Sample analyzer

Abstract

The invention discloses a sample analyzer which comprises a sample supply mechanism, a sample separate injection mechanism, a reagent supply mechanism, a reagent separate injection mechanism and a determination mechanism. Wherein the reagent supply mechanism comprises a storage component provided with reagent storage positions and a reagent container transfer device, the reagent container transfer device is used for transferring reagent containers stored on the reagent storage positions to a liquid suction position for liquid suction, and the height of the liquid suction position is lower than that of the reagent storage position located at the highest height. The lower liquid absorption level is beneficial to reducing the height of the reagent separate injection mechanism, so that the height of the whole machine is reduced, and the overall size of the sample analyzer is small.

Description

Technical Field

[0001] The present invention relates to the field of sample analysis, and particularly to a sample analyzer. Background Art

[0002] In the reagent storage of an existing sample analyzer, in order to enable a liquid suction assembly to periodically suck the reagent in a reagent bottle in the reagent storage, it is necessary to move the liquid suction assembly above the reagent storage, and then insert the liquid suction needle of the liquid suction assembly into the reagent bottle in the reagent storage to suck the reagent. After the liquid suction is completed, the reagent needle withdraws from the reagent storage. The existing reagent suction scheme is to perform liquid suction above the reagent storage. When the height of the reagent storage is relatively high, this scheme requires a relatively high height of the liquid suction assembly, resulting in a relatively high overall height and large volume of the analyzer. Summary of the Invention

[0003] The first object of the present invention is to provide a sample analyzer, which aims to solve the technical problem of the relatively large volume of the sample analyzer.

[0004] To achieve the above object, the present invention provides a sample analyzer, including:

[0005] A sample supply mechanism for supplying samples;

[0006] A sample dispensing mechanism for dispensing samples into reaction vessels;

[0007] A reagent supply mechanism for supplying reagents;

[0008] A reagent dispensing mechanism for sucking the reagent in a reagent container at a liquid suction position and discharging the sucked reagent into a reaction vessel at a discharge position;

[0009] A measurement mechanism for measuring at least a test solution made of the sample and the reagent in the reaction vessel to obtain a measurement result;

[0010] Wherein, the reagent supply mechanism includes:

[0011] A storage member provided with a plurality of reagent storage positions for placing reagent containers, the plurality of reagent storage positions are arranged in a first direction, and at least two reagent storage positions are stacked in the vertical direction, and the first direction is different from the vertical direction;

[0012] A reagent container transfer device for transferring the reagent container stored in the reagent storage position to the liquid suction position for liquid suction;

[0013] Wherein, the height of the liquid suction position is lower than the height of the reagent storage position with the highest height.

[0014] As an implementation manner, the liquid suction position is located outside the projection area of the reagent storage position in the vertical direction.

[0015] As an implementation manner, the reagent supply mechanism includes a housing, the housing forms a receiving cavity, the reagent storage position is arranged inside the receiving cavity, the liquid suction position is located outside the receiving cavity, and the housing is further provided with an opening which communicates the inside and the outside of the receiving cavity for the reagent container transfer device to pass through when transferring the reagent container stored on the reagent storage position to the liquid suction position.

[0016] As an implementation manner, the reagent container transfer device includes a first reagent container transfer component and a second reagent container transfer component. The first reagent container transfer component is used for transferring the reagent container located at the reagent storage position to a first position, and the second reagent container transfer component is used for transferring the reagent container located at the first position to the liquid suction position.

[0017] As an implementation manner, the second reagent container transfer component includes a moving component and a reagent container carrying component. The reagent container carrying component is used for carrying the reagent container transferred by the first reagent container transfer component at the first position and carrying out liquid suction on the reagent container, and the moving component is used for driving the reagent container carrying component to move between the first position and the liquid suction position.

[0018] As an implementation manner, the moving direction of the second reagent container transfer component between the first position and the liquid suction position is a second direction, and the second direction is a horizontal direction and is perpendicular to the first direction.

[0019] As an implementation manner, the first position is located within the projection area of the reagent storage position in the vertical direction, and / or the first position is located inside the receiving cavity.

[0020] As an implementation manner, the second reagent container transfer component moves in a straight line along the second direction, the reagent dispensing mechanism moves in a straight line along a third direction, and the movement track of the second reagent container transfer component intersects and is perpendicular to the movement track of the reagent dispensing mechanism.

[0021] As an implementation manner, the liquid suction position is located within the projection area of the storage member in the vertical direction.

[0022] As an implementation manner, the liquid discharge position is outside the projection area of the reagent storage position in the vertical direction; or, the sample analyzer further includes a reaction vessel transfer device, the liquid discharge position is within the projection area of the reagent storage position in the vertical direction, and the reaction vessel transfer device is configured to transfer the reaction vessel that has completed liquid discharge at the liquid discharge position to outside the projection area of the reagent storage position in the vertical direction.

[0023] As an implementation manner, the reagent supply mechanism includes a housing, the housing forms an accommodation cavity, the storage member and the reagent container transfer device are arranged in the accommodation cavity, and the liquid suction position is inside the accommodation cavity.

[0024] As an implementation manner, the housing is provided with an opening, the opening communicates the inside and the outside of the accommodation cavity, the liquid discharge position is outside the accommodation cavity, and the opening is used for the reagent dispensing mechanism to move through between the liquid suction position and the liquid discharge position; or, the sample analyzer further includes a reaction vessel transfer device, the housing is provided with an opening, the opening communicates the inside and the outside of the accommodation cavity, the liquid discharge position is inside the accommodation cavity, and the reaction vessel transfer device is configured to transfer the reaction vessel that has completed liquid discharge at the liquid discharge position to the outside of the accommodation cavity through the opening.

[0025] As an implementation manner, the storage member includes at least two sub-storage members stacked in the vertical direction, the sub-storage members extend in a first direction and are provided with a plurality of partition plates in the first direction, and a plurality of reagent storage positions arranged in the first direction are formed between the partition plates.

[0026] As an implementation manner, the first direction is a horizontal direction perpendicular to the vertical direction.

[0027] The second object of the present invention is to provide a sample analyzer, which includes:

[0028] A sample supply mechanism for supplying a sample;

[0029] A sample dispensing mechanism for dispensing the sample into a reaction vessel;

[0030] A reagent supply mechanism for supplying a reagent;

[0031] A reagent dispensing mechanism for sucking the reagent in the reagent container at the liquid suction position and discharging the sucked reagent into the reaction vessel at the liquid discharge position;

[0032] A measurement mechanism for measuring the test liquid made of at least the sample and the reagent in the reaction vessel to obtain a measurement result;

[0033] Wherein, the reagent supply mechanism includes:

[0034] A storage component is provided with a plurality of reagent storage positions for placing reagent containers. The multiple reagent storage positions are arranged in a first direction, and at least two reagent storage positions are stacked in the vertical direction. The first direction is different from the vertical direction.

[0035] A reagent container transfer device is used to transfer the reagent container stored in the reagent storage position to the liquid suction position for liquid suction.

[0036] A housing forms an accommodation cavity. The reagent storage position is arranged inside the accommodation cavity, and the liquid suction position is located outside the accommodation cavity. The housing is also provided with an opening that communicates the inside and outside of the accommodation cavity for the reagent container transfer device to pass through when transferring the reagent container stored in the reagent storage position to the liquid suction position.

[0037] As an implementation manner, the reagent container transfer device includes a first reagent container transfer component and a second reagent container transfer component. The first reagent container transfer component is used to transfer the reagent container located at the reagent storage position to a first position, and the second reagent container transfer component is used to transfer the reagent container located at the first position to the liquid suction position. Among them, the first position is located outside the accommodation cavity.

[0038] The sample analyzer provided by the present invention is provided with a liquid suction position lower than the highest reagent storage position, which is beneficial to reducing the overall height of the sample analyzer and making the overall volume of the sample analyzer smaller. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on the structures shown in these drawings without creative efforts.

[0040] Figure 1 is a schematic diagram of the sample analyzer provided by the embodiment of the present invention;

[0041] Figure 2 is a schematic diagram of the reagent supply mechanism provided by the embodiment of the present invention;

[0042] Figure 3 is a schematic diagram of the reagent supply mechanism provided by the embodiment of the present invention;

[0043] Figure 4 is a schematic diagram of the reagent supply mechanism provided by the embodiment of the present invention;

[0044] Figure 5 is a schematic structural diagram of a first reagent container transfer component provided by an embodiment of the present invention;

[0045] Figure 6 is a schematic structural diagram of a reagent container transfer device provided by an embodiment of the present invention;

[0046] Figure 7 is a schematic structural diagram of a storage component provided by an embodiment of the present invention.

[0047] Explanation of reference numerals in the drawings: 10, sample analyzer; 11, sample supply mechanism; 12, sample dispensing mechanism; 13, reagent supply mechanism; 131, storage component; 1311, sub-storage component; 1312, partition; 132, reagent container transfer device; 1321, first reagent container transfer component; 1321a, first-direction movement component; 1321b, vertical-direction movement component; 1321c, second-direction movement component; 1321d, clamping device; 1322, second reagent container transfer component; 1322a, moving component; 1322b, reagent container carrying component; 1322b', reagent container carrying component; 133, housing; 1331, opening; 14, reagent dispensing mechanism; 15, measuring mechanism; 16, incubation mechanism; 17, magnetic separation mechanism; 20, reagent container. Detailed implementation manners

[0048] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts belong to the scope of protection of the present invention.

[0049] It should be noted that all directional indications (such as up, down, left, right, front, back...) in the embodiments of the present invention are only used to explain the relative position relationship and movement conditions between components in a specific posture. If the specific posture changes, the directional indications will also change accordingly.

[0050] It should also be noted that when an element is referred to as "fixed to" or "disposed on" another element, it can be directly on the other element or there may be an intermediate element at the same time. When an element is referred to as "connected" to another element, it can be directly connected to the other element or indirectly connected to the other element through an intermediate element.

[0051] In addition, the descriptions involving "first", "second", etc. in the present invention are for descriptive purposes only, and should not be construed as indicating or implying their relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions between various embodiments may be combined with each other, but it must be based on the fact that those skilled in the art can implement them. When the combination of technical solutions results in contradictions or cannot be implemented, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0052] Embodiment 1:

[0053] Please refer to Figures 1 to 6 , an embodiment of the present invention provides a sample analyzer 10, including a sample supply mechanism 11 for supplying a sample; a sample dispensing mechanism 12 for dispensing the sample into a reaction vessel; a reagent supply mechanism 13 for supplying a reagent; a reagent dispensing mechanism 14 for sucking the reagent in a reagent container at a liquid suction level and discharging the sucked reagent into a reaction vessel at a liquid discharge level; and a measurement mechanism 15 for measuring at least a test solution made of the sample and the reagent in the reaction vessel to obtain a measurement result.

[0054] In some embodiments, please refer to Figures 2 to 4 , the reagent supply mechanism 13 includes a storage member 131. The storage member 131 is provided with a plurality of reagent storage positions for placing reagent containers 20. The plurality of reagent storage positions are arranged in a first direction, and at least two reagent storage positions are stacked in the vertical direction. The first direction is different from the vertical direction; a reagent container transfer device 132 for transferring the reagent container 20 stored in the reagent storage position to the liquid suction level for liquid suction; wherein, the height of the liquid suction level is lower than the height of the reagent storage position with the highest height. In this application, the height of the liquid suction level is set lower than the highest reagent storage position, which can reduce the overall height of the sample analyzer and make the overall volume of the sample analyzer smaller.

[0055] In some embodiments, the height of the liquid suction level is the same as the height of one of the reagent storage positions lower than the highest reagent storage position. Since reagent storage positions can also be arranged at the same height as the liquid suction level, the number of reagent storage positions can be expanded.

[0056] In some embodiments, the liquid suction level is located outside the projection area of the reagent storage position in the vertical direction, which can effectively achieve structural avoidance between the reagent dispensing mechanism and the reagent supply mechanism, thereby further reducing the space occupied by the instrument.

[0057] In some embodiments, please refer to Figure 3 , Figure 4, the reagent supply mechanism 13 includes a housing 133. The housing 133 forms an accommodation cavity. The reagent storage position is arranged inside the accommodation cavity, and the liquid suction position is outside the accommodation cavity. The housing 133 is also provided with an opening 1331. The opening 1331 communicates the inside and the outside of the accommodation cavity, so that the reagent container transfer device 132 can pass through when transferring the reagent container 20 stored at the reagent storage position to the liquid suction position. It can effectively realize the structural avoidance between the reagent dispensing mechanism and the reagent supply mechanism, thereby further reducing the space occupied by the instrument.

[0058] In some embodiments, the storage member 131 is fixedly connected to the housing 133, and the storage member 131 remains fixed during the process of transferring the reagent container 20. In some embodiments, the storage members 131 are all arranged on the same inner side surface of the housing 131.

[0059] In some embodiments, the storage member 131 and the opening 1331 are arranged on the same side surface of the housing 133.

[0060] In some embodiments, the reagent supply mechanism 13 includes a housing 133 and a liquid suction position housing. The housing 133 forms an accommodation cavity, and the liquid suction position housing forms a liquid suction position cavity. The housing 133 is connected to the liquid suction position housing, and the housing 133 and the liquid suction position housing are communicated through the opening 1331. The storage member 131 is arranged in the accommodation cavity formed by the housing 133, and the storage member 131 is arranged on the inner side surface of the side of the housing 133 connected to the liquid suction position housing. The liquid suction position is arranged in the liquid suction position cavity formed by the liquid suction position housing. The reagent container transfer device 132 can move between the accommodation cavity and the liquid suction position cavity to transfer the reagent container 20 from the accommodation cavity to the liquid suction position located in the liquid suction position cavity. Arranging the liquid suction position inside the liquid suction position housing is beneficial to maintaining the temperature inside the reagent supply mechanism and avoiding the generation of condensed water.

[0061] In some embodiments, openings are provided at the top of the second housing and the position of the liquid suction position. The openings are used for the pipetting needle of the reagent dispensing mechanism to pass through to aspirate the reagent. In some embodiments, the positions and quantities of the openings correspond to the positions and quantities of the liquid suction ports on the reagent container 20 located at the liquid suction position.

[0062] In some embodiments, the reagent container transfer device includes a first reagent container transfer component 1321 and a second reagent container transfer component 1322. The first reagent container transfer component 1321 is used to transfer the reagent container 20 located at the reagent storage position to a first position, and the second reagent container transfer component is used to transfer the reagent container 20 located at the first position to the liquid suction position.

[0063] In some embodiments, such as Figure 5As shown, the first reagent container transfer component 1321 includes a clamping device 1321d and a three-dimensional motion device. The clamping device is connected to the three-dimensional motion device, and the three-dimensional motion device drives the clamping device to move in a three-dimensional space so that the clamping device can move between each reagent storage position and the first position. The three-dimensional motion device drives the clamping device to move in three directions, and the three directions are perpendicular to each other.

[0064] In some embodiments, the three-dimensional motion device is installed in the accommodation cavity formed by the housing.

[0065] In some embodiments, the directions in which the three-dimensional motion device drives the clamping device to move include a first direction, i.e., the arrangement direction of the reagent storage positions, a second direction, and a vertical direction. In some embodiments, both the first direction and the second direction are horizontal directions.

[0066] In some embodiments, the three-dimensional motion device includes a first-direction motion component 1321a, a second-direction motion component 1321c, and a vertical-direction motion component 1321b. The first-direction motion component 1321a is connected to the inner side surface of the housing 133. The first-direction motion component 1321a includes a slide rail, a drive source, and a transmission member. The slide rail of the first-direction motion component 1321a extends along the first direction. The transmission member is respectively connected to the vertical-direction motion component and the drive source of the first-direction motion component 1321a, and the vertical-direction motion component 1321b is slidably connected to the slide rail of the first-direction motion component 1321a, so that under the drive of the drive source of the first-direction motion component 1321a, the vertical-direction motion component 1321b moves along the first direction.

[0067] In some embodiments, the number of slide rails of the first-direction moving member 1321a is two, making the entire three-dimensional moving device more stable. The two slide rails are distributed in the vertical direction, with the lower slide rail below the lowest reagent storage position and the upper slide rail above the highest reagent storage position. The vertical-direction moving member 1321b is slidably connected to the upper and lower slide rails respectively. The vertical-direction moving member 1321b includes a main body portion, a guide rail, and a driving source. The main body portion of the vertical-direction moving member 1321b extends in the vertical direction, and both ends of the main body portion of the vertical-direction moving member are connected to the upper and lower guide rails respectively. The guide rail of the vertical-direction moving member 1321b extends in the vertical direction and is disposed on the main body portion of the vertical-direction moving member 1321b. The second-direction moving member 1321c is connected to the guide rail of the vertical-direction moving member 1321b and the driving source of the vertical-direction moving member 1321b respectively. The driving source of the vertical-direction moving member 1321b drives the second-direction moving member 1321c to move in the vertical direction along the guide rail of the vertical-direction moving member 1321b. The second-direction moving member 1321c includes a main body portion, a guide rail, and a driving source. The main body portion of the second-direction moving member 1321c is connected to the guide rail of the vertical-direction moving member. The guide rail of the second-direction moving member 1321c extends in the second direction and is connected to the clamping device 1321d and the main body portion of the second-direction moving member 1321c respectively. The clamping device 1321d is also connected to the driving source of the second-direction moving member 1321c. Driven by the driving source of the second-direction moving member 1321c, the clamping device 1321d moves in the second direction along the guide rail of the second-direction moving member 1321c. In summary, the clamping and loading device 1321d can move in the first direction, the second direction, and the vertical direction under the drive of the three-dimensional moving device, that is, it can move in three-dimensional space, and the range where the three-dimensional moving device drives the clamping device to move includes all reagent storage positions and the first position.

[0068] In some embodiments, the second reagent container transfer member 1322 includes a moving member 1322a and a reagent container carrying member 1322b. The reagent container carrying member 1322b is used to carry the reagent container 20 transferred by the first reagent container transfer member 1321 at the first position and carry the reagent container 20 for liquid suction. The moving member 1322a is used to drive the reagent container carrying member 1322b to move between the first position and the liquid suction position.

[0069] The first position is a transfer position, that is, the first reagent container transfer device 1321 transfers the reagent container 20 to the first position first, and then the second reagent container transfer device 1322 transfers the reagent container 20 at the first position to the liquid aspiration position. Similarly, after the reagent container 20 completes the liquid aspiration at the liquid aspiration position, the second reagent container transfer device 1322 transfers the reagent container 20 from the liquid aspiration position to the first position, and then the first reagent container transfer device transfers the reagent container back to the corresponding reagent storage position.

[0070] In some embodiments, when the reagent container carrying component 1322 b of the second reagent container transfer device 1322 is located at the first position, the first reagent container transfer device 1321 transfers the reagent container 20 to the reagent container carrying component 1321 b of the second reagent container transfer device 1322 .

[0071] In some embodiments, please refer to Figure 6 , Figure 6 This is a schematic diagram of the reagent container in the first position and the liquid aspiration position on the second reagent container transfer mechanism. This figure is intended to better illustrate the state of the second reagent container transfer device at the first position and the liquid aspiration position. It can be understood that the difference between the reagent container carrying part 1332b and the reagent container carrying part 1332b' is only the difference in position, wherein the reagent container carrying part 1332b' is located in the first position, and the reagent container carrying part 1332b is located in the liquid aspiration position.

[0072] In some embodiments, the moving part 1322a includes a conveying track and a driving mechanism, the driving mechanism is arranged on the conveying track, and the reagent container carrying part 1332b is slidably connected to the conveying track, so that the moving part 1322a can slide on the conveying track. The driving mechanism is arranged on the conveying track, the driving mechanism is transmission-connected to the reagent container carrying part 1322b, and the driving mechanism is used to drive the reagent container carrying part 1322b to reciprocate on the conveying track to move the reagent container carrying part 1332b between the first position and the liquid aspiration position.

[0073] In some embodiments, a transmission chain is further provided on the transfer track along the moving direction of the reagent container carrying member 1332b. A mixing structure is provided on the reagent container carrying member 1332b, and the mixing structure is used to mix the magnetic bead reagent in the reagent container 20 placed on the reagent container carrying member 1332b. The mixing mechanism includes a cooperating portion and a transmission portion that cooperate with the reagent container. The transmission portion includes a gear structure, and the gear structure in the transmission portion meshes with the transmission chain on the transfer track. When the reagent container carrying member moves along the transfer track driven by the driving mechanism, the transfer chain cooperates with the gear structure of the transmission portion, causing the gear structure to rotate, thereby driving the cooperating portion that cooperates with the reagent container 20 to rotate, so as to mix the magnetic bead reagent in the reagent container placed on the reagent container carrying member 1332b during the process of transferring the reagent container 20.

[0074] In some embodiments, the direction in which the second reagent container transfer member 1322 moves between the first position and the liquid suction position is the second direction, and the second direction is a horizontal direction and perpendicular to the first direction.

[0075] In some embodiments, the extending direction of the transfer track is the second direction. Driven by the driving mechanism, the reagent container carrying member 1322b moves along the transfer track in the second direction. The second direction is a horizontal direction and perpendicular to the first direction.

[0076] In some embodiments, the first position is within the projection area of the reagent storage position along the vertical direction. In some embodiments, the first position and the reagent storage positions at non-maximum heights are arranged along the first direction. In some embodiments, the first position and the reagent storage position are arranged along the vertical direction, and the first position is lower than the reagent storage position at the maximum height.

[0077] In some embodiments, the first position is inside the accommodating cavity. In some embodiments, the first position is not within the projection area of the reagent storage position in the vertical direction, is inside the accommodating cavity, and the first position is within the movement range of the three-dimensional motion device.

[0078] In some embodiments, the first position is within the projection area of the reagent storage position along the vertical direction and is inside the accommodating cavity.

[0079] In some embodiments, the second reagent container transfer member 1332 moves in a straight line along the second direction, and the reagent dispensing mechanism 14 moves in a straight line along the third direction. The movement trajectories of the second reagent container 20 transfer member and the reagent dispensing mechanism 14 cross and are perpendicular, which is beneficial to reducing the occupied area of the reagent supply mechanism 13 and the reagent dispensing mechanism 14 on the plane, making the whole sample analyzer 10 more compact.

[0080] In some embodiments, the third direction is the same as the first direction, the second direction is the horizontal direction and is perpendicular to the first direction. In some embodiments, after the reagent dispensing mechanism 14 sucks the reagent at the suction level, it moves in a straight line along the third direction and then discharges it into the reaction vessel located at the discharge level.

[0081] In some embodiments, the third direction is the horizontal direction.

[0082] In some embodiments, the suction level is within the projection area of the storage member along the vertical direction, and the discharge level is outside the projection area of the reagent storage position along the vertical direction. After the reagent dispensing mechanism 14 sucks the reagent at the suction level, it transfers to the discharge level and discharges the sucked reagent into the reaction vessel.

[0083] In some embodiments, the sample analyzer 10 further includes a reaction vessel transfer device. The suction level is within the projection area of the storage member along the vertical direction, and the discharge level is within the projection area of the reagent storage position along the vertical direction. The reaction vessel transfer device is used to transfer the reaction vessel that has completed liquid discharge at the discharge level to outside the projection area of the reagent storage position along the vertical direction.

[0084] In some embodiments, the reagent supply mechanism 13 includes a housing 133. The housing 133 forms an accommodation cavity. The storage member 131 and the reagent container transfer device 132 are arranged in the accommodation cavity, and the suction level is inside the accommodation cavity. The housing 133 is provided with an opening 1331. The opening 1331 communicates the inside and the outside of the accommodation cavity. The discharge level is outside the accommodation cavity. The opening 1331 is used for the reagent dispensing mechanism to move through between the suction level and the discharge level.

[0085] In some embodiments, the reagent supply mechanism 13 includes a housing 133. The housing 133 forms an accommodation cavity. The storage member 131 and the reagent container transfer device 132 are arranged in the accommodation cavity, and the suction level is inside the accommodation cavity. The sample analyzer 10 further includes a reaction vessel transfer device. The housing 133 is provided with an opening 1331. The opening 1331 communicates the inside and the outside of the accommodation cavity. The discharge level is inside the accommodation cavity. The reaction vessel transfer device is used to transfer the reaction vessel that has completed liquid discharge at the discharge level to the outside of the accommodation cavity through the opening.

[0086] In some embodiments, please refer to Figure 7 , the storage member 131 includes at least two sub-storage members 1311 stacked in the vertical direction. The sub-storage members 1311 extend along the first direction and are provided with a plurality of partition plates 1312 in the first direction. A plurality of reagent storage positions arranged along the first direction are formed between the partition plates 1312. In some embodiments, the partition plates 1312 are integrally formed with the sub-storage members 1311.

[0087] In some embodiments, the first direction is a horizontal direction perpendicular to the vertical direction.

[0088] In some embodiments, the reagent container transfer device 132 includes a clamping device 1321d and a three-dimensional motion device. The three-dimensional motion device drives the clamping device 1321d to transfer the reagent container 20 from the reagent storage position to the liquid suction position, and the clamping device 1321d clamps the reagent container 20 at the liquid suction position to complete the reagent dispensing mechanism 14 sucking the reagent.

[0089] In some embodiments, the reagent container 20 carried at the reagent storage position includes at least two cavities and a lid that mates with the top of the cavities. The lid is provided with a liquid suction port for the reagent dispensing mechanism to suck the liquid. One of the cavities contains a magnetic bead reagent. In some embodiments, the reagent container 20 includes one magnetic bead reagent cavity and three non-magnetic bead reagent carrying cavities. The reagent container 20 includes a reagent container body and a rotatable container. The rotatable container is rotatably connected to the reagent container body, so that the rotatable container can rotate around its axis relative to the reagent container body. Among them, the rotatable container forms a cavity for loading the magnetic bead reagent, and at least one reagent cavity for loading the reagent is formed in the reagent container body part. The reagent cavity is used for loading non-magnetic bead reagents. The rotatable container includes a connecting part and a stirring part. The connecting part is rotatably connected to the reagent container body. Along the direction from the lid to the bottom of the cavity, the stirring part is located below the connecting part. The stirring part cooperates with the mixing structure on the reagent supply mechanism. Driven by the mixing mechanism, the stirring part rotates to drive the rotatable container to rotate, so as to mix the magnetic bead reagent contained in the cavity of the rotatable container. Symmetrically arranged concave parts are provided on the two outer sides of the reagent container 20 along the cavity arrangement direction. The concave parts are used to cooperate with the convex parts on the clamping device 20 when the clamping device 1321d clamps the reagent container 20, so that the clamping device 1321d clamps the reagent container 20 more firmly.

[0090] In some embodiments, symmetrically arranged convex parts may also be provided on the two outer sides of the reagent container 20 along the cavity arrangement direction. Correspondingly, concave parts that cooperate with the convex parts provided on the two outer sides of the reagent container 20 are provided on the clamping device 1321d. In some embodiments, the aforementioned concave or convex parts of the reagent container 20 are provided on the outer side surface part corresponding to the non-rotatable container.

[0091] The operation process of the sample analyzer will be introduced below, taking an immunoassay analyzer as an example. In addition to the sample supply mechanism 11, sample dispensing mechanism 12, reagent supply mechanism 13, reagent dispensing mechanism 14, and measurement mechanism 15 mentioned above, the immunoassay analyzer further includes an incubation mechanism 16 and a magnetic separation mechanism 17. Taking a common scenario in the immunoassay analyzer as an example, the sample dispensing mechanism 12 dispenses the sample supplied by the sample supply mechanism 11 into the reaction vessel, and the reagent dispensing mechanism 14 dispenses the reagent supplied by the reagent supply mechanism 13 into the reaction vessel to form a mixed solution with the sample.

[0092] The process of the reagent dispensing mechanism 14 dispensing the reagent includes: the clamping device 1321d moves to the reagent storage position corresponding to the test item under the drive of the three-dimensional motion device, clamps the reagent container 20 carried on the reagent storage position and transfers it to the first position, and the second reagent container transfer device 1322 transfers the reagent container 20 located at the first position to the liquid suction position, and the reagent dispensing mechanism 14 aspirates the reagent in the reagent container located at the liquid suction position.

[0093] After completing the dispensing of the reagent and the sample, the mixed solution of the reagent and the sample is transferred to the incubation mechanism 16 for incubation. After the incubation is completed, the mixed solution of the sample and the reagent is magnetically separated and cleaned in the magnetic separation mechanism 17. After the magnetic separation cleaning is completed, a signal reagent is added, and finally the measurement mechanism 15 performs the measurement.

[0094] Example Two:

[0095] The sample analyzer 10 provided in this embodiment is mainly different from that in Example One in that the liquid suction position is outside the accommodation cavity formed by the outer shell of the reagent supply mechanism.

[0096] Specifically, in this embodiment, the sample analyzer 10 includes a sample supply mechanism 11 for supplying samples; a sample dispensing mechanism 12 for dispensing samples into reaction vessels; a reagent supply mechanism 13 for supplying reagents; a reagent dispensing mechanism 14 for sucking reagents from a reagent container at a liquid suction level and discharging the sucked reagents into a reaction vessel at a liquid discharge level; and a measurement mechanism 15 for measuring a test solution formed at least by samples and reagents in the reaction vessel to obtain a measurement result. Among them, the reagent supply mechanism 13 includes: a storage member 131 provided with a plurality of reagent storage positions for placing reagent containers 20, the plurality of reagent storage positions are arranged in a first direction, at least two reagent storage positions are stacked in the vertical direction, and the first direction is different from the vertical direction; a reagent container transfer device 132 for transferring the reagent container 20 stored in the reagent storage position to the liquid suction level for liquid suction; a housing 133, the housing 133 forms a receiving cavity, the reagent storage position is arranged inside the receiving cavity, the liquid suction level is located outside the receiving cavity, and the housing 133 is further provided with an opening 1331, and the opening 1331 communicates the inside and the outside of the receiving cavity for the reagent container transfer device 132 to pass through when transferring the reagent container 20 stored in the reagent storage position to the liquid suction level; by setting the liquid suction level outside the receiving cavity, the structural avoidance between the reagent dispensing mechanism and the reagent supply mechanism can be effectively realized, so that the space occupied by the instrument can be further saved.

[0097] In some embodiments, the height of the liquid suction level is lower than the height of the reagent storage position with the highest height.

[0098] In some embodiments, the reagent container transfer device 132 includes a first reagent container transfer component 1321 and a second reagent container transfer component 1322. The first reagent container transfer component 1321 is used for transferring the reagent container 20 located at the reagent storage position to a first position, and the second reagent container transfer component 1322 is used for transferring the reagent container 20 located at the first position to the liquid suction level; wherein, the first position is located outside the receiving cavity.

[0099] The above are only the preferred embodiments of the present invention, and do not limit the patent scope of the present invention. Any equivalent structural transformation made under the inventive concept of the present invention by using the content of the specification and drawings of the present invention, or any direct / indirect application in other related technical fields is included in the patent protection scope of the present invention.

Claims

1. A sample analyzer, characterized in that, Comprising: A sample supply mechanism for supplying samples; A sample dispensing mechanism for dispensing samples into reaction vessels; A reagent supply mechanism for supplying reagents; A reagent dispensing mechanism for sucking reagents from a reagent container at a liquid suction level and discharging the sucked reagents into a reaction vessel at a liquid discharge level; A measurement mechanism for measuring a test solution formed at least by the sample and the reagent in the reaction vessel to obtain a measurement result; Wherein, the reagent supply mechanism includes: A storage member provided with a plurality of reagent storage positions for placing reagent containers, the plurality of reagent storage positions being arranged in a first direction, and at least two reagent storage positions being stacked in the vertical direction, the first direction being different from the vertical direction; A reagent container transfer device for transferring the reagent container stored in the reagent storage position to the liquid suction level for liquid suction; Wherein, the height of the liquid suction level is lower than the height of the reagent storage position with the highest height.

2. The sample analyzer according to claim 1, wherein, The liquid suction level is located outside the projection area of the reagent storage position in the vertical direction.

3. The sample analyzer according to claim 1, characterized in that, The reagent supply mechanism includes a housing that forms a receiving cavity, the reagent storage position is arranged inside the receiving cavity, the liquid suction level is located outside the receiving cavity, and the housing is further provided with an opening that communicates the inside and outside of the receiving cavity for the reagent container transfer device to pass through when transferring the reagent container stored in the reagent storage position to the liquid suction level.

4. The sample analyzer according to any one of claims 1-3, characterized in that, The reagent container transfer device includes a first reagent container transfer component and a second reagent container transfer component, the first reagent container transfer component is used for transferring the reagent container at the reagent storage position to a first position, and the second reagent container transfer component is used for transferring the reagent container at the first position to the liquid suction level.

5. The sample analyzer according to claim 4, characterized in that, The second reagent container transfer component includes a moving component and a reagent container carrying component, the reagent container carrying component is used for carrying the reagent container transferred by the first reagent container transfer component at the first position and carrying the reagent container for liquid suction, and the moving component is used for driving the reagent container carrying component to move between the first position and the liquid suction level.

6. The sample analyzer according to claim 4, wherein The direction in which the second reagent container transfer component moves between the first position and the liquid suction level is a second direction, and the second direction is a horizontal direction and perpendicular to the first direction.

7. The sample analyzer according to claim 4, wherein The first position is located within the projection area of the reagent storage position in the vertical direction, and / or, the first position is located inside the receiving cavity.

8. The sample analyzer according to claim 4, characterized in that, The second reagent container transfer component moves in a straight line in the second direction, the reagent dispensing mechanism moves in a straight line in a third direction, and the movement trajectory of the second reagent container transfer component intersects and is perpendicular to the movement trajectory of the reagent dispensing mechanism.

9. The sample analyzer according to claim 1, characterized in that, The liquid suction level is located within the projection area of the storage member in the vertical direction.

10. The sample analyzer according to claim 9, characterized in that, The liquid discharge position is outside the projection area of the reagent storage position in the vertical direction; or, the sample analyzer further includes a reaction vessel transfer device. The liquid discharge position is within the projection area of the reagent storage position in the vertical direction, and the reaction vessel transfer device is configured to transfer the reaction vessel that has completed liquid discharge at the liquid discharge position to outside the projection area of the reagent storage position in the vertical direction.

11. The sample analyzer according to claim 1, characterized in that, The reagent supply mechanism includes a housing that forms an accommodation cavity. The storage member and the reagent container transfer device are disposed in the accommodation cavity, and the liquid suction position is inside the accommodation cavity.

12. The sample analyzer according to claim 11, wherein, The housing is provided with an opening that communicates the inside and outside of the accommodation cavity. The liquid discharge position is outside the accommodation cavity, and the opening is for the reagent dispensing mechanism to move through between the liquid suction position and the liquid discharge position; or, the sample analyzer further includes a reaction vessel transfer device. The housing is provided with an opening that communicates the inside and outside of the accommodation cavity. The liquid discharge position is inside the accommodation cavity, and the reaction vessel transfer device is configured to transfer the reaction vessel that has completed liquid discharge at the liquid discharge position to outside the accommodation cavity through the opening.

13. The sample analyzer according to claim 1, characterized in that, The storage member includes at least two sub-storage members stacked in the vertical direction. The sub-storage member extends in a first direction and is provided with a plurality of partition plates in the first direction, and a plurality of reagent storage positions arranged in the first direction are formed between the partition plates.

14. The sample analyzer according to claim 1, wherein, The first direction is a horizontal direction perpendicular to the vertical direction.

15. A sample analyzer, characterized in that, Including: A sample supply mechanism for supplying a sample; A sample dispensing mechanism for dispensing the sample into a reaction vessel; A reagent supply mechanism for supplying a reagent; A reagent dispensing mechanism for sucking the reagent in the reagent container at the liquid suction position and discharging the sucked reagent into the reaction vessel at the liquid discharge position; A measurement mechanism for measuring the test solution formed at least by the sample and the reagent in the reaction vessel to obtain a measurement result; Wherein, the reagent supply mechanism includes: A storage member provided with a plurality of reagent storage positions for placing reagent containers. The plurality of reagent storage positions are arranged in a first direction, and at least two reagent storage positions are stacked in the vertical direction. The first direction is different from the vertical direction; A reagent container transfer device configured to transfer the reagent container stored in the reagent storage position to the liquid suction position for liquid suction; A housing that forms an accommodation cavity. The reagent storage position is disposed inside the accommodation cavity, and the liquid suction position is outside the accommodation cavity. The housing is further provided with an opening that communicates the inside and outside of the accommodation cavity for the reagent container transfer device to pass through when transferring the reagent container stored in the reagent storage position to the liquid suction position.

16. The sample analyzer according to claim 15, characterized in that, The reagent container transfer device includes a first reagent container transfer component and a second reagent container transfer component. The first reagent container transfer component is used to transfer the reagent container located at the reagent storage position to a first position, and the second reagent container transfer component is used to transfer the reagent container located at the first position to the liquid suction position; wherein, the first position is located outside the accommodation cavity.

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