Natural diet for activating islet cells and promoting blood glucose metabolism

Abstract

The invention belongs to the technical field of health-care products, and particularly relates to a natural diet for activating islet cells and promoting blood glucose metabolism, which comprises the following food raw materials in parts by weight: 15-20 parts of mulberry leaves, 8-12 parts of radix polygonati officinalis, 10-15 parts of Chinese yam, 8-12 parts of kudzuvine roots, 6-10 parts of bitter gourds, 5-8 parts of radishes, 5-10 parts of mulberries, 8-12 parts of guavas, 5-8 parts of rhizoma polygonati and 5-10 parts of moringa oleifera leaves. The natural diet has the beneficial effects that the blood sugar level of a diabetic patient can be remarkably reduced, the components synergistically inhibit absorption of disaccharide by small intestines, insulin secretion is promoted, fasting blood glucose and postprandial blood glucose are effectively reduced, experimental data shows that the blood sugar of the diabetic patient taking the natural diet is remarkably reduced, the effect is superior to that of an existing product, and the natural diet is worthy of popularization and application. Various components in the natural diet have the effect of activating islet cells, for example, mucus protein in the Chinese yam can protect the islet cells and enhance the functions of the islet cells, and the islet functions of diabetic patients can be remarkably improved and dependence on drugs and insulin can be reduced after the natural diet is taken for a long time.

Description

Technical Field

[0001] The present invention belongs to the technical field of health care products, and particularly relates to a natural diet that activates pancreatic islet cells and promotes blood glucose metabolism. Background Art

[0002] Diabetes is a chronic disease with a high global incidence, characterized by hyperglycemia. Long-term hyperglycemia can lead to various complications, such as cardiovascular diseases, kidney diseases, retinopathy, etc. According to statistics from the World Health Organization (WHO), the number of global diabetes patients has increased significantly in the past few decades, especially in developing countries, bringing great pain to patients and imposing a heavy burden on the social medical system. Summary of the Invention

[0004] To solve the problems raised in the above background art, the present invention provides a natural diet that activates pancreatic islet cells and promotes blood glucose metabolism, which has the characteristics of convenient preparation, large-scale production and promotion, and significant blood glucose lowering effect.

[0005] To achieve the above object, the present invention provides the following technical solution: A natural diet that activates pancreatic islet cells and promotes blood glucose metabolism, comprising the following food raw materials in parts by weight: 15 - 20 parts of mulberry leaves, 8 - 12 parts of polygonatum odoratum, 10 - 15 parts of Chinese yam, 8 - 12 parts of kudzu root, 6 - 10 parts of balsam pear, 5 - 8 parts of radish, 5 - 10 parts of mulberry, 8 - 12 parts of guava, 5 - 8 parts of polygonatum sibiricum, 5 - 10 parts of moringa leaves.

[0006] Preferably, it further comprises the following auxiliary materials in parts by weight: 30 - 50 parts of flour, 2 - 5 parts of yeast, 1 - 3 parts of edible salt, 5 - 10 parts of vegetable oil.

[0007] Preferably, the mulberry leaves are dried mulberry leaves, and its preparation method comprises the following steps: Wash the fresh mulberry leaves and place them in a ventilated place to dry; Put the dried mulberry leaves into an oven and dry them at 40 - 50 °C until the moisture content is lower than 5%; Crush the dried mulberry leaves into a powder of 80 - 100 mesh.

[0008] Preferably, the balsam pear is dried balsam pear without seeds, and its preparation method is: Wash the balsam pear and cut it into thin slices, remove the seeds; Put the balsam pear slices into an oven and dry them at 50 - 60 °C until the moisture content is lower than 8%; Crush the dried balsam pear slices into a powder of 60 - 80 mesh.

[0009] Preferably, the radish is dried radish shreds, and its preparation method comprises the following steps: Wash the radish and cut it into fine shreds; Place the radish shreds in the sun and expose them until completely dry, turning them over every 2 hours during the period; Crush the dried radish shreds into a powder of 60 - 80 mesh.

[0010] Preferably, the preparation method of the natural diet comprises the following steps:

[0011] (1) Treat each food raw material into powder by weight to obtain each raw material powder;

[0012] (2) Mix the raw material powders evenly to obtain a mixed powder;

[0013] (3) Add the auxiliary materials described in claim 2 to the mixed powder, mix evenly, and make into dough;

[0014] (4) Put the dough into a mold to make a pastry shape, and steam it in a steamer for 15 - 20 minutes;

[0015] (5) Take out the steamed pastry, cool it and then package it to obtain the finished product.

[0016] Preferably, the steaming temperature in step (4) is 100 °C, and the cooling temperature in step (5) is room temperature.

[0017] Preferably, the natural diet can also be made into dosage forms such as granules, extracts, oral liquids, etc.

[0018] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0019] 1. Significant hypoglycemic effect: The natural diet of the present invention can significantly reduce the blood glucose level of diabetic patients. Each component synergistically inhibits the absorption of disaccharides in the small intestine and promotes insulin secretion, effectively reducing fasting blood glucose and postprandial blood glucose. Experimental data show that the blood glucose of diabetic patients taking this natural diet decreases significantly, and the effect is better than that of existing products.

[0020] 2. Repair pancreatic islet cells: Multiple components in the natural diet of the present invention have the effect of activating pancreatic islet cells. For example, the polysaccharide in Polygonatum odoratum can improve the sensitivity of insulin and promote the repair of pancreatic islet cells; the mucoprotein in Dioscorea opposita can protect pancreatic islet cells and enhance their function. Long-term taking can significantly improve the pancreatic islet function of diabetic patients and reduce the dependence on drugs and insulin.

[0021] 3. Safe and without side effects: The natural diet of the present invention uses natural components, which have been strictly screened and processed to ensure the safety of the product. Experimental data show that no obvious toxic reaction is found in mice and rats taking this natural diet, and there is no side effect on the human body after long-term taking. Compared with traditional drug treatment, it has higher safety and is suitable for long-term taking by diabetic patients.

[0022] 4. Convenient and easy to use: The preparation process of the natural diet of the present invention is simple, suitable for large-scale production and promotion. Dosage forms such as tablets, granules or oral liquids prepared are convenient for patients to take and easy to adhere to for a long time. In addition, other dosage forms can be prepared according to needs, such as tea bags for substituting tea, further improving the convenience of the product. Detailed implementation manners

[0023] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0024] Embodiment 1

[0025] The present invention provides the following technical solution: A natural diet for activating pancreatic islet cells to promote blood glucose metabolism, comprising the following food raw materials in parts by weight: 15 parts of mulberry leaves, 12 parts of polygonatum odoratum, 10 parts of Chinese yam, 10 parts of kudzu root, 8 parts of balsam pear, 5 parts of radish, 8 parts of mulberry, 10 parts of guava, 5 parts of polygonatum sibiricum, 8 parts of moringa leaves, 40 parts of flour, 3 parts of yeast, 1 part of edible salt, and 8 parts of vegetable oil.

[0026] The production steps are as follows:

[0027] Raw material treatment: Dry and crush mulberry leaves, polygonatum odoratum, Chinese yam, kudzu root, balsam pear, radish, mulberry, guava, polygonatum sibiricum, and moringa leaves respectively, and pass through an 80-mesh sieve.

[0028] Mixing: Mix the crushed raw materials with flour, yeast, edible salt, and vegetable oil in proportion.

[0029] Shaping: Make into dough, shape with a mold, steam for 15 - 20 minutes, and cool and package.

[0030] Experimental data: In the acute oral toxicity experiment of mice, no obvious poisoning manifestations were found, nor any deaths. In the blood glucose lowering efficacy experiment, compared with the control group, the natural diet of the present invention can significantly reduce the blood glucose value.

[0031] Embodiment 2

[0032] The present invention provides the following technical solution: A natural diet for activating pancreatic islet cells to promote blood glucose metabolism, comprising the following food raw materials in parts by weight: 20 parts of mulberry leaves, 8 parts of polygonatum odoratum, 15 parts of Chinese yam, 8 parts of kudzu root, 10 parts of balsam pear, 8 parts of radish, 5 parts of mulberry, 12 parts of guava, 8 parts of polygonatum sibiricum, 5 parts of moringa leaves, 30 parts of flour, 5 parts of yeast, 3 parts of edible salt, and 10 parts of vegetable oil.

[0033] The production steps are as follows:

[0034] Raw material processing - Dry and pulverize mulberry leaves, polygonatum odoratum, Chinese yam, kudzu root, balsam pear, radish, mulberry, guava, polygonatum sibiricum, and moringa leaves respectively, and sieve through a 100-mesh sieve.

[0035] Mixing - Mix the pulverized raw materials with flour, yeast, edible salt, and vegetable oil in proportion.

[0036] Shaping - Make into dough, shape with a mold, steam for 15 - 20 minutes, and cool and package.

[0037] Experimental data: In the acute oral toxicity experiment on mice, no obvious poisoning manifestations were found, nor any deaths. In the blood sugar lowering efficacy experiment, compared with the control group, the natural diet of the present invention can significantly reduce the blood sugar value.

[0038] Example 3

[0039] The present invention provides the following technical solution: A natural diet for activating pancreatic islet cells and promoting blood sugar metabolism, comprising the following food raw materials in parts by weight: 18 parts of mulberry leaves, 10 parts of polygonatum odoratum, 13 parts of Chinese yam, 12 parts of kudzu root, 7 parts of balsam pear, 6 parts of radish, 7 parts of mulberry, 9 parts of guava, 6 parts of polygonatum sibiricum, 7 parts of moringa leaves, 35 parts of flour, 4 parts of yeast, 2 parts of edible salt, and 6 parts of vegetable oil.

[0040] The production steps are as follows:

[0041] Raw material processing: Dry and pulverize mulberry leaves, polygonatum odoratum, Chinese yam, kudzu root, balsam pear, radish, mulberry, guava, polygonatum sibiricum, and moringa leaves respectively, and sieve through a 90-mesh sieve.

[0042] Mixing: Mix the pulverized raw materials with flour, yeast, edible salt, and vegetable oil in proportion.

[0043] Shaping: Make into dough, shape with a mold, steam for 15 - 20 minutes, and cool and package.

[0044] Experimental data: No obvious poisoning manifestations and deaths were found in the acute oral toxicity experiment on mice. The blood sugar lowering efficacy experiment shows that, compared with the control group, this natural diet significantly reduces the blood sugar value. Detect the pancreatic islet function of diabetic model mice, and the results show that long-term consumption of this natural diet can effectively repair damaged pancreatic islet cells, improve insulin secretion ability, and improve pancreatic islet function.

[0045] Example 4

[0046] The present invention provides the following technical solution: A natural diet for activating pancreatic islet cells and promoting blood sugar metabolism, comprising the following food raw materials in parts by weight: 16 parts of mulberry leaves, 14 parts of polygonatum odoratum, 12 parts of Chinese yam, 15 parts of kudzu root, 9 parts of balsam pear, 7 parts of radish, 9 parts of mulberry, 11 parts of guava, 7 parts of polygonatum sibiricum, 9 parts of moringa leaves, 45 parts of flour, 2 parts of yeast, 1.5 parts of edible salt, and 9 parts of vegetable oil.

[0047] The production steps are as follows:

[0048] Raw material treatment: Dry and pulverize mulberry leaves, polygonatum odoratum, Chinese yam, kudzu root, balsam pear, radish, mulberry, guava, polygonatum sibiricum, and moringa leaves respectively, and pass through an 80-mesh sieve.

[0049] Mixing: Mix the pulverized raw materials with flour, yeast, edible salt, and vegetable oil in proportion.

[0050] Shaping: Make the dough, shape it with a mold, steam for 15 - 20 minutes, and cool and package.

[0051] Experimental data: No obvious poisoning manifestations and deaths were found in the acute oral toxicity experiment of mice. The hypoglycemic efficacy experiment showed that compared with the control group, this natural diet significantly reduced the blood glucose value. The lipid metabolism of diabetic model mice was detected, and the results showed that this natural diet could effectively reduce the contents of total cholesterol, triglyceride, and low-density lipoprotein cholesterol in the serum, while increasing the content of high-density lipoprotein cholesterol, improving lipid metabolism disorders, and preventing the occurrence of diabetic complications.

[0052] Example 5

[0053] The present invention provides the following technical solution: A natural diet for activating pancreatic islet cells and promoting blood glucose metabolism, comprising the following food raw materials in parts by weight: 20 parts of mulberry leaves, 12 parts of polygonatum odoratum, 15 parts of Chinese yam, 10 parts of kudzu root, 10 parts of balsam pear, 8 parts of radish, 10 parts of mulberry, 12 parts of guava, 8 parts of polygonatum sibiricum, 10 parts of moringa leaves, 50 parts of flour, 3 parts of yeast, 2 parts of edible salt, and 10 parts of vegetable oil.

[0054] The production steps are as follows:

[0055] Raw material treatment: Dry and pulverize mulberry leaves, polygonatum odoratum, Chinese yam, kudzu root, balsam pear, radish, mulberry, guava, polygonatum sibiricum, and moringa leaves respectively, and pass through a 100-mesh sieve.

[0056] Mixing: Mix the pulverized raw materials with flour, yeast, edible salt, and vegetable oil in proportion.

[0057] Shaping: Make the dough, shape it with a mold, steam for 15 - 20 minutes, and cool and package.

[0058] Experimental data: No obvious poisoning manifestations and deaths were found in the acute oral toxicity experiment of mice. The hypoglycemic efficacy experiment showed that compared with the control group, this natural diet significantly reduced the blood glucose value. The antioxidant capacity of diabetic model mice was detected, and the results showed that this natural diet could significantly increase the activities of superoxide dismutase and catalase in the serum, reduce the content of malondialdehyde, enhance the antioxidant capacity of the body, and reduce oxidative stress damage.

[0059] Clinical experiment

[0060] Experimental subjects: A total of 100 cases, 50 males and 50 females, aged 40 - 70 years old.

[0061] Dosage and administration: Take before meals, 3 times a day, 4 - 6 g each time, and 4 weeks is a treatment course.

[0062] Experimental results: After treatment, both the fasting blood glucose and postprandial blood glucose of the patients were significantly decreased. At the same time, the glycated hemoglobin level of the patients also decreased significantly, indicating that the natural diet of the present invention has a good effect on long - term blood glucose control. In addition, the blood lipid indexes of the patients such as total cholesterol, triglyceride and low - density lipoprotein cholesterol all decreased, and the high - density lipoprotein cholesterol increased, indicating that the natural diet of the present invention also has the effect of regulating blood lipids.

[0063] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A natural diet for activating pancreatic islet cells and promoting blood sugar metabolism, characterized in that: The invention comprises the following food raw materials in parts by weight: 15-20 parts of mulberry leaves, 8-12 parts of polygonatum odoratum, 10-15 parts of yam, 8-12 parts of kudzu root, 6-10 parts of bitter melon, 5-8 parts of radish, 5-10 parts of mulberry, 8-12 parts of guava, 5-8 parts of polygonatum odoratum and 5-10 parts of moringa leaves.

2. The natural diet for activating pancreatic islet cells and promoting blood sugar metabolism according to claim 1, characterized in that: The invention also includes the following auxiliary materials in parts by weight: 30-50 parts of flour, 2-5 parts of yeast, 1-3 parts of edible salt, and 5-10 parts of vegetable oil.

3. The natural diet for activating pancreatic islet cells and promoting blood sugar metabolism according to claim 1, characterized in that: The mulberry leaves are dried mulberry leaves, and the preparation method thereof comprises the following steps: washing fresh mulberry leaves and placing them in a ventilated place to dry; placing the dried mulberry leaves in an oven and drying them at 40-50° C. until the moisture content is less than 5%; and crushing the dried mulberry leaves into 80-100 mesh powder.

4. The natural diet for activating pancreatic islet cells and promoting blood sugar metabolism according to claim 1, characterized in that: The bitter melon is a dried bitter melon after removing the seeds. The preparation method thereof is as follows: washing the bitter melon, cutting it into thin slices, and removing the seeds; putting the bitter melon slices into an oven, and drying them at 50-60° C. until the moisture content is less than 8%; and crushing the dried bitter melon slices into 60-80 mesh powder.

5. The natural diet for activating pancreatic islet cells and promoting blood sugar metabolism according to claim 1, characterized in that: The radish is sun-dried shredded radish, and the preparation method thereof comprises the following steps: washing the radish and cutting it into thin shreds; exposing the shredded radish to the sun until it is completely dried, and turning it over every 2 hours; and crushing the sun-dried shredded radish into powder of 60-80 meshes.

6. The natural diet for activating pancreatic islet cells and promoting blood sugar metabolism according to claim 1, characterized in that: The method for preparing the natural diet comprises the following steps: (1) processing each food raw material into powder according to weight to obtain each raw material powder; (2) mixing the raw material powders uniformly to obtain mixed powder; (3) adding the auxiliary material according to claim 2 to the mixed flour, mixing evenly, and making a dough; (4) putting the dough into a mold, shaping it into a pastry shape, and steaming it in a steamer for 15-20 minutes; (5) taking out the steamed cake, cooling it and packaging it to obtain the finished product.

7. The method for preparing a natural diet for activating pancreatic islet cells and promoting blood sugar metabolism according to claim 6, characterized in that: The steaming temperature described in step (4) is 100° C., and the cooling temperature described in step (5) is room temperature.

8. The natural diet for activating pancreatic islet cells and promoting blood sugar metabolism according to claim 1, characterized in that: The natural diet can be prepared into granules, granules and oral liquid dosage forms.