Reagent bottle adapter and sample introduction assembly
By designing a reagent bottle adapter that is adapted to different inlet heads, the problem of the reagent bottle adapter connecting with multiple inlet heads is solved, and the stability and cost reduction of the injection process are achieved.
Patent Information
- Application Number
- CN202311871878.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-29
- Publication Date
- 2025-07-01
AI Technical Summary
The existing reagent bottle adapters are difficult to adapt to the injection heads of different sample detection equipment, resulting in unstable injection process and increased cost of use.
A reagent bottle adapter is designed, including a coaxially connected first and second sockets, the groove inner diameter of the first socket is axially changed to accommodate different injection heads, the second socket is docked with the reagent bottle, and the injection needle extends into the groove of the second socket through the through hole to form a sealing connection.
It improves the universal use of reagent bottle adapter, ensures the stability of the injection process and reduces the cost of using the sample detection equipment.
Smart Images
Figure CN120227907A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the field of detection technology, and in particular to a reagent bottle adapter and a sample injection assembly. Background Art
[0002] Before using medical testing equipment for testing, samples, quality control solutions and other reagents required for testing need to be introduced into the sample testing equipment for testing. Since many reagents are easily deteriorated or contaminated after contact with the atmosphere, they are usually stored in sealed reagent bottles such as ampoules. When testing is required, the reagent bottles are opened and the reagents are injected into the sample testing equipment using the injection needle on the injection head of the sample testing equipment.
[0003] However, since it is not stable to directly connect the reagent bottle with the sample detection equipment, the common sample detection equipment is generally connected to one end of the matching adapter, and then the other end of the adapter is used to connect the reagent bottle for injection, so as to ensure the stability and efficiency of the injection process. This also leads to the adapter being produced to adapt to the form of a certain sample detection equipment injection head, and it is difficult to connect with other injection heads, resulting in different injection heads needing to be equipped with different adapters. Once used incorrectly, it will affect the stability of the injection process and increase the cost of using the sample detection equipment. Summary of the invention
[0004] The technical problem to be solved by the present application is how to provide a reagent bottle adapter and a sampling assembly to improve the usability of the reagent bottle adapter.
[0005] The present application provides a reagent bottle adapter, comprising a first sleeve portion and a second sleeve portion that are coaxially connected, a first groove is provided at one end of the first sleeve portion away from the second sleeve portion, the inner diameter of the first groove changes along the axial direction of the first sleeve portion to adapt to different injection heads, a second groove for docking with the reagent bottle is provided at one end of the second sleeve portion away from the first sleeve portion, a through hole connected to the second groove is provided at the bottom of the first groove along the axial direction, an injection needle of the injection head extends into the second groove of the second sleeve portion through the through hole, the inner diameter of at least part of the through hole is smaller than the outer diameter of the injection needle, and a first gap is provided between the inner wall of the second groove and the injection needle to embed the reagent bottle.
[0006] The present application provides an injection assembly, including an injection head and a reagent bottle adapter. The injection head has an injection head body and an injection needle extending from the end of the injection head. The reagent bottle adapter has a first sleeve portion and a second sleeve portion that are coaxially connected, and a first groove is provided at one end of the first sleeve portion away from the second sleeve portion, and the inner diameter of the first groove changes along the axial direction of the first sleeve portion to adapt to different injection head bodies, and a second groove for docking the reagent bottle is provided at one end of the second sleeve portion away from the first sleeve portion, and a through hole connected to the second groove is provided at the bottom of the first groove along the axial direction, and the injection needle extends into the second groove of the second sleeve portion through the through hole, and the inner diameter of at least part of the through hole is smaller than the outer diameter of the injection needle, and there is a first gap between the inner wall of the second groove and the injection needle to embed the reagent bottle.
[0007] Different from the prior art, the present application utilizes a reagent bottle adapter to seal and connect the injection head and the reagent bottle. Since the inner diameter of the first groove changes along the axial direction, it can adapt to different injection heads of different sample detection equipment, thereby improving the usability of the reagent bottle adapter and improving the problem that the reagent bottle adapter cannot be well connected with a variety of injection heads during the injection process, thereby reducing the use cost of the sample detection equipment. BRIEF DESCRIPTION OF THE DRAWINGS
[0008] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. Among them:
[0009] Figure 1 It is a schematic diagram of the assembly structure of an embodiment of the sample injection component of the present application.
[0010] Figure 2 It is a schematic diagram of the structure of the reagent bottle adapter of the present application.
[0011] Figure 3 yes Figure 2 Schematic diagram of the structure of the reagent bottle adapter from another angle.
[0012] Figure 4 It is a schematic diagram of the cross-sectional structure of a reagent bottle adapter equipped with a sleeve.
[0013] Figure 5 yes Figure 4 Schematic diagram of the cross-sectional structure of the reagent bottle adapter. DETAILED DESCRIPTION
[0014] To make the above objects, features, and advantages of the present application more apparent and understandable, the following provides a detailed description of the specific embodiments of the present application in conjunction with the accompanying drawings. It can be understood that the specific embodiments described herein are only for explaining the present application and are not intended to limit the present application. Additionally, it should be noted that for the sake of convenience in description, only the parts related to the present application rather than all the structures are shown in the drawings. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of the present application.
[0015] The terms "first", "second", etc. in the present application are used to distinguish different objects rather than to describe a specific order. In addition, the terms "include" and "be provided with" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product, or device that includes a series of steps or units is not limited to the listed steps or units, but optionally further includes steps or units not listed, or optionally further includes other steps or units inherent to these processes, methods, products, or devices.
[0016] Referring to "embodiments" herein means that the specific features, structures, or characteristics described in connection with the embodiments may be included in at least one embodiment of the present application. The phrase appears in various places in the specification and does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art explicitly and implicitly understand that the embodiments described herein may be combined with other embodiments.
[0017] With the development of medical technology and detection technology, the means for people to detect various biochemical samples have gradually increased, the efficiency and accuracy of sample detection have been continuously improved, and the precision of various medical instruments, devices, or equipment has also been enhanced. Whether the detection results of the test instrument are accurate, ensuring the quality of the quality control material and the sample is a very important link. Once the composition of the quality control material or the sample changes, it will have a great impact on the detection results. When some quality control materials and samples come into contact with the external environment, they are prone to deterioration or contamination due to external factors. To avoid these situations, the quality control materials and samples are usually stored in sealed reagent bottles such as ampoules. However, no matter what reliable method is used for storage, when the quality control material or the sample is introduced into the test card of the test instrument, the quality control material or the sample will inevitably be temporarily exposed to the external environment.
[0018] Directly using the reagent bottle to connect directly to the injection head of the sample detection equipment, after the reagent bottle is opened, the quality control material or sample in the bottle will come into contact with the external environment, and this contact will continue until the test card injection is completed, which is likely to cause the quality control material or sample in the bottle to deteriorate or be contaminated, thereby bringing a negative impact on the accuracy of the test results. Therefore, the common injection process usually uses a reagent bottle adapter to complete the docking of the injection head and the reagent bottle to improve the stability of the docking between the two and reduce the contact between the quality control material or sample and the atmosphere during the injection process.
[0019] For this reason, reagent bottle adapters are generally produced to adapt to the contour shape of the injection head. Once the shape of the injection head changes, the reagent bottle adapter can no longer dock with the injection head. For manufacturers of sample testing equipment, once the shape of the injection head changes, the production mold of the reagent bottle adapter must be updated accordingly, which brings unnecessary production costs. For testers using sample testing equipment, different reagent bottle adapters need to be equipped for different sample testing equipment. Not only is it easy to use the wrong one, affecting the injection stability, but it also leads to an increase in the configuration and use costs of the sample testing equipment, affecting the availability of the sample testing equipment.
[0020] How to provide a reagent bottle adapter and an injection assembly to improve the versatility of the reagent bottle adapter while ensuring the stability of the injection process is a major problem that this application wants to solve.
[0021] See also Figure 1 , Figure 1 This is a schematic diagram of the assembly structure of an embodiment of the sample injection assembly of the present application. The present application provides a reagent bottle adapter 2, through which the reagent bottle and the sample detection device are connected, so that the reagent or sample in the reagent bottle can be passed into the sample detection device to participate in the detection process.
[0022] The reagent bottle adapter 2 may include a first sleeve portion 21 and a second sleeve portion 23 that are coaxially connected. The injection head 1 of the sample detection device is docked with the reagent bottle adapter 2 through the first sleeve portion 21, and the sample bottle is docked with the reagent bottle adapter 2 through the second sleeve portion 23. The injection head 1 may include an injection head body 11 and an injection needle 12.
[0023] Optionally, a first groove 211 may be formed at one end of the first sleeve portion 21 away from the second sleeve portion 23 , and the inner diameter of the first groove 211 varies along the axial direction of the first sleeve portion 21 , so that injection heads 1 with different contour shapes and sizes can be docked in the first groove 211 .
[0024] Specifically, the first groove 211 of the reagent bottle adapter 2 can be a tapered groove. The inner diameter of the tapered groove gradually increases in the direction away from the second socket part 23, and the injection head body 11 with different contour shapes and sizes can abut against different positions on the inner wall of the tapered groove. Of course, the first groove 211 of the reagent bottle adapter 2 can also be a multi-stage stepped groove or the like.
[0025] One end of the second socket part 23 facing away from the first socket part 21 can be provided with a second groove 231. The reagent bottle is docked with the reagent bottle adapter 2 through the second groove 231, and the first socket part 21 and the second socket part 23 are coaxially connected, so as to dock the injection head 1 with the reagent bottle.
[0026] See Figure 4 and Figure 5 , Figure 4 is a schematic cross-sectional structure diagram of the reagent bottle adapter equipped with a sleeve. Figure 5 is Figure 4 is a schematic cross-sectional structure diagram of the reagent bottle adapter in . A through hole 22 communicating with the second groove 231 can be axially opened at the bottom of the first groove 211 along the first socket part 21. The injection needle 12 can extend into the second groove 231 of the second socket part 23 through the through hole 22. There is a first gap 237 between the inner wall of the second groove 231 and the injection needle 12 to embed the reagent bottle, so that the injection needle 12 can obtain the reagent or sample in the reagent bottle.
[0027] Optionally, the inner diameter of at least part of the through hole 22 can be smaller than the outer diameter of the injection needle 12, so as to form an interference fit between the through hole 22 and the outer wall of the injection needle 12, thereby limiting the injection needle 12 in the through hole 22, and further preventing the reagent or sample in the reagent bottle from leaking into the first groove 211 through the through hole 22.
[0028] Furthermore, when the first groove 211 is a tapered groove, the tapered surface of the tapered groove can also guide the injection needle 12 to be docked with the through hole 22.
[0029] In this embodiment, by adding the reagent bottle adapter 2 between the injection head 1 and the reagent bottle, a stable injection path is established between the reagent bottle and the injection head 1, which are difficult to achieve reliable docking due to large size differences. The first groove 211 can adapt to the injection head 1 with different outer contour shapes, enabling the reagent bottle adapter 2 to be docked with a variety of injection heads 1, thereby improving the usability of the reagent bottle adapter 2 well while ensuring the accuracy of the detection results.
[0030] Optionally, a part of the side wall of the second groove 231 extends obliquely in a direction intersecting with the axial direction and away from the first socket part 21 to form an extension part 232, and the extension part 232 is used to support the reagent bottle.
[0031] Specifically, the extending direction of the extension portion 232 is slightly inclined upward relative to the horizontal direction, so that the reagent or sample in the reagent bottle can flow toward the direction close to the through hole 22 under the action of gravity, facilitating the sampling needle 12 to penetrate through the through hole 22 and into the second groove 231 for aspiration.
[0032] Optionally, the angle of the extending direction slightly inclined upward relative to the horizontal direction can be 1° - 7°.
[0033] Optionally, an installation opening 234 can be formed on the upper side of the extension portion 232, and the reagent bottle can enter the second groove 231 through the installation opening 234 and then be embedded in the first gap 237.
[0034] Refer to Figure 2 and Figure 3 , Figure 2 are schematic structural diagrams of the reagent bottle adapter of the present application. Figure 3 is Figure 2 a schematic structural diagram of the reagent bottle adapter from another angle in . The edge 235 of the installation opening 234 can be a smooth curve, which can facilitate the operation of installing the reagent bottle more conveniently, and at the same time can avoid the sharp edge 235 from damaging the operator and the reagent bottle.
[0035] Optionally, the edges 235 of the installation openings 234 located on both sides of the extension portion 232 can be gentle line segments parallel to the axial direction to better fix and support the reagent bottle.
[0036] Optionally, a limiting surface 233 is provided on the inner wall of the extension portion 232, and the contour shape of the limiting surface 233 is the same as the outer contour shape of the reagent bottle, which can play a role in supporting and limiting the reagent bottle, thereby improving the stability of the docking between the reagent bottle and the reagent bottle adapter 2.
[0037] Furthermore, the lower side edge 2351 of the end of the extension portion 232 far from the first socket portion 21 can protrude upward to form a flange 236, and the flange 236 is used to abut against the bottom of the reagent bottle to limit the reagent bottle in the second groove 231.
[0038] Optionally, considering that the extension portion 232 is slightly inclined upward relative to the horizontal direction, the reagent bottle installed in the second groove 231 is also inclined at a certain angle, and the contour shape of the flange 236 can adapt to the contour shape of the bottom of the reagent bottle to better limit the reagent bottle.
[0039] Optionally, the height of the flange 236 can be lower than the edges 2352 at both sides of the extension portion 232 to facilitate the installation or removal of the reagent bottle.
[0040] Optionally, the flange 236 can be a flexible component, which can deform under the extrusion of the reagent bottle to facilitate the installation or removal of the reagent bottle.
[0041] When using the reagent bottle adapter 2 to dock the sample detection device and the reagent bottle, if the part of the reagent bottle mouth other than the sampling needle 12 is sealed and sampling is carried out while ensuring that the liquid does not come into contact with the external space, although the contact between the reagent or sample and the external space is reduced, the vacuum degree in the reagent bottle will gradually increase as the reagent is introduced into the sample detection device, which may cause difficulties in subsequent sampling.
[0042] Optionally, a communication groove 238 communicating the through hole 22 with the space outside the mounting port 234 may be formed in the inner wall of the remaining side wall 2312 of the second groove 231 of the second socket part 23. The communication groove 238 is configured to communicate the inside of the reagent bottle with the external space after the reagent bottle is installed, so as to balance the air pressure in the reagent bottle while reducing the contact between the reagent or sample and the external space, thereby improving the efficiency and stability of the sampling process.
[0043] Refer to Figure 3 、 4 For mass-produced reagent bottles, the outer contour shape is usually relatively smooth or close to a cylinder, and it is easy to slip when the operator puts the reagent bottle into or takes it out of the reagent bottle adapter 2, resulting in leakage of the sample or reagent. Therefore, an enhancing part 239 for the operator to hold the reagent bottle adapter may also be provided on the outer wall of the extending part 232.
[0044] The enhancing part 239 may be recessed relative to the outer surface of the extending part 232 towards the direction close to the second groove 231 to form a groove structure for increasing the friction when holding the extending part 232, facilitating the operator to load the reagent bottle into the second groove 231.
[0045] Optionally, a support surface may also be provided on the outer surface of the reagent bottle adapter 2, and the contour shape of the support surface matches the surface of the sample detection device, so that the reagent bottle adapter 2 and the sample bottle can be stably supported on the surface of the test instrument by using the support surface, and there is no need for the operator to manually support the reagent bottle adapter 2 to complete the sampling process.
[0046] Optionally, the support surface and / or the enhancing part 239 of the reagent bottle adapter 2 may be treated to increase the roughness, thereby improving the stability of the sampling process.
[0047] Optionally, since the sample or reagent may leak into the second groove 231, the reagent bottle adapter 2 can be sterilized before sampling and is made of a material that is not prone to react with the sample or reagent.
[0048] Furthermore, the reagent bottle adapter 2 provided in this application may further include a sleeve 24. One end of the sleeve 24 is sleeved on the end of the sampling needle 12, and the other end extends beyond the sampling needle 12, so as to extend the length of the sampling needle 12 and avoid the situation that the sampling needle 12 is not long enough to contact the sample or reagent.
[0049] Optionally, the sleeve 24 can be installed at one end of the sampling needle 12 extending into the second groove 231 to extend the length of the sampling needle 12 for facilitating the aspiration of the reagent or sample in the reagent bottle.
[0050] Optionally, a docking groove 2311 can also be provided on one side of the second groove 231 close to the through hole 22. One end of the sleeve 24 can be installed in the docking groove 2311, and the other end extends towards the reagent or sample in the reagent bottle.
[0051] Specifically, the diameter of the docking groove 2311 can be larger than the diameter of the through hole 22 at one end close to the first socket part 21 and smaller than the diameter of the sleeve 24 to fix the sleeve 24.
[0052] The present application can also provide a sampling assembly, including a sampling head 1 and a reagent bottle adapter 2. The sampling head 1 has a sampling head body 11 and a sampling needle 12 extending from the end of the sampling head 1. The reagent bottle adapter 2 has a first socket part 21 and a second socket part 23 connected coaxially.
[0053] Wherein, a first groove 211 can be opened at one end of the first socket part 21 facing away from the second socket part 23. The inner diameter of the first groove 211 varies along the axial direction of the first socket part 21 to adapt to different sampling head bodies 11. One end of the second socket part 23 facing away from the first socket part 21 has a second groove 231 for docking with the reagent bottle. A through hole 22 communicating with the second groove 231 is axially opened at the bottom of the first groove 211, and the sampling needle 12 extends into the second groove 231 of the second socket part 23 through the through hole 22.
[0054] Optionally, the inner diameter of at least part of the through hole 22 is smaller than the outer diameter of the sampling needle 12, and there is a first gap 237 between the inner wall of the second groove 231 and the sampling needle 12 for embedding the reagent bottle.
[0055] The above are only the embodiments of the present application, and do not limit the patent scope of the present application accordingly. All equivalent structural or equivalent process transformations made by using the content of the specification and drawings of the present application, or directly or indirectly applied in other related technical fields, are equally included in the patent protection scope of the present application.
Claims
1. A reagent bottle adapter, characterized in that, include: A first sleeve portion and a second sleeve portion are coaxially connected, wherein a first groove is provided at one end of the first sleeve portion away from the second sleeve portion, and an inner diameter of the first groove changes along the axial direction of the first sleeve portion to adapt to different injection heads; a second groove is provided at one end of the second sleeve portion away from the first sleeve portion to dock with a reagent bottle, a through hole connected to the second groove is provided at the bottom of the first groove along the axial direction, and an injection needle of the injection head extends into the second groove of the second sleeve portion through the through hole, and the inner diameter of at least part of the through hole is smaller than the outer diameter of the injection needle, and a first gap is provided between the inner wall of the second groove and the injection needle to embed the reagent bottle.
2. The reagent bottle adapter according to claim 1, wherein include: The first groove is a tapered groove, the inner diameter of which gradually increases in a direction away from the second sleeve portion, and the injection head body abuts against the inner wall of the tapered groove.
3. The reagent bottle adapter according to claim 1, wherein, include: A portion of the side wall of the second groove obliquely extends along a direction intersecting the axial direction and away from the first sleeve portion to form an extension portion, and the extension portion is used to support the reagent bottle.
4. The reagent bottle adapter according to claim 3, wherein, include: An installation opening is provided on the upper side of the extension portion, the edge of the installation opening is a smooth curve, and the edges located at both sides of the extension portion are gentle line segments parallel to the axial direction.
5. The reagent bottle adapter according to claim 4, characterized in that, include: The lower edge of one end of the extending portion away from the first sleeve portion protrudes toward the upper side to form a flange, and the flange is used to abut against the bottom of the reagent bottle to limit the reagent bottle in the second groove.
6. The reagent bottle adapter according to claim 5, characterized in that, The flange is lower than the edges at both sides of the extension portion.
7. The reagent bottle adapter according to claim 4, characterized in that, include: A connecting groove connecting the through hole and the space outside the installation port is formed on the inner wall of the remaining part of the side wall of the second groove of the second sleeve portion, and the connecting groove is configured to connect the inside of the reagent bottle with the external space after the reagent bottle is installed.
8. The reagent bottle adapter according to claim 3, wherein, include: The inner wall of the extension portion is provided with a limiting surface, and the contour shape of the limiting surface is the same as the outer contour shape of the reagent bottle, so as to support and limit the reagent bottle.
9. The reagent bottle adapter according to claim 1, wherein The through hole is configured so that the injection needle of the injection head extends into the second groove of the second sleeve portion through the through hole, the inner diameter of at least part of the through hole is smaller than the outer diameter of the injection needle, and there is a first gap between the inner wall of the second groove and the injection needle to embed the reagent bottle, and the reagent bottle adapter also includes: A sleeve, one end of which is sleeved on the end of the injection needle and the other end of which extends beyond the injection needle. A docking groove is also provided on the side of the second groove close to the through hole. The diameter of the docking groove is larger than the diameter of the through hole close to one end of the first sleeve connection part and smaller than the diameter of the sleeve.
10. An injection component, characterized in that, include: An injection head, comprising an injection head body and an injection needle extending from an end of the injection head; Reagent bottle adapter, having a first socket part and a second socket part connected coaxially. One end of the first socket part facing away from the second socket part is provided with a first groove, and the inner diameter of the first groove varies along the axial direction of the first socket part to adapt to different sample injection head bodies. One end of the second socket part facing away from the first socket part has a second groove for docking with a reagent bottle. A through hole communicating with the second groove is axially opened at the bottom of the first groove. The sampling needle extends into the second groove of the second socket part through the through hole. The inner diameter of at least part of the through hole is smaller than the outer diameter of the sampling needle. There is a first gap between the inner wall of the second groove and the sampling needle to embed a reagent bottle.