Herbicide composition containing Epyrifenacil

Abstract

The invention belongs to the technical field of pesticides, and particularly relates to a herbicide composition containing Epyrifenacil. An active component of the herbicide composition is formed by compounding a first herbicidal active component and a second herbicidal active component, wherein the weeding composition comprises a first weeding active ingredient and a second weeding active ingredient, the first weeding active ingredient is Epyrifenacil, and the second weeding active ingredient is selected from any one of cinmethylin, aclonifen and pyroxasulfone. According to the invention, Epyrifenacil is compounded with the existing herbicide cinmethylin, aclonifen or pyroxasulfone, and indoor tests find that the compounded composition shows a combined synergistic effect on prevention and removal of weeds, so that the prevention and removal effect on farmland weeds can be improved, and the pesticide application amount, pesticide residue and environmental pressure can be reduced. And secondly, compared with a single herbicide, the herbicide composition disclosed by the invention can reduce the generation and development of herbicide resistance of weeds, prolong the service life of the herbicide and contribute to scientifically and effectively treating resistant weeds.

Description

Technical Field

[0001] The present invention belongs to the technical field of pesticides, and particularly relates to a herbicide composition containing Epyrifenacil. Background Art

[0002] Epyrifenacil is a herbicide of the protoporphyrinogen oxidase (PPO) inhibitor type developed by Sumitomo Chemical Co., Ltd., with CAS No.: 353292-31-6 and molecular formula: C 21 H6ClF4N3O6, and its structure is as follows:

[0003]

[0004] The International Herbicide Resistance Action Committee (HRAC) classifies Epyrifenacil into Group 14, with the N-phenylimide structural type. Epyrifenacil is broad-spectrum and fast-acting, and is mainly used for corn, wheat, rice, sorghum, soybeans, cotton, sugar beets, peanuts, sunflowers, rapeseed, flowers, vegetables, etc., and can be used to control a variety of broad-leaved weeds and gramineous weeds. The prior art has disclosed that 10% Epyrifenacil emulsifiable concentrate can completely control Pharbitis nil and Abutilon theophrasti 16 days after post-emergence spraying at 125 g a.i. / hm 2 or 19 days after soil spraying at 500 g a.i. / hm 2 In addition, the prior art

[0005] Cinmethylin is a benzyl ether herbicide developed by BASF with a unique chemical structure and novel mechanism of action. It is a pre-emergence herbicide with a long-lasting effect. Cinmethylin is a selective inhibitor of acyl carrier protein (ACP) fatty acid thioesterase (FAT). By inhibiting fatty acid biosynthesis and destroying cell membranes, it causes weeds to die. It is mainly absorbed by the buds and roots of seedling weeds and is conducted through the xylem to the growth points of roots and buds, hindering the mitosis of meristematic cells and causing plant death.

[0006] Aclonifen is a diphenyl ether herbicide, and its target of action is solanesyl pyrophosphate synthase (SPS). Inhibition of SPS can cause a sharp drop in the plastid quinone level in weeds, ultimately resulting in the bleaching of weeds. Aclonifen can control broad-leaved weeds and gramineous weeds in sunflower, potato, winter wheat fields, etc., and has the advantages of fast action, flexible application method, and no impact on subsequent crops. When applied before emergence, aclonifen is safe for crops, and after soil tillage, it can be planted 5 weeks after application.

[0007] Pyroxasulfone is an isoxazoline herbicide jointly developed by Nippon Soda Co., Ltd. and Aihara Chemical Co., Ltd. in Japan. It is classified as a K3 herbicide and belongs to a cell division inhibitor. After application, it is absorbed by the young roots and shoots of weeds, inhibits the early growth of seedlings, damages the meristem and coleoptile, and is a serious potential inhibitor in the biosynthesis of very long chain fatty acids (VLCFAs) in plants. Pyroxasulfone mainly acts on pre-emergence soil treatment and can effectively control annual gramineous weeds and annual broad-leaved weeds.

[0008] Farmland weeds compete with crops for light, water, nutrients, etc., seriously affecting the safe growth of crops. Herbicides are the most economical and effective means to control farmland weeds in modern agricultural production. With the unscientific use of herbicides, many problems such as weed resistance have also emerged. With the increasing annual resistance of weeds, the control effect of herbicides will gradually decrease. The large-dose use of herbicides also has problems of excessive pesticide residues and increased environmental pollution. In order to improve the control effect on weeds, scientifically and effectively control resistant weeds, reduce the dosage and control cost, the compounding of different herbicides has become a better solution in current production practice.

[0009] Currently, there are no relevant reports on the compounding of Epyrifenacil with cinmethylin, acifluorfen or pyroxasulfone.

[0010] The information disclosed in this background art section is only intended to increase the understanding of the overall background of the present invention and should not be regarded as an admission or any form of implication that this information constitutes prior art already known to those of ordinary skill in the art. Summary of the Invention

[0011] The purpose of the present invention is to provide a herbicide composition containing Epyrifenacil to solve the many problems such as weed resistance caused by the unscientific use of herbicides. With the increasing annual resistance of weeds, the control effect of herbicides will gradually decrease. The large-dose use of herbicides also has problems of excessive pesticide residues and increased environmental pollution.

[0012] To achieve the above purpose, the present invention provides the following technical solutions:

[0013] A herbicide composition, wherein the active ingredients of the herbicide composition are compounded from a first herbicidal active ingredient and a second herbicidal active ingredient; wherein, the first herbicidal active ingredient is Epyrifenacil, and the second herbicidal active ingredient is selected from any one of cinmethylin, acifluorfen or pyroxasulfone.

[0014] More preferably, the compounding mass ratio of Epyrifenacil to cinmethylin is 1 - 5:15 - 1.

[0015] More preferably, the compounding mass ratio of Epyrifenacil to acifluorfen is 1-15:40-1.

[0016] More preferably, the compounding mass ratio of Epyrifenacil to pyraoxystrobin is 1-20:10-1.

[0017] The present invention also provides a herbicide, and the herbicide comprises the herbicide composition described above.

[0018] More preferably, the mass of the herbicide composition accounts for 0.5-65% of the total mass of the herbicide, and the balance is auxiliary components allowed to be added in pesticide science.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] (1) In the present invention, Epyrifenacil is compounded with the existing herbicides cinmethylin, acifluorfen or pyraoxystrobin. Through indoor tests, it is found that the compounding combinations show a synergistic effect on weed control, can improve the control effect on farmland weeds, help reduce the application amount of pesticides, reduce pesticide residues and environmental pressure. In addition, the utilization rate of existing herbicides can also be improved.

[0021] (2) Compared with single herbicides, the herbicide composition of the present invention can reduce the generation and development of weed resistance, extend the service life of herbicides, help scientifically and effectively control resistant weeds, and provide support for the development of new and highly efficient herbicides. Specific embodiments

[0022] The technical solutions of the present invention will be clearly and completely described below. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative efforts belong to the scope of protection of the present invention.

[0023] Example: Indoor bioactivity test of Epyrifenacil compound

[0024] 1. Test weeds

[0025] Alopecurus japonicus and Malachium aquaticum, and the weed seeds were collected from the fields of Luoshan County, Xinyang City.

[0026] 2. Test agents

[0027] 95% Epyrifenacil, 98% cinmethylin, 98% acifluorfen, 97% pyraoxystrobin. The above agents are all from the laboratory of the Institute of Plant Protection, Henan Academy of Agricultural Sciences.

[0028] The test agents were first dissolved in dimethyl sulfoxide and then diluted with a 0.1% Tween-80 aqueous solution to form a single-agent stock solution. Multiple groups of ratios were set, and each single agent and the mixed agents of each group ratio were further diluted with a 0.1% Tween-80 aqueous solution into 5 mass concentration gradients. The above agents were prepared and used immediately.

[0029] 3. Test method

[0030] The toxicity of each single agent and the mixed agents to the test weeds was determined by the soil spraying method. Field soil was taken, air-dried, passed through a 20-mesh sieve, and filled to 4 / 5 of the pot (diameter 7 cm, height 10 cm). The soil was completely moistened by bottom seepage irrigation. The germinated test weed seeds with white tips were evenly sown on the soil surface, 20 seeds per pot, and covered with 0.5 cm of soil. After 24 h, soil spraying treatment was carried out using the 3WP-2000 type walking bioassay spray tower of the Nanjing Institute of Agricultural Mechanization. Each mass concentration of the liquid medicine was set with 5 replicates, and each pot was 1 replicate. And the treatment with 0.1% Tween-80 aqueous solution was used as the blank control.

[0031] After the treatment, the emergence of weeds and their growth status after emergence were regularly observed visually. The fresh weight of the above-ground parts of the weeds was weighed 21 days after the application of the medicine, and the control effect of the fresh weight was calculated. The ED of each single agent and the mixed agents with different ratios was obtained using DPS software. 50 The co-toxicity coefficient (CTC value) of the mixed agent was calculated using the Sun Yunpei method.

[0032] 5. Calculation method

[0033]

[0034] In the above formula: E - control effect of fresh weight (%); C - fresh weight of the above-ground parts of the control weeds (g); T - fresh weight of the above-ground parts of the treated weeds (g).

[0035]

[0036] In the above formula: ATI - actual toxicity index of the mixed agent; S - ED of the standard agent. 50 , with the unit of g a.i. / hm2; M - ED of the test agent. 50 , with the unit of g a.i. / hm. 2 .

[0037] TTI = TI A ×P A +TI B ×P B

[0038] In the above formula: TTI - theoretical toxicological index of the mixed agent; TI A - toxicity index of agent A; P A--Percentage content of Agent A in the mixture, in percentage (%);TI B --Toxicity index of Agent B;P B --Percentage content of Agent B in the mixture, in percentage (%).

[0039]

[0040] In the above formula: CTC - co-toxicity coefficient; ATI - measured toxicity index of the mixture; TTI - theoretical toxicity index of the mixture.

[0041] 6. Evaluation of agents

[0042] The synergistic effect of mixed agents is evaluated according to the co-toxicity coefficient (CTC), that is, CTC ≤ 80 is antagonistic effect, 80 < CTC < 120 is additive effect, and CTC ≥ 120 is synergistic effect. The results are shown in Table 1-3.

[0043] Table 1 Indoor bioassay of the combination of Epyrifenacil and cinmethylin against Alopecurus japonicus

[0044]

[0045] As can be seen from Table 1, the co-toxicity coefficients of Epyrifenacil and cinmethylin in the mass ratio range of 1-5:15-1 are all greater than 120, that is, the bioactivity of the combination of Epyrifenacil and cinmethylin against Alopecurus japonicus shows a synergistic effect.

[0046] Table 2 Indoor bioassay of the combination of Epyrifenacil and acifluorfen-methyl against Alopecurus japonicus

[0047]

[0048] As can be seen from Table 2, the co-toxicity coefficients of Epyrifenacil and acifluorfen-methyl in the mass ratio range of 1-15:40-1 are all greater than 120, that is, the bioactivity of the combination of Epyrifenacil and acifluorfen-methyl against Alopecurus japonicus shows a synergistic effect.

[0049] Table 3 Indoor bioassay of the combination of Epyrifenacil and pyraflufen-ethyl against Stellaria media

[0050]

[0051] As can be seen from Table 3, the co-toxicity coefficients of Epyrifenacil and pyraflufen-ethyl in the mass ratio range of 1-20:10-1 are all greater than 120, that is, the bioactivity of the combination of Epyrifenacil and pyraflufen-ethyl against Stellaria media shows a synergistic effect.

[0052] In summary, the present invention combines Epyrifenacil with existing herbicides such as cinmethylin, acifluorfen-methyl or pyraoxystrobin. Through indoor tests, it is found that the combined formulations show a synergistic effect in controlling weeds, which can improve the control effect on farmland weeds, help reduce the application amount of pesticides, and reduce pesticide residues and environmental pressure. In addition, the utilization rate of existing herbicides can also be increased.

[0053] The foregoing description of specific exemplary embodiments of the present invention is for purposes of illustration and exemplification. These descriptions are not intended to limit the invention to the precise forms disclosed, and obviously, many modifications and variations are possible in light of the above teachings. The purpose of selecting and describing the exemplary embodiments is to explain the specific principles of the present invention and its practical applications, so that those skilled in the art can implement and utilize various different exemplary embodiments of the present invention, as well as various different selections and modifications. The scope of the present invention is intended to be defined by the claims and their equivalents.

Claims

1. A herbicide composition, characterized in that: The active ingredient of the herbicide composition is compounded by a first herbicidal active ingredient and a second herbicidal active ingredient; wherein the first herbicidal active ingredient is Epyrifenacil, and the second herbicidal active ingredient is selected from any one of cyproconazole, benifloxybutyl or pyraclostrobin.

2. The herbicide composition according to claim 1, characterized in that The composite mass ratio of Epyrifenacil to cyproconazole is 1-5:15-1.

3. The herbicide composition according to claim 1, characterized in that The compounding mass ratio of Epyrifenacil to benitobutyl is 1-15:40-1.

4. The herbicide composition according to claim 1, characterized in that The compounding mass ratio of Epyrifenacil to pyraclostrobin is 1-20:10-1.

5. A herbicide, characterized in that: The herbicide comprises the herbicide composition according to any one of claims 1 to 4.

6. The herbicide according to claim 5, characterized in that The mass of the herbicide composition accounts for 0.5-65% of the total mass of the herbicide, and the remainder is auxiliary components allowed to be added in pesticide science.

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