Cyantraniliprole suspending agent and application thereof
By mixing deltamethrin and calciumamide and adding biological synergists to form calciumamide suspension agent, the existing pesticides have been solved, with poor effect, high residual amount and enhanced drug resistance in preventing and treating calcium aphids, and efficient, safe and environmentally friendly pesticide use effects are achieved.
Patent Information
- Application Number
- CN202311790620.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-25
- Publication Date
- 2025-06-27
AI Technical Summary
When preventing and controlling kale aphids, existing pesticides are difficult to effectively control, and they are large in use and high in residues, which affect crop growth and human health, and are prone to pest resistance. When mixed with other pesticides, they are prone to jelly-like, precipitation, and flocculent blocking of spray heads.
The two agents of deltamethrin and lemoniamide are mixed and bio-stimulant are added to form a lemoniamide suspension agent. By spraying, the permeability and adhesion of pesticides are improved, the crop's disease resistance is enhanced, and the pesticide residues and pest resistance are reduced.
It significantly improves the prevention and control effect of kale aphids, reduces pesticide residues and pest resistance, improves pesticide utilization and compatibility with other pesticides, and has the effect of treating multiple drugs with one drug, quick effect and sustaining effect.
Smart Images
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Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of pesticides, and particularly relates to a cyantraniliprole suspension concentrate and its application. Background Art
[0002] Deltamethrin is one of the pyrethroid insecticides with the highest toxicity. It has contact and stomach poisoning effects. The contact effect is rapid, and the knockdown power is strong. It has no fumigation and systemic effects. At high concentrations, it has a repellent effect on some pests. It has a broad insecticidal spectrum and is effective against a variety of pests such as Lepidoptera, Orthoptera, Thysanoptera, Hemiptera, Diptera, Coleoptera, etc., but has very low or no efficacy against mites, scale insects, and mirids, and will also stimulate the reproduction of mites. When insects and mites occur simultaneously, it needs to be mixed with a special acaricide. Deltamethrin belongs to the medium-toxic category. Skin contact can cause irritation symptoms, such as red papules. In case of acute poisoning, the symptoms are headache, dizziness, nausea, vomiting, loss of appetite, fatigue in mild cases, and muscle fasciculation and convulsions in severe cases. It has an irritating effect on human skin and eye mucosa, and is highly toxic to fish and bees. Insects resistant to DDT show cross-resistance to deltamethrin.
[0003] Cyantraniliprole is a new type of amide systemic insecticide, mainly with stomach poisoning and also having contact toxicity. By activating the ryanodine receptor of the target pests, it releases the calcium stored in the striated and smooth muscle cells, causing the pests' muscle contraction, resulting in damage to muscle movement regulation, paralysis, and ultimately the death of the pests.
[0004] The cabbage aphid Brevicoryne brassicae (Linnaeus), a pest of the Cruciferae family, has 8 - 10 generations per year with overlapping generations. It overwinters as eggs, mainly on late cabbage, followed by kohlrabi, winter radish, and winter Chinese cabbage. In warm regions, it can also reproduce parthenogenetically throughout the year. Cabbage aphids like to suck the plant sap on cruciferous vegetables with smooth leaves and more wax, causing the leaves to curl and deform, the plant to grow poorly, affecting the hearting, and polluting the leaf surface due to a large amount of excreted honeydew and molting, and can also transmit virus diseases, resulting in losses far greater than the direct damage of aphids. Due to the growth characteristics of cabbage and the spraying habits of growers, multiple pesticides are often mixed. With the increase in greenhouse cabbage planting, the occurrence of pests and diseases is becoming more serious, the resistance of pests and diseases is increasing, and the use of chemical pesticides is also increasing. And it is difficult to wash off pesticide residues and bacteria and viruses during consumption. Therefore, how to reduce pesticide residues, reduce virus transmission, and reduce the amount of pesticide use is an urgent problem to be solved, and it can be mixed with other pesticides without problems such as jelly formation, precipitation, and flocculation blocking the nozzle.
[0005] The applicant mixes two agents with completely different action mechanisms and adds a biological synergist, which can increase the systemic absorption and adhesion of the liquid medicine, effectively control cabbage aphids, is also safe and environmentally friendly, can enhance the immunity of crops, not only can control pests, but also can enhance the disease resistance of crops, improve the deposition, adhesion and penetration of pesticides on the leaf surface, improve the utilization rate of pesticides, and
[0006] the compatibility of mixing with other pesticides, and has the effects of treating multiple diseases with one drug, quick-acting and long-lasting. Therefore, the mixture of deltamethrin and cyantraniliprole is worthy of popularization and application in agricultural production. Summary of the Invention
[0007] The object of the present invention is to provide a cyantraniliprole suspension and its application, which can effectively control cabbage aphids, is also safe and environmentally friendly, has a small residue amount and a low dosage, can enhance the immunity of crops, not only can control pests, but also can enhance the disease resistance of crops, improve the deposition, adhesion and penetration of pesticides on the leaf surface, improve the utilization rate of pesticides, improve the compatibility of mixing with other pesticides, and has the effects of treating multiple diseases with one drug, quick-acting and long-lasting.
[0008] The technical solution of the present invention is as follows:
[0009] A cyantraniliprole suspension composition and its application, characterized in that: the suspension composition contains an effective active ingredient, a biological synergist, an auxiliary agent and water; the effective active ingredient is deltamethrin and cyantraniliprole; wherein the weight ratio of deltamethrin to cyantraniliprole is 1:1 to 1:4, preferably, the weight ratio of deltamethrin to cyantraniliprole is 1:3.
[0010] Further, the biological synergist is selected from amino acids or biological enzymes.
[0011] Further, the auxiliary agent is selected from one or more of a dispersant, a wetting agent, an antifreeze, a thickener, an antifoaming agent, a pH regulator, and a preservative.
[0012] Further, based on 1000 parts by weight of the suspension composition, it comprises the following raw material components: 10-200 parts by weight of deltamethrin, 50-400 parts by weight of cyantraniliprole, 10-200 parts by weight of biological synergist, 40-400 parts by weight of auxiliary agent, and the balance is water.
[0013] Further, 30-100 parts by weight of deltamethrin, 100-300 parts by weight of cyantraniliprole, 4-150 parts by weight of biological synergist, 10-70 parts by weight of dispersant, 20-80 parts by weight of wetting agent, 0-60 parts by weight of antifreeze, 2-25 parts by weight of thickener, 0.5-15 parts by weight of antifoaming agent, 0.05-5 parts by weight of pH regulator, 0-20 parts by weight of preservative, and the balance is water.
[0014] Further, 50 parts by weight of deltamethrin, 150 parts by weight of cyantraniliprole, 50 - 100 parts by weight of biological synergist, 30 - 45 parts by weight of dispersant, 30 - 50 parts by weight of wetting agent, 30 - 50 parts by weight of antifreeze, 5 - 10 parts by weight of thickener, 0.5 - 10 parts by weight of defoamer, 0.1 - 3 parts by weight of pH regulator, 3 - 150 parts by weight of preservative, and the balance being water.
[0015] Further, the dispersant is selected from one or more of alkyl naphthalene sulfonates, alkyl naphthalene sulfonate formaldehyde polymers, lignin sulfonates, fatty alcohol polyoxyethylene ether phosphates, polycarboxylates, comb-shaped polycarboxylates, EO-PO block copolymers, and phenethylphenol polyoxyethylene ether phosphates; the wetting agent is selected from one or more of alkyl sulfonates, alkyl naphthalene sulfonates, fatty alcohol polyoxyethylene ethers, alkyl glycosides, trisiloxane polyoxyethylene ethers, polyaryl phenol polyoxyethylene ethers, and castor oil polyoxyethylene ethers; the antifreeze is selected from one or more of ethylene glycol, propylene glycol, glycerol, polyethylene glycol, allantoin, and sorbitol; the thickener is selected from one or more of xanthan gum, polyvinyl alcohol, magnesium aluminum silicate, sodium carboxymethyl cellulose, sodium alginate, and guar gum; the defoamer is a silicone defoamer, a C10-20 saturated fatty acid compound, or a C8-10 fatty alcohol; the pH regulator is selected from one or more of citric acid and glacial acetic acid; the preservative is benzoic acid and its sodium salt, isothiazolinone, sorbic acid and its sodium or potassium salt.
[0016] Further, the total weight of the effective active ingredients in the suspension composition is 60 - 600 g / L, optionally 100 - 400 g / L, and optionally 200 g / L.
[0017] Further, the weight ratio of the effective active ingredient to the biological synergist is 20:20:(1 - 5).
[0018] Further, the application of the cyantraniliprole suspension composition in controlling cabbage aphids. When the suspension composition is used to control cabbage aphids, it is used by spraying at the initial peak stage of the occurrence of cabbage aphids, and the dosage of the active ingredient is 10 - 50 g / ha, preferably 30 - 36 g / ha.
[0019] Compared with the prior art, the composition of the present invention has the following beneficial effects: (1) Compared with single agents, the composition has obvious synergistic effects on cabbage aphids and significantly improves the control effect; (2) It improves the penetration and adhesion of the liquid medicine and increases the utilization rate of pesticides; (3) It is safe for crops and not easy to cause phytotoxicity; (4) It delays the pest resistance; (5) It improves the compatibility with other pesticides when mixed, and has the functions of treating multiple diseases with one drug, quick effect and long-lasting effect. Detailed implementation methods
[0020] The present invention will be further described below in conjunction with embodiments, but the present invention is not limited thereto.
[0021] Application Example 1
[0022] The following suspension composition is based on 1000 parts by weight and contains the following components:
[0023]
[0024] Application Example 2:
[0025] Indoor combined toxicity determination experiment of deltamethrin, cyantraniliprole and their mixtures against cabbage aphids
[0026] 1 Test purpose
[0027] To determine the toxicity of deltamethrin, cyantraniliprole and their different mixed combinations against cabbage aphids indoors, evaluate the synergistic effect, clarify their compatibility, and provide a scientific basis for the research and development of the mixture of deltamethrin and cyantraniliprole.
[0028] 2 Experimental conditions
[0029] 2.1 Test target
[0030] Cabbage aphids (Brevioryne brassicae)), and the test targets used are the adults that have naturally occurred and reproduced for multiple generations on the cabbages planted in the test base without any pesticide application.
[0031] 2. Culture conditions
[0032] The culture conditions for the test targets and the targets after the test are temperature (25±1)°C, relative humidity 60% - 80%, and light cycle L∶D=(16∶8)h.
[0033] 3 Test design
[0034] 3.1 Test agents
[0035] 98% deltamethrin technical; 94% cyantraniliprole technical.
[0036] 3.2 Agent preparation
[0037] Weigh 0.0106 g of 94% cyantraniliprole technical material, dissolve it in 1 mL of DMF, add 0.2 mL of Tween 80 emulsifier, stir well, add water to make up to 100 mL to prepare a stock solution of 100 mg / L. Then take 20 mL of the stock solution and add it to 80 mL of water containing 0.1% Tween 80 emulsifier to prepare a test solution of 20 mg / L. Then dilute it with water containing 0.1% Tween 80 emulsifier according to a 2-fold ratio to 10, 5, 2.5, 1.25, and 0.625 mg / L, and conduct tests at a total of 6 concentrations.
[0038] Weigh 0.0102 g of 98% deltamethrin technical material, dissolve it in 0.5 mL of DMF, add 0.2 mL of Tween 80 emulsifier, stir well, add water to make up to 100 mL to prepare a stock solution of 100 mg / L. Then take 4 mL of the stock solution and add it to 96 mL of water containing 0.1% Tween 80 emulsifier to prepare a test solution of 4 mg / L. Then dilute it with water containing 0.1% Tween 80 emulsifier according to a 2-fold ratio to 2, 1, 0.5, 0.25, and 0.125 mg / L, and conduct tests at a total of 6 concentrations.
[0039] According to the ratios of cyantraniliprole to deltamethrin of 4:1, 3:1, 2:1, 1:1, and 1:2, respectively measure 6.4, 6, 5.33, 2, and 1.33 mL of the cyantraniliprole stock solution, and then correspondingly measure 1.6, 2, 2.67, 2, and 2.67 mL of the deltamethrin stock solution. Mix the two, make up to 100 mL with water containing the emulsifier to prepare test solutions of 8, 8, 8, 4, and 4 mg / L respectively. Then dilute them with water containing 0.1% Tween 80 emulsifier according to a 2-fold ratio to 6 concentrations each for testing.
[0040] Add 99 mL of water containing 0.1% Tween 80 emulsifier to a beaker containing 1 mL of DMF as a blank control.
[0041] 4 Test method
[0042] Refer to the indoor bioassay test guidelines for pesticides NY / T 1154.6 - 2006 and adopt the method of dipping insects. Use 30 healthy and consistent nymphs of cabbage aphids for each repeated treatment, with 4 replicates for each treatment, and set up a treatment without the pesticide (including the used solvent and emulsifier) as a blank control. After the treatment, place them in the observation room for cultivation.
[0043] 5 Data investigation and statistical analysis
[0044] 5.1 Investigation time and method
[0045] Check the death situation of the test insects after 48 h and record it. The judgment standard for the death of the test insects is that if there is no response when gently touching the test insects with a pointed writing brush, it is counted as dead.
[0046] 5.2 Data statistical analysis
[0047] Referring to the indoor bioassay test guidelines for pesticides NY / T1154.7 - 2006, the co - toxicity coefficient (CTC) of each mixture combination was calculated using the co - toxicity coefficient method of Sun & Johnson (1960). CTC ≤ 80 indicates antagonistic effect, 80 < CTC < 120 indicates additive effect, and CTC ≥ 120 indicates synergistic effect. The formula for calculating the co - toxicity coefficient is as follows:
[0048]
[0049] The theoretical toxicity index (TTI) of the mixture = toxicity index of pesticide A × percentage of pesticide A in the mixture (%) + toxicity index of pesticide B × percentage of pesticide B in the mixture (%)
[0050]
[0051] 6 Experimental results
[0052] Table 1 Toxicity determination results of the mixture of cyantraniliprole and deltamethrin against cabbage aphids
[0053]
[0054] The toxicity determination results of the mixture of cyantraniliprole and deltamethrin at the ratios of 4:1, 3:1, 2:1, 1:1, and 1:2 against cabbage aphids are shown in Table 1. From Table 1 of the test results, it can be seen that the toxicities (LC 50 ) of the two pesticides in different ratios against the nymphs of cabbage aphids are 1.19, 1.03, 0.99, 0.83, and 0.75 mg / L respectively, and the co - toxicity coefficients CTC are 134.72, 142.26, 129.46, 123.47, and 113.83 respectively. Among them, the synergistic effect is the most significant when the weight ratio of cyantraniliprole to deltamethrin is 3∶1.
[0055] Application Example 3: Field efficacy test of controlling cabbage aphids
[0056] 1 Test purpose
[0057] To verify the control effect of the 200 g / L cypermethrin·cyantraniliprole suspension concentrate developed by the applicant against cabbage aphids and its safety to cabbages, clarify the field application dosage and application techniques, and provide a scientific basis for pesticide registration.
[0058] 2 Test basis
[0059] "Good Laboratory Practice for Pesticide Registration Tests", "NY / T 1464.27-2010, Guidelines for Field Efficacy Trials of Pesticides - Insecticides against Aphids on Cruciferous Vegetables in the People's Republic of China Agricultural Industry Standard", "NWP-SOP-I-012, Operating Procedures for Field Trials of Aphids on Cruciferous Vegetables".
[0060] 3 Experimental Sites
[0061] This test is arranged in Shaanxi Province and Shandong Province.
[0062] 4 Selection of Test Objects, Crops and Varieties
[0063] Test Object: Cabbage Aphids
[0064] Test Crop: Cabbage, with good growth.
[0065] 5 Experimental Design and Arrangement
[0066] 5.1 Dosage and Numbering of Pesticides
[0067] Table 2 Experimental Design of Test Pesticides
[0068]
[0069] 5.2 Application Time, Investigation Time and Frequency
[0070] Apply the pesticide once at the initial peak of cabbage aphid occurrence. Investigate the initial pest population before pesticide application, and investigate the pest population at 1d, 3d, 7d, and 10d after pesticide application, for a total of 5 times.
[0071] 5.3 Application Volume
[0072] Spray 50 liters of liquid medicine per mu, and 750 liters of liquid medicine per hectare.
[0073] 5.4 Method for Calculating Efficacy
[0074]
[0075]
[0076] 6 Experimental Results
[0077] Table 3 Field Control Efficacy of 200 g / L Deltamethrin · Cyantraniliprole Suspension Concentrate against Cabbage Aphids
[0078]
[0079] Table 4 Field Control Efficacy of 200 g / L Deltamethrin · Cyantraniliprole Suspension Concentrate against Cabbage Aphids
[0080]
[0081] The experimental results show that: the test substance, 200 g / L deltamethrin·cyantraniliprole suspension concentrate, is used to control cabbage aphids. It is sprayed once during the peak period of cabbage aphid occurrence. When the application rate of the active ingredient is 30 - 36 g / ha, it has both quick-acting and long-lasting effects. The control efficacy reaches over 90% after 7 days and 10 days of application, and the control effects are significantly better than those of the control single agents in the control experiment. According to the variance analysis, there are extremely significant differences between 200 g / L deltamethrin·cyantraniliprole suspension concentrate and the control single agents. During the entire experimental period, it is safe for crops, safe for applicators, and also has a certain control effect on other pests.
Claims
1. A cyantraniliprole suspension composition and its application, characterized in that: The suspension composition contains an effective active ingredient, a biological synergist, an adjuvant, and water; the effective active ingredient is deltamethrin and cyantraniliprole; the weight ratio of deltamethrin to cyantraniliprole is 1:1 to 1:4; Based on 1000 parts by weight, the suspension composition comprises the following raw materials: 10 - 200 parts by weight of deltamethrin, 50 - 400 parts by weight of cyantraniliprole, 10 - 200 parts by weight of biological synergist, 40 - 400 parts by weight of adjuvant, and the balance is water.
2. The suspension composition according to claim 1, wherein: The weight ratio of deltamethrin to cyantraniliprole is 1:
3.
3. The suspension composition according to claim 1, characterized in that: The biological synergist is selected from amino acids or biological enzymes.
4. The suspension composition according to any one of claims 1 to 3, characterized in that: The adjuvant is selected from one or more of a dispersant, a wetting agent, an antifreeze, a thickener, an antifoaming agent, a pH regulator, and a preservative.
5. The suspension composition according to claim 4, characterized in that: Based on 1000 parts by weight, the suspension composition consists of the following components in the following contents: 30 - 100 parts by weight of deltamethrin, 100 - 300 parts by weight of cyantraniliprole, 4 - 150 parts by weight of biological synergist, 10 - 70 parts by weight of dispersant, 20 - 80 parts by weight of wetting agent, 0 - 60 parts by weight of antifreeze, 2 - 25 parts by weight of thickener, 0.5 - 15 parts by weight of antifoaming agent, 0.05 - 5 parts by weight of pH regulator, 0 - 20 parts by weight of preservative, and the balance is water.
6. The suspension composition according to claim 5, wherein: Based on 1000 parts by weight, the suspension composition consists of the following components in the following contents: 50 parts by weight of deltamethrin, 150 parts by weight of cyantraniliprole, 50 - 100 parts by weight of biological synergist, 30 - 45 parts by weight of dispersant, 30 - 50 parts by weight of wetting agent, 30 - 50 parts by weight of antifreeze, 5 - 10 parts by weight of thickener, 0.5 - 10 parts by weight of antifoaming agent, 0.1 - 3 parts by weight of pH regulator, 3 - 150 parts by weight of preservative, and the balance is water.
7. The suspension composition according to claim 6, wherein: The dispersant is selected from one or more of alkylnaphthalene sulfonates, alkylnaphthalene sulfonate formaldehyde polymers, lignosulfonates, fatty alcohol polyoxyethylene ether phosphates, polycarboxylates, comb-shaped polycarboxylates, EO-PO block copolymers, and phenethylphenol polyoxyethylene ether phosphates; The wetting agent is selected from one or more of alkyl sulfonates, alkylnaphthalene sulfonates, fatty alcohol polyoxyethylene ethers, alkyl glycosides, trisiloxane polyoxyethylene ethers, polyaryl phenol polyoxyethylene ethers, and castor oil polyoxyethylene ethers; The antifreeze is selected from one or more of ethylene glycol, propylene glycol, glycerol, polyethylene glycol, allantoin, and sorbitol; The preservative is benzoic acid and its sodium salt, isothiazolinone, sorbic acid and its sodium or potassium salt; The antifoaming agent is a silicone antifoaming agent, C10-20 saturated fatty acid compounds, C8-10 fatty alcohols; The thickener is selected from one or more of xanthan gum, polyvinyl alcohol, magnesium aluminum silicate, sodium carboxymethyl cellulose, sodium alginate, and guar gum.
8. The suspension composition according to claim 1, characterized in that: The total weight of the effective active ingredients in the suspension composition is 60 - 600 g / L, optionally 100 - 400 g / L, and optionally 200 g / L.
9. Use of the cyantraniliprole suspension composition according to any one of claims 1 to 8 in controlling cabbage aphids.