High-speed reagent split charging device

Abstract

The invention discloses a high-speed reagent split charging device. The device comprises a base, a shell, a sampling assembly, a sample dripping assembly and a sample loading assembly, the shell is arranged at the rear end of the top surface of the base; the sampling assembly is arranged on the front end surface of the shell; the sample dripping assembly comprises a first transmission part, a second transmission part and a sample dripping part; the first transmission part is arranged in the shell and extends in the vertical direction. The second transmission part is at least partially arranged on the first transmission part and extends in the front-back direction. The sample dripping piece is movably arranged on the second transmission piece; the first transmission part can drive the second transmission part to move in the vertical direction. The second transmission piece can drive the sample dripping piece to move in the front-back direction; the sample dripping piece is connected with the sampling assembly through the infusion tube; the sample loading assembly comprises a supporting table and a loading disc; the supporting table is movably arranged at the bottom of the shell in the left-right direction. The carrying disc is arranged on the supporting table; and a sub-packaging piece is arranged on the carrying disc. Through the arrangement, the reagent split charging device is higher in positioning accuracy and flexibility and higher in distribution efficiency.

Description

Technical Field

[0001] The present invention relates to the technical field of reagent production, and particularly to a high-speed reagent dispensing device. Background Art

[0002] In the fields of biological experiments, medical tests, chemical analysis, etc., reagent dispensing devices are widely used in sample processing and reagent dispensing.

[0003] Currently, traditional reagent dispensing devices usually adopt a single-axis or double-axis motion structure to achieve the positioning of the sample dropping component and reagent dispensing. However, such devices have certain limitations during operation. For example, the movement path of the sample dropping component is relatively fixed, unable to flexibly adapt to different specifications of sample containers, and limited by the transmission structure, the overall operation efficiency is relatively low. In addition, due to relying only on a single or double-axis motion driving method, the positioning accuracy of the sample dropping component may be affected, resulting in a large error during the reagent dispensing process, affecting the accuracy and reliability of the experiment.

[0004] On the other hand, the sample loading component of existing reagent dispensing devices usually uses a fixed track or a one-way moving mechanism to convey the sample tray. This method is prone to problems such as slow running speed and low sample loading efficiency when processing a large number of samples, and it is difficult to meet the requirements of modern laboratories for high-speed and high-precision reagent dispensing. Summary of the Invention

[0005] In order to solve the deficiencies of the prior art, the purpose of the present invention is to provide a high-speed reagent dispensing device. The reagent dispensing device has higher positioning accuracy, stronger flexibility, and higher dispensing efficiency.

[0006] Based on the above purpose, the present invention adopts the following technical solutions: A high-speed reagent dispensing device, comprising: a base, a housing, a sampling assembly, a sample dropping assembly, and a sample loading assembly; the housing is installed at the rear end of the top surface of the base; at least part of the sampling assembly is installed on the front surface of the housing and is communicated with an external liquid storage tank through a plurality of infusion tubes; the sample dropping assembly includes a first transmission member, a second transmission member, and a sample dropping member; at least part of the first transmission member is arranged inside the housing and extends in the up and down direction; at least part of the second transmission member is arranged on the first transmission member and extends in the front and back direction; the sample dropping member is movably arranged on the second transmission member; the first transmission member can drive the second transmission member to move in the up and down direction; the second transmission member can drive the sample dropping member to move in the front and back direction; the sample dropping member is connected with the sampling assembly through an infusion tube; the sample loading assembly includes a support platform and a sample loading tray; the support platform is movably arranged at the bottom of the housing in the left and right direction; at least part of the sample loading tray is arranged on the support platform; a dispensing member is arranged on the sample loading tray; when the reagent dispensing device works, the sampling assembly extracts the reagent from the liquid storage tank and transmits it to the sample dropping member; the first transmission member and the second transmission member cooperate to align the sample dropping member with the sample loading assembly; the sample loading assembly moves in the left and right direction, and the dispensing member collects the reagent.

[0007] Further, a third transmission member extending in the left and right direction is arranged inside the housing, the rear end of the support platform is movably arranged on the third transmission member, and the third transmission member can drive the support platform to move in the left and right direction.

[0008] Further, a collection part for collecting the leaked liquid is arranged at the position corresponding to the lower part of the first transmission member on the base, and a liquid discharge port is arranged at the front end of the collection part.

[0009] Further, support parts for supporting the support platform are respectively arranged on the left and right sides at the front end of the collection part, and rollers are arranged at the tops of the support parts.

[0010] Further, a support plate is arranged inside the housing; the first transmission member includes a first lead screw, a first driving member, and a first guide rail; the first driving member is arranged on the support plate, and the first driving member is in transmission connection with the first lead screw; the second transmission member is movably arranged on the first guide rail and at least partially sleeved on the first lead screw; the first driving member can drive the second transmission member to move in the up and down direction through the first lead screw.

[0011] Further, the second transmission member includes a second lead screw, a second driving member, and a second guide rail; the second guide rail extends in the front and back direction, the rear end is movably arranged on the first guide rail and at least partially sleeved on the first lead screw; the second driving member is at least partially arranged on the second guide rail; the second lead screw is arranged above the second guide rail and is connected with the second driving member.

[0012] Further, the sample dropping member includes a transmission part and a clamping part; the transmission part and the clamping part are fixedly connected or integrally formed; the transmission part is movably arranged on the second guide rail and sleeved on the second lead screw; the clamping part is used for fixing the infusion tube led out from the sampling assembly.

[0013] Further, the sampling assembly includes a housing, a cover, a third driving member, and a pump body; the rear end of the housing is installed on the support plate; at least a part of the third driving member is disposed at the rear end of the inner cavity of the housing; at least a part of the pump body is disposed in the housing and extends substantially in the front-rear direction and is connected to the third driving member; the cover is installed on the top of the housing and is substantially in an "I" shape, thereby forming an inlet pipe orifice and an outlet pipe orifice on the top of the housing; the infusion tube enters the housing from the inlet pipe orifice, bypasses the bottom of the pump body to the outlet pipe orifice, and the infusion tube is closely attached to the pump body.

[0014] Further, the sampling assembly further includes a first liquid separation card connector and a second liquid separation card connector for separating the infusion tube; the first liquid separation card connector is detachably disposed at the inlet pipe orifice; the second liquid separation card connector is detachably disposed at the outlet pipe orifice; the droplet sample member includes a third liquid separation card connector corresponding to the second liquid separation card connector, and the third liquid separation card connector is detachably disposed on the clamping portion.

[0015] Further, the reagent dispensing device further includes a control module and a display module; the control module is electrically connected or communicatively connected to the sampling assembly, the droplet sample assembly, and the sample loading assembly respectively; at least a part of the display module is installed on the front end face of the housing and is connected to the control module.

[0016] The present invention provides a high-speed reagent dispensing device. Through the cooperative action of the first transmission member and the second transmission member, precise positioning of the droplet sample assembly is achieved, enabling it to align with the sample loading assembly for reagent dispensing. Meanwhile, the mobility of the sample loading assembly allows the reagent to be collected at different positions, improving the efficiency and accuracy of reagent dispensing. The structure of the present invention is compact and can meet the requirements of high-speed and high-precision reagent dispensing, and is applicable to fields such as biomedicine and chemical analysis. Description of the Drawings

[0017] Figure 1 is the overall structural schematic diagram of the high-speed reagent dispensing device provided by the present invention; Figure 2 is the structural schematic diagram of the high-speed reagent dispensing device without the housing according to the present invention; Figure 3 is the structural schematic diagram of the droplet sample assembly provided by the present invention; Figure 4 is the assembly schematic diagram of the third liquid separation card connector provided by the present invention; Figure 5 is the structural schematic diagram of the sampling assembly provided by the present invention. Detailed Embodiments

[0018] Combined with the embodiments of the present invention, the technical solutions in the embodiments will be clearly and completely described. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

[0019] At the same time, in order to clearly illustrate the technical solution of the present application, the upper side, lower side, left side, right side, front side and rear side as shown in Figure 1 are also defined.

[0020] As shown in Figure 1 and Figure 3 the present application provides a high-speed reagent dispensing device, which includes: a base 1, a housing 2, a sampling assembly 3, a sample dropping assembly 4 and a sample loading assembly 5.

[0021] Specifically, the housing 2 is installed at the rear end of the top surface of the base 1. At least part of the sampling assembly 3 is installed on the front end surface of the housing 2 and is connected to an external liquid storage tank through an infusion tube for extracting reagents from the liquid storage tank.

[0022] The sample dropping assembly 4 includes a first transmission member 41, a second transmission member 42 and a sample dropping member 43. Among them, at least part of the first transmission member 41 is arranged inside the housing 2 and extends in the up and down direction. At least part of the second transmission member 42 is arranged on the first transmission member 41 and extends in the front and rear direction. The sample dropping member 43 is movably arranged on the second transmission member 42. The first transmission member 41 can drive the second transmission member 42 to move in the up and down direction, and the second transmission member 42 can drive the sample dropping member 43 to move in the front and rear direction. The sample dropping member 43 is connected to the sampling assembly 3 through an infusion tube.

[0023] The sample loading assembly 5 includes a support platform 51 and a sample loading tray. At least part of the sample loading tray 52 is arranged on the support platform 51. The support platform 51 is movably arranged at the bottom of the housing 2 in the left and right direction; at least part of the sample loading tray 52 is arranged on the support platform 51. A dispensing member is provided on the sample loading tray 52. Among them, the dispensing member can be a reagent dispensing dish, a reagent cup or other containers.

[0024] When the reagent dispensing device is working, the sampling assembly 3 extracts reagents from the liquid storage tank and transmits them to the sample dropping member 43; the first transmission member 41 and the second transmission member 42 cooperate to align the sample dropping member 43 with the sample loading assembly 5; the sample loading assembly 5 moves in the left and right direction, and the dispensing member collects the reagents.

[0025] With the above settings, the device can achieve automated and high-speed reagent dispensing. Compared with traditional manual operations, it improves work efficiency and dispensing accuracy, and reduces human errors. In addition, through precise transmission mechanisms and multi-axis motion control, the stability and uniformity of reagent dispensing are ensured, while reducing reagent waste. The automatic movement function of the sample loading assembly 5 enhances the overall processing capacity of the equipment and meets the preparation requirements for a large number of samples.

[0026] As Figure 1 shown, a third transmission member 21 extending in the left-right direction is provided inside the housing 2. The rear end of the support table 51 is movably arranged on the third transmission member 21, and the third transmission member 21 can drive the support table 51 to move in the left-right direction. Among them, the third transmission member 21 can be a combination of a servo motor and a lead screw. With the above settings, the dispensing device improves the batch processing capacity of reagents and is suitable for large-scale reagent dispensing.

[0027] Furthermore, a collection part 11 for collecting leaked liquid is provided at the position corresponding to the lower part of the first transmission member 41 on the base 1, avoiding reagent dripping and contaminating the workbench, and keeping the experimental environment clean. A liquid discharge port 12 is provided at the front end of the collection part 11 to discharge excess reagent, reduce liquid accumulation, and improve the convenience of equipment maintenance.

[0028] Support parts 13 for supporting the support table 51 are respectively provided on the left and right sides at the front end of the collection part 11, improving the stability of the support table 51 and reducing shaking. Rollers 14 are provided at the top of the support parts 13 to reduce friction, make the movement of the sample loading assembly 5 smoother, and improve the service life of the equipment.

[0029] As Figure 2 and Figure 3 shown, a support plate 22 is provided inside the housing 2. The first transmission member 41 includes a first lead screw 411, a first driving member 412, and a first guide rail 413. The first driving member 412 is arranged on the support plate 22, and the first driving member 412 is in transmission connection with the first lead screw 411. The second transmission member 42 is movably arranged on the first guide rail 413 and at least partially sleeved on the first lead screw 411. The first driving member 412 can drive the second transmission member 42 to move in the up-down direction through the first lead screw 411. With the above settings, the up-down movement of the sample dropping assembly 4 is more accurate; at the same time, the overall transmission stability is improved through the first guide rail 413, ensuring the reliability of the device during long-term use.

[0030] As Figure 3As shown in the figure, the second transmission member 42 includes a second lead screw 421, a second drive member 422, and a second guide rail 423. The second guide rail 423 extends in the front-rear direction, and its rear end is movably arranged on the first guide rail 413 and at least partially sleeved on the first lead screw 411. The second drive member 422 is at least partially arranged on the second guide rail 423. The second lead screw 421 is arranged above the second guide rail 423 and is connected to the second drive member 422. Through the above arrangement, the front-rear movement of the sample dropping assembly 4 is more precise; at the same time, the movement of the sample dropping assembly 4 is made more stable, improving the stability of reagent dispensing.

[0031] Furthermore, the sample dropping member 43 includes a transmission portion 431 and a clamping portion 432. The transmission portion 431 and the clamping portion 432 are fixedly connected or integrally formed. The transmission portion 431 is movably arranged on the second guide rail 423 and sleeved on the second lead screw 421 to improve mechanical strength and reduce the risk of component loosening; at the same time, the accuracy of the front-rear direction positioning of the sample dropping member 43 can be improved. The clamping portion 432 is used for clamping the infusion tube led out from the sampling assembly 3.

[0032] As Figure 2 shown in the figure, the sampling assembly 3 includes a housing 31, a cover 32, a third drive member 33, and a pump body 34. The rear end of the housing 31 is at least partially arranged on the support plate 22. The third drive member 33 is at least partially arranged at the rear end of the inner cavity of the housing 31. The pump body 34 is at least partially arranged in the housing 31 and extends basically in the front-rear direction and is connected to the third drive member 33. The cover 32 is arranged on the top of the housing 31 and is basically in an "I" shape, thereby forming an inlet pipe orifice and an outlet pipe orifice on the top of the housing 31. The infusion tube enters the housing 31 from the inlet pipe orifice, winds around the bottom of the pump body 34 to the outlet pipe orifice, and the infusion tube is in close fit with the pump body 34. Specifically, the pump body 34 is a four-axis pump. By means of squeezing the infusion by the shaft body, the liquid flow is more stable, the pulsation effect is reduced, and the uniformity of reagent dispensing is improved. At the same time, precise flow regulation can be achieved to ensure that the volume of each dispensing is the same, improving the accuracy of reagent dispensing. In addition, since the four-axis pump adopts a continuous extrusion method, the wear of mechanical friction components is reduced, and it is more durable than traditional pumps, reducing the maintenance cost.

[0033] As Figures 3 to 5As shown, the sampling assembly 3 further includes a first liquid separation quick connector 35 and a second liquid separation quick connector 36 for separating the infusion tube; the first liquid separation quick connector 35 is detachably arranged at the inlet pipe; the second liquid separation quick connector 36 is detachably arranged at the outlet pipe. The sample dropping part 43 includes a third liquid separation quick connector 433 corresponding to the second liquid separation quick connector 36, and the third liquid separation quick connector 433 is detachably arranged on the clamping part 432. Specifically, the first liquid separation quick connector 35 is inserted into the inlet pipe, the second liquid separation quick connector 36 is inserted into the outlet pipe, and the third liquid separation quick connector 433 is inserted into the clamping part 432 to improve the flexibility of disassembly, assembly and replacement of the liquid separation quick connector. Through the above settings, the sampling assembly 3 and the sample dropping assembly 4 can flexibly adjust the model of the liquid separation quick connector according to the reagent dispensing requirements, improving the applicability of the reagent dispensing device.

[0034] More specifically, the sample dropping assembly 4 further includes a fourth liquid separation quick connector 434, and the fourth liquid separation quick connector 434 is clamped on the left side wall of the clamping part 432 for adding small-volume liquid, avoiding frequent replacement of the pipeline and improving the applicability of the reagent dispensing device. Among them, the fourth liquid separation quick connector 434 can be set to 3 channels, and other liquid separation quick connectors can be set to 8 channels to improve the liquid separation efficiency. It should be understood that since the liquid separation quick connector is detachable and replaceable, the number of channels can be configured according to actual needs.

[0035] The reagent dispensing device further includes a control module, and the control module is electrically connected or communicatively connected to the sampling assembly 3, the sample dropping assembly 4 and the sample loading assembly 5 respectively to achieve automated operation, improving the accuracy and repeatability of reagent dispensing. At the same time, the control module is linked with other components, which can improve the intelligence level of the device and minimize manual intervention as much as possible.

[0036] As Figure 1 shown, the reagent dispensing device further includes a display module 6, and at least part of the display module 6 is arranged on the front end face of the housing 2 and is connected to the control module. By using the display module 6 to provide real-time status feedback, it is convenient for users to monitor the operation of the device. At the same time, the displayed parameters can be adjusted, which can improve the convenience of device operation and the ability of personalized settings.

[0037] The above is the description of the embodiments of the present invention. Through the above description of the disclosed embodiments, those skilled in the art can implement or use the present invention. Various modifications to these embodiments will be obvious to those skilled in the art. The general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to these embodiments shown herein, but will conform to the widest scope consistent with the principles and novel points disclosed herein.

Claims

1. A high-speed reagent packaging device, characterized in that: include: Base (1); A shell (2), the shell (2) being arranged at the rear end of the top surface of the base (1); A sampling assembly (3), wherein the sampling assembly (3) is at least partially mounted on the front end surface of the housing (2) and is connected to an external liquid storage tank via a plurality of liquid infusion tubes; A sample dropping component (4), the sample dropping component (4) comprising a first transmission member (41), a second transmission member (42) and a sample dropping member (43); the first transmission member (41) is at least partially disposed in the housing (2) and extends in the up-down direction; the second transmission member (42) is at least partially disposed on the first transmission member (41) and extends in the front-back direction; the sample dropping member (43) is movably disposed on the second transmission member (42); the first transmission member (41) can drive the second transmission member (42) to move in the up-down direction; the second transmission member (42) can drive the sample dropping member (43) to move in the front-back direction; the sample dropping member (43) is connected to the sampling component (3) via an infusion tube; A sample loading assembly (5), the sample loading assembly (5) comprising a support platform (51) and a loading plate (52); the support platform (51) is movably arranged at the bottom of the housing (2) in a left-right direction; the loading plate (52) is at least partially arranged on the support platform (51); and a subassembly component is arranged on the loading plate (52); When the reagent dispensing device is in operation, the sampling component (3) extracts reagent from the liquid storage tank and transmits it to the sample dropping component (43); the first transmission component (41) and the second transmission component (42) cooperate to align the sample dropping component (43) with the sample loading component (5); the sample loading component (5) moves in the left-right direction, and the dispensing component collects the reagent.

2. The high-speed reagent dispensing device according to claim 1, characterized in that: A third transmission member (21) extending in the left-right direction is provided in the housing (2); a rear end of the support platform (51) is movably arranged on the third transmission member (21); and the third transmission member (21) can drive the support platform (51) to move in the left-right direction.

3. The high-speed reagent dispensing device as claimed in claim 2, characterized in that: The base (1) is provided with a collecting portion (11) for collecting leaked liquid at a position corresponding to the lower portion of the first transmission member (41), and a liquid discharge port (12) is provided at the front end of the collecting portion (11).

4. The high-speed reagent dispensing device as claimed in claim 3, characterized in that: Support parts (13) for supporting the support platform (51) are respectively provided on the left and right sides of the front end of the collecting part (11), and a roller (14) is provided on the top of the support part (13).

5. The high-speed reagent dispensing device according to claim 1, characterized in that: A support plate (22) is provided in the housing (2); the first transmission member (41) comprises a first screw rod (411), a first driving member (412) and a first guide rail (413); the first driving member (412) is mounted on the support plate (22), and the first driving member (412) is in transmission connection with the first screw rod (411); the second transmission member (42) is movably arranged on the first guide rail (413), and at least partially sleeved on the first screw rod (411); the first driving member (412) can drive the second transmission member (42) to move in an up-and-down direction via the first screw rod (411).

6. The high-speed reagent dispensing device as claimed in claim 5, characterized in that: The second transmission member (42) comprises a second screw rod (421), a second driving member (422) and a second guide rail (423); the second guide rail (423) extends in the front-rear direction, and the rear end is movably arranged on the first guide rail (413), and at least partially sleeved on the first screw rod (411); the second driving member (422) is at least partially installed on the second guide rail (423); the second screw rod (421) is arranged above the second guide rail (423) and is connected to the second driving member (422).

7. The high-speed reagent dispensing device according to claim 6, characterized in that: The sample dropping member (43) comprises a transmission part (431) and a clamping part (432); the transmission part (431) and the clamping part (432) are fixedly connected or integrally formed; the transmission part (431) is movably arranged on the second guide rail (423) and sleeved on the second screw rod (421); the clamping part (432) is used to fix the infusion tube led out from the sampling assembly (3).

8. The high-speed reagent dispensing device as claimed in claim 7, characterized in that: The sampling assembly (3) comprises a housing (31), a cover (32), a third driving member (33) and a pump body (34); the rear end of the housing (31) is mounted on the support plate (22); the third driving member (33) is at least partially disposed at the rear end of the inner cavity of the housing (31); the pump body (34) is at least partially disposed in the housing (31), substantially extending in the front-to-back direction, and connected to the third driving member (33); the cover (32) is mounted on the top of the housing (31) and is substantially in an "I" shape, thereby forming an inlet and an outlet at the top of the housing (31); an infusion tube enters the housing (31) from the inlet, passes through the bottom of the pump body (34) to the outlet, and the infusion tube is tightly fitted to the pump body (34).

9. The high-speed reagent dispensing device as claimed in claim 8, characterized in that: The sampling assembly (3) further comprises a first liquid separation card connector (35) and a second liquid separation card connector (36) for separating the infusion tube; the first liquid separation card connector (35) is detachably arranged at the tube inlet; the second liquid separation card connector (36) is detachably arranged at the tube outlet; the sample dropping member (43) comprises a third liquid separation card connector (433) corresponding to the second liquid separation card connector (36); the third liquid separation card connector (433) is detachably arranged on the clamping portion (432).

10. The high-speed reagent dispensing device according to claim 1, characterized in that: The reagent dispensing device further comprises a control module and a display module (6); the control module is electrically connected or communicatively connected to the sampling component (3), the sample dropping component (4) and the sample loading component (5) respectively; the display module (6) is at least partially mounted on the front end surface of the housing (2) and is connected to the control module.

Images