainly with qi deficiency. For such patients, the wound surface does not heal for a long time, the surrounding skin is pale or cold, there is no obvious redness, swelling, heat or pain, and the patients are generally fatigued, with a sallow complexion, a pale tongue with a thin white coating, and a weak pulse. This is a typical manifestation of the traditional Chinese medicine "qi deficiency failing to control" syndrome type.
[0039] The ethnic medicine composition for treating chronic diseases described in this embodiment, the raw material dosage ratio of the ethnic medicine composition is: 20 parts of Astragalus membranaceus, 15 parts of Angelica sinensis, 5 parts of Lonicera japonica, 5 parts of Glycyrrhiza uralensis, 5 parts of Prunus mume, 5 parts of Schisandra chinensis, 7 parts of Smilax glabra, 5 parts of Dictamnus dasycarpus, 10 parts of Ganoderma lucidum, 5 parts of Saposhnikovia divaricata, 1 part of Lithospermum erythrorhizon, 5 parts of Curcuma zedoaria, 1 part of Paeonia lactiflora, 5 parts of Bupleurum chinense, 1.5 parts of Rhodiola rosea, 1 part of Carthamus tinctorius, 0.5 part of Phyllanthus emblica.
[0040] Focus on tonifying qi and blood, thereby accelerating wound healing. On the basis of the original formula, increase the dosage of Astragalus membranaceus from 15 parts to 20 parts, because Astragalus membranaceus has the effects of supplementing qi to expel toxins and promoting granulation and astringing sores, and its increased dosage can effectively improve the wound healing ability of patients with qi deficiency. Increase the dosage of Angelica sinensis from 10 parts to 15 parts, because Angelica sinensis can enrich blood and promote blood circulation, and its increased dosage can quickly improve the symptoms of blood deficiency and jointly accelerate wound healing. Increase the dosage of Ganoderma lucidum from 5 parts to 10 parts, because Ganoderma lucidum has the effects of benefiting qi and blood, calming the mind, and strengthening the spleen and stomach. Increase the dosage of Rhodiola rosea from 1 part to 1.5 parts, because Rhodiola rosea has the effect of supplementing qi and promoting blood circulation. At the same time, to avoid side effects on patients with qi deficiency caused by overly strong cold or heat-clearing drugs, the dosage of Lonicera japonica can be reduced from 10 parts to 5 parts, the dosage of Dictamnus dasycarpus can be reduced from 5 parts to 1 part, the dosage of Lithospermum erythrorhizon can be reduced from 5 parts to 1 part, and the dosage of Phyllanthus emblica can be reduced from 1 part to 0.5 part, weakening the intensity of heat-clearing and avoiding damage to the spleen and stomach of the patients and impairing the vital qi. The dosages of the remaining medicinal materials can remain unchanged. Such adjustments make the prescription generally tend to tonify deficiency and expel toxins, while taking into account a slight effect of clearing heat, detoxifying and drying dampness.
[0041] Example 4
[0042] For patients with the syndrome of accumulation of damp-heat toxin, manifested as red, swollen, hot and painful wounds, with a large amount of thick and sticky secretions, local burning sensation, accompanied by purulent secretions, red tongue with yellow and greasy coating, and slippery and rapid pulse, this is a typical TCM syndrome type of "damp-heat toxin accumulation".
[0043] The ethnic medicine composition for treating chronic diseases in this embodiment, the raw material dosage ratio of the ethnic medicine composition is: 10 parts of Astragalus membranaceus, 5 parts of Angelica sinensis, 12 parts of Lonicera japonica, 5 parts of Glycyrrhiza uralensis, 5 parts of Prunus mume, 5 parts of Schisandra chinensis, 10 parts of Smilax glabra, 7 parts of Dictamnus dasycarpus, 5 parts of Ganoderma lucidum, 5 parts of Saposhnikovia divaricata, 7 parts of Lithospermum erythrorhizon, 5 parts of Curcuma zedoaria, 1 part of Paeonia lactiflora, 5 parts of Bupleurum chinense, 1 part of Rhodiola rosea, 0.5 part of Carthamus tinctorius, 1.5 parts of Phyllanthus emblica.
[0044] Focus on clearing heat and detoxifying dampness in treatment, and at the same time take into account promoting blood circulation and dredging collaterals, and promoting wound metabolism. On the basis of the original formula, it is recommended to increase the dosage of Lonicera japonica from 10 parts to 12 parts, the dosage of Lithospermum erythrorhizon from 5 parts to 7 parts, and the dosage of Phyllanthus emblica from 1 part to 1.5 parts. Both Lonicera japonica and Lithospermum erythrorhizon are good at clearing heat and detoxifying, and can directly target the wound inflammatory reaction caused by damp-heat toxin; the dosage of Smilax glabra should also be increased from 7 parts to 10 parts, and Smilax glabra has good effects of detoxifying and promoting diuresis; in addition, the dosage of Dictamnus dasycarpus should also be increased from 5 parts to 7 parts, and Dictamnus dasycarpus has prominent effects of clearing heat and drying dampness, and can relieve the symptoms of wound redness and itching. The dosage of Angelica sinensis is reduced from 10 parts to 5 parts, and Angelica sinensis is pungent and warm in nature. The dosage of Carthamus tinctorius is reduced from 1 part to 0.5 part, while maintaining the effect of promoting blood circulation to remove stasis and relieve pain of Carthamus tinctorius, reducing its warm nature. The dosage of Astragalus membranaceus can be appropriately reduced, adjusted from 15 parts to 10 parts, making the whole formula pay more attention to dispelling pathogenic factors rather than strengthening healthy qi. The adjusted formula focuses on the intensity of clearing heat and drying dampness, and at the same time avoids the harm of large doses of cold drugs to patients. By enhancing the dampness-detoxifying effect of the drugs, it promotes the wound to dry, scab and heal quickly.
[0045] Example 5
[0046] For patients with severe damp-toxin, obvious wound exudation, accompanied by erosion and severe itching, they generally belong to the TCM syndrome type of "damp-toxin pouring downward", and the pathogenesis is that damp-toxin stagnates in the skin and the qi and blood circulation is not smooth.
[0047] The ethnic medicine composition for treating chronic diseases in this embodiment, the raw material dosage ratio of the ethnic medicine composition is: 10 parts of Astragalus membranaceus, 10 parts of Angelica sinensis, 15 parts of Lonicera japonica, 5 parts of Glycyrrhiza uralensis, 5 parts of Prunus mume, 5 parts of Schisandra chinensis, 15 parts of Smilax glabra, 10 parts of Dictamnus dasycarpus, 5 parts of Ganoderma lucidum, 5 parts of Saposhnikovia divaricata, 10 parts of Lithospermum erythrorhizon, 5 parts of Curcuma zedoaria, 1 part of Paeonia lactiflora, 5 parts of Bupleurum chinense, 1 part of Rhodiola rosea, 1 part of Carthamus tinctorius, 1 part of Phyllanthus emblica.
[0048] It is necessary to strengthen the effect of clearing heat, drying dampness and detoxifying, and at the same time focus on relieving the local symptoms of dampness and itching. On the basis of the original formula, the dosage of Smilax glabra should be increased from 7 parts to 15 parts, and the dosage of Dictamnus dasycarpus should be increased from 5 parts to 10 parts. Smilax glabra can detoxify and promote diuresis, while Dictamnus dasycarpus is strong in clearing heat and drying dampness and relieving itching. Moreover, both of them also have anti-fungal and anti-inflammatory effects, and are particularly suitable for patients with damp-toxin exudation; the dosage of Lonicera japonica is adjusted from 10 parts to 15 parts. Lonicera japonica can clear heat and detoxify, disperse wind-heat, and at the same time has a broad-spectrum antibacterial effect to enhance the effects of relieving wind and itching, and dispersing wind and clearing heat. The dosage of Lithospermum erythrorhizon is adjusted from 5 parts to 10 parts. Lithospermum erythrorhizon is cold in nature and has the effects of clearing heat and cooling blood, promoting blood circulation and detoxifying, and penetrating measles and eliminating macules. It is especially effective for blood heat and toxin excess, purple and black macules, unpenetrated measles, sores, eczema, and burns caused by fire and water. For such patients, since the healthy qi has not been significantly deficient, the dosage of Astragalus membranaceus can be maintained at 15 parts or reduced to 10 parts to avoid promoting dampness and stagnating pathogens. Through such adjustments, the prescription can significantly relieve the symptoms of wound erosion, exudation and itching caused by damp-toxin accumulation, and gradually dry and flatten the wound.
[0049] Example 6
[0050] For patients with severe heat-toxin and local necrosis, it is manifested as local tissue necrosis of the wound surface, redness, swelling and heat at the edge, accompanied by fetid secretions, and the pathogenesis is "heat-toxin stasis, necrotic flesh not yet shed".
[0051] The ethnic medicine composition for treating chronic diseases described in this example, the raw material weight ratio of the ethnic medicine composition is: 20 parts of Astragalus membranaceus, 10 parts of Angelica sinensis, 15 parts of Lonicera japonica, 10 parts of Glycyrrhiza uralensis, 10 parts of Fructus mume, 5 parts of Schisandra chinensis, 7 parts of Smilax glabra, 5 parts of Dictamnus dasycarpus, 5 parts of Ganoderma lucidum, 8 parts of Saposhnikovia divaricata, 10 parts of Lithospermum erythrorhizon, 5 parts of Rhizoma zedoariae, 5 parts of Paeonia lactiflora, 5 parts of Bupleurum chinense, 1 part of Rhodiola rosea, 1 part of Carthamus tinctorius, 1 part of Phyllanthus emblica.
[0052] The key to the treatment of such patients is to clear heat and detoxify, remove necrosis and promote granulation. On the basis of the original formula, the dosage of Astragalus membranaceus should be adjusted from 15 parts to 20 parts. Astragalus membranaceus has a strong effect of supplementing qi to support detoxification, expelling pus and removing necrosis to promote granulation, tonifying qi aspect to generate muscles. The dosage of Angelica sinensis remains unchanged. Angelica sinensis nourishes blood and promotes blood circulation, nourishing blood aspect while also promoting blood circulation, so that Astragalus membranaceus can tonify without stagnation. The dosage of Lonicera japonica is adjusted from 10 parts to 15 parts. Lonicera japonica has a significant effect of clearing heat and detoxifying, and can reduce local infection reaction; enabling Astragalus membranaceus and Angelica sinensis to tonify qi and blood without generating heat. The dosage of Glycyrrhiza uralensis is increased from 5 parts to 10 parts, and the dosage of Paeonia lactiflora is increased from 1 part to 5 parts. The combination of Glycyrrhiza uralensis and Paeonia lactiflora, with the combination of sweet and bitter flavors similar to ginseng, can tonify qi and blood both, and has a stronger effect of removing necrosis and promoting granulation. The dosage of Saposhnikovia divaricata is adjusted to 8 parts, and its effect of expelling wind and dredging collaterals helps the external discharge of heat toxin; the dosage of Prunus mume is adjusted from 5 parts to 10 parts. Prunus mume has the function of removing dead muscles and evil flesh. At the same time, the dosage of Lithospermum erythrorhizon is adjusted to 10 parts. Lithospermum erythrorhizon is cold in nature and mainly treats blood heat and toxin excess, and is an important drug for treating intense heat toxin. The adjusted formula emphasizes both clearing heat and detoxifying and removing necrosis and promoting granulation, and can quickly improve the pathological state of intense heat toxin and non-shedding necrotic tissue, creating good conditions for wound repair.
[0053] The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiments do not describe all details in detail, nor limit the invention to the specific embodiments described. Obviously, many modifications and variations can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principle and practical application of the present invention, so that those skilled in the art can well understand and utilize the present invention. The present invention is only limited by the claims and their full scope and equivalents.
Claims
1. A detoxifying and antipruritic folk medicine composition, characterized in that: The invention comprises 10-20 parts of astragalus, 9-18 parts of angelica, 9-18 parts of honeysuckle, 1-10 parts of liquorice, 1-10 parts of ebony, 1-10 parts of schisandra, 5-15 parts of smilax, 1-10 parts of divaricate cortex, 1-10 parts of ganoderma lucidum, 1-10 parts of siler, 1-10 parts of lithospermum, 1-10 parts of curcuma, 1-5 parts of white peony root, 1-10 parts of bupleurum, 0.5-1.5 parts of rhodiola, 0.5-1.5 parts of safflower, and 0.5-1.5 parts of emblica.
2. The method for preparing a detoxifying and antipruritic folk medicine composition according to claim 1, characterized in that: The following steps are involved: 1) boiling the ethnic medicine components in water to obtain a decoction, and concentrating the decoction; 2) Centrifuging, sterilizing and packaging the obtained concentrated solution to obtain a pharmaceutical composition.
3. The preparation method according to claim 2, characterized in that: Add 6-8 times the amount of water and soak for 35-60 minutes.
4. The preparation method according to claim 2, characterized in that: Decoction for 1-2 hours and filter through gauze.
5. The preparation method according to claim 2, characterized in that: Decoction again, add 4-6 times the amount of water, and decoct again for 25-45 minutes.
6. The preparation method according to claim 2, characterized in that: Concentrate to 1000-2000 ml.
7. The preparation method according to claim 2, characterized in that: The centrifugal speed is 500g / 10min, 2000g / 20min, 3000g / 30min, 5000g / 30min.
8. Use of the detoxifying and antipruritic folk medicine composition according to claim 1 or the detoxifying and antipruritic folk medicine composition prepared by the preparation method according to any one of claims 2 to 7 in the preparation of detoxifying and antipruritic drugs.
9. A drug, characterized in that The invention comprises the detoxifying and antipruritic ethnic medicine composition according to claim 1 or the medicine composition and dressing prepared by the preparation method according to any one of claims 2 to 7.