Improved honeysuckle crude extraction process

Abstract

The invention provides an improved honeysuckle crude extraction process which comprises the following steps: step 1, preparing a certain amount of honeysuckle medicinal material, putting honeysuckle into a cleaning container, cleaning the honeysuckle, and primarily filtering impurities in the honeysuckle medicinal material by adopting a filter screen; step 2, putting the cleaned honeysuckle into a drying machine, setting the operation time of the drying machine to be 2-5 hours, drying the honeysuckle, then putting the dried honeysuckle into a crushing device, and crushing the honeysuckle through the crushing device to finally obtain honeysuckle powder, the extraction method is simple, process conditions are easy to control, the obtained medicinal extract is stable in quality, effective components of honeysuckle can be effectively reserved, guarantee is provided for subsequent reprocessing of the honeysuckle extract, meanwhile, the process provided by the invention is simple and convenient to operate, no other materials need to be added in the whole process, and the method is suitable for industrial production. And the manual labor is effectively saved.

Description

Technical Field

[0001] The present invention relates to the field of honeysuckle, and specifically to an improved process for the rough extraction of honeysuckle. Background Art

[0002] The plant honeysuckle, also known as Lonicera japonica, is a perennial semi-evergreen twining woody vine of the Caprifoliaceae family. Since the newly opened honeysuckle flowers are white and then turn yellow, it is named honeysuckle. Honeysuckle has been praised as a good medicine for clearing heat and detoxifying since ancient times. It is sweet, cold in nature and fragrant. Its sweet and cold nature can clear heat without harming the stomach, and its fragrance can penetrate and dispel pathogenic factors. Honeysuckle can not only disperse wind-heat, but also effectively clear blood toxins, and is effective in treating various febrile diseases, such as fever, rash, macula, heat-toxic sores and boils, sore throat and other symptoms. Similarly, the extract of honeysuckle is also the main raw material for medicines, health products and cosmetics;

[0003] In the prior art, the preparation method for the extraction of honeysuckle is complex and cumbersome, with low yield, high cost, and difficult to master, which is not suitable for industrial production. Therefore, there is an urgent need for an improved technology to solve this problem existing in the prior art. Summary of the Invention

[0004] (1) Technical Problem to be Solved

[0005] In view of the deficiencies of the prior art, the present invention provides an improved process for the rough extraction of honeysuckle, which solves the problems of complex and cumbersome extraction method, low yield, high cost and difficult to master in the prior art.

[0006] (2) Technical Solution

[0007] To achieve the above objectives, the present invention is realized through the following technical solutions: An improved process for the rough extraction of honeysuckle, comprising the following steps:

[0008] Step 1: Prepare a quantitative amount of honeysuckle medicinal materials, put the honeysuckle into a cleaning container for cleaning, and initially filter the impurities in the honeysuckle medicinal materials using a filter screen;

[0009] Step 2: Put the cleaned honeysuckle into the interior of a dryer, and at the same time set the operating time of the dryer to 2 - 5 h to dry the honeysuckle. Then put the dried honeysuckle into a pulverizing device, and the pulverizing device can pulverize the honeysuckle to finally obtain honeysuckle powder;

[0010] Step 3: Put the honeysuckle powder into a steamer, add water to the steamer, introduce steam into the interior of the steamer, and set the time of the steamer to 2 - 6 h to obtain a primary extract;

[0011] Step 4: Separate the primary extract obtained in Step 3 at a separation speed of 200 - 500 revolutions per hour for a centrifugation time of 20 - 30 minutes. Take the supernatant, perform membrane separation, wash and filter with water, and combine the filtrates to obtain a crude extract.

[0012] Step 5: Let the crude extract obtained in Step 4 stand, take the supernatant, concentrate it under reduced pressure until the water content is less than 5%, and dry it to obtain the finished honeysuckle extract.

[0013] Preferably, the cleaning equipment in Step 1 is an ultrasonic cleaner, and the cleaning time is 15 minutes to 30 minutes.

[0014] Preferably, the drying temperature in Step 2 is 30 - 50 °C.

[0015] Preferably, the pressure in the steam pot in Step 3 is 0.1 - 0.4 Mpa.

[0016] Preferably, the drying time in Step 5 is 0.8 - 3 hours, and the drying temperature is 35 - 45 °C.

[0017] (III) Beneficial effects

[0018] The present invention provides an improved crude extraction process for honeysuckle, having the following beneficial effects:

[0019] 1. The extraction method adopted in the present invention is simple, the process conditions are easy to control, the quality of the obtained medicinal extract is stable, and the active ingredients of honeysuckle can be effectively retained, providing a guarantee for the subsequent reprocessing of honeysuckle extract. At the same time, the process provided by the present invention is simple, easy to operate, and no other materials need to be added throughout the process, effectively saving labor.

[0020] 2. The present invention can extract honeysuckle by ultrasonic cleaning, which can significantly improve the extraction efficiency and shorten the extraction time. At the same time, the vibration of ultrasonic waves can also destroy the cell structure in honeysuckle, enabling the active ingredients to be fully released and improving the purity of the extract. Specific embodiments

[0021] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0022] Example 1:

[0023] The embodiment of the present invention provides an improved crude extraction process for honeysuckle, including the following steps:

[0024] Step 1: Prepare a quantitative amount of honeysuckle herbs. Put the honeysuckle into a cleaning container for cleaning, and use a filter screen to initially filter the impurities in the honeysuckle herbs.

[0025] Step 2: Put the cleaned honeysuckle into the dryer. At the same time, set the running time of the dryer to 2 hours to dry the honeysuckle. Then put the dried honeysuckle into the pulverizing equipment to pulverize the honeysuckle, and finally obtain honeysuckle powder.

[0026] Step 3: Put the honeysuckle powder into a steamer, and add water to the steamer. Steam is introduced into the steamer, and the time of the steamer is set to 2 hours to obtain a primary extract.

[0027] Step 4: Separate the primary extract obtained in Step 3. The separation speed is 200 revolutions per hour, and the centrifugation time is 20n. Take the supernatant, perform membrane separation, and wash and filter with water. Combine the filtrates to obtain a crude extract.

[0028] Step 5: Let the crude extract obtained in Step 4 stand, take the supernatant, concentrate it under reduced pressure until the water content is below 5%, and dry it to obtain the finished honeysuckle extract.

[0029] The cleaning equipment in Step 1 is an ultrasonic cleaning machine, and the cleaning time is 15 minutes.

[0030] The drying temperature in Step 2 is 30.

[0031] The pressure in the steamer in Step 3 is 0.1 Mpa

[0032] The drying time in Step 5 is 0.8 hours, and the drying temperature is 35 °C.

[0033] Example 2:

[0034] The embodiment of the present invention provides an improved process for crude extraction of honeysuckle, including the following steps:

[0035] Step 1: Prepare a quantitative amount of honeysuckle herbs. Put the honeysuckle into a cleaning container for cleaning, and use a filter screen to initially filter the impurities in the honeysuckle herbs.

[0036] Step 2: Put the cleaned honeysuckle into the dryer. At the same time, set the running time of the dryer to 3.5 hours to dry the honeysuckle. Then put the dried honeysuckle into the pulverizing equipment to pulverize the honeysuckle, and finally obtain honeysuckle powder.

[0037] Step 3: Put the honeysuckle powder into a steamer, add water to the steamer, introduce steam into the steamer, and set the time of the steamer at 4 h to obtain a primary extract.

[0038] Step 4: Separate the primary extract obtained in Step 3 at a separation speed of 350 revolutions per hour for 25 min. Take the supernatant, perform membrane separation, wash and filter with water, and combine the filtrates to obtain a crude extract.

[0039] Step 5: Let the crude extract obtained in Step 4 stand, take the supernatant, concentrate it under reduced pressure until the water content is below 5%, and dry it to obtain the finished honeysuckle extract.

[0040] The cleaning equipment in Step 1 is an ultrasonic cleaner, and the cleaning time is 20 min.

[0041] The drying temperature in Step 2 is 40 °C.

[0042] The pressure in the steamer in Step 3 is 0.3 Mpa

[0043] The drying time in Step 5 is 1.7 h, and the drying temperature is 40 °C

[0044] Example 3:

[0045] The embodiment of the present invention provides an improved process for the crude extraction of honeysuckle, including the following steps:

[0046] Step 1: Prepare a quantitative amount of honeysuckle medicinal materials, put the honeysuckle into a cleaning container for cleaning, and initially filter the impurities in the honeysuckle medicinal materials using a filter screen.

[0047] Step 2: Put the cleaned honeysuckle into the dryer, and at the same time set the running time of the dryer at h to dry the honeysuckle. Then put the dried honeysuckle into the pulverizing equipment, and the honeysuckle can be pulverized by the pulverizing equipment to finally obtain honeysuckle powder.

[0048] Step 3: Put the honeysuckle powder into a steamer, add water to the steamer, introduce steam into the steamer, and set the time of the steamer at 6 h to obtain a primary extract.

[0049] Step 4: Separate the primary extract obtained in Step 3 at a separation speed of 500 revolutions per hour for 30 min. Take the supernatant, perform membrane separation, wash and filter with water, and combine the filtrates to obtain a crude extract.

[0050] Step 5: Let the crude extract obtained in Step 4 stand, take the supernatant, concentrate it under reduced pressure until the water content is below 5%, and dry it to obtain the finished honeysuckle extract.

[0051] The cleaning equipment in Step 1 is an ultrasonic cleaner, and the cleaning time is 130 min.

[0052] The drying temperature in Step 2 is 50 °C.

[0053] The pressure in the steamer in Step 3 is 0.4 Mpa

[0054] The drying time in Step 5 is 3 h, and the drying temperature is 45 °C.

[0055] Example 4:

[0056] The honeysuckle extracts obtained in Examples 1 to 3 were detected. By selecting an absorption wavelength of 327 nm, the content of chlorogenic acid in the honeysuckle extract in each test sample was measured in a UV spectrophotometer, and then the content of chlorogenic acid in each group of test samples was calculated. Furthermore, the extraction rate of chlorogenic acid was calculated, and the data were recorded to obtain Table 1:

[0057]

[0058]

[0059] As shown in the above table, under the crude extraction process of this patent, the content of chlorogenic acid in honeysuckle is within the optimal range. It can be seen that the process method in this patent can improve the extraction effect of honeysuckle, the quality of the obtained medicinal extract is stable, the active ingredients of honeysuckle can be effectively retained, and it provides a guarantee for the subsequent reprocessing of honeysuckle extract.

[0060] Although the embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An improved process for crude extraction of honeysuckle, characterized in that: The following steps are involved: Step 1: prepare a certain amount of honeysuckle medicinal materials, put the honeysuckle into a cleaning container to clean it, and use a filter to filter out impurities in the honeysuckle medicinal materials for the first time; Step 2: putting the washed honeysuckle into a dryer, and setting the running time of the dryer to 2 to 5 hours, so as to dry the honeysuckle, and then putting the dried honeysuckle into a crushing device, so as to crush the honeysuckle by the crushing device, and finally obtaining honeysuckle powder; Step 3: Put the honeysuckle powder into a steamer, add water into the steamer, pass steam into the steamer, and set the steaming time to 2 to 6 hours to obtain the primary extract; Step 4: Separate the primary extract obtained in step 3 at a separation speed of 200 to 500 rpm for 20 to 30 min, take the supernatant, perform membrane separation, and perform filter washing with water, combine the filtrate, and obtain a crude extract; Step 5: The crude extract obtained in step 4 is allowed to stand, the supernatant is taken, and it is concentrated under reduced pressure to a moisture content of less than 5%, and dried to obtain a finished honeysuckle extract.

2. An improved honeysuckle crude extraction process according to claim 1, characterized in that: The cleaning equipment in step 1 is an ultrasonic cleaning machine, and the cleaning time is 15 minutes to 30 minutes.

3. An improved honeysuckle crude extraction process according to claim 2, characterized in that: The drying temperature in step 2 is 30-50°C.

4. An improved honeysuckle crude extraction process according to claim 1, characterized in that: In step 3, the pressure in the steamer is 0.1-0.4Mpa.

5. An improved honeysuckle crude extraction process according to claim 1, characterized in that: The drying time in step 5 is 0.8 to 3 hours, and the drying temperature is 35 to 45°C.

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